Page last updated: 2024-08-21

formestane and fadrozole

formestane has been researched along with fadrozole in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.45)18.7374
1990's21 (67.74)18.2507
2000's6 (19.35)29.6817
2010's1 (3.23)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Cole, PA; Robinson, CH1
Egbuta, C; Ghosh, D; Lo, J1
Chen, JZ; Khan, MZI; Nazli, A; Uzair, M1
Bogart, MH; Lance, VA1
Borja, J; Pérez, N1
Holman, SD; Hutchison, JB; Wozniak, A1
Dowsett, M; Lønning, PE; Powles, TJ1
Braun, DG; Bullion, KA; Osawa, Y1
Santen, RJ1
Dowsett, M2
Bhatnagar, AS; Häusler, A; Krähenbühl, C; Monnet, G; Schenkel, L1
Miller, WR1
Brodie, A; Savinov, A; Wang, J; Yue, W1
Jeyasuria, P; Place, AR; Roosenburg, WM1
Cam, LL; Chen, S; Korzekwa, KR; Laughton, CA; Zhou, D1
Bhatnagar, AS; King, EJ; Purba, HS; Richert, P1
Kanno, H; Kim, T; Kitawaki, J; Noguchi, T; Okada, H; Yamamoto, T1
Höffken, K1
Gaillard, JL; Moslemi, S; Silberzahn, P1
Boyle, T; Dukes, M; Edwards, PN; Large, M; Smith, IK1
Almadhidi, J; Drosdowsky, MA; Moslemi, S; Séralini, GE1
Harada, N; Hatano, O1
Moslemi, S; Seralini, GE1
Coombes, RC1
Auvray, P; Bichat, F; Genne, P1
de Crémoux, P1
Buzdar, A; Howell, A1
Bria, E; Carlini, P; Cognetti, F; Di Cosimo, S; Fabi, A; Felici, A; Ferretti, G; Giannarelli, D; Milella, M; Mottolese, M; Nisticò, C; Papaldo, P; Ruggeri, EM; Terzoli, E1
Ioannidis, JP; Mauri, D; Pavlidis, N; Polyzos, NP1
Dutta, U; Pant, K1

Reviews

17 review(s) available for formestane and fadrozole

ArticleYear
Mechanism and inhibition of cytochrome P-450 aromatase.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:11

    Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry

1990
Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure-Function Perspective.
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Aromatase; Aromatase Inhibitors; Catalytic Domain; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship

2016
An overview on Estrogen receptors signaling and its ligands in breast cancer.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Breast Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ligands; Male; Receptors, Estrogen

2022
Aromatase inhibitors: clinical pharmacology and therapeutic implications in breast cancer.
    The Journal of international medical research, 1992, Volume: 20, Issue:4

    Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Letrozole; Nitriles; Triazoles

1992
Postmenopausal estrogen synthesis and metabolism: alterations caused by aromatase inhibitors used for the treatment of breast cancer.
    Journal of steroid biochemistry, 1990, Volume: 35, Issue:3-4

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Fadrozole; Female; Humans; Imidazoles; Menopause; Nitriles

1990
Recent progress in development of aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6

    Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Humans; Imidazoles; Nitriles

1990
Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer.
    The Journal of steroid biochemistry and molecular biology, 1990, Dec-20, Volume: 37, Issue:6

    Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Estrogen Antagonists; Fadrozole; Humans; Imidazoles; Nitriles

1990
Aromatase inhibitors in the treatment of advanced breast cancer.
    Cancer treatment reviews, 1989, Volume: 16, Issue:2

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Imidazoles; Neoplasms, Hormone-Dependent; Nitriles

1989
Experience with aromatase inhibitors in the treatment of advanced breast cancer.
    Cancer treatment reviews, 1993, Volume: 19 Suppl B

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Forecasting; Humans

1993
Aromatase inhibitors and their use in the adjuvant setting.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1998, Volume: 152

    Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Fadrozole; Female; Humans

1998
Drug and hormone interactions of aromatase inhibitors.
    Endocrine-related cancer, 1999, Volume: 6, Issue:2

    Topics: Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Enzyme Inhibitors; Estrogens; Fadrozole; Female; Humans; Letrozole; Male; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Sensitivity and Specificity; Tamoxifen; Triazoles

1999
[Preclinical evaluation of aromatase inhibitors antitumor activity].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles

2000
[Aromatase inhibitors: pharmacological aspects].
    Bulletin du cancer, 2000, Volume: 87 Spec No

    Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles

2000
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:9

    Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting

2001
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials.
    Cancer, 2005, Oct-01, Volume: 104, Issue:7

    Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles

2005
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
    Journal of the National Cancer Institute, 2006, Sep-20, Volume: 98, Issue:18

    Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles

2006
Aromatase inhibitors: past, present and future in breast cancer therapy.
    Medical oncology (Northwood, London, England), 2008, Volume: 25, Issue:2

    Topics: Aminoglutethimide; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles

2008

Other Studies

14 other study(ies) available for formestane and fadrozole

ArticleYear
Disruption of ovarian development in alligator embryos treated with an aromatase inhibitor.
    General and comparative endocrinology, 1992, Volume: 86, Issue:1

    Topics: Alligators and Crocodiles; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cyproterone; Cyproterone Acetate; Estradiol; Fadrozole; Female; Imidazoles; Male; Nitriles; Ovary; Tamoxifen; Testis

1992
In vitro potency and selectivity of the non-steroidal androgen aromatase inhibitor CGS 16949A compared to steroidal inhibitors in the brain.
    The Journal of steroid biochemistry and molecular biology, 1992, Volume: 43, Issue:4

    Topics: Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Birds; Fadrozole; Gerbillinae; Hypothalamus; In Vitro Techniques; Kinetics; Male; Testosterone

1992
Reversible inhibition of human placental microsomal aromatase by CGS 18320B and other non-steroidal compounds.
    Endocrine research, 1990, Volume: 16, Issue:2

    Topics: Androstenedione; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Fadrozole; Female; Glutethimide; Humans; Imidazoles; Kinetics; Microsomes; Molecular Structure; Nitriles; Placenta; Pregnancy

1990
An in vitro method to determine the selective inhibition of estrogen biosynthesis by aromatase inhibitors.
    Journal of steroid biochemistry, 1989, Volume: 33, Issue:1

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Cricetinae; Estrogen Antagonists; Estrogens; Estrus; Fadrozole; Female; Imidazoles; Kinetics; Luteinizing Hormone; Mesocricetus; Nitriles; Ovary; Progesterone; Testolactone; Testosterone

1989
Effect of aromatase inhibitors on growth of mammary tumors in a nude mouse model.
    Cancer research, 1995, Jul-15, Volume: 55, Issue:14

    Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Fadrozole; Female; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Organ Size; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles; Uterus

1995
Role of P-450 aromatase in sex determination of the diamondback terrapin, Malaclemys terrapin.
    The Journal of experimental zoology, 1994, Sep-15, Volume: 270, Issue:1

    Topics: Amino Acid Sequence; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Behavior, Animal; Cloning, Molecular; Estradiol; Fadrozole; Female; Humans; Male; Molecular Sequence Data; Sequence Homology, Amino Acid; Sex Differentiation; Turtles

1994
Mutagenesis study at a postulated hydrophobic region near the active site of aromatase cytochrome P450.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Amino Acid Sequence; Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; DNA Mutational Analysis; Dose-Response Relationship, Drug; Fadrozole; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship

1994
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:2-3

    Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity

1994
Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Aminoglutethimide; Androstenedione; Androstenols; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Fadrozole; Female; Humans; Kinetics; Tumor Cells, Cultured

1993
The synthesis of 19-norandrostenedione from dehydroepiandrosterone in equine placenta is inhibited by aromatase inhibitors 4-hydroxyandrostenedione and fadrozole.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1995, Volume: 112, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Dehydroepiandrosterone; Enzyme Inhibitors; Fadrozole; Female; Horses; Placenta; Pregnancy

1995
The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:4

    Topics: Adrenal Glands; Aminoglutethimide; Anastrozole; Androstenedione; Animals; Aromatase Inhibitors; Cortodoxone; Enzyme Inhibitors; Fadrozole; Female; Hormones; Humans; Macaca nemestrina; Male; Metyrapone; Nitriles; Organ Size; Potassium; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Sodium; Triazoles; Uterus

1996
Equine cytochrome P450 aromatase exhibits an estrogen 2-hydroxylase activity in vitro.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:1

    Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Fadrozole; Horses; Immune Sera; Kinetics; Male; Miconazole; Microsomes; Placenta; Steroid Hydroxylases; Substrate Specificity; Testis; Testosterone

1996
Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:4

    Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Carcinoma, Hepatocellular; Choriocarcinoma; Colforsin; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Fadrozole; Humans; Liver Neoplasms; Neoplasm Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Triazoles; Tumor Cells, Cultured

1998
Inhibition and inactivation of equine aromatase by steroidal and non-steroidal compounds. A comparison with human aromatase inhibition.
    Journal of enzyme inhibition, 1997, Volume: 12, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Enzyme Activation; Fadrozole; Horses; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Substrate Specificity

1997