Page last updated: 2024-08-21

formestane and dihydrotestosterone

formestane has been researched along with dihydrotestosterone in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (41.67)	18.7374
1990's	8 (33.33)	18.2507
2000's	6 (25.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H	1
Bellavance, E; Luu-The, V; Poirier, D	1
Lechuga, M; Motta, M; Zoppi, S	1
Coombes, RC; Davies, JH; Dowsett, M; Hedley, A; Jacobs, S; Shearer, RJ	1
Celotti, F; Lechuga, MJ; Martini, L; Melcangi, RC; Motta, M; Negri-Cesi, P; Poletti, A; Zoppi, S	1
Callard, GV; Schlinger, BA	1
Currie, JC; Henderson, A; Houston, PA; Payne, AP	1
Cocconi, M; Costantini, A; Martini, L; Motta, M; Natali, A; Serio, M; Zoppi, S	1
Albrecht, ED; Anderson, LD; Pepe, GJ; Wunsch, DM	1
Longcope, C; Mordes, JP; Orczyk, GP	1
Brodie, AM; Hammond, JO; Wing, LY	1
el Etreby, MF; Schröder, H; Ziegler, M	1
Martini, L; Motta, M; Zoppi, S	1
Coombes, RC; Easton, D; Goss, PE; Singh, D; Wilkinson, JR; Williams, JC	1
Brodie, AM; Martini, L; Motta, M; Zoppi, S	1
Berkovitz, GD; Brodie, AM; Brown, TR; Hsiang, YH; Migeon, CJ	1
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR	1
Bertolini, A; Sandrini, M; Vergoni, AV	1
Aguado, LI; Carrizo, DG; Deis, RP; Rastrilla, AM; Stati, AO; Stocco, CO; Tellería, CM	1
Burrello, N; Calogero, AE; D'Agata, R; Ossino, AM; Polosa, P	1
Damien, E; Lanyon, LE; Price, JS	1
Klinga, K; Mayer, D; Morfin, R; Schmitt, M; Schnarr, B	1
Chen, Q; Chihara, K; Kaji, H; Sugimoto, T	1
Bland, KI; Chaudry, IH; Samy, TS; Schneider, CP; Schwacha, MG	1

Reviews

1 review(s) available for formestane and dihydrotestosterone

Article	Year
Androgen metabolism in different target tissues. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aging; Androstenedione; Animals; Brain; Cricetinae; Dihydrotestosterone; Humans; Male; Pituitary Gland; Prostate; Prostatic Hyperplasia; Rats; Testosterone	1990

Trials

1 trial(s) available for formestane and dihydrotestosterone

Article	Year
Aromatase inhibition: 4-hydroxyandrostenedione (4-OHA, CGP 32349) in advanced prostatic cancer. British journal of cancer, 1992, Volume: 66, Issue:1 Topics: Aged; Androstenedione; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Humans; Male; Neoplasm Staging; Prostatic Neoplasms; Testosterone; Time Factors	1992

Other Studies

22 other study(ies) available for formestane and dihydrotestosterone

Article	Year
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22 Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts	2003
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23 Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity	2009
Selective inhibition of the 5 alpha-reductase of the rat epididymis. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 42, Issue:5 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Epididymis; In Vitro Techniques; Male; Molecular Structure; Pyrazoles; Rats; Rats, Inbred Strains; Steroids	1992
Aromatization mediates aggressive behavior in quail. General and comparative endocrinology, 1990, Volume: 79, Issue:1 Topics: 5-alpha Reductase Inhibitors; Aggression; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Azasteroids; Behavior, Animal; Coturnix; Dihydrotestosterone; Estradiol; Female; Flutamide; Hypothalamus; Male; Motor Activity; Nitromifene; Preoptic Area; Quail; Testosterone	1990
Neonatal hormone manipulations and the maintenance of perineal muscles and their motor neurones in Albino Swiss rats. Journal of reproduction and fertility, 1990, Volume: 89, Issue:2 Topics: Androgen Antagonists; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Estradiol; Female; Gonadal Steroid Hormones; Male; Motor Neurons; Muscles; Organ Size; Perineum; Rats; Rats, Inbred Strains; Sex Characteristics; Testosterone	1990
In vitro effects of an aromatase inhibitor on 5 alpha-reductase activity in human hypertrophic prostatic tissue. The Journal of clinical endocrinology and metabolism, 1986, Volume: 63, Issue:1 Topics: 5-alpha Reductase Inhibitors; Aged; Androstane-3,17-diol; Androstenedione; Aromatase Inhibitors; Azasteroids; Dihydrotestosterone; Humans; In Vitro Techniques; Male; Middle Aged; Prostatic Hyperplasia; Testosterone	1986
Regulation of progesterone formation by human placental cells in culture. Endocrinology, 1986, Volume: 119, Issue:3 Topics: Androstenedione; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; DNA; Estradiol; Estrogen Antagonists; Ethamoxytriphetol; Female; Humans; Placenta; Pregnancy; Progesterone; Time Factors	1986
Aromatase activity in a rat Leydig cell tumor. Endocrinology, 1987, Volume: 120, Issue:4 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Bucladesine; Chorionic Gonadotropin; Dihydrotestosterone; Estradiol; Estrone; Leydig Cell Tumor; Male; Neoplasm Transplantation; Rats; Rats, Inbred WF; Testicular Neoplasms; Testosterone; Tetradecanoylphorbol Acetate; Water	1987
Differential responses of sex steroid target tissues of rats treated with 4-hydroxyandrostenedione. Endocrinology, 1988, Volume: 122, Issue:6 Topics: Androstenedione; Animals; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Kinetics; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Uterus	1988
Aromatase-inhibitors of the androstenedione-type activate the 17 beta-hydroxysteroid-dehydrogenase in the rat testis tissue suspension model. Journal of steroid biochemistry, 1988, Volume: 31, Issue:4B Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase Inhibitors; Culture Techniques; Dihydrotestosterone; Enzyme Activation; Male; Rats; Structure-Activity Relationship; Testis; Testosterone	1988
Studies on the possible existence of two 5 alpha-reductases in the rat prostate. Journal of steroid biochemistry, 1986, Volume: 24, Issue:1 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Age Factors; Androstenedione; Animals; Dihydrotestosterone; Isoenzymes; Male; Prostate; Rats; Rats, Inbred Strains; Testosterone	1986
Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer research, 1986, Volume: 46, Issue:9 Topics: Aminoglutethimide; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Danazol; Dihydrotestosterone; Female; Humans; Mammary Neoplasms, Experimental; Menopause; Methylnitrosourea; Ovariectomy; Rats; Tamoxifen	1986
Effect of 1,4,6-androstatriene-3,17-dione (ATD), 4-hydroxy-4-androstene-3,17-dione (4-OH-A) and 4-acetoxy-4-androstene-3,17-dione (4-Ac-A) on the 5 alpha-reduction of androgens in the rat prostate. Journal of steroid biochemistry, 1986, Volume: 25, Issue:4 Topics: Androgens; Androstatrienes; Androstenedione; Animals; Dihydrotestosterone; In Vitro Techniques; Male; Oxidation-Reduction; Prostate; Rats; Rats, Inbred Strains; Testosterone	1986
The influence of 4-hydroxy-4-androstene-3,17-dione on androgen metabolism and action in cultured human foreskin fibroblasts. Journal of steroid biochemistry, 1987, Volume: 26, Issue:1 Topics: Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Fibroblasts; Humans; Kinetics; Male; Oxidoreductases; Penis; Receptors, Androgen	1987
Comparative studies of aromatase inhibitors in cultured human breast cancer cells. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone	1982
Lack of influence of aromatase and 5 alpha-reductase inhibition on [3H]imipramine binding in the male rat brain. Journal of endocrinological investigation, 1993, Volume: 16, Issue:9 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Azasteroids; Brain; Dihydrotestosterone; Gonadal Steroid Hormones; Imipramine; Male; Rats; Rats, Wistar	1993
Dual regulation of luteal progesterone production by androstenedione during spontaneous and RU486-induced luteolysis in pregnant rats. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 55, Issue:3-4 Topics: 17-Hydroxysteroid Dehydrogenases; 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Adrenalectomy; Androstenedione; Animals; Aromatase Inhibitors; Cells, Cultured; Corpus Luteum; Dihydrotestosterone; Estradiol; Female; Hormone Antagonists; Luteolysis; Luteolytic Agents; Menstruation-Inducing Agents; Mifepristone; Organ Size; Polyunsaturated Alkamides; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Rats, Wistar; Testosterone	1995
Activin-A stimulates hypothalamic gonadotropin-releasing hormone release by the explanted male rat hypothalamus: interaction with inhibin and androgens. The Journal of endocrinology, 1998, Volume: 156, Issue:2 Topics: Activins; Androstenedione; Animals; Aromatase Inhibitors; Dihydrotestosterone; Enzyme Inhibitors; Feedback; Gonadotropin-Releasing Hormone; Hypothalamus; Inhibins; Male; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Testosterone	1998
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:11 Topics: Androgen Antagonists; Androstenedione; Animals; Antibodies; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flutamide; Fulvestrant; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Stress, Mechanical; Tamoxifen; Testosterone; Thymidine	2000
Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol. Molecular and cellular endocrinology, 2001, Feb-28, Volume: 173, Issue:1-2 Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Chromatography, Thin Layer; Dehydroepiandrosterone; Dexamethasone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Immunoassay; Mitogens; Tamoxifen; Transcriptional Activation; Transfection; Tumor Cells, Cultured	2001
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor. FEBS letters, 2001, Feb-23, Volume: 491, Issue:1-2 Topics: Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Cell Division; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flutamide; Fulvestrant; Glucuronates; Mice; Mice, Inbred ICR; Osteoclasts; Parathyroid Hormone; Receptors, Androgen; Teriparatide; Testosterone	2001
Androgen-mediated modulation of macrophage function after trauma-hemorrhage: central role of 5alpha-dihydrotestosterone. Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 95, Issue:1 Topics: Androgens; Androstenedione; Animals; Cell Separation; Cell Survival; Cells, Cultured; Cytokines; Dihydrotestosterone; Gene Expression; Hemorrhage; Kupffer Cells; Macrophages; Male; Mice; Mice, Inbred C3H; Reverse Transcriptase Polymerase Chain Reaction; Shock, Hemorrhagic; Spleen; Testosterone; Wounds and Injuries	2003