formaldehyde and thiophenes

formaldehyde has been researched along with thiophenes in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's3 (11.54)18.2507
2000's5 (19.23)29.6817
2010's15 (57.69)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Cowan, A; Wheeler-Aceto, H1
Cowan, A; Ianone, M; Porreca, F; Wheeler, H1
Carruette, A; Garret, C; Moussaoui, S1
Grouhel, A; Wettstein, JG1
Nivsarkar, M; P X, F; Padh, H; Patel, M; Pillai, AD; Rathod, PD; Sudarsanam, V; Vasu, KK1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Berrino, L; de Novellis, V; Maione, S; Marabese, I; Mariani, L; Oliva, P; Palazzo, E; Rossi, F; Scafuro, M; Siniscalco, D1
Ansell, L; Baxter, JA; Beckett, SR; Chapman, V; Finn, DP; Fone, KC; Marsden, CA1
Munro, G1
Aliaga, M; Bardin, L; Depoortère, R; Gregoire, S; Ladure, P; Malfetes, N; Newman-Tancredi, A; Vitton, O1
Görls, H; Imhof, W; Klobes, O; Maiti, BK1
Dyhr, H; Erichsen, HK; Hansen, MK; Marcher, L; Munro, G; Sheykhzade, M; Storm, A1
Hammarström, P; Lindgren, M; Nilsson, KP1
Ashour, HM; El-Ashmawy, IM; Rizk, OH; Shaaban, OG1
El-Ashmawy, IM; El-Hawash, SA; El-Tombary, AA; Habib, NS; Shaaban, OG; Soliman, R1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR1
Dong, YL; Gu, ZX; Lu, GJ; Sun, YH; Wang, W; Wang, YT; Wu, SX; Yang, J; Zhao, GL1
Du, X; Jiang, Y; Li, X; Tai, H; Xie, G1
Filipek, B; Sałat, K1
Abelson, KS; Jørgensen, KB; Kanui, TI; Krogh-Jensen, K; Pickering, DS1
Cui, J; He, C; Men, G; Xu, B; Zhao, J1
El-Hawash, SA; El-Messmary, H; El-Miligy, MM; Hazzaa, AA; Nassra, RA1
El-Hawash, SAM; El-Messmary, H; El-Miligy, MMM; Hazzaa, AA; Nassra, RA1
Kumar, S; Singh, AK; Vinayak, M1
Cho, N; Hara, H; Hoffman, I; Homma, M; Imada, T; Iwai, K; Iwata, K; Kurasawa, O; Miyazaki, T; Nomura, T; Oguro, Y; Ohashi, A; Ohori, M; Skene, R; Sugimoto, H; Uchiyama, N; Yamamoto, Y1
Finn, DP; Gaspar, JC; Llorente-Berzal, A; Okine, BN; Roche, M1

Other Studies

26 other study(ies) available for formaldehyde and thiophenes

ArticleYear
Standardization of the rat paw formalin test for the evaluation of analgesics.
    Psychopharmacology, 1991, Volume: 104, Issue:1

    Topics: Analgesics; Animals; Aspirin; Behavior, Animal; Decerebrate State; Foot; Formaldehyde; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Reference Standards; Thiophenes

1991
Comparison of PD 117302, a kappa agonist, and morphine on colonic transit and formalin-induced pain in rats.
    Proceedings of the Western Pharmacology Society, 1989, Volume: 32

    Topics: Animals; Colon; Dose-Response Relationship, Drug; Formaldehyde; Gastrointestinal Transit; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes

1989
Further evidence that substance P is a mediator of both neurogenic inflammation and pain: two phenomena inhibited either by postsynaptic blockade of NK1 receptors or by presynaptic action of opioid receptor agonists.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Anticonvulsants; Electric Stimulation; Formaldehyde; Indoles; Inflammation; Isoindoles; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Thiophenes

1993
Opioid antagonist profile of SC nor-binaltorphimine in the formalin paw assay.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes

1996
Novel drug designing approach for dual inhibitors as anti-inflammatory agents: implication of pyridine template.
    Biochemical and biophysical research communications, 2003, Jan-31, Volume: 301, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Design; Edema; Formaldehyde; Inflammation; Molecular Structure; Pyridines; Rats; Thiophenes

2003
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Acetates; Acrylamides; Animals; Benzyl Compounds; Dimethyl Sulfoxide; Extracellular Fluid; Formaldehyde; gamma-Aminobutyric Acid; Glutamic Acid; Hyperalgesia; Injections, Intraventricular; Male; Mice; Microdialysis; Misoprostol; Naphthalenes; Pain Measurement; Periaqueductal Gray; Prostaglandin Antagonists; Receptors, Prostaglandin E; Thiophenes; Triazoles; Xanthones

2006
The effects of pharmacological blockade of the 5-HT(6) receptor on formalin-evoked nociceptive behaviour, locomotor activity and hypothalamo-pituitary-adrenal axis activity in rats.
    European journal of pharmacology, 2007, Aug-13, Volume: 569, Issue:1-2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Corticosterone; Defecation; Dose-Response Relationship, Drug; Formaldehyde; Grooming; Hypothalamo-Hypophyseal System; Injections, Intraperitoneal; Male; Motor Activity; Pain; Pain Measurement; Pituitary-Adrenal System; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin Antagonists; Stress, Physiological; Sulfonamides; Thiophenes; Time Factors

2007
Dopamine D(1) and D(2) receptor agonism enhances antinociception mediated by the serotonin and noradrenaline reuptake inhibitor duloxetine in the rat formalin test.
    European journal of pharmacology, 2007, Dec-01, Volume: 575, Issue:1-3

    Topics: Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Formaldehyde; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Selective Serotonin Reuptake Inhibitors; Thiophenes; Time Factors

2007
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats.
    Neuroscience research, 2010, Volume: 66, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Analgesics; Analysis of Variance; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electroshock; Formaldehyde; gamma-Aminobutyric Acid; Male; Milnacipran; Pain; Pain Measurement; Pregabalin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Thiophenes; Vocalization, Animal

2010
A straightforward and generalizable synthetic methodology for the synthesis of ruthenium(II) complexes with thioether ligands from either Ru(III) or Ru(0) precursors.
    Dalton transactions (Cambridge, England : 2003), 2010, Jun-28, Volume: 39, Issue:24

    Topics: Chloroform; Coordination Complexes; Crystallography, X-Ray; Formaldehyde; Ligands; Molecular Conformation; Ruthenium; Sulfides; Thiophenes

2010
The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Amines; Analgesics; Animals; Capsaicin; Cyclohexanecarboxylic Acids; Disease Models, Animal; Duloxetine Hydrochloride; Exploratory Behavior; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Locomotion; Male; Morphine; Neuralgia; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiophenes

2012
A pentameric luminescent-conjugated oligothiophene for optical imaging of in vitro-formed amyloid fibrils and protein aggregates in tissue sections.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 849

    Topics: Acetates; Amyloid; Amyloid beta-Peptides; Animals; Brain; Cattle; Drosophila melanogaster; Formaldehyde; Humans; Insulin; Kinetics; Luminescent Agents; Mice; Molecular Imaging; Optical Phenomena; Paraffin Embedding; Peptide Fragments; Polymers; Protein Multimerization; Protein Structure, Secondary; Recombinant Proteins; Thiophenes; Tissue Fixation

2012
Synthesis and biological evaluation of thieno [2',3':4,5]pyrimido[1,2-b][1,2,4]triazines and thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidines as anti-inflammatory and analgesic agents.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Male; Molecular Structure; Pyrimidines; Rats; Rats, Wistar; Structure-Activity Relationship; Thiophenes; Triazines; Triazoles

2013
Synthesis and biological evaluation of some novel thieno[2,3-d] pyrimidine derivatives as potential anti-inflammatory and analgesic agents.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2013, Volume: 9, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Granuloma; Male; Molecular Structure; Pain Measurement; Pyrimidines; Rats; Rats, Wistar; Tail; Thiophenes; Turpentine

2013
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes

2013
Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Analgesics; Analysis of Variance; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Duloxetine Hydrochloride; Formaldehyde; Hindlimb; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Motor Activity; Nociceptive Pain; Pain Measurement; Pyrazoles; Sulfonamides; Thiophenes

2013
The enhanced formaldehyde-sensing properties of P3HT-ZnO hybrid thin film OTFT sensor and further insight into its stability.
    Sensors (Basel, Switzerland), 2015, Jan-19, Volume: 15, Issue:1

    Topics: Formaldehyde; Gases; Microscopy, Atomic Force; Organic Chemicals; Photoelectron Spectroscopy; Thiophenes; Transistors, Electronic; Zinc Oxide

2015
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice.
    Journal of Zhejiang University. Science. B, 2015, Volume: 16, Issue:3

    Topics: Acetanilides; Analgesics; Animals; Benzamides; Capsaicin; Cold Temperature; Disease Models, Animal; Formaldehyde; Hyperalgesia; Isothiocyanates; Male; Mice; Neuralgia; Oximes; Paclitaxel; Pain Measurement; Purines; Thiophenes; Touch; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPM Cation Channels; TRPV Cation Channels

2015
Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber).
    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2016, Volume: 202, Issue:1

    Topics: Animals; Female; Formaldehyde; Male; Mole Rats; Muscarinic Agonists; N-Methylscopolamine; Nociception; Pyridines; Radioligand Assay; Radiopharmaceuticals; Receptors, Muscarinic; Spinal Cord; Thiadiazoles; Thiophenes; Tritium

2016
Phenolic resin-derived activated carbon-supported divalent metal as efficient adsorbents (M-C, M=Zn, Ni, or Cu) for dibenzothiophene removal.
    Environmental science and pollution research international, 2017, Volume: 24, Issue:1

    Topics: Adsorption; Air Pollutants; Cations, Divalent; Charcoal; Copper; Formaldehyde; Gasoline; Kinetics; Models, Theoretical; Nickel; Phenols; Polymers; Temperature; Thiophenes; Zinc

2017
New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    Future medicinal chemistry, 2017, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Formaldehyde; Humans; Lipoxygenase Inhibitors; Molecular Docking Simulation; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiophenes

2017
New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    Bioorganic chemistry, 2017, Volume: 72

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Benzofurans; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Formaldehyde; Lipoxygenase Inhibitors; Male; Molecular Docking Simulation; Molecular Structure; Rats; Rats, Wistar; Rhodanine; Structure-Activity Relationship; Thiophenes

2017
ML171, a specific inhibitor of NOX1 attenuates formalin induced nociceptive sensitization by inhibition of ROS mediated ERK1/2 signaling.
    Neurochemistry international, 2019, Volume: 129

    Topics: Animals; Formaldehyde; Male; MAP Kinase Signaling System; Mice; NADPH Oxidase 1; NADPH Oxidases; Proto-Oncogene Proteins c-fos; Reactive Oxygen Species; Signal Transduction; Sulfonamides; Thiophenes; Up-Regulation

2019
Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-
    Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3

    Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Proteins; Cell Line, Tumor; Drug Design; Drug Discovery; Formaldehyde; Humans; Mice; Molecular Docking Simulation; Molecular Structure; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazolones; Pyrimidines; Pyrimidinones; Quinuclidines; Structure-Activity Relationship; Thiophenes; Xenograft Model Antitumor Assays

2020
Pharmacological Blockade of PPAR Isoforms Increases Conditioned Fear Responding in the Presence of Nociceptive Tone.
    Molecules (Basel, Switzerland), 2020, Feb-24, Volume: 25, Issue:4

    Topics: Analgesia; Anilides; Animals; Conditioning, Psychological; Extinction, Psychological; Fear; Formaldehyde; Freezing Reaction, Cataleptic; Gene Expression; Male; Nociceptive Pain; Oxazoles; PPAR alpha; PPAR delta; PPAR gamma; PPAR-beta; Rats; Rats, Sprague-Dawley; Sulfones; Thiophenes; Tyrosine

2020