formaldehyde has been researched along with naloxone in 184 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (8.15) | 18.7374 |
| 1990's | 50 (27.17) | 18.2507 |
| 2000's | 65 (35.33) | 29.6817 |
| 2010's | 48 (26.09) | 24.3611 |
| 2020's | 6 (3.26) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| North, MA | 1 |
| Liebeskind, JC; Marek, P; Vaccarino, AL | 1 |
| Bugorskiĭ, GV; Privalova, IL; Sheveleva, OA; Zav'ialov, AV | 1 |
| Liebeskind, JC; Marek, P; Sternberg, W; Vaccarino, AL | 1 |
| Melzack, R; Plamondon, H; Vaccarino, AL | 1 |
| Basbaum, AI; Gogas, KR; Levine, JD; Presley, RW | 1 |
| Goldstein, BD; McCarson, KE | 2 |
| Cowan, A; Larson, AA; Murray, CW | 1 |
| Arias, A; Oya, S; Vaquero, J; Zurita, M | 1 |
| Dickenson, A; Haley, J; Ketchum, S | 1 |
| Hughes, RA; Sufka, KJ | 1 |
| Ansuategui, M; Feria, M; Naharro, L | 1 |
| Abbott, FV | 1 |
| Abbott, FV; Franklin, KB; Libman, RB | 1 |
| Bragin, EO | 1 |
| Kocher, L | 1 |
| Melzack, R; Tasker, RA; Vaccarino, AL | 1 |
| Kuraishi, Y; Satoh, M; Sugimoto, M; Takagi, H | 1 |
| Inoki, R; Ohkubo, T; Saito, K; Shibata, M; Takahashi, H | 1 |
| Fanselow, MS | 2 |
| Aya, K; Inase, M; Nakahama, H; Shima, K; Yamamoto, M | 1 |
| Abbott, FV; Connell, B; Franklin, KB | 1 |
| Murano, T; Nishino, H; Yamamoto, H; Yano, I | 1 |
| Goldstein, BD; Holland, LN | 1 |
| Berger, F; Chayvialle, JA; Chéry-Croze, S; Gorry, F; Miampamba, M | 1 |
| Katsumata, K; Kisara, K; Sakurada, S; Sakurada, T; Tan-No, K; Yogo, H | 1 |
| Katsumata, K; Kisara, K; Manome, Y; Ohba, M; Sakurada, S; Sakurada, T; Tan-No, K | 1 |
| Blommaert, A; Fournié-Zaluski, MC; Noble, F; Roques, BP | 1 |
| Cadet, R; Luccarini, P; Saade, M; Woda, A | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Gibert-Rahola, J; Maldonado, R; Mellado, M; Micó, JA; Valverde, O | 1 |
| Ayala, J; Del Valle, M; Fuente, T; Hernández, LC; Iglesias, L; López, JM; Seijo, F | 1 |
| Harris, JA; Westbrook, RF | 1 |
| Kaneto, H; Rahman, AF; Takahashi, M | 1 |
| Abram, SE; Olson, EE | 1 |
| Cunha, GM; Rao, VS; Silva, MA; Viana, GS | 1 |
| Couret, LC; Vaccarino, AL | 1 |
| Cowan, A; Wheeler-Aceto, H | 1 |
| Kanui, TI; Karim, F; Mbugua, S | 1 |
| Cowan, A; Hunter, JC; Kovelowski, CJ; Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Wheeler-Aceto, H | 1 |
| Basbaum, AI; Gogas, KR; Levine, JD | 1 |
| Eisenberg, E; Strassman, AM; Vos, BP | 1 |
| Keana, JF; Kwon, IS; Lutfy, K; Marek, P; Sadowski, B; Weber, E | 1 |
| Grouhel, A; Wettstein, JG | 1 |
| Basbaum, AI; Peterson, MA; Taylor, BK | 2 |
| Ottani, A; Pini, LA; Sandrini, M; Vitale, G | 1 |
| Mathur, R; Mena, NB; Nayar, U | 1 |
| Pini, LA; Sandrini, M; Vitale, G | 1 |
| Hagihira, S; Taenaka, N; Yoshiya, I | 1 |
| Takeshita, N; Yamaguchi, I | 1 |
| Sagen, J; Siegan, JB | 1 |
| Brune, K; Erb, K; Geisslinger, G; Liebel, JT; Tegeder, I; Zeilhofer, HU | 1 |
| Elliott, KJ; Inturrisi, CE; Shimoyama, M; Shimoyama, N | 1 |
| Calixto, JB; Santos, AR | 1 |
| Franklin, KB; Manning, BH | 1 |
| Khanna, S; Zheng, F | 1 |
| Li, HD; Li, XC; Ruan, HZ | 1 |
| Coderre, TJ; Gilron, I; Quirion, R | 1 |
| Arai, K; Furuta, S; Hayashi, T; Katsuyama, S; Kisara, K; Onodera, K; Sakurada, S; Sato, T; Yonezawa, A | 1 |
| Bowersox, SS; Gao, D; Pettus, M; Wang, YX | 1 |
| Abe, K; Arai, T; Ibii, N; Ito, S; Minami, T; Mori, H; Nakano, H; Okuda-Ashitaka, E; Tokumura, M | 1 |
| Fernández, MA; García, MD; Sáenz, MT; Tornos, MP | 1 |
| Aloisi, AM; Ceccarelli, I | 1 |
| Harada, A; Honda, K; Kamiya, H; Takano, Y | 1 |
| Matos, FJ; Pinho, RS; Vale, TG; Viana, GS | 1 |
| Aguirre-Bañuelos, P; Granados-Soto, V; Mixcoatl-Zecuatl, T | 1 |
| Arai, K; Furuta, S; Hayashi, T; Katsuyama, S; Kisara, K; Miyazaki, S; Onodera, K; Sakurada, S; Sato, T; Yonezawa, A | 1 |
| Abdollahi, M; Habibi, L; Nikfar, S | 1 |
| Alloui, A; Eschalier, A; Jourdan, D | 1 |
| Aguirre-Bañuelos, P; Granados-Soto, V | 1 |
| Sahebgharani, M; Shaverdian, S; Zarrindast, MR | 1 |
| Hassanpour, M; Nayebi, AR; Rezazadeh, H | 1 |
| Changeux, JP; Damaj, MI; Epping-Jordan, MP; Marubio, LM; Merlo-Pich, E; Salmon, AM | 1 |
| Almeida, CE; Barcellos, IB; Bonacorso, HG; de Bastiani, J; de Mello, CF; de Oliveira, MR; de Souza, FR; Fighera, MR; Flores, AE; Lima, TT | 1 |
| Becker, C; Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Lapeyre, S; Mauborgne, A | 1 |
| Fang, L; Kawase, M; Morimoto, Y; Ohmori, S; Saito, S | 1 |
| Dafny, N; Ma, J; Qiao, JT | 1 |
| Almeida, KR; Coelho, MM; Dolabella, SS; França, DS; Martinelli, C; Souza, AL | 1 |
| Dougherty, PM; Grabow, TS | 1 |
| Castillo-Henkel, C; Granados-Soto, V; Medina-Santillán, R; Medina-Tato, DA; Ochoa-Cetina, L; Reyes-García, G; Rodríguez-Silverio, J; Terán-Rosales, F; Torres-López, JE | 1 |
| Lutz, EA; Shannon, HE | 1 |
| Chidiac, JJ; Hawwa, NN; Jabbur, SJ; Jurjus, AR; Massaad, CA; Rifai, K; Saadé, NE | 1 |
| Furuta, S; Hayashi, T; Honma, I; Miyazaki, S; Onodera, K; Sakurada, S; Yonezawa, A | 1 |
| Hao, S; Iwasaki, H; Mamiya, K; Takahata, O | 1 |
| Cechinel-Filho, V; Corrêa, R; de Campos, F; de Souza, MM; Nunes, RJ; Yunes, RA | 1 |
| Castillo-Henkel, C; Granados-Soto, V; Medina-Santillán, R; Reyes-García, G; Terán-Rosales, F | 1 |
| Nakama-Kitamura, M | 1 |
| Lu, CR; Qi, WX | 1 |
| Crul, BJ; De Jongh, RF; Meert, TF; Vinken, P; Vissers, KC | 1 |
| Donovan, DM; Meyer, RA; Raja, SN; Tall, JM; Tao, YX; Zhao, CS | 1 |
| Ramaswamy, S; Reddy, PM; Shashindran, CH; Sivasanker, M | 1 |
| Ahn, DK; Bae, YC; Choi, HS; Ju, JS; Jung, CY; Kim, SK; Lee, HJ | 1 |
| Gao, WC; Nie, H; Qiao, JT; Wang, H; Zhang, RX | 1 |
| Hong, Y; Huang, H; Zeng, X | 1 |
| Aguirre-Bañuelos, P; Arellano-Guerrero, A; de Pozos-Guillén, AJ; Hoyo-Vadillo, C; Pérez-Urizar, J | 1 |
| Chapman, V; Haynes, L; Marsden, CA; Morris, PG; Prior, MJ; Shah, YB | 1 |
| Andrade, MM; Assreuy, AM; Cardi, BA; Carvalho, KM; Criddle, DN; de Freitas, CD; Lima, SR; Matos, SG; Patrocínio, MC; Ramos, MV; Soares, PM; Vasconcelos, SM | 1 |
| Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J | 1 |
| Bianchi, B; Faltynek, CR; Honore, P; Jarvis, MF; McDonald, HA; McGaraughty, S; Mikusa, J; Wismer, CT; Zhu, CZ | 1 |
| Baeyens, JM; Cendán, CM; Portillo-Salido, E; Pujalte, JM | 1 |
| Azad, EM; Heidari, MR; Mehrabani, M | 1 |
| Andrade, Ada S; de Castro, M; Gameiro, GH; Pereira, LF; Tambeli, CH; Veiga, MC | 1 |
| Alagheband, P; Fazli-Tabaei, S; Rastegar, F; Safari, S; Samie, HR; Yahyavi, SH; Zarrindast, MR | 1 |
| Chugh, C; Jain, H; Mediratta, PK; Rathi, N; Reeta, Kh; Sharma, KK | 1 |
| Aboufatima, R; Benharref, A; Chait, A; Dalal, A; Elhabazi, K; Zyad, A | 1 |
| Dafny, N; Gao, WC; Nie, H; Qiao, JT; Wang, H; Zhang, RX | 1 |
| Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH | 1 |
| Fernandes, PD; Gomes, NM; Leitão, SG; Marinho, BG; Matheus, ME; Miranda, LS; Vasconcellos, ML | 1 |
| Asgari-Afshar, A; Sahebgharani, M; Zarrindast, MR | 1 |
| Avila-Peña, D; Peña, N; Quintero, L; Suárez-Roca, H | 1 |
| Andrade, EL; Calixto, JB; Ferreira, J; Santos, AR | 1 |
| Clemente-Napimoga, JT; Cunha, FQ; Cunha, TM; Ferrari, LF; Ferreira, SH; Napimoga, MH; Parada, CA; Souza, GR; Verri, WA | 1 |
| García Bermejo, LF; Murillo Pulgarín, JA; Sánchez García, MN | 1 |
| García Bermejo, LF; Lemus Gallego, JM; Murillo Pulgarín, JA; Sánchez García, MN | 1 |
| de Almeida, RN; De Sousa, DP; Oliveira, Fde S | 1 |
| Benedito, RB; de Almeida, RN; de Araújo, DA; de Sousa, DP; Gonçalves, JC; Oliveira, Fde S | 1 |
| Hussain, MK; Israf, DA; Mohamad, AS; Moin, S; Somchit, MN; Sulaiman, MR; Zakaria, ZA | 1 |
| Juma, F; Kanui, TI; Maloiy, GM; Olongida Ole Miaron, J; Towett, PK | 1 |
| Ray, SB; Yaksh, TL | 1 |
| An, TH; Hua, CJ; Huang, LJ; Kim, WM; Kim, YO; Lee, HG; Park, KD; Yoon, MH | 1 |
| Babaei, M; Jadidi, M; Jarrahi, M; Sadeghi, H; Taherian, AA; Vafaei, AA | 1 |
| Calixto, JB; Chaves, J; Ferreira, VM; Guginski, G; Luiz, AP; Martins, DF; Massaro, M; Mattos, RW; Santos, AR; Silva, MD; Silveira, D | 1 |
| Amresh, G; Rao, CV; Singh, S; Zeashan, H | 1 |
| Amaral, JF; Araújo, FL; Barbosa-Filho, JM; de Sousa, FC; Gutierrez, SJ; Leite, CP; Melo, CT; Moura, BA; Rocha, NF; Vasconcelos, SM; Viana, GS | 1 |
| Fabbri, A; Falzano, L; Fiorentini, C; Luvisetto, S; Malorni, W; Marinelli, S; Pavone, F; Straface, E | 1 |
| Haghparast, A; Khani, A; Lashgari, R; Motamedi, F; Naderi, N | 1 |
| Israf, DA; Lajis, N; Moin, S; Mokhtar, AF; Shaik Mossadeq, WM; Sulaiman, MR; Tengku Mohamad, TA; Yusof, M; Zakaria, ZA | 1 |
| Amirabadi, A; Azimzadeh, BS; Eskandarizadeh, A; Foroumadi, A; Heidari, MR; Samzadeh-Kermani, A | 1 |
| Arthuri, MT; Fischer, L; Tambeli, CH; Torres-Chávez, KE | 1 |
| Amendoeira, FC; Barreto, E; Calheiros, AS; Frutuoso, VS; Martins, MA; Rodarte, RS; Silva, JP; Silva, PM; Souza, CZ | 1 |
| Hsu, SF; Huang, YJ; Li, YL; Sun, WZ; Wang, CC; Wen, YR; Yeh, GC | 1 |
| Hashim, P; Israf, DA; Khalid, S; Mohamad, AS; Rejab, S; Shaberi, AM; Shaik Mossadeq, WM; Sulaiman, MR; Zakaria, ZA | 1 |
| Fujita-Hamabe, W; Mankura, M; Nakamoto, K; Nishinaka, T; Tokuyama, S | 1 |
| Khodorova, A; Strichartz, GR | 1 |
| Bezerra, AM; Canuto, KM; Fonsêca, KS; Góes, JG; Leal, LK; Pierdoná, TM; Silveira, ER; Viana, GS | 1 |
| Dimitrov, EL; Petrus, E; Usdin, TB | 1 |
| Cha, DS; Eun, JS; Jeon, H | 1 |
| Couto, VM; Dias, DF; Dos Santos, MH; Giusti-Paiva, A; Nascimento, CG; Soncini, R; Vilela, FC | 1 |
| Choi, JI; Kim, CM; Kim, KS; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Erfanparast, A; Farshid, AA; Khalilzadeh, E; Tamaddonfard, E | 1 |
| Cha, DS; Jeon, H; Park, HJ | 1 |
| Feng, YL; Lin, HM; Liu, YL; Qin, ZH; Reid, PF; Shi, GN; Yang, SL | 1 |
| Alves-da-Silva, G; Dias, DF; Giusti-Paiva, A; Orlandi, L; Santa-Cecília, FV; Vilela, FC | 1 |
| Bum, EN; Dawe, A; De Waard, M; Dimo, T; Dzeufiet, PD; Nguimbou, RM; Sidiki, N; Taïwe, GS; Talla, E | 1 |
| Azhdari-Zarmehri, H; Erami, E; Haghparast, A; Heidari-Oranjaghi, N | 1 |
| Cavalcante Melo, FH; Citó, Mdo C; de Sousa, DP; de Sousa, FC; de Vasconcelos, SM; Fernandes, ML; Rios, ER; Rocha, NF | 1 |
| Almeida, FR; Brandão, MS; Chaves, MH; Ferreira, EL; Lima, DF; Oliveira, JP; Pereira, SS | 1 |
| Kang, YJ; Kim, CH; Kim, SJ; Kim, SS; Lim, SM; Park, SH; Sim, YB; Suh, HW | 1 |
| Lazzari, P; Olimpieri, F; Pinna, GA; Reali, R; Tambaro, S; Volonterio, A; Zanda, M | 1 |
| Bhattacharya, SK; Gupta, LK; Gupta, R | 2 |
| Cervantes-Durán, C; Espinosa de los Monteros-Zuñiga, A; Godínez-Chaparro, B; Izquierdo, T; Lozada, MC | 1 |
| Andersen, ML; Carlini, EL; Gama, VS; Molska, GR; Paula-Freire, LI | 1 |
| Almeida, FR; Amaral, MP; Chaves, MH; Costa, DA; Figueiredo, KA; Júnior, FB; Oliveira, FA; Oliveira, IS; Oliveira, RC; Silva, FV | 1 |
| Haghparast, A; Pahlevani, P; Reisi, Z; Shamsizadeh, A | 1 |
| Ferdous, A; Irin, S; Moniruzzaman, M | 1 |
| Farshid, AA; Tamaddonfard, E; Yousofizadeh, S | 1 |
| Imam, MZ; Khatun, A; Rana, MS | 1 |
| Dabaghi, M; Erfanparast, A; Taati, M; Tamaddonfard, E | 1 |
| Coelho, IS; Junqueira, SC; Maldaner, G; Morel, AF; Pizzolatti, MG; Ruani, AP; Santos, AR; Simões, RR; Venzke, D; Zanchet, EM | 1 |
| Cheriyan, BV; Kadhirvelu, P; Nadipelly, J; Sayeli, V; Shanmugasundaram, J; Subramanian, V | 1 |
| Khoshdel, Z; Owji, AA; Takhshid, MA | 1 |
| Fanton, LE; Fischer, L; Macedo, CG; Tambeli, CH | 1 |
| Alboghobeish, S; Ghorbanzadeh, B; Mansouri, MT; Sahraei, H | 1 |
| Bhattacharjee, PS; Hossain, MS; Moniruzzaman, M | 1 |
| Chu, SS; Gu, XP; Li, L; Ma, ZL; Sun, Q; Yin, ZY | 1 |
| Choi, JG; Kang, DW; Kang, SY; Kim, HW; Lee, JH; Moon, JY; Park, JB; Ryu, Y | 1 |
| Erfanparast, A; Nemati, S; Tamaddonfard, E | 1 |
| Baeyens, JM; Cervero, F; Cobos, EJ; Coderre, TJ; Gonzalez-Cano, R; Lehmann, M; Pitcher, MH; Vincent, K | 1 |
| Fernandes, PD; Giorno, TBS; Moreira, IGDS; Rezende, CM | 1 |
| Micov, A; Pecikoza, U; Stepanović-Petrović, R; Tomić, M | 1 |
| Katsuyama, S; Komatsu, T; Kubota, A; Morinaga, O; Ogawa, K; Okamura, T; Sakurada, C; Sakurada, T; Tabata, K; Takano, F; Tsuzuki, M | 1 |
| Divac, N; Medić, B; Prostran, M; Savić Vujović, K; Srebro, D; Stojanović, R; Vasović, D; Vučković, S | 1 |
| Kang, Y; Kim, D; Lee, GJ; Lee, JY; Lee, PR; Oh, SB; Won, CH | 1 |
| Capim, SL; Côrtes, WDS; Gonçalves, GM; Laureano-Melo, R; Marinho, BG; Oliveira, PA; Vasconcellos, MLAA | 1 |
| Apryani, E; Deng, MY; Han, QQ; Shoaib, RM; Wang, YX; Wang, ZY; Wei, DQ; Zhao, MJ | 1 |
| Karaghiosoff, K; Kolb, C; Müller, HC; Philipp, M; Reiser, A; Schmidt, P | 1 |
| Ahmed, A; Ali, G; Ali, I; Ayaz, M; Khan, I; Khan, R; Mosa, OF; Murthy, HCA; Nawaz, A; Rahman, K | 1 |
| Bai, X; Guo, J; Huang, H; Ouyang, H; Wu, S; Zhang, K | 1 |
| Asgharieh-Ahari, M; Erfanparast, A; Soltanalinejad-Taghiabad, F; Tamaddonfard, E | 1 |
1 review(s) available for formaldehyde and naloxone
| Article | Year |
|---|---|
Opioid and catecholaminergic mechanisms of different types of analgesia.
Topics: Acetates; Acetic Acid; Acupuncture Therapy; Analgesia; Animals; Electric Stimulation; Electroshock; Endorphins; Formaldehyde; Haloperidol; Hot Temperature; Hydroxydopamines; Naloxone; Oxidopamine; Pain; Potassium Chloride; Propranolol; Rats; Reserpine; Sensory Thresholds | 1986 |
183 other study(ies) available for formaldehyde and naloxone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Naloxone reversal of morphine analgesia but failure to alter reactivity to pain in the formalin test.
Topics: Analgesia; Animals; Formaldehyde; Male; Morphine; Naloxone; Pain; Rats; Reaction Time; Receptors, Opioid; Time Factors | 1978 |
Stress-induced analgesia prevents the development of the tonic, late phase of pain produced by subcutaneous formalin.
Topics: Analgesia; Animals; Dizocilpine Maleate; Formaldehyde; Injections, Subcutaneous; Male; Mice; Naloxone; Pain; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stress, Physiological; Time Factors | 1992 |
[The characteristics of the opioid regulation of the afferent reactions of the stomach and duodenum to the early stages of their acute damage].
Topics: Afferent Pathways; Animals; Butorphanol; Cats; Cerebral Cortex; Duodenum; Electric Stimulation; Enkephalin, Leucine-2-Alanine; Evoked Potentials; Formaldehyde; Naloxone; Receptors, Opioid; Stomach; Thalamus; Time Factors | 1992 |
NMDA receptor antagonist MK-801 blocks non-opioid stress-induced analgesia in the formalin test.
Topics: Analgesia; Animals; Dizocilpine Maleate; Formaldehyde; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Pain; Receptors, N-Methyl-D-Aspartate; Sensation; Stress, Physiological | 1992 |
Analgesic and aversive effects of naloxone in BALB/c mice.
Topics: Analgesia; Animals; Choice Behavior; Dose-Response Relationship, Drug; Formaldehyde; Mice; Mice, Inbred BALB C; Naloxone; Naltrexone; Pain | 1992 |
The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Foot; Formaldehyde; Gene Expression Regulation; Injections, Intraventricular; Male; Molecular Sequence Data; Naloxone; Neurons; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Single-Blind Method; Spinal Cord | 1991 |
Time course of the alteration in dorsal horn substance P levels following formalin: blockade by naloxone.
Topics: Animals; Female; Foot; Formaldehyde; Injections; Naloxone; Rats; Rats, Inbred Strains; Sodium Chloride; Spinal Cord; Substance P; Time Factors | 1990 |
Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Naloxone; Nociceptors; Pain; Peptide Fragments; Reaction Time; Substance P; Urethane | 1991 |
Chromaffin allografts into arachnoid of spinal cord reduce basal pain responses in rats.
Topics: Adrenal Medulla; Animals; Arachnoid; Chromaffin System; Formaldehyde; Injections, Subcutaneous; Male; Naloxone; Pain Measurement; Palliative Care; Rats; Rats, Inbred Strains; Spinal Cord; Tissue Transplantation | 1991 |
Peripheral kappa-opioid modulation of the formalin response: an electrophysiological study in the rat.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Electric Stimulation; Electrophysiology; Evans Blue; Formaldehyde; Male; Naloxone; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Nociceptors; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa | 1990 |
Morphine hyperalgesic effects on the formalin test in domestic fowl (Gallus gallus).
Topics: Animals; Behavior, Animal; Chickens; Conditioning, Operant; Formaldehyde; Male; Morphine; Naloxone; Nociceptors; Pain; Pain Measurement; Reaction Time; Respiration | 1991 |
Naloxone blocks the formalin-induced increase of substance P in the dorsal horn.
Topics: Animals; Female; Formaldehyde; Immunoenzyme Techniques; Morphine; Naloxone; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Noradrenergic and opioidergic influences on the antinociceptive effect of clomipramine in the formalin test in rats.
Topics: Analgesics; Animals; Clomipramine; Endorphins; Female; Formaldehyde; Morphine; Naloxone; Norepinephrine; Pain Measurement; Phentolamine; Prazosin; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Cyclazocine; Ethylketocyclazocine; Formaldehyde; Injections, Intraventricular; Male; Naloxone; Pain; Rats | 1988 |
A dose-ratio comparison of mu and kappa agonists in formalin and thermal pain.
Topics: Analgesia; Animals; Benzomorphans; Cyclazocine; Dose-Response Relationship, Drug; Ethylketocyclazocine; Fentanyl; Formaldehyde; Hot Temperature; Male; Naloxone; Pain; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil | 1986 |
Systemic naloxone does not affect pain-related behaviour in the formalin test in rat.
Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Grooming; Male; Motor Activity; Naloxone; Nociceptors; Rats; Rats, Inbred Strains | 1988 |
Systemic administration of naloxone produces analgesia in BALB/c mice in the formalin pain test.
Topics: Analgesia; Animals; Female; Formaldehyde; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Naloxone; Pain Measurement | 1988 |
Involvement of medullary opioid-peptidergic and spinal noradrenergic systems in the regulation of formalin-induced persistent pain.
Topics: Animals; Endorphins; Formaldehyde; Injections, Spinal; Leucine; Male; Medulla Oblongata; Naloxone; Norepinephrine; Pain; Rats; Rats, Inbred Strains; Spinal Cord; Thiorphan; Time Factors; Tiopronin | 1986 |
Effect of neurotropin on hyperalgesia induced by prostaglandin E2, naloxone, melatonin and dark condition in mice.
Topics: Analgesics; Animals; Aspirin; Darkness; Dinoprostone; Formaldehyde; Male; Melatonin; Mice; Naloxone; Pain; Polysaccharides; Prostaglandins E | 1987 |
Conditioned fear-induced opiate analgesia: a competing motivational state theory of stress analgesia.
Topics: Analgesia; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Endorphins; Fear; Formaldehyde; Models, Biological; Motor Activity; Naloxone; Naltrexone; Nociceptors; Sensory Thresholds; Shock; Stress, Physiological | 1986 |
Effects of morphine on two types of nucleus raphe dorsalis neurons in awake cats.
Topics: Action Potentials; Animals; Cats; Formaldehyde; Morphine; Naloxone; Neurons; Pain; Raphe Nuclei; Wakefulness | 1987 |
The stress of a novel environment reduces formalin pain: possible role of serotonin.
Topics: Animals; Environment; Formaldehyde; Habituation, Psychophysiologic; Methysergide; Naloxone; Pain; Rats; Serotonin; Stress, Psychological; Valine | 1986 |
Studies on the physical dependence liability of analgesics. 1. Electron microscopic studies on the ultra-structural transformation of mitochondria in the cells of zona fasciculata of the adrenal cortex in morphine addicted rats.
Topics: Adrenal Glands; Animals; Cold Temperature; Dactinomycin; Formaldehyde; Humans; Levallorphan; Male; Microscopy, Electron; Mitochondria; Mitochondria, Liver; Morphine Dependence; Naloxone; Pituitary Gland; Rats; Substance Withdrawal Syndrome | 1973 |
Shock-induced analgesia on the formalin test: effects of shock severity, naloxone, hypophysectomy, and associative variables.
Topics: Animals; Arousal; Association Learning; beta-Endorphin; Conditioning, Classical; Electroshock; Endorphins; Female; Formaldehyde; Grooming; Naloxone; Nociceptors; Pituitary Gland; Rats; Social Environment | 1984 |
Examination of tonic nociceptive behavior using a method of substance P-receptor desensitization in the dorsal horn.
Topics: Animals; Formaldehyde; Injections, Spinal; Male; Morphine; Naloxone; Nociceptors; Pain Measurement; Rats; Rats, Wistar; Receptors, Neurokinin-1; Reflex; Spinal Cord; Stereotyped Behavior; Substance P; Uric Acid | 1994 |
Inflammation of the colonic wall induced by formalin as a model of acute visceral pain.
Topics: Acute Disease; Animals; Colitis; Disease Models, Animal; Female; Formaldehyde; Morphine; Naloxone; Pain; Pain Measurement; Palliative Care; Rats; Rats, Sprague-Dawley; Sodium Chloride; Viscera | 1994 |
Antinociception induced by CP 96,345, a non-peptide NK-1 receptor antagonist, in the mouse formalin and capsaicin tests.
Topics: Analgesics; Animals; Biphenyl Compounds; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Hypnotics and Sedatives; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Naloxone; Pain; Pain Measurement; Postural Balance; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1993 |
Antinociceptive effects in the formalin and capsaicin tests after intrathecal administration of substance P analogues in mice.
Topics: Analgesics; Animals; Capsaicin; Drug Interactions; Formaldehyde; Injections, Spinal; Male; Mice; Naloxone; Pain; Substance P | 1993 |
A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test.
Topics: Analgesics; Animals; Disulfides; Enkephalins; Formaldehyde; Indoles; Male; Meglumine; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Phenylalanine; Receptors, Cholecystokinin; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Antinociceptive effect of morphine microinjections into the spinal trigeminal subnucleus oralis.
Topics: Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Microinjections; Morphine; Naloxone; Pain; Rats; Rats, Sprague-Dawley; Trigeminal Nucleus, Spinal | 1995 |
The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats.
Topics: Animals; Behavior, Animal; Citrulline; Dinoprostone; Excitatory Amino Acids; Formaldehyde; Male; Microdialysis; Morphine; Motor Activity; Naloxone; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1995 |
Participation of opioid and monoaminergic mechanisms on the antinociceptive effect induced by tricyclic antidepressants in two behavioural pain tests in mice.
Topics: alpha-Methyltyrosine; Analgesics; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Biogenic Monoamines; Electric Stimulation; Endorphins; Fenclonine; Formaldehyde; Male; Methyltyrosines; Mice; Mice, Inbred Strains; Naloxone; Pain Measurement; Tail; Tyrosine 3-Monooxygenase | 1994 |
Changes in hypothalamic met-enkephalin levels of rats induced by painful stimulation and morphine treatment.
Topics: Animals; Enkephalin, Methionine; Formaldehyde; Hypothalamus; Male; Morphine; Naloxone; Pain; Rats; Rats, Wistar; Stimulation, Chemical | 1993 |
Effects of midazolam and naloxone in rats tested for sensitivity/reactivity to formalin pain in a familiar, novel or aversively conditioned environment.
Topics: Analgesia; Animals; Conditioning, Operant; Conditioning, Psychological; Environment; Extinction, Psychological; Flumazenil; Formaldehyde; Male; Midazolam; Naloxone; Pain Measurement; Rats; Rats, Wistar; Reaction Time; Reinforcement, Psychology | 1994 |
Morphine dependence with or without tolerance in formalin-treated mice: further evidence for the dissociation.
Topics: Analgesia; Animals; Anxiety; Disease Models, Animal; Drug Tolerance; Formaldehyde; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Naloxone; Pain; Pain Threshold | 1994 |
Systemic opioids do not suppress spinal sensitization after subcutaneous formalin in rats.
Topics: Alfentanil; Animals; Drug Administration Schedule; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Subcutaneous; Isoflurane; Male; Morphine; Naloxone; Pain; Rats; Rats, Sprague-Dawley; Spine; Time Factors | 1994 |
Taurine modulates chemical nociception in mice.
Topics: Acetates; Animals; Formaldehyde; Male; Mice; Naloxone; Nociceptors; Pain; Pain Measurement; Reaction Time; Taurine | 1993 |
Formalin-induced pain antagonizes the development of opiate dependence in the rat.
Topics: Animals; Behavior, Animal; Blepharoptosis; Diarrhea; Formaldehyde; Male; Morphine Dependence; Naloxone; Pain; Rats; Substance Withdrawal Syndrome | 1993 |
Naloxone causes apparent antinociception and pronociception simultaneously in the rat paw formalin test.
Topics: Animals; Behavior, Animal; Buprenorphine; Dose-Response Relationship, Drug; Formaldehyde; Injections, Subcutaneous; Male; Morphine; Naloxone; Pain; Rats; Rats, Sprague-Dawley | 1993 |
Effects of codeine, naproxen and dexamethasone on formalin-induced pain in the naked mole-rat.
Topics: Animals; Behavior, Animal; Codeine; Dexamethasone; Dose-Response Relationship, Drug; Formaldehyde; Injections, Intraperitoneal; Injections, Subcutaneous; Muscle Rigidity; Naloxone; Naproxen; Pain; Rodentia | 1993 |
Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: demonstration of an opioid kappa and delta inhibitory tone.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Formaldehyde; Immune Sera; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1996 |
Differential contribution of descending controls to the antinociceptive actions of kappa and mu opioids: an analysis of formalin-evoked C-fos expression.
Topics: Analgesics, Opioid; Animals; Benzofurans; Dose-Response Relationship, Drug; Formaldehyde; Male; Naloxone; Proto-Oncogene Proteins c-fos; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spinal Cord | 1996 |
The peripheral antinociceptive effect of morphine in a rat model of facial pain.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Facial Pain; Formaldehyde; Grooming; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Rats; Rats, Sprague-Dawley; Vibrissae | 1996 |
Differential sensitivity of mice bred for stress-induced analgesia to morphine and ACEA-1011 in the formalin test.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Quinoxalines; Stress, Psychological; Swimming | 1996 |
Opioid antagonist profile of SC nor-binaltorphimine in the formalin paw assay.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes | 1996 |
Early nociceptive events influence the temporal profile, but not the magnitude, of the tonic response to subcutaneous formalin: effects with remifentanil.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthesia, Inhalation; Animals; Blood Pressure; Formaldehyde; Halothane; Heart Rate; Injections, Intravenous; Male; Naloxone; Pain; Piperidines; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Remifentanil; Time Factors | 1997 |
Naloxone-reversible antinociception by paracetamol in the rat.
Topics: Acetaminophen; Animals; Cerebral Cortex; Formaldehyde; Hot Temperature; Ketanserin; Kinetics; Male; Morphine; Motor Activity; Naloxone; Pain; Pons; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Stereotyped Behavior | 1997 |
Influence of low and high doses of naloxone on tonic pain and motor activity in rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Formaldehyde; Male; Motor Activity; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Rats; Rats, Wistar | 1996 |
Continuous intravenous infusion of naloxone does not change behavioral, cardiovascular, or inflammatory responses to subcutaneous formalin in the rat.
Topics: Animals; Behavior, Animal; Blood Pressure; Formaldehyde; Heart Rate; Hemodynamics; Inflammation; Infusions, Intravenous; Injections, Subcutaneous; Male; Naloxone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley | 1997 |
Serotonin and opiate involvement in the antinociceptive effect of acetylsalicylic acid.
Topics: Analgesics, Non-Narcotic; Animals; Aspirin; Behavior, Animal; Brain Chemistry; Endorphins; Formaldehyde; Male; Membranes; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin | 1997 |
Inhalation anesthetics suppress the expression of c-Fos protein evoked by noxious somatic stimulation in the deeper layer of the spinal cord in the rat.
Topics: Analgesia; Anesthetics, Inhalation; Animals; Formaldehyde; Halothane; Hindlimb; Male; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Nitrous Oxide; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Spinal Cord | 1997 |
Insulin attenuates formalin-induced nociceptive response in mice through a mechanism that is deranged by diabetes mellitus.
Topics: Analgesics; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Formaldehyde; Indoles; Insulin; Ketanserin; Male; Mice; Mice, Inbred C57BL; Naloxone; Pindolol; Streptozocin; Sulpiride; Tropisetron | 1997 |
Attenuation of formalin pain responses in the rat by adrenal medullary transplants in the spinal subarachnoid space.
Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Animals; Foot; Formaldehyde; Injections; Male; Naloxone; Narcotic Antagonists; Pain; Palliative Care; Phentolamine; Rats; Rats, Sprague-Dawley; Spinal Cord; Subarachnoid Space | 1997 |
Spinally delivered nociceptin/orphanin FQ reduces flinching behaviour in the rat formalin test.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Male; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Time Factors | 1997 |
d-Methadone is antinociceptive in the rat formalin test.
Topics: Analgesics, Opioid; Animals; Formaldehyde; Male; Methadone; N-Methylaspartate; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1997 |
Ruthenium red and capsazepine antinociceptive effect in formalin and capsaicin models of pain in mice.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Formaldehyde; Injections, Intradermal; Injections, Intraventricular; Male; Mice; Naloxone; Pain; Ruthenium Red | 1997 |
Morphine analgesia in the formalin test: reversal by microinjection of quaternary naloxone into the posterior hypothalamic area or periaqueductal gray.
Topics: Analgesics, Opioid; Animals; Formaldehyde; Hypothalamus, Posterior; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Periaqueductal Gray; Rats | 1998 |
Morphine reversed formalin-induced CA1 pyramidal cell suppression via an effect on septohippocampal neural processing.
Topics: Action Potentials; Animals; Disinfectants; Formaldehyde; Hippocampus; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Pain; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Septal Nuclei; Theta Rhythm | 1999 |
[Effect of corticotropin on formalin-evoked c-fos expression of spinal cord and receptors analysis in rat].
Topics: Adrenalectomy; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium Channel Blockers; Formaldehyde; Naloxone; Narcotic Antagonists; Phentolamine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Opioid; Spinal Cord; Verapamil | 1998 |
Pre- versus postformalin effects of ketamine or large-dose alfentanil in the rat: discordance between pain behavior and spinal Fos-like immunoreactivity.
Topics: Alfentanil; Analgesics, Opioid; Animals; Formaldehyde; Ketamine; Male; Naloxone; Pain; Proto-Oncogene Proteins c-fos; Rats; Rats, Long-Evans; Spinal Cord | 1999 |
Effects of forced walking stress on formalin-induced paw licking in mice.
Topics: Analgesia; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Neuroprotective Agents; Pain; Pain Measurement; Physical Exertion; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Walking | 1999 |
Antinociceptive properties of fenfluramine, a serotonin reuptake inhibitor, in a rat model of neuropathy.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Fenfluramine; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Ligation; Male; Metergoline; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Spinal Nerves; Synaptic Transmission | 1999 |
Effect of intrathecal nocistatin on the formalin-induced pain in mice versus that of nociceptin/orphanin FQ.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Foot; Formaldehyde; Hindlimb; Injections, Spinal; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Spinal Cord | 2000 |
Antinociceptive effects of the tubercles of Anredera leptostachys.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Caribbean Region; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Escape Reaction; Exploratory Behavior; Formaldehyde; Hot Temperature; Male; Medicine, Traditional; Methanol; Mice; Morphine; Muscle Relaxation; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Plant Extracts; Solubility; Time Factors | 1999 |
Role of gonadal hormones in formalin-induced pain responses of male rats: modulation by estradiol and naloxone administration.
Topics: Animals; Behavior, Animal; Corticosterone; Disinfectants; Estradiol; Formaldehyde; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Naloxone; Narcotic Antagonists; Orchiectomy; Pain; Pituitary-Adrenal System; Rats; Rats, Wistar; Testosterone | 2000 |
Involvement of M3 muscarinic receptors of the spinal cord in formalin-induced nociception in mice.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Agents; Cholinesterase Inhibitors; Formaldehyde; Hemicholinium 3; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Neostigmine; Nociceptors; Pain; Pain Measurement; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; Spinal Cord | 2000 |
Antinociceptive effect of the essential oil from Cymbopogon citratus in mice.
Topics: Acetates; Analgesics; Animals; Behavior, Animal; Caribbean Region; Chromatography, Gas; Formaldehyde; Male; Mass Spectrometry; Mice; Naloxone; Narcotic Antagonists; Oils, Volatile; Pain Measurement; Plant Leaves; Plants, Medicinal; Poaceae; Reaction Time | 2000 |
Sildenafil produces antinociception and increases morphine antinociception in the formalin test.
Topics: Analgesics; Animals; Cyclic GMP; Drug Synergism; Female; Formaldehyde; Guanylate Cyclase; Morphine; Naloxone; NG-Nitroarginine Methyl Ester; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones | 2000 |
Differential involvement of opioid receptors in stress-induced antinociception caused by repeated exposure to forced walking stress in mice.
Topics: Animals; Formaldehyde; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid; Stress, Physiological; Walking | 2000 |
Saccharin effects on morphine-induced antinociception in the mouse formalin test.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Saccharin; Sweetening Agents | 2000 |
Pharmacological validation of an automated method of pain scoring in the formalin test in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Automation; Behavior, Animal; Drug Interactions; Formaldehyde; Image Processing, Computer-Assisted; Male; Morphine; Naloxone; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Serotonin | 1999 |
Peripheral antinociceptive interaction of dipyrone and morphine in the formalin test.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar | 2000 |
Effect of imipramine on tolerance to morphine antinociception in the formalin test.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Disinfectants; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Formaldehyde; Imipramine; Injections, Intraperitoneal; Male; Mice; Morphine; Naloxone; Pain | 2000 |
Effect of chronic and acute administration of fluoxetine and its additive effect with morphine on the behavioural response in the formalin test in rats.
Topics: 5,7-Dihydroxytryptamine; Analgesics, Opioid; Animals; Drug Synergism; Fluoxetine; Formaldehyde; Injections, Intraperitoneal; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Time Factors | 2001 |
Altered neuroadaptation in opiate dependence and neurogenic inflammatory nociception in alpha CGRP-deficient mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Carrageenan; Fixatives; Formaldehyde; Ganglionic Stimulants; Inflammation; Magnesium Sulfate; Mice; Mice, Transgenic; Morphine; Naloxone; Narcotic Antagonists; Nicotine; Opioid-Related Disorders; Pain; Substance Withdrawal Syndrome | 2001 |
3-Methyl-5-hydroxy-5-trichloromethyl-1H-1-pyrazolcarboxyamide induces antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Formaldehyde; Immersion; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Postural Balance; Pyrazoles; Rats; Rats, Wistar | 2001 |
Subcutaneous formalin enhances outflow of met-enkephalin- and cholecystokinin-like materials in the rat nucleus accumbens.
Topics: Animals; Cholecystokinin; Chromatography, High Pressure Liquid; Disinfectants; Enkephalin, Methionine; Formaldehyde; Male; Microdialysis; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 2001 |
Tolerance to analgesia and dependence liability by topical application of dihydroetorphine to hairless rats.
Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Formaldehyde; Inflammation; Infusions, Intravenous; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Nude; Substance-Related Disorders; Time Factors; Weight Loss | 2001 |
Opiate-like substances mediate norepinephrine-induced but not serotonin-induced antinociception at spinal level: reevaluation by an electrophysiological model of formalin test in rats.
Topics: Animals; Drug Interactions; Electrophysiology; Female; Formaldehyde; Male; Naloxone; Nociceptors; Norepinephrine; Pain Measurement; Rats; Rats, Wistar; Serotonin | 2001 |
B vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice.
Topics: Acetic Acid; Animals; Constriction; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Hindlimb; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Motor Activity; Naloxone; Nociceptors; Pain; Pain Measurement; Pyridoxine; Riboflavin; Thiamine; Vitamin B 12; Vitamin B Complex | 2001 |
Cervicomedullary intrathecal injection of morphine produces antinociception in the orofacial formalin test in the rat.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Blood Gas Analysis; Face; Formaldehyde; Hemodynamics; Injections; Injections, Spinal; Male; Morphine; Motor Activity; Mouth; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar | 2001 |
Analgesic effect of B vitamins in formalin-induced inflammatory pain.
Topics: Animals; Behavior, Animal; Female; Formaldehyde; Inflammation; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Wistar; Vitamin B Complex | 2001 |
Comparison of the peripheral and central effects of the opioid agonists loperamide and morphine in the formalin test in rats.
Topics: Analgesics, Opioid; Animals; Antidiarrheals; Cisterna Magna; Dose-Response Relationship, Drug; Formaldehyde; Injections; Injections, Subcutaneous; Loperamide; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2002 |
Nociceptive behaviour induced by dental application of irritants to rat incisors: a new model for tooth inflammatory pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Capsaicin; Crowns; Cyclooxygenase Inhibitors; Dental Pulp Cavity; Disease Models, Animal; Drug Interactions; Female; Formaldehyde; Gingiva; Inflammation; Male; Meloxicam; Morphine; Naloxone; Narcotic Antagonists; Nerve Fibers; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Thiazines; Thiazoles; Toothache | 2002 |
Age-related differences in forced walking stress-induced analgesia in mice.
Topics: Aging; Analgesia; Animals; Excitatory Amino Acid Antagonists; Formaldehyde; Isoquinolines; Male; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Walking | 2001 |
Sevoflurane suppresses noxious stimulus-evoked expression of Fos-like immunoreactivity in the rat spinal cord via activation of endogenous opioid systems.
Topics: Analgesics; Anesthetics, Inhalation; Animals; Formaldehyde; Male; Methyl Ethers; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Sevoflurane; Spinal Cord | 2002 |
Studies on new cyclic imides obtained from aminophenazone with analgesic properties. Potent effects of a 3,4-dichloromaleimide derivative.
Topics: Acetic Acid; Aminopyrine; Analgesics, Non-Narcotic; Animals; Capsaicin; Formaldehyde; Imides; Indicators and Reagents; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Peritonitis; Reaction Time; Structure-Activity Relationship | 2002 |
Mechanisms of analgesic action of B vitamins in formalin-induced inflammatory pain.
Topics: Analgesics; Animals; Behavior, Animal; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Inflammation; Methiothepin; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain Measurement; Potassium Channel Blockers; Rats; Rats, Wistar; Serotonin Antagonists; Vitamin B Complex | 2002 |
The role of contextual cues on counterirritation in the development process of analgesic tolerance to morphine.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Cues; Dose-Response Relationship, Drug; Drug Tolerance; Extinction, Psychological; Formaldehyde; Hot Temperature; Irritants; Male; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time | 2002 |
[MK-801 suppresses dynorphin A (1-17)-induced facilitation of nociceptive responses to formalin in rats].
Topics: Animals; Dizocilpine Maleate; Dynorphins; Formaldehyde; Injections, Spinal; Naloxone; Nociceptors; Pain; Rats; Receptors, N-Methyl-D-Aspartate | 2003 |
Adrenalectomy affects pain behavior of rats after formalin injection.
Topics: Adrenalectomy; Animals; Behavior, Animal; beta-Endorphin; Corticosterone; Formaldehyde; Injections, Intraperitoneal; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pituitary Hormones; Prolactin; Rats; Rats, Sprague-Dawley; Thyrotropin | 2004 |
Role of micro-opioid receptors in formalin-induced pain behavior in mice.
Topics: Animals; Behavior, Animal; Formaldehyde; Immunohistochemistry; Male; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Receptors, Opioid, mu; Spinal Cord | 2003 |
Formalin assay parameters differ in confirming the antinociceptive mechanism of domperidone in mice.
Topics: Analgesics; Animals; Disinfectants; Domperidone; Dopamine Antagonists; Drug Combinations; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Pain Measurement; Time Factors | 2004 |
Intracisternal NMDA produces analgesia in the orofacial formalin test of freely moving rats.
Topics: Analgesics; Animals; Behavior, Animal; Cisterna Magna; Excitatory Amino Acid Agonists; Face; Formaldehyde; Injections; Male; Microinjections; N-Methylaspartate; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Vibrissae | 2004 |
Protein kinase C is partly involved in c-fos protein expression of nocuously-activated neurons but may not in concomitant modulatory action through opioid receptors at the spinal level in rats.
Topics: Animals; Formaldehyde; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Spinal Cord | 2004 |
Effects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn.
Topics: Animals; Cattle; Cell Count; Drug Interactions; Enkephalin, Methionine; Enkephalins; Formaldehyde; Gene Expression Regulation; Hot Temperature; Immunohistochemistry; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Pain; Pain Measurement; Physical Stimulation; Protein Precursors; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord | 2004 |
Evidence of self-synergism in the antinociceptive effect of tramadol in rats.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Tramadol | 2004 |
Functional magnetic resonance imaging studies of opioid receptor-mediated modulation of noxious-evoked BOLD contrast in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Brain; Brain Mapping; Drug Interactions; Formaldehyde; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid | 2005 |
Antinociceptive activity of Calotropis procera latex in mice.
Topics: Acetic Acid; Analgesics; Animals; Calotropis; Dose-Response Relationship, Drug; Formaldehyde; Hot Temperature; Latex; Male; Mice; Naloxone; Narcotic Antagonists; Pain Measurement; Plant Proteins; Reaction Time | 2005 |
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms | 2005 |
Endogenous opioid mechanisms partially mediate P2X3/P2X2/3-related antinociception in rat models of inflammatory and chemogenic pain but not neuropathic pain.
Topics: Analgesia; Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Endorphins; Formaldehyde; Freund's Adjuvant; Inflammation; Injections, Spinal; Ligation; Male; Naloxone; Narcotic Antagonists; Pain; Peripheral Nervous System Diseases; Phenols; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Suramin | 2005 |
Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice.
Topics: Analgesics; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Formaldehyde; Haloperidol; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Time Factors | 2005 |
Evaluation of the analgesic effect of Echium amoenum Fisch & C.A. Mey. extract in mice: possible mechanism involved.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Echium; Flowers; Formaldehyde; Hot Temperature; Injections, Intraperitoneal; Iran; Male; Medicine, Arabic; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Plant Extracts; Receptors, Opioid; Time Factors | 2006 |
The effects of restraint stress on nociceptive responses induced by formalin injected in rat's TMJ.
Topics: Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Behavior, Animal; Corticosterone; Formaldehyde; Injections; Male; Morphine; Naloxone; Narcotic Antagonists; Nociceptors; Pain Measurement; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Temporomandibular Joint | 2005 |
Cross-tolerance between antinociception induced by swim-stress and morphine in formalin test.
Topics: Analgesia; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Formaldehyde; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Stress, Psychological; Swimming | 2005 |
Role of kappa- and delta-opioid receptors in the antinociceptive effect of oxytocin in formalin-induced pain response in mice.
Topics: Analgesics; Animals; Behavior; Calcium Channel Blockers; Dose-Response Relationship, Drug; Formaldehyde; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Nimodipine; Oxytocin; Pain; Random Allocation; Receptors, Opioid, delta; Receptors, Opioid, kappa | 2006 |
Study on the antinociceptive effects of Thymus broussonetii Boiss extracts in mice and rats.
Topics: Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Plant Bark; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Thymus Plant | 2006 |
Is protein kinase C (PKC) involved in nociception?
Topics: Alkaloids; Animals; Behavior, Animal; Benzophenanthridines; Enzyme Inhibitors; Formaldehyde; Functional Laterality; Gene Expression; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Nociceptors; Pain; Phenanthridines; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes | 2006 |
Antinociceptive action of (+/-)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid in mice.
Topics: Acetic Acid; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Formaldehyde; Formates; Hot Temperature; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Pain Measurement; Pyrans; Reaction Time; Receptors, Opioid; Spine | 2006 |
Morphine-induced antinociception in the formalin test: sensitization and interactions with D1 and D2 dopamine receptors and nitric oxide agents.
Topics: Analgesics, Opioid; Animals; Arginine; Benzazepines; Dopamine Antagonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Formaldehyde; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain Measurement; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride | 2007 |
Antinociceptive activity of Syzygium jambos leaves extract on rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Formaldehyde; Hand Strength; Hot Temperature; Male; Morphine; Muscle, Skeletal; Naloxone; Narcotic Antagonists; Pain Measurement; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Reaction Time; Syzygium | 2007 |
Pharmacological analysis of paregoric elixir and its constituents: in vitro and in vivo studies.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Drug Tolerance; Electric Stimulation; Female; Formaldehyde; Gastrointestinal Transit; Lethal Dose 50; Male; Mice; Morphine; Motor Activity; Muscle Contraction; Muscle, Smooth; Naloxone; Narcotic Antagonists; Opium; Pain Measurement; Papaverine; Parasympatholytics; Spectrophotometry, Ultraviolet | 2007 |
15d-prostaglandin J2 inhibits inflammatory hypernociception: involvement of peripheral opioid receptor.
Topics: Analgesics; Animals; Carrageenan; Cytokines; Formaldehyde; Hyperalgesia; Inflammation; Macrophages; Male; Naloxone; Narcotic Antagonists; Pain; PPAR gamma; Prostaglandin D2; Rats; Rats, Wistar; Receptors, Opioid; Skin; Tumor Necrosis Factor-alpha | 2008 |
Multivariate calibration applied to the time-resolved chemiluminescence for the simultaneous determination of morphine and its antagonist naloxone.
Topics: Acids; Calibration; Formaldehyde; Luminescent Measurements; Molecular Structure; Morphine; Naloxone; Potassium; Temperature; Time Factors | 2007 |
Simultaneous stopped-flow determination of morphine and naloxone by time-resolved chemiluminescence.
Topics: Calibration; Flow Injection Analysis; Formaldehyde; Luminescent Measurements; Morphine; Naloxone; Potassium Permanganate; Sulfuric Acids; Time | 2008 |
Antinociceptive effect of hydroxydihydrocarvone.
Topics: Analgesics; Animals; Catalepsy; Dose-Response Relationship, Drug; Formaldehyde; Hot Temperature; Male; Mice; Monoterpenes; Naloxone; Narcotic Antagonists; Pain Measurement; Reaction Time | 2008 |
Antinociceptive activity of (-)-carvone: evidence of association with decreased peripheral nerve excitability.
Topics: Acetates; Action Potentials; Analgesics; Analgesics, Opioid; Animals; Cyclohexane Monoterpenes; Diazepam; Electrophysiology; Formaldehyde; Hypnotics and Sedatives; Male; Mice; Monoterpenes; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Peripheral Nerves; Postural Balance; Stereoisomerism; Sucrose | 2008 |
Evaluation of the antinociceptive activity of Ficus deltoidea aqueous extract.
Topics: Acetic Acid; Analgesics; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Ficus; Formaldehyde; Hot Temperature; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley | 2008 |
Activation of micro, delta or kappa opioid receptors by DAMGO, DPDPE, U-50488 or U-69593 respectively causes antinociception in the formalin test in the naked mole-rat (Heterocephalus glaber).
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzeneacetamides; Data Interpretation, Statistical; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Formaldehyde; Injections, Intraperitoneal; Male; Mole Rats; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2009 |
Spinal antinociceptive action of loperamide is mediated by opioid receptors in the formalin test in rats.
Topics: Analgesics; Animals; Behavior, Animal; Formaldehyde; Injections, Spinal; Loperamide; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord | 2008 |
Additive antinociception between intrathecal sildenafil and morphine in the rat formalin test.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Management; Pain Measurement; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Time Factors | 2008 |
Antinociceptive effects of hydroalcoholic extract of Thymus vulgaris.
Topics: Analgesics; Animals; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Plant Extracts; Stress, Psychological; Thymus Plant | 2009 |
Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice.
Topics: Acetic Acid; Analgesics; Animals; Arginine; Atropine; Cinnamates; Depsides; Dose-Response Relationship, Drug; Female; Formaldehyde; Glutamic Acid; Male; Mecamylamine; Melissa; Mice; Motor Activity; Naloxone; Nitric Oxide; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, Muscarinic; Receptors, Nicotinic; Rosmarinic Acid | 2009 |
Antinociceptive activity of Amaranthus spinosus in experimental animals.
Topics: Acetic Acid; Amaranthus; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Formaldehyde; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts | 2009 |
Antinociceptive effects of (O-methyl)-N-benzoyl tyramine (riparin I) from Aniba riparia (Nees) Mez (Lauraceae) in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Formaldehyde; Hot Temperature; Injections, Intraperitoneal; Lauraceae; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Reaction Time; Time Factors; Tyramine | 2009 |
The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating mu-opioid receptors.
Topics: Analgesics; Animals; Bacterial Toxins; Cell Line, Tumor; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli Proteins; Formaldehyde; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naloxone; Narcotic Antagonists; Neuroblastoma; NF-kappa B; p21-Activated Kinases; Pain; Pain Measurement; rac GTP-Binding Proteins; Receptors, Opioid, mu; rho GTP-Binding Proteins; Signal Transduction; Time Factors; Transfection; Up-Regulation | 2009 |
Formalin-induced differential activation of nucleus cuneiformis neurons in the rat: an electrophysiological study.
Topics: Action Potentials; Analgesics, Opioid; Animals; Behavior, Animal; Central Nervous System Agents; Formaldehyde; Male; Mesencephalon; Microelectrodes; Morphine; Naloxone; Narcotic Antagonists; Neurons; Pain; Pain Measurement; Rats; Rats, Inbred Strains | 2010 |
Antinociceptive activity of the essential oil of Zingiber zerumbet.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Oils, Volatile; Pain; Plant Extracts; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Rhizome; Zingiberaceae | 2010 |
Evaluation of anti-inflammatory and analgesic activity of a novel rigid 3, 4-dihydroxy chalcone in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Aspirin; Chalcone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Formaldehyde; Hot Temperature; Inflammation; Male; Mice; Molecular Structure; Morphine; Naloxone; Narcotic Antagonists; Pain; Pain Measurement | 2009 |
Contribution of endogenous opioids to gonadal hormones-induced temporomandibular joint antinociception.
Topics: Analgesia; Analysis of Variance; Androgens; Animals; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrous Cycle; Female; Formaldehyde; Male; Naloxone; Narcotic Antagonists; Opioid Peptides; Ovariectomy; Pain; Pain Measurement; Progesterone; Progestins; Rats; Rats, Wistar; Temporomandibular Joint; Testosterone Propionate | 2009 |
Antinociceptive activity of aqueous extract of Bowdichia virgilioides in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Fabaceae; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems | 2010 |
DNIC-mediated analgesia produced by a supramaximal electrical or a high-dose formalin conditioning stimulus: roles of opioid and alpha2-adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Analgesia; Analysis of Variance; Animals; Area Under Curve; Conditioning, Psychological; Electric Stimulation; Formaldehyde; Immunohistochemistry; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Pain; Rats; Rats, Sprague-Dawley; Yohimbine | 2010 |
In vivo analgesic effect of aqueous extract of Tamarindus indica L. fruits.
Topics: Analgesics; Analysis of Variance; Animals; Fixatives; Formaldehyde; Fruit; Male; Mice; Morphine; Naloxone; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Tamarindus | 2010 |
Antinociceptive effects of docosahexaenoic acid against various pain stimuli in mice.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Formaldehyde; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Tail | 2010 |
Remarkably long-lasting tachyphylaxis of pain responses to ET-1: evidence against central nervous system involvement.
Topics: Anesthetics; Animals; Central Nervous System; Endothelin A Receptor Antagonists; Endothelin-1; Foot; Formaldehyde; Hindlimb; Hyperalgesia; Male; Naloxone; Pain; Pain Measurement; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tachyphylaxis; Time Factors; Touch | 2010 |
A comparative chemical and pharmacological study of standardized extracts and vanillic acid from wild and cultivated Amburana cearensis A.C. Smith.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carrageenan; Dextrans; Edema; Fabaceae; Formaldehyde; Leukocytes; Male; Mice; Naloxone; Pain; Peritoneum; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Vanillic Acid | 2011 |
Tuberoinfundibular peptide of 39 residues (TIP39) signaling modulates acute and tonic nociception.
Topics: Amidohydrolases; Animals; Cannabinoid Receptor Modulators; Formaldehyde; In Situ Hybridization; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Knockout; Naloxone; Narcotic Antagonists; Neuropeptides; Nociceptors; Pain; Pain Measurement; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Parathyroid Hormone, Type 2; Rimonabant; RNA, Messenger; Signal Transduction; Stress, Psychological; Synapses; Vesicular Glutamate Transport Protein 2 | 2010 |
Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eriobotrya; Female; Formaldehyde; Hot Temperature; Indomethacin; Inflammation Mediators; Interferon-gamma; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, Opioid | 2011 |
Antinociceptive effect of extract of Emilia sonchifolia in mice.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Asteraceae; Behavior, Animal; Brazil; Disease Models, Animal; Formaldehyde; Hot Temperature; Male; Medicine, Traditional; Mice; Morphine; Naloxone; Pain; Phenols; Phytotherapy; Plant Components, Aerial; Plant Extracts | 2011 |
Synergistic interaction between intrathecal ginsenosides and morphine on formalin-induced nociception in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fixatives; Formaldehyde; Gene Expression Regulation; Ginsenosides; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reflex; Somatostatin | 2011 |
Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Hippocampus; Histamine; Male; Morphine; Naloxone; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2 | 2011 |
Antinociceptive and hypnotic properties of Celastrus orbiculatus.
Topics: Acetic Acid; Animals; Celastrus; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Hypnotics and Sedatives; Indomethacin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Phenobarbital; Plant Extracts; Plants, Medicinal; Reaction Time; Sleep; Time Factors; Tramadol | 2011 |
Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin.
Topics: Aconitine; Adjuvants, Anesthesia; Analgesics; Animals; Antihypertensive Agents; Atropine; Cobra Neurotoxin Proteins; Drug Interactions; Formaldehyde; Male; Mecamylamine; Naloxone; Narcotic Antagonists; Nicotinic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic | 2011 |
Anti-inflammatory and antinociceptive effects of the stem bark of Byrsonima intermedia A. Juss.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Carrageenan; Chromatography, High Pressure Liquid; Cotton Fiber; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Flavonoids; Formaldehyde; Granuloma, Foreign-Body; Hot Temperature; Lipopolysaccharides; Male; Malpighiaceae; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Peritonitis; Phenols; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Rats; Rats, Wistar; Time Factors | 2011 |
Evaluation of antinociceptive effects of Crassocephalum bauchiense Hutch (Asteraceae) leaf extract in rodents.
Topics: Acetic Acid; Administration, Oral; Alkaloids; Analgesics; Analgesics, Opioid; Animals; Asteraceae; Behavior, Animal; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Glutamic Acid; Hot Temperature; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Solvents; Time Factors; Water | 2012 |
Antagonism of orexin-1 receptors attenuates swim- and restraint stress-induced antinociceptive behaviors in formalin test.
Topics: Analgesia; Animals; Benzoxazoles; Formaldehyde; Immobilization; Naloxone; Naphthyridines; Orexin Receptors; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Stress, Physiological; Swimming; Urea | 2012 |
Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Arginine; Behavior, Animal; Cymenes; Disease Models, Animal; Formaldehyde; Hot Temperature; Male; Mice; Mice, Inbred Strains; Monoterpenes; Motor Activity; Naloxone; Narcotic Antagonists; Oils, Volatile; Origanum; Pain; Phytotherapy; Plant Extracts; Thymus Plant | 2012 |
Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice.
Topics: Acetic Acid; Acute Pain; Analgesics; Animals; Arginine; Behavior, Animal; Capsaicin; Disease Models, Animal; Formaldehyde; Glutamic Acid; Glyburide; Lecythidaceae; Male; Mice; Naloxone; Narcotic Antagonists; Phytotherapy; Plant Extracts; Plant Leaves | 2013 |
Antinociceptive profiles and mechanisms of orally administered coumarin in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Behavior, Animal; Coumarins; Formaldehyde; Glutamic Acid; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Receptors, Opioid; Substance P | 2013 |
NESS002ie: a new fluorinated thiol endopeptidase inhibitor with antinociceptive activity in an animal model of persistent pain.
Topics: Analgesics; Animals; Disease Models, Animal; Formaldehyde; Male; Mice; Naloxone; Pain, Intractable; Protease Inhibitors; Sulfhydryl Compounds; Tyrosine | 2013 |
Naloxone blocks the beneficial effects of aqueous extract of Murraya koenigii (L.) Spreng leaves in models of pain.
Topics: Analgesics; Analgesics, Opioid; Animals; Formaldehyde; Hot Temperature; Male; Mice; Morphine; Murraya; Naloxone; Narcotic Antagonists; Pain Measurement; Plant Extracts; Plant Leaves; Reaction Time | 2013 |
Mechanisms underlying the antinociceptive effect of mangiferin in the formalin test.
Topics: Analgesics; Animals; Capsaicin; Formaldehyde; Glyburide; Male; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Nociception; Quinoxalines; Rats; Rats, Wistar; Serotonin; Xanthones | 2013 |
The oral administration of trans-caryophyllene attenuates acute and chronic pain in mice.
Topics: Acute Pain; Administration, Oral; Analgesics; Animals; Cannabis; Chronic Pain; Formaldehyde; Hot Temperature; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Naloxone; Ocimum; Oils, Volatile; Phytotherapy; Plant Extracts; Polycyclic Sesquiterpenes; Sesquiterpenes | 2014 |
Anti-inflammatory and antinociceptive effects of Sterculia striata A. St.-Hil. & Naudin (Malvaceae) in rodents.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Capsaicin; Carrageenan; Dextrans; Edema; Formaldehyde; Glutamic Acid; Histamine; Inflammation; Male; Mice; Naloxone; Pain; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Rats, Wistar; Sterculia | 2014 |
Chronic administration of modafinil induces hyperalgesia in mice: reversal by L-NG-nitro-arginine methyl ester and 7-nitroindazole.
Topics: Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Central Nervous System Stimulants; Formaldehyde; Hot Temperature; Hyperalgesia; Indazoles; Male; Mice; Modafinil; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain | 2014 |
Interaction between the dopaminergic and opioidergic systems in dorsal hippocampus in modulation of formalin-induced orofacial pain in rats.
Topics: Animals; Benzazepines; CA1 Region, Hippocampal; Dopamine; Dopamine Agonists; Dopamine Antagonists; Facial Pain; Formaldehyde; Male; Naloxone; Narcotic Antagonists; Opioid Peptides; Rats; Rats, Wistar | 2014 |
Evaluation of antinociceptive effect of ethanol extract of Hedyotis corymbosa Linn. whole plant in mice.
Topics: Acetic Acid; Analgesics; Animals; Ethanol; Female; Formaldehyde; Glutamic Acid; Hedyotis; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Receptors, Opioid; Solvents | 2015 |
The role of nicotinic acetylcholine and opioid systems of the ventral orbital cortex in modulation of formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Therapy, Combination; Facial Pain; Formaldehyde; Locomotion; Male; Mecamylamine; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Prefrontal Cortex; Pyridines; Rats | 2015 |
Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice.
Topics: Acetic Acid; Acrolein; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Bangladesh; Behavior, Animal; Formaldehyde; Glutamic Acid; Male; Medicine, Traditional; Mice; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Phytotherapy; Plant Extracts; Plant Leaves; Polygonum | 2015 |
Role of the thalamic submedius nucleus histamine H1 and H 2 and opioid receptors in modulation of formalin-induced orofacial pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Facial Pain; Formaldehyde; Histamine Agonists; Histamine Antagonists; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Opioid; Thalamic Nuclei | 2015 |
Pharmacological evidence favouring the traditional use of the root bark of Condalia buxifolia Reissek in the relief of pain and inflammation in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Behavior, Animal; Edema; Female; Formaldehyde; Glutamic Acid; Hot Temperature; Medicine, Traditional; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Plant Roots; Rhamnaceae | 2015 |
Anti-nociceptive activity of a few structurally related trimethoxy flavones and possible mechanisms involved.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Flavones; Formaldehyde; Male; Mice; Naloxone; Pain; Pain Measurement; Plant Extracts | 2016 |
Effects of intrathecal amylin on formalin-induced nociception and on cAMP accumulation in the rat embryonic spinal cells.
Topics: Amylin Receptor Agonists; Analgesics; Analgesics, Opioid; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Formaldehyde; Inflammation; Injections, Spinal; Islet Amyloid Polypeptide; Male; Morphine; Naloxone; Narcotic Antagonists; Nociception; Pain; Pain Threshold; Peptide Fragments; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, Islet Amyloid Polypeptide; Spinal Cord | 2016 |
Coactivation of μ- and κ-Opioid Receptors May Mediate the Protective Effect of Testosterone on the Development of Temporomandibular Joint Nociception in Male Rats.
Topics: Animals; Brain Stem; Facial Pain; Formaldehyde; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Nociceptive Pain; Orchiectomy; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Temporomandibular Joint; Temporomandibular Joint Disorders; Testosterone; Trigeminal Caudal Nucleus | 2016 |
Involvement of opioid receptors in the systemic and peripheral antinociceptive actions of montelukast in the animal models of pain.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclopropanes; Disease Models, Animal; Drug Synergism; Formaldehyde; Male; Mice; Naloxone; Pain; Quinolines; Rats; Receptors, Opioid; Sulfides; Visceral Pain | 2016 |
Evaluation of antinociceptive activity of methanolic extract of leaves of Stephania japonica Linn.
Topics: Acetic Acid; Analgesics; Animals; Formaldehyde; Glutamic Acid; Hot Temperature; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, Opioid; Stephania | 2016 |
Antinociceptive effects of dehydrocorydaline in mouse models of inflammatory pain involve the opioid receptor and inflammatory cytokines.
Topics: Acetates; Alkaloids; Analgesics; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Humans; Injections, Intraperitoneal; Mice; Naloxone; Pain; Receptors, Opioid | 2016 |
Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor.
Topics: Analgesics; Animals; Berberine Alkaloids; Chronic Pain; Ethylenediamines; Formaldehyde; Gene Expression Regulation; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naloxone; Neuralgia; Pain Management; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma; Sigma-1 Receptor; Spinal Cord | 2016 |
Effects of intra-hippocampal microinjection of vitamin B
Topics: Analgesics; Animals; CA1 Region, Hippocampal; Catheters, Indwelling; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Facial Pain; Formaldehyde; Male; Maze Learning; Memory Disorders; Microinjections; Motor Activity; Naloxone; Narcotic Antagonists; Nootropic Agents; Rats, Wistar; Scopolamine; Vibrissae; Vitamin B 12 | 2017 |
Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States.
Topics: Acetic Acid; Animals; Capsaicin; Corticosterone; Cues; Disease Models, Animal; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Nociception; Pain; Receptors, Opioid; Recognition, Psychology; Social Behavior; Stress, Psychological; Visual Perception | 2017 |
New
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Coffee; Disease Models, Animal; Female; Formaldehyde; Glutamic Acid; Hot Temperature; Hyperalgesia; Male; Mice; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Piperidines; Pyrazoles; Serotonin | 2018 |
Eslicarbazepine acetate reduces trigeminal nociception: Possible role of adrenergic, cholinergic and opioid receptors.
Topics: Adrenergic Antagonists; Analgesics; Animals; Atropine; Cholinergic Antagonists; Dibenzazepines; Formaldehyde; Male; Mice; Naloxone; Narcotic Antagonists; Pain; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Opioid; Trigeminal Neuralgia; Yohimbine | 2018 |
Possible involvement of the μ opioid receptor in the antinociception induced by sinomenine on formalin-induced nociceptive behavior in mice.
Topics: Administration, Oral; Analgesics; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morphinans; Naloxone; Naltrexone; Nociception; Receptors, Opioid, mu; Spinal Cord | 2019 |
Involvement of serotonergic and opioidergic systems in the antinociceptive effect of ketamine-magnesium sulphate combination in formalin test in rats.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Formaldehyde; Ketamine; Magnesium Sulfate; Male; Methysergide; Naloxone; Pain; Pain Measurement; Rats; Rats, Wistar; Serotonergic Neurons | 2019 |
The analgesic effect of refeeding on acute and chronic inflammatory pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chronic Pain; Disease Models, Animal; Eating; Food Deprivation; Formaldehyde; Freund's Adjuvant; Glucose; Hot Temperature; Hyperalgesia; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Pain Management; Pain Measurement; Rimonabant | 2019 |
Pharmacological evaluation underlying the antinociceptive activity of two new hybrids NSAIDs tetrahydropyran derivatives.
Topics: Adenosine Triphosphate; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Cyclooxygenase Inhibitors; Dizocilpine Maleate; Formaldehyde; Glyburide; Humans; Male; Mice; Naloxone; Naltrexone; NG-Nitroarginine Methyl Ester; Pain; Pain Measurement; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2020 |
Lemairamin, isolated from the Zanthoxylum plants, alleviates pain hypersensitivity via spinal α7 nicotinic acetylcholine receptors.
Topics: Aconitine; Acrylamides; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; beta-Endorphin; Cancer Pain; Female; Formaldehyde; Hyperalgesia; Injections, Spinal; Interleukin-10; Male; Mice; Microglia; Minocycline; Naloxone; Neuralgia; Rats; Rats, Wistar; Spinal Cord; Zanthoxylum | 2020 |
Isolation, Identification and Structural Verification of a Methylene-Bridged Naloxone "Dimer" Formed by Formaldehyde.
Topics: Chromatography, High Pressure Liquid; Formaldehyde; Magnetic Resonance Spectroscopy; Naloxone; Polymers; Solid Phase Extraction | 2022 |
Analagesic and Anti-Inflammatory Potentials of a Less Ulcerogenic Thiadiazinethione Derivative in Animal Models: Biochemical and Histochemical Correlates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Edema; Formaldehyde; Naloxone; Stomach Ulcer; Tramadol; Ulcer | 2022 |
Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats.
Topics: Analgesics; Animals; Atropine Derivatives; Clonidine; Formaldehyde; Humans; Hyperalgesia; Naloxone; Narcotic Antagonists; Neostigmine; Pain; Pentazocine; Rats; Rats, Sprague-Dawley | 2022 |
Histamine and its H 1 receptors in the ventral pallidum mediate formalin-induced pain-related behaviors through this region and spinal cord opioid receptors.
Topics: Animals; Basal Forebrain; Formaldehyde; Histamine; Histamine Agonists; Naloxone; Pain; Receptors, Opioid; Spinal Cord | 2023 |