Compounds > formaldehyde

formaldehyde and enkephalin, ala(2)-mephe(4)-gly(5)-

formaldehyde has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's6 (42.86)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basbaum, AI; Gogas, KR; Levine, JD; Presley, RW1
Calcagnetti, DJ; Fanselow, MS; Helmstetter, FJ1
Dickenson, AH; Sullivan, AF1
Abbott, FV; Hong, Y1
Chapman, V; Dickenson, AH; Haley, JE1
Cowan, A; Hunter, JC; Kovelowski, CJ; Lai, J; Malan, TP; Ossipov, MH; Porreca, F; Wheeler-Aceto, H1
Labuz, D; Machelska, H; Przewłocka, B; Przewłocki, R1
Basbaum, AI; Hammond, DL; Nakashima, N; Wang, H1
Gebhart, GF; Joshi, SK; Porreca, F; Su, X1
Sadan, G; Tasatargil, A1
Juma, F; Kanui, TI; Maloiy, GM; Olongida Ole Miaron, J; Towett, PK1
Fujita-Hamabe, W; Harada, S; Nagae, R; Nakamoto, K; Nawa, A; Tokuyama, S1
Beaudry, H; Dubois, D; Gendron, L1
Choi, EJ; Kim, KS; Park, JO; Roh, DH; Shin, HS; Woo, J; Yoon, SY1

Other Studies

14 other study(ies) available for formaldehyde and enkephalin, ala(2)-mephe(4)-gly(5)-

ArticleYear
The antinociceptive action of supraspinal opioids results from an increase in descending inhibitory control: correlation of nociceptive behavior and c-fos expression.
    Neuroscience, 1991, Volume: 42, Issue:3

    Topics: Amino Acid Sequence; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Foot; Formaldehyde; Gene Expression Regulation; Injections, Intraventricular; Male; Molecular Sequence Data; Naloxone; Neurons; Pain; Pain Measurement; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Single-Blind Method; Spinal Cord

1991
Analgesia produced by centrally administered DAGO, DPDPE and U50488H in the formalin test.
    European journal of pharmacology, 1988, Aug-09, Volume: 153, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Formaldehyde; Injections, Intraventricular; Male; Nociceptors; Pyrrolidines; Rats

1988
Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin.
    Pain, 1987, Volume: 30, Issue:3

    Topics: Animals; Drug Administration Schedule; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Formaldehyde; Injections, Spinal; Male; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Spinal Cord

1987
Peripheral opioid modulation of pain and inflammation in the formalin test.
    European journal of pharmacology, 1995, Apr-13, Volume: 277, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Extravasation of Diagnostic and Therapeutic Materials; Formaldehyde; Inflammation; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Narcotics; Pain; Pyrrolidines; Rats; Receptors, Opioid

1995
Electrophysiologic analysis of preemptive effects of spinal opioids on N-methyl-D-aspartate receptor-mediated events.
    Anesthesiology, 1994, Volume: 81, Issue:6

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Formaldehyde; Morphine; Narcotics; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1994
Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: demonstration of an opioid kappa and delta inhibitory tone.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2

    Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Formaldehyde; Immune Sera; Male; Naloxone; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa

1996
Inhibition of nitric oxide synthase enhances antinociception mediated by mu, delta and kappa opioid receptors in acute and prolonged pain in the rat spinal cord.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Formaldehyde; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid; Spinal Cord

1997
Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1

    Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Formaldehyde; Male; Oligopeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord

1998
kappa -opioid receptor agonists modulate visceral nociception at a novel, peripheral site of action.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Aug-01, Volume: 20, Issue:15

    Topics: Acetamides; Analgesics, Opioid; Animals; Colon; Disinfectants; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Ganglia, Spinal; Male; Nociceptors; Oligonucleotides, Antisense; Oligopeptides; Pain; Physical Stimulation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Rectum; Visceral Afferents

2000
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:1

    Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar

2004
Activation of micro, delta or kappa opioid receptors by DAMGO, DPDPE, U-50488 or U-69593 respectively causes antinociception in the formalin test in the naked mole-rat (Heterocephalus glaber).
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzeneacetamides; Data Interpretation, Statistical; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Formaldehyde; Injections, Intraperitoneal; Male; Mole Rats; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2009
Involvement of kappa opioid receptors in the formalin-induced inhibition of analgesic tolerance to morphine via suppression of conventional protein kinase C activation.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:8

    Topics: Analgesics, Opioid; Animals; Brain; Chronic Disease; Disease Models, Animal; Down-Regulation; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Formaldehyde; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Morphine; Naphthalenes; Oligonucleotides, Antisense; Pain; Pain Measurement; Pain Threshold; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Opioid, kappa; Receptors, Opioid, mu; Time Factors

2010
Activation of spinal mu- and delta-opioid receptors potently inhibits substance P release induced by peripheral noxious stimuli.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Sep-14, Volume: 31, Issue:37

    Topics: Animals; Capsaicin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice; Mice, Knockout; Neurons; Neurons, Afferent; Oligopeptides; Pain; Pain Measurement; Protein Precursors; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Opioid, delta; Receptors, Opioid, mu; Spinal Cord; Substance P; Tachykinins

2011
Intrathecal RGS4 inhibitor, CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Formaldehyde; Injections, Spinal; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Narcotic Antagonists; Nociception; Nociceptive Pain; Pain Measurement; Receptors, Opioid, mu; RGS Proteins; Spinal Cord; Thiazolidinediones; Time Factors

2015