Page last updated: 2024-09-03

forasartan and l 158809

forasartan has been researched along with l 158809 in 4 studies

Compound Research Comparison

Studies (forasartan)	Trials (forasartan)	Recent Studies (post-2010) (forasartan)	Studies (l 158809)	Trials (l 158809)	Recent Studies (post-2010) (l 158809)
15	1	0	137	0	7

Protein Interaction Comparison

Protein	Taxonomy	l 158809 (IC50)
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0021
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0012
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0015
Type-1 angiotensin II receptor	Oryctolagus cuniculus (rabbit)	0.0003
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0021
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0002
5-hydroxytryptamine receptor 1A	Mus musculus (house mouse)	0.0021

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (50.00)	18.2507
2000's	1 (25.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR	1
Anzini, M; Cappelli, A; De Benedetti, PG; Ferrari, F; Gallelli, A; Giorgi, G; Makovec, F; Mennuni, L; Menziani, MC; Pericot Mohr Gl, Gl; Rizzo, M; Vomero, S	1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR	1
Bauer, JH; Reams, GP	1

Reviews

3 review(s) available for forasartan and l 158809

Article	Year
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship	1996
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan	2010
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs. Archives of internal medicine, 1995, Jul-10, Volume: 155, Issue:13 Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	1995

Other Studies

1 other study(ies) available for forasartan and l 158809

Article	Year
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure. Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Imidazoles; In Vitro Techniques; Isometric Contraction; Ligands; Liver; Male; Models, Molecular; Molecular Structure; Muscle, Smooth, Vascular; Purines; Pyridines; Quinolines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles	2004

Article

Year

Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.

Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Imidazoles; In Vitro Techniques; Isometric Contraction; Ligands; Liver; Male; Models, Molecular; Molecular Structure; Muscle, Smooth, Vascular; Purines; Pyridines; Quinolines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles

2004