Page last updated: 2024-09-03

forasartan and angiotensin ii

forasartan has been researched along with angiotensin ii in 10 studies

Compound Research Comparison

Studies (forasartan)	Trials (forasartan)	Recent Studies (post-2010) (forasartan)	Studies (angiotensin ii)	Trials (angiotensin ii)	Recent Studies (post-2010) (angiotensin ii)
15	1	0	38,152	1,089	7,413

Protein Interaction Comparison

Protein	Taxonomy	angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.002
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.002
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0018
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0055
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.004
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0011

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (60.00)	18.2507
2000's	4 (40.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anzini, M; Cappelli, A; De Benedetti, PG; Ferrari, F; Gallelli, A; Giorgi, G; Makovec, F; Mennuni, L; Menziani, MC; Pericot Mohr Gl, Gl; Rizzo, M; Vomero, S	1
Bittner, SE; Brown, MA; Chen, ST; Corpus, VM; McGraw, DE; McMahon, EG; Null, CL; Olins, GM; Palomo, MA; Smits, GJ	1
Hamaguchi, A; Iwao, H; Kim, S; Miura, K; Ohta, K; Takaori, K; Yukimura, T	1
Furukawa, T; Usune, S	1
Brunner, HR; Burns, TS; Hagmann, M; Karim, A; Naudin, RB; Nussberger, J; Waeber, B	1
Babler, MA; Cook, CS; McMahon, EG; Olins, GM; Palomo, MA; Suleymanov, OD; Yang, PC	1
Abe, Y; Aki, Y; Kimura, S; Kiyomoto, K; Nishiyama, A; Tomohiro, A	1
Furukawa, T; Katsuragi, T; Kushiku, K; Shibata, K; Tokunaga, R; Yamada, H	1
Guangyuan, L; Honda, K; Katsuragi, T; Sato, C	1
Krovat, EM; Langer, T	1

Trials

1 trial(s) available for forasartan and angiotensin ii

Article	Year
SC-52458, an orally active angiotensin II-receptor antagonist: inhibition of blood pressure response to angiotensin II challenges and pharmacokinetics in normal volunteers. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4 Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Humans; Injections, Intravenous; Male; Pyridines; Radioimmunoassay; Renin; Single-Blind Method; Tetrazoles; Vasoconstrictor Agents	1997

Article

Year

SC-52458, an orally active angiotensin II-receptor antagonist: inhibition of blood pressure response to angiotensin II challenges and pharmacokinetics in normal volunteers.

Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:4

Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Humans; Injections, Intravenous; Male; Pyridines; Radioimmunoassay; Renin; Single-Blind Method; Tetrazoles; Vasoconstrictor Agents

1997

Other Studies

9 other study(ies) available for forasartan and angiotensin ii

Article	Year
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure. Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Imidazoles; In Vitro Techniques; Isometric Contraction; Ligands; Liver; Male; Models, Molecular; Molecular Structure; Muscle, Smooth, Vascular; Purines; Pyridines; Quinolines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles	2004
Pharmacology of SC-52458, an orally active, nonpeptide angiotensin AT1 receptor antagonist. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4 Topics: Administration, Oral; Adrenal Cortex; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Blood Pressure; Female; Heart Rate; Hypertension; In Vitro Techniques; Male; Muscle, Smooth; Peptidyl-Dipeptidase A; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin; Tetrazoles; Uterus	1993
Role of angiotensin II in extracellular matrix and transforming growth factor-beta 1 expression in hypertensive rats. European journal of pharmacology, 1994, Sep-15, Volume: 269, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Blotting, Northern; Captopril; Collagen; Extracellular Matrix; Gene Expression Regulation; Heart Ventricles; Hypertension; Male; Organ Size; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta	1994
Effects of SC-52458, a new nonpeptide angiotensin II receptor antagonist, on increase in cytoplasmic Ca2+ concentrations and contraction induced by angiotensin II and K(+)-depolarization in guinea-pig taenia coli. General pharmacology, 1996, Volume: 27, Issue:7 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atropine; Calcium; Colon; Cytoplasm; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Parasympatholytics; Potassium; Pyridines; Tetrazoles; Tetrodotoxin	1996
Effects of SC-52458, an angiotensin AT1 receptor antagonist, in the dog. American journal of hypertension, 1997, Volume: 10, Issue:6 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Hypertension, Renovascular; Pyridines; Rabbits; Rats; Tetrazoles	1997
The role of basally synthesized nitric oxide in modulating the renal vasoconstrictor action of angiotensin II. Hypertension research : official journal of the Japanese Society of Hypertension, 1997, Volume: 20, Issue:4 Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine; Dogs; Enzyme Inhibitors; Female; Kidney; Male; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phenylephrine; Pyridines; Renal Artery; Renal Circulation; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	1997
Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia. Circulation research, 2001, Jan-19, Volume: 88, Issue:1 Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Atropine; Blotting, Northern; Captopril; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Sympathetic; Gene Expression Regulation; Heart; Heart Rate; Pentolinium Tartrate; Pyridines; RNA, Messenger; Stellate Ganglion; Tetrazoles; Tissue Distribution; Up-Regulation	2001
Inositol(1,4,5)trisphosphate signal triggers a receptor-mediated ATP release. Biochemical and biophysical research communications, 2002, May-03, Volume: 293, Issue:2 Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcium Channels; Calcium Signaling; Cell Line; Cells, Cultured; Colon; Guinea Pigs; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Muscle, Smooth; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Tetrazoles	2002
Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification. Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5 Topics: Acrylates; Algorithms; Angiotensin II; Biphenyl Compounds; Databases, Factual; Imidazoles; Lactones; Losartan; Models, Molecular; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfones; Tetrazoles; Thiophenes	2003