fomesafen has been researched along with baclofen in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 34 (36.17) | 18.7374 |
1990's | 25 (26.60) | 18.2507 |
2000's | 25 (26.60) | 29.6817 |
2010's | 8 (8.51) | 24.3611 |
2020's | 2 (2.13) | 2.80 |
Authors | Studies |
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Konishi, S; Otsuka, M | 1 |
Davidoff, RA | 1 |
Fukuda, H; Kudo, Y; Ono, H | 2 |
Baltzer, V; Bencze, WL; Demiéville, H; Haas, HL; Koella, WP; Olpe, HR; Wolf, P | 1 |
Burke, DJ | 1 |
Merrill, DC; Teague, CT | 1 |
Del Bianco, E; Giuliani, S; Lecci, A; Maggi, CA; Santicioli, P | 1 |
Kunos, G; Varga, K | 1 |
Sved, AF; Tsukamoto, K | 1 |
D'Luzansky, SC; Herman, RM; Ippolito, R | 1 |
Milanov, IG | 1 |
Gomi, Y; Hashimoto, S; Ito, Y; Kato, H; Morikawa, K; Yamauchi, T | 1 |
Bickerton, R; Dehoux, E; Hugenholtz, H; Nelson, RF | 1 |
al-Zamil, Z; Bagust, J; Kerkut, GA | 1 |
Kotak, VC; Page, CH | 1 |
Akagi, H; Yanagisawa, M | 1 |
LaBella, FS; Lewis, JL; Westerberg, VS | 1 |
Berzsenyi, P; Farkas, S; Tarnawa, I | 1 |
Conte, B; Furio, M; Giuliani, S; Gragnani, L; Maggi, CA; Meli, A; Meli, P; Santicioli, P | 1 |
Bousquet, P; Feldman, J; Schwartz, J | 1 |
Singh, R; Ticku, MK | 1 |
Chweh, AY; Swinyard, EA; Wolf, HH | 1 |
Aihara, M; Goto, M; Tamai, K; Tanabe, Y | 1 |
Young, RR | 1 |
Penn, RD | 1 |
Fukuda, H; Kaneko, T; Ono, H | 1 |
Furukawa, K; Hori, M; Ito, T; Kadokawa, T; Karasawa, T | 1 |
Alexandre, F; Angelini, L; Benezech, J; Broggi, G; Claverie, P; Deonna, T; Frerebeau, P; Lazorthes, Y; Siegfried, J; Verdie, JC | 1 |
Tan, U | 1 |
Smith, DF | 1 |
Persson, B | 1 |
Labella, FS; Sawynok, J | 1 |
Harrison, FG | 1 |
Bornstein, JC; Curtis, DR; Lodge, D; Peet, MJ | 1 |
Davies, J | 1 |
Bloch, R; Bousquet, P; Feldman, J; Schwartz, J | 1 |
Arzbaecher, RC; Beissinger, RL; Kroin, JS; Penn, RD | 1 |
Pedersen, E | 1 |
Furukawa, K; Ito, T; Kadokawa, T; Karasawa, T; Shimizu, M | 1 |
Ono, H | 1 |
Clark, WG; Menon, MK; Vivonia, C | 1 |
Lalley, PM | 1 |
Trippenbach, T | 1 |
Andre, P; Horn, E; Pompeiano, O | 1 |
Andre, P; d'Ascanio, P; Manzoni, D; Pompeiano, O | 1 |
Cristoni, A; Nizzola, R; Pifferi, G | 1 |
Sakitama, K | 1 |
Hammond, DL; Washington, JD | 1 |
Brugger, F; Froestl, W; Mickel, S; Olpe, HR; Wicki, U | 1 |
Ault, B; Hildebrand, LM | 1 |
Benneton, C; Garcia-Larrea, L; Mertens, P; Millet, MF; Parise, M; Sindou, M | 1 |
García-Larrea, L; Mauguière, F; Mertens, P; Parise, M; Sindou, M | 1 |
Seifert, E; Trippenbach, T | 1 |
Curtis, DR; Lacey, G | 1 |
Endo, M; Suzuki, M; Tetsuka, M | 1 |
Grillner, S; Parker, D; Svensson, E; Ullström, M | 1 |
Bonagamba, LG; Callera, JC; Laguzzi, R; Machado, BH; Nosjean, A | 1 |
Advokat, C; Duke, M; Zeringue, R | 1 |
Adachi, K; Deguchi, K; Kimura, S; Saito, Y | 1 |
Dicpinigaitis, PV; Grimm, DR; Lesser, M | 1 |
Advokat, C; Duke, M | 1 |
Balerio, GN; Diaz, SL; Kemmling, AK; Rubio, MC | 1 |
Agabio, R; Brunetti, G; Carai, MA; Colombo, G; Diaz, G; Gessa, GL; Littera, M; Lobina, C; Melis, S; Pani, M; Reali, R; Serra, S; Vacca, G | 1 |
Burns, AS; Meythaler, JM | 1 |
Lang, IM; Medda, BK; Shaker, R | 1 |
Brunetti, G; Carai, MA; Cignarella, G; Colombo, G; Gessa, GL; Mastinu, S; Melis, S; Minardi, G; Pistuddi, AM; Serra, S; Solinas, C; Vacca, G | 1 |
Dachy, B; Dan, B | 1 |
Boz, C; Bulbul, I; Ozmenoglu, M; Velioglu, S | 1 |
Iida, R; Kobayashi, T; Nakamura, T; Ogawa, S; Saeki, S; Tamura, M | 1 |
Dyba, S; Klukowska, L; Nadulska, A; Tychowska, I | 1 |
Carai, MA; Colombo, G; Froestl, W; Gessa, GL; Serra, S; Vacca, G | 1 |
Besheer, J; Hodge, CW; Lepoutre, V | 1 |
Conklin, JL; Wise, J | 1 |
Bennett, DJ; Harvey, PJ; Li, X; Li, Y | 1 |
Hardy, EL; Hoving, MA; Spincemaille, GH; van Kranen-Mastenbroek, VH; van Raak, EP; Vles, JS | 1 |
Chan, SW; Li, P; Lin, G; Rudd, JA | 1 |
Burnett, A; Cook, IJ; Fuentealba, SE; Szczesniak, MM | 1 |
Katsura, Y; Mino, T; Seki, T; Sugimoto, S; Tsubouchi, T; Tsujimoto, S | 1 |
Bongianni, F; Cinelli, E; Fontana, GA; Mutolo, D; Pantaleo, T | 1 |
Huwyler, J; Knoflach, F; Kolb, Y; Kratzeisen, C; Malherbe, P; Marcuz, A; Masciadri, R; Nakagawa, T; Norcross, RD; Porter, RH; Prinssen, EP; Sleight, AJ; Spooren, W; Thomas, AW; Wettstein, JG; Zenner, MT | 1 |
Gao, J; Gao, XY; Liao, ZH; Shi, Z; Wang, W; Zhong, MK; Zhou, LM; Zhu, GQ | 1 |
Kofler, M; Kumru, H; Portell, E; Valls-Solé, J; Vidal, J | 1 |
Bresolin, N; Pecori, A; Zucca, C | 1 |
Dietz, V; Petersen, JA; Schubert, M | 1 |
Baizer, JS; Broussard, DM; Heskin-Sweezie, R; Titley, HK | 1 |
Bongianni, F; Cinelli, E; Mutolo, D; Pantaleo, T | 1 |
Brusberg, M; Kakol-Palm, D; Larsson, H; Lindström, E; Martinez, V; Novén, A; Påhlman, I; Ravnefjord, A | 1 |
Kofler, M; Stetkarova, I | 1 |
Gündüz, A; Karamehmetoğlu, ŞS; Kızıltan, ME; Örnek, Nİ; Ünalan, H; Uzun, N | 1 |
Chalimoniuk, M; Gálik, J; Hricová, Ľ; Kisucká, A; Langfort, J; Lukáčová, N; Maršala, M; Pavel, J; Radoňak, J; Strosznajder, JB | 1 |
Heckman, CJ; Imhoff-Manuel, R; Klein, DA; Manuel, M; Tresch, MC; Tysseling, VM | 1 |
Babalova, L; Dobrolubov, B; Jakus, J; Kotmanova, Z; Martvon, L; Pitts, T; Poliacek, I; Simera, M; Veternik, M | 1 |
Badri, H; Canning, BJ; Denton, D; Dockry, RJ; Escott, J; Holt, A; Holt, K; LGibbard, C; Satia, I; Smith, JA; Wilkinson, G | 1 |
4 review(s) available for fomesafen and baclofen
Article | Year |
---|---|
Pharmacology of spasticity.
Topics: Baclofen; Benzodiazepines; Dantrolene; Humans; Muscle Spasticity; Neurotransmitter Agents; Phenothiazines; Reflex; Spinal Cord | 1978 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bicuculline; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Central Nervous System; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rabbits; Reflex; Reticular Formation; Synaptic Transmission; Vasomotor System; Vasopressins | 1985 |
[Functional neurosurgery of cerebral palsy].
Topics: Adolescent; Adult; Animals; Baclofen; Benzodiazepines; Brain; Brain Diseases; Cerebellar Cortex; Cerebellar Nuclei; Cerebellum; Cerebral Palsy; Child; Child, Preschool; Drug Implants; Electric Stimulation Therapy; Female; Follow-Up Studies; Glycine; Humans; Infant, Newborn; Infant, Premature; Injections, Spinal; Morphine; Muscle Spasticity; Nervous System; Neurosurgical Procedures; Physical Therapy Modalities; Pregnancy; Reflex; Spinal Cord; Spinal Nerve Roots; Thalamus | 1985 |
Gastroesophageal reflux disease and baclofen: is there a light at the end of the tunnel?
Topics: Animals; Baclofen; Esophagogastric Junction; GABA Agonists; Gastroesophageal Reflux; Humans; Manometry; Reflex; Vagus Nerve | 2004 |
10 trial(s) available for fomesafen and baclofen
Article | Year |
---|---|
Intrathecal baclofen suppresses central pain in patients with spinal lesions. A pilot study.
Topics: Adult; Baclofen; Double-Blind Method; Female; Humans; Injections, Spinal; Male; Middle Aged; Pain; Reflex; Sensation; Spasm; Spinal Cord Diseases; Spinal Cord Injuries | 1992 |
Intrathecal baclofen for intractable spinal spasticity--a double-blind cross-over comparison with placebo in 6 patients.
Topics: Adult; Baclofen; Catheterization; Disability Evaluation; Double-Blind Method; Female; Humans; Injections, Spinal; Male; Reflex; Spinal Diseases | 1992 |
Intrathecal baclofen in tetraplegia of spinal origin: efficacy for upper extremity hypertonia.
Topics: Adult; Arm; Baclofen; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Leg; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Quadriplegia; Reflex; Spinal Cord Injuries; Treatment Outcome | 2001 |
Electrophysiological assessment of the effect of intrathecal baclofen in spastic children.
Topics: Adolescent; Baclofen; Child; Child, Preschool; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Female; GABA Agonists; H-Reflex; Humans; Infant; Injections, Spinal; Magnetics; Male; Muscle Relaxants, Central; Muscle Spasticity; Reflex; Sensory Thresholds; Transcutaneous Electric Nerve Stimulation; Treatment Outcome | 2002 |
Baclofen is effective in intractable hiccups induced by brainstem lesions.
Topics: Adult; Aged; Baclofen; Brain Stem; Brain Stem Infarctions; Chronic Disease; GABA Agonists; gamma-Aminobutyric Acid; Hiccup; Humans; Middle Aged; Neural Inhibition; Prospective Studies; Reflex; Synaptic Transmission; Treatment Outcome | 2001 |
Placebo controlled utility and feasibility study of the H-reflex and flexor reflex in spastic children treated with intrathecal baclofen.
Topics: Adolescent; Baclofen; Child; Dose-Response Relationship, Drug; Double-Blind Method; Electromyography; Feasibility Studies; Female; Functional Laterality; Humans; Injections, Spinal; Male; Muscle Relaxants, Central; Muscle Spasticity; Muscle, Skeletal; Reflex; Statistics, Nonparametric; Treatment Outcome | 2006 |
Differential relaxation and contractile responses of the human upper esophageal sphincter mediated by interplay of mucosal and deep mechanoreceptor activation.
Topics: Administration, Oral; Administration, Topical; Adult; Anesthetics, Local; Baclofen; Catheterization; Chemoreceptor Cells; Esophageal Sphincter, Upper; Female; GABA Agonists; Humans; Hydrochloric Acid; Infusions, Parenteral; Insufflation; Lidocaine; Male; Mechanoreceptors; Mechanotransduction, Cellular; Middle Aged; Mucous Membrane; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Peristalsis; Pressure; Reflex | 2008 |
Efficacy and tolerability of eperisone and baclofen in spastic palsy: a double-blind randomized trial.
Topics: Administration, Oral; Adult; Analysis of Variance; Baclofen; Chi-Square Distribution; Double-Blind Method; Electromyography; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Propiophenones; Range of Motion, Articular; Reflex; Reflex, Abnormal; Severity of Illness Index; Treatment Outcome; Walking | 2009 |
Differential effect of baclofen on cortical and spinal inhibitory circuits.
Topics: Adult; Baclofen; Cerebral Cortex; Female; GABA-B Receptor Agonists; H-Reflex; Humans; Injections, Spinal; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Muscle, Skeletal; Reaction Time; Reflex; Spinal Injuries; Spinal Nerves; Time Factors | 2013 |
Effect of centrally and peripherally acting GABA
Topics: Adult; Animals; Baclofen; Capsaicin; Cough; Double-Blind Method; Female; Humans; Reflex | 2021 |
80 other study(ies) available for fomesafen and baclofen
Article | Year |
---|---|
Substance P and excitatory transmitter of primary sensory neurons.
Topics: Amino Acids; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Glutamates; In Vitro Techniques; Membrane Potentials; Motor Neurons; Neurons; Neurons, Afferent; Neurotransmitter Agents; Picrotoxin; Rats; Reflex; Spinal Cord; Spinal Nerve Roots; Stimulation, Chemical; Substance P; Synapses; Synaptic Transmission | 1976 |
Effects of beta-(p-chlorophenyl)-GABA (baclofen) on spinal synaptic activity.
Topics: Action Potentials; Aminobutyrates; Animals; Anura; Baclofen; Drug Interactions; Fenclonine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rana catesbeiana; Rats; Reflex; Reserpine; Spinal Nerve Roots; Synapses; Tetrabenazine; Time Factors | 1977 |
The biological activity of d- and l-baclofen (Lioresal).
Topics: Aminobutyrates; Animals; Baclofen; Blood Pressure; Cats; Dose-Response Relationship, Drug; Male; Mice; Reflex; Seizures; Substantia Nigra; Synaptic Transmission | 1978 |
An approach to the treatment of spasticity.
Topics: Adrenergic alpha-Antagonists; Baclofen; Brain Diseases; Dantrolene; Diazepam; Humans; Mephenesin; Muscle Tonus; Muscular Diseases; Phenothiazines; Reflex; Sclerosing Solutions; Spasm; Spinal Diseases | 1975 |
Effect of baclofen and dantrolene on bladder stimulator-induced detrusor-sphincter dyssynergia in dogs.
Topics: Aminobutyrates; Animals; Baclofen; Dantrolene; Depression, Chemical; Dogs; Electric Stimulation; Female; Hydantoins; Male; Muscle Tonus; Pressure; Reflex; Spinal Cord Diseases; Urethra; Urinary Bladder | 1978 |
Effect of the GABAB antagonist, phaclofen, on baclofen-induced inhibition of micturition reflex in urethane-anesthetized rats.
Topics: Animals; Baclofen; Capsaicin; Cerebral Ventricles; Fenclonine; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Reflex; Urethane; Urinary Bladder; Urination | 1992 |
Inhibition of baroreflex bradycardia by ethanol involves both GABAA and GABAB receptors in the brainstem of the rat.
Topics: 3-Mercaptopropionic Acid; Animals; Baclofen; Bradycardia; Brain Stem; Electric Stimulation; Ethanol; Male; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex; Vagus Nerve | 1992 |
Tonic stimulation of GABAB receptors in the nucleus tractus solitarius modulates the baroreceptor reflex.
Topics: Animals; Aorta; Baclofen; Blood Pressure; Electric Stimulation; GABA-A Receptor Antagonists; Heart Rate; Male; Medulla Oblongata; Muscimol; Nervous System Physiological Phenomena; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reflex | 1992 |
Flexor reflex for assessment of common interneurone activity in spasticity.
Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Disorders; Clonidine; Electroacupuncture; Electromyography; Female; Hemiplegia; Humans; Interneurons; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Reaction Time; Reflex | 1992 |
Inhibitory effect of inaperisone hydrochloride (inaperisone), a new centrally acting muscle relaxant, on the micturition reflex.
Topics: Anesthesia; Animals; Atropine; Baclofen; Brain; Male; Mandelic Acids; Muscle Contraction; Muscle Relaxants, Central; Parasympatholytics; Propiophenones; Rats; Rats, Inbred Strains; Reflex; Synaptosomes; Tritium; Urinary Bladder | 1992 |
The effect of bicuculline and baclofen on the dorsal root-ventral root reflex in the isolated spinal cord.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Cricetinae; Electrodes; In Vitro Techniques; Mesocricetus; Receptors, GABA-A; Reflex; Reflex, Monosynaptic; Spinal Cord; Tubocurarine | 1991 |
GABA mediated inhibition of abdominal postural flexion in lobster.
Topics: Abdomen; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Interneurons; Muscimol; Nephropidae; Physical Stimulation; Picrotoxin; Posture; Reflex | 1991 |
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Mechanisms of general anesthesia: brain regional responses to baclofen.
Topics: Anesthesia, General; Animals; Arousal; Baclofen; Brain; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Nociceptors; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reflex; Seizures; Stereotyped Behavior | 1989 |
Effects of some centrally acting muscle relaxants on spinal root potentials: a comparative study.
Topics: Animals; Baclofen; Cats; Diazepam; Dose-Response Relationship, Drug; Male; Membrane Potentials; Mephenesin; Midazolam; Muscle Relaxants, Central; Reference Values; Reflex; Spinal Nerve Roots; Tolperisone | 1989 |
The effects of baclofen on spinal and supraspinal micturition reflexes in rats.
Topics: Animals; Baclofen; GABA Antagonists; Male; Rats; Receptors, GABA-A; Reflex; Urethra; Urinary Bladder; Urination | 1987 |
Central cardiovascular effects of baclofen in spontaneously hypertensive rats.
Topics: Animals; Baclofen; Blood Pressure; Brain; Heart Rate; Hypertension; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A; Reflex | 1987 |
Hypnotic action of pentobarbital in mice: a possible mechanism.
Topics: Animals; Baclofen; Bicuculline; Isoxazoles; Male; Mice; Oxazoles; Pentobarbital; Receptors, GABA-A; Reflex; Sleep | 1987 |
[An infant with kinesigenic reflex epilepsy which responded to baclofen].
Topics: Baclofen; Electroencephalography; Epilepsy; Female; Humans; Infant; Movement; Reflex; Wrist | 1988 |
The physiology of spasticity and its response to therapy.
Topics: Animals; Baclofen; Central Nervous System Diseases; Dantrolene; Diazepam; Humans; Motor Neurons; Muscle Spasticity; Reflex; Reflex, Stretch; Skin | 1988 |
Intrathecal baclofen for severe spasticity.
Topics: Activities of Daily Living; Baclofen; Electroencephalography; Electromyography; Equipment Failure; Extremities; Humans; Infusion Pumps; Injections, Spinal; Muscle Spasticity; Reflex; Sleep; Time Factors | 1988 |
Simultaneous evaluation of drug effects on both the spinal cord and the descending pathways in rats.
Topics: Animals; Baclofen; Conditioning, Operant; Efferent Pathways; Electric Stimulation; Male; Neural Pathways; Rats; Rats, Inbred Strains; Reflex; Reflex, Monosynaptic; Spinal Cord; Time Factors | 1987 |
Pharmacological studies of 1-(2,3-dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1- propanone hydrochloride (AD-2239), a centrally acting muscle relaxant.
Topics: Animals; Arousal; Baclofen; Behavior, Animal; Cats; Decerebrate State; Diazepam; Electroencephalography; Electromyography; Female; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Muscle Relaxants, Central; Muscle Rigidity; Propiophenones; Pyrrolidines; Rats; Rats, Inbred Strains; Reflex; Reflex, Stretch; Species Specificity; Tolperisone | 1985 |
Entropy concept in relation to brain waves and evoked potentials: critique of a physical approach.
Topics: Animals; Baclofen; Brain; Dogs; Electroencephalography; Evoked Potentials, Somatosensory; Humans; Models, Neurological; Motor Neurons; Muscles; Reflex; Thermodynamics | 1985 |
Stereoselectivity of spinal neurotransmission: effects of baclofen enantiomer on tail-flick reflex in rats.
Topics: Animals; Baclofen; Decerebrate State; Injections, Spinal; Male; Molecular Conformation; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Stereoisomerism; Synaptic Transmission; Tail | 1984 |
A hypertensive response to baclofen in the nucleus tractus solitarii in rats.
Topics: Anesthesia; Animals; Baclofen; Blood Pressure; Glutamates; Heart Rate; Hypertension; Male; Medulla Oblongata; Pressoreceptors; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Reflex | 1981 |
Naloxone antagonizes inhibitory and unmasks excitatory effects of baclofen.
Topics: Anesthesia; Animals; Baclofen; Male; Mice; Mice, Inbred Strains; Motor Activity; Naloxone; Reflex; Stereoisomerism | 1981 |
The effects of baclofen on gamma motoneurones supplying gastrocnemius muscle in the rabbit.
Topics: Animals; Ankle; Baclofen; Motor Neurons; Motor Neurons, Gamma; Muscle Spasticity; Muscle Spindles; Muscles; Rabbits; Reflex | 1982 |
Selective effects of (-)-baclofen on spinal synaptic transmission in the cat.
Topics: Action Potentials; Afferent Pathways; Animals; Baclofen; Cats; Interneurons; Reflex; Spinal Cord; Synapses; Synaptic Transmission | 1981 |
Selective depression of synaptic transmission of spinal neurones in the cat by a new centrally acting muscle relaxant, 5-chloro-4-(2-imidazolin-2-yl-amino)-2, 1, 3-benzothiodazole (DS103-282).
Topics: Amino Acids; Animals; Baclofen; Cats; Clonidine; Female; Male; Muscle Relaxants, Central; Neurons; Reflex; Spinal Cord; Synapses; Synaptic Transmission | 1982 |
Evidence for a neuromodulatory role of GABA at the first synapse of the baroreceptor reflex pathway. Effects of GABA derivatives injected into the NTS.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Pressoreceptors; Receptors, Cell Surface; Receptors, GABA-A; Reflex | 1982 |
Reduced spinal reflexes following intrathecal baclofen in the rabbit.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Hindlimb; Injections, Spinal; Male; Muscle Contraction; Rabbits; Reaction Time; Reflex; Spinal Cord; Synapses; Synaptic Transmission | 1984 |
Management of spasticity on neurophysiological basis.
Topics: Baclofen; Chlorpromazine; Cryosurgery; Curare; Dantrolene; Diazepam; Humans; Moxisylyte; Muscle Spasticity; Neuromuscular Nondepolarizing Agents; Propranolol; Reflex | 1980 |
Mechanisms of depressant action of muscle relaxants on spinal reflexes: participation of membrane stabilizing action.
Topics: Action Potentials; Animals; Baclofen; In Vitro Techniques; Lidocaine; Male; Membrane Potentials; Mephenesin; Motor Neurons; Muscle Relaxants, Central; Neuromuscular Junction; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Tolperisone | 1984 |
Effects of chlorpromazine, imipramine and baclofen on the spinal polysynaptic reflex in acute, chronic and 6-hydroxydopamine-treated spinal rats.
Topics: Animals; Baclofen; Blood Pressure; Chlorpromazine; Electromyography; Hydroxydopamines; Imipramine; Male; Oxidopamine; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Synapses | 1982 |
Animal techniques for evaluating muscle relaxants.
Topics: Action Potentials; Afferent Pathways; Anesthetics, Local; Animals; Baclofen; Decerebrate State; Lidocaine; Mephenesin; Muscle Relaxants, Central; Muscles; Rats; Reflex; Spinal Cord | 1982 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Motor Activity; Muscimol; Pain; Phencyclidine; Reflex | 1980 |
Inhibition of depressor cardiovascular reflexes by a derivative of gamma-aminobutyric acid (GABA) and by general anesthetics with suspected GABA-mimetic effects.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Chloralose; Female; gamma-Aminobutyric Acid; Male; Methohexital; Picrotoxin; Reflex; Sympathetic Nervous System; Urethane | 1980 |
Baclofen-induced block of the Hering-Breuer expiratory-promoting reflex in rats.
Topics: Animals; Baclofen; GABA Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Reflex; Respiration; Sodium Chloride; Time Factors; Trachea; Vagus Nerve | 1995 |
Microinjections of GABAergic agents in the locus coeruleus modify the gain of vestibulospinal reflexes in decerebrate cats.
Topics: Animals; Baclofen; Cats; GABA Agonists; Locus Coeruleus; Microinjections; Muscimol; Posture; Reflex; Vestibular Nerve | 1995 |
Depression of the vestibulospinal reflex adaptation by intravermal microinjection of GABA-A and GABA-B agonists in the cat.
Topics: Adaptation, Physiological; Animals; Baclofen; Cats; Cerebellum; Decerebrate State; Depression, Chemical; Electromyography; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Microinjections; Muscimol; Neck Muscles; Neurons; Reflex; Spinal Cord; Vestibule, Labyrinth | 1994 |
Synthesis and muscle relaxant activity of cyclic baclofen analogues.
Topics: Administration, Oral; Animals; Baclofen; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Muscle Relaxants, Central; Rabbits; Reflex; Synapses | 1994 |
The effects of centrally acting muscle relaxants on the intrathecal noradrenaline-induced facilitation of the flexor reflex mediated by group II afferent fibers in rats.
Topics: Animals; Baclofen; Chlorpromazine; Electromyography; Injections, Spinal; Male; Mephenesin; Muscle Relaxants, Central; Muscles; Nerve Fibers; Neurons, Afferent; Norepinephrine; Rats; Rats, Wistar; Reflex; Spinal Cord; Tolperisone | 1993 |
Antagonism of L-baclofen-induced antinociception by CGP 35348 in the spinal cord of the rat.
Topics: Analgesics; Animals; Baclofen; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Hot Temperature; Injections, Spinal; Isonicotinic Acids; Male; Nociceptors; Organophosphorus Compounds; Pain Measurement; Pain Threshold; Postural Balance; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord | 1993 |
The action of new potent GABAB receptor antagonists in the hemisected spinal cord preparation of the rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; In Vitro Techniques; Organophosphorus Compounds; Rats; Receptors, GABA-A; Reflex; Spinal Cord | 1993 |
Effects of excitatory amino acid receptor antagonists on a capsaicin-evoked nociceptive reflex: a comparison with morphine, clonidine and baclofen.
Topics: Animals; Baclofen; Capsaicin; Clonidine; Evoked Potentials; In Vitro Techniques; Morphine; Nociceptors; Rats; Receptors, Amino Acid; Reflex; Spinal Cord | 1993 |
Long-term clinical, electrophysiological and urodynamic effects of chronic intrathecal baclofen infusion for treatment of spinal spasticity.
Topics: Adolescent; Adult; Aged; Baclofen; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Injections, Spinal; Long-Term Care; Male; Middle Aged; Muscle Spasticity; Reflex; Spinal Diseases; Treatment Outcome; Urinary Bladder, Neurogenic; Urodynamics | 1995 |
Clinical use of polysynaptic flexion reflexes in the management of spasticity with intrathecal baclofen.
Topics: Adult; Baclofen; Dose-Response Relationship, Drug; Female; Humans; Infusion Pumps; Injections, Spinal; Leg; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Muscle, Skeletal; Pain; Pain Threshold; Reaction Time; Reflex; Synapses; Treatment Outcome | 1997 |
Effects of baclofen on the Hering-Breuer inspiratory-inhibitory and deflation reflexes in rats.
Topics: Animals; Baclofen; Diaphragm; Electromyography; GABA Agonists; GABA Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Reflex; Respiration; Solitary Nucleus | 1998 |
Prolonged GABA(B) receptor-mediated synaptic inhibition in the cat spinal cord: an in vivo study.
Topics: Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrophysiology; Female; GABA Agonists; GABA Antagonists; GABA Modulators; Male; Membrane Potentials; Motor Neurons; Neural Inhibition; Pentobarbital; Phosphinic Acids; Propanolamines; Receptors, GABA-A; Receptors, GABA-B; Reflex; Spinal Cord; Synapses | 1998 |
GABA(B) receptors in the nucleus tractus solitarii modulate the carotid chemoreceptor reflex in rats.
Topics: Animals; Baclofen; Carotid Arteries; Chemoreceptor Cells; GABA Agonists; Male; Rats; Rats, Wistar; Receptors, GABA-B; Reflex; Solitary Nucleus | 1999 |
Neuropeptide-mediated facilitation and inhibition of sensory inputs and spinal cord reflexes in the lamprey.
Topics: Action Potentials; Analgesics; Animals; Baclofen; Behavior, Animal; Bombesin; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; Lampreys; Male; N-Methylaspartate; Neurons, Afferent; Neuropeptide Y; Reflex; Spinal Cord; Substance P; Swimming; Synapses | 1999 |
Activation of GABAA but not GABAB receptors in the NTSblocked bradycardia of chemoreflex in awake rats.
Topics: Animals; Baclofen; Bradycardia; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; GABA Agonists; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reflex; Solitary Nucleus | 1999 |
Dissociation of (-) baclofen-induced effects on the tail withdrawal and hindlimb flexor reflexes of chronic spinal rats.
Topics: Analgesics; Animals; Baclofen; Decerebrate State; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; Injections, Intradermal; Injections, Spinal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex | 1999 |
[Effect of baclofen on intractable hiccup].
Topics: Adult; Baclofen; Deglutition; GABA Agonists; Hiccup; Humans; Male; Reflex; Respiratory Muscles; Treatment Outcome; Vocal Cords | 2000 |
Baclofen-induced cough suppression in cervical spinal cord injury.
Topics: Adult; Baclofen; Cough; GABA Agonists; Humans; Male; Middle Aged; Prospective Studies; Reflex; Spinal Cord Injuries | 2000 |
Pentobarbital-induced modulation of flexor and H-reflexes in spinal rats.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Electric Stimulation; H-Reflex; Male; Muscle Relaxants, Central; Pentobarbital; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord Injuries | 2000 |
Lack of sex-related differences in the prevention by baclofen of the morphine withdrawal syndrome in mice.
Topics: Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Defecation; Estrus; Female; GABA Agonists; Male; Mice; Morphine; Morphine Dependence; Reflex; Sex Characteristics; Substance Withdrawal Syndrome | 2001 |
Selective breeding of two rat lines differing in sensitivity to GHB and baclofen.
Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Animals; Baclofen; Breeding; Drug Resistance; Female; GABA Agonists; GABA-B Receptor Agonists; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, GABA-B; Reflex; Sodium Oxybate | 2001 |
Mechanisms of reflexes induced by esophageal distension.
Topics: Afferent Pathways; Animals; Baclofen; Cats; Decerebrate State; Electromyography; Esophagogastric Junction; Esophagus; Female; Insufflation; Male; Mucous Membrane; Muscle Contraction; Muscle Relaxants, Central; Peristalsis; Pharyngeal Muscles; Reflex; Stress, Mechanical; Time Factors | 2001 |
Role of GABA(B) receptors in the sedative/hypnotic effect of gamma-hydroxybutyric acid.
Topics: Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hydroxybutyrates; Hypnotics and Sedatives; Male; Mice; Mice, Inbred DBA; Morpholines; Receptors, GABA-B; Reflex | 2001 |
[The effects of intrathecally administered baclofen on somato-sympathetic reflex potentials].
Topics: Analgesics; Animals; Baclofen; Blood Pressure; Cats; Evoked Potentials, Somatosensory; Heart Rate; Injections, Spinal; Muscle Relaxants, Central; Reflex | 2002 |
The influence of baclofen on reflex circulatory reactions evoked by stimulation of the vagus nerve in the rabbit.
Topics: Afferent Pathways; Animals; Autonomic Nervous System; Baclofen; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Electric Stimulation; Female; GABA Agonists; Heart Rate; Hemodynamics; Male; Rabbits; Receptors, GABA-B; Reflex; Solitary Nucleus; Vagus Nerve | 2002 |
Suppression of GABA(B) receptor function in vivo by disulfide reducing agent, DL-dithiothreitol (DTT).
Topics: Animals; Baclofen; Conditioning, Operant; Discrimination Learning; Dithiothreitol; Drug Interactions; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Mice; Mice, Inbred DBA; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Long-Evans; Reflex | 2004 |
GABA(B) receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; GABA Agonists; GABA-B Receptor Agonists; Hypnotics and Sedatives; Male; Mice; Mice, Inbred C57BL; Motor Activity; Organophosphorus Compounds; Receptors, GABA-B; Reflex; Self Administration | 2004 |
Effects of baclofen on spinal reflexes and persistent inward currents in motoneurons of chronic spinal rats with spasticity.
Topics: Acute Disease; Animals; Baclofen; Chronic Disease; Excitatory Postsynaptic Potentials; Female; GABA Agonists; Motor Neurons; Muscle Spasticity; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord; Spinal Cord Injuries; Synapses | 2004 |
Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).
Topics: Analysis of Variance; Animals; Antiemetics; Antitussive Agents; Baclofen; Cevanes; Codeine; Copper Sulfate; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Motion Sickness; Nicotine; Reflex; Scopolamine; Shrews; Vomiting | 2007 |
Swallowing disorder and inhibition of cough reflex induced by atropine sulfate in conscious dogs.
Topics: Animals; Atropine; Baclofen; Cough; Deglutition Disorders; Dogs; Female; Male; Parasympatholytics; Pneumonia, Aspiration; Reflex | 2008 |
Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit.
Topics: Animals; Antitussive Agents; Baclofen; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naloxone; Neurokinin A; Organophosphorus Compounds; Peptide Fragments; Piperidines; Rabbits; Reflex; Solitary Nucleus | 2008 |
Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors.
Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Baclofen; Benzofurans; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; GABA Agonists; GTP-Binding Protein gamma Subunits; Humans; Male; Mice; Mice, Inbred DBA; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-B; Reflex; Stereoisomerism | 2008 |
Regulation of cardiac sympathetic afferent reflex by GABA(A) and GABA(B) receptors in paraventricular nucleus in rats.
Topics: Animals; Baclofen; Bradykinin; Capsaicin; GABA Agonists; GABA Antagonists; Heart; Isonicotinic Acids; Kidney; Male; Neurons, Afferent; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reflex; Sensory System Agents; Sympathetic Nervous System; Vigabatrin | 2008 |
Brainstem reflexes are enhanced following severe spinal cord injury and reduced by continuous intrathecal baclofen.
Topics: Adult; Area Under Curve; Baclofen; Brain Stem; Electromyography; Female; GABA Agonists; Humans; Injections, Spinal; Male; Middle Aged; Reflex; Spinal Cord Injuries; Time Factors; Young Adult | 2009 |
The occurrence of the Babinski sign in complete spinal cord injury.
Topics: Adult; Aged; Aged, 80 and over; Baclofen; Chronic Disease; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Peripheral Nervous System Diseases; Reflex; Spinal Cord Injuries; Tendons; Time Factors; Young Adult | 2010 |
Type B GABA receptors contribute to the restoration of balance during vestibular compensation in mice.
Topics: Adaptation, Physiological; Animals; Ataxia; Baclofen; Benzoates; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Lameness, Animal; Male; Mice; Mice, Inbred C57BL; Phenols; Phosphinic Acids; Postural Balance; Receptors, GABA-B; Recovery of Function; Reflex; Vestibular Nucleus, Lateral; Vestibule, Labyrinth | 2010 |
Depression of cough reflex by microinjections of antitussive agents into caudal ventral respiratory group of the rabbit.
Topics: Abdominal Muscles; Animals; Antitussive Agents; Baclofen; Cough; Diaphragm; Electromyography; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hemodynamics; Male; Microinjections; Neurokinin A; Peptide Fragments; Phrenic Nerve; Physical Stimulation; Piperidines; Rabbits; Reflex; Respiratory Center; Respiratory Mechanics; Solitary Nucleus | 2010 |
Oral baclofen reduces visceral pain-related pseudo-affective responses to colorectal distension in rats: relation between plasma exposure and efficacy.
Topics: Abdominal Pain; Administration, Oral; Animals; Baclofen; Blood Pressure; Cardiovascular System; Colon; Dilatation, Pathologic; Female; GABA-B Receptor Agonists; Heart Rate; Irritable Bowel Syndrome; Nerve Fibers; Rats; Rats, Sprague-Dawley; Reflex; Treatment Outcome; Viscera | 2011 |
Trigemino-cervical reflex in spinal cord injury.
Topics: Adult; Baclofen; Case-Control Studies; Electric Stimulation; Female; GABA Agonists; Humans; Male; Middle Aged; Muscle, Skeletal; Neck; Reflex; Spinal Cord; Spinal Cord Injuries; Trigeminal Nerve | 2014 |
Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal cord injury in rat spinal cord.
Topics: Animals; Baclofen; Enzyme Inhibitors; GABA-B Receptor Agonists; Hot Temperature; Male; Motor Neurons; Nitric Oxide Synthase Type I; Pain Perception; Rats; Rats, Wistar; Reaction Time; Reflex; Spinal Cord Injuries | 2015 |
Constitutive activity of 5-HT
Topics: Animals; Baclofen; Female; Fluoxetine; Mice; Motor Neurons; Muscle Relaxants, Central; Receptor, Serotonin, 5-HT2C; Reflex; Selective Serotonin Reuptake Inhibitors; Spinal Cord Injuries | 2017 |
Modulation of Cough Reflex by Gaba-Ergic Inhibition in Medullary Raphé of the Cat.
Topics: Animals; Baclofen; Cats; Cough; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Medulla Oblongata; Muscimol; Raphe Nuclei; Receptors, GABA-A; Receptors, GABA-B; Reflex | 2020 |