fomepizole and warfarin

fomepizole has been researched along with warfarin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cederbaum, AI; Feierman, DE; Krikun, G1
Ding, X; Gonzalez, FJ; Liu, C; Zhuo, X1
Hollenberg, PF; Lin, HL; Roberts, ES1
Gottesdiener, KM; Kari, PP; Marbury, T; Miller, JL; Mistry, GC; Rodrigues, AD; Simpson, RC; Wagner, JA; Winchell, GA1

Reviews

1 review(s) available for fomepizole and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for fomepizole and warfarin

ArticleYear
The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:6

    Topics: Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adult; Area Under Curve; Carbon Radioisotopes; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fomepizole; Half-Life; Humans; Ketoconazole; Male; Microsomes, Liver; Pyrazoles; Pyrimidinones; Quinidine; Receptors, Adrenergic, alpha-1; Sulfaphenazole; Theophylline

2005

Other Studies

4 other study(ies) available for fomepizole and warfarin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Butanols; Coumarins; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethanol; Fomepizole; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Pharmaceutical Preparations; Pyrazoles; Rats; Rats, Inbred Strains; Sodium Dodecyl Sulfate; Stereoisomerism

1986
Baculovirus-mediated expression and characterization of rat CYP2A3 and human CYP2a6: role in metabolic activation of nasal toxicants.
    Molecular pharmacology, 1996, Volume: 50, Issue:4

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Biotransformation; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Fomepizole; Hempa; Humans; Immunoblotting; Male; Methoxsalen; Metyrapone; Mixed Function Oxygenases; Nitriles; Nitrophenols; Olfactory Mucosa; Pyrazoles; Rabbits; Rats; Rats, Wistar; Spodoptera; Substrate Specificity; Testosterone

1996
Heterologous expression of rat P450 2E1 in a mammalian cell line: in situ metabolism and cytotoxicity of N-nitrosodimethylamine.
    Carcinogenesis, 1998, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Blotting, Western; Buthionine Sulfoximine; Cell Line; Cell Survival; Coumarins; Cyclic N-Oxides; Cytochrome P-450 CYP2E1; Dinitrochlorobenzene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Fibroblasts; Fomepizole; Glutathione Transferase; Humans; Indicators and Reagents; Isoniazid; Nitrogen Oxides; Nitrophenols; Nitroso Compounds; Pyrazoles; Rats; Spin Labels; Time Factors; Transfection

1998