fomepizole and sodium oxybate

fomepizole has been researched along with sodium oxybate in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Desai, MC; Maher, TJ; Quang, LS; Shannon, MW; Woolf, AD	1
Böhlke, M; Kapadia, R; Maher, TJ	1
Benowitz, NL; Dempsey, DA; Gugelmann, H; Havel, C; Jacob, P; Liakoni, E; Wiegand, TJ	1

Trials

1 trial(s) available for fomepizole and sodium oxybate

Article	Year
Butanediol Conversion to Gamma-Hydroxybutyrate Markedly Reduced by the Alcohol Dehydrogenase Blocker Fomepizole. Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:5 Topics: Adult; Alcohol Dehydrogenase; Butylene Glycols; Cross-Over Studies; Double-Blind Method; Drug Monitoring; Enzyme Inhibitors; Fomepizole; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Psychotropic Drugs; Sodium Oxybate; Solvents; Treatment Outcome	2019

Article

Year

Butanediol Conversion to Gamma-Hydroxybutyrate Markedly Reduced by the Alcohol Dehydrogenase Blocker Fomepizole.

Clinical pharmacology and therapeutics, 2019, Volume: 105, Issue:5

Topics: Adult; Alcohol Dehydrogenase; Butylene Glycols; Cross-Over Studies; Double-Blind Method; Drug Monitoring; Enzyme Inhibitors; Fomepizole; Healthy Volunteers; Humans; Male; Metabolic Clearance Rate; Psychotropic Drugs; Sodium Oxybate; Solvents; Treatment Outcome

2019

Other Studies

2 other study(ies) available for fomepizole and sodium oxybate

Article	Year
Pretreatment of CD-1 mice with 4-methylpyrazole blocks toxicity from the gamma-hydroxybutyrate precursor, 1,4-butanediol. Life sciences, 2002, Jul-05, Volume: 71, Issue:7 Topics: Alcohol Dehydrogenase; Animals; Antidotes; Biotransformation; Butylene Glycols; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fomepizole; Male; Mice; Postural Balance; Pyrazoles; Sodium Oxybate	2002
Detection of gamma-hydroxybutyrate in striatal microdialysates following peripheral 1,4-butanediol administration in rats. Life sciences, 2007, Feb-20, Volume: 80, Issue:11 Topics: Adjuvants, Anesthesia; Animals; Antidotes; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Antagonism; Fomepizole; Illicit Drugs; Injections, Intraperitoneal; Male; Microdialysis; Pyrazoles; Rats; Rats, Sprague-Dawley; Sleep; Sodium Oxybate; Spectrophotometry, Ultraviolet	2007

Article

Year

Pretreatment of CD-1 mice with 4-methylpyrazole blocks toxicity from the gamma-hydroxybutyrate precursor, 1,4-butanediol.

Life sciences, 2002, Jul-05, Volume: 71, Issue:7

Topics: Alcohol Dehydrogenase; Animals; Antidotes; Biotransformation; Butylene Glycols; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fomepizole; Male; Mice; Postural Balance; Pyrazoles; Sodium Oxybate

2002

Detection of gamma-hydroxybutyrate in striatal microdialysates following peripheral 1,4-butanediol administration in rats.

Life sciences, 2007, Feb-20, Volume: 80, Issue:11

Topics: Adjuvants, Anesthesia; Animals; Antidotes; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Antagonism; Fomepizole; Illicit Drugs; Injections, Intraperitoneal; Male; Microdialysis; Pyrazoles; Rats; Rats, Sprague-Dawley; Sleep; Sodium Oxybate; Spectrophotometry, Ultraviolet

2007