fomepizole has been researched along with methanol in 101 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (6.93) | 18.7374 |
1990's | 10 (9.90) | 18.2507 |
2000's | 44 (43.56) | 29.6817 |
2010's | 31 (30.69) | 24.3611 |
2020's | 9 (8.91) | 2.80 |
Authors | Studies |
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Blomstrand, R; Jacobsen, D; McMartin, KE; Sebastian, CS | 1 |
Jeganathan, PS; Namasivayam, A | 1 |
Ingemansson, SO | 1 |
Blomstrand, R; Hedström, CG; Ingemansson, SO; Jensen, M | 1 |
Blomstrand, R; Ingemansson, SO | 1 |
Collins, TD; Hewlett, TP; McMartin, KE | 1 |
Collins, TD; McMartin, KE | 1 |
Bolon, B; Dorman, DC; Elswick, B; LaPerle, KM; Struve, MF; Welsch, F; Wong, BA | 1 |
Jacobsen, D; McMartin, K | 1 |
Barron, SK; Breau, RL; Dies, DF; Jacobsen, D; McMartin, KE; Sebastian, CS; Spann, EG | 1 |
Hollenberg, MD; Zheng, XL | 1 |
Aaron, CK; Brent, J; Burns, MJ; Graudins, A; McMartin, K | 1 |
Shannon, M | 1 |
Dawidek-Pietryka, K; Dudka, J; Mazur, M; Szczepaniak, S | 1 |
Brau, M; Hantson, P; Haufroid, V; Mahieu, P; Vanbinst, R; Wallemacq, P | 1 |
Bonmarchand, G; Callonnec, F; Droy, JM; Girault, C; Leroy, J; Moritz, F; Tamion, F | 1 |
Ferrandière, M; Hazouard, E; Paintaud, G; Perrotin, D | 1 |
Casavant, MJ | 1 |
Aaron, C; Brent, J; Kulig, K; McMartin, K; Phillips, S | 1 |
Astier, A; Baud, FJ; Bekka, R; Bismuth, C; Borron, SW; Sandouk, P | 1 |
Eriksson, CJ; Sarkola, T | 1 |
Baud, FJ; Bismuth, C; Borron, SW; Hantson, P; Jaeger, A; Krencker, E; Mégarbane, B; Trout, H | 1 |
Persson, H | 1 |
Boyer, EW; Brown, MJ; Shannon, MW; Woolf, A | 1 |
Aaron, CK; Brent, J; Burns, MJ; McMartin, KE; Sivilotti, ML | 1 |
Barceloux, DG; Bond, GR; Cooper, H; Krenzelok, EP; Vale, JA | 1 |
Essama Mbia, JJ; Guérit, JM; Hantson, P; Haufroid, V | 1 |
Kulstad, E; Roth, B; Shepherd, G; Velez, LI | 1 |
Harris, CR; Holger, JS; Lushine, KA | 1 |
Dart, RC; Kostic, MA | 1 |
Detaille, T; Di Fazio, V; Hantson, P; Haufroid, V; König, J; Vanbinst, R; Wallemacq, PE | 1 |
Burdan, F; Dudka, J; Klepacz, R; Korobowicz, A; Korobowicz, E | 1 |
Curry, SC; Katz, KD; Ruha, AM | 1 |
Beuler, MC; Curry, SC; LoVecchio, F; Sawyers, B; Thole, D; Winchell, J | 1 |
De Brabander, N; De Decker, K; De Weerdt, A; Jorens, PG; Wojciechowski, M | 1 |
Baud, FJ; Borron, SW; Mégarbane, B | 1 |
Hori, Y; Iwasaki, Y | 1 |
Burdan, F; Dudka, J; Klepacz, R; Korobowicz, E; Madej, B; Tokarska, E | 1 |
Dunlop, O; Hovda, KE; Hunderi, OH; Jacobsen, D; Rudberg, N; Tafjord, AB | 1 |
Andersson, KS; Hovda, KE; Jacobsen, D; Urdal, P | 1 |
Froyshov, S; Gudmundsdottir, H; Hovda, KE; Jacobsen, D; Rudberg, N | 1 |
Dudka, J | 1 |
Liebelt, EL; White, ML | 1 |
Hantson, PE | 1 |
Akhtar, J; Leonard, CP | 1 |
Green, R | 1 |
Anseeuw, K; Legrand, A; Sabbe, MB | 1 |
Bajwa, M; Itagaki, B; Kraut, JA; Rastogi, A | 1 |
Brignall, JL; Daws, DE; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG | 1 |
Baud, FJ; Houzé, P; Mégarbane, B | 1 |
Hovda, KE; Jacobsen, D | 1 |
Sivilotti, ML | 1 |
Bestic, M; Blackford, M; Reed, M | 1 |
Green, AS; Wallace, EA | 1 |
Berberet, B; Breier, C; Burda, A; Lodolce, AE | 1 |
Babu, KM; Boyer, EW; Rosenbaum, CD | 1 |
Brent, J | 2 |
Garza-Ocañas, L; González-Santiago, O | 1 |
Beasley, DM; Schep, LJ; Slaughter, RJ; Vale, JA | 1 |
Badillo, RB; Schaeffer, S | 1 |
Attalla, SM; El-Bakary, AA; El-Dakrory, SA; Hasanein, NA; Malek, HA | 1 |
Aksoy, N; Atessahin, A; Baba, F; Koksal, M; Kurcer, MA; Kurcer, Z; Ocak, AR; Sahna, E | 1 |
McMartin, KE | 1 |
Chi, YC; Lee, SL; Li, YP; Shih, HT; Yin, SJ | 1 |
Sanaei-Zadeh, H; Shahmohammadi, F; Zamani, N | 1 |
Baker, JL; Daws, DE; Dewitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG | 1 |
Afshari, R; Brahmi, N; Hassanian-Moghaddam, H; Hovda, KE; Jacobsen, D; Paasma, R; Sandvik, L | 1 |
Ikäheimo, R; Lapatto-Reiniluoto, O | 1 |
Arı, S; Caça, I; Cınar, Y; Cingü, AK; Gökalp, O; Kaya, S; Sahin, A; Sahin, M; Türkcü, FM; Türkcü, G; Yüksel, H | 1 |
Bryant, SM; Lim, CS; Wahl, MS | 1 |
Chen, TH; Huang, CT; Kuo, CH; Wang, WL | 1 |
de Lange, DW; Meulenbelt, J; Rietjens, SJ | 1 |
Diblik, P; Fenclova, Z; Hovda, KE; Hubacek, JA; Klempir, J; Komarc, M; Kotikova, K; Kuthan, P; Miovsky, M; Navratil, T; Nurieva, O; Pelclova, D; Petrik, V; Pilin, A; Ridzon, P; Rulisek, J; Seidl, Z; Urban, P; Vaneckova, M; Zakharov, S | 1 |
Navratil, T; Pelclova, D; Zakharov, S | 1 |
Kurcova, I; Navratil, T; Pelclova, D; Salek, T; Zakharov, S | 1 |
Belacek, J; Eddleston, M; Hovda, KE; Komarc, M; Navratil, T; Pelclova, D; Zakharov, S | 1 |
Kraut, JA | 1 |
Aksu, N; Anil, AB; Anil, M; Bal, A; Can, FK; Gokalp, G; Sahbudak Bal, Z; Yavascan, O | 1 |
Hovda, KE; Jacobsen, D; McMartin, K | 1 |
Bradberry, SM; Davies, J; Eddleston, M; Gilfillan, C; Jackson, G; Thanacoody, RH; Thomas, SH; Thompson, JP; Vale, AJ | 1 |
Fralick, M; Himmel, ME; Lam, K | 1 |
Kiyota, K | 1 |
Gromov, MS; Maslyakov, VV; Zabrodskii, PF | 1 |
Hassanian-Moghaddam, H; Zamani, N | 1 |
Collister, D; Duff, G; Hingwala, J; Komenda, P; Palatnick, W; Tangri, N | 1 |
Balik, M; Belohlavek, J; Pelclova, D; Polak, F; Rulisek, J; Waldauf, P; Zakharov, S | 1 |
Beauchamp, GA; Kim, J; Valento, M | 1 |
Davis, WT; Koyfman, A; Long, BJ; Ng, PCY; Sessions, DJ | 1 |
Gau, N; Scott, MG | 1 |
Bayasi, G; Beattie, C; Beattie, M; Morrison, ED | 1 |
Cervantes, CE; Chu, A; Heller, D; Lemont, M | 1 |
Hassanian-Moghaddam, H; Mégarbane, B | 1 |
Leonard, JB; Minhaj, FS | 1 |
Jones, AW | 1 |
Foreid, S; Froeyshov, S; Holm, P; Hovda, KE; Jacobsen, D; Kvaerner, C; Lao, YE; Latimer, B; Mataric, M; McMartin, K; Vartdal, T | 1 |
Brent, J; McMartin, K | 1 |
Maliakkal, J; McEnery, B; Scalzo, A | 1 |
Inman, B; Koyfman, A; Long, B; Maddry, JK; Ng, PC | 1 |
Akpunonu, P; Johnson, E; Kalani, M; Maskey, A; McCoy, A; Mefford, B; Micciche, A | 1 |
24 review(s) available for fomepizole and methanol
Article | Year |
---|---|
Methanol toxicity. Agency for Toxic Substances and Disease Registry.
Topics: Acute Disease; Aged; Chronic Disease; Clinical Protocols; Environmental Exposure; Ethanol; Family Practice; Folic Acid; Fomepizole; Humans; Male; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Risk Factors | 1993 |
American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning.
Topics: Ethanol; Fomepizole; Formates; Humans; Leucovorin; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Renal Dialysis | 2002 |
Rethinking the toxic methanol level.
Topics: Acidosis; Adolescent; Adult; Antidotes; Bicarbonates; Child, Preschool; Dose-Response Relationship, Drug; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Pyrazoles; Treatment Outcome | 2003 |
Fomepizole as a therapeutic strategy in paediatric methanol poisoning. A case report and review of the literature.
Topics: Antidotes; Child, Preschool; Drug Therapy, Combination; Fomepizole; Humans; Leucovorin; Male; Methanol; Poisoning; Pyrazoles; Solvents | 2005 |
Current recommendations for treatment of severe toxic alcohol poisonings.
Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 2005 |
[Practical analysis of toxic substances useful for clinical toxicology-12-methanol].
Topics: Adult; Biomarkers; Chromates; Colorimetry; Ethanol; Fomepizole; Formates; Gas Chromatography-Mass Spectrometry; Humans; Infusions, Intravenous; Male; Methanol; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Specimen Handling | 2004 |
Update on antidotes for pediatric poisoning.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Antidotes; Antivenins; Child; Child, Preschool; Cholinergic Antagonists; Cholinesterase Inhibitors; Crotalid Venoms; Emergencies; Ethylene Glycol; Female; Fomepizole; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Infant; Infusions, Intravenous; Injections, Intramuscular; Male; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Snake Bites; Syringes | 2006 |
[Acute methanol intoxication: physiopathology, prognosis and treatment].
Topics: Acidosis; Acute Disease; Antidotes; Central Nervous System; Fomepizole; Formaldehyde; Humans; Liver; Methanol; Poisoning; Prognosis; Pyrazoles; Renal Dialysis; Visual Pathways | 2006 |
Expert opinion: fomepizole may ameliorate the need for hemodialysis in methanol poisoning.
Topics: Acidosis; Antidotes; Bicarbonates; Drug Therapy, Combination; Fomepizole; Humans; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Renal Dialysis; Solvents; Triage | 2008 |
Fomepizole: a critical assessment of current dosing recommendations.
Topics: Adult; Alcohol Dehydrogenase; Animals; Antidotes; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles | 2009 |
Fomepizole for ethylene glycol and methanol poisoning.
Topics: Acidosis; Adult; Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Methanol; Osmolar Concentration; Poisoning; Practice Guidelines as Topic; Pyrazoles; Suicide, Attempted | 2009 |
Poison control therapy.
Topics: Anesthetics, Local; Antidotes; Antivenins; Calcium Channel Blockers; Child, Preschool; Cyanides; Emergency Treatment; Fat Emulsions, Intravenous; Fomepizole; Humans; Hydroxocobalamin; Hypoglycemic Agents; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Insulin; Male; Methanol; Middle Aged; Poison Control Centers; Poisoning; Pyrazoles; Snake Bites; Vitamin B Complex | 2009 |
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene Glycol; Ethylene Glycols; Ethylenes; Fomepizole; Glycols; Humans; Male; Methanol; Pediatrics; Pyrazoles; Renal Dialysis | 2010 |
[Surrogate alcohol poisonings].
Topics: Acidosis; Antidotes; Ethylene Glycol; Finland; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis | 2012 |
Use of Fomepizole in Pediatric Methanol Exposure: The First Case Report in Taiwan and a Literature Review.
Topics: Antidotes; Fomepizole; Humans; Infant; Male; Methanol; Pyrazoles; Taiwan | 2016 |
Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?
Topics: Animals; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Solvents | 2014 |
Diagnosis of toxic alcohols: limitations of present methods.
Topics: Acid-Base Equilibrium; Acidosis; Alcohols; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Osmolar Concentration; Propylene Glycol; Pyrazoles | 2015 |
Antidotes for poisoning by alcohols that form toxic metabolites.
Topics: Acidosis; Antidotes; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles | 2016 |
[Antidote update].
Topics: Alcohol Dehydrogenase; Antidotes; Ethylene Glycol; Fomepizole; Humans; Japan; Methanol; Methemoglobinemia; Methylene Blue; Pyrazoles | 2016 |
A Brief Review on Toxic Alcohols: Management Strategies.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Solvents | 2016 |
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Propylene Glycol; Pyrazoles; Renal Dialysis | 2016 |
Toxic alcohol diagnosis and management: an emergency medicine review.
Topics: 2-Propanol; Alcohol Drinking; Alcohols; Antidotes; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 2018 |
Clinical and forensic toxicology of methanol.
Topics: Aged; Antidotes; Ethanol; Fomepizole; Forensic Toxicology; Humans; Male; Methanol | 2021 |
High risk and low prevalence diseases: Toxic alcohol ingestion.
Topics: Acidosis; Eating; Ethanol; Fomepizole; Humans; Methanol; Prevalence | 2023 |
6 trial(s) available for fomepizole and methanol
Article | Year |
---|---|
4-Methylpyrazole: a controlled study of safety in healthy human subjects after single, ascending doses.
Topics: Adult; Alcohol Dehydrogenase; Dizziness; Double-Blind Method; Drug Evaluation; Drug Tolerance; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Nausea; Pyrazoles; Safety | 1988 |
Kinetic interactions between 4-methylpyrazole and ethanol in healthy humans.
Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Metabolic Clearance Rate; Methanol; Pyrazoles | 1996 |
Fomepizole for the treatment of methanol poisoning.
Topics: Acidosis; Adolescent; Adult; Alcohol Dehydrogenase; Antidotes; Enzyme Inhibitors; Female; Fomepizole; Formates; Humans; Injections, Intravenous; Male; Methanol; Middle Aged; Poisoning; Prospective Studies; Pyrazoles | 2001 |
Effect of 4-methylpyrazole on endogenous plasma ethanol and methanol levels in humans.
Topics: Adult; Alcohol Dehydrogenase; Analysis of Variance; Antidotes; Cross-Over Studies; Double-Blind Method; Ethanol; Female; Fomepizole; Humans; Liver; Male; Methanol; Pyrazoles; Regression Analysis | 2001 |
Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning.
Topics: Administration, Oral; Adult; Antidotes; Chromatography, Gas; Dose-Response Relationship, Drug; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Infant; Injections, Intravenous; Liver; Male; Metabolic Clearance Rate; Methanol; Poisoning; Pyrazoles; Tissue Distribution | 2004 |
Analysis of Fomepizole Elimination in Methanol- and Ethylene Glycol-Poisoned Patients.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisons; Pyrazoles | 2022 |
71 other study(ies) available for fomepizole and methanol
Article | Year |
---|---|
Role of acidosis in the changes of rat brain monoamines after methanol administration & effect of blocking methanol metabolism by 4-methyl pyrazole & 3-amino-1,2,4-triazole.
Topics: Acidosis; Amitrole; Animals; Brain Chemistry; Catecholamines; Fomepizole; Methanol; Pyrazoles; Rats; Rats, Inbred Strains; Serotonin; Triazoles | 1988 |
Studies on the effect of 4-methylpyrazole on retinal activity in the methanol poisoned monkey by recording the electroretinogram.
Topics: Animals; Antidotes; Chlorocebus aethiops; Electroretinography; Fomepizole; Macaca fascicularis; Male; Methanol; Pyrazoles; Retina | 1983 |
Normal electroretinogram and no toxicity signs after chronic and acute administration of the alcohol dehydrogenase inhibitor 4-methylpyrazole to the cynomolgus monkey (Macaca fascicularis)--a possible new treatment of methanol poisoning.
Topics: Alcohol Oxidoreductases; Animals; Electroretinography; Fomepizole; Macaca fascicularis; Male; Methanol; Pyrazoles; Retina; Time Factors | 1984 |
Studies on the effect of 4-methylpyrazole on methanol poisoning using the monkey as an animal model: with particular reference to the ocular toxicity.
Topics: Alcohol Oxidoreductases; Animals; Disease Models, Animal; Disease Susceptibility; Eye; Fomepizole; Macaca fascicularis; Male; Methanol; Pyrazoles; Vision, Ocular | 1984 |
High pressure liquid chromatographic assay of 4-methylpyrazole. Measurements of plasma and urine levels.
Topics: Absorption; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Fomepizole; Methanol; Pyrazoles; Rats; Rats, Inbred Strains | 1984 |
Role of ethanol metabolism in the alcohol-induced increase in urinary folate excretion in rats.
Topics: Animals; Diuresis; Ethanol; Folic Acid; Fomepizole; Kinetics; Male; Methanol; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
Role of formate in methanol-induced exencephaly in CD-1 mice.
Topics: Animals; Decidua; Embryonic and Fetal Development; Erythrocyte Count; Female; Fomepizole; Formates; In Vitro Techniques; Methanol; Mice; Neural Tube Defects; Pregnancy; Pyrazoles; Rats; Teratogens | 1995 |
4-Methylpyrazole--present status.
Topics: Animals; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 1996 |
Tyrosine kinase inhibitor-sensitive contractile action of ethanol in gastric smooth muscle: comparison with the action of epidermal growth factor.
Topics: 1-Propanol; Animals; Calcium; Catechols; Cyclohexanones; Enzyme Inhibitors; Epidermal Growth Factor; Ethanol; Fomepizole; Genistein; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Male; Maleimides; Methanol; Muscle Contraction; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyrazoles; Quinazolines; Signal Transduction; Stomach; Tyrphostins | 1997 |
Treatment of methanol poisoning with intravenous 4-methylpyrazole.
Topics: Adult; Alcohol Dehydrogenase; Enzyme Inhibitors; Fomepizole; Humans; Infusions, Intravenous; Male; Methanol; Poisoning; Pyrazoles | 1997 |
Toxicology reviews: fomepizole--a new antidote.
Topics: Antidotes; Child; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles | 1998 |
In vitro studies of human alcohol dehydrogenase inhibition in the process of methanol and ethylene glycol oxidation.
Topics: Alcohol Dehydrogenase; Cimetidine; Enzyme Inhibitors; Ethylene Glycol; Fomepizole; Humans; In Vitro Techniques; Liver; Methanol; Methylene Blue; Pyrazoles; Theophylline | 1998 |
Two cases of acute methanol poisoning partially treated by oral 4-methylpyrazole.
Topics: Administration, Oral; Adolescent; Antidotes; Ethanol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning; Pyrazoles | 1999 |
Fomepizole (4-methylpyrazole) in fatal methanol poisoning with early CT scan cerebral lesions.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Antidotes; Brain; Coma; Dialysis; Enzyme Inhibitors; Fatal Outcome; Female; Fomepizole; Humans; Methanol; Pyrazoles; Suicide, Attempted; Tomography, X-Ray Computed | 1999 |
Delayed toxicity in acute ethanol-methanol copoisoning in a chronic alcohol abuser: usefulness of continuous 4-methylpyrazole (fomepizole) infusion.
Topics: Antidotes; Ethanol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2000 |
Fomepizole in the treatment of poisoning.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Child; Drug Costs; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2001 |
Treatment of methanol and isopropanol poisoning with intravenous fomepizole.
Topics: 2-Propanol; Adult; Antidotes; Chromatography, Gas; Fomepizole; Half-Life; Humans; Male; Metabolic Clearance Rate; Methanol; Pyrazoles; Suicide, Attempted | 2001 |
Treatment of acute methanol poisoning with fomepizole.
Topics: Adolescent; Adult; Alcohol Dehydrogenase; Antidotes; Consumer Product Safety; Female; Fomepizole; Half-Life; Humans; Male; Methanol; Middle Aged; Pyrazoles; Renal Dialysis; Retrospective Studies; Statistics, Nonparametric; Vision Disorders | 2001 |
[Ethylene glycol and methanol poisoning. Fomepizole--an alternative antidote].
Topics: Adult; Antidotes; Child; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles | 2001 |
Childhood methanol ingestion treated with fomepizole and hemodialysis.
Topics: Adult; Antidotes; Child, Preschool; Fomepizole; Humans; Male; Methanol; Poisoning; Pyrazoles; Renal Dialysis | 2001 |
Reversal of severe methanol-induced visual impairment: no evidence of retinal toxicity due to fomepizole.
Topics: Adult; Antidotes; Buffers; Central Nervous System Depressants; Ethanol; Fomepizole; Humans; Male; Methanol; Pyrazoles; Retinal Diseases; Sodium Bicarbonate; Solvents; Vision Disorders | 2001 |
Fomepizole therapy for reversal of visual impairment after methanol poisoning: a case documented by visual evoked potentials investigation.
Topics: Alcohol Dehydrogenase; Antidotes; Electroretinography; Evoked Potentials, Visual; Fomepizole; Humans; Infusions, Intravenous; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Safety; Vision Disorders | 2002 |
Inhalational methanol toxicity in pregnancy treated twice with fomepizole.
Topics: Administration, Inhalation; Adult; Antidotes; Diagnosis, Differential; Emergency Treatment; Female; Fomepizole; Humans; Infusions, Intravenous; Methanol; Poisoning; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pyrazoles | 2003 |
Methanol ingestion: prevention of toxic sequelae after massive ingestion.
Topics: Adult; Alcoholic Intoxication; Antidotes; Blood Gas Analysis; Breath Tests; Combined Modality Therapy; Diagnosis, Differential; Emergency Treatment; Ethanol; Fomepizole; Humans; Male; Metabolic Clearance Rate; Methanol; Pyrazoles; Recovery of Function; Renal Dialysis; Time Factors; Treatment Outcome | 2003 |
Human skeletal muscle lactate dehydrogenase activity in the presence of some alcohol dehydrogenase inhibitors.
Topics: Alcohol Dehydrogenase; Cimetidine; Edetic Acid; Ethanol; Fomepizole; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Methanol; Pectoralis Muscles; Pyrazoles | 2004 |
Aniline and methanol toxicity after shoe dye ingestion.
Topics: Adult; Aniline Compounds; Antidotes; Coloring Agents; Emergency Medical Services; Erythrocyte Transfusion; Female; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Solvents | 2004 |
Outcomes following abuse of methanol-containing carburetor cleaners.
Topics: Acidosis; Adolescent; Adult; Antidotes; Ethanol; Female; Fluid Therapy; Fomepizole; Humans; Inhalation Exposure; Injections, Intravenous; Male; Methanol; Poisoning; Pyrazoles; Retrospective Studies; Solvents; Substance-Related Disorders; Treatment Outcome | 2004 |
[Human erythrocyte lactate dehydrogenase activity changes in the presence of some alcohol dehydrogenase inhibitors].
Topics: Adult; Alcohol Dehydrogenase; Cimetidine; Edetic Acid; Enzyme Inhibitors; Erythrocytes; Ethanol; Female; Fomepizole; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases, Alcoholic; Male; Methanol; Middle Aged; Pyrazoles; Spectrophotometry | 2004 |
Methanol outbreak in Norway 2002-2004: epidemiology, clinical features and prognostic signs.
Topics: Adult; Aged; Antidotes; Carbon Dioxide; Disease Outbreaks; Ethanol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Norway; Poisoning; Prognosis; Prospective Studies; Pyrazoles; Retrospective Studies; Vision Disorders | 2005 |
Methanol and formate kinetics during treatment with fomepizole.
Topics: Acidosis; Adult; Aged; Antidotes; Bicarbonates; Chromatography, Gas; Dialysis; Fomepizole; Formates; Half-Life; Humans; Kidney; Male; Methanol; Middle Aged; Prospective Studies; Pyrazoles | 2005 |
Fomepizole may change indication for hemodialysis in methanol poisoning: prospective study in seven cases.
Topics: Acidosis; Adult; Aged; Antidotes; Female; Follow-Up Studies; Fomepizole; Humans; Male; Methanol; Middle Aged; Prospective Studies; Pyrazoles; Renal Dialysis; Solvents; Treatment Outcome | 2005 |
The total antioxidant status in the brain after ethanol or 4-methylpyrazole administration to rats intoxicated with methanol.
Topics: Administration, Inhalation; Administration, Oral; Animals; Antioxidants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Fomepizole; Injections, Intraperitoneal; Methanol; Nitrous Oxide; Oxygen; Pyrazoles; Rats; Solvents | 2006 |
Co-ingestion of methanol and nitromethane: using falsely elevated creatinine as indicator for methanol antidote use.
Topics: Antidotes; Child, Preschool; Creatinine; False Positive Reactions; Female; Fomepizole; Humans; Intensive Care Units, Pediatric; Methane; Methanol; Nitroparaffins; Pyrazoles | 2007 |
The management of severe toxic alcohol ingestions at a tertiary care center after the introduction of fomepizole.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Databases, Factual; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Retrospective Studies; Solvents | 2007 |
Methanol poisoning: the duality between 'fast and cheap' and 'slow and expensive'.
Topics: Adult; Antidotes; Belgium; Ethanol; Female; Fomepizole; Hospital Costs; Humans; Inactivation, Metabolic; Length of Stay; Methanol; Poisoning; Pregnancy; Pregnancy Complications; Pyrazoles; Renal Dialysis | 2008 |
Spurious elevation in serum creatinine caused by ingestion of nitromethane: implication for the diagnosis and treatment of methanol intoxication.
Topics: Acidosis; Acute Kidney Injury; Adult; Creatinine; Female; Follow-Up Studies; Fomepizole; Humans; Kidney Function Tests; Methane; Methanol; Nitroparaffins; Pyrazoles; Renal Dialysis; Severity of Illness Index; Suicide, Attempted; Treatment Outcome | 2008 |
Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Cohort Studies; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Proportional Hazards Models; Pyrazoles | 2009 |
Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations.
Topics: Administration, Oral; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Intravenous; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Retrospective Studies | 2008 |
Ethanol: tastes great! Fomepizole: less filling!
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Pyrazoles | 2009 |
Methanol toxicity secondary to inhalant abuse in adult men.
Topics: Acidosis; Adult; Antidotes; Ethanol; Ethnicity; Fomepizole; Hispanic or Latino; Humans; Indians, North American; Male; Methanol; Middle Aged; Oklahoma; Poisoning; Pyrazoles; Renal Dialysis; Solvents; Substance-Related Disorders; Vision Disorders; White People; Young Adult | 2009 |
Discontinuation of 5% alcohol in 5% dextrose injection: implications for antidote stocking.
Topics: Alcohols; Antidotes; Drug Therapy, Combination; Ethylene Glycol; Fomepizole; Glucose; Humans; Illinois; Injections, Intravenous; Methanol; Pharmacy Service, Hospital; Poison Control Centers; Poisoning; Practice Guidelines as Topic; Pyrazoles | 2008 |
Head CT in patient with metabolic acidosis.
Topics: Acid-Base Imbalance; Acidosis; Adult; Alcoholism; Anisocoria; Antidotes; Bicarbonates; Cerebral Hemorrhage; Emergency Medical Services; Fatal Outcome; Female; Fomepizole; Head; Humans; Methanol; Pyrazoles; Renal Dialysis; Respiration, Artificial; Tomography, X-Ray Computed | 2008 |
Fomepizole for toxic alcohol poisoning.
Topics: Antidotes; Drug Interactions; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2009 |
A seaman with blindness and confusion.
Topics: Alcoholic Intoxication; Antidotes; Blindness; Confusion; Fomepizole; Humans; Male; Methanol; Naval Medicine; Pyrazoles | 2009 |
Ranitidine as an alcohol dehydrogenase inhibitor in acute methanol toxicity in rats.
Topics: Acidosis; Alcohol Dehydrogenase; Animals; Antidotes; Enzyme Inhibitors; Ethanol; Fomepizole; Formates; Male; Methanol; Photoreceptor Cells, Vertebrate; Pyrazoles; Random Allocation; Ranitidine; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases | 2010 |
Effect of lycopene on caspase-3 enzyme activation in liver of methanol-intoxicated rats: comparison with fomepizole.
Topics: Animals; Carotenoids; Caspase 3; Disease Models, Animal; Enzyme Activation; Female; Fomepizole; Humans; Liver; Liver Diseases, Alcoholic; Lycopene; Malondialdehyde; Methanol; Pyrazoles; Random Allocation; Rats; Rats, Wistar | 2010 |
Antidotes for alcohol and glycol toxicity: translating mechanisms into treatments.
Topics: Animals; Antidotes; Clinical Trials as Topic; Drug Design; Drug Evaluation, Preclinical; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Translational Research, Biomedical | 2010 |
Oxidation of methanol, ethylene glycol, and isopropanol with human alcohol dehydrogenases and the inhibition by ethanol and 4-methylpyrazole.
Topics: 2-Propanol; Alcohol Dehydrogenase; Enzyme Inhibitors; Ethanol; Ethylene Glycol; Fomepizole; Humans; Kinetics; Methanol; Oxidation-Reduction; Pyrazoles | 2011 |
Can fomepizole be substituted by abacavir in the treatment of methanol poisoning?
Topics: Antidotes; Dideoxynucleosides; Drug Substitution; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Solvents | 2011 |
Medication errors associated with the use of ethanol and fomepizole as antidotes for methanol and ethylene glycol poisoning.
Topics: Adult; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Medication Errors; Methanol; Middle Aged; Pyrazoles | 2011 |
Risk factors related to poor outcome after methanol poisoning and the relation between outcome and antidotes--a multicenter study.
Topics: Adolescent; Adult; Aged; Antidotes; Child; Child, Preschool; Consciousness; Ethanol; Female; Fomepizole; Humans; Hydrogen-Ion Concentration; Male; Methanol; Middle Aged; Prognosis; Pyrazoles; Retrospective Studies; Risk Assessment; Risk Factors | 2012 |
The effects of caffeic acid phenethyl ester in acute methanol toxicity on rat retina and optic nerve.
Topics: Alcohol Dehydrogenase; Animals; Antidotes; Caffeic Acids; Ethanol; Fomepizole; Humans; Male; Methanol; Molecular Docking Simulation; Optic Nerve; Oxidative Stress; Phenylethyl Alcohol; Pyrazoles; Rats; Rats, Sprague-Dawley; Retina | 2013 |
Management of unintentional methanol ingestions - kids aren't little adults?
Topics: Accidents, Home; Adolescent; Adult; Aged; Antidotes; Child; Child, Preschool; Female; Fomepizole; Humans; Infant; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Watchful Waiting; Young Adult | 2013 |
Czech mass methanol outbreak 2012: epidemiology, challenges and clinical features.
Topics: Acidosis; Adolescent; Adult; Aged; Antidotes; Biomarkers; Consciousness; Czech Republic; Disease Outbreaks; Drug Overdose; Ethanol; Female; Fomepizole; Hospital Mortality; Hospitalization; Humans; Logistic Models; Male; Mass Casualty Incidents; Methanol; Middle Aged; Multivariate Analysis; Odds Ratio; Prospective Studies; Pyrazoles; Renal Dialysis; Retrospective Studies; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome; Vision Disorders; Young Adult | 2014 |
Fomepizole in the treatment of acute methanol poisonings: experience from the Czech mass methanol outbreak 2012-2013.
Topics: Adolescent; Adult; Antidotes; Czech Republic; Disease Outbreaks; Ethanol; Female; Fomepizole; Hospital Mortality; Humans; Male; Methanol; Middle Aged; Prospective Studies; Pyrazoles; Retrospective Studies; Treatment Outcome; Young Adult | 2014 |
Fluctuations in serum ethanol concentration in the treatment of acute methanol poisoning: a prospective study of 21 patients.
Topics: Adult; Aged; Antidotes; Drug Therapy, Combination; Ethanol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Prospective Studies; Pyrazoles; Treatment Outcome | 2015 |
Fomepizole versus ethanol in the treatment of acute methanol poisoning: Comparison of clinical effectiveness in a mass poisoning outbreak.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Antidotes; Chi-Square Distribution; Cross-Sectional Studies; Czech Republic; Disease Outbreaks; Drug Administration Schedule; Ethanol; Female; Fomepizole; Hospitalization; Humans; Intensive Care Units; Length of Stay; Linear Models; Logistic Models; Male; Methanol; Middle Aged; Multivariate Analysis; Poisoning; Pyrazoles; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Young Adult | 2015 |
A Rare Cause of Metabolic Acidosis: Fatal Transdermal Methanol Intoxication in an Infant.
Topics: Acidosis; Antidotes; Fatal Outcome; Female; Fomepizole; Humans; Infant; Methanol; Pyrazoles; Renal Dialysis; Subarachnoid Hemorrhage | 2016 |
Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS).
Topics: Adult; Antidotes; Disease Management; Ethanol; Ethylene Glycol; Fomepizole; Hospitalization; Humans; Methanol; Middle Aged; Poisoning; Prognosis; Prospective Studies; Pyrazoles; United Kingdom; Young Adult | 2016 |
Hemodialysis in a Healthy Patient--A Case of an Erroneous Laboratory Result: A Teachable Moment.
Topics: Acidosis; Alcoholism; Antidotes; Diagnostic Errors; Female; Fomepizole; Humans; Medical Errors; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Solvents; Truth Disclosure | 2016 |
[EFFECT OF 4-METHYLPYRAZOLE ON IMMUNE RESPONSE, FUNCTION OF Th1 AND Th2 LYMPHOCYTES, AND CYTOKINE CONCENTRATION IN RAT BLOOD AFTER ACUTE METHANOL POISONING].
Topics: Acute Disease; Animals; Animals, Outbred Strains; Antidotes; Female; Fomepizole; Immunity, Cellular; Immunity, Humoral; Interferon-gamma; Interleukin-1beta; Interleukin-2; Interleukin-4; Interleukin-6; Male; Methanol; Pyrazoles; Rats; Th1 Cells; Th1-Th2 Balance; Th2 Cells; Tumor Necrosis Factor-alpha | 2016 |
A Methanol Intoxication Outbreak From Recreational Ingestion of Fracking Fluid.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Antidotes; Disease Outbreaks; Eating; Fomepizole; Humans; Hydraulic Fracking; Leucovorin; Male; Manitoba; Methanol; Middle Aged; Nausea; Poisoning; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Solvents; Vomiting; Young Adult | 2017 |
Cost-effectiveness of hospital treatment and outcomes of acute methanol poisoning during the Czech Republic mass poisoning outbreak.
Topics: Adult; Alcoholism; Antidotes; Cost-Benefit Analysis; Cross-Sectional Studies; Czech Republic; Disease Outbreaks; Economics, Hospital; Ethanol; Female; Fomepizole; Health Care Costs; Hospital Costs; Hospitalization; Humans; Male; Methanol; Middle Aged; Poisoning; Prospective Studies; Pyrazoles; Quality of Life; Renal Dialysis; Treatment Outcome | 2017 |
Fill in the Gaps: An Unresponsive 55-Year-Old Man.
Topics: Acid-Base Equilibrium; Antidotes; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning | 2018 |
Methanol Toxicity From Occupational Exposure: A Case Report.
Topics: Adult; Diagnosis, Differential; Folic Acid; Fomepizole; Humans; Inhalation Exposure; Male; Methanol; Occupational Diseases; Occupational Exposure; Poisoning; Renal Dialysis; Skin Absorption | 2019 |
Early dialysis in a rare case of combined toxic alcohols ingestion.
Topics: Acidosis; Adult; Alcohols; Antidotes; Bicarbonates; Buffers; Combined Modality Therapy; Eating; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Renal Dialysis; Solvents; Treatment Outcome | 2020 |
Is fomepizole the antidote to recommend in mass methanol outbreaks?
Topics: Antidotes; Consensus; Disease Outbreaks; Fomepizole; Humans; Methanol | 2020 |
Evaluation of level of care for toxic alcohol ingestions receiving fomepizole.
Topics: Adult; Aged; Antidotes; Baltimore; Combined Modality Therapy; Critical Care; Ethylene Glycol; Facilities and Services Utilization; Female; Fomepizole; Humans; Intensive Care Units; Male; Methanol; Middle Aged; Retrospective Studies | 2021 |
Fomepizole dosing during continuous renal replacement therapy - an observational study.
Topics: Adult; Antidotes; Continuous Renal Replacement Therapy; Fomepizole; Humans; Methanol; Renal Dialysis; Renal Replacement Therapy | 2022 |
Methanol toxicity in a pediatric patient treated with fomepizole and hemodialysis.
Topics: Adolescent; Adult; Antidotes; Child; Fomepizole; Humans; Male; Methanol; Pyrazoles; Renal Dialysis | 2023 |
A Case of an Intraoperative Iatrogenic Methanol Exposure.
Topics: Aged; Antidotes; Dimercaprol; Female; Fomepizole; Humans; Iatrogenic Disease; Methanol; Pyrazoles | 2023 |