fomepizole and ethylene glycol

fomepizole has been researched along with ethylene glycol in 114 studies

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-19905 (4.39)18.7374
1990's22 (19.30)18.2507
2000's39 (34.21)29.6817
2010's36 (31.58)24.3611
2020's12 (10.53)2.80

Authors

AuthorsStudies
Dial, SM; Hamar, DW; Thrall, MA3
Blomstrand, R; Jacobsen, D; McMartin, KE; Sebastian, CS1
Porter, GA1
Astier, A; Baud, FJ; Bien, DV; Bismuth, C; Galliot, M; Garnier, R; Likforman, J1
Grauer, GF; Henre, BA; Hjelle, JJ; Thrall, MA1
Allain, P; Alquier, P; Bouachour, G; Harry, P; Houze, P; Turcant, A1
Allain, P; Harry, P; Jobard, E; Roy, PM; Turcant, A1
Jacobsen, D; McMartin, K1
Barron, SK; Breau, RL; Dies, DF; Jacobsen, D; McMartin, KE; Sebastian, CS; Spann, EG1
Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA1
Allain, P; Harry, P; Jobard, E; Le Bouil, A; Turcant, A1
Shannon, M1
Hantson, P; Hassoun, A; Mahieu, P1
Briand, M; Caubet, A; Harry, P; Jobard, E; Turcant, A1
Dawidek-Pietryka, K; Dudka, J; Mazur, M; Szczepaniak, S1
Weinman, SA1
Brent, J; Ford, MD; Kerns, W; McMartin, KE; Moreau, CL; Rose, SR; Tomaszewski, CA1
Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M1
Jacobsen, D1
Wiley, JF1
Baud, FJ; Borron, SW; Mégarbane, B2
Barceloux, DG; Krenzelok, EP; Olson, K; Watson, W1
Goldfarb, DS1
Lejeune, P; Piagnerelli, M; Vanhaeverbeek, M1
Brent, J; Burns, MJ; McMartin, KE; Sivilotti, ML1
Watson, WA1
Cenac, TA; McMartin, KE1
Aviles, SR; Baum, CR; Goldstein, CA; Langman, CB; Makar, JK; Oker, EE1
Casavant, MJ1
Boyer, EW; Mejia, M; Shannon, M; Woolf, A1
Benitez, JG; Krenzelok, EP; Swanson-Biearman, B1
Hertko, LJ; Korbet, SM; Leikin, JB; Najafi, CC1
Brent, J3
Persson, H1
Druteika, DP; Ensom, MH; Zed, PJ1
Battistella, M1
Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML1
Aakervik, O; Jacobsen, D; Svendsen, J1
Nicholson, WJ; Schiffman, F; Tuohy, KA1
Hellman, RN; Vasavada, N; Williams, C1
Detaille, T; Di Fazio, V; Hantson, P; Haufroid, V; König, J; Vanbinst, R; Wallemacq, PE1
Clément de Cléty, S; Dembour, G; Detaille, T; Hantson, P; Vanbinst, R; Wallemacq, P1
Caravati, EM; Heileson, HL; Jones, M1
Cox, RD; Phillips, WJ1
Brooks, DE; Pizon, AF1
Adnet, F; Amathieu, R; Borron, SW; Lapostolle, F; Merouani, M; Smail, N1
Liebelt, EL; White, ML1
Brown, DF; Nadel, ES; Tiamfook-Morgan, TO1
Gracia, R; Neerman, MF; Velez, LI1
Green, R1
Keyes, DC; Lee, YC; Shepherd, G; Velez, LI1
Brignall, JL; Brubacher, JR; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lam, GS; Lawson, EJ; Lepik, KJ; Purssell, RA1
Brignall, JL; Daws, DE; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG1
Baud, FJ; Houzé, P; Mégarbane, B1
Sivilotti, ML1
Bestic, M; Blackford, M; Reed, M1
Berberet, B; Breier, C; Burda, A; Lodolce, AE1
Al-Duaij, N; Becker, ML; Ewald, MB; George, M1
Endo, Y1
Garza-Ocañas, L; González-Santiago, O1
Akahori, F1
Alhelail, M; Brent, J; Buchanan, JA; Cetaruk, EW; Kulig, K; Palmer, RB; Schaeffer, TH1
Connally, HE; Hamar, DW; Thrall, MA1
Asif Siddiqui, OM; Luqman, A; Naseer, A; Stanifer, J; Wall, BM1
McMartin, KE1
Chi, YC; Lee, SL; Li, YP; Shih, HT; Yin, SJ1
Powell, LL; Tart, KM1
Baker, JL; Daws, DE; Dewitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG1
Brørs, O; Hovda, KE; Jacobsen, D; Julsrud, J; Øvrebø, S1
Bikin, D; Boyer, E; Burns, J; Curry, SC; Gerkin, RD; Levine, M; Pizon, AF; Ruha, AM1
Duncan, D; Hann, G; Sohi, D; Sudhir, G; West, P1
Cafferkey, M; Isse, S; Lal, A; Mangera, Z; Winnett, G1
Ikäheimo, R; Lapatto-Reiniluoto, O1
Cantrell, FL; Clark, RF; Darracq, MA; Rentmeester, LL; Schneir, AB; Tomaszewski, CA1
Kowalówka-Zawieja, J; Orłowski, J; Przystanowicz, J; Sommerfeld, K; Zielińska-Psuja, B1
Dulaney, AR; Murphy, CM; Vitto, MJ1
Ahmed, A; Engelman, A; Krasowski, MD; Tschetter, PA1
Brasiel, JA; Kearney, TE; Lung, DD; Olson, KR1
de Lange, DW; Meulenbelt, J; Rietjens, SJ1
Mégarbane, B; Résière, D1
Garg, D; Irani, M; Lim, T1
Kraut, JA1
Hovda, KE; Jacobsen, D; McMartin, K1
Bradberry, SM; Davies, J; Eddleston, M; Gilfillan, C; Jackson, G; Thanacoody, RH; Thomas, SH; Thompson, JP; Vale, AJ1
Cain, MR; Mannenbach, MS; Robinson, JA; Schiltz, BM; Schoen, JC1
Kiyota, K1
Das, A; Maiti, A1
Hassanian-Moghaddam, H; Zamani, N1
Bucaloiu, ID; Jha, KK; Sugunaraj, JP; Thakur, LK1
Beauchamp, GA; Kim, J; Valento, M1
Kettritz, R; Luft, FC; Ritter, T; Rudolph, B1
Kowalówka-Zawieja, J; Przystanowicz, J; Sommerfeld-Klatta, K; Zielińska-Psuja, B1
Davis, WT; Koyfman, A; Long, BJ; Ng, PCY; Sessions, DJ1
Jimenez, CA; Mckelvy, BJ; Sagar, AS1
Becker, JU; Böll, B; Burst, V; Carvalho-Fiel, D; Kochanek, M; Prinz, J; Shimabukuro-Vornhagen, A; von Bergwelt-Baildon, M1
Lechner, MG; Lee, JT; Vaidya, A; Weinmann, M1
Cervantes, CE; Chu, A; Heller, D; Lemont, M1
Marino, RT; Pizon, AF; Sidlak, AM; Van Meerbeke, JP1
Hansson, T; Helander, A; Nordmark Grass, J; Villen, T1
Poirier-Blanchette, L; Schwartz, BC; Simard, C1
Leonard, JB; Minhaj, FS1
Brent, J; McMartin, K1
Banerji, S; Hadianfar, A; Hoyte, C; Mehrpour, O; Nakhaee, S; Schimmel, J1
Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C1
Beaulieu, J; Ghannoum, M; Gosselin, S; Hoffman, RS; Hovda, KE; Lavergne, V; Lung, D; Megarbane, B; Roberts, DM; Thanacoody, R1
Clark, RF; Corbett, B; Lasoff, DR; Seltzer, JA1
Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC1
Bird, S; Ghannoum, M; Gosselin, S; Hassanian-Moghaddam, H; Hoffman, RS; Kallab, S; Lavergne, V; Mégarbane, B; Rif, M; Roberts, DM; Wood, DM1

Reviews

24 review(s) available for fomepizole and ethylene glycol

ArticleYear
Novel therapies for ethylene glycol intoxication.
    Current opinion in pediatrics, 1999, Volume: 11, Issue:3

    Topics: Antidotes; Child; Decontamination; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles; Renal Dialysis

1999
Diagnosis and treatment of an unusual cause of metabolic acidosis: ethylene glycol poisoning.
    Acta clinica Belgica, 1999, Volume: 54, Issue:6

    Topics: Acid-Base Imbalance; Acidosis; Alcohol Dehydrogenase; Antidotes; Bone Marrow Diseases; Enzyme Inhibitors; Ethanol; Ethylene Glycol; Female; Follow-Up Studies; Fomepizole; Humans; Middle Aged; Osmolar Concentration; Pyrazoles; Renal Insufficiency; Respiratory Distress Syndrome; Suicide, Attempted

1999
Current management of ethylene glycol poisoning.
    Drugs, 2001, Volume: 61, Issue:7

    Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Half-Life; Humans; Intestinal Absorption; Poisoning; Pyrazoles

2001
Role of fomepizole in the management of ethylene glycol toxicity.
    Pharmacotherapy, 2002, Volume: 22, Issue:3

    Topics: Alcohol Dehydrogenase; Antidotes; Clinical Trials as Topic; Ethanol; Ethylene Glycol; Fomepizole; Humans; MEDLINE; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome

2002
Fomepizole as an antidote for ethylene glycol poisoning.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:6

    Topics: Acid-Base Imbalance; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Kidney; Poisoning; Pyrazoles; Renal Dialysis

2002
Treatment of ethylene glycol poisoning.
    American family physician, 2002, Sep-01, Volume: 66, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar Concentration; Poisoning; Pyrazoles; Renal Dialysis

2002
Current recommendations for treatment of severe toxic alcohol poisonings.
    Intensive care medicine, 2005, Volume: 31, Issue:2

    Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis

2005
Update on antidotes for pediatric poisoning.
    Pediatric emergency care, 2006, Volume: 22, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Antidotes; Antivenins; Child; Child, Preschool; Cholinergic Antagonists; Cholinesterase Inhibitors; Crotalid Venoms; Emergencies; Ethylene Glycol; Female; Fomepizole; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Infant; Infusions, Intravenous; Injections, Intramuscular; Male; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Snake Bites; Syringes

2006
Ethylene glycol poisoning: current diagnostic and management issues.
    Journal of emergency nursing, 2007, Volume: 33, Issue:4

    Topics: Antidotes; Emergencies; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles

2007
Fomepizole: a critical assessment of current dosing recommendations.
    Journal of clinical pharmacology, 2009, Volume: 49, Issue:2

    Topics: Adult; Alcohol Dehydrogenase; Animals; Antidotes; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles

2009
[Non-approved antidotes in Japan].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2008, Volume: 21, Issue:4

    Topics: Antidotes; Calcium Gluconate; Drug Approval; Ethanol; Ethylene Glycol; Ferrocyanides; Fomepizole; Gels; Humans; Hydrofluoric Acid; Injections; Japan; Physostigmine; Pyrazoles; Thallium

2008
Fomepizole for ethylene glycol and methanol poisoning.
    The New England journal of medicine, 2009, May-21, Volume: 360, Issue:21

    Topics: Acidosis; Adult; Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Methanol; Osmolar Concentration; Poisoning; Practice Guidelines as Topic; Pyrazoles; Suicide, Attempted

2009
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:5

    Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene Glycol; Ethylene Glycols; Ethylenes; Fomepizole; Glycols; Humans; Male; Methanol; Pediatrics; Pyrazoles; Renal Dialysis

2010
[Surrogate alcohol poisonings].
    Duodecim; laaketieteellinen aikakauskirja, 2012, Volume: 128, Issue:20

    Topics: Acidosis; Antidotes; Ethylene Glycol; Finland; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis

2012
Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?
    The Netherlands journal of medicine, 2014, Volume: 72, Issue:2

    Topics: Animals; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Solvents

2014
Diagnosis of toxic alcohols: limitations of present methods.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:7

    Topics: Acid-Base Equilibrium; Acidosis; Alcohols; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Osmolar Concentration; Propylene Glycol; Pyrazoles

2015
Antidotes for poisoning by alcohols that form toxic metabolites.
    British journal of clinical pharmacology, 2016, Volume: 81, Issue:3

    Topics: Acidosis; Antidotes; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles

2016
[Antidote update].
    Nihon rinsho. Japanese journal of clinical medicine, 2016, Volume: 74, Issue:2

    Topics: Alcohol Dehydrogenase; Antidotes; Ethylene Glycol; Fomepizole; Humans; Japan; Methanol; Methemoglobinemia; Methylene Blue; Pyrazoles

2016
A Brief Review on Toxic Alcohols: Management Strategies.
    Iranian journal of kidney diseases, 2016, Volume: 10, Issue:6

    Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Solvents

2016
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
    Emergency medicine practice, 2016, Sep-22, Volume: 18, Issue:9 Suppl Po

    Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Propylene Glycol; Pyrazoles; Renal Dialysis

2016
Toxic alcohol diagnosis and management: an emergency medicine review.
    Internal and emergency medicine, 2018, Volume: 13, Issue:3

    Topics: 2-Propanol; Alcohol Drinking; Alcohols; Antidotes; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis

2018
The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:20

    Topics: Acidosis; Antidotes; Delayed Diagnosis; Ethylene Glycol; Female; Fomepizole; Humans; Hyperoxaluria; Middle Aged; Poisoning; Renal Dialysis

2021
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:7

    Topics: Acidosis; Acute Kidney Injury; Alcohol Dehydrogenase; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Renal Dialysis; Retrospective Studies

2022
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup.
    Critical care (London, England), 2023, 02-10, Volume: 27, Issue:1

    Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Glycolates; Humans; Poisoning; Renal Dialysis

2023

Trials

9 trial(s) available for fomepizole and ethylene glycol

ArticleYear
4-Methylpyrazole: a controlled study of safety in healthy human subjects after single, ascending doses.
    Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:4

    Topics: Adult; Alcohol Dehydrogenase; Dizziness; Double-Blind Method; Drug Evaluation; Drug Tolerance; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Nausea; Pyrazoles; Safety

1988
Efficacy of 4-methylpyrazole for treatment of ethylene glycol intoxication in dogs.
    American journal of veterinary research, 1994, Volume: 55, Issue:12

    Topics: Animals; Dog Diseases; Dogs; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Pyrazoles; Time Factors

1994
Comparison of ethanol and 4-methylpyrazole as treatments for ethylene glycol intoxication in cats.
    American journal of veterinary research, 1994, Volume: 55, Issue:12

    Topics: Animals; Cat Diseases; Cats; Ethanol; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Pyrazoles; Time Factors

1994
Kinetic interactions between 4-methylpyrazole and ethanol in healthy humans.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:5

    Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Metabolic Clearance Rate; Methanol; Pyrazoles

1996
Glycolate kinetics and hemodialysis clearance in ethylene glycol poisoning. META Study Group.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:7

    Topics: Adult; Aged; Antidotes; Chromatography, Gas; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-Life; Humans; Male; Middle Aged; Poisoning; Prospective Studies; Pyrazoles; Renal Dialysis

1998
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.
    The New England journal of medicine, 1999, Mar-18, Volume: 340, Issue:11

    Topics: Adult; Aged; Antidotes; Ethylene Glycol; Female; Fomepizole; Glycolates; Humans; Keratolytic Agents; Kidney Diseases; Male; Middle Aged; Oxalates; Poisoning; Prospective Studies; Pyrazoles; Treatment Outcome

1999
Toxicokinetics of ethylene glycol during fomepizole therapy: implications for management. For the Methylpyrazole for Toxic Alcohols Study Group.
    Annals of emergency medicine, 2000, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcoholic Intoxication; Antidotes; Creatine; Dose-Response Relationship, Drug; Emergency Service, Hospital; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Intravenous; Kidney Function Tests; Male; Middle Aged; Probability; Pyrazoles; Renal Dialysis; Treatment Outcome

2000
Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning.
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:3

    Topics: Administration, Oral; Adult; Antidotes; Chromatography, Gas; Dose-Response Relationship, Drug; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Infant; Injections, Intravenous; Liver; Male; Metabolic Clearance Rate; Methanol; Poisoning; Pyrazoles; Tissue Distribution

2004
Analysis of Fomepizole Elimination in Methanol- and Ethylene Glycol-Poisoned Patients.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2022, Volume: 18, Issue:1

    Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisons; Pyrazoles

2022

Other Studies

81 other study(ies) available for fomepizole and ethylene glycol

ArticleYear
4-Methylpyrazole as treatment for naturally acquired ethylene glycol intoxication in dogs.
    Journal of the American Veterinary Medical Association, 1989, Jul-01, Volume: 195, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Ethylene Glycol; Ethylene Glycols; Fomepizole; Pyrazoles

1989
The treatment of ethylene glycol poisoning simplified.
    The New England journal of medicine, 1988, Jul-14, Volume: 319, Issue:2

    Topics: Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Pyrazoles

1988
Treatment of ethylene glycol poisoning with intravenous 4-methylpyrazole.
    The New England journal of medicine, 1988, Jul-14, Volume: 319, Issue:2

    Topics: Adult; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Injections, Intravenous; Male; Pyrazoles; Renal Dialysis; Suicide, Attempted

1988
Comparison of the effects of ethanol and 4-methylpyrazole on the pharmacokinetics and toxicity of ethylene glycol in the dog.
    Toxicology letters, 1987, Volume: 35, Issue:2-3

    Topics: Animals; Bicarbonates; Blood Urea Nitrogen; Dogs; Ethanol; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Kinetics; Male; Pyrazoles; Urodynamics

1987
Efficacy of 4-methylpyrazole in ethylene glycol poisoning: clinical and toxicokinetic aspects.
    Human & experimental toxicology, 1994, Volume: 13, Issue:1

    Topics: Adult; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Poisoning; Pyrazoles

1994
4-Methylpyrazole and hemodialysis in ethylene glycol poisoning.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:4

    Topics: Adult; Antidotes; Ethylene Glycol; Ethylene Glycols; Fomepizole; Half-Life; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis

1996
4-Methylpyrazole--present status.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:4

    Topics: Animals; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis

1996
Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995).
    Journal of the American Veterinary Medical Association, 1996, Dec-01, Volume: 209, Issue:11

    Topics: Acid-Base Equilibrium; Alcohol Dehydrogenase; Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Poisoning; Prognosis; Pyrazoles; Retrospective Studies; Uremia

1996
High-performance liquid chromatographic determination of 4-methylpyrazole in plasma and in dialysate.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Aug-01, Volume: 695, Issue:2

    Topics: Alcohol Dehydrogenase; Chromatography, High Pressure Liquid; Dialysis Solutions; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Poisoning; Pyrazoles; Renal Dialysis; Spectrophotometry, Ultraviolet

1997
Ethylene glycol antidote cleared for marketing.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Jan-15, Volume: 55, Issue:2

    Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Inactivation, Metabolic; Poisoning; Pyrazoles

1998
Toxicology reviews: fomepizole--a new antidote.
    Pediatric emergency care, 1998, Volume: 14, Issue:2

    Topics: Antidotes; Child; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles

1998
Ethylene glycol poisoning treated by intravenous 4-methylpyrazole.
    Intensive care medicine, 1998, Volume: 24, Issue:7

    Topics: Acid-Base Equilibrium; Adult; Antidotes; Biotransformation; Creatinine; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Poisoning; Pyrazoles; Time Factors

1998
Ethylene glycol poisoning in a child treated with 4-methylpyrazole.
    Pediatrics, 1998, Volume: 102, Issue:3

    Topics: Antidotes; Child, Preschool; Chromatography, High Pressure Liquid; Drug Administration Schedule; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Injections, Intravenous; Poisoning; Pyrazoles

1998
In vitro studies of human alcohol dehydrogenase inhibition in the process of methanol and ethylene glycol oxidation.
    Archives of toxicology, 1998, Volume: 72, Issue:9

    Topics: Alcohol Dehydrogenase; Cimetidine; Enzyme Inhibitors; Ethylene Glycol; Fomepizole; Humans; In Vitro Techniques; Liver; Methanol; Methylene Blue; Pyrazoles; Theophylline

1998
A new antidote in review: fomepizole (Antizol).
    Journal of emergency nursing, 1998, Volume: 24, Issue:4

    Topics: Antidotes; Emergency Nursing; Ethylene Glycol; Fomepizole; Humans; Male; Middle Aged; Pyrazoles

1998
New treatment for ethylene glycol poisoning.
    The New England journal of medicine, 1999, Mar-18, Volume: 340, Issue:11

    Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles

1999
Fomepizole in treatment of uncomplicated ethylene glycol poisoning.
    Lancet (London, England), 1999, Sep-04, Volume: 354, Issue:9181

    Topics: Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Male; Pyrazoles; Renal Dialysis

1999
American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.
    Journal of toxicology. Clinical toxicology, 1999, Volume: 37, Issue:5

    Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles

1999
Fomepizole for ethylene-glycol poisoning.
    Lancet (London, England), 1999, Nov-06, Volume: 354, Issue:9190

    Topics: Acute Kidney Injury; Antidotes; Ethylene Glycol; Fomepizole; Health Services Accessibility; Humans; Pyrazoles; Renal Dialysis

1999
Ethylene glycol toxicity: closing in on rational, evidence-based treatment.
    Annals of emergency medicine, 2000, Volume: 36, Issue:2

    Topics: Alcoholic Intoxication; Antidotes; Ethylene Glycol; Evidence-Based Medicine; Fomepizole; Humans; Pyrazoles

2000
Toxicity of ethylene glycol metabolites in normal human kidney cells.
    Annals of the New York Academy of Sciences, 2000, Volume: 919

    Topics: Animals; Cell Death; Cell Line, Transformed; Cells, Cultured; Ethidium; Ethylene Glycol; Fluorescence; Fomepizole; Glycolates; Humans; Kidney; Kidney Tubules; Oxalic Acid; Pyrazoles

2000
Fomepizole treatment of ethylene glycol poisoning in an infant.
    Pediatrics, 2000, Volume: 106, Issue:6

    Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Infant; Male; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome

2000
Fomepizole in the treatment of poisoning.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Adult; Alcohol Dehydrogenase; Antidotes; Child; Drug Costs; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles

2001
Severe ethylene glycol ingestion treated without hemodialysis.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Adolescent; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Poisoning; Pyrazoles; Renal Dialysis

2001
Nystagmus secondary to fomepizole administration in a pediatric patient.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:7

    Topics: Antidotes; Child; Ethylene Glycol; Female; Fomepizole; Humans; Nystagmus, Pathologic; Pyrazoles

2000
Fomepizole in ethylene glycol intoxication.
    Annals of emergency medicine, 2001, Volume: 37, Issue:3

    Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Pyrazoles; Renal Dialysis; Suicide, Attempted; Treatment Outcome

2001
[Ethylene glycol and methanol poisoning. Fomepizole--an alternative antidote].
    Lakartidningen, 2001, Jul-25, Volume: 98, Issue:30-31

    Topics: Adult; Antidotes; Child; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles

2001
[Severe ethylene glycol poisoning treated wtih fomepizole (4-methylpyrazole)].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2002, Oct-20, Volume: 122, Issue:25

    Topics: Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Male; Middle Aged; Poisoning; Pyrazoles

2002
Agitation by sedation.
    Lancet (London, England), 2003, Jan-25, Volume: 361, Issue:9354

    Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypnotics and Sedatives; Lorazepam; Middle Aged; Propylene Glycol; Psychomotor Agitation; Pyrazoles

2003
Ethylene glycol intoxication: case report and pharmacokinetic perspectives.
    Pharmacotherapy, 2003, Volume: 23, Issue:12

    Topics: Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles

2003
Fomepizole alone for severe infant ethylene glycol poisoning.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2004, Volume: 5, Issue:5

    Topics: Accidents, Home; Antidotes; Dose-Response Relationship, Drug; Drug Administration Schedule; Emergency Treatment; Ethylene Glycol; Follow-Up Studies; Fomepizole; Humans; Infant; Intensive Care Units, Pediatric; Male; Poisoning; Pyrazoles; Risk Assessment; Severity of Illness Index; Treatment Outcome

2004
Treatment of severe pediatric ethylene glycol intoxication without hemodialysis.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:3

    Topics: Acidosis; Adolescent; Antidotes; Bicarbonates; Child; Creatine; Disease Progression; Ethylene Glycol; Fomepizole; Humans; Hypoglycemia; Infant; Length of Stay; Pyrazoles; Renal Dialysis; Retrospective Studies; Treatment Outcome

2004
Ethylene glycol toxicity.
    Military medicine, 2004, Volume: 169, Issue:8

    Topics: Acidosis; Acute Kidney Injury; Adolescent; Critical Care; Emergency Treatment; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Suicide, Attempted

2004
Hyperosmolality: another indication for hemodialysis following acute ethylene glycol poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:2

    Topics: Acid-Base Imbalance; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Osmolar Concentration; Poisoning; Pyrazoles; Renal Dialysis

2006
Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote.
    Resuscitation, 2006, Volume: 70, Issue:2

    Topics: Adult; Antidotes; Early Diagnosis; Emergency Medical Services; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles; Suicide, Attempted; Time Factors

2006
Change in mental status.
    The Journal of emergency medicine, 2007, Volume: 32, Issue:2

    Topics: Acidosis; Adult; Antidotes; Confusion; Depression; Drug Overdose; Ethylene Glycol; Fomepizole; Humans; Male; Pyrazoles; Suicide, Attempted

2007
The management of severe toxic alcohol ingestions at a tertiary care center after the introduction of fomepizole.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:7

    Topics: Adult; Alcohol Dehydrogenase; Antidotes; Databases, Factual; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Retrospective Studies; Solvents

2007
Ethylene glycol ingestion treated only with fomepizole.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:3

    Topics: Acid-Base Imbalance; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Injections, Intravenous; Kidney Diseases; Male; Poisoning; Pyrazoles; Suicide, Attempted; Treatment Outcome

2007
Bradycardia and hypotension associated with fomepizole infusion during hemodialysis.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:6

    Topics: Acidosis; Antidotes; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Ethylene Glycol; Fomepizole; Heart Rate; Humans; Hypotension; Infusions, Intravenous; Male; Middle Aged; Pyrazoles; Renal Dialysis

2008
Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole.
    Annals of emergency medicine, 2009, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Cohort Studies; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Proportional Hazards Models; Pyrazoles

2009
Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:10

    Topics: Administration, Oral; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Intravenous; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Retrospective Studies

2008
Ethanol: tastes great! Fomepizole: less filling!
    Annals of emergency medicine, 2009, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Pyrazoles

2009
Discontinuation of 5% alcohol in 5% dextrose injection: implications for antidote stocking.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Dec-01, Volume: 65, Issue:23

    Topics: Alcohols; Antidotes; Drug Therapy, Combination; Ethylene Glycol; Fomepizole; Glucose; Humans; Illinois; Injections, Intravenous; Methanol; Pharmacy Service, Hospital; Poison Control Centers; Poisoning; Practice Guidelines as Topic; Pyrazoles

2008
Re: ethylene glycol ingestion treated only with fomepizole (Journal of Medical Toxicology: volume 3, number 3, September 2007; 125-128).
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:1

    Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Pyrazoles

2008
Fomepizole for toxic alcohol poisoning.
    The New England journal of medicine, 2009, Sep-17, Volume: 361, Issue:12

    Topics: Antidotes; Drug Interactions; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles

2009
[Application in veterinary and human clinical toxicology].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2009, Volume: 22, Issue:4

    Topics: Acetaminophen; Aflatoxins; Animals; Biphenyl Compounds; Cat Diseases; Cats; Chickens; Ethylene Glycol; Fomepizole; Food Contamination; Fumonisins; Humans; Ivermectin; Mercury Poisoning, Nervous System; Plant Oils; Poisoning; Poultry Diseases; Pyrazoles; Rice Bran Oil; Species Specificity; Toxicology; Veterinary Medicine

2009
Massive ethylene glycol ingestion treated with fomepizole alone-a viable therapeutic option.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:2

    Topics: Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Pyrazoles; Suicide, Attempted

2010
Safety and efficacy of high-dose fomepizole compared with ethanol as therapy for ethylene glycol intoxication in cats.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2010, Apr-01, Volume: 20, Issue:2

    Topics: Analysis of Variance; Animals; Antidotes; Cat Diseases; Cats; Central Nervous System Depressants; Ethanol; Ethylene Glycol; Female; Fomepizole; Male; Prospective Studies; Pyrazoles; Treatment Outcome

2010
Calcium oxalate monohydrate crystals: a clue to ethylene glycol poisoning.
    The American journal of the medical sciences, 2011, Volume: 341, Issue:4

    Topics: Antidotes; Calcium Oxalate; Crystallization; Ethylene Glycol; Fomepizole; Humans; Male; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome

2011
Antidotes for alcohol and glycol toxicity: translating mechanisms into treatments.
    Clinical pharmacology and therapeutics, 2010, Volume: 88, Issue:3

    Topics: Animals; Antidotes; Clinical Trials as Topic; Drug Design; Drug Evaluation, Preclinical; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Translational Research, Biomedical

2010
Oxidation of methanol, ethylene glycol, and isopropanol with human alcohol dehydrogenases and the inhibition by ethanol and 4-methylpyrazole.
    Chemico-biological interactions, 2011, May-30, Volume: 191, Issue:1-3

    Topics: 2-Propanol; Alcohol Dehydrogenase; Enzyme Inhibitors; Ethanol; Ethylene Glycol; Fomepizole; Humans; Kinetics; Methanol; Oxidation-Reduction; Pyrazoles

2011
4-Methylpyrazole as a treatment in naturally occurring ethylene glycol intoxication in cats.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2011, Volume: 21, Issue:3

    Topics: Animals; Antidotes; Cat Diseases; Cats; Ethylene Glycol; Female; Fomepizole; Male; Pyrazoles; Treatment Outcome

2011
Medication errors associated with the use of ethanol and fomepizole as antidotes for methanol and ethylene glycol poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:5

    Topics: Adult; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Medication Errors; Methanol; Middle Aged; Pyrazoles

2011
Studies on ethylene glycol poisoning: one patient - 154 admissions.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:6

    Topics: Adult; Antidotes; Dissociative Disorders; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-Life; Humans; Hyperkalemia; Kidney; Liver; Oxalates; Poisoning; Pyrazoles; Recurrence; Renal Dialysis; Suicide

2011
Ethylene glycol elimination kinetics and outcomes in patients managed without hemodialysis.
    Annals of emergency medicine, 2012, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Male; Middle Aged; Pyrazoles; Retrospective Studies; Young Adult

2012
Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old.
    BMJ case reports, 2012, Mar-27, Volume: 2012

    Topics: Antidotes; Child, Preschool; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles

2012
Successful outcome of accidental ethylene glycol poisoning despite delayed presentation.
    BMJ case reports, 2010, Jul-21, Volume: 2010

    Topics: Accidents, Home; Aged; Antidotes; Combined Modality Therapy; Critical Care; Critical Illness; Delayed Diagnosis; Ethylene Glycol; Follow-Up Studies; Fomepizole; Glasgow Coma Scale; Hemofiltration; Humans; Intensive Care Units; Male; Pyrazoles; Risk Assessment; Treatment Outcome

2010
Cost of hemodialysis versus fomepizole-only for treatment of ethylene glycol intoxication.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:3

    Topics: Drug Costs; Ethylene Glycol; Female; Fomepizole; Hospital Costs; Humans; Pyrazoles; Renal Dialysis

2013
Effect of 4-methylpyrazole on antioxidant enzyme status and lipid peroxidation in the liver of rats after exposure to ethylene glycol and ethyl alcohol.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:6

    Topics: Administration, Oral; Animals; Antioxidants; Enzymes; Ethanol; Ethylene Glycol; Fomepizole; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Time Factors

2012
Detectable serum ethylene glycol levels after subcutaneous injection of antifreeze.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:9

    Topics: Abdomen; Adult; Antidotes; Emergency Service, Hospital; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Subcutaneous; Internet; Pyrazoles; Solvents; Suicide, Attempted; Thiamine; Treatment Outcome; Vitamin B Complex; Young Adult

2013
Massive ethylene glycol poisoning triggers osmotic demyelination syndrome.
    The Journal of emergency medicine, 2014, Volume: 46, Issue:3

    Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Myelinolysis, Central Pontine; Osmotic Pressure; Poisoning; Pyrazoles; Renal Dialysis; Water-Electrolyte Balance

2014
Predictors of Death and Prolonged Renal Insufficiency in Ethylene Glycol Poisoning.
    Journal of intensive care medicine, 2015, Volume: 30, Issue:5

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; California; Cause of Death; Creatinine; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Retrospective Studies; Survival Analysis; Time-to-Treatment; Young Adult

2015
[Toxicological analysis is mandatory to interpret elevation in blood lactate concentration in toxic alcohol poisoning].
    Annales francaises d'anesthesie et de reanimation, 2014, Volume: 33, Issue:5

    Topics: Acidosis, Lactic; Antidotes; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Pyrazoles

2014
A rare case of fatal stroke after ethylene glycol toxicity.
    BMJ case reports, 2015, Mar-25, Volume: 2015

    Topics: Antidotes; Ethylene Glycol; Fatal Outcome; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Stroke; Suicide, Attempted

2015
Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS).
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:2

    Topics: Adult; Antidotes; Disease Management; Ethanol; Ethylene Glycol; Fomepizole; Hospitalization; Humans; Methanol; Middle Aged; Poisoning; Prognosis; Prospective Studies; Pyrazoles; United Kingdom; Young Adult

2016
Adolescent Presents With Altered Mental Status and Elevated Anion Gap After Suicide Attempt by Ethylene Glycol Ingestion.
    Pediatric emergency care, 2016, Volume: 32, Issue:10

    Topics: Acidosis; Adolescent; Depressive Disorder, Major; Diagnosis, Differential; Ethylene Glycol; Fomepizole; Humans; Male; Mental Disorders; Pyrazoles; Renal Dialysis; Suicide, Attempted

2016
A man with altered mental status and metabolic acidosis.
    BMJ (Clinical research ed.), 2016, 04-28, Volume: 353

    Topics: Acid-Base Equilibrium; Acidosis; Antidotes; Confusion; Dyspnea; Ethylene Glycol; Fomepizole; Hematuria; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Urinalysis

2016
Sequential episodes of ethylene glycol poisoning in the same person.
    BMJ case reports, 2017, May-27, Volume: 2017

    Topics: Aged; Antidotes; Emergency Service, Hospital; Ethylene Glycol; Fatal Outcome; Fomepizole; Household Products; Humans; Male; Multiple Organ Failure; Pyrazoles; Renal Dialysis; Suicide, Attempted; Time Factors

2017
The Case | Acid-base diagnoses in the 21st century.
    Kidney international, 2017, Volume: 92, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Middle Aged; Pyrazoles

2017
Effect of repeated administration of 4-methylpyrazole on renal function and lipid peroxidation products in rat kidney after ethylene glycol poisoning.
    Environmental toxicology and pharmacology, 2017, Volume: 56

    Topics: Animals; Antidotes; Biotransformation; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylene Glycol; Fomepizole; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Pyrazoles; Rats; Rats, Wistar

2017
Lactate gap as a tool in identifying ethylene glycol poisoning.
    BMJ case reports, 2018, Mar-09, Volume: 2018

    Topics: Acidosis; Antidotes; Diagnosis, Differential; Dialysis; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Middle Aged; Pyrazoles; Treatment Outcome

2018
[Antifreeze poisoning : The case of a patient with repeated ethylene glycol poisoning].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019, Volume: 114, Issue:2

    Topics: Adult; Antidotes; Blood Chemical Analysis; Ethanol; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Renal Dialysis; Suicide, Attempted

2019
Bridging the Gap.
    The New England journal of medicine, 2019, Jan-31, Volume: 380, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar Concentration; Poisoning; Renal Dialysis; Sodium Bicarbonate

2019
Early dialysis in a rare case of combined toxic alcohols ingestion.
    CEN case reports, 2020, Volume: 9, Issue:1

    Topics: Acidosis; Adult; Alcohols; Antidotes; Bicarbonates; Buffers; Combined Modality Therapy; Eating; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Renal Dialysis; Solvents; Treatment Outcome

2020
Single versus continued dosing of fomepizole during hemodialysis in ethylene glycol toxicity.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:2

    Topics: Adult; Aged; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Renal Dialysis

2021
[Simplified laboratory analysis of ethylene glycol allows improved management of poisoning cases].
    Lakartidningen, 2020, 05-25, Volume: 117

    Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles

2020
Spurious point-of-care lactate elevation in ethylene glycol intoxication: rediscovering a clinical pearl.
    BMJ case reports, 2021, Feb-10, Volume: 14, Issue:2

    Topics: Acidosis, Lactic; Aged; Antidotes; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Renal Replacement Therapy; Treatment Outcome

2021
Evaluation of level of care for toxic alcohol ingestions receiving fomepizole.
    The American journal of emergency medicine, 2021, Volume: 50

    Topics: Adult; Aged; Antidotes; Baltimore; Combined Modality Therapy; Critical Care; Ethylene Glycol; Facilities and Services Utilization; Female; Fomepizole; Humans; Intensive Care Units; Male; Methanol; Middle Aged; Retrospective Studies

2021
Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Age Factors; Alcoholic Intoxication; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Incidence; Male; Middle Aged; Mortality; Poison Control Centers; Regression Analysis; Retrospective Studies; United States; Young Adult

2021
Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy.
    The Journal of emergency medicine, 2022, Volume: 63, Issue:1

    Topics: Acidosis; Adult; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Antidotes; Eating; Ethylene Glycol; Ethylene Glycols; Fomepizole; Glycerol; Humans; Male; Octanes; Poisoning; Propylene Glycols; Pyrazoles; Solvents

2022
Mass Poisoning From Ethylene Glycol at a U.S. Military Base.
    Military medicine, 2023, 08-29, Volume: 188, Issue:9-10

    Topics: Acidosis; Ethylene Glycol; Fomepizole; Humans; Military Facilities; Poisoning; Renal Dialysis

2023