fomepizole has been researched along with ethylene glycol in 114 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (4.39) | 18.7374 |
1990's | 22 (19.30) | 18.2507 |
2000's | 39 (34.21) | 29.6817 |
2010's | 36 (31.58) | 24.3611 |
2020's | 12 (10.53) | 2.80 |
Authors | Studies |
---|---|
Dial, SM; Hamar, DW; Thrall, MA | 3 |
Blomstrand, R; Jacobsen, D; McMartin, KE; Sebastian, CS | 1 |
Porter, GA | 1 |
Astier, A; Baud, FJ; Bien, DV; Bismuth, C; Galliot, M; Garnier, R; Likforman, J | 1 |
Grauer, GF; Henre, BA; Hjelle, JJ; Thrall, MA | 1 |
Allain, P; Alquier, P; Bouachour, G; Harry, P; Houze, P; Turcant, A | 1 |
Allain, P; Harry, P; Jobard, E; Roy, PM; Turcant, A | 1 |
Jacobsen, D; McMartin, K | 1 |
Barron, SK; Breau, RL; Dies, DF; Jacobsen, D; McMartin, KE; Sebastian, CS; Spann, EG | 1 |
Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA | 1 |
Allain, P; Harry, P; Jobard, E; Le Bouil, A; Turcant, A | 1 |
Shannon, M | 1 |
Hantson, P; Hassoun, A; Mahieu, P | 1 |
Briand, M; Caubet, A; Harry, P; Jobard, E; Turcant, A | 1 |
Dawidek-Pietryka, K; Dudka, J; Mazur, M; Szczepaniak, S | 1 |
Weinman, SA | 1 |
Brent, J; Ford, MD; Kerns, W; McMartin, KE; Moreau, CL; Rose, SR; Tomaszewski, CA | 1 |
Brent, J; Burkhart, KK; Donovan, JW; Kulig, K; McMartin, K; Phillips, S; Wells, M | 1 |
Jacobsen, D | 1 |
Wiley, JF | 1 |
Baud, FJ; Borron, SW; Mégarbane, B | 2 |
Barceloux, DG; Krenzelok, EP; Olson, K; Watson, W | 1 |
Goldfarb, DS | 1 |
Lejeune, P; Piagnerelli, M; Vanhaeverbeek, M | 1 |
Brent, J; Burns, MJ; McMartin, KE; Sivilotti, ML | 1 |
Watson, WA | 1 |
Cenac, TA; McMartin, KE | 1 |
Aviles, SR; Baum, CR; Goldstein, CA; Langman, CB; Makar, JK; Oker, EE | 1 |
Casavant, MJ | 1 |
Boyer, EW; Mejia, M; Shannon, M; Woolf, A | 1 |
Benitez, JG; Krenzelok, EP; Swanson-Biearman, B | 1 |
Hertko, LJ; Korbet, SM; Leikin, JB; Najafi, CC | 1 |
Brent, J | 3 |
Persson, H | 1 |
Druteika, DP; Ensom, MH; Zed, PJ | 1 |
Battistella, M | 1 |
Archie, TE; Ferguson, DR; Piccaro, JC; Scalley, RD; Smart, ML | 1 |
Aakervik, O; Jacobsen, D; Svendsen, J | 1 |
Nicholson, WJ; Schiffman, F; Tuohy, KA | 1 |
Hellman, RN; Vasavada, N; Williams, C | 1 |
Detaille, T; Di Fazio, V; Hantson, P; Haufroid, V; König, J; Vanbinst, R; Wallemacq, PE | 1 |
Clément de Cléty, S; Dembour, G; Detaille, T; Hantson, P; Vanbinst, R; Wallemacq, P | 1 |
Caravati, EM; Heileson, HL; Jones, M | 1 |
Cox, RD; Phillips, WJ | 1 |
Brooks, DE; Pizon, AF | 1 |
Adnet, F; Amathieu, R; Borron, SW; Lapostolle, F; Merouani, M; Smail, N | 1 |
Liebelt, EL; White, ML | 1 |
Brown, DF; Nadel, ES; Tiamfook-Morgan, TO | 1 |
Gracia, R; Neerman, MF; Velez, LI | 1 |
Green, R | 1 |
Keyes, DC; Lee, YC; Shepherd, G; Velez, LI | 1 |
Brignall, JL; Brubacher, JR; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lam, GS; Lawson, EJ; Lepik, KJ; Purssell, RA | 1 |
Brignall, JL; Daws, DE; DeWitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG | 1 |
Baud, FJ; Houzé, P; Mégarbane, B | 1 |
Sivilotti, ML | 1 |
Bestic, M; Blackford, M; Reed, M | 1 |
Berberet, B; Breier, C; Burda, A; Lodolce, AE | 1 |
Al-Duaij, N; Becker, ML; Ewald, MB; George, M | 1 |
Endo, Y | 1 |
Garza-Ocañas, L; González-Santiago, O | 1 |
Akahori, F | 1 |
Alhelail, M; Brent, J; Buchanan, JA; Cetaruk, EW; Kulig, K; Palmer, RB; Schaeffer, TH | 1 |
Connally, HE; Hamar, DW; Thrall, MA | 1 |
Asif Siddiqui, OM; Luqman, A; Naseer, A; Stanifer, J; Wall, BM | 1 |
McMartin, KE | 1 |
Chi, YC; Lee, SL; Li, YP; Shih, HT; Yin, SJ | 1 |
Powell, LL; Tart, KM | 1 |
Baker, JL; Daws, DE; Dewitt, CR; Erhardt, GD; Kennedy, JR; Lepik, KJ; Levy, AR; Purssell, RA; Sobolev, BG | 1 |
Brørs, O; Hovda, KE; Jacobsen, D; Julsrud, J; Øvrebø, S | 1 |
Bikin, D; Boyer, E; Burns, J; Curry, SC; Gerkin, RD; Levine, M; Pizon, AF; Ruha, AM | 1 |
Duncan, D; Hann, G; Sohi, D; Sudhir, G; West, P | 1 |
Cafferkey, M; Isse, S; Lal, A; Mangera, Z; Winnett, G | 1 |
Ikäheimo, R; Lapatto-Reiniluoto, O | 1 |
Cantrell, FL; Clark, RF; Darracq, MA; Rentmeester, LL; Schneir, AB; Tomaszewski, CA | 1 |
Kowalówka-Zawieja, J; Orłowski, J; Przystanowicz, J; Sommerfeld, K; Zielińska-Psuja, B | 1 |
Dulaney, AR; Murphy, CM; Vitto, MJ | 1 |
Ahmed, A; Engelman, A; Krasowski, MD; Tschetter, PA | 1 |
Brasiel, JA; Kearney, TE; Lung, DD; Olson, KR | 1 |
de Lange, DW; Meulenbelt, J; Rietjens, SJ | 1 |
Mégarbane, B; Résière, D | 1 |
Garg, D; Irani, M; Lim, T | 1 |
Kraut, JA | 1 |
Hovda, KE; Jacobsen, D; McMartin, K | 1 |
Bradberry, SM; Davies, J; Eddleston, M; Gilfillan, C; Jackson, G; Thanacoody, RH; Thomas, SH; Thompson, JP; Vale, AJ | 1 |
Cain, MR; Mannenbach, MS; Robinson, JA; Schiltz, BM; Schoen, JC | 1 |
Kiyota, K | 1 |
Das, A; Maiti, A | 1 |
Hassanian-Moghaddam, H; Zamani, N | 1 |
Bucaloiu, ID; Jha, KK; Sugunaraj, JP; Thakur, LK | 1 |
Beauchamp, GA; Kim, J; Valento, M | 1 |
Kettritz, R; Luft, FC; Ritter, T; Rudolph, B | 1 |
Kowalówka-Zawieja, J; Przystanowicz, J; Sommerfeld-Klatta, K; Zielińska-Psuja, B | 1 |
Davis, WT; Koyfman, A; Long, BJ; Ng, PCY; Sessions, DJ | 1 |
Jimenez, CA; Mckelvy, BJ; Sagar, AS | 1 |
Becker, JU; Böll, B; Burst, V; Carvalho-Fiel, D; Kochanek, M; Prinz, J; Shimabukuro-Vornhagen, A; von Bergwelt-Baildon, M | 1 |
Lechner, MG; Lee, JT; Vaidya, A; Weinmann, M | 1 |
Cervantes, CE; Chu, A; Heller, D; Lemont, M | 1 |
Marino, RT; Pizon, AF; Sidlak, AM; Van Meerbeke, JP | 1 |
Hansson, T; Helander, A; Nordmark Grass, J; Villen, T | 1 |
Poirier-Blanchette, L; Schwartz, BC; Simard, C | 1 |
Leonard, JB; Minhaj, FS | 1 |
Brent, J; McMartin, K | 1 |
Banerji, S; Hadianfar, A; Hoyte, C; Mehrpour, O; Nakhaee, S; Schimmel, J | 1 |
Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C | 1 |
Beaulieu, J; Ghannoum, M; Gosselin, S; Hoffman, RS; Hovda, KE; Lavergne, V; Lung, D; Megarbane, B; Roberts, DM; Thanacoody, R | 1 |
Clark, RF; Corbett, B; Lasoff, DR; Seltzer, JA | 1 |
Banda, M; Forster, BM; Khayat, M; King, JD; Munoz, J; Owshalimpur, D; Petteys, SK; Shah, N; Sullivan, SB; Watson, M; White, WC | 1 |
Bird, S; Ghannoum, M; Gosselin, S; Hassanian-Moghaddam, H; Hoffman, RS; Kallab, S; Lavergne, V; Mégarbane, B; Rif, M; Roberts, DM; Wood, DM | 1 |
24 review(s) available for fomepizole and ethylene glycol
Article | Year |
---|---|
Novel therapies for ethylene glycol intoxication.
Topics: Antidotes; Child; Decontamination; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles; Renal Dialysis | 1999 |
Diagnosis and treatment of an unusual cause of metabolic acidosis: ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Acidosis; Alcohol Dehydrogenase; Antidotes; Bone Marrow Diseases; Enzyme Inhibitors; Ethanol; Ethylene Glycol; Female; Follow-Up Studies; Fomepizole; Humans; Middle Aged; Osmolar Concentration; Pyrazoles; Renal Insufficiency; Respiratory Distress Syndrome; Suicide, Attempted | 1999 |
Current management of ethylene glycol poisoning.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Half-Life; Humans; Intestinal Absorption; Poisoning; Pyrazoles | 2001 |
Role of fomepizole in the management of ethylene glycol toxicity.
Topics: Alcohol Dehydrogenase; Antidotes; Clinical Trials as Topic; Ethanol; Ethylene Glycol; Fomepizole; Humans; MEDLINE; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome | 2002 |
Fomepizole as an antidote for ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Kidney; Poisoning; Pyrazoles; Renal Dialysis | 2002 |
Treatment of ethylene glycol poisoning.
Topics: Acidosis; Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar Concentration; Poisoning; Pyrazoles; Renal Dialysis | 2002 |
Current recommendations for treatment of severe toxic alcohol poisonings.
Topics: Alcohol Dehydrogenase; Alcoholic Intoxication; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 2005 |
Update on antidotes for pediatric poisoning.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Antidotes; Antivenins; Child; Child, Preschool; Cholinergic Antagonists; Cholinesterase Inhibitors; Crotalid Venoms; Emergencies; Ethylene Glycol; Female; Fomepizole; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Infant; Infusions, Intravenous; Injections, Intramuscular; Male; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Snake Bites; Syringes | 2006 |
Ethylene glycol poisoning: current diagnostic and management issues.
Topics: Antidotes; Emergencies; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 2007 |
Fomepizole: a critical assessment of current dosing recommendations.
Topics: Adult; Alcohol Dehydrogenase; Animals; Antidotes; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Induction; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles | 2009 |
[Non-approved antidotes in Japan].
Topics: Antidotes; Calcium Gluconate; Drug Approval; Ethanol; Ethylene Glycol; Ferrocyanides; Fomepizole; Gels; Humans; Hydrofluoric Acid; Injections; Japan; Physostigmine; Pyrazoles; Thallium | 2008 |
Fomepizole for ethylene glycol and methanol poisoning.
Topics: Acidosis; Adult; Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Methanol; Osmolar Concentration; Poisoning; Practice Guidelines as Topic; Pyrazoles; Suicide, Attempted | 2009 |
Fomepizole for the treatment of pediatric ethylene and diethylene glycol, butoxyethanol, and methanol poisonings.
Topics: Acidosis; Adult; Alcoholism; Antidotes; Bicarbonates; Child; Disease Progression; Ethanol; Ethylene Glycol; Ethylene Glycols; Ethylenes; Fomepizole; Glycols; Humans; Male; Methanol; Pediatrics; Pyrazoles; Renal Dialysis | 2010 |
[Surrogate alcohol poisonings].
Topics: Acidosis; Antidotes; Ethylene Glycol; Finland; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis | 2012 |
Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?
Topics: Animals; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Solvents | 2014 |
Diagnosis of toxic alcohols: limitations of present methods.
Topics: Acid-Base Equilibrium; Acidosis; Alcohols; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Osmolar Concentration; Propylene Glycol; Pyrazoles | 2015 |
Antidotes for poisoning by alcohols that form toxic metabolites.
Topics: Acidosis; Antidotes; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles | 2016 |
[Antidote update].
Topics: Alcohol Dehydrogenase; Antidotes; Ethylene Glycol; Fomepizole; Humans; Japan; Methanol; Methemoglobinemia; Methylene Blue; Pyrazoles | 2016 |
A Brief Review on Toxic Alcohols: Management Strategies.
Topics: 2-Propanol; Acidosis; Alcoholism; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Iran; Methanol; Poisoning; Pyrazoles; Renal Dialysis; Sodium Bicarbonate; Solvents | 2016 |
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Propylene Glycol; Pyrazoles; Renal Dialysis | 2016 |
Toxic alcohol diagnosis and management: an emergency medicine review.
Topics: 2-Propanol; Alcohol Drinking; Alcohols; Antidotes; Emergency Service, Hospital; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 2018 |
The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review.
Topics: Acidosis; Antidotes; Delayed Diagnosis; Ethylene Glycol; Female; Fomepizole; Humans; Hyperoxaluria; Middle Aged; Poisoning; Renal Dialysis | 2021 |
Treating ethylene glycol poisoning with alcohol dehydrogenase inhibition, but without extracorporeal treatments: a systematic review.
Topics: Acidosis; Acute Kidney Injury; Alcohol Dehydrogenase; Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Renal Dialysis; Retrospective Studies | 2022 |
Extracorporeal treatment for ethylene glycol poisoning: systematic review and recommendations from the EXTRIP workgroup.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Glycolates; Humans; Poisoning; Renal Dialysis | 2023 |
9 trial(s) available for fomepizole and ethylene glycol
Article | Year |
---|---|
4-Methylpyrazole: a controlled study of safety in healthy human subjects after single, ascending doses.
Topics: Adult; Alcohol Dehydrogenase; Dizziness; Double-Blind Method; Drug Evaluation; Drug Tolerance; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Nausea; Pyrazoles; Safety | 1988 |
Efficacy of 4-methylpyrazole for treatment of ethylene glycol intoxication in dogs.
Topics: Animals; Dog Diseases; Dogs; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Pyrazoles; Time Factors | 1994 |
Comparison of ethanol and 4-methylpyrazole as treatments for ethylene glycol intoxication in cats.
Topics: Animals; Cat Diseases; Cats; Ethanol; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Pyrazoles; Time Factors | 1994 |
Kinetic interactions between 4-methylpyrazole and ethanol in healthy humans.
Topics: Adult; Alcohol Dehydrogenase; Alcohol Drinking; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Ethanol; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Metabolic Clearance Rate; Methanol; Pyrazoles | 1996 |
Glycolate kinetics and hemodialysis clearance in ethylene glycol poisoning. META Study Group.
Topics: Adult; Aged; Antidotes; Chromatography, Gas; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-Life; Humans; Male; Middle Aged; Poisoning; Prospective Studies; Pyrazoles; Renal Dialysis | 1998 |
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.
Topics: Adult; Aged; Antidotes; Ethylene Glycol; Female; Fomepizole; Glycolates; Humans; Keratolytic Agents; Kidney Diseases; Male; Middle Aged; Oxalates; Poisoning; Prospective Studies; Pyrazoles; Treatment Outcome | 1999 |
Toxicokinetics of ethylene glycol during fomepizole therapy: implications for management. For the Methylpyrazole for Toxic Alcohols Study Group.
Topics: Adolescent; Adult; Aged; Alcohol Dehydrogenase; Alcoholic Intoxication; Antidotes; Creatine; Dose-Response Relationship, Drug; Emergency Service, Hospital; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Intravenous; Kidney Function Tests; Male; Middle Aged; Probability; Pyrazoles; Renal Dialysis; Treatment Outcome | 2000 |
Plasma and tissue determination of 4-methylpyrazole for pharmacokinetic analysis in acute adult and pediatric methanol/ethylene glycol poisoning.
Topics: Administration, Oral; Adult; Antidotes; Chromatography, Gas; Dose-Response Relationship, Drug; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Infant; Injections, Intravenous; Liver; Male; Metabolic Clearance Rate; Methanol; Poisoning; Pyrazoles; Tissue Distribution | 2004 |
Analysis of Fomepizole Elimination in Methanol- and Ethylene Glycol-Poisoned Patients.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisons; Pyrazoles | 2022 |
81 other study(ies) available for fomepizole and ethylene glycol
Article | Year |
---|---|
4-Methylpyrazole as treatment for naturally acquired ethylene glycol intoxication in dogs.
Topics: Animals; Dog Diseases; Dogs; Ethylene Glycol; Ethylene Glycols; Fomepizole; Pyrazoles | 1989 |
The treatment of ethylene glycol poisoning simplified.
Topics: Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Pyrazoles | 1988 |
Treatment of ethylene glycol poisoning with intravenous 4-methylpyrazole.
Topics: Adult; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Injections, Intravenous; Male; Pyrazoles; Renal Dialysis; Suicide, Attempted | 1988 |
Comparison of the effects of ethanol and 4-methylpyrazole on the pharmacokinetics and toxicity of ethylene glycol in the dog.
Topics: Animals; Bicarbonates; Blood Urea Nitrogen; Dogs; Ethanol; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Kinetics; Male; Pyrazoles; Urodynamics | 1987 |
Efficacy of 4-methylpyrazole in ethylene glycol poisoning: clinical and toxicokinetic aspects.
Topics: Adult; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 1994 |
4-Methylpyrazole and hemodialysis in ethylene glycol poisoning.
Topics: Adult; Antidotes; Ethylene Glycol; Ethylene Glycols; Fomepizole; Half-Life; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis | 1996 |
4-Methylpyrazole--present status.
Topics: Animals; Antidotes; Clinical Trials as Topic; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Methanol; Pyrazoles; Renal Dialysis | 1996 |
Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995).
Topics: Acid-Base Equilibrium; Alcohol Dehydrogenase; Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Ethylene Glycol; Ethylene Glycols; Female; Fomepizole; Male; Poisoning; Prognosis; Pyrazoles; Retrospective Studies; Uremia | 1996 |
High-performance liquid chromatographic determination of 4-methylpyrazole in plasma and in dialysate.
Topics: Alcohol Dehydrogenase; Chromatography, High Pressure Liquid; Dialysis Solutions; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Poisoning; Pyrazoles; Renal Dialysis; Spectrophotometry, Ultraviolet | 1997 |
Ethylene glycol antidote cleared for marketing.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Inactivation, Metabolic; Poisoning; Pyrazoles | 1998 |
Toxicology reviews: fomepizole--a new antidote.
Topics: Antidotes; Child; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles | 1998 |
Ethylene glycol poisoning treated by intravenous 4-methylpyrazole.
Topics: Acid-Base Equilibrium; Adult; Antidotes; Biotransformation; Creatinine; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Poisoning; Pyrazoles; Time Factors | 1998 |
Ethylene glycol poisoning in a child treated with 4-methylpyrazole.
Topics: Antidotes; Child, Preschool; Chromatography, High Pressure Liquid; Drug Administration Schedule; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Injections, Intravenous; Poisoning; Pyrazoles | 1998 |
In vitro studies of human alcohol dehydrogenase inhibition in the process of methanol and ethylene glycol oxidation.
Topics: Alcohol Dehydrogenase; Cimetidine; Enzyme Inhibitors; Ethylene Glycol; Fomepizole; Humans; In Vitro Techniques; Liver; Methanol; Methylene Blue; Pyrazoles; Theophylline | 1998 |
A new antidote in review: fomepizole (Antizol).
Topics: Antidotes; Emergency Nursing; Ethylene Glycol; Fomepizole; Humans; Male; Middle Aged; Pyrazoles | 1998 |
New treatment for ethylene glycol poisoning.
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 1999 |
Fomepizole in treatment of uncomplicated ethylene glycol poisoning.
Topics: Acute Kidney Injury; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Male; Pyrazoles; Renal Dialysis | 1999 |
American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 1999 |
Fomepizole for ethylene-glycol poisoning.
Topics: Acute Kidney Injury; Antidotes; Ethylene Glycol; Fomepizole; Health Services Accessibility; Humans; Pyrazoles; Renal Dialysis | 1999 |
Ethylene glycol toxicity: closing in on rational, evidence-based treatment.
Topics: Alcoholic Intoxication; Antidotes; Ethylene Glycol; Evidence-Based Medicine; Fomepizole; Humans; Pyrazoles | 2000 |
Toxicity of ethylene glycol metabolites in normal human kidney cells.
Topics: Animals; Cell Death; Cell Line, Transformed; Cells, Cultured; Ethidium; Ethylene Glycol; Fluorescence; Fomepizole; Glycolates; Humans; Kidney; Kidney Tubules; Oxalic Acid; Pyrazoles | 2000 |
Fomepizole treatment of ethylene glycol poisoning in an infant.
Topics: Antidotes; Ethylene Glycol; Fomepizole; Humans; Infant; Male; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome | 2000 |
Fomepizole in the treatment of poisoning.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Child; Drug Costs; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2001 |
Severe ethylene glycol ingestion treated without hemodialysis.
Topics: Adolescent; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Poisoning; Pyrazoles; Renal Dialysis | 2001 |
Nystagmus secondary to fomepizole administration in a pediatric patient.
Topics: Antidotes; Child; Ethylene Glycol; Female; Fomepizole; Humans; Nystagmus, Pathologic; Pyrazoles | 2000 |
Fomepizole in ethylene glycol intoxication.
Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Pyrazoles; Renal Dialysis; Suicide, Attempted; Treatment Outcome | 2001 |
[Ethylene glycol and methanol poisoning. Fomepizole--an alternative antidote].
Topics: Adult; Antidotes; Child; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Practice Guidelines as Topic; Pyrazoles | 2001 |
[Severe ethylene glycol poisoning treated wtih fomepizole (4-methylpyrazole)].
Topics: Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Infusions, Intravenous; Male; Middle Aged; Poisoning; Pyrazoles | 2002 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypnotics and Sedatives; Lorazepam; Middle Aged; Propylene Glycol; Psychomotor Agitation; Pyrazoles | 2003 |
Ethylene glycol intoxication: case report and pharmacokinetic perspectives.
Topics: Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 2003 |
Fomepizole alone for severe infant ethylene glycol poisoning.
Topics: Accidents, Home; Antidotes; Dose-Response Relationship, Drug; Drug Administration Schedule; Emergency Treatment; Ethylene Glycol; Follow-Up Studies; Fomepizole; Humans; Infant; Intensive Care Units, Pediatric; Male; Poisoning; Pyrazoles; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2004 |
Treatment of severe pediatric ethylene glycol intoxication without hemodialysis.
Topics: Acidosis; Adolescent; Antidotes; Bicarbonates; Child; Creatine; Disease Progression; Ethylene Glycol; Fomepizole; Humans; Hypoglycemia; Infant; Length of Stay; Pyrazoles; Renal Dialysis; Retrospective Studies; Treatment Outcome | 2004 |
Ethylene glycol toxicity.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Critical Care; Emergency Treatment; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Suicide, Attempted | 2004 |
Hyperosmolality: another indication for hemodialysis following acute ethylene glycol poisoning.
Topics: Acid-Base Imbalance; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Osmolar Concentration; Poisoning; Pyrazoles; Renal Dialysis | 2006 |
Prehospital diagnosis of massive ethylene glycol poisoning and use of an early antidote.
Topics: Adult; Antidotes; Early Diagnosis; Emergency Medical Services; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles; Suicide, Attempted; Time Factors | 2006 |
Change in mental status.
Topics: Acidosis; Adult; Antidotes; Confusion; Depression; Drug Overdose; Ethylene Glycol; Fomepizole; Humans; Male; Pyrazoles; Suicide, Attempted | 2007 |
The management of severe toxic alcohol ingestions at a tertiary care center after the introduction of fomepizole.
Topics: Adult; Alcohol Dehydrogenase; Antidotes; Databases, Factual; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Retrospective Studies; Solvents | 2007 |
Ethylene glycol ingestion treated only with fomepizole.
Topics: Acid-Base Imbalance; Adult; Antidotes; Ethylene Glycol; Fomepizole; Humans; Injections, Intravenous; Kidney Diseases; Male; Poisoning; Pyrazoles; Suicide, Attempted; Treatment Outcome | 2007 |
Bradycardia and hypotension associated with fomepizole infusion during hemodialysis.
Topics: Acidosis; Antidotes; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Ethylene Glycol; Fomepizole; Heart Rate; Humans; Hypotension; Infusions, Intravenous; Male; Middle Aged; Pyrazoles; Renal Dialysis | 2008 |
Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Cohort Studies; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Proportional Hazards Models; Pyrazoles | 2009 |
Oral fomepizole administration to treat ethylene glycol and methanol poisonings: advantages and limitations.
Topics: Administration, Oral; Adult; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Intravenous; Male; Methanol; Middle Aged; Poisoning; Pyrazoles; Retrospective Studies | 2008 |
Ethanol: tastes great! Fomepizole: less filling!
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Methanol; Middle Aged; Pyrazoles | 2009 |
Discontinuation of 5% alcohol in 5% dextrose injection: implications for antidote stocking.
Topics: Alcohols; Antidotes; Drug Therapy, Combination; Ethylene Glycol; Fomepizole; Glucose; Humans; Illinois; Injections, Intravenous; Methanol; Pharmacy Service, Hospital; Poison Control Centers; Poisoning; Practice Guidelines as Topic; Pyrazoles | 2008 |
Re: ethylene glycol ingestion treated only with fomepizole (Journal of Medical Toxicology: volume 3, number 3, September 2007; 125-128).
Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Pyrazoles | 2008 |
Fomepizole for toxic alcohol poisoning.
Topics: Antidotes; Drug Interactions; Ethanol; Ethylene Glycol; Fomepizole; Humans; Methanol; Poisoning; Pyrazoles | 2009 |
[Application in veterinary and human clinical toxicology].
Topics: Acetaminophen; Aflatoxins; Animals; Biphenyl Compounds; Cat Diseases; Cats; Chickens; Ethylene Glycol; Fomepizole; Food Contamination; Fumonisins; Humans; Ivermectin; Mercury Poisoning, Nervous System; Plant Oils; Poisoning; Poultry Diseases; Pyrazoles; Rice Bran Oil; Species Specificity; Toxicology; Veterinary Medicine | 2009 |
Massive ethylene glycol ingestion treated with fomepizole alone-a viable therapeutic option.
Topics: Antidotes; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Pyrazoles; Suicide, Attempted | 2010 |
Safety and efficacy of high-dose fomepizole compared with ethanol as therapy for ethylene glycol intoxication in cats.
Topics: Analysis of Variance; Animals; Antidotes; Cat Diseases; Cats; Central Nervous System Depressants; Ethanol; Ethylene Glycol; Female; Fomepizole; Male; Prospective Studies; Pyrazoles; Treatment Outcome | 2010 |
Calcium oxalate monohydrate crystals: a clue to ethylene glycol poisoning.
Topics: Antidotes; Calcium Oxalate; Crystallization; Ethylene Glycol; Fomepizole; Humans; Male; Middle Aged; Poisoning; Pyrazoles; Renal Dialysis; Treatment Outcome | 2011 |
Antidotes for alcohol and glycol toxicity: translating mechanisms into treatments.
Topics: Animals; Antidotes; Clinical Trials as Topic; Drug Design; Drug Evaluation, Preclinical; Ethylene Glycol; Fomepizole; Humans; Methanol; Pyrazoles; Translational Research, Biomedical | 2010 |
Oxidation of methanol, ethylene glycol, and isopropanol with human alcohol dehydrogenases and the inhibition by ethanol and 4-methylpyrazole.
Topics: 2-Propanol; Alcohol Dehydrogenase; Enzyme Inhibitors; Ethanol; Ethylene Glycol; Fomepizole; Humans; Kinetics; Methanol; Oxidation-Reduction; Pyrazoles | 2011 |
4-Methylpyrazole as a treatment in naturally occurring ethylene glycol intoxication in cats.
Topics: Animals; Antidotes; Cat Diseases; Cats; Ethylene Glycol; Female; Fomepizole; Male; Pyrazoles; Treatment Outcome | 2011 |
Medication errors associated with the use of ethanol and fomepizole as antidotes for methanol and ethylene glycol poisoning.
Topics: Adult; Antidotes; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Medication Errors; Methanol; Middle Aged; Pyrazoles | 2011 |
Studies on ethylene glycol poisoning: one patient - 154 admissions.
Topics: Adult; Antidotes; Dissociative Disorders; Ethylene Glycol; Female; Fomepizole; Glycolates; Half-Life; Humans; Hyperkalemia; Kidney; Liver; Oxalates; Poisoning; Pyrazoles; Recurrence; Renal Dialysis; Suicide | 2011 |
Ethylene glycol elimination kinetics and outcomes in patients managed without hemodialysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; Ethylene Glycol; Female; Fomepizole; Half-Life; Humans; Male; Middle Aged; Pyrazoles; Retrospective Studies; Young Adult | 2012 |
Antifreeze on a freezing morning: ethylene glycol poisoning in a 2-year-old.
Topics: Antidotes; Child, Preschool; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Pyrazoles | 2012 |
Successful outcome of accidental ethylene glycol poisoning despite delayed presentation.
Topics: Accidents, Home; Aged; Antidotes; Combined Modality Therapy; Critical Care; Critical Illness; Delayed Diagnosis; Ethylene Glycol; Follow-Up Studies; Fomepizole; Glasgow Coma Scale; Hemofiltration; Humans; Intensive Care Units; Male; Pyrazoles; Risk Assessment; Treatment Outcome | 2010 |
Cost of hemodialysis versus fomepizole-only for treatment of ethylene glycol intoxication.
Topics: Drug Costs; Ethylene Glycol; Female; Fomepizole; Hospital Costs; Humans; Pyrazoles; Renal Dialysis | 2013 |
Effect of 4-methylpyrazole on antioxidant enzyme status and lipid peroxidation in the liver of rats after exposure to ethylene glycol and ethyl alcohol.
Topics: Administration, Oral; Animals; Antioxidants; Enzymes; Ethanol; Ethylene Glycol; Fomepizole; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Time Factors | 2012 |
Detectable serum ethylene glycol levels after subcutaneous injection of antifreeze.
Topics: Abdomen; Adult; Antidotes; Emergency Service, Hospital; Ethylene Glycol; Female; Fomepizole; Humans; Injections, Subcutaneous; Internet; Pyrazoles; Solvents; Suicide, Attempted; Thiamine; Treatment Outcome; Vitamin B Complex; Young Adult | 2013 |
Massive ethylene glycol poisoning triggers osmotic demyelination syndrome.
Topics: Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Middle Aged; Myelinolysis, Central Pontine; Osmotic Pressure; Poisoning; Pyrazoles; Renal Dialysis; Water-Electrolyte Balance | 2014 |
Predictors of Death and Prolonged Renal Insufficiency in Ethylene Glycol Poisoning.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antidotes; California; Cause of Death; Creatinine; Ethanol; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Retrospective Studies; Survival Analysis; Time-to-Treatment; Young Adult | 2015 |
[Toxicological analysis is mandatory to interpret elevation in blood lactate concentration in toxic alcohol poisoning].
Topics: Acidosis, Lactic; Antidotes; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Pyrazoles | 2014 |
A rare case of fatal stroke after ethylene glycol toxicity.
Topics: Antidotes; Ethylene Glycol; Fatal Outcome; Fomepizole; Humans; Male; Middle Aged; Pyrazoles; Stroke; Suicide, Attempted | 2015 |
Management of poisoning with ethylene glycol and methanol in the UK: a prospective study conducted by the National Poisons Information Service (NPIS).
Topics: Adult; Antidotes; Disease Management; Ethanol; Ethylene Glycol; Fomepizole; Hospitalization; Humans; Methanol; Middle Aged; Poisoning; Prognosis; Prospective Studies; Pyrazoles; United Kingdom; Young Adult | 2016 |
Adolescent Presents With Altered Mental Status and Elevated Anion Gap After Suicide Attempt by Ethylene Glycol Ingestion.
Topics: Acidosis; Adolescent; Depressive Disorder, Major; Diagnosis, Differential; Ethylene Glycol; Fomepizole; Humans; Male; Mental Disorders; Pyrazoles; Renal Dialysis; Suicide, Attempted | 2016 |
A man with altered mental status and metabolic acidosis.
Topics: Acid-Base Equilibrium; Acidosis; Antidotes; Confusion; Dyspnea; Ethylene Glycol; Fomepizole; Hematuria; Humans; Male; Middle Aged; Pyrazoles; Renal Dialysis; Urinalysis | 2016 |
Sequential episodes of ethylene glycol poisoning in the same person.
Topics: Aged; Antidotes; Emergency Service, Hospital; Ethylene Glycol; Fatal Outcome; Fomepizole; Household Products; Humans; Male; Multiple Organ Failure; Pyrazoles; Renal Dialysis; Suicide, Attempted; Time Factors | 2017 |
The Case | Acid-base diagnoses in the 21st century.
Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Middle Aged; Pyrazoles | 2017 |
Effect of repeated administration of 4-methylpyrazole on renal function and lipid peroxidation products in rat kidney after ethylene glycol poisoning.
Topics: Animals; Antidotes; Biotransformation; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethylene Glycol; Fomepizole; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Pyrazoles; Rats; Rats, Wistar | 2017 |
Lactate gap as a tool in identifying ethylene glycol poisoning.
Topics: Acidosis; Antidotes; Diagnosis, Differential; Dialysis; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Middle Aged; Pyrazoles; Treatment Outcome | 2018 |
[Antifreeze poisoning : The case of a patient with repeated ethylene glycol poisoning].
Topics: Adult; Antidotes; Blood Chemical Analysis; Ethanol; Ethylene Glycol; Fomepizole; Humans; Male; Poisoning; Renal Dialysis; Suicide, Attempted | 2019 |
Bridging the Gap.
Topics: Acid-Base Equilibrium; Adult; Blood Chemical Analysis; Ethylene Glycol; Fomepizole; Humans; Male; Osmolar Concentration; Poisoning; Renal Dialysis; Sodium Bicarbonate | 2019 |
Early dialysis in a rare case of combined toxic alcohols ingestion.
Topics: Acidosis; Adult; Alcohols; Antidotes; Bicarbonates; Buffers; Combined Modality Therapy; Eating; Ethylene Glycol; Ethylene Glycols; Fomepizole; Humans; Male; Methanol; Renal Dialysis; Solvents; Treatment Outcome | 2020 |
Single versus continued dosing of fomepizole during hemodialysis in ethylene glycol toxicity.
Topics: Adult; Aged; Ethylene Glycol; Female; Fomepizole; Humans; Male; Middle Aged; Renal Dialysis | 2021 |
[Simplified laboratory analysis of ethylene glycol allows improved management of poisoning cases].
Topics: Antidotes; Ethanol; Ethylene Glycol; Fomepizole; Humans; Poisoning; Pyrazoles | 2020 |
Spurious point-of-care lactate elevation in ethylene glycol intoxication: rediscovering a clinical pearl.
Topics: Acidosis, Lactic; Aged; Antidotes; Ethylene Glycol; Fomepizole; Humans; Lactic Acid; Male; Renal Replacement Therapy; Treatment Outcome | 2021 |
Evaluation of level of care for toxic alcohol ingestions receiving fomepizole.
Topics: Adult; Aged; Antidotes; Baltimore; Combined Modality Therapy; Critical Care; Ethylene Glycol; Facilities and Services Utilization; Female; Fomepizole; Humans; Intensive Care Units; Male; Methanol; Middle Aged; Retrospective Studies | 2021 |
Toxic alcohol poisoning characteristics and treatments from 2000 to 2017 at a United States regional poison center.
Topics: Adolescent; Adult; Age Factors; Alcoholic Intoxication; Antidotes; Ethylene Glycol; Female; Fomepizole; Humans; Incidence; Male; Middle Aged; Mortality; Poison Control Centers; Regression Analysis; Retrospective Studies; United States; Young Adult | 2021 |
Symptomatic Diethylene Glycol Ingestion Successfully Treated with Fomepizole Monotherapy.
Topics: Acidosis; Adult; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Antidotes; Eating; Ethylene Glycol; Ethylene Glycols; Fomepizole; Glycerol; Humans; Male; Octanes; Poisoning; Propylene Glycols; Pyrazoles; Solvents | 2022 |
Mass Poisoning From Ethylene Glycol at a U.S. Military Base.
Topics: Acidosis; Ethylene Glycol; Fomepizole; Humans; Military Facilities; Poisoning; Renal Dialysis | 2023 |