fomepizole has been researched along with acetylcysteine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 17 (70.83) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Acar, HV; Cankir, Z; Cermik, H; Cinan, U; Danaci, M; Küçükardali, Y; Nalbant, S; Ozkan, S; Top, C | 1 |
| Calello, DP; Henretig, FM; Osterhoudt, KC | 1 |
| Liebelt, EL; White, ML | 1 |
| Fechter, L; Fulton, S; Gearhart, C; Nelson-Miller, A; Pouyatos, B | 1 |
| Chen, YT; Hung, DZ; Liao, JW | 1 |
| Beuhler, MC; Shah, KR | 1 |
| Hays, WB; Patel, KH; Woolum, JA | 1 |
| Beuhler, MC; Dulaney, A; Fox, C; Geib, AJ; Kerns Ii, W; Kopec, K; Murphy, C; Shah, KR | 1 |
| Freeman, WE; Mullins, ME; Yeager, LH | 1 |
| Akakpo, JY; Jaeschke, H; Ramachandran, A | 1 |
| Akakpo, JY; Curry, SC; Jaeschke, H; Jaeschke, MW; Ramachandran, A; Rumack, BH | 1 |
| Link, SL; Osmon, S; Rampon, G; Rumack, BH; Scalzo, AJ | 2 |
| Lebin, JA; Mudan, A | 1 |
| Hoffman, RS; Mahonski, S; Mohan, S | 1 |
| Bateman, DN; Dear, JW; Eddleston, M; Vale, JA | 1 |
| Akakpo, JY; Curry, SC; Jaeschke, H; Ramachandran, A; Rumack, BH | 1 |
| Dart, RC; Kaiser, SK | 1 |
| Berg, SE; Filip, AB; Mullins, ME; Schwarz, ES | 1 |
| Dear, JW | 1 |
| Filip, AB; Mullins, ME | 1 |
| Bateman, DN; Dear, JW | 1 |
7 review(s) available for fomepizole and acetylcysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New and novel antidotes in pediatrics.
Topics: Acetylcysteine; Antidotes; Antivenins; Child; Fomepizole; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Octreotide; Pyrazoles | 2006 |
Update on antidotes for pediatric poisoning.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Adolescent; Antidotes; Antivenins; Child; Child, Preschool; Cholinergic Antagonists; Cholinesterase Inhibitors; Crotalid Venoms; Emergencies; Ethylene Glycol; Female; Fomepizole; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fragments; Infant; Infusions, Intravenous; Injections, Intramuscular; Male; Methanol; Poisoning; Practice Guidelines as Topic; Pyrazoles; Snake Bites; Syringes | 2006 |
Metabolic and mitochondrial treatments for severe paracetamol poisoning: a systematic review.
Topics: Acetaminophen; Acetylcysteine; Acidosis; Animals; Antidotes; Cimetidine; Drug Overdose; Edetic Acid; Fomepizole; Humans; Mitochondria; Pyridoxal Phosphate | 2020 |
Novel strategies for the treatment of acetaminophen hepatotoxicity.
Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate | 2020 |
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Fomepizole; Hepatocytes; Humans; Mice | 2022 |
The Roles of Antidotes in Emergency Situations.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Fomepizole; Humans; Methylene Blue | 2022 |
17 other study(ies) available for fomepizole and acetylcysteine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the therapeutic efficacy of 4-methylpyrazole and N-acetylcysteine on acetaminophen (paracetamol) hepatotoxicity in rats.
Topics: Acetaminophen; Acetylcysteine; Alcohol Dehydrogenase; Analgesics, Non-Narcotic; Animals; Antidotes; Drug Therapy, Combination; Fomepizole; Liver; Male; Necrosis; Pyrazoles; Rats; Rats, Wistar; Transaminases | 2002 |
Oxidative stress pathways in the potentiation of noise-induced hearing loss by acrylonitrile.
Topics: Acetylcysteine; Acrylonitrile; Action Potentials; Animals; Antioxidants; Cochlea; Cyanides; Fomepizole; Glutathione; Hearing Loss, Noise-Induced; Liver; Male; Otoacoustic Emissions, Spontaneous; Oxidative Stress; Pyrazoles; Rats; Rats, Long-Evans; Reactive Oxygen Species; Thiosulfates | 2007 |
Protective effects of fomepizole on 2-chloroethanol toxicity.
Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Antidotes; Antioxidants; Disulfiram; Drug Synergism; Enzyme Inhibitors; Ethylene Chlorohydrin; Fomepizole; Glutathione; Kidney; Lethal Dose 50; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Solvents | 2010 |
Fomepizole as an Adjunctive Treatment in Severe Acetaminophen Toxicity.
Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Drug Overdose; Fomepizole; Humans; Male; Treatment Outcome | 2020 |
Use of fomepizole, n-acetylcysteine, and hemodialysis for massive acetaminophen overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Drug Overdose; Fomepizole; Free Radical Scavengers; Humans; Male; Middle Aged; Renal Dialysis | 2020 |
Fomepizole as an adjunctive treatment in severe acetaminophen ingestions: a case series.
Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Antidotes; Drug Overdose; Drug Therapy, Combination; Female; Fomepizole; Humans; Middle Aged; Treatment Outcome | 2021 |
Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole.
Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Cell Proliferation; Chemical and Drug Induced Liver Injury; Drug Overdose; Fomepizole; Hepatocytes; Humans; Male; Mice; Mice, Inbred C57BL; Time Factors | 2021 |
Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Fomepizole; Humans | 2022 |
Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Fomepizole; Humans | 2022 |
Reply to Comments on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Fomepizole; Humans | 2022 |
Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Fomepizole; Humans | 2022 |
Comment on Fomepizole as an adjunct in acetylcysteine treated acetaminophen overdose patients: a case series.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Fomepizole; Humans | 2022 |
Fomepizole as an adjunctive therapy for acetaminophen poisoning: cases reported to the toxicology investigators consortium (ToxIC) database 2015-2020.
Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Databases, Factual; Fomepizole; Humans | 2022 |
Fomepizole should not be used more liberally in paracetamol overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; COVID-19; Drug Overdose; Fomepizole; Humans | 2023 |
Fomepizole should be used more liberally in paracetamol overdose.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fomepizole; Humans | 2023 |
Developing new antidotes for poisons with existing effective treatments: a case study of fomepizole in paracetamol poisoning.
Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Fomepizole; Humans; Mice; Poisons | 2023 |