fmrfamide and tyrosyl-prolyl-leucyl-glycinamide

fmrfamide has been researched along with tyrosyl-prolyl-leucyl-glycinamide* in 1 studies

Other Studies

1 other study(ies) available for fmrfamide and tyrosyl-prolyl-leucyl-glycinamide

Article	Year
Inhibitory influences of FMRFamide and PLG on stress-induced opioid analgesia and activity. Brain research, 1986, May-07, Volume: 372, Issue:2 The effects of i.c.v. administration of the peptide FMRFamide (Phe-Met-Arg-Phe-NH2), as well as i.p. injections of PLG (Pro-Leu-Gly-NH2) and the opiate antagonist, naloxone, on immobilization-induced analgesia and locomotor activity were examined in CF-1 and C57BL strains of mice. Both naloxone (1.0 mg/kg) and FMRFamide (0.10-1.0 microgram) blocked the experimentally induced analgesia and activity, whereas PLG (0.10-10 mg/kg) suppressed only analgesia. These results indicate that FMRFamide (or FMRFamide-like neuropeptides) and PLG may function as differential antagonists of the behavioral and physiological consequences of endogenous opioid activation. Topics: Animals; Brain; Endorphins; FMRFamide; Mice; Mice, Inbred C57BL; Motor Activity; MSH Release-Inhibiting Hormone; Oligopeptides; Pain; Restraint, Physical; Stress, Physiological	1986

Article

Year

Inhibitory influences of FMRFamide and PLG on stress-induced opioid analgesia and activity.

Brain research, 1986, May-07, Volume: 372, Issue:2

The effects of i.c.v. administration of the peptide FMRFamide (Phe-Met-Arg-Phe-NH2), as well as i.p. injections of PLG (Pro-Leu-Gly-NH2) and the opiate antagonist, naloxone, on immobilization-induced analgesia and locomotor activity were examined in CF-1 and C57BL strains of mice. Both naloxone (1.0 mg/kg) and FMRFamide (0.10-1.0 microgram) blocked the experimentally induced analgesia and activity, whereas PLG (0.10-10 mg/kg) suppressed only analgesia. These results indicate that FMRFamide (or FMRFamide-like neuropeptides) and PLG may function as differential antagonists of the behavioral and physiological consequences of endogenous opioid activation.

Topics: Animals; Brain; Endorphins; FMRFamide; Mice; Mice, Inbred C57BL; Motor Activity; MSH Release-Inhibiting Hormone; Oligopeptides; Pain; Restraint, Physical; Stress, Physiological

1986