fluvoxamine and carbamazepine-epoxide

fluvoxamine has been researched along with carbamazepine-epoxide* in 1 studies

Trials

1 trial(s) available for fluvoxamine and carbamazepine-epoxide

ArticleYear
Carbamazepine coadministration with fluoxetine or fluvoxamine.
    Therapeutic drug monitoring, 1993, Volume: 15, Issue:3

    To study the potential interaction between carbamazepine (CBZ) and selective serotonin reuptake inhibitors, fluoxetine (20 mg/day) and fluvoxamine (100 mg/day) were administered for 3 weeks to eight and seven epileptic patients, respectively, on chronic CBZ treatment. No significant changes in steady-state plasma concentrations of CBZ and its active metabolite, carbamazepine-10,11-epoxide (CBZ-E) occurred, suggesting that CBZ metabolism is probably not affected by fluoxetine or fluvoxamine administration.

    Topics: Adult; Carbamazepine; Depression; Drug Interactions; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged

1993