flutamide and tamoxifen

flutamide has been researched along with tamoxifen in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-199011 (11.83)18.7374
1990's24 (25.81)18.2507
2000's35 (37.63)29.6817
2010's22 (23.66)24.3611
2020's1 (1.08)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Allan, M; Besterman, JM; Déziel, R; Goulet, AC; Manku, S; Nguyen, H; Nguyen, N; Petschner, AJ; Rahil, G; Robert Macleod, A; Robert, MF; Styhler, S; Therrien, E; Wahhab, A1
Bellavance, E; Luu-The, V; Poirier, D1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dreicer, R; Wilding, G1
Kinzler, SL; Koike, TI; Marks, PA; Robinzon, B; Sayag, N1
Bottjer, SW; Hewer, SJ1
Arnon, E; el Halawani, ME; Grimm, VE; Robinzon, B; Sayag, N; Snapir, N2
de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R1
Concolino, G; Conti, C; Di Silverio, F; Lubrano, C; Petrangeli, E; Sciarra, F; Toscano, V1
Hammer, RP1
Alexandre, C; Balthazart, J2
Almeida, OF; Schulz, R1
Brinck-Johnsen, T; Lhoste, EF; Longnecker, DS; Roebuck, BD1
Benz, C; Hollander, C; Miller, B1
Boublil, JL; Cavaglione, G; Kather, R; Namer, M1
Lax, ER; Peetz, A; Plasczyk, H; Rumstadt, F; Schriefers, H1
Messiha, FS1
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L1
Burger, CW; Greggi, S; Kenemans, P; van der Vange, N; Vermorken, JB1
Giannoulis, G; Hadziyannis, SJ; Manesis, EK; Vafiadou, I; Zoumboulis, P1
Aguilar, R; Bellido, C; Sánchez-Criado, JE; Tébar, M1
Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A1
Farley, MJ; Zimmerberg, B1
Brentani, MM; Escaleira, MT; Sonohara, S1
Aguilar, E; Pinilla, L; Tena-Sempere, M1
Bellido, C; Galiot, F; Gonzalez, D; Sánchez-Criado, JE; Tébar, M1
Brentani, MM; Liberato, MH; Sonohara, S1
Aguilar, R; Gaytán, F; Ruiz, A; Sánchez-Criado, JE; Tébar, AM1
Aichberger, A; Krebs, D; Werner, A1
Gurpide, E; Markiewicz, L1
Lowe, FC; Staiman, VR1
Rai, U1
Amir-Zaltsman, Y; Jaffe, A; Knoll, E; Kohen, F; Somjen, D; Stern, N1
Handa, RJ; Wilson, ME1
Richie, JP1
Leung, SW; Man, RY; Quan, A; Teoh, H1
Damien, E; Lanyon, LE; Price, JS1
Kritzer, MF; Pugach, I1
Isobe, N; Kaneko, H; Komai, K; Nagahori, H; Saito, K; Tomigahara, Y1
Aruldhas, MM; Banu, KS; Govindarajulu, P1
Barker, JL; Chang, YH; Li, Bs; Ma, W; Rubinow, DR; Zhang, L; Zhao, W1
Han, SY; Kang, IH; Kim, HS; Kim, IY; Kim, TS; Moon, HJ; Park, KL; Seok, JH; Shin, JH1
Aruldhas, MM; Banu, SK; Govindarajulu, P1
Leung, G; Tsao, SW; Wong, YC1
Almkvist, A; Ekman, J; Gustafsson, JA; Saji, S; Wang, L; Warner, M; Weihua, Z1
Butler, R; Darrington, RS; Gallo, JM; Leigh, PN; McPhaul, MJ1
Christian, AL; Edwards, EM; Gruman, LM; Hendrix, MJ; Khalkhali-Ellis, Z; Kirschmann, DA; Norwood, LE; Rezaie-Thompson, M; Seftor, RE; Vasef, MA1
Nakajima, A; Sekihara, H; Takahashi, H1
Haldy, ME; Handa, RJ; Lund, TD; Munson, DJ1
Mi, Y; Zhang, C1
Babiak, I; Bopopi, JM; Kestemont, P; Leprieur, F; Mandiki, SN1
Chen, D; Cui, S; Goldstein, RS; Liu, J1
Liu, H; Mi, Y; Tang, X; Zeng, W; Zhang, C1
Choi, SH; Kim, YU; Kwon, HC; Kwon, JY; Son, SO1
Clulow, J; Hansen, LA; Jones, RC1
Grossi, P; Kanter, Rd; Monaci, S; Monshouwer, M; Turlizzi, E; Vignati, L1
Handa, RJ; Hinds, LR; Lund, TD1
Bottero, S; Kloas, W; Lutz, I; Mandich, A; Urbatzka, R1
Gupta, V; Singh, SM2
Cao, A; Zhang, C1
Bottero, S; Cevasco, A; Kloas, W; Mandich, A; Massari, A; Pedemonte, F; Urbatzka, R1
Fernández-Guasti, A; Phillips-Farfán, BV; Romano-Torres, M1
De, PK; Srikantan, S1
Calado, RT; Kajigaya, S; Regal, JA; Stratakis, CA; Wilkerson, KL; Yewdell, WT; Young, NS1
Campos, SG; Corradi, LS; Custodio, AM; Góes, RM; Gonçalves, BF; Santos, FC; Scarano, WR; Taboga, SR; Vilamaior, PS1
Bradley, AJ; Feay, N; Geiser, F; McAllan, BM1
Campos, SG; Góes, RM; Gonçalves, BF; Scarano, WR; Taboga, SR1
Dlugaiczyk, J; Schick, B; Wendler, O1
Inagaki, H; Mori, Y1
Chen, L; Liu, R; Ma, D; Wu, Y1
Cai, Y; Chew, C; Muñoz, F; Sengelaub, DR1
Honda, H; Ito, Y; Kawamoto, T; Morita, O1
Alves, A; Gouveia, TIA; Mota, IH; Santos, MSF; Silva, AMT1

Reviews

3 review(s) available for flutamide and tamoxifen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Steroid hormone agonists and antagonists in the treatment of cancer.
    Cancer investigation, 1992, Volume: 10, Issue:1

    Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Epidermal Growth Factor; Estrogen Antagonists; Estrogens; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Flutamide; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Platelet-Derived Growth Factor; Prostatic Neoplasms; Receptors, Estrogen; Tamoxifen; Transforming Growth Factor beta

1992
Anti-androgens and other hormonal therapies for prostate cancer.
    Urology, 1999, Volume: 54, Issue:6A Suppl

    Topics: Androgen Antagonists; Androgens; Anilides; Biomarkers, Tumor; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds

1999

Trials

3 trial(s) available for flutamide and tamoxifen

ArticleYear
Effects of two different medical treatments on dihydrotestosterone content and androgen receptors in human benign prostatic hyperplasia.
    Journal of steroid biochemistry, 1988, Volume: 30, Issue:1-6

    Topics: Androgen Antagonists; Anilides; Cell Nucleus; Cyproterone; Cyproterone Acetate; Cytosol; Dihydrotestosterone; Flutamide; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Tamoxifen

1988
Treatment of hepatocellular carcinoma with combined suppression and inhibition of sex hormones: a randomized, controlled trial.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6

    Topics: Analysis of Variance; Androgens; Carcinoma, Hepatocellular; Double-Blind Method; Drug Therapy, Combination; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Liver Neoplasms; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Placebos; Probability; Survival Rate; Tamoxifen; Time Factors; Triptorelin Pamoate

1995
Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Flutamide; Humans; Leuprolide; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Tamoxifen; Treatment Outcome

2004

Other Studies

87 other study(ies) available for flutamide and tamoxifen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).
    Bioorganic & medicinal chemistry letters, 2009, Feb-15, Volume: 19, Issue:4

    Topics: Amides; Combinatorial Chemistry Techniques; Molecular Structure; Protein-Arginine N-Methyltransferases; Pyrazoles; Thiophenes

2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Embryonic differentiation of sexual dimorphism in vasotocin and mesotocin levels in chickens.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Animals; Aromatase Inhibitors; Brain Chemistry; Chick Embryo; Chickens; Estradiol; Female; Flutamide; Male; Oxytocin; Radioimmunoassay; Sex Characteristics; Sex Differentiation; Tamoxifen; Vasotocin

1992
Castration and antisteroid treatment impair vocal learning in male zebra finches.
    Journal of neurobiology, 1992, Volume: 23, Issue:4

    Topics: Aging; Androgen Antagonists; Animals; Birds; Estrogen Antagonists; Female; Flutamide; Learning; Male; Orchiectomy; Stereotyped Behavior; Tamoxifen; Vocalization, Animal

1992
Sexual differentiation of copulatory behaviour in the male chick requires gonadal steroids.
    British poultry science, 1991, Volume: 32, Issue:3

    Topics: Animals; Aromatase Inhibitors; Chick Embryo; Estradiol; Female; Flutamide; Immune Sera; Luteinizing Hormone; Male; Nitromifene; Sex Differentiation; Sexual Behavior, Animal; Tamoxifen; Testosterone

1991
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured

1991
Embryonic sex steroids affect mating behavior and plasma LH in adult chickens.
    Physiology & behavior, 1989, Volume: 45, Issue:6

    Topics: Androstatrienes; Animals; Chickens; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Luteinizing Hormone; Male; Orchiectomy; Pregnancy; Prenatal Exposure Delayed Effects; Sex Differentiation; Sexual Behavior, Animal; Tamoxifen

1989
Opiate receptor ontogeny in the rat medial preoptic area is androgen-dependent.
    Neuroendocrinology, 1988, Volume: 48, Issue:4

    Topics: Androgens; Animals; Dihydrotestosterone; Estrogens; Female; Flutamide; Male; Naloxone; Neurons; Oils; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Opioid; Tamoxifen

1988
Inhibition of testosterone metabolism in the brain and cloacal gland of the quail by specific inhibitors and antihormones.
    The Journal of endocrinology, 1987, Volume: 112, Issue:2

    Topics: Androgen Antagonists; Androstanes; Androstatrienes; Animals; Azasteroids; Cloaca; Coturnix; Cyproterone; Cyproterone Acetate; Estrogen Antagonists; Flutamide; Hypothalamus; Male; Nitromifene; Quail; Tamoxifen; Testosterone

1987
Effects of metabolism inhibitors, antiestrogens and antiandrogens on the androgen and estrogen induced sexual behavior in Japanese quail.
    Physiology & behavior, 1986, Volume: 38, Issue:4

    Topics: Androgens; Androstatrienes; Animals; Coturnix; Cyproterone; Cyproterone Acetate; Diethylstilbestrol; Estrogens; Flutamide; Male; Orchiectomy; Quail; Sexual Behavior, Animal; Tamoxifen; Testosterone

1986
Sexual differentiation of the luteinizing hormone response of neonatal rats to the narcotic antagonist naloxone: critical role of estrogen receptors.
    Biology of reproduction, 1988, Volume: 39, Issue:5

    Topics: Animals; Animals, Newborn; Female; Flutamide; Luteinizing Hormone; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sex Characteristics; Tamoxifen

1988
Effect of castration and hormone replacement on azaserine-induced pancreatic carcinogenesis in male and female Fischer rats.
    Carcinogenesis, 1987, Volume: 8, Issue:5

    Topics: Animals; Azaserine; Castration; Estradiol; Female; Flutamide; Male; Organ Size; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344; Sex Factors; Tamoxifen; Testosterone

1987
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
    Cancer research, 1986, Volume: 46, Issue:5

    Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen

1986
[Cancer of the prostate: new hormone therapies].
    Bulletin du cancer, 1986, Volume: 73, Issue:1

    Topics: Androgen Antagonists; Cyproterone; Flutamide; Humans; Ketoconazole; Male; Medroxyprogesterone; Megestrol; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Tamoxifen

1986
Antagonistic action of estrogens, flutamide, and human growth hormone on androgen-induced changes in the activities of some enzymes of hepatic steroid metabolism in the rat.
    Endocrinology, 1983, Volume: 113, Issue:3

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Anilides; Animals; Castration; Estrogen Antagonists; Estrogens; Female; Flutamide; Growth Hormone; Male; Microsomes, Liver; Nafoxidine; Rats; Rats, Inbred Strains; Steroids; Tamoxifen

1983
Steroidal actions and voluntary drinking of ethanol by male and female rats.
    Progress in biochemical pharmacology, 1981, Volume: 18

    Topics: Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Flutamide; Liver; Male; Rats; Rats, Inbred Strains; Tamoxifen

1981
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
    Journal of cancer research and clinical oncology, 1995, Volume: 121, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured

1995
Experience with hormonal therapy in advanced epithelial ovarian cancer.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carcinoma; Estrogen Antagonists; Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteolytic Agents; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Middle Aged; Ovarian Neoplasms; Progesterone Congeners; Remission Induction; Survival Rate; Tamoxifen; Triptorelin Pamoate

1995
Inappropriate ovarian feedback in basal gonadotropin secretion in 4-day cyclic rat treated with mifepristone: role of endogenous estradiol.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:6

    Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Estradiol; Feedback; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropins; Luteinizing Hormone; Mifepristone; Ovariectomy; Ovary; Progesterone; Radioimmunoassay; Rats; Rats, Wistar; Tamoxifen; Testosterone; Time Factors

1994
5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
    British journal of cancer, 1994, Volume: 70, Issue:6

    Topics: Androstenediol; Breast Neoplasms; Cell Division; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1994
Sex differences in anxiety behavior in rats: role of gonadal hormones.
    Physiology & behavior, 1993, Volume: 54, Issue:6

    Topics: Animals; Animals, Newborn; Anxiety; Appetitive Behavior; Arousal; Body Weight; Conditioning, Operant; Discrimination Learning; Female; Flutamide; Gonadal Steroid Hormones; Male; Mental Recall; Orientation; Rats; Receptors, GABA-A; Tamoxifen

1993
Sex steroids induced up-regulation of 1,25-(OH)2 vitamin D3 receptors in T 47D breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:4

    Topics: Breast Neoplasms; Calcitriol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Androgen; Receptors, Calcitriol; Receptors, Estrogen; Receptors, Steroid; Tamoxifen; Tumor Cells, Cultured; Up-Regulation

1993
Follicle-stimulating hormone and luteinizing hormone secretion in male rats orchidectomized or injected with ethylene dimethane sulfonate.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Chorionic Gonadotropin; Estradiol; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Orchiectomy; Rats; Rats, Wistar; Sertoli Cells; Tamoxifen; Testis; Testosterone

1993
Hypothalamus-pituitary-ovarian axis in cyclic rats lacking progesterone actions.
    Biology of reproduction, 1993, Volume: 48, Issue:4

    Topics: Amino Acid Sequence; Animals; Estradiol; Estrus; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Mifepristone; Molecular Sequence Data; Ovariectomy; Ovary; Progesterone; Rats; Rats, Wistar; Tamoxifen; Testosterone

1993
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1993, Volume: 14, Issue:1

    Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regulation; Estradiol; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Tumor Cells, Cultured

1993
RU486-treated rats show endocrine and morphological responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies.
    Biology of reproduction, 1996, Volume: 55, Issue:6

    Topics: Androgen Antagonists; Animals; Bromocriptine; Disease Models, Animal; Dopamine Agonists; Estrogen Antagonists; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Mifepristone; Ovary; Ovulation; Polycystic Ovary Syndrome; Progesterone; Rats; Rats, Wistar; Tamoxifen

1996
[Does interferon-alpha enhance the effect of tamoxifen-medroxyprogesterone acetate and hydroxyflutamide on in vitro tumor cells?].
    Zentralblatt fur Gynakologie, 1996, Volume: 118, Issue:11

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Flutamide; Humans; Interferon-alpha; Medroxyprogesterone Acetate; Ovarian Neoplasms; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:4

    Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured

1997
Tamoxifen for flutamide/finasteride-induced gynecomastia.
    Urology, 1997, Volume: 50, Issue:6

    Topics: Aged; Androgen Antagonists; Drug Evaluation; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Finasteride; Flutamide; Gynecomastia; Humans; Male; Middle Aged; Prostatic Neoplasms; Tamoxifen; Testosterone; Time Factors

1997
Sex steroid hormones modulate the activation of murine peritoneal macrophages: receptor mediated modulation.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1998, Volume: 119, Issue:2

    Topics: Animals; Castration; Cyproterone Acetate; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mifepristone; Nitrites; Progesterone; Receptors, Steroid; Tamoxifen; Testosterone

1998
Effects of gonadal steroids and their antagonists on DNA synthesis in human vascular cells.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:1

    Topics: Analysis of Variance; Androgen Antagonists; Antibodies, Monoclonal; Cell Division; Cell Line; Cells, Cultured; Creatine Kinase; Dihydrotestosterone; DNA; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Flutamide; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Piperidines; Platelet-Derived Growth Factor; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Thymidine

1998
Direct actions of gonadal steroid hormones on FSH secretion and expression in the infantile female rat.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 66, Issue:1-2

    Topics: Animals; Animals, Newborn; Cells, Cultured; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gene Expression Regulation; Gonadal Steroid Hormones; Gonadotropins; Luteinizing Hormone; Microscopy; Pituitary Gland; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroids; Tamoxifen

1998
Differential effects of 17beta-estradiol and testosterone on the contractile responses of porcine coronary arteries.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Coronary Vessels; Cycloheximide; Cyproterone; Dactinomycin; Dose-Response Relationship, Drug; Endothelin-1; Estradiol; Estrogen Antagonists; Female; Flutamide; Fulvestrant; In Vitro Techniques; Isotonic Solutions; Male; Potassium Chloride; Receptors, Estrogen; Serotonin; Swine; Tamoxifen; Testosterone; Vasoconstriction

2000
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:11

    Topics: Androgen Antagonists; Androstenedione; Animals; Antibodies; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flutamide; Fulvestrant; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Stress, Mechanical; Tamoxifen; Testosterone; Thymidine

2000
Administration of tamoxifen but not flutamide to hormonally intact, adult male rats mimics the effects of short-term gonadectomy on the catecholamine innervation of the cerebral cortex.
    The Journal of comparative neurology, 2001, Mar-19, Volume: 431, Issue:4

    Topics: Animals; Axons; Body Weight; Cerebral Cortex; Dopamine; Dopamine beta-Hydroxylase; Flutamide; Male; Muscle, Skeletal; Neurons; Orchiectomy; Organ Size; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Tyrosine 3-Monooxygenase

2001
Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen.
    Toxicology, 2001, May-11, Volume: 162, Issue:2

    Topics: Alpha-Globulins; Animals; Benzhydryl Compounds; DDT; Dieldrin; Diethylstilbestrol; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogen Antagonists; Flutamide; Genistein; Injections, Intraperitoneal; Isoflavones; Liver; Male; Organ Size; Oxidation-Reduction; Phenols; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tamoxifen; Testis

2001
Testosterone and estradiol have specific differential modulatory effect on the proliferation of human thyroid papillary and follicular carcinoma cell lines independent of TSH action.
    Endocrine pathology, 2001,Fall, Volume: 12, Issue:3

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Carcinoma, Papillary, Follicular; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Estrogen Antagonists; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Tamoxifen; Testosterone; Thymidine; Thyroid Neoplasms; Thyrotropin; Tritium; Tumor Cells, Cultured

2001
Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways.
    Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2

    Topics: Androgen Antagonists; Animals; Apoptosis; Chromones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fetal Proteins; Flutamide; Morpholines; Nerve Tissue Proteins; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen; Telencephalon

2002
Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 67, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Diethylstilbestrol; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Estrous Cycle; Female; Flutamide; Hormone Antagonists; Hormones; Injections, Subcutaneous; Organ Size; Rats; Rats, Sprague-Dawley; Sexual Maturation; Tamoxifen; Testosterone; Toxicity Tests; Vagina

2002
Testosterone and estradiol differentially regulate TSH-induced thyrocyte proliferation in immature and adult rats.
    Steroids, 2002, Volume: 67, Issue:7

    Topics: Aging; Animals; Cell Division; Estradiol; Estrogen Antagonists; Female; Flutamide; In Vitro Techniques; Male; Rats; Rats, Wistar; Tamoxifen; Testosterone; Thyroid Gland; Thyrotropin

2002
The effect of flutamide and tamoxifen on sex hormone-induced mammary carcinogenesis and pituitary adenoma.
    Breast cancer research and treatment, 2002, Volume: 72, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogenicity Tests; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Pituitary Gland; Prolactinoma; Rats; Tamoxifen; Testosterone

2002
Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus.
    Biology of reproduction, 2002, Volume: 67, Issue:2

    Topics: Androgen Antagonists; Animals; Blotting, Western; Cell Division; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Flutamide; Immunohistochemistry; Insulin-Like Growth Factor I; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Uterus

2002
Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells.
    Neuroreport, 2002, Nov-15, Volume: 13, Issue:16

    Topics: Androgen Antagonists; Animals; Blotting, Western; Cell Line; Cyproterone Acetate; Estrogen Antagonists; Flutamide; Ligands; Mice; Microscopy, Fluorescence; Muscular Atrophy; Muscular Atrophy, Spinal; Neuroblastoma; Peptides; Receptors, Androgen; Tamoxifen; Testosterone; Transfection

2002
Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-15, Volume: 10, Issue:2

    Topics: Actins; Adult; Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytoplasm; Cytosol; Electrophoresis, Polyacrylamide Gel; Flutamide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Hormones; Humans; Immunohistochemistry; Luciferases; Middle Aged; Models, Genetic; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Serpins; Tamoxifen

2004
Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:3

    Topics: Adult; Apoptosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flow Cytometry; Flutamide; Humans; Lymphocytes; Male; Middle Aged; Staurosporine; Tamoxifen

2004
Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse.
    Neuroscience letters, 2004, Jul-15, Volume: 365, Issue:1

    Topics: Androgen Antagonists; Animals; Corticosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Flutamide; Hypothalamo-Hypophyseal System; Male; Mice; Orchiectomy; Pituitary-Adrenal System; Receptors, Estrogen; Restraint, Physical; Stress, Psychological; Tamoxifen

2004
Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens.
    Toxicology letters, 2005, Feb-15, Volume: 155, Issue:2

    Topics: Androgen Antagonists; Animals; Antioxidants; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Chick Embryo; Chlorodiphenyl (54% Chlorine); Coculture Techniques; Culture Media, Serum-Free; Estrogen Antagonists; Flutamide; Germ Cells; Hormones; Male; Sertoli Cells; Tamoxifen; Testis; Vitamin E

2005
Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles.
    Steroids, 2005, Volume: 70, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Endocrine Glands; Estradiol; Fadrozole; Female; Flutamide; Gonadal Steroid Hormones; Growth Hormone; Hormone Antagonists; Male; Perches; Sex Characteristics; Structure-Activity Relationship; Tamoxifen; Testosterone

2005
Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo.
    Brain research. Developmental brain research, 2005, Mar-22, Volume: 155, Issue:1

    Topics: Androgen Antagonists; Animals; Apoptosis; Body Patterning; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Chick Embryo; Dose-Response Relationship, Drug; Embryonic Structures; Estradiol; Estrogen Antagonists; Flutamide; Ganglia, Spinal; Gonadal Steroid Hormones; Neurons, Afferent; Sex Characteristics; Tamoxifen; Testosterone

2005
Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens.
    Domestic animal endocrinology, 2005, Volume: 28, Issue:4

    Topics: Animals; Chick Embryo; Coculture Techniques; Female; Flutamide; Hormone Antagonists; Immunohistochemistry; Letrozole; Microscopy, Phase-Contrast; Nitriles; Ovary; Ovum; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-kit; Tamoxifen; Testosterone; Triazoles

2005
Androgen action on hepatic vitellogenin synthesis in the eel, Anguilla japonica is suppressed by an androgen receptor antagonist.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 96, Issue:2

    Topics: Androgen Receptor Antagonists; Anguilla; Animals; Estradiol; Female; Flutamide; Growth Hormone; Hepatocytes; Liver; Male; Methyltestosterone; Tamoxifen; Vitellogenins

2005
Perturbation of fluid reabsorption in the efferent ducts of the rat by testosterone propionate, 17beta-oestradiol 3-benzoate, flutamide and tamoxifen.
    International journal of andrology, 1997, Volume: 20, Issue:5

    Topics: Androgen Antagonists; Animals; Body Fluids; Epididymis; Estradiol; Estrogen Receptor Modulators; Flutamide; Male; Organ Size; Rats; Rats, Wistar; Tamoxifen; Testosterone Propionate

1997
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
    Toxicology, 2005, Dec-15, Volume: 216, Issue:2-3

    Topics: Adenosine Triphosphate; Albendazole; Amitriptyline; Animals; Buthionine Sulfoximine; Carbamazepine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromans; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flutamide; Glutathione; Humans; Isoniazid; Microsomes; Ochratoxins; Piperazines; Quinidine; Substrate Specificity; Tamoxifen; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Toxicity Tests; Triazolam; Troglitazone; Xenobiotics

2005
The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Feb-01, Volume: 26, Issue:5

    Topics: Androgen Antagonists; Androgens; Androstane-3,17-diol; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Flutamide; Hypothalamo-Hypophyseal System; Immobilization; Male; Neurons; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tamoxifen

2006
Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2007, Volume: 144, Issue:4

    Topics: Androgen Antagonists; Androgens; Animals; Biomarkers; Dihydrotestosterone; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Flutamide; Italy; Male; Prealbumin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rivers; RNA, Messenger; Tamoxifen; Testosterone; Transferrin; Vitellogenins; Water Pollutants, Chemical; Xenopus laevis

2007
Gender dimorphism in the myeloid differentiation of bone marrow precursor cells in a murine host bearing a T cell lymphoma.
    Journal of reproductive immunology, 2007, Volume: 74, Issue:1-2

    Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Estrogen Antagonists; Estrogens; Female; Flutamide; Lymphoma, T-Cell; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred BALB C; Myelopoiesis; Nitric Oxide; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics; Tamoxifen; Tumor Suppressor Protein p53

2007
Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons.
    Endocrine, 2007, Volume: 31, Issue:2

    Topics: Androgens; Animals; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Chick Embryo; Estrogens; Female; Flutamide; Hormone Antagonists; Hypothalamus; Letrozole; Male; Neurons; Nitriles; Sex Characteristics; Tamoxifen; Triazoles

2007
Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2008, Volume: 147, Issue:2

    Topics: Animals; Endocrine Disruptors; Environmental Monitoring; Ethinyl Estradiol; Female; Flutamide; Male; Methyltestosterone; Ovary; Tamoxifen; Testis; Xenopus laevis

2008
Anabolic androgens restore mating after sexual satiety in male rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:3

    Topics: Anabolic Agents; Androgens; Animals; Dihydrotestosterone; Ejaculation; Estradiol; Female; Flutamide; gamma-Aminobutyric Acid; Male; Nandrolone; Nandrolone Decanoate; Rats; Rats, Wistar; Receptors, Estrogen; Sexual Behavior, Animal; Tamoxifen; Testosterone

2008
Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma.
    Anti-cancer drugs, 2008, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cisplatin; Doxorubicin; Female; Flutamide; Interferon-gamma; Interleukin-2; Lymphoma, T-Cell; Male; Mice; Mice, Inbred BALB C; Receptors, Interleukin-2; Sex Characteristics; Tamoxifen; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A

2008
Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters.
    General and comparative endocrinology, 2008, Sep-15, Volume: 158, Issue:3

    Topics: Age Factors; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Animals, Newborn; Blotting, Western; Cricetinae; Estrogen Antagonists; Estrogens; Female; Flutamide; Lacrimal Apparatus; Lipocalin 1; Male; Mice; Rats; Receptors, Estrogen; Receptors, Odorant; Sex Factors; Tamoxifen

2008
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
    Blood, 2009, Sep-10, Volume: 114, Issue:11

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibitors; Dyskeratosis Congenita; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Female; Flutamide; Gene Expression Regulation, Enzymologic; Hematopoietic Stem Cells; Heterozygote; Humans; Letrozole; Lymphocytes; Male; Mutation; Nitriles; Receptors, Androgen; Tamoxifen; Telomerase; Triazoles

2009
Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity.
    International journal of experimental pathology, 2010, Volume: 91, Issue:5

    Topics: Aging; Androgen Antagonists; Androgen-Insensitivity Syndrome; Androgens; Animals; Apoptosis; Body Weight; Estradiol; Estrogen Antagonists; Flutamide; Gerbillinae; Male; Orchiectomy; Organ Size; Prostate; Tamoxifen; Testosterone

2010
The influence of reproductive hormones on the torpor patterns of the marsupial Sminthopsis macroura: bet-hedging in an unpredictable environment.
    General and comparative endocrinology, 2012, Nov-01, Volume: 179, Issue:2

    Topics: Adaptation, Physiological; Animals; Basal Metabolism; Body Temperature; Body Temperature Regulation; Body Weight; Circadian Rhythm; Estrogens; Female; Flutamide; Hormone Antagonists; Male; Marsupialia; Mifepristone; Photoperiod; Progesterone; Reproduction; Tamoxifen; Testosterone

2012
Phenotypic and metabolic aspects of prostatic epithelial cells in aged gerbils after antisteroidal therapy: turnover in the state of chromatin condensation and androgen-independent cell replacement.
    Acta histochemica, 2014, Volume: 116, Issue:1

    Topics: Aging; Androgen Antagonists; Androgens; Animals; Cell Proliferation; Chromatin Assembly and Disassembly; Epithelial Cells; Estrogen Antagonists; Flutamide; Gerbillinae; Male; Phenotype; Prostate; Tamoxifen

2014
Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators.
    Head & neck, 2014, Volume: 36, Issue:11

    Topics: Adolescent; Angiofibroma; Antineoplastic Agents, Hormonal; Cell Proliferation; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Nasal Mucosa; Nose Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Tamoxifen; Tumor Cells, Cultured; Young Adult

2014
Relationship between 22-kHz calls and testosterone in male rats.
    Hormones and behavior, 2014, Volume: 65, Issue:1

    Topics: Androgen Antagonists; Animal Communication; Animals; Cholesterol; Data Interpretation, Statistical; Estrogen Antagonists; Flutamide; Male; Orchiectomy; Physical Stimulation; Rats; Rats, Wistar; Stress, Psychological; Tamoxifen; Testosterone; Vocalization, Animal

2014
Evaluation of the removal of antiestrogens and antiandrogens via ozone and granular activated carbon using bioassay and fluorescent spectroscopy.
    Chemosphere, 2016, Volume: 153

    Topics: Adsorption; Androgen Antagonists; Biological Assay; Charcoal; Coloring Agents; Endocrine Disruptors; Estrogen Receptor Modulators; Flutamide; Ozone; Spectrum Analysis; Tamoxifen; Wastewater; Water Purification

2016
Neuroprotective effects of testosterone metabolites and dependency on receptor action on the morphology of somatic motoneurons following the death of neighboring motoneurons.
    Developmental neurobiology, 2017, Volume: 77, Issue:6

    Topics: Androgen Antagonists; Animals; Cell Death; Cholera Toxin; Dendrites; Dihydrotestosterone; Flutamide; Horseradish Peroxidase; Male; Motor Neurons; Muscle, Skeletal; Nerve Net; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Tamoxifen; Testosterone

2017
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:4

    Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Humans; Imipramine; Inflammation; Ketoconazole; Liver; Methyltestosterone; Oxidative Stress; Rats; Risk Assessment; Sulindac; Tamoxifen; Toxicogenetics

2017
Are cytostatic drugs in surface waters a potential threat?
    The Science of the total environment, 2022, Dec-20, Volume: 853

    Topics: Child; Chlorambucil; Cyclophosphamide; Cyproterone; Cytostatic Agents; Drinking Water; Environmental Monitoring; Etoposide; Flutamide; Humans; Mycophenolic Acid; Pharmaceutical Preparations; Rivers; Tamoxifen; Water Pollutants, Chemical

2022