flutamide has been researched along with tamoxifen in 93 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (11.83) | 18.7374 |
| 1990's | 24 (25.81) | 18.2507 |
| 2000's | 35 (37.63) | 29.6817 |
| 2010's | 22 (23.66) | 24.3611 |
| 2020's | 1 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Allan, M; Besterman, JM; Déziel, R; Goulet, AC; Manku, S; Nguyen, H; Nguyen, N; Petschner, AJ; Rahil, G; Robert Macleod, A; Robert, MF; Styhler, S; Therrien, E; Wahhab, A | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Dreicer, R; Wilding, G | 1 |
| Kinzler, SL; Koike, TI; Marks, PA; Robinzon, B; Sayag, N | 1 |
| Bottjer, SW; Hewer, SJ | 1 |
| Arnon, E; el Halawani, ME; Grimm, VE; Robinzon, B; Sayag, N; Snapir, N | 2 |
| de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R | 1 |
| Concolino, G; Conti, C; Di Silverio, F; Lubrano, C; Petrangeli, E; Sciarra, F; Toscano, V | 1 |
| Hammer, RP | 1 |
| Alexandre, C; Balthazart, J | 2 |
| Almeida, OF; Schulz, R | 1 |
| Brinck-Johnsen, T; Lhoste, EF; Longnecker, DS; Roebuck, BD | 1 |
| Benz, C; Hollander, C; Miller, B | 1 |
| Boublil, JL; Cavaglione, G; Kather, R; Namer, M | 1 |
| Lax, ER; Peetz, A; Plasczyk, H; Rumstadt, F; Schriefers, H | 1 |
| Messiha, FS | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L | 1 |
| Burger, CW; Greggi, S; Kenemans, P; van der Vange, N; Vermorken, JB | 1 |
| Giannoulis, G; Hadziyannis, SJ; Manesis, EK; Vafiadou, I; Zoumboulis, P | 1 |
| Aguilar, R; Bellido, C; Sánchez-Criado, JE; Tébar, M | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A | 1 |
| Farley, MJ; Zimmerberg, B | 1 |
| Brentani, MM; Escaleira, MT; Sonohara, S | 1 |
| Aguilar, E; Pinilla, L; Tena-Sempere, M | 1 |
| Bellido, C; Galiot, F; Gonzalez, D; Sánchez-Criado, JE; Tébar, M | 1 |
| Brentani, MM; Liberato, MH; Sonohara, S | 1 |
| Aguilar, R; Gaytán, F; Ruiz, A; Sánchez-Criado, JE; Tébar, AM | 1 |
| Aichberger, A; Krebs, D; Werner, A | 1 |
| Gurpide, E; Markiewicz, L | 1 |
| Lowe, FC; Staiman, VR | 1 |
| Rai, U | 1 |
| Amir-Zaltsman, Y; Jaffe, A; Knoll, E; Kohen, F; Somjen, D; Stern, N | 1 |
| Handa, RJ; Wilson, ME | 1 |
| Richie, JP | 1 |
| Leung, SW; Man, RY; Quan, A; Teoh, H | 1 |
| Damien, E; Lanyon, LE; Price, JS | 1 |
| Kritzer, MF; Pugach, I | 1 |
| Isobe, N; Kaneko, H; Komai, K; Nagahori, H; Saito, K; Tomigahara, Y | 1 |
| Aruldhas, MM; Banu, KS; Govindarajulu, P | 1 |
| Barker, JL; Chang, YH; Li, Bs; Ma, W; Rubinow, DR; Zhang, L; Zhao, W | 1 |
| Han, SY; Kang, IH; Kim, HS; Kim, IY; Kim, TS; Moon, HJ; Park, KL; Seok, JH; Shin, JH | 1 |
| Aruldhas, MM; Banu, SK; Govindarajulu, P | 1 |
| Leung, G; Tsao, SW; Wong, YC | 1 |
| Almkvist, A; Ekman, J; Gustafsson, JA; Saji, S; Wang, L; Warner, M; Weihua, Z | 1 |
| Butler, R; Darrington, RS; Gallo, JM; Leigh, PN; McPhaul, MJ | 1 |
| Christian, AL; Edwards, EM; Gruman, LM; Hendrix, MJ; Khalkhali-Ellis, Z; Kirschmann, DA; Norwood, LE; Rezaie-Thompson, M; Seftor, RE; Vasef, MA | 1 |
| Nakajima, A; Sekihara, H; Takahashi, H | 1 |
| Haldy, ME; Handa, RJ; Lund, TD; Munson, DJ | 1 |
| Mi, Y; Zhang, C | 1 |
| Babiak, I; Bopopi, JM; Kestemont, P; Leprieur, F; Mandiki, SN | 1 |
| Chen, D; Cui, S; Goldstein, RS; Liu, J | 1 |
| Liu, H; Mi, Y; Tang, X; Zeng, W; Zhang, C | 1 |
| Choi, SH; Kim, YU; Kwon, HC; Kwon, JY; Son, SO | 1 |
| Clulow, J; Hansen, LA; Jones, RC | 1 |
| Grossi, P; Kanter, Rd; Monaci, S; Monshouwer, M; Turlizzi, E; Vignati, L | 1 |
| Handa, RJ; Hinds, LR; Lund, TD | 1 |
| Bottero, S; Kloas, W; Lutz, I; Mandich, A; Urbatzka, R | 1 |
| Gupta, V; Singh, SM | 2 |
| Cao, A; Zhang, C | 1 |
| Bottero, S; Cevasco, A; Kloas, W; Mandich, A; Massari, A; Pedemonte, F; Urbatzka, R | 1 |
| Fernández-Guasti, A; Phillips-Farfán, BV; Romano-Torres, M | 1 |
| De, PK; Srikantan, S | 1 |
| Calado, RT; Kajigaya, S; Regal, JA; Stratakis, CA; Wilkerson, KL; Yewdell, WT; Young, NS | 1 |
| Campos, SG; Corradi, LS; Custodio, AM; Góes, RM; Gonçalves, BF; Santos, FC; Scarano, WR; Taboga, SR; Vilamaior, PS | 1 |
| Bradley, AJ; Feay, N; Geiser, F; McAllan, BM | 1 |
| Campos, SG; Góes, RM; Gonçalves, BF; Scarano, WR; Taboga, SR | 1 |
| Dlugaiczyk, J; Schick, B; Wendler, O | 1 |
| Inagaki, H; Mori, Y | 1 |
| Chen, L; Liu, R; Ma, D; Wu, Y | 1 |
| Cai, Y; Chew, C; Muñoz, F; Sengelaub, DR | 1 |
| Honda, H; Ito, Y; Kawamoto, T; Morita, O | 1 |
| Alves, A; Gouveia, TIA; Mota, IH; Santos, MSF; Silva, AMT | 1 |
3 review(s) available for flutamide and tamoxifen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Steroid hormone agonists and antagonists in the treatment of cancer.
Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Epidermal Growth Factor; Estrogen Antagonists; Estrogens; Female; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Flutamide; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Platelet-Derived Growth Factor; Prostatic Neoplasms; Receptors, Estrogen; Tamoxifen; Transforming Growth Factor beta | 1992 |
Anti-androgens and other hormonal therapies for prostate cancer.
Topics: Androgen Antagonists; Androgens; Anilides; Biomarkers, Tumor; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds | 1999 |
3 trial(s) available for flutamide and tamoxifen
| Article | Year |
|---|---|
Effects of two different medical treatments on dihydrotestosterone content and androgen receptors in human benign prostatic hyperplasia.
Topics: Androgen Antagonists; Anilides; Cell Nucleus; Cyproterone; Cyproterone Acetate; Cytosol; Dihydrotestosterone; Flutamide; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Tamoxifen | 1988 |
Treatment of hepatocellular carcinoma with combined suppression and inhibition of sex hormones: a randomized, controlled trial.
Topics: Analysis of Variance; Androgens; Carcinoma, Hepatocellular; Double-Blind Method; Drug Therapy, Combination; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Liver Neoplasms; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Placebos; Probability; Survival Rate; Tamoxifen; Time Factors; Triptorelin Pamoate | 1995 |
Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Flutamide; Humans; Leuprolide; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Tamoxifen; Treatment Outcome | 2004 |
87 other study(ies) available for flutamide and tamoxifen
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
N-Benzyl-1-heteroaryl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamides as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).
Topics: Amides; Combinatorial Chemistry Techniques; Molecular Structure; Protein-Arginine N-Methyltransferases; Pyrazoles; Thiophenes | 2009 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Embryonic differentiation of sexual dimorphism in vasotocin and mesotocin levels in chickens.
Topics: Animals; Aromatase Inhibitors; Brain Chemistry; Chick Embryo; Chickens; Estradiol; Female; Flutamide; Male; Oxytocin; Radioimmunoassay; Sex Characteristics; Sex Differentiation; Tamoxifen; Vasotocin | 1992 |
Castration and antisteroid treatment impair vocal learning in male zebra finches.
Topics: Aging; Androgen Antagonists; Animals; Birds; Estrogen Antagonists; Female; Flutamide; Learning; Male; Orchiectomy; Stereotyped Behavior; Tamoxifen; Vocalization, Animal | 1992 |
Sexual differentiation of copulatory behaviour in the male chick requires gonadal steroids.
Topics: Animals; Aromatase Inhibitors; Chick Embryo; Estradiol; Female; Flutamide; Immune Sera; Luteinizing Hormone; Male; Nitromifene; Sex Differentiation; Sexual Behavior, Animal; Tamoxifen; Testosterone | 1991 |
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured | 1991 |
Embryonic sex steroids affect mating behavior and plasma LH in adult chickens.
Topics: Androstatrienes; Animals; Chickens; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Luteinizing Hormone; Male; Orchiectomy; Pregnancy; Prenatal Exposure Delayed Effects; Sex Differentiation; Sexual Behavior, Animal; Tamoxifen | 1989 |
Opiate receptor ontogeny in the rat medial preoptic area is androgen-dependent.
Topics: Androgens; Animals; Dihydrotestosterone; Estrogens; Female; Flutamide; Male; Naloxone; Neurons; Oils; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Opioid; Tamoxifen | 1988 |
Inhibition of testosterone metabolism in the brain and cloacal gland of the quail by specific inhibitors and antihormones.
Topics: Androgen Antagonists; Androstanes; Androstatrienes; Animals; Azasteroids; Cloaca; Coturnix; Cyproterone; Cyproterone Acetate; Estrogen Antagonists; Flutamide; Hypothalamus; Male; Nitromifene; Quail; Tamoxifen; Testosterone | 1987 |
Effects of metabolism inhibitors, antiestrogens and antiandrogens on the androgen and estrogen induced sexual behavior in Japanese quail.
Topics: Androgens; Androstatrienes; Animals; Coturnix; Cyproterone; Cyproterone Acetate; Diethylstilbestrol; Estrogens; Flutamide; Male; Orchiectomy; Quail; Sexual Behavior, Animal; Tamoxifen; Testosterone | 1986 |
Sexual differentiation of the luteinizing hormone response of neonatal rats to the narcotic antagonist naloxone: critical role of estrogen receptors.
Topics: Animals; Animals, Newborn; Female; Flutamide; Luteinizing Hormone; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sex Characteristics; Tamoxifen | 1988 |
Effect of castration and hormone replacement on azaserine-induced pancreatic carcinogenesis in male and female Fischer rats.
Topics: Animals; Azaserine; Castration; Estradiol; Female; Flutamide; Male; Organ Size; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344; Sex Factors; Tamoxifen; Testosterone | 1987 |
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen | 1986 |
[Cancer of the prostate: new hormone therapies].
Topics: Androgen Antagonists; Cyproterone; Flutamide; Humans; Ketoconazole; Male; Medroxyprogesterone; Megestrol; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Tamoxifen | 1986 |
Antagonistic action of estrogens, flutamide, and human growth hormone on androgen-induced changes in the activities of some enzymes of hepatic steroid metabolism in the rat.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Anilides; Animals; Castration; Estrogen Antagonists; Estrogens; Female; Flutamide; Growth Hormone; Male; Microsomes, Liver; Nafoxidine; Rats; Rats, Inbred Strains; Steroids; Tamoxifen | 1983 |
Steroidal actions and voluntary drinking of ethanol by male and female rats.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Animals; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Flutamide; Liver; Male; Rats; Rats, Inbred Strains; Tamoxifen | 1981 |
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured | 1995 |
Experience with hormonal therapy in advanced epithelial ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carcinoma; Estrogen Antagonists; Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteolytic Agents; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Middle Aged; Ovarian Neoplasms; Progesterone Congeners; Remission Induction; Survival Rate; Tamoxifen; Triptorelin Pamoate | 1995 |
Inappropriate ovarian feedback in basal gonadotropin secretion in 4-day cyclic rat treated with mifepristone: role of endogenous estradiol.
Topics: Animals; Circadian Rhythm; Dose-Response Relationship, Drug; Estradiol; Feedback; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropins; Luteinizing Hormone; Mifepristone; Ovariectomy; Ovary; Progesterone; Radioimmunoassay; Rats; Rats, Wistar; Tamoxifen; Testosterone; Time Factors | 1994 |
5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
Topics: Androstenediol; Breast Neoplasms; Cell Division; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1994 |
Sex differences in anxiety behavior in rats: role of gonadal hormones.
Topics: Animals; Animals, Newborn; Anxiety; Appetitive Behavior; Arousal; Body Weight; Conditioning, Operant; Discrimination Learning; Female; Flutamide; Gonadal Steroid Hormones; Male; Mental Recall; Orientation; Rats; Receptors, GABA-A; Tamoxifen | 1993 |
Sex steroids induced up-regulation of 1,25-(OH)2 vitamin D3 receptors in T 47D breast cancer cells.
Topics: Breast Neoplasms; Calcitriol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Androgen; Receptors, Calcitriol; Receptors, Estrogen; Receptors, Steroid; Tamoxifen; Tumor Cells, Cultured; Up-Regulation | 1993 |
Follicle-stimulating hormone and luteinizing hormone secretion in male rats orchidectomized or injected with ethylene dimethane sulfonate.
Topics: Aging; Animals; Animals, Newborn; Chorionic Gonadotropin; Estradiol; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Orchiectomy; Rats; Rats, Wistar; Sertoli Cells; Tamoxifen; Testis; Testosterone | 1993 |
Hypothalamus-pituitary-ovarian axis in cyclic rats lacking progesterone actions.
Topics: Amino Acid Sequence; Animals; Estradiol; Estrus; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Mifepristone; Molecular Sequence Data; Ovariectomy; Ovary; Progesterone; Rats; Rats, Wistar; Tamoxifen; Testosterone | 1993 |
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regulation; Estradiol; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
RU486-treated rats show endocrine and morphological responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies.
Topics: Androgen Antagonists; Animals; Bromocriptine; Disease Models, Animal; Dopamine Agonists; Estrogen Antagonists; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Mifepristone; Ovary; Ovulation; Polycystic Ovary Syndrome; Progesterone; Rats; Rats, Wistar; Tamoxifen | 1996 |
[Does interferon-alpha enhance the effect of tamoxifen-medroxyprogesterone acetate and hydroxyflutamide on in vitro tumor cells?].
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Flutamide; Humans; Interferon-alpha; Medroxyprogesterone Acetate; Ovarian Neoplasms; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Estrogenic and progestagenic activities of physiologic and synthetic androgens, as measured by in vitro bioassays.
Topics: Adenocarcinoma; Alkaline Phosphatase; Androgen Antagonists; Androgens; Breast Neoplasms; Cyproterone Acetate; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Flutamide; Gonanes; Humans; Mifepristone; Polyunsaturated Alkamides; Progestins; Tamoxifen; Testosterone; Testosterone Congeners; Tumor Cells, Cultured | 1997 |
Tamoxifen for flutamide/finasteride-induced gynecomastia.
Topics: Aged; Androgen Antagonists; Drug Evaluation; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Finasteride; Flutamide; Gynecomastia; Humans; Male; Middle Aged; Prostatic Neoplasms; Tamoxifen; Testosterone; Time Factors | 1997 |
Sex steroid hormones modulate the activation of murine peritoneal macrophages: receptor mediated modulation.
Topics: Animals; Castration; Cyproterone Acetate; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Mifepristone; Nitrites; Progesterone; Receptors, Steroid; Tamoxifen; Testosterone | 1998 |
Effects of gonadal steroids and their antagonists on DNA synthesis in human vascular cells.
Topics: Analysis of Variance; Androgen Antagonists; Antibodies, Monoclonal; Cell Division; Cell Line; Cells, Cultured; Creatine Kinase; Dihydrotestosterone; DNA; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Flutamide; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Piperidines; Platelet-Derived Growth Factor; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Thymidine | 1998 |
Direct actions of gonadal steroid hormones on FSH secretion and expression in the infantile female rat.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gene Expression Regulation; Gonadal Steroid Hormones; Gonadotropins; Luteinizing Hormone; Microscopy; Pituitary Gland; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroids; Tamoxifen | 1998 |
Differential effects of 17beta-estradiol and testosterone on the contractile responses of porcine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Coronary Vessels; Cycloheximide; Cyproterone; Dactinomycin; Dose-Response Relationship, Drug; Endothelin-1; Estradiol; Estrogen Antagonists; Female; Flutamide; Fulvestrant; In Vitro Techniques; Isotonic Solutions; Male; Potassium Chloride; Receptors, Estrogen; Serotonin; Swine; Tamoxifen; Testosterone; Vasoconstriction | 2000 |
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females.
Topics: Androgen Antagonists; Androstenedione; Animals; Antibodies; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flutamide; Fulvestrant; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Stress, Mechanical; Tamoxifen; Testosterone; Thymidine | 2000 |
Administration of tamoxifen but not flutamide to hormonally intact, adult male rats mimics the effects of short-term gonadectomy on the catecholamine innervation of the cerebral cortex.
Topics: Animals; Axons; Body Weight; Cerebral Cortex; Dopamine; Dopamine beta-Hydroxylase; Flutamide; Male; Muscle, Skeletal; Neurons; Orchiectomy; Organ Size; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Tyrosine 3-Monooxygenase | 2001 |
Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen.
Topics: Alpha-Globulins; Animals; Benzhydryl Compounds; DDT; Dieldrin; Diethylstilbestrol; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogen Antagonists; Flutamide; Genistein; Injections, Intraperitoneal; Isoflavones; Liver; Male; Organ Size; Oxidation-Reduction; Phenols; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tamoxifen; Testis | 2001 |
Testosterone and estradiol have specific differential modulatory effect on the proliferation of human thyroid papillary and follicular carcinoma cell lines independent of TSH action.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Carcinoma, Papillary, Follicular; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Estrogen Antagonists; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Tamoxifen; Testosterone; Thymidine; Thyroid Neoplasms; Thyrotropin; Tritium; Tumor Cells, Cultured | 2001 |
Dehydroepiandrosterone (DHEA) and its sulfated derivative (DHEAS) regulate apoptosis during neurogenesis by triggering the Akt signaling pathway in opposing ways.
Topics: Androgen Antagonists; Animals; Apoptosis; Chromones; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fetal Proteins; Flutamide; Morpholines; Nerve Tissue Proteins; Neurons; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen; Telencephalon | 2002 |
Evaluation of the 20-day pubertal female assay in Sprague-Dawley rats treated with DES, tamoxifen, testosterone, and flutamide.
Topics: Administration, Oral; Animals; Body Weight; Diethylstilbestrol; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Estrous Cycle; Female; Flutamide; Hormone Antagonists; Hormones; Injections, Subcutaneous; Organ Size; Rats; Rats, Sprague-Dawley; Sexual Maturation; Tamoxifen; Testosterone; Toxicity Tests; Vagina | 2002 |
Testosterone and estradiol differentially regulate TSH-induced thyrocyte proliferation in immature and adult rats.
Topics: Aging; Animals; Cell Division; Estradiol; Estrogen Antagonists; Female; Flutamide; In Vitro Techniques; Male; Rats; Rats, Wistar; Tamoxifen; Testosterone; Thyroid Gland; Thyrotropin | 2002 |
The effect of flutamide and tamoxifen on sex hormone-induced mammary carcinogenesis and pituitary adenoma.
Topics: Animals; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogenicity Tests; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Pituitary Gland; Prolactinoma; Rats; Tamoxifen; Testosterone | 2002 |
Involvement of androgen receptor in 17beta-estradiol-induced cell proliferation in rat uterus.
Topics: Androgen Antagonists; Animals; Blotting, Western; Cell Division; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Flutamide; Immunohistochemistry; Insulin-Like Growth Factor I; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Uterus | 2002 |
Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells.
Topics: Androgen Antagonists; Animals; Blotting, Western; Cell Line; Cyproterone Acetate; Estrogen Antagonists; Flutamide; Ligands; Mice; Microscopy, Fluorescence; Muscular Atrophy; Muscular Atrophy, Spinal; Neuroblastoma; Peptides; Receptors, Androgen; Tamoxifen; Testosterone; Transfection | 2002 |
Regulating the tumor suppressor gene maspin in breast cancer cells: a potential mechanism for the anticancer properties of tamoxifen.
Topics: Actins; Adult; Antineoplastic Agents, Hormonal; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytoplasm; Cytosol; Electrophoresis, Polyacrylamide Gel; Flutamide; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Hormones; Humans; Immunohistochemistry; Luciferases; Middle Aged; Models, Genetic; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Serpins; Tamoxifen | 2004 |
Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) inhibit the apoptosis in human peripheral blood lymphocytes.
Topics: Adult; Apoptosis; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flow Cytometry; Flutamide; Humans; Lymphocytes; Male; Middle Aged; Staurosporine; Tamoxifen | 2004 |
Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse.
Topics: Androgen Antagonists; Animals; Corticosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Flutamide; Hypothalamo-Hypophyseal System; Male; Mice; Orchiectomy; Pituitary-Adrenal System; Receptors, Estrogen; Restraint, Physical; Stress, Psychological; Tamoxifen | 2004 |
Toxic and hormonal effects of polychlorinated biphenyls on cultured testicular germ cells of embryonic chickens.
Topics: Androgen Antagonists; Animals; Antioxidants; Cell Count; Cell Proliferation; Cell Survival; Cells, Cultured; Chick Embryo; Chlorodiphenyl (54% Chlorine); Coculture Techniques; Culture Media, Serum-Free; Estrogen Antagonists; Flutamide; Germ Cells; Hormones; Male; Sertoli Cells; Tamoxifen; Testis; Vitamin E | 2005 |
Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles.
Topics: Animals; Dose-Response Relationship, Drug; Endocrine Glands; Estradiol; Fadrozole; Female; Flutamide; Gonadal Steroid Hormones; Growth Hormone; Hormone Antagonists; Male; Perches; Sex Characteristics; Structure-Activity Relationship; Tamoxifen; Testosterone | 2005 |
Effects of male and female sex steroids on the development of normal and the transient Froriep's dorsal root ganglia of the chick embryo.
Topics: Androgen Antagonists; Animals; Apoptosis; Body Patterning; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Proliferation; Chick Embryo; Dose-Response Relationship, Drug; Embryonic Structures; Estradiol; Estrogen Antagonists; Flutamide; Ganglia, Spinal; Gonadal Steroid Hormones; Neurons, Afferent; Sex Characteristics; Tamoxifen; Testosterone | 2005 |
Stimulating effects of androgen on proliferation of cultured ovarian germ cells through androgenic and estrogenic actions in embryonic chickens.
Topics: Animals; Chick Embryo; Coculture Techniques; Female; Flutamide; Hormone Antagonists; Immunohistochemistry; Letrozole; Microscopy, Phase-Contrast; Nitriles; Ovary; Ovum; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-kit; Tamoxifen; Testosterone; Triazoles | 2005 |
Androgen action on hepatic vitellogenin synthesis in the eel, Anguilla japonica is suppressed by an androgen receptor antagonist.
Topics: Androgen Receptor Antagonists; Anguilla; Animals; Estradiol; Female; Flutamide; Growth Hormone; Hepatocytes; Liver; Male; Methyltestosterone; Tamoxifen; Vitellogenins | 2005 |
Perturbation of fluid reabsorption in the efferent ducts of the rat by testosterone propionate, 17beta-oestradiol 3-benzoate, flutamide and tamoxifen.
Topics: Androgen Antagonists; Animals; Body Fluids; Epididymis; Estradiol; Estrogen Receptor Modulators; Flutamide; Male; Organ Size; Rats; Rats, Wistar; Tamoxifen; Testosterone Propionate | 1997 |
An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics.
Topics: Adenosine Triphosphate; Albendazole; Amitriptyline; Animals; Buthionine Sulfoximine; Carbamazepine; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chromans; Coculture Techniques; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flutamide; Glutathione; Humans; Isoniazid; Microsomes; Ochratoxins; Piperazines; Quinidine; Substrate Specificity; Tamoxifen; Tetrazolium Salts; Thiazoles; Thiazolidinediones; Toxicity Tests; Triazolam; Troglitazone; Xenobiotics | 2005 |
The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.
Topics: Androgen Antagonists; Androgens; Androstane-3,17-diol; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Flutamide; Hypothalamo-Hypophyseal System; Immobilization; Male; Neurons; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tamoxifen | 2006 |
Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression.
Topics: Androgen Antagonists; Androgens; Animals; Biomarkers; Dihydrotestosterone; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Flutamide; Italy; Male; Prealbumin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rivers; RNA, Messenger; Tamoxifen; Testosterone; Transferrin; Vitellogenins; Water Pollutants, Chemical; Xenopus laevis | 2007 |
Gender dimorphism in the myeloid differentiation of bone marrow precursor cells in a murine host bearing a T cell lymphoma.
Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Blotting, Western; Bone Marrow Cells; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Estrogen Antagonists; Estrogens; Female; Flutamide; Lymphoma, T-Cell; Macrophage Colony-Stimulating Factor; Macrophages; Male; Mice; Mice, Inbred BALB C; Myelopoiesis; Nitric Oxide; Reverse Transcriptase Polymerase Chain Reaction; Sex Characteristics; Tamoxifen; Tumor Suppressor Protein p53 | 2007 |
Sex-specific effects of androgen and estrogen on proliferation of the embryonic chicken hypothalamic neurons.
Topics: Androgens; Animals; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Chick Embryo; Estrogens; Female; Flutamide; Hormone Antagonists; Hypothalamus; Letrozole; Male; Neurons; Nitriles; Sex Characteristics; Tamoxifen; Triazoles | 2007 |
Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology.
Topics: Animals; Endocrine Disruptors; Environmental Monitoring; Ethinyl Estradiol; Female; Flutamide; Male; Methyltestosterone; Ovary; Tamoxifen; Testis; Xenopus laevis | 2008 |
Anabolic androgens restore mating after sexual satiety in male rats.
Topics: Anabolic Agents; Androgens; Animals; Dihydrotestosterone; Ejaculation; Estradiol; Female; Flutamide; gamma-Aminobutyric Acid; Male; Nandrolone; Nandrolone Decanoate; Rats; Rats, Wistar; Receptors, Estrogen; Sexual Behavior, Animal; Tamoxifen; Testosterone | 2008 |
Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cisplatin; Doxorubicin; Female; Flutamide; Interferon-gamma; Interleukin-2; Lymphoma, T-Cell; Male; Mice; Mice, Inbred BALB C; Receptors, Interleukin-2; Sex Characteristics; Tamoxifen; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2008 |
Sex differences in expression and differential regulation by androgen and estrogen of two odorant-binding tear lipocalins in lacrimal glands of immature hamsters.
Topics: Age Factors; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Animals, Newborn; Blotting, Western; Cricetinae; Estrogen Antagonists; Estrogens; Female; Flutamide; Lacrimal Apparatus; Lipocalin 1; Male; Mice; Rats; Receptors, Estrogen; Receptors, Odorant; Sex Factors; Tamoxifen | 2008 |
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anemia, Aplastic; Aromatase Inhibitors; Dyskeratosis Congenita; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Female; Flutamide; Gene Expression Regulation, Enzymologic; Hematopoietic Stem Cells; Heterozygote; Humans; Letrozole; Lymphocytes; Male; Mutation; Nitriles; Receptors, Androgen; Tamoxifen; Telomerase; Triazoles | 2009 |
Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity.
Topics: Aging; Androgen Antagonists; Androgen-Insensitivity Syndrome; Androgens; Animals; Apoptosis; Body Weight; Estradiol; Estrogen Antagonists; Flutamide; Gerbillinae; Male; Orchiectomy; Organ Size; Prostate; Tamoxifen; Testosterone | 2010 |
The influence of reproductive hormones on the torpor patterns of the marsupial Sminthopsis macroura: bet-hedging in an unpredictable environment.
Topics: Adaptation, Physiological; Animals; Basal Metabolism; Body Temperature; Body Temperature Regulation; Body Weight; Circadian Rhythm; Estrogens; Female; Flutamide; Hormone Antagonists; Male; Marsupialia; Mifepristone; Photoperiod; Progesterone; Reproduction; Tamoxifen; Testosterone | 2012 |
Phenotypic and metabolic aspects of prostatic epithelial cells in aged gerbils after antisteroidal therapy: turnover in the state of chromatin condensation and androgen-independent cell replacement.
Topics: Aging; Androgen Antagonists; Androgens; Animals; Cell Proliferation; Chromatin Assembly and Disassembly; Epithelial Cells; Estrogen Antagonists; Flutamide; Gerbillinae; Male; Phenotype; Prostate; Tamoxifen | 2014 |
Expression of sex hormone receptors in juvenile angiofibromas and antiproliferative effects of receptor modulators.
Topics: Adolescent; Angiofibroma; Antineoplastic Agents, Hormonal; Cell Proliferation; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Nasal Mucosa; Nose Neoplasms; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Sampling Studies; Sensitivity and Specificity; Tamoxifen; Tumor Cells, Cultured; Young Adult | 2014 |
Relationship between 22-kHz calls and testosterone in male rats.
Topics: Androgen Antagonists; Animal Communication; Animals; Cholesterol; Data Interpretation, Statistical; Estrogen Antagonists; Flutamide; Male; Orchiectomy; Physical Stimulation; Rats; Rats, Wistar; Stress, Psychological; Tamoxifen; Testosterone; Vocalization, Animal | 2014 |
Evaluation of the removal of antiestrogens and antiandrogens via ozone and granular activated carbon using bioassay and fluorescent spectroscopy.
Topics: Adsorption; Androgen Antagonists; Biological Assay; Charcoal; Coloring Agents; Endocrine Disruptors; Estrogen Receptor Modulators; Flutamide; Ozone; Spectrum Analysis; Tamoxifen; Wastewater; Water Purification | 2016 |
Neuroprotective effects of testosterone metabolites and dependency on receptor action on the morphology of somatic motoneurons following the death of neighboring motoneurons.
Topics: Androgen Antagonists; Animals; Cell Death; Cholera Toxin; Dendrites; Dihydrotestosterone; Flutamide; Horseradish Peroxidase; Male; Motor Neurons; Muscle, Skeletal; Nerve Net; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Tamoxifen; Testosterone | 2017 |
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Humans; Imipramine; Inflammation; Ketoconazole; Liver; Methyltestosterone; Oxidative Stress; Rats; Risk Assessment; Sulindac; Tamoxifen; Toxicogenetics | 2017 |
Are cytostatic drugs in surface waters a potential threat?
Topics: Child; Chlorambucil; Cyclophosphamide; Cyproterone; Cytostatic Agents; Drinking Water; Environmental Monitoring; Etoposide; Flutamide; Humans; Mycophenolic Acid; Pharmaceutical Preparations; Rivers; Tamoxifen; Water Pollutants, Chemical | 2022 |