Compounds > flutamide

flutamide and methoxychlor

flutamide has been researched along with methoxychlor in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babaï, D; Gaido, KW; Gould, JC; Leonard, LS; Lovell, S; McDonnell, DP; Portier, CJ1
Gaido, KW; Maness, SC; McDonnell, DP1
Gaido, KW; Safe, S; Waters, KM1
Derk, RC; Murono, EP1
Akgul, Y; Derk, RC; Meighan, T; Murono, EP; Rao, KM1
Cao, S; Lou, QQ; Qin, ZF; Wei, WJ; Xu, W; Zhang, YF; Zhao, YX1
Ciereszko, RE; Czaja, E; Grzesiak, M; Knapczyk-Stwora, K; Koziorowski, M; Slomczynska, M1

Trials

1 trial(s) available for flutamide and methoxychlor

ArticleYear
The impact of sex steroid agonists and antagonists on folliculogenesis in the neonatal porcine ovary via cell proliferation and apoptosis.
    Theriogenology, 2018, Volume: 113

    Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Estradiol; Estrogen Receptor Antagonists; Female; Flutamide; Fulvestrant; Granulosa Cells; Insecticides; Methoxychlor; Ovarian Follicle; Phenols; Swine; Testosterone Propionate

2018

Other Studies

6 other study(ies) available for flutamide and methoxychlor

ArticleYear
Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay.
    Toxicology and applied pharmacology, 1997, Volume: 143, Issue:1

    Topics: DDT; Dose-Response Relationship, Drug; Endocrine Glands; Environmental Pollutants; Flutamide; Hormones; Humans; In Vitro Techniques; Insecticides; Methoxychlor; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Reproducibility of Results; Saccharomyces cerevisiae; Sensitivity and Specificity; Transcription, Genetic

1997
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
    Toxicology and applied pharmacology, 1998, Volume: 151, Issue:1

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Antineoplastic Agents, Hormonal; Carcinoma, Hepatocellular; DDT; Dihydrotestosterone; Estradiol; Flutamide; Humans; Insecticides; Isomerism; Methoxychlor; Progesterone; Receptors, Androgen; Testosterone; Transcription, Genetic; Tumor Cells, Cultured

1998
Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 63, Issue:1

    Topics: Animals; DNA Primers; Drug Combinations; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Flutamide; Gene Expression Regulation; Genitalia, Female; Methoxychlor; Mice; Mice, Inbred C57BL; Ovary; Phenols; Receptors, Androgen; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uterus

2001
The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats.
    Reproductive toxicology (Elmsford, N.Y.), 2004, Volume: 19, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Dose-Response Relationship, Drug; Drug Combinations; Estrogen Antagonists; Flutamide; Insecticides; Leydig Cells; Male; Methoxychlor; Oxazoles; Phenols; Rats; Rats, Sprague-Dawley; Testosterone

2004
The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.
    Reproductive toxicology (Elmsford, N.Y.), 2008, Volume: 25, Issue:1

    Topics: Androgen Antagonists; Animals; Benzhydryl Compounds; Catalytic Domain; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Fulvestrant; Gene Expression Regulation, Enzymologic; Gonadotropins, Equine; Methoxychlor; Ovary; Oxazoles; Phenols; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger

2008
Environmental (anti-)androgenic chemicals affect germinal vesicle breakdown (GVBD) of Xenopus laevis oocytes in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:3

    Topics: Androgen Antagonists; Androgens; Animals; Endocrine Disruptors; Flutamide; Methoxychlor; Nandrolone; Oocytes; Oxazoles; Receptors, Androgen; Testosterone; Trenbolone Acetate; Xenopus laevis

2014