flutamide and medroxyprogesterone acetate

flutamide has been researched along with medroxyprogesterone acetate in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's7 (43.75)18.2507
2000's2 (12.50)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cusan, L; Labrie, C; Labrie, F; Lapointe, S; Plante, M1
Labrie, F; Lapointe, S; Plante, M1
Begin, DJ; Labrie, F; Luthy, IA1
Burger, CW; Greggi, S; Kenemans, P; van der Vange, N; Vermorken, JB1
Charreau, EH; Dran, G; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, F; Pasqualini, CD1
Couture, P; Labrie, F; Simard, J; Thériault, C1
Aichberger, A; Krebs, D; Werner, A1
Denis, L1
Fournier, M; Labrie, C; Labrie, F; Li, S; Martel, C; Pelletier, G; Picard, S; Sourla, A; Stojanovic, M1
Charreau, E; Lamb, C; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, MF; Pazos, P; Vanzulli, S1
Aso, T; Harada, T; Ishikawa, T; Kubota, T1

Trials

1 trial(s) available for flutamide and medroxyprogesterone acetate

ArticleYear
European Organization for Research and Treatment of Cancer (EORTC) prostate cancer trials, 1976-1996.
    Urology, 1998, Volume: 51, Issue:5A Suppl

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Castration; Cyproterone Acetate; Diethylstilbestrol; Doxorubicin; Epirubicin; Estramustine; Flutamide; Humans; Imidazoles; Male; Medroxyprogesterone Acetate; Methotrexate; Mitomycin; Neoplasms, Hormone-Dependent; Procarbazine; Prostatic Neoplasms; Vindesine

1998

Other Studies

15 other study(ies) available for flutamide and medroxyprogesterone acetate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
    Journal of steroid biochemistry, 1987, Volume: 28, Issue:4

    Topics: Adrenal Glands; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Organ Size; Ornithine Decarboxylase; Progesterone Congeners; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Spironolactone

1987
Stimulatory effect of synthetic progestins currently used for the treatment of prostate cancer on growth of the androgen-sensitive Shionogi tumor in mice.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:1

    Topics: Androgens; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Female; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Mice; Progesterone Congeners; Prostatic Neoplasms

1988
Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:5

    Topics: Androgens; Animals; Cell Division; Chlormadinone Acetate; Dihydrotestosterone; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Mice; Progestins; Spironolactone; Tumor Cells, Cultured

1988
Experience with hormonal therapy in advanced epithelial ovarian cancer.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Antineoplastic Agents, Hormonal; Carcinoma; Estrogen Antagonists; Female; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteolytic Agents; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Middle Aged; Ovarian Neoplasms; Progesterone Congeners; Remission Induction; Survival Rate; Tamoxifen; Triptorelin Pamoate

1995
Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma.
    Breast cancer research and treatment, 1995, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Androgen Antagonists; Animals; Blood Physiological Phenomena; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured

1995
Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells.
    Endocrinology, 1993, Volume: 132, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Flutamide; Humans; Kinetics; Medroxyprogesterone Acetate; Receptors, Androgen; Tumor Cells, Cultured

1993
[Does interferon-alpha enhance the effect of tamoxifen-medroxyprogesterone acetate and hydroxyflutamide on in vitro tumor cells?].
    Zentralblatt fur Gynakologie, 1996, Volume: 118, Issue:11

    Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Female; Flutamide; Humans; Interferon-alpha; Medroxyprogesterone Acetate; Ovarian Neoplasms; Tamoxifen; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat.
    The Journal of endocrinology, 1998, Volume: 157, Issue:3

    Topics: Androgen Antagonists; Animals; Benzopyrans; Bone Density; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Femur; Flutamide; Medroxyprogesterone Acetate; Ovariectomy; Progesterone Congeners; Propionates; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1998
Progesterone receptor involvement in independent tumor growth in MPA-induced murine mammary adenocarcinomas.
    The Journal of steroid biochemistry and molecular biology, 1999, Volume: 68, Issue:1-2

    Topics: Adenocarcinoma; Androgens; Animals; Binding Sites; Estradiol; Female; Flutamide; Glucocorticoids; Gonanes; Hormone Antagonists; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Neoplasms, Hormone-Dependent; Oligonucleotides, Antisense; Ovariectomy; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tumor Cells, Cultured

1999
Testosterone inhibits matrix metalloproteinase-1 production in human endometrial stromal cells in vitro.
    Reproduction (Cambridge, England), 2007, Volume: 133, Issue:6

    Topics: Adult; Androgen Antagonists; Blotting, Western; Cells, Cultured; Depression, Chemical; Endometrium; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Flutamide; Humans; Matrix Metalloproteinase 1; Medroxyprogesterone Acetate; Progesterone; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Stromal Cells; Testosterone

2007