flutamide and ketoconazole

flutamide has been researched along with ketoconazole in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (9.09)	18.7374
1990's	7 (15.91)	18.2507
2000's	12 (27.27)	29.6817
2010's	20 (45.45)	24.3611
2020's	1 (2.27)	2.80

Authors

Authors	Studies
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK	1
Brodie, AM; Chopra, P; Farquhar, R; Gediya, LK; Guo, Z; Handratta, VD; Kataria, R; Newman, D; Njar, VC; Qiu, Y; Vasaitis, TS	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Huben, RP	1
Bélanger, A; Caron, S; Labrie, F; Lacoste, D	1
Fair, WR; Sogani, PC	1
Belanger, A; Caron, S; Labrie, F; Lacoste, D; St-Arnaud, R	1
Boublil, JL; Cavaglione, G; Kather, R; Namer, M	1
Barrie, SE; Dowsett, M; Goddard, PM; Haynes, BP; Jarman, M; Potter, GA	1
DeAngelis, LM; Mencel, PJ; Motzer, RJ	1
Shaw, JC	1
Apodaca, D; Baron, AD; Fippin, L; Small, EJ	1
Baron, A; Bok, R; Small, EJ	1
Bagnoli, A; Colombo, FM; Flamigni, C; Macrelli, S; Marescalchi, O; Paradisi, R; Ravaioli, B; Venturoli, S	1
Amornpichetkul, K; Chakrapee-Sirisuk, S; Sangruchi, T; Sinlarat, P; Srimuninnimit, V; Visudhiphan, S	1
Culkin, DJ; Zimmerman, RA	1
Ahn, B; Baek, IJ; Choo, YK; Hong, JT; Jin, Y; Kim, MR; Lee, BJ; Lee, SR; Nam, SY; Yon, JM; Yun, YW	1
Aguilera Tubet, C; Ballestero Diego, R; Roca Edreira, A; Villanueva Peña, A; Zubillaga Guerrero, S	1
Bláha, L; Haeba, MH; Hilscherová, K; Mazurová, E	1
Panter, GH; Thorpe, KL; Weltje, L; Wheeler, JR	1
Ioannides, D; Lazaridou, E	1
Ailawadi, G; Davis, JP; Lu, G; Meher, A; Pope, NH; Salmon, M; Su, G; Upchurch, GR	1
Honda, H; Ito, Y; Kawamoto, T; Morita, O	1
Aaboe, K; Albrethsen, J; Andersson, AM; Brenøe, PT; Dreisler, E; Frederiksen, H; Greenald, D; Juul Hare, K; Juul, A; Jørgensen, A; Langhoff Thuesen, L; Lundgaard Riis, M; Matilionyte, G; Melau, C; Mitchell, RT; Nielsen, JE; Rajpert-De Meyts, E	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Alvarez-Manrique, B; Bratoeff, E; Cabeza, M; Cortés-Benítez, F; Ramírez-Apan, MT	1

Reviews

7 review(s) available for flutamide and ketoconazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Treatment of advanced prostatic cancer. The Urologic clinics of North America, 1987, Volume: 14, Issue:2 Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors	1987
Antiandrogen therapy in dermatology. International journal of dermatology, 1996, Volume: 35, Issue:11 Topics: Adrenal Cortex Hormones; Androgen Antagonists; Cimetidine; Contraceptives, Oral; Cyproterone Acetate; Finasteride; Flutamide; Humans; Ketoconazole; Skin Diseases; Spironolactone	1996
Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2001, Volume: 84, Issue:10 Topics: Antifungal Agents; Antineoplastic Agents, Hormonal; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Flutamide; Humans; Ketoconazole; Male; Middle Aged; Prostatic Neoplasms	2001
Clinical strategies in the management of biochemical recurrence after radical prostatectomy. Clinical prostate cancer, 2003, Volume: 2, Issue:3 Topics: Androgen Antagonists; Antifungal Agents; Cytochrome P-450 Enzyme System; Disease-Free Survival; Flutamide; Humans; Ketoconazole; Male; Neoplasm Recurrence, Local; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Risk Factors	2003
Test concentration setting for fish in vivo endocrine screening assays. Chemosphere, 2013, Volume: 92, Issue:9 Topics: Androstenedione; Animals; Endocrine Disruptors; Ethylene Glycols; Fishes; Flutamide; Imidazoles; Ketoconazole; Maximum Tolerated Dose; Octanols; Phenols; Potassium Permanganate; Sodium Dodecyl Sulfate	2013
Female pattern hair loss. Current problems in dermatology, 2015, Volume: 47 Topics: 5-alpha Reductase Inhibitors; Administration, Cutaneous; Alopecia; Androgen Antagonists; Androgen Receptor Antagonists; Antifungal Agents; Cyproterone Acetate; Dutasteride; Female; Finasteride; Flutamide; Hair; Humans; Ketoconazole; Minoxidil; Postmenopause; Spironolactone; Vasodilator Agents	2015

Trials

5 trial(s) available for flutamide and ketoconazole

Article	Year
Hormone therapy of prostatic bone metastases. Advances in experimental medicine and biology, 1992, Volume: 324 Topics: Actuarial Analysis; Androgen Antagonists; Bone Neoplasms; Combined Modality Therapy; Diethylstilbestrol; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Goserelin; Humans; Ketoconazole; Leuprolide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Remission Induction; Spironolactone; Survival Rate	1992
Treatment of advanced prostatic cancer. The Urologic clinics of North America, 1987, Volume: 14, Issue:2 Topics: Adrenalectomy; Aminoglutethimide; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cyproterone; Cyproterone Acetate; Estrogens; Flutamide; Glucocorticoids; Humans; Ketoconazole; Male; Megestrol; Megestrol Acetate; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Spironolactone; Time Factors	1987
Ketoconazole retains activity in advanced prostate cancer patients with progression despite flutamide withdrawal. The Journal of urology, 1997, Volume: 157, Issue:4 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Disease Progression; Flutamide; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms	1997
Simultaneous antiandrogen withdrawal and treatment with ketoconazole and hydrocortisone in patients with advanced prostate carcinoma. Cancer, 1997, Nov-01, Volume: 80, Issue:9 Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Androgen Antagonists; Cohort Studies; Flutamide; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Substance Withdrawal Syndrome; Treatment Outcome	1997
A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole, and cyproterone acetate-estrogen regimens in the treatment of hirsutism. The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:4 Topics: Adult; Cyproterone Acetate; Ethinyl Estradiol; Female; Finasteride; Flutamide; Hirsutism; Hormones; Humans; Ketoconazole; Prospective Studies	1999

Other Studies

33 other study(ies) available for flutamide and ketoconazole

Article	Year
Identification and prediction of promiscuous aggregating inhibitors among known drugs. Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21 Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship	2003
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8 Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstadienes; Animals; Antineoplastic Agents; Azoles; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Humans; Isoenzymes; Male; Mice; Mice, SCID; Mutation; Prostatic Neoplasms; Pyrazines; Radioligand Assay; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Tissue Distribution; Transcription, Genetic; Transcriptional Activation; Xenograft Model Antitumor Assays	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Effect of 3-week treatment with [D-Trp6, des-Gly-NH10(2)]LHRH ethylamide, aminoglutethimide, ketoconazole or flutamide alone or in combination on testicular, serum, adrenal and prostatic steroid levels in the dog. Journal of steroid biochemistry, 1989, Volume: 33, Issue:2 Topics: Adrenal Glands; Aminoglutethimide; Androgens; Animals; Dogs; Flutamide; Gonadotropin-Releasing Hormone; Ketoconazole; Male; Prostate; Testis; Triptorelin Pamoate	1989
The rise in testicular androgens during the first days of treatment with an LHRH agonist in the dog can be blocked by aminoglutethimide or ketoconazole. Journal of steroid biochemistry, 1988, Volume: 31, Issue:6 Topics: Aldehyde-Lyases; Aminoglutethimide; Androgens; Animals; Cytochrome P-450 Enzyme Inhibitors; Dogs; Estradiol; Flutamide; Gonadotropin-Releasing Hormone; Ketoconazole; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Testis; Testosterone; Triptorelin Pamoate	1988
[Cancer of the prostate: new hormone therapies]. Bulletin du cancer, 1986, Volume: 73, Issue:1 Topics: Androgen Antagonists; Cyproterone; Flutamide; Humans; Ketoconazole; Male; Medroxyprogesterone; Megestrol; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Tamoxifen	1986
Pharmacology of novel steroidal inhibitors of cytochrome P450(17) alpha (17 alpha-hydroxylase/C17-20 lyase). The Journal of steroid biochemistry and molecular biology, 1994, Volume: 50, Issue:5-6 Topics: Abiraterone Acetate; Adrenal Glands; Aldehyde-Lyases; Androgens; Androstadienes; Androstenes; Androstenols; Animals; Cytochrome P-450 Enzyme Inhibitors; Flutamide; Guinea Pigs; Ketoconazole; Kidney; Luteinizing Hormone; Male; Mice; Orchiectomy; Organ Size; Prostate; Seminal Vesicles; Steroid 17-alpha-Hydroxylase; Testis; Testosterone	1994
Hormonal ablation as effective therapy for carcinomatous meningitis from prostatic carcinoma. Cancer, 1994, Apr-01, Volume: 73, Issue:7 Topics: Adenocarcinoma; Aged; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Flutamide; Follow-Up Studies; Humans; Ketoconazole; Leuprolide; Male; Meningeal Neoplasms; Meningitis; Prostatic Neoplasms	1994
Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes. Journal of veterinary science, 2007, Volume: 8, Issue:3 Topics: Androgen Antagonists; Animals; Diethylhexyl Phthalate; Diethylstilbestrol; Endocrine Disruptors; Estrogens, Non-Steroidal; Flutamide; Glutathione Peroxidase; Histocytochemistry; Ketoconazole; Male; Phenols; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatogenesis; Testis; Testosterone	2007
[Mediastinal lymph nodes during the course of a metastatic prostate cancer]. Actas urologicas espanolas, 2007, Volume: 31, Issue:6 Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyproterone; Diphosphonates; Estramustine; Fatal Outcome; Flutamide; Humans; Imidazoles; Ketoconazole; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinum; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Radionuclide Imaging; Skin Neoplasms; Triptorelin Pamoate; Zoledronic Acid	2007
Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna. Environmental science and pollution research international, 2008, Volume: 15, Issue:3 Topics: Animals; Animals, Newborn; Daphnia; Dicofol; Endocrine Disruptors; Female; Flutamide; Ketoconazole; Locomotion; Male; Molting; Oxazoles; Reproduction; Sex Ratio; Sexual Maturation; Water Pollutants, Chemical	2008
Pharmacologic blockade and genetic deletion of androgen receptor attenuates aortic aneurysm formation. Journal of vascular surgery, 2016, Volume: 63, Issue:6 Topics: Androgen Antagonists; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cytokines; Disease Models, Animal; Disease Progression; Flutamide; Gene Deletion; Gene Expression Regulation; Genotype; Humans; Inflammation Mediators; Ketoconazole; Male; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phenotype; Receptors, Androgen; RNA, Messenger; Time Factors	2016
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics. The Journal of toxicological sciences, 2017, Volume: 42, Issue:4 Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Humans; Imipramine; Inflammation; Ketoconazole; Liver; Methyltestosterone; Oxidative Stress; Rats; Risk Assessment; Sulindac; Tamoxifen; Toxicogenetics	2017
Identification of a window of androgen sensitivity for somatic cell function in human fetal testis cultured ex vivo. BMC medicine, 2022, 10-20, Volume: 20, Issue:1 Topics: Androgens; Flutamide; Humans; Ketoconazole; Male; Receptors, Androgen; Testicular Hormones; Testis; Testosterone	2022
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line. European journal of medicinal chemistry, 2016, Oct-04, Volume: 121 Topics: Androgens; Androstenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Humans; Leukocytes, Mononuclear; Male; Prostatic Neoplasms; Rats	2016