flutamide and estrone

flutamide has been researched along with estrone in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's3 (13.04)18.2507
2000's6 (26.09)29.6817
2010's11 (47.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Bellavance, E; Luu-The, V; Poirier, D1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Daly, JJ; Griffin, PP; Irwin, RJ; Kliman, B; MacLaughlin, RA; Prout, GR1
de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R1
Duleba, AJ; Ho Yuen, B; Kim, KS; Moon, YS1
Berman, C; Brooks, JR; Hichens, M; Primka, RL; Rasmusson, GH; Reynolds, GF1
Giannoulis, G; Hadziyannis, SJ; Manesis, EK; Vafiadou, I; Zoumboulis, P1
Couture, P; Labrie, F; Simard, J; Thériault, C1
Caruso, A; De Leo, V; Fulghesu, AM; la Marca, A; Morgante, G; Pasqui, L; Talluri, B; Torricelli, M1
Atkin, SL; Bilko, D; Newton, CJ; Pappa, S1
Chang, RJ; Malcom, PJ; Mehta, RV1
Jin, Y; Liu, ZW; Sun, HY; Tong, da Y; Wen, XQ; Wu, XY; Zhou, FJ1
Barragán Mejía, G; Bratoeff, E; Calderón Guzmán, D; Hernández García, E; Juárez Olguín, H; Osnaya Brizuela, N; Pierdant Rioja, F; Ramírez López, E; Santamaría Del Ángel, D; Trujillo Jiménez, F1
Jin, Y; Liu, Zw; Sun, Hy; Tong, da Y; Wu, Xy; Zhou, Fj1
Ciereszko, RE; Grzesiak, M; Knapczyk-Stwora, K; Slomczynska, M; Wieciech, I1
Acosta, JI; Alderete, TJ; Bimonte-Nelson, HA; Camp, BW; Demers, LM; Koebele, SV; Mennenga, SE; Mousa, AA; Tsang, CW1
Alonso-Diez, A; Caceres, S; de Andres, PJ; Illera, JC; Illera, MJ; Monsalve, B; Peña, L; Reuben, JM; Silvan, G; Woodward, WA1

Reviews

1 review(s) available for flutamide and estrone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for flutamide and estrone

ArticleYear
Treatment of hepatocellular carcinoma with combined suppression and inhibition of sex hormones: a randomized, controlled trial.
    Hepatology (Baltimore, Md.), 1995, Volume: 21, Issue:6

    Topics: Analysis of Variance; Androgens; Carcinoma, Hepatocellular; Double-Blind Method; Drug Therapy, Combination; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Liver Neoplasms; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Placebos; Probability; Survival Rate; Tamoxifen; Time Factors; Triptorelin Pamoate

1995
Hormonal and clinical effects of GnRH agonist alone, or in combination with a combined oral contraceptive or flutamide in women with severe hirsutism.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2000, Volume: 14, Issue:6

    Topics: Adult; Amenorrhea; Androgen Antagonists; Contraceptives, Oral, Combined; Cyproterone Acetate; Estradiol; Estradiol Congeners; Estrone; Ethinyl Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Luteinizing Hormone; Luteolytic Agents; Polycystic Ovary Syndrome; Progesterone Congeners; Prospective Studies; Triptorelin Pamoate

2000
Alterations in luteal production of androstenedione, testosterone, and estrone, but not estradiol, during mid- and late pregnancy in pigs: effects of androgen deficiency.
    Theriogenology, 2014, Sep-15, Volume: 82, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androstenedione; Animals; Aromatase; Corpus Luteum; Estradiol; Estrone; Female; Flutamide; Gene Expression Regulation, Enzymologic; Pregnancy; Steroid 17-alpha-Hydroxylase; Swine; Testosterone

2014

Other Studies

19 other study(ies) available for flutamide and estrone

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Prostatic cancer and SCH-13521: II. Histological alterations and the pituitary gonadal axis.
    The Journal of urology, 1975, Volume: 113, Issue:6

    Topics: Aged; Anilides; Biopsy, Needle; Cerebrovascular Disorders; Estradiol; Estrone; Flutamide; Follicle Stimulating Hormone; Gynecomastia; Humans; Luteinizing Hormone; Male; Middle Aged; Prostatic Neoplasms; Sexual Behavior; Spermatozoa; Testosterone; Thromboembolism; Thrombosis; Vomiting

1975
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured

1991
Inhibition of 20 alpha-hydroxysteroid dehydrogenase activity by follicle-stimulating hormone and androgens in cultured rat granulosa cells: a search for the mechanism of action.
    Biology of reproduction, 1985, Volume: 33, Issue:2

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Dihydrotestosterone; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; Rats; Rats, Inbred Strains; Testosterone

1985
Biological activities of a new steroidal inhibitor of delta 4-5 alpha-reductase.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:1

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Body Weight; Dihydrotestosterone; Dose-Response Relationship, Drug; Estrone; Female; Feminization; Fertility; Flutamide; Male; Organ Size; Ovary; Oxidoreductases; Prolactin; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles; Steroids, Heterocyclic; Uterus

1982
Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells.
    Endocrinology, 1993, Volume: 132, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Flutamide; Humans; Kinetics; Medroxyprogesterone Acetate; Receptors, Androgen; Tumor Cells, Cultured

1993
Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells.
    The Journal of endocrinology, 2001, Volume: 169, Issue:2

    Topics: Adenosine Triphosphate; Cell Death; Dexamethasone; Estradiol; Estrogen Receptor Modulators; Estrone; Flow Cytometry; Flutamide; Fulvestrant; Glucocorticoids; Glyceraldehyde-3-Phosphate Dehydrogenases; Gonanes; Humans; Hydrogen Peroxide; Microscopy, Fluorescence; Mifepristone; Pituitary Neoplasms; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, Cell Surface; Transfection; Tumor Cells, Cultured

2001
The effect of androgen blockade on granulosa cell estradiol production after follicle-stimulating hormone stimulation in women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Adult; Androgen Antagonists; Androstenedione; Area Under Curve; Cohort Studies; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Prospective Studies; Recombinant Proteins; Sex Hormone-Binding Globulin; Testosterone

2006
Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.
    Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction

2010
Effect of flutamide and two novel synthetic steroids on GABA, glutamine and some oxidative stress markers in rat brain and prostate.
    Andrologia, 2011, Volume: 43, Issue:4

    Topics: Animals; Brain; Diazepam; Estrone; Flutamide; gamma-Aminobutyric Acid; Glutamine; Glutathione; Lipid Peroxidation; Male; Oxidative Stress; Progesterone; Prostate; Rats; Rats, Wistar; Serotonin; Sodium-Potassium-Exchanging ATPase; Testosterone

2011
Expression changes and regulation of AR and IGF-1 in PC3 prostate cancer cells treated with sexual hormones and flutamide.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2012, Volume: 33, Issue:6

    Topics: Androgen Antagonists; Androgens; Blotting, Western; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured

2012
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition Disorders; Estrone; Female; Flutamide; Maze Learning; Menopause; Nitriles; Ovariectomy; Rats, Inbred F344; Receptors, Androgen; Triazoles; Uterus

2015
In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Dog Diseases; Dogs; Estradiol; Estrone; Female; Flutamide; Gonadal Steroid Hormones; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnenolone; Progesterone; Testosterone

2018