flutamide has been researched along with dihydrotestosterone in 315 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 69 (21.90) | 18.7374 |
| 1990's | 96 (30.48) | 18.2507 |
| 2000's | 87 (27.62) | 29.6817 |
| 2010's | 56 (17.78) | 24.3611 |
| 2020's | 7 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Ackerman, JH; Bell, MR; Christiansen, RG; D'Ambra, TE; Herrmann, JL; Kullnig, RK; Mallamo, JP; Opalka, CJ; Snyder, BW; Winneker, RC | 1 |
| Bellavance, E; Luu-The, V; Poirier, D | 1 |
| Badalassi, F; Bertozzi, F; Bradley, SR; Fejzic, A; Gardell, LR; Lewinsky, R; Lund, BW; Olsson, R; Pawlas, J; Piu, F; Schlienger, N; Tabatabaei, A; Thygesen, MB | 1 |
| Daly, JJ; Griffin, PP; Kliman, B; Maclaughlin, RA; Prout, GR | 1 |
| Chisholm, GD; Ghanadian, R; Smith, CB; Williams, G | 1 |
| Bruchovsky, N; Callaway, T; Comeau, T; Lakey, WH; Lieskovsky, G; Rennie, P; Shnitka, T; Wilkin, P | 1 |
| Bonne, C; Bouton, MM; Labrie, F; Lagace, L; Raynaud, JP | 1 |
| Takayasu, S | 2 |
| Neri, R; Peets, E; Watnick, A | 1 |
| Katzenellenbogen, BS; Schmidt, WN | 1 |
| Liao, S; Tymoczko, JL | 1 |
| Sandberg, AA | 1 |
| Cuthbertson, TL; Li, JJ; Li, SA | 1 |
| Harman, SM; Louvet, JP; Ross, GT; Schrieber, JR | 1 |
| Connors, K; Geller, J; Hoffman, RM; Sionit, LR | 1 |
| Huber, GK; Kirschenbaum, A; Levine, AC; Ren, M | 1 |
| Chalmers, D; Kirk, D; Leake, RE; Lloyd, SN | 1 |
| Beato, M; Bock, K; Filmer, A; Hackenberg, R; Hawighorst, T; Schulz, KD; Slater, EP | 1 |
| Bernasconi, D; Cassulo, S; Fazzuoli, L; Giordano, G; Marugo, M; Miglietta, L; Ravera, F | 1 |
| Bélanger, A; Bélanger, B; Boudou, P; Caron, S; Fiet, J | 1 |
| van der Schoot, P | 1 |
| Imperato-McGinley, J; Sanchez, RS; Spencer, JR; Torrado, T; Vaughan, ED | 1 |
| Imai, K; Nakata, S; Nakazawa, Y; Takahashi, O; Watanabe, K; Yamanaka, H | 1 |
| de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R | 1 |
| Couêt, J; Labrie, C; Labrie, F; Li, S; Martel, C; Trudel, C | 1 |
| Brand, T; Slob, AK | 1 |
| Korpacheva, T; Reznikov, A | 1 |
| Brann, DW; Mahesh, VB; Putnam, CD | 1 |
| Torday, JS | 1 |
| Arbusow, V; Bojar, H; Fittler, F; Klobeck, HG; Schulz, P; Wolf, D | 1 |
| Couture, M; Couture, N; Dupont, A; Labrie, F; Rousseau, L | 1 |
| Callard, GV; Schlinger, BA | 1 |
| Olea, N; Sakabe, K; Sonnenschein, C; Soto, AM | 1 |
| Dauvois, S; Haagensen, DE; Labrie, F; Lévesque, C; Mérand, Y; Simard, J | 1 |
| Kitamura, Y; Li, W; Matsumoto, K; Takada, T; Taniguchi, H; Terada, N; Terakawa, N; Yamamoto, R | 1 |
| Cusan, L; Labrie, C; Labrie, F; Lapointe, S; Plante, M | 1 |
| Concolino, G; Conti, C; Di Silverio, F; Lubrano, C; Petrangeli, E; Sciarra, F; Toscano, V | 1 |
| Begin, DJ; Labrie, F; Luthy, IA | 1 |
| Erulkar, SD; Wetzel, DM | 1 |
| Erskine, MS | 2 |
| Dauvois, S; Labrie, F; Li, SM; Martel, C | 1 |
| Baylink, DJ; Farley, JR; Kasperk, CH; Linkhart, TA; Turner, RT; Wergedal, JE | 1 |
| Belis, JA; Durham, JP | 1 |
| Chalbos, D; Chambon, M; Rochefort, H; Vial, HJ | 1 |
| Hib, J; Magariños, GA | 1 |
| Hammond, JM; Spicer, LJ | 1 |
| Dias, JA; Swift, TA | 1 |
| Labrie, F; Marchetti, B; Plante, M; Poulin, R | 1 |
| Hammer, RP | 1 |
| Fukata, J; Martin, JB | 1 |
| Cunningham, GR; Kong, AY; Shao, TC | 1 |
| el Etreby, MF; Habenicht, UF; Louton, T; Nishino, Y; Schröder, HG | 1 |
| Bruchovsky, N; Fletcher, T; Foekens, JA; Goldenberg, SL; Lawson, D; Rennie, PS | 1 |
| Donn, F; Tamm, J; Volkwein, U | 1 |
| Ballerini, P; Fariselli, G; Recchione, C; Secreto, G; Zambetti, M | 1 |
| Duleba, AJ; Ho Yuen, B; Kim, KS; Moon, YS | 1 |
| Canellos, GP | 1 |
| Leung, A; Wang, C | 1 |
| Brodie, AM; Hammond, JO; Wing, LY | 1 |
| Baker, D; Labrie, F; Poulin, R | 1 |
| Bélanger, A; Cusan, L; Dupont, A; Emond, J; Giguère, M; Labrie, C; Labrie, F; Lacourcière, Y; Monfette, G | 1 |
| Bélanger, A; Dupont, A; Emond, J; Giguère, M; Labrie, F; Lacourcière, Y; Monfette, G; St-Arnaud, R | 1 |
| Tokarz, RR | 1 |
| Chalbos, D; Haagensen, D; Parish, T; Rochefort, H | 1 |
| Mauvais-Jarvis, P; Mowszowicz, I; Portois, MC; Santen, RJ | 1 |
| Benz, C; Hollander, C; Miller, B | 1 |
| Labrie, F; Luthy, I | 1 |
| Geller, J | 1 |
| Hillier, SG; Purohit, A; Reichert, LE | 1 |
| Labrie, F; Poyet, P | 1 |
| Albert, J; Geller, J; Geller, S; Loza, D; Nachtsheim, DA | 1 |
| Hano, R; Knuth, UA; Nieschlag, E | 1 |
| Belanger, A; Le Goff, JM | 1 |
| Lax, ER; Schriefers, H | 1 |
| Assimos, D; Grayhack, JT; Lee, C; Smith, C | 1 |
| Baumann, P; Lax, ER; Schriefers, H | 1 |
| Clemens, LG; Dohanich, GP | 1 |
| Resko, JA; Roselli, CE | 1 |
| Ahmed, T; Benedetto, P; Herr, HW; Pertschuk, L; Scher, HI; Sogani, PC; Watson, RC; Whitmore, WF; Yagoda, A | 1 |
| Azzolin, GC; Saiduddin, S | 1 |
| Nielsen, HC; Torday, JS; Zinman, HM | 1 |
| Ip, MM; Kim, U; Milholland, RJ; Rosen, F | 1 |
| Kalra, PS; Kalra, SP | 1 |
| Berman, C; Brooks, JR; Hichens, M; Primka, RL; Rasmusson, GH; Reynolds, GF | 1 |
| Searcy, WA; Wingfield, JC | 1 |
| Krey, LC; McEwen, BS; Robbins, R | 1 |
| Arth, GE; Baptista, EM; Berman, C; Brooks, JR; Ham, EA; Hichens, M; Johnston, DB; Primka, RL; Rasmusson, GH; Reynolds, GF; Schmitt, SM | 1 |
| King, RJ; Yates, J | 1 |
| Besa, EC; Bullock, LP | 1 |
| Davidson, JM; Gray, GD; Smith, ER | 1 |
| Baum, MJ; Erskine, MS; Marcus, JI | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gatto, V; Leonardi, L | 1 |
| Baird, A; Connors, KM; Geller, J; Hoffman, RM; Kohls, M; Sionit, LR | 1 |
| Calabrò, M; Carruba, G; Castagnetta, LA; Farruggio, R; Miceli, MD; Oliveri, G; Pfeffer, U; Sorci, CM | 1 |
| Bravo, AI; Calandra, RS; Capurro, MI; Donaldson, M; Luthy, IA; Mordoh, J; Morvillo, V; Quintans, C | 1 |
| Carruba, G; Castagnetta, LA; Comito, L; D'Amico, D; Farruggio, R; Miceli, D; Montesanti, A; Polito, L | 1 |
| Charreau, EH; Dran, G; Lanari, C; Luthy, IA; Molinolo, AA; Montecchia, F; Pasqualini, CD | 1 |
| Kelce, WR; Sar, M; Wilson, EM; Wong, C | 1 |
| Ball, RA; Leder, P; Ornitz, DM; Richie, JP; Tutrone, RF | 1 |
| Adler, GH; Brown, TJ; Hochberg, RB; MacLusky, NJ; Sharma, M | 1 |
| Aragno, M; Boccuzzi, G; Brignardello, E; Danni, O; Di Monaco, M; Tamagno, E | 1 |
| Gorczynska, E; Handelsman, DJ | 1 |
| Bentel, JM; Birrell, SN; Hickey, TE; Horsfall, DJ; Ricciardelli, C; Tilley, WD; Weger, MA | 1 |
| Bentvelsen, FM; George, FW; McPhaul, MJ; Wilson, JD | 1 |
| Biordi, L; Bologna, M; Festuccia, C; Muzi, P; Vicentini, C | 1 |
| Kelley, DB; Robertson, JC; Watson, JT | 1 |
| Boccuzzi, G; Brignardello, E; Di Monaco, M; Gallo, M; Gatto, V; Leonardi, L; Pizzini, A | 1 |
| Hagen, R; Hoppe, F; Romalo, G; Schwab, B; Schweikert, HU | 1 |
| Dell'Acqua, G; Fattorossi, A; Iacopino, F; Marchetti, P; Pavone-Macaluso, M; Sica, G; van der Kwast, TH | 1 |
| Govindan, MV; Koutsilieris, M; Pagé, N; Warriar, N | 2 |
| Lee, SZ; Masai, M; Sato, N; Shimazaki, J; Suzuki, H; Watabe, Y | 1 |
| Labrie, F | 1 |
| Husmann, DA; Lephart, ED | 1 |
| Hatayama, H; Higuchi, T; Imai, K; Inoue, T; Kanzaki, H; Kariya, M; Mori, T; Narukawa, S | 1 |
| Fanger, GR; Henderson, LP; Maue, RA; Tabb, JS; Wilson, EM | 1 |
| Cantabrana, B; Gutierrez, M; Hidalgo, A; Sánchez Aparicio, JA | 1 |
| Jo, T; Saji, F; Tanizawa, O; Terada, N | 1 |
| Couture, P; Labrie, F; Simard, J; Thériault, C | 1 |
| Brentani, MM; Escaleira, MT; Sonohara, S | 1 |
| Denis, L | 1 |
| Bélanger, A; Couet, J; Labrie, C; Labrie, F; Martel, C; Trudel, C | 1 |
| Brentani, MM; Liberato, MH; Sonohara, S | 1 |
| Akaza, H; Aso, Y; Fuse, H; Hosaka, M; Kawai, T; Koiso, K; Kumamoto, Y; Origasa, S; Shimazaki, J; Yamanaka, H | 1 |
| Chambers, TJ; Gallagher, AC; Tobias, JH | 1 |
| Chang, C; Yeh, S | 1 |
| Crumrine, D; Elias, PM; Feingold, KR; Hanley, K; Jiang, Y; Komüves, L; Rassner, U; Vansomphone, D; Williams, ML | 1 |
| Bentvelsen, FM; Boersma, WJ; Brinkmann, AO; Nijman, JM; Schröder, FH; van der Kwast, TH; van der Linden, JE; van der Schoot, P | 1 |
| Beck, S; Hackenberg, R; Hannig, K; Schmidt-Rhode, P; Scholz, A; Schulz, KD | 1 |
| Batchelor, KW; Grant, ES; Habib, FK | 1 |
| di Salle, E; Giudici, D; Zaccheo, T | 2 |
| Jimenez, J; Luizzi, MF; Sonnenschein, C; Soto, AM; Szelei, J | 1 |
| Chen, Y; Elbrecht, A; Rutledge, SJ; Schmidt, A; Toney, JH | 1 |
| Baamonde, A; Gutiérrez, M; Hidalgo, A; Menéndez, L; Ruiz-Gayo, M | 1 |
| Galosy, S; Gudmundsson, GO; Newcomer, B; Sridaran, R; Talamantes, F; Thordarson, G | 1 |
| Harris, SA; Hicok, KC; Hofbauer, LC; Khosla, S; Robinson, JA; Schroeder, MJ | 1 |
| Barañao, JL; Bley, MA; Saragüeta, PE | 1 |
| Boschelli, F; Caplan, AJ; Fang, Y; Fliss, AE | 1 |
| Bofill, N; Hubank, M; Melià, MJ; Meseguer, A | 1 |
| Labrie, C; Labrie, F; Martel, C; Sourla, A | 1 |
| Belsham, DD; Brown, TJ; Duc, VL; Evangelou, A; Roy, D | 1 |
| Danielpour, D; Lucia, MS; Roberts, AB; Sporn, MB; Stewart, LV | 1 |
| Amir-Zaltsman, Y; Jaffe, A; Knoll, E; Kohen, F; Somjen, D; Stern, N | 1 |
| Fournier, M; Labrie, C; Labrie, F; Li, S; Martel, C; Pelletier, G; Picard, S; Sourla, A; Stojanovic, M | 1 |
| Gaido, KW; Maness, SC; McDonnell, DP | 1 |
| Handa, RJ; Wilson, ME | 1 |
| Newman, H; Olsen, I; Parkar, M; Tabona, P | 1 |
| Hicok, KC; Hofbauer, LC; Khosla, S | 1 |
| Balk, SP; Bubley, GJ; Fenton, MA; Fertig, AM; Kolvenbag, G; Shuster, TD; Taplin, ME | 1 |
| Cavazzini, P; degli Uberti, EC; del Senno, L; Fallo, F; Rossi, R; Valentini, A; Zatelli, MC | 1 |
| Fournier, A; Labrie, C; Lapointe, J; Richard, V | 1 |
| Judd, J; Kremer, M; Oursler, MJ; Pascoe, D; Pederson, L; Riggs, BL; Spelsberg, TC | 1 |
| Bisht, D; Chakraborti, PK; Rana, S | 1 |
| Kellogg, CK; Lundin, A | 1 |
| Budman, DR; Kreis, W; Liu, XM; Wang, LG | 1 |
| Altwein, J; Boyle, P; Denis, LJ; Griffiths, K; Kirby, R; Robertson, C; Schröder, F; Turkes, A | 1 |
| Bustos-Valdes, SM; Gornstein, RA; Lapp, CA; Zamorano, P | 1 |
| Hackenberg, R; Loos, S; Schulz, KD | 1 |
| Doncarlos, LL; McAbee, MD | 1 |
| Hofbauer, LC; Khosla, S; Ten, RM | 1 |
| Fan, Z; Mendelsohn, J; Ye, D | 1 |
| Calandra, RS; Cónsole, GG; Gómez Dumm, CL; Riccillo, FL; Rulli, SB | 1 |
| Hu, S; Lu, S; Simon, NG; Wang, Y | 1 |
| Burek, MJ; Gould, TW; Ishihara, R; Lo, AC; Oppenheim, RW; Prevette, D | 1 |
| Celermajer, DS; Death, AK; Handelsman, DJ; Jessup, W; McCrohon, JA; Nakhla, S; Stanley, KK | 1 |
| Cooke, GM; Schrader, TJ | 1 |
| Brown, TJ; Evangelou, A; Jindal, SK; Letarte, M | 1 |
| Knight, PG; Silva, CC | 1 |
| Jones, GR; Lyng, FM; Rommerts, FF | 1 |
| Barlow, NJ; Foster, PM; Gaido, KW; Maness, SC; McIntyre, BS; Wallace, DG | 1 |
| Damien, E; Lanyon, LE; Price, JS | 1 |
| Bentel, JM; Buchanan, G; Greenberg, NM; Han, G; Harris, JM; Horsfall, DJ; Marshall, VR; Matusik, RJ; Moore, N; Nahm, HS; Tilley, WD; Yang, M | 1 |
| Shilling, AD; Williams, DE | 1 |
| Appa Rao, KB; Gui, Y; Lessey, BA; Lovely, LP | 1 |
| Chen, Q; Chihara, K; Kaji, H; Sugimoto, T | 1 |
| Holst, M; Ritzén, EM; Svechnikov, K | 1 |
| Fuse, H; Junicho, A; Kishi, H; Korkmaz, K; Matsuda, T; Muraguchi, A; Saatcioglu, F; Yamamoto, T | 1 |
| Isobe, N; Kaneko, H; Komai, K; Nagahori, H; Saito, K; Tomigahara, Y | 1 |
| Calandra, RS; Cónsole, GM; Gómez Dumm, CL; Jurado, SB; Rulli, SB | 1 |
| Goto, K; Morinaga, H; Nawata, H; Nomura, M; Okabe, T; Takayanagi, R; Tomura, A; Yanase, T | 1 |
| Antus, B; Heemann, U; Liu, S; Lutz, J; Song, E; Yao, Y | 1 |
| Bobseine, KL; Britt, BH; Cardon, MC; Gray, LE; Hartig, PC; Lambright, CR; Wilson, VS | 1 |
| Anderson, LA; Barnett, AH; Harte, AL; Kumar, S; McTernan, PG | 1 |
| Furutani, T; Hashimoto, T; Kato, S; Koutoku, H; Kudoh, M; Shikama, H; Shimizu, Y; Tanimoto, K; Watanabe, T | 1 |
| Bongers, G; Buttini, M; LeFevour, A; Mucke, L; Raber, J | 1 |
| Juraska, JM; Nuñez, JL; Sodhi, J | 1 |
| Bonmassar, E; Faraoni, I; Missale, C; Rizzetti, MC; Sigala, S; Spano, P; Tognazzi, N | 1 |
| Agranov, E; Hauben, E; Mizrahi, T; Schwartz, M | 1 |
| McLachlan, RI; O'Donnell, L; Ooi, GT; Pratis, K; Robertson, DM; Stanton, PG | 1 |
| Frederickson, CE; Mabjeesh, NJ; Simons, JW; Willard, MT; Zhong, H | 1 |
| Aozasa, K; Chang, C; Chang, HC; Harada, Y; Kang, HY; Miyamoto, H; Nishimura, K; Nonomura, N; Okuyama, A; Shin, M; Ting, HJ; Tokizane, T; Yeh, S | 1 |
| Chen, F; Iwamoto, Y; Langenstroer, P; See, W; Zhang, G | 1 |
| Fukabori, Y; Honma, S; Kashiwagi, B; Ono, Y; Shibata, Y; Suzuki, K; Yamanaka, H | 1 |
| Donahoe, PK; Houk, CP; Martinelle, N; Pearson, EJ; Teixeira, J | 1 |
| Dick, IM; Glendenning, P; Liu, J; Prince, RL | 1 |
| Calandra, RS; Campo, S; Rulli, SB; Zitta, K | 1 |
| Moore, IT; Walker, BG; Wingfield, JC | 1 |
| Armstrong, DT; Gilchrist, RB; Hickey, TE; Marrocco, DL; Norman, RJ | 1 |
| Ko, K; Moore, RW; Peterson, RE; Theobald, HM | 1 |
| Bélanger, A; Bélanger, MC; Julien, P; Labrie, C; Labrie, F; Leblanc, M; Tchernof, A | 1 |
| Haldy, ME; Handa, RJ; Lund, TD; Munson, DJ | 1 |
| Hurd, KS; Hutchinson, TH; Panter, GH; Sherren, A; Stanley, RD; Tyler, CR | 1 |
| Baltogiannis, D; Charalabopoulos, K; Giannakopoulos, X; Sofikitis, N | 1 |
| Lou, YR; Nazarova, N; Talonpoika, R; Tuohimaa, P | 1 |
| Ankley, GT; Cardon, M; Defoe, DL; Gray, LE; Hartig, P; Jensen, KM; Kahl, MD; Makynen, EA; Miracle, A; Wilson, V | 1 |
| Friel, PJ; Griswold, MD; Nie, R; Shima, JE; Zhou, Q | 1 |
| Jasso-Kamel, J; Montaño, LM; Navarrete, E; Perusquía, M | 1 |
| Hata, T; Hori, S; Hosoya, K; Mori, S; Nagai, Y; Ohtsuki, S; Terasaki, T; Tomi, M | 1 |
| Grantham, J; Kurahashi, H; Kusaka, M; Marunouchi, T; Nagao, S; Nishii, K; Takahashi, H | 1 |
| Heikkilä, M; Itäranta, P; Leppäluoto, J; Naillat, F; Peltoketo, H; Prunskaite, R; Vainio, S; Vuoristo, J | 1 |
| Amato, F; Armstrong, DT; Gilchrist, RB; Hickey, TE; Marrocco, DL; Norman, RJ; Ritter, LJ | 1 |
| Hareramadas, B; Rai, U | 1 |
| Graves, FC; Wallen, K | 1 |
| Benbrahim-Tallaa, L; Waalkes, MP; Webber, MM | 1 |
| Bland, KI; Chaudry, IH; Choudhry, MA; Hsieh, YC; Schwacha, MG; Yang, S; Yu, HP | 1 |
| Bian, Q; Chen, JF; Qian, J; Song, L; Sun, H; Wang, XR; Xu, LC | 1 |
| Arnold, JT; Blackman, MR; Le, H; McFann, KK | 1 |
| Hajszan, T; Johansen, JA; Jordan, CL; Leranth, C; MacLusky, NJ | 1 |
| Handa, RJ; Hinds, LR; Lund, TD | 1 |
| Gu, RG; Ma, QZ; Zhou, CW | 1 |
| Edinger, KL; Frye, CA | 1 |
| Hurst, MR; James, JD; Katsiadaki, I; Morris, S; Scott, AP; Squires, C | 1 |
| Dufour, S; Jolly, C; Katsiadaki, I; Le Belle, N; Mayer, I | 1 |
| Chen, JF; Cui, LB; Hong, X; Song, L; Sun, H; Wang, XR; Xu, LC; Xu, XL | 1 |
| Chen, JF; Song, L; Sun, H; Wang, XR; Xu, LC | 1 |
| Bergh, C; Billig, H; Egecioglu, E; Fernandez-Rodriguez, J; Ljungström, K; Shao, R; Thurin-Kjellberg, A; Weijdegård, B; Zhang, FP | 1 |
| Benbrahim-Tallaa, L; Liu, J; Waalkes, MP; Webber, MM | 1 |
| Bottero, S; Kloas, W; Lutz, I; Mandich, A; Urbatzka, R | 1 |
| Chang, CY; Elbi, C; Hager, GL; Hendarwanto, A; Klokk, TI; Kurys, P; Nagaich, AK; Saatcioglu, F; Slagsvold, T | 1 |
| De Rosier, T; Eliason, HC; Ervin, KM; Gowda, K; Kupcho, KR; Marks, BD; Ozers, MS; Qadir, N; Riddle, SM; Shekhani, MS | 1 |
| Fuse, H; Hiyama, T; Ito, T; Kato, S; Kimura, K; Korenaga, S; Sakari, M | 1 |
| Boquan, J; Chaoqun, L; Dehua, Y; Feili, G; Hui, W; Jian, Q; Jie, X; Jinquan, T; Lang, C; Luokun, X; Qiuping, Z; Yanping, J; Yi, S; Youxin, J | 1 |
| Akahoshi, T; Ariga, H; Hayashi, H; Itoh, Y; Miyazawa, K; Okamoto, T; Onozaki, K; Otsuka, T; Takii, T; Waguri-Nagaya, Y; Xu, J | 1 |
| Cafasso, D; Konduri, S; Schwarz, MA; Schwarz, RE | 1 |
| Dong, LJ; Gao, Y; Liu, S; Wang, Y; Yang, J; Yao, Z | 1 |
| Dong, Z; Lu, S; Wang, A | 1 |
| Hashimoto, Y; Ikarashi, T; Nishiyama, T; Takahashi, K; Wako, K | 1 |
| Clapp, TR; Foradori, CD; Handa, RJ; Sandau, US; Werner, SB | 1 |
| Farmer, PB; Gescher, AJ; Greaves, P; Mellon, JK; Pathak, S; Sharma, RA; Singh, R; Steward, WP; Verschoyle, RD | 1 |
| Fernández-Guasti, A; Phillips-Farfán, BV; Romano-Torres, M | 1 |
| Chien, EK; Dailey, TL; Ji, H; Long, V | 1 |
| McCarthy, MM; Nuñez, JL | 1 |
| Han, HJ; Heo, JS; Lee, MY; Lee, SH | 1 |
| Anose, BM; LaGoo, L; Schwendinger, J | 1 |
| Alves, CH; Baltazar, G; Gonçalves, I; Quintela, T; Santos, CR; Saraiva, MJ | 1 |
| Cárdenas, H; Jiménez, E; Pope, WF | 1 |
| Bale, TL; Goel, N; Handa, RJ; Sandau, US; Weiser, MJ | 1 |
| Benedito, S; Bustamante, S; García-Sacristán, A; Hernández, M; Martínez, AC; Navarro-Dorado, J; Orensanz, LM; Prieto, D; Recio, P | 1 |
| Hara, S; Isaacs, JT; Ishioka, J; Kageyama, Y; Nishikawa, K; Tomura, A | 1 |
| Abler, LL; Allgeier, SH; Lin, TM; Moore, RW; Peterson, RE; Vezina, CM | 1 |
| Dubbink, HJ; Hersmus, R; Jenster, G; Lusher, SJ; Molier, M; Trapman, J; van de Wijngaart, DJ | 1 |
| Díaz, M; Gómez, T; González-Montelongo, MC; Marín, R; Marrero-Alonso, J | 1 |
| Chippari, S; Crabtree, JS; Harris, HA; Kenney, T; Kilbourne, EJ; McNally, C; Nagpal, S; Peano, BJ; Thompson, CC; Wang, W; Winneker, RC | 1 |
| Bentov, I; Plymate, SR; Schayek, H; Sun, S; Werner, H | 1 |
| Handa, RJ; Kudwa, AE; López, FJ; McGivern, RF | 1 |
| Walker, WH | 1 |
| Aguilera, CA; Bannoud, N; Carvelli, LF; Morales, CR; Sosa, MA | 1 |
| Dotan, N; Mahajna, J; Wasser, SP | 1 |
| Jin, Y; Liu, ZW; Sun, HY; Tong, da Y; Wen, XQ; Wu, XY; Zhou, FJ | 1 |
| Anonuevo, A; Bingham, B; Gray, M; Innala, L; Myung, C; Viau, V | 1 |
| Bruttocao, A; De Toni, L; Foresta, C; Garolla, A; Gianesello, L; Plebani, M; Scarda, A; Strapazzon, G | 1 |
| Butler, LM; Ingman, WV; Peters, AA; Tilley, WD | 1 |
| Andrieu, T; Baker, ME; Bertolini, R; Frey, BM; Frey, FJ; Nichols, SE; Setoud, R | 1 |
| Kai, L; Levenson, AS | 1 |
| Brosens, JJ; Ishihara, O; Itakura, A; Kajihara, T; Prechapanich, J; Tochigi, H; Uchino, S | 1 |
| Chang, C; Hsu, JW; Izumi, K; Miyamoto, H; Zheng, Y | 1 |
| Chen, R; Chen, S; Dai, R; Duan, C; He, T; Li, H; Li, J; Liu, Y; Wei, M; Yan, D | 1 |
| Buscemi, S; Giammona, G; Pace, A; Piccionello, AP; Picone, P; Pitarresi, G; Triolo, D | 1 |
| Svensson, AI | 1 |
| Jin, Y; Liu, Zw; Sun, Hy; Tong, da Y; Wu, Xy; Zhou, Fj | 1 |
| Liu, JY; Murphy, BD; Tsang, BK; Xue, K | 1 |
| Imasaka, T; Li, X; Miyake, R; Uchimura, T | 1 |
| Imamichi, Y; Ju, Y; Kanno, M; Kawabe, S; Kitano, T; Kuribayashi, M; Matsumura, T; Miyamoto, K; Mizutani, T; Shimada, M; Umezawa, A; Usami, Y; Yamazaki, Y; Yazawa, T | 1 |
| Abbott, DH; Chazenbalk, G; Dumesic, DA; Irge, D; Shah, A; Singh, P | 1 |
| Baker, CJ; Cowie, AM; Hindle, M; Martyniuk, CJ; Ornostay, A | 1 |
| Chuang, CK; Lenka, G; Ng, KF; Pang, ST; Weng, WH | 1 |
| Brambrink, AM; Cheng, J; Cornea, A; Grafe, MR; Hurn, PD; Ivashkova, Y; Murphy, SJ; Vagnerova, K; Young, J; Zhang, W | 1 |
| Dehghan, F; Muniandy, S; Salleh, N; Yusof, A | 1 |
| Golan, M; Levavi-Sivan, B | 1 |
| Bethea, CL; Coleman, K; Phu, A; Phu, K; Reddy, AP | 1 |
| Estill, CT; Meaker, M; Montilla, HJ; Reddy, RC; Roselli, CE; Scheldrup, M; Stormshak, F | 1 |
| Makita, M; Miyano, T | 1 |
| Bethea, CL; Kim, A; Phu, K; Reddy, AP | 1 |
| Cui, H; Du, J; Feng, B; Kang, L; Li, S; Zhang, Y | 1 |
| Casson, P; Hurliman, A; Keller Brown, J; Maille, N; Mandala, M; Osol, G | 1 |
| Chattopadhyay, A; Cox, MB; Sieglaff, DH; Storer Samaniego, C; Suh, JH; Webb, P | 1 |
| Giribabu, N; Muniandy, S; Ramli, NS; Salleh, N | 1 |
| Bhatia, H; Kumar, A | 1 |
| Billig, H; Cui, P; Feng, Y; Guo, YR; Hu, M; Jiang, HY; Li, X; Pishdari, B; Shao, R; Yang, HP | 1 |
| Belikova, Y; Bethea, CL; Mammerella, G; Phu, K | 1 |
| Bogner, J; Hickson, I; Romer, T; Yurlova, L; Zolghadr, K | 1 |
| Chiba, A; Fujiwara, M; Nitta, A | 1 |
| Hara, N; Ishizaki, F; Nishiyama, T; Takeda, K; Tasaki, M; Tomita, Y | 1 |
| El-Shishtawy, KA; Ide, H; Kashiwagi, E; Kawahara, T; Li, Y; Miyamoto, H; Reis, LO; Zheng, Y | 1 |
| Cai, Y; Chew, C; Muñoz, F; Sengelaub, DR | 1 |
| Fenwick, M; Franks, S; Hardy, K; Laird, M; Mora, J; Thomson, K | 1 |
| Alonso-Diez, A; Caceres, S; de Andres, PJ; Illera, JC; Illera, MJ; Monsalve, B; Peña, L; Reuben, JM; Silvan, G; Woodward, WA | 1 |
| Büttner, C; Ekici, AB; Eulenburg, V; Huber, SE; Kornhuber, J; Lenz, B; Mühle, C; Müller, CP; Reichel, M; Zoicas, I | 1 |
| Babayev, SN; Bukulmez, O; Carr, BR; Keller, PW; Park, CW; Word, RA | 1 |
| Abi Ghanem, C; Degerny, C; Ghoumari, AM; Habert, R; Hussain, R; Liere, P; Macklin, WB; Pianos, A; Schumacher, M; Tourpin, S | 1 |
| Huber, SE; Kornhuber, J; Lenz, B; Müller, CP | 1 |
| Rhen, T; Schroeder, A | 1 |
| Akishita, M; Eto, M; Ishida, Y; Ito, K; Kojima, T; Oura, M; Son, BK; Taniguchi, S; Umeda-Kameyama, Y | 1 |
| Amin, A; Bars, C; Boekelheide, K; Carmichael, PL; Dent, MP; Hall, S; Li, H; Madnick, SJ; Martin, FL; Vantangoli Policelli, M | 1 |
| Azhagiya Singam, ER; Durkin, KA; La Merrill, MA; Smith, MT; Tachachartvanich, P | 1 |
| Lawless, J; Wang, S; Zheng, Z | 1 |
| Ishida, M; Islam, MN; Jahan, MR; Masumoto, KH; Mitsushima, D; Nozaki, K; Sakimoto, Y; Shinoda, K; Tarif, AMM; Yanai, A | 1 |
| Baumbach, J; Monks, AD; Ramzan, F; Zovkic, IB | 1 |
| Cheng, YY; Cooper, MS; Desai, R; Handelsman, DJ; Hunt, NJ; Ma, D; Maitz, PK; Parungao, RJ; Shi, H; Simanainen, U; Tan, Q; Tsai, KH; Wang, X; Wang, Y; Xu, Y; Zhang, H | 1 |
| Lorenzetti, S; Mantovani, A; Marcoccia, D; Smeriglio, A; Trombetta, D | 1 |
| Ding, Z; Duan, H; Ge, W; Hu, J; Lv, J; Wang, W; Zeng, J; Zhang, Y; Zhao, X | 1 |
| Cai, Q; Chambon, C; Charlot, A; Duteil, D; Ghaibour, K; Messaddeq, N; Metzger, D; Rerra, AI; Rizk, J; Rovito, D; Schuh, M; Souali-Crespo, S; Zoll, J | 1 |
7 review(s) available for flutamide and dihydrotestosterone
| Article | Year |
|---|---|
Androgen receptors and the molecular basis for the action of antiadrogens in the ventral prostate.
Topics: Androgen Antagonists; Animals; Carrier Proteins; Contraceptive Agents, Male; Cyproterone; Cytosol; Dihydrotestosterone; Flutamide; Genes; Male; Molecular Conformation; Prostate; Protein Binding; Rats; Receptors, Androgen; Receptors, Steroid; RNA; Transcription, Genetic | 1976 |
Potential test systems for chemotherapeutic agents against prostatic cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Antineoplastic Agents; Arginase; Dihydrotestosterone; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Estradiol; Estramustine; Estriol; Estrogens; Flutamide; Haplorhini; Humans; Male; Mice; Neoplasms, Experimental; Prostate; Prostatic Neoplasms; Rats; Testosterone | 1975 |
Combination therapy with flutamide and [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide in stage C and D prostate cancer: today's therapy of choice--rationale and 5-year clinical experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Delayed-Action Preparations; Dihydrotestosterone; Flutamide; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Male; Orchiectomy; Prostate; Prostatic Neoplasms; Triptorelin Pamoate | 1988 |
Treatment of prostate cancer with gonadotropin-releasing hormone agonists.
Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Estrogens; Flutamide; Humans; Luteinizing Hormone; Male; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostatic Neoplasms; Radioimmunoassay; Testosterone | 1986 |
Mechanism of action and pure antiandrogenic properties of flutamide.
Topics: Androgen Antagonists; Androgen-Binding Protein; Animals; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Orchiectomy; Ornithine Decarboxylase; Phosphatidylethanolamine Binding Protein; Prostate; Prostatein; Prostatic Neoplasms; RNA, Messenger; Secretoglobins; Tumor Cells, Cultured; Uteroglobin | 1993 |
Prostate cancer. Primary hormonal treatment.
Topics: Combined Modality Therapy; Cyproterone Acetate; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Orchiectomy; Patient Participation; Prostate; Prostatic Neoplasms; Receptors, Androgen; Testosterone | 1993 |
Monotherapy in advanced prostate cancer: an overview.
Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Cyproterone Acetate; Dihydrotestosterone; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Humans; Imidazolidines; Male; Nitriles; Orchiectomy; Palliative Care; Progesterone Congeners; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Testosterone; Tosyl Compounds | 2004 |
6 trial(s) available for flutamide and dihydrotestosterone
| Article | Year |
|---|---|
Effects of two different medical treatments on dihydrotestosterone content and androgen receptors in human benign prostatic hyperplasia.
Topics: Androgen Antagonists; Anilides; Cell Nucleus; Cyproterone; Cyproterone Acetate; Cytosol; Dihydrotestosterone; Flutamide; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Tamoxifen | 1988 |
The effect of short term treatment with cyproterone acetate or flutamide on the metabolism of 5 alpha-dihydrotestosterone in human testicular tissue.
Topics: Aged; Aged, 80 and over; Anilides; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Male; Middle Aged; Testis | 1988 |
Effect of flutamide or cyproterone acetate on pituitary and testicular hormones in normal men.
Topics: Adult; Anilides; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Estradiol; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Pituitary Function Tests; Pituitary Hormones; Prolactin; Testicular Hormones; Testosterone | 1984 |
[Phase I study of flutamide, a nonsteroidal antiandrogen, in patients with prostatic cancer].
Topics: Administration, Oral; Aged; Aged, 80 and over; Dihydrotestosterone; Drug Administration Schedule; Flutamide; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Prolactin; Prostatic Neoplasms; Testosterone | 1993 |
Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland. International Prostate Health Council (IPHC) Trial Study Group.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Follicle Stimulating Hormone; Goserelin; Humans; Luteinizing Hormone; Male; Middle Aged; Neoplasm Staging; Prostate-Specific Antigen; Prostatic Neoplasms | 1999 |
Reproductive steroid receptors and actions in the locus coeruleus of male macaques: Part of an aggression circuit?
Topics: Aggression; Androgen Antagonists; Androgens; Animals; Corticotropin-Releasing Hormone; Dihydrotestosterone; Dopamine beta-Hydroxylase; Flutamide; Locus Coeruleus; Macaca mulatta; Male; Orchiectomy; Receptors, Steroid; Testosterone; Tyrosine 3-Monooxygenase | 2016 |
302 other study(ies) available for flutamide and dihydrotestosterone
| Article | Year |
|---|---|
Antiandrogenic steroidal sulfonylpyrazoles.
Topics: Androgen Antagonists; Animals; Male; Molecular Structure; Orchiectomy; Organ Size; Pregnanes; Prostate; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Androgen; Structure-Activity Relationship; Testosterone; X-Ray Diffraction | 1990 |
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity | 2009 |
Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators.
Topics: Administration, Oral; Androgen Receptor Antagonists; Androgens; Animals; Azabicyclo Compounds; Dogs; Drug Design; Humans; Ligands; Male; Mice; Microsomes, Liver; Mutation; NIH 3T3 Cells; Orchiectomy; Prostatic Neoplasms; Rats; Receptors, Androgen; Structure-Activity Relationship; Substrate Specificity; Testosterone Propionate | 2009 |
In vitro uptake of 3H testosterone and its conversion to dihydrotestosterone by prostatic carcinoma and other tissues.
Topics: Aged; Culture Techniques; Diethylstilbestrol; Dihydrotestosterone; Flutamide; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Prostate; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone; Tritium | 1976 |
The effect of antiandrogens and stilboestrol on the cytosol receptor in rat prostate.
Topics: Androgen Antagonists; Animals; Chlormadinone Acetate; Cyproterone; Cytosol; Diethylstilbestrol; Dihydrotestosterone; Flutamide; Male; Nandrolone; Prostate; Rats; Receptors, Androgen; Receptors, Steroid | 1977 |
Androgen receptors in benign and malignant prostatic tissue.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Animals; Cyproterone; Dihydrotestosterone; Estrenes; Flutamide; Humans; Male; Prostatic Hyperplasia; Prostatic Neoplasms; Rats; Receptors, Androgen; Receptors, Steroid | 1979 |
Action of a non-steroid anti-androgen, RU 23908, in peripheral and central tissues.
Topics: Androgen Antagonists; Animals; Binding, Competitive; Castration; Cytosol; Dihydrotestosterone; Flutamide; Gonadotropin-Releasing Hormone; Imidazoles; Kinetics; Male; Organ Size; Prostate; Rats; Receptors, Androgen; Receptors, Steroid; Testis; Testosterone | 1979 |
Effect of antiandrogens on the binding of androgen to cytosol and nuclei of hamster sebaceous glands.
Topics: Androgen Antagonists; Androstanes; Androstanols; Animals; Cell Nucleus; Cricetinae; Cyproterone; Cytosol; Dihydrotestosterone; Estrenes; Flutamide; In Vitro Techniques; Male; Prostate; Receptors, Androgen; Receptors, Steroid; Sebaceous Glands; Seminal Vesicles; Steroids, Heterocyclic; Testosterone | 1979 |
Anti-androgenicity of flutamide and its metabolite Sch 16423.
Topics: Anilides; Animals; Castration; Dihydrotestosterone; Flutamide; Male; Prostate; Rats; Receptors, Androgen; Seminal Vesicles; Structure-Activity Relationship; Testosterone | 1979 |
Androgen-uterine interactions: an assessment of androgen interaction with the testosterone- and estrogen-receptor systems and stimulation of uterine growth and progesterone-receptor synthesis.
Topics: Androgen Antagonists; Animals; Binding, Competitive; Cell Nucleus; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Flutamide; Isoxazoles; Organ Size; Phthalimides; Rats; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Testosterone; Uterus | 1979 |
Androgen binding to cytosol and nuclei of hamster sebaceous glands.
Topics: Androgens; Animals; Cell Nucleus; Cricetinae; Cyproterone; Cytosol; Dihydrotestosterone; Estradiol; Flutamide; Male; Progesterone; Receptors, Androgen; Sebaceous Glands | 1978 |
Specific androgen binding in the kidney and estrogen-dependent renal carcinoma of the Syrian hamster.
Topics: Androgens; Animals; Castration; Cell Nucleus; Cricetinae; Cyproterone; Cytosol; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Flutamide; Kidney; Kidney Neoplasms; Liver; Male; Progesterone; Receptors, Androgen; Receptors, Steroid | 1977 |
Evidence of a role of adrogens in follicular maturation.
Topics: Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Cyproterone; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Female; Flutamide; Humans; Hydrocortisone; Hydroxyprogesterones; Hypophysectomy; Organ Size; Ovarian Follicle; Ovary; Pituitary Gland; Progesterone; Rats; Testosterone | 1975 |
Measurement of androgen sensitivity in the human prostate in in vitro three-dimensional histoculture.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Dihydrotestosterone; Flutamide; Histological Techniques; Humans; Male; Prostate; Prostatic Hyperplasia; Receptors, Androgen; Thymidine | 1992 |
The effect of androgen, estrogen, and growth factors on the proliferation of cultured fibroblasts derived from human fetal and adult prostates.
Topics: Cell Division; Cells, Cultured; Dihydrotestosterone; Epidermal Growth Factor; Estradiol; Female; Fetus; Fibroblasts; Flutamide; Genes, fos; Growth Substances; Humans; Immunohistochemistry; Male; Pregnancy; Prostate; Prostatic Hyperplasia; RNA, Messenger | 1992 |
Local hyperthermia for prostatic disease: in vitro studies on human prostatic cancer cell lines.
Topics: Cell Division; Cell Survival; Dihydrotestosterone; DNA, Neoplasm; Flutamide; Humans; Hyperthermia, Induced; Male; Prostatic Neoplasms; Tumor Cells, Cultured | 1992 |
Regulation of androgen receptor mRNA and protein level by steroid hormones in human mammary cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Cyproterone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression Regulation, Neoplastic; Hormones; Humans; Immunohistochemistry; Progesterone Congeners; Radioligand Assay; Receptors, Androgen; RNA, Messenger; Steroids; Tumor Cells, Cultured | 1992 |
Effects of dihydrotestosterone and hydroxyflutamide on androgen receptors in cultured human breast cancer cells (EVSA-T).
Topics: Androgen Antagonists; Breast Neoplasms; Cell Division; Dihydrotestosterone; Flutamide; Humans; Receptors, Androgen; Tumor Cells, Cultured | 1992 |
Adrenal steroidogenesis in the guinea pig: effects of androgens.
Topics: Adrenal Cortex; Androstanes; Animals; Castration; Dihydrotestosterone; Flutamide; Guinea Pigs; Male; Pregnenes; Radioimmunoassay; Steroids; Zona Reticularis | 1992 |
Androgens in relation to prenatal development and postnatal inversion of the gubernacula in rats.
Topics: Androgens; Animals; Dihydrotestosterone; Flutamide; Male; Muscle Development; Muscles; Orchiectomy; Rats; Rats, Inbred Strains; Scrotum; Testis | 1992 |
Effects of flutamide and finasteride on rat testicular descent.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Androstenes; Animals; Azasteroids; Cryptorchidism; Dihydrotestosterone; Epididymis; Female; Finasteride; Flutamide; Gestational Age; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Testis; Testosterone | 1991 |
[The effects of antiprostatic agents on the accessory sex organs of rats treated with adrenal androgens].
Topics: Adrenal Glands; Androgen Antagonists; Androgens; Animals; Castration; Dihydrotestosterone; Flutamide; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Organ Size; Prostate; Rats; Rats, Inbred Strains; Testosterone | 1991 |
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured | 1991 |
Combination of an antiandrogen and a 5 alpha-reductase inhibitor: a further step towards total androgen blockade?
Topics: 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Androstanes; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Drug Interactions; Flutamide; Male; Organ Size; Prostate; Prostatein; Rats; Rats, Inbred Strains; RNA, Messenger; Secretoglobins; Uteroglobin | 1991 |
On the organization of partner preference behavior in female Wistar rats.
Topics: Androgen Antagonists; Animals; Copulation; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Female; Flutamide; Imidazoles; Imidazolidines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Sex Differentiation; Sexual Behavior, Animal; Sexual Maturation; Social Environment; Testosterone | 1991 |
Nonsteroid antiandrogen inhibiting effect on testosterone metabolism in rat prostate and liver.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Dihydrotestosterone; Flutamide; Liver; Male; Orchiectomy; Prostate; Rats; Rats, Inbred Strains; Testosterone | 1990 |
Similarities and differences in progesterone and androgens in modulation of LH, FSH and PRL release: unexpected properties of flutamide.
Topics: Adrenalectomy; Androgens; Anilides; Animals; Dihydrotestosterone; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropins, Equine; Luteinizing Hormone; Mifepristone; Ovariectomy; Ovulation; Progesterone; Prolactin; Rats; Testosterone; Triamcinolone Acetonide | 1990 |
Androgens delay human fetal lung maturation in vitro.
Topics: Androgens; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dihydrotestosterone; Fetal Organ Maturity; Flutamide; Humans; Lung; Phosphatidylcholines; Pulmonary Surfactants | 1990 |
The synthetic androgen mibolerone induces transient suppression of the transformed phenotype in an androgen responsive human prostatic carcinoma cell line.
Topics: Androgen Antagonists; Androgens; Cell Division; Cell Transformation, Neoplastic; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Male; Nandrolone; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tumor Cells, Cultured | 1990 |
Effect of combined androgen blockade with an LHRH agonist and flutamide in one severe case of male exhibitionism.
Topics: Administration, Oral; Adult; Anilides; Dihydrotestosterone; Drug Therapy, Combination; Exhibitionism; Flutamide; Follow-Up Studies; Gender Identity; Gonadotropin-Releasing Hormone; Humans; Injections, Subcutaneous; Male; Masturbation; MMPI; Paraphilic Disorders; Sexual Behavior; Sperm Count; Sperm Motility; Testosterone; Triptorelin Pamoate | 1990 |
Aromatization mediates aggressive behavior in quail.
Topics: 5-alpha Reductase Inhibitors; Aggression; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Azasteroids; Behavior, Animal; Coturnix; Dihydrotestosterone; Estradiol; Female; Flutamide; Hypothalamus; Male; Motor Activity; Nitromifene; Preoptic Area; Quail; Testosterone | 1990 |
The proliferative effect of "anti-androgens" on the androgen-sensitive human prostate tumor cell line LNCaP.
Topics: Androgens; Antibodies; Cell Division; Dihydrotestosterone; Estradiol; Flutamide; Humans; Male; Nandrolone; Prostatic Neoplasms; Receptors, Androgen; Testosterone Congeners; Tumor Cells, Cultured | 1990 |
Regulation of progesterone-binding breast cyst protein GCDFP-24 secretion by estrogens and androgens in human breast cancer cells: a new marker of steroid action in breast cancer.
Topics: Androgens; Apolipoproteins; Apolipoproteins D; Binding, Competitive; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Glycoproteins; Humans; Kinetics; Membrane Transport Proteins; Neoplasm Proteins; Progesterone; Tumor Cells, Cultured | 1990 |
Inhibitory effect of androgen on cell death of mouse uterine epithelium.
Topics: Animals; Cell Survival; Dihydrotestosterone; Epithelial Cells; Estradiol; Female; Flutamide; Idoxuridine; Iodine Radioisotopes; Mice; Mice, Inbred C57BL; Ovariectomy; Progesterone; Uterus | 1990 |
Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer.
Topics: Adrenal Glands; Animals; Chlormadinone Acetate; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Megestrol Acetate; Organ Size; Ornithine Decarboxylase; Progesterone Congeners; Prostate; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Spironolactone | 1987 |
Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture.
Topics: Androgens; Animals; Cell Division; Chlormadinone Acetate; Dihydrotestosterone; Flutamide; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Megestrol; Mice; Progestins; Spironolactone; Tumor Cells, Cultured | 1988 |
5 alpha-dihydrotestosterone has nonspecific effects on membrane channels and possible genomic effects on ACh-activated channels.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Autoradiography; Bungarotoxins; Butyrylcholinesterase; Cells, Cultured; Dihydrotestosterone; Flutamide; Histocytochemistry; Ion Channels; Kinetics; Male; Membrane Potentials; Muscles; Organ Specificity; Receptors, Androgen; Tritium; Xenopus laevis | 1989 |
Effect of 5 alpha-dihydrotestosterone and flutamide on the facilitation of lordosis by LHRH and naloxone in estrogen-primed female rats.
Topics: Anilides; Animals; Dihydrotestosterone; Estradiol; Female; Flutamide; Gonadotropin-Releasing Hormone; Naloxone; Ovariectomy; Posture; Progesterone; Rats; Sexual Behavior, Animal; Substance P | 1989 |
Inhibitory effect of androgens on DMBA-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Inbred Strains; Uterus | 1989 |
Androgens directly stimulate proliferation of bone cells in vitro.
Topics: Alkaline Phosphatase; Androgens; Animals; Binding, Competitive; Cell Count; Cell Differentiation; Cell Division; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; DNA; Dose-Response Relationship, Drug; Fluoxymesterone; Flutamide; Humans; Methenolone; Mice; Osteoblasts; Testosterone; Tumor Cells, Cultured | 1989 |
Estradiol-progesterone-induced growth of the rat dorsolateral prostate: effects on protein phosphorylation.
Topics: Animals; Calcium; Cyclic AMP; Dihydrotestosterone; Estradiol; Flutamide; Male; Orchiectomy; Organ Size; Phospholipids; Phosphorylation; Progesterone; Prostate; Protein Kinases; Proteins; Rats; Rats, Inbred Strains | 1989 |
Progestins and androgens stimulate lipid accumulation in T47D breast cancer cells via their own receptors.
Topics: Acetates; Breast Neoplasms; Dihydrotestosterone; Dose-Response Relationship, Drug; Fatty Acids; Flutamide; Humans; In Vitro Techniques; Lipid Metabolism; Microscopy, Electron; Mifepristone; Norpregnadienes; Promegestone; Receptors, Androgen; Receptors, Progesterone; Triglycerides; Tumor Cells, Cultured | 1989 |
Effects of castration, androgen replacement and flutamide treatment on the contractile function of the rat prostate.
Topics: Anilides; Animals; Dihydrotestosterone; Electric Stimulation; Flutamide; Male; Muscle Contraction; Orchiectomy; Prostate; Rats; Rats, Inbred Strains; Testosterone | 1989 |
Comparative effects of androgens and catecholestrogens on progesterone production by porcine granulosa cells.
Topics: 2-Methoxyestradiol; Androstenedione; Animals; Cell Count; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Ovum; Progesterone; Swine; Testosterone | 1988 |
Testosterone suppression of ornithine decarboxylase activity in rat Sertoli cells.
Topics: Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Enzyme Induction; Estradiol; Flutamide; Follicle Stimulating Hormone; Male; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Sertoli Cells; Testosterone | 1988 |
Castration levels of plasma testosterone have potent stimulatory effects on androgen-sensitive parameters in the rat prostate.
Topics: Animals; Dihydrotestosterone; Flutamide; Male; Orchiectomy; Organ Size; Ornithine Decarboxylase; Prostate; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Seminal Vesicles; Testosterone | 1988 |
Opiate receptor ontogeny in the rat medial preoptic area is androgen-dependent.
Topics: Androgens; Animals; Dihydrotestosterone; Estrogens; Female; Flutamide; Male; Naloxone; Neurons; Oils; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Opioid; Tamoxifen | 1988 |
Influence of sex steroid hormones on rat growth hormone-releasing factor and somatostatin in dispersed pituitary cells.
Topics: Animals; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Growth Hormone-Releasing Hormone; Methyltestosterone; Norethindrone; Pituitary Gland; Progesterone; Rats; Rats, Inbred Strains; Somatostatin; Testosterone | 1986 |
Acid phosphatase activity: a marker of androgen action in prostate explant cultures.
Topics: Acid Phosphatase; Animals; Cells, Cultured; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Flutamide; Hydrocortisone; Male; Prostate; Rats; Rats, Inbred Strains | 1987 |
Effect of cyproterone acetate in comparison to flutamide and megestrol acetate on the ventral prostate, seminal vesicle, and adrenal glands of adult male rats.
Topics: Adrenal Glands; Androgen Antagonists; Animals; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Male; Megestrol; Megestrol Acetate; Orchiectomy; Organ Size; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles | 1987 |
Relative effectiveness of alternative androgen withdrawal therapies in initiating regression of rat prostate.
Topics: Anilides; Animals; Cyproterone; Cyproterone Acetate; Diethylstilbestrol; Dihydrotestosterone; Flutamide; Gonadotropin-Releasing Hormone; Imidazoles; Imidazolidines; Leuprolide; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen | 1988 |
Hormonal changes induced by the pure antiandrogen flutamide in postmenopausal women with advanced breast cancer.
Topics: Anilides; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Flutamide; Gonadal Steroid Hormones; Hormones; Humans; Middle Aged; Time Factors | 1988 |
Inhibition of 20 alpha-hydroxysteroid dehydrogenase activity by follicle-stimulating hormone and androgens in cultured rat granulosa cells: a search for the mechanism of action.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Dihydrotestosterone; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; Rats; Rats, Inbred Strains; Testosterone | 1985 |
Hormonal agents and treatment of cancer.
Topics: Androgens; Breast Neoplasms; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Female; Flutamide; Hormones; Humans; Male; Neoplasms, Hormone-Dependent; Progestins; Prostatic Neoplasms; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen | 1986 |
Estrogens, progestogens, and androgens enhance the follicle-stimulating hormone-stimulated plasminogen activator production by cultured rat granulosa cells.
Topics: Androgens; Animals; Cells, Cultured; Dihydrotestosterone; Estradiol; Estrenes; Estrogens; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Mifepristone; Plasminogen Activators; Progesterone; Rats; Testosterone | 1987 |
Differential responses of sex steroid target tissues of rats treated with 4-hydroxyandrostenedione.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Kinetics; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Uterus | 1988 |
Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line.
Topics: Androgen Antagonists; Androstenedione; Breast Neoplasms; Cell Division; Cell Line; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Flutamide; Humans; Piperidines; Raloxifene Hydrochloride; Receptors, Androgen; Receptors, Estrogen; Testosterone | 1988 |
Effects of the antiandrogens cyproterone acetate and flutamide on male reproductive behavior in a lizard (Anolis sagrei).
Topics: Aggression; Anilides; Animals; Cyproterone; Dihydrotestosterone; Female; Flutamide; Lizards; Male; Organ Size; Sexual Behavior, Animal; Social Dominance; Testis; Testosterone | 1987 |
Identification and androgen regulation of two proteins released by T47D human breast cancer cells.
Topics: Androgens; Antibodies, Monoclonal; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Line; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression Regulation; Glycoproteins; Humans; Membrane Transport Proteins; Molecular Weight; Neoplasm Proteins; Promegestone; Receptors, Androgen; Seminal Plasma Proteins; Zn-Alpha-2-Glycoprotein | 1987 |
Androgen dependence of the Dunning R3327G cell line in monolayer culture.
Topics: Androgen Antagonists; Androgens; Animals; Cell Division; Cell Line; Dihydrotestosterone; Flutamide; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Rats; Tumor Cells, Cultured | 1987 |
Endocrine-responsive pancreatic carcinoma: steroid binding and cytotoxicity studies in human tumor cell lines.
Topics: Aminoglutethimide; Animals; Azasteroids; Breast Neoplasms; Cell Cycle; Cell Line; Danazol; Dexamethasone; Dihydrotestosterone; Estradiol; Flutamide; Humans; Pancreatic Neoplasms; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Tamoxifen | 1986 |
Development of androgen resistance in mouse mammary tumor cells can be prevented by the antiandrogen flutamide.
Topics: Anilides; Animals; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Resistance; Flutamide; Male; Mammary Neoplasms, Experimental; Mice; Orchiectomy; Prostatic Neoplasms | 1987 |
Rationale for blockade of adrenal as well as testicular androgens in the treatment of advanced prostate cancer.
Topics: Adrenal Glands; Androgen Antagonists; Dihydrotestosterone; Estrogens; Flutamide; Gonadotropin-Releasing Hormone; Humans; Male; Megestrol; Megestrol Acetate; Prostatic Neoplasms; Testis | 1985 |
Control of granulosa cell lactate production by follicle-stimulating hormone and androgen.
Topics: Androgens; Animals; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Synergism; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Lactates; Osmolar Concentration; Progesterone; Rats; Rats, Inbred Strains; Testosterone; Time Factors | 1985 |
Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate.
Topics: Adrenal Glands; Anilides; Animals; Cyproterone; Dihydrotestosterone; Flutamide; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Megestrol; Orchiectomy; Organ Size; Prostate; Rats; Rats, Inbred Strains | 1985 |
The effects of flutamide on total DHT and nuclear DHT levels in the human prostate.
Topics: Acid Phosphatase; Administration, Oral; Anilides; Cell Nucleus; Dihydrotestosterone; Flutamide; Humans; Male; Prostate; Prostatic Hyperplasia; Testosterone | 1981 |
Metabolism of tritiated C19 steroids by Shionogi mouse mammary tumors.
Topics: Androgens; Androstenediols; Androstenedione; Androsterone; Animals; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Flutamide; Male; Mammary Neoplasms, Experimental; Mice; Steroid Isomerases; Testosterone | 1984 |
Sex-specific action of antiandrogens on androgen induced changes in hepatic microsomal 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase activity in the rat.
Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Anilides; Animals; Castration; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Female; Flutamide; Male; Microsomes, Liver; Organ Size; Oxidoreductases; Rats; Sex Factors | 1981 |
Action of prolactin in regressing prostate: independent of action mediated by androgen receptors.
Topics: Animals; Castration; Dihydrotestosterone; Flutamide; Male; Organ Size; Pituitary Gland; Prolactin; Prostate; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Steroid | 1984 |
Antiandrogenic effects of oestradiol on enzyme activities of hepatic steroid metabolism.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Animals; Castration; Cyproterone; Dihydrotestosterone; Estradiol; Female; Flutamide; Male; Microsomes, Liver; Oxidoreductases; Rats; Rats, Inbred Strains | 1983 |
Inhibition of estrogen-activated sexual behavior by androgens.
Topics: Androgens; Animals; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Flutamide; Male; Posture; Rats; Rats, Inbred Strains; Receptors, Androgen; Sexual Behavior, Animal; Testosterone | 1983 |
Effects of an anti-androgen and 5 alpha-reductase inhibitors on estrus duration in the cycling female rat.
Topics: Anilides; Animals; Azasteroids; Castration; Dihydrotestosterone; Estradiol; Estrus; Female; Flutamide; Organ Size; Ovary; Posture; Pregnancy; Rats; Sexual Behavior, Animal; Steroids, Heterocyclic; Testosterone; Uterus | 1983 |
Androgens regulate brain aromatase activity in adult male rats through a receptor mechanism.
Topics: Androgens; Animals; Aromatase; Castration; Dihydrotestosterone; Drug Implants; Flutamide; Genitalia, Male; Hypothalamus; Male; Organ Size; Oxidoreductases; Preoptic Area; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Androgen; Receptors, Steroid; Testosterone | 1984 |
Estrogen, progesterone, and androgen-binding sites in renal cell carcinoma. Observations obtained in Phase II trial of flutamide.
Topics: Adenocarcinoma; Adult; Aged; Anilides; Binding Sites; Dihydrotestosterone; Drug Evaluation; Estradiol; Female; Flutamide; Humans; Kidney Neoplasms; Male; Middle Aged; Progesterone; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid | 1984 |
Effect of androgens on the ovarian morphology of the hypophysectomized rat.
Topics: Animals; Diethylstilbestrol; Dihydrotestosterone; Female; Flutamide; Hypophysectomy; Ovarian Follicle; Rats; Testosterone | 1983 |
Dihydrotestosterone inhibits fetal rabbit pulmonary surfactant production.
Topics: Animals; Body Weight; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; Infant, Newborn; Lung; Male; Pregnancy; Pulmonary Surfactants; Rabbits; Respiratory Distress Syndrome, Newborn; Sex Factors | 1982 |
Androgen control of cytosol progesterone receptor levels in the MT-W9B transplantable mammary tumor in the rat.
Topics: Androgens; Animals; Castration; Cytosol; Dihydrotestosterone; Estradiol; Female; Flutamide; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred WF; Receptors, Progesterone; Sex Factors; Testosterone; Uterus | 1982 |
Modulation of hypothalamic luteinizing hormone-releasing hormone levels by intracranial and subcutaneous implants of gonadal steroids in castrated rats: effects of androgen and estrogen antagonists.
Topics: Anilides; Animals; Castration; Dihydrotestosterone; Drug Implants; Estradiol; Feedback; Flutamide; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Male; Nafoxidine; Pituitary Gland; Pyrrolidines; Rats; Testosterone | 1980 |
Biological activities of a new steroidal inhibitor of delta 4-5 alpha-reductase.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Azasteroids; Body Weight; Dihydrotestosterone; Dose-Response Relationship, Drug; Estrone; Female; Feminization; Fertility; Flutamide; Male; Organ Size; Ovary; Oxidoreductases; Prolactin; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles; Steroids, Heterocyclic; Uterus | 1982 |
The effects of androgen and antiandrogen on dominance and aggressiveness in male red-winged blackbirds.
Topics: Aggression; Anilides; Animals; Birds; Cholesterol; Dihydrotestosterone; Drug Implants; Flutamide; Humans; Luteinizing Hormone; Male; Social Dominance; Testosterone; Vocalization, Animal | 1980 |
Danazol suppression of luteinizing hormone secretion: a role for danazol-androgen receptor interaction within the brain-pituitary complex.
Topics: Amygdala; Animals; Brain; Danazol; Dihydrotestosterone; Estradiol; Female; Flutamide; Hypothalamus; Luteinizing Hormone; Male; Pituitary Gland; Pregnadienes; Preoptic Area; Rats; Receptors, Androgen; Receptors, Steroid; Time Factors | 1981 |
Response of rat ventral prostate to a new and novel 5 alpha-reductase inhibitor.
Topics: 5-alpha Reductase Inhibitors; Aging; Androgens; Animals; Azasteroids; Castration; Dihydrotestosterone; Flutamide; Kinetics; Male; Organ Size; Oxidoreductases; Progesterone; Prostate; Rats; Seminal Vesicles; Steroids, Heterocyclic; Testosterone | 1981 |
Antiandrogen effects on androgen-responsive mammary tumour cells in culture.
Topics: Anilides; Animals; Cell Division; Cells, Cultured; Cyproterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Mammary Neoplasms, Experimental; Mice; Receptors, Androgen; Testosterone | 1981 |
The role of the androgen receptor in erythropoiesis.
Topics: Animals; Dihydrotestosterone; DNA Replication; Erythrocytes; Erythropoiesis; Female; Flutamide; Hematopoietic Stem Cells; Iron; Mice; Mice, Mutant Strains; Receptors, Androgen; Receptors, Steroid; Species Specificity | 1981 |
Hormonal regulation of penile erection in castrated male rats.
Topics: Animals; Castration; Dihydrotestosterone; Ejaculation; Estradiol; Flutamide; Gonadal Steroid Hormones; Male; Penis; Rats; Sexual Behavior, Animal; Testosterone | 1980 |
Effect of anti-androgen and 5 alpha-reductase inhibitor on hormone-induced sexual behavior during pregnancy in the rat.
Topics: 5-alpha Reductase Inhibitors; Androstenes; Animals; Castration; Dihydrotestosterone; Estradiol; Female; Flutamide; Male; Posture; Pregnancy; Pregnancy, Animal; Rats; Sexual Behavior, Animal; Testosterone | 1980 |
Inhibitory effect of hydroxyflutamide plus tamoxifen on oestradiol-induced growth of MCF-7 breast cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Dihydrotestosterone; Drug Synergism; Estradiol; Estrogen Antagonists; Flutamide; Humans; Neoplasms, Hormone-Dependent; Tamoxifen; Tumor Cells, Cultured | 1995 |
In vivo and in vitro effects of androgen on fibroblast growth factor-2 concentrations in the human prostate.
Topics: Androgen Antagonists; Cell Division; Culture Techniques; Dihydrotestosterone; Fibroblast Growth Factor 2; Flutamide; Humans; Male; Megestrol; Megestrol Acetate; Orchiectomy; Prostate; Prostatic Hyperplasia; Radioimmunoassay | 1994 |
Growth of LNCaP human prostate cancer cells is stimulated by estradiol via its own receptor.
Topics: Androgen Antagonists; Base Sequence; Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Cytosol; Dihydrotestosterone; DNA Primers; DNA, Neoplasm; Estradiol; Female; Flutamide; Gene Expression; Humans; Kinetics; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostate-Specific Antigen; Prostatic Neoplasms; Radioligand Assay; Receptors, Estradiol; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Atypical androgen receptor in the human melanoma cell line IIB-MEL-J.
Topics: Androgen Antagonists; Animals; Antibodies, Monoclonal; Antineoplastic Agents, Hormonal; Binding, Competitive; Cell Division; Dihydrotestosterone; Estradiol; Flutamide; Humans; Hydrocortisone; Immunohistochemistry; Male; Melanoma; Metribolone; Mice; Mice, Nude; Progesterone; Receptors, Androgen; Testosterone; Tumor Cells, Cultured | 1995 |
Sex steroids up-regulate E-cadherin expression in hormone-responsive LNCaP human prostate cancer cells.
Topics: Androgen Antagonists; Cadherins; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Flutamide; Fulvestrant; Gonadal Steroid Hormones; Humans; Immunoblotting; Immunohistochemistry; Male; Prostatic Neoplasms | 1995 |
Effect of medroxyprogesterone acetate (MPA) and serum factors on cell proliferation in primary cultures of an MPA-induced mammary adenocarcinoma.
Topics: Adenocarcinoma; Androgen Antagonists; Animals; Blood Physiological Phenomena; Cell Division; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mifepristone; Ovariectomy; Progesterone; Tumor Cells, Cultured | 1995 |
Androgen receptor antagonist versus agonist activities of the fungicide vinclozolin relative to hydroxyflutamide.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Binding, Competitive; Cell Line; Dihydrotestosterone; DNA; Flutamide; Fungicides, Industrial; Humans; Kinetics; Male; Oxazoles; Receptors, Androgen; Recombinant Proteins; Reproduction; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Benign prostatic hyperplasia in a transgenic mouse: a new hormonally sensitive investigatory model.
Topics: 5-alpha Reductase Inhibitors; Androstenes; Animals; Azasteroids; Dihydrotestosterone; Disease Models, Animal; Fibroblast Growth Factor 3; Fibroblast Growth Factors; Finasteride; Flutamide; Genes, Viral; Male; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Orchiectomy; Phenotype; Prostate; Prostatic Hyperplasia; Proto-Oncogene Proteins; Sexual Maturation; Testosterone | 1993 |
Androgen treatment decreases estrogen receptor binding in the ventromedial nucleus of the rat brain: a quantitative in vitro autoradiographic analysis.
Topics: Adrenalectomy; Animals; Autoradiography; Castration; Cerebral Ventricles; Dihydrotestosterone; Female; Flutamide; In Vitro Techniques; Male; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sex Characteristics; Ventromedial Hypothalamic Nucleus | 1994 |
Growth inhibition of DMBA-induced rat mammary carcinomas by the antiandrogen flutamide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovary; Progesterone; Rats; Rats, Sprague-Dawley; Uterus | 1995 |
Androgens rapidly increase the cytosolic calcium concentration in Sertoli cells.
Topics: Androgen Antagonists; Androgens; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Dihydrotestosterone; Drug Synergism; Finasteride; Flutamide; Follicle Stimulating Hormone; Kinetics; Male; Progesterone; Rats; Rats, Wistar; Sertoli Cells; Spermatogenesis; Testosterone; Time Factors | 1995 |
Androgens induce divergent proliferative responses in human breast cancer cell lines.
Topics: Androgen Receptor Antagonists; Androgens; Breast Neoplasms; Cell Division; Dihydrotestosterone; Flutamide; Humans; Imidazoles; Imidazolidines; Nandrolone; Oligonucleotides, Antisense; Receptors, Androgen; Tumor Cells, Cultured | 1995 |
The androgen receptor of the urogenital tract of the fetal rat is regulated by androgen.
Topics: Androgens; Animals; Blotting, Western; Dihydrotestosterone; Female; Flutamide; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Urogenital System | 1994 |
Finasteride dose-dependently reduces the proliferation rate of the LnCap human prostatic cancer cell line in vitro.
Topics: Androgen Antagonists; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Finasteride; Flutamide; Humans; Linear Models; Male; Prostatic Neoplasms; Testosterone; Tumor Cells, Cultured | 1995 |
Androgen directs sexual differentiation of laryngeal innervation in developing Xenopus laevis.
Topics: Animals; Axons; Dihydrotestosterone; Female; Flutamide; Laryngeal Muscles; Laryngeal Nerves; Male; Microscopy, Electron; Muscle Development; Sex Differentiation; Testosterone; Xenopus laevis | 1994 |
5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
Topics: Androstenediol; Breast Neoplasms; Cell Division; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured | 1994 |
Juvenile nasopharyngeal fibroma: androgen receptors and their significance for tumor growth.
Topics: Cell Division; Child; Cholestenone 5 alpha-Reductase; Cyproterone; Cyproterone Acetate; Dihydrotestosterone; Fibroblasts; Fibroma; Flutamide; Humans; Male; Nasopharyngeal Neoplasms; Oxidoreductases; Receptors, Androgen; Scrotum; Skin; Testosterone; Tritium; Tumor Cells, Cultured | 1994 |
Androgen receptors and hormone sensitivity of a human prostatic cancer cell line (PC-3) are modulated by natural beta-interferon.
Topics: Androgen Antagonists; Androgens; Cell Cycle; Cell Division; Dihydrotestosterone; Drug Resistance; Flutamide; Humans; Immunohistochemistry; Interferon-beta; Male; Prostatic Neoplasms; Receptors, Androgen; Tumor Cells, Cultured | 1994 |
Antiandrogens inhibit human androgen receptor-dependent gene transcription activation in the human prostate cancer cells LNCaP.
Topics: Amino Acid Sequence; Androgen Antagonists; Binding, Competitive; Blotting, Western; Chloramphenicol O-Acetyltransferase; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression Regulation, Viral; Humans; Imidazoles; Imidazolidines; Male; Mammary Tumor Virus, Mouse; Molecular Sequence Data; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Effect of early exposure of flutamide on subsequent growth of transplantable rat prostatic tumor (dunning R-3327).
Topics: Animals; Cell Division; Dihydrotestosterone; Estradiol; Female; Flutamide; Male; Neoplasm Transplantation; Organ Size; Prostate; Prostatic Neoplasms; Rats; Seminal Vesicles; Testis; Testosterone; Time Factors | 1994 |
Interaction of antiandrogen-androgen receptor complexes with DNA and transcription activation.
Topics: Androgen Antagonists; Animals; Binding, Competitive; Blotting, Western; Cell Line; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; Cyproterone Acetate; Dihydrotestosterone; DNA; Flutamide; Gene Expression Regulation; Humans; Imidazoles; Imidazolidines; Kidney; Kinetics; Mammary Tumor Virus, Mouse; Metribolone; Receptors, Androgen; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection | 1993 |
Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre- and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Animals; Animals, Newborn; Brain Chemistry; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Female; Finasteride; Flutamide; Hypothalamus; Luteinizing Hormone; Male; Pituitary Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1993 |
Androgens induce prolactin production by human endometrial stromal cells in vitro.
Topics: Adult; Androgen Receptor Antagonists; Cells, Cultured; Dihydrotestosterone; Endometrium; Female; Flutamide; Humans; Middle Aged; Osmolar Concentration; Prolactin; Stromal Cells; Testosterone | 1994 |
Suppression of sodium channel function in differentiating C2 muscle cells stably overexpressing rat androgen receptors.
Topics: Acetylcholine; Androgen Antagonists; Animals; Bungarotoxins; Cell Differentiation; Cell Line; Dihydrotestosterone; Flutamide; Gene Expression; Metribolone; Mice; Muscles; Rats; Receptors, Androgen; Receptors, Cholinergic; Sodium Channels; Transfection | 1994 |
Effects of androgens on isolated rat uterus.
Topics: Animals; Cycloheximide; Cyproterone Acetate; Dactinomycin; Dihydrotestosterone; Drug Interactions; Female; Flutamide; In Vitro Techniques; Muscle Contraction; Rats; Rats, Wistar; Uterus | 1993 |
Inhibitory effects of estrogen, progesterone, androgen and glucocorticoid on death of neonatal mouse uterine epithelial cells induced to proliferate by estrogen.
Topics: Animals; Apoptosis; Cell Division; Dexamethasone; Dihydrotestosterone; DNA; Electrophoresis, Agar Gel; Epithelial Cells; Epithelium; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Mice; Mice, Inbred BALB C; Mifepristone; Ovariectomy; Progesterone; Uterus | 1993 |
Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells.
Topics: 17-Hydroxysteroid Dehydrogenases; Breast Neoplasms; Dexamethasone; Dihydrotestosterone; Estradiol; Estrone; Flutamide; Humans; Kinetics; Medroxyprogesterone Acetate; Receptors, Androgen; Tumor Cells, Cultured | 1993 |
Sex steroids induced up-regulation of 1,25-(OH)2 vitamin D3 receptors in T 47D breast cancer cells.
Topics: Breast Neoplasms; Calcitriol; Dihydrotestosterone; Estradiol; Flutamide; Humans; Receptors, Androgen; Receptors, Calcitriol; Receptors, Estrogen; Receptors, Steroid; Tamoxifen; Tumor Cells, Cultured; Up-Regulation | 1993 |
Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA.
Topics: 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Androgens; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Flutamide; In Situ Hybridization; Male; Orchiectomy; Organ Size; Phosphatidylethanolamine Binding Protein; Prostate; Prostatein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Secretoglobins; Uteroglobin | 1993 |
Effects of androgens on proliferation and progesterone receptor levels in T47D human breast cancer cells.
Topics: Androgens; Breast Neoplasms; Cell Division; Dehydroepiandrosterone; Dihydrotestosterone; Down-Regulation; Estradiol; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1993 |
Androgens contribute to the stimulation of cancellous bone formation by ovarian hormones in female rats.
Topics: Animals; Body Weight; Bone and Bones; Bone Resorption; Dihydrotestosterone; Diphosphonates; Female; Flutamide; Organ Size; Osteoclasts; Ovariectomy; Pamidronate; Rats; Rats, Wistar; Tibia; Uterus | 1996 |
Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cell Line; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Dihydrotestosterone; DNA-Binding Proteins; Flutamide; Humans; Male; Molecular Sequence Data; Nuclear Receptor Coactivators; Oncogene Proteins; Prostate; Prostatic Neoplasms; Receptors, Androgen; Receptors, Steroid; Recombinant Proteins; RNA, Messenger; Testosterone; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
Hormonal basis for the gender difference in epidermal barrier formation in the fetal rat. Acceleration by estrogen and delay by testosterone.
Topics: Animals; Diethylstilbestrol; Dihydrotestosterone; Epidermal Cells; Epidermis; Female; Fetus; Flutamide; Gestational Age; Lung; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Sprague-Dawley; Sex Characteristics; Skin | 1996 |
Developmental pattern and regulation by androgens of androgen receptor expression in the urogenital tract of the rat.
Topics: Androgen Antagonists; Androgens; Animals; Dihydrotestosterone; Epididymis; Female; Flutamide; Gestational Age; Immunohistochemistry; Male; Pregnancy; Rats; Rats, Wistar; Receptors, Androgen; Seminal Vesicles; Urogenital System; Vas Deferens; Wolffian Ducts | 1995 |
Androgen-like and anti-androgen-like effects of antiprogestins in human mammary cancer cells.
Topics: Androgen Antagonists; Antineoplastic Agents; Binding, Competitive; Breast Neoplasms; Cell Division; Dihydrotestosterone; Estrenes; Flutamide; Gonanes; Humans; Mifepristone; Models, Biological; Progestins; Receptors, Androgen; Transfection; Tumor Cells, Cultured | 1996 |
Androgen independence of primary epithelial cultures of the prostate is associated with a down-regulation of androgen receptor gene expression.
Topics: Androgen Antagonists; Androgens; Base Sequence; Blotting, Northern; Cell Division; Dihydrotestosterone; DNA, Neoplasm; Dose-Response Relationship, Drug; Down-Regulation; Epithelium; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Polymerase Chain Reaction; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Transfection; Tumor Cells, Cultured | 1996 |
Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma.
Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Leuprolide; Luteinizing Hormone; Male; Organ Size; Pituitary Gland, Anterior; Prostate; Prostatic Neoplasms; Random Allocation; Rats; Seminal Vesicles; Testis; Testosterone | 1997 |
Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.
Topics: Androgen Antagonists; Androgens; Anilides; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Division; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Metribolone; Nandrolone; Nitriles; Receptors, Androgen; Testosterone; Testosterone Congeners; Tosyl Compounds; Transfection; Tumor Cells, Cultured | 1997 |
Non-steroidal L-245,976 acts as a classical antiandrogen in vitro.
Topics: Amides; Androgen Antagonists; Androgen-Binding Protein; Androgens; Aniline Compounds; Animals; Cell Division; Cell Line; CHO Cells; Colorimetry; Cricetinae; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flutamide; Formazans; Humans; Male; Receptors, Androgen; Recombinant Proteins; Testosterone; Tetrazolium Salts; Thiazoles; Transcriptional Activation; Transfection; Vas Deferens | 1997 |
Cyproterone acetate displaces opiate binding in mouse brain.
Topics: Androgen Antagonists; Animals; Binding, Competitive; Brain; Cyproterone Acetate; Dihydrotestosterone; Diprenorphine; Flutamide; Isotope Labeling; Lethal Dose 50; Male; Mice; Narcotic Antagonists; Progesterone; Receptors, Opioid | 1997 |
Interaction of mouse placental lactogens and androgens in regulating progesterone release in cultured mouse luteal cells.
Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Animals; Aromatase Inhibitors; Cattle; Cells, Cultured; Cycloheximide; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fadrozole; Female; Flutamide; Luteal Cells; Mice; Placental Lactogen; Pregnancy; Progesterone; Prolactin; Protein Synthesis Inhibitors; Rabbits; Testosterone | 1997 |
Development and characterization of a conditionally immortalized human osteoblastic cell line stably transfected with the human androgen receptor gene.
Topics: Androgen Antagonists; beta-Galactosidase; Cell Line; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Clone Cells; Dihydrotestosterone; Flutamide; Gene Expression; Genes; Genetic Vectors; Humans; Osteoblasts; Protein Binding; Receptors, Androgen; RNA, Messenger; Transfection | 1997 |
Concerted stimulation of rat granulosa cell deoxyribonucleic acid synthesis by sex steroids and follicle-stimulating hormone.
Topics: Androgen Antagonists; Androgens; Androstenedione; Androsterone; Animals; Bucladesine; Cells, Cultured; Diethylstilbestrol; Dihydrotestosterone; DNA; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Insulin; Insulin-Like Growth Factor I; Kinetics; Medroxyprogesterone; Ovary; Progesterone; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Testosterone; Thymidine | 1997 |
Differential in vivo regulation of steroid hormone receptor activation by Cdc37p.
Topics: Amino Acid Sequence; Androgen Antagonists; Cell Cycle Proteins; Chaperonins; Desoxycorticosterone; Dihydrotestosterone; Drosophila Proteins; Flutamide; Genes, Reporter; Humans; Ligands; Molecular Chaperones; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Receptors, Androgen; Receptors, Glucocorticoid; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Temperature; Thermodynamics; Transcriptional Activation | 1997 |
Identification of androgen-regulated genes in mouse kidney by representational difference analysis and random arbitrarily primed polymerase chain reaction.
Topics: Androgen Antagonists; Androgens; Animals; Dihydrotestosterone; Female; Flutamide; Gene Expression Regulation; Genetic Techniques; Kidney; Male; Mice; Mice, Inbred C57BL; Random Amplified Polymorphic DNA Technique; Transcription, Genetic | 1998 |
Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland.
Topics: Androgen Antagonists; Androgens; Animals; Benzopyrans; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Flutamide; Mammary Glands, Animal; Medroxyprogesterone; Ovariectomy; Propionates; Rats; Rats, Sprague-Dawley | 1998 |
Regulation of gonadotropin-releasing hormone (GnRH) gene expression by 5alpha-dihydrotestosterone in GnRH-secreting GT1-7 hypothalamic neurons.
Topics: Animals; Cells, Cultured; Dihydrotestosterone; Flutamide; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Mice; Neurons; Receptors, Androgen; RNA, Messenger | 1998 |
The role of transforming growth factor-beta1, -beta2, and -beta3 in androgen-responsive growth of NRP-152 rat prostatic epithelial cells.
Topics: Androgen Antagonists; Androgens; Animals; Antibodies; Cell Division; Cell Line; Dihydrotestosterone; Down-Regulation; Finasteride; Flutamide; Male; Prostate; Rats; Testosterone; Transforming Growth Factor beta | 1998 |
Effects of gonadal steroids and their antagonists on DNA synthesis in human vascular cells.
Topics: Analysis of Variance; Androgen Antagonists; Antibodies, Monoclonal; Cell Division; Cell Line; Cells, Cultured; Creatine Kinase; Dihydrotestosterone; DNA; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Flutamide; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Piperidines; Platelet-Derived Growth Factor; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Thymidine | 1998 |
Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat.
Topics: Androgen Antagonists; Animals; Benzopyrans; Bone Density; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Female; Femur; Flutamide; Medroxyprogesterone Acetate; Ovariectomy; Progesterone Congeners; Propionates; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 1998 |
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Antineoplastic Agents, Hormonal; Carcinoma, Hepatocellular; DDT; Dihydrotestosterone; Estradiol; Flutamide; Humans; Insecticides; Isomerism; Methoxychlor; Progesterone; Receptors, Androgen; Testosterone; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Direct actions of gonadal steroid hormones on FSH secretion and expression in the infantile female rat.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gene Expression Regulation; Gonadal Steroid Hormones; Gonadotropins; Luteinizing Hormone; Microscopy; Pituitary Gland; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroids; Tamoxifen | 1998 |
IL-6 expression by oral fibroblasts is regulated by androgen.
Topics: Androgen Antagonists; Cells, Cultured; Cyproterone Acetate; Dihydrotestosterone; Fibroblasts; Flutamide; Gene Expression Regulation; Gingiva; Humans; Interleukin-6 | 1998 |
Effects of gonadal and adrenal androgens in a novel androgen-responsive human osteoblastic cell line.
Topics: Adrenal Glands; Aged; Alkaline Phosphatase; Androgen Antagonists; Androgens; Cell Division; Cell Line; Collagen; Dehydroepiandrosterone; Dihydrotestosterone; DNA-Binding Proteins; Early Growth Response Transcription Factors; Flutamide; Gene Expression Regulation; Humans; Kruppel-Like Transcription Factors; Male; Osteoblasts; Osteocalcin; Testosterone; Transcription Factors; Transforming Growth Factor beta | 1998 |
Functional characterization of mutant androgen receptors from androgen-independent prostate cancer.
Topics: Amino Acid Substitution; Androgen Antagonists; Androgens; Androstenedione; Animals; beta-Galactosidase; Cell Line; Dihydrotestosterone; Estradiol; Flutamide; Genes, Reporter; Imidazoles; Imidazolidines; Luciferases; Male; Point Mutation; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Recombinant Fusion Proteins; Transfection | 1997 |
Evidence for androgen receptor gene expression and growth inhibitory effect of dihydrotestosterone on human adrenocortical cells.
Topics: Adrenal Cortex; Androgen Antagonists; Cell Division; Cells, Cultured; Cyproterone Acetate; Dihydrotestosterone; Female; Flutamide; Gene Expression; Humans; Immunohistochemistry; Male; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 1998 |
Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells.
Topics: Androgen Antagonists; Androgens; Breast Neoplasms; Caspase 3; Caspases; Dihydrotestosterone; Down-Regulation; Estradiol; Estrogens; Female; Flutamide; Humans; Immunohistochemistry; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1999 |
Androgens regulate bone resorption activity of isolated osteoclasts in vitro.
Topics: Acid Phosphatase; Androgen Antagonists; Androgens; Animals; Bone Resorption; Cathepsin B; Chickens; Dihydrotestosterone; Flutamide; Genes, Reporter; Humans; Isoenzymes; Metribolone; Mice; Osteoclasts; Receptors, Androgen; Regulatory Sequences, Nucleic Acid; Tartrate-Resistant Acid Phosphatase; Transfection; Transforming Growth Factor beta | 1999 |
Synergistic activation of yeast-expressed rat androgen receptor by modulators of protein kinase-A.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Androgens; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyproterone; Dihydrotestosterone; Enzyme Inhibitors; Flutamide; Gene Expression Regulation; Genes, Reporter; Metribolone; Okadaic Acid; Rats; Receptors, Androgen; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Saccharomyces cerevisiae; Signal Transduction; Transcriptional Activation; Transformation, Genetic | 1999 |
Brain androgen-inducible aromatase is critical for adolescent organization of environment-specific social interaction in male rats.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Adaptation, Physiological; Adaptation, Psychological; Androgen Antagonists; Animals; Aromatase; Aromatase Inhibitors; Body Weight; Brain; Brain Chemistry; Dihydrotestosterone; Enzyme Inhibitors; Fadrozole; Finasteride; Flutamide; Male; Organ Size; Prostate; Rats; Rats, Long-Evans; Receptors, Androgen; Sexual Maturation; Social Dominance; Testosterone | 1999 |
Phosphorylation/dephosphorylation of androgen receptor as a determinant of androgen agonistic or antagonistic activity.
Topics: Androgen Antagonists; Androgens; Anilides; Animals; Base Sequence; Dihydrotestosterone; Estradiol; Estramustine; Flutamide; Humans; Ligands; Male; Molecular Sequence Data; Nitriles; Phosphorylation; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured | 1999 |
Androgens modulate interleukin-6 production by gingival fibroblasts in vitro.
Topics: Androgen Antagonists; Androgens; Cells, Cultured; Culture Media, Conditioned; Dihydrotestosterone; DNA; Down-Regulation; Female; Fibroblasts; Flutamide; Gingiva; Gingivitis; Humans; Interleukin-6; Male; Pregnancy; Pregnancy Complications; Puberty; Reverse Transcriptase Polymerase Chain Reaction; Testosterone | 1999 |
Regulation of GCDFP-15 expression in human mammary cancer cells.
Topics: Androgen Antagonists; Anilides; Apolipoproteins; Apolipoproteins D; Breast Neoplasms; Carrier Proteins; Cell Division; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured | 1999 |
Estrogen, but not androgens, regulates androgen receptor messenger ribonucleic acid expression in the developing male rat forebrain.
Topics: Aging; Androgens; Animals; Animals, Newborn; Diethylstilbestrol; Dihydrotestosterone; Female; Flutamide; Gene Expression Regulation, Developmental; In Situ Hybridization; Male; Orchiectomy; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Sex Characteristics; Testosterone; Transcription, Genetic | 1999 |
The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Cell Line; Dihydrotestosterone; Flutamide; Humans; Interleukin-1; Interleukin-6; NF-kappa B; Osteoblasts; Paracrine Communication; Protein Binding; RNA, Messenger; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 1999 |
Androgen and epidermal growth factor down-regulate cyclin-dependent kinase inhibitor p27Kip1 and costimulate proliferation of MDA PCa 2a and MDA PCa 2b prostate cancer cells.
Topics: Androgen Antagonists; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cycloheximide; Dihydrotestosterone; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flutamide; Humans; Male; Metribolone; Microtubule-Associated Proteins; Prostatic Neoplasms; Protein Synthesis Inhibitors; Receptors, Androgen; Testosterone Congeners; Trastuzumab; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1999 |
Combined treatment with the 5 alpha-reductase inhibitor PNU 157706 and the antiandrogen flutamide on the Dunning R3327 prostatic carcinoma in rats.
Topics: Androstenes; Animals; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Enzyme Inhibitors; Flutamide; Male; Organ Size; Prostate; Prostatic Neoplasms; Rats; Testosterone | 1999 |
Effects of androgens and antiandrogens on the quantitative immunohistochemistry of gonadotrope cells in prepubertal male rats.
Topics: Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Flutamide; Follicle Stimulating Hormone; Immunohistochemistry; Luteinizing Hormone; Male; Nitriles; Orchiectomy; Pituitary Gland; Rats; Rats, Sprague-Dawley; Sexual Maturation; Tosyl Compounds | 1999 |
Neural androgen receptor regulation: effects of androgen and antiandrogen.
Topics: Androgen Antagonists; Animals; Brain; Dihydrotestosterone; Female; Flutamide; Kinetics; Male; Mice; Neurons; Orchiectomy; Receptors, Androgen; Testosterone; Up-Regulation | 1999 |
Androgens rescue avian embryonic lumbar spinal motoneurons from injury-induced but not naturally occurring cell death.
Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Axotomy; Cell Death; Cell Division; Cell Survival; Chick Embryo; Dihydrotestosterone; Flutamide; Lumbosacral Region; Motor Neurons; Receptors, Androgen; Spinal Cord; Testosterone | 1999 |
Androgen receptor expression is greater in macrophages from male than from female donors. A sex difference with implications for atherogenesis.
Topics: Adult; Aged; Arteriosclerosis; Cholesterol Esters; Dihydrotestosterone; Female; Flutamide; Humans; Macrophages; Male; Middle Aged; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors | 2000 |
Examination of selected food additives and organochlorine food contaminants for androgenic activity in vitro.
Topics: Adenocarcinoma; Androgens; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Survival; Chlordecone; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Food Additives; Food Contamination; Hexachlorocyclohexane; Hormone Antagonists; Humans; Insecticides; Luciferases; Male; Pesticide Residues; Polychlorinated Dibenzodioxins; Prostatic Neoplasms; Receptors, Androgen; Toxaphene; Transfection; Tumor Cells, Cultured | 2000 |
Down-regulation of transforming growth factor beta receptors by androgen in ovarian cancer cells.
Topics: Dihydrotestosterone; Down-Regulation; Female; Flutamide; Gene Expression Regulation; Humans; Ovarian Neoplasms; Receptors, Androgen; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured | 2000 |
Effects of androgens, progesterone and their antagonists on the developmental competence of in vitro matured bovine oocytes.
Topics: Activins; Analysis of Variance; Androgen Antagonists; Androgens; Animals; Cattle; Cleavage Stage, Ovum; Dihydrotestosterone; Female; Fertilization in Vitro; Flutamide; Follistatin; Glycoproteins; Hormone Antagonists; Inhibins; Mifepristone; Peptides; Progesterone; Testosterone | 2000 |
Rapid androgen actions on calcium signaling in rat sertoli cells and two human prostatic cell lines: similar biphasic responses between 1 picomolar and 100 nanomolar concentrations.
Topics: Androgen Antagonists; Androgens; Animals; Calcium Signaling; Cell Line; Cyproterone Acetate; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gap Junctions; Humans; Kinetics; Male; Metribolone; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Sertoli Cells; Testosterone; Tumor Cells, Cultured | 2000 |
Effects of in utero exposure to linuron on androgen-dependent reproductive development in the male Crl:CD(SD)BR rat.
Topics: Androgens; Animals; Animals, Newborn; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Genitalia, Male; Herbicides; Humans; Linuron; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Transfection; Tumor Cells, Cultured | 2000 |
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females.
Topics: Androgen Antagonists; Androstenedione; Animals; Antibodies; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flutamide; Fulvestrant; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Stress, Mechanical; Tamoxifen; Testosterone; Thymidine | 2000 |
Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Animals; Binding Sites; Cell Line; COS Cells; Dihydrotestosterone; DNA; Estradiol; Flutamide; Humans; Male; Mice; Mice, Transgenic; Models, Molecular; Mutagenesis; Mutation; Progesterone; Prostatic Neoplasms; Protein Structure, Secondary; Receptors, Androgen; Structure-Activity Relationship; Transcriptional Activation; Transfection | 2001 |
The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.
Topics: Androgen Antagonists; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Flutamide; Liver; Male; Microsomes, Liver; Oncorhynchus mykiss; Receptors, Androgen; Sex Factors; Vitellogenins | 2000 |
Characterization of androgen receptors in a well-differentiated endometrial adenocarcinoma cell line (Ishikawa).
Topics: Adenocarcinoma; Alkaline Phosphatase; Androgens; Cell Differentiation; Cell Nucleus; Diethylstilbestrol; Dihydrotestosterone; Endometrial Neoplasms; Endometrium; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Flutamide; Fulvestrant; Humans; Metribolone; Progesterone; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2000 |
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor.
Topics: Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Cell Division; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flutamide; Fulvestrant; Glucuronates; Mice; Mice, Inbred ICR; Osteoclasts; Parathyroid Hormone; Receptors, Androgen; Teriparatide; Testosterone | 2001 |
Androgen and estrogen stimulation of ornithine decarboxylase activity in mouse kidney.
Topics: Androgen Antagonists; Animals; Cyproterone Acetate; Dichlorodiphenyl Dichloroethylene; Dihydrotestosterone; Estradiol; Female; Flutamide; Kidney; Mice; Mice, Inbred CBA; Ornithine Decarboxylase; Oxazoles; Spironolactone; Testosterone | 2000 |
Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents, Hormonal; Carcinoma; Dihydrotestosterone; DNA-Binding Proteins; Drug Synergism; Flutamide; Gene Expression; Humans; Interleukin-6; Kidney Neoplasms; Male; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
Initial induction and subsequent reduction of alpha(2u)-globulin in urine and serum of mature male rats after repeated intraperitoneal injections of (anti)estrogen.
Topics: Alpha-Globulins; Animals; Benzhydryl Compounds; DDT; Dieldrin; Diethylstilbestrol; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogen Antagonists; Flutamide; Genistein; Injections, Intraperitoneal; Isoflavones; Liver; Male; Organ Size; Oxidation-Reduction; Phenols; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tamoxifen; Testis | 2001 |
Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats.
Topics: Androgen Antagonists; Anilides; Animals; Dihydrotestosterone; Flutamide; Follicle Stimulating Hormone; Hormone Replacement Therapy; Immunohistochemistry; Luteinizing Hormone; Male; Microscopy, Electron; Nitriles; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Secretory Vesicles; Sexual Maturation; Tosyl Compounds | 2001 |
The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Animals; Cell Nucleus; COS Cells; Dihydrotestosterone; Euchromatin; Flutamide; Green Fluorescent Proteins; Heterochromatin; Humans; Ligands; Luminescent Proteins; Microscopy, Confocal; Plasmids; Point Mutation; Progesterone; Protein Binding; Receptors, Androgen; Receptors, Progesterone; Recombinant Fusion Proteins; Transcription, Genetic; Transcriptional Activation | 2001 |
Contribution of androgens to chronic allograft nephropathy is mediated by dihydrotestosterone.
Topics: Androgen Antagonists; Animals; Chronic Disease; Dihydrotestosterone; Female; Flutamide; Kidney Diseases; Kidney Transplantation; Male; Rats; Rats, Inbred F344; Sex Factors; Transplantation, Homologous | 2001 |
Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.
Topics: Adenoviridae; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Cell Line; Dexamethasone; Dihydrotestosterone; Flutamide; Gene Expression; Glucocorticoids; Humans; Luciferases; Mammary Tumor Virus, Mouse; Pesticides; Progesterone; Promoter Regions, Genetic; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Recombinant Fusion Proteins; Transduction, Genetic; Transfection; Tumor Cells, Cultured | 2002 |
The regulation of HSL and LPL expression by DHT and flutamide in human subcutaneous adipose tissue.
Topics: Adipocytes; Adipose Tissue; Cells, Cultured; Dihydrotestosterone; Female; Flutamide; Humans; Lipoprotein Lipase; Middle Aged; Receptors, Androgen; Sterol Esterase | 2002 |
Stabilization of androgen receptor protein is induced by agonist, not by antagonists.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Animals; Blotting, Northern; Blotting, Western; CHO Cells; Cricetinae; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Humans; Ligands; Luciferases; Nitriles; Plasmids; Receptors, Androgen; RNA Processing, Post-Transcriptional; Time Factors; Tosyl Compounds; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Androgens protect against apolipoprotein E4-induced cognitive deficits.
Topics: Androgen Antagonists; Androgens; Animals; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Brain; Cognition; Cognition Disorders; Dihydrotestosterone; Female; Flutamide; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Receptors, Androgen; Recognition, Psychology; Sex Factors; Testosterone | 2002 |
Ovarian hormones after postnatal day 20 reduce neuron number in the rat primary visual cortex.
Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Cell Count; Dihydrotestosterone; Female; Flutamide; Gonadal Steroid Hormones; Male; Neurons; Orchiectomy; Ovariectomy; Rats; Rats, Long-Evans; Sex Differentiation; Testosterone; Visual Cortex | 2002 |
Nerve growth factor induces the re-expression of functional androgen receptors and p75(NGFR) in the androgen-insensitive prostate cancer cell line DU145.
Topics: Androgen Antagonists; Androgens; Apoptosis; Cell Division; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Gene Expression; Humans; Male; Nerve Growth Factor; Prostatic Neoplasms; Receptor, Nerve Growth Factor; Receptors, Androgen; RNA, Messenger; Telomerase; Tumor Cells, Cultured | 2002 |
Sexual dimorphism in the spontaneous recovery from spinal cord injury: a gender gap in beneficial autoimmunity?
Topics: Androgen Antagonists; Animals; Autoimmunity; Castration; Dihydrotestosterone; Female; Flutamide; Locomotion; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Rats; Rats, Sprague-Dawley; Recovery of Function; Sex Factors; Spinal Cord Injuries | 2002 |
Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgen Antagonists; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Immune Sera; Immunization; Isoenzymes; Luteinizing Hormone; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Recombinant Proteins; RNA, Messenger; Testis; Testosterone | 2003 |
Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
Topics: Androgens; Blotting, Western; Cell Line, Tumor; Chromones; Culture Media, Conditioned; Dihydrotestosterone; DNA-Binding Proteins; Enzyme Inhibitors; Flutamide; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Ligands; Male; Models, Biological; Morpholines; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; RNA; Signal Transduction; Time Factors; Transcription Factors; Transcriptional Activation; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.
Topics: Animals; Cloning, Molecular; COS Cells; Dihydrotestosterone; Flutamide; Gelsolin; Humans; Male; Mice; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation | 2003 |
Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.
Topics: Androgen Antagonists; Anilides; Autocrine Communication; BCG Vaccine; Carcinoma, Transitional Cell; Dihydrotestosterone; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Genes, Reporter; Humans; Neoplasms, Hormone-Dependent; NF-kappa B; Nitriles; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tosyl Compounds; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vaccines, Attenuated | 2003 |
Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.
Topics: 5-alpha Reductase Inhibitors; Adrenergic alpha-Antagonists; Androgen Antagonists; Anilides; Animals; Capillaries; Chlormadinone Acetate; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Hormone Antagonists; Male; Microcirculation; Nitriles; Prazosin; Prostate; Rats; Rats, Wistar; Sulfonamides; Tamsulosin; Testosterone; Tosyl Compounds | 2003 |
Feedback inhibition of steroidogenic acute regulatory protein expression in vitro and in vivo by androgens.
Topics: Androgen Antagonists; Androgens; Animals; Anti-Mullerian Hormone; Cell Line, Tumor; Dihydrotestosterone; Feedback, Physiological; Flutamide; Gene Expression; Glycoproteins; Hypophysectomy; In Vitro Techniques; Leydig Cell Tumor; Male; Mice; Mice, Inbred Strains; Phosphoproteins; RNA, Messenger; Testicular Hormones; Testosterone; Transcription, Genetic | 2004 |
Estrogen and androgen regulation of plasma membrane calcium pump activity in immortalized distal tubule kidney cells.
Topics: Androgen Antagonists; Animals; Calcium; Calcium-Transporting ATPases; Cation Transport Proteins; Cattle; Cells, Cultured; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Estrogens; Female; Flutamide; Kidney Tubules, Distal; Male; Plasma Membrane Calcium-Transporting ATPases; Polyunsaturated Alkamides | 2003 |
Effect of dihydrotestosterone on pituitary follicle-stimulating hormone isoforms in adult male rats treated with a gonadotropin-releasing hormone antagonist.
Topics: Androgen Antagonists; Animals; Castration; Dihydrotestosterone; Drug Interactions; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Male; Pituitary Gland; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, LHRH | 2003 |
The effects of combined aromatase inhibitor and anti-androgen on male territorial aggression in a tropical population of rufous-collared sparrows, Zonotrichia capensis.
Topics: Aggression; Androgen Antagonists; Androstatrienes; Animals; Aromatase Inhibitors; Corticosterone; Dihydrotestosterone; Flutamide; Male; Songbirds; Territoriality; Testosterone | 2004 |
Interactions between androgen and growth factors in granulosa cell subtypes of porcine antral follicles.
Topics: Androgen Antagonists; Androgens; Animals; Cell Division; Dihydrotestosterone; DNA; Drug Combinations; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Growth Substances; Insulin-Like Growth Factor I; Progesterone; Swine; Time Factors | 2004 |
Evidence that inhibited prostatic epithelial bud formation in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed C57BL/6J fetal mice is not due to interruption of androgen signaling in the urogenital sinus.
Topics: Androgen Antagonists; Animals; Cells, Cultured; Dihydrotestosterone; Environmental Pollutants; Epithelium; Female; Fetus; Flutamide; Gene Expression Regulation, Developmental; Luciferases; Male; Maternal Exposure; Mesoderm; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Prostate; Receptors, Androgen; Testis; Testosterone; Urogenital System | 2004 |
Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions.
Topics: Adipose Tissue; Androgen Antagonists; Androgens; Animals; Apolipoproteins B; Body Composition; Dihydrotestosterone; Drug Administration Schedule; Flutamide; Hypogonadism; Lipoproteins; Lipoproteins, LDL; Macaca fascicularis; Male; Mesentery; Orchiectomy; Testosterone | 2004 |
Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse.
Topics: Androgen Antagonists; Animals; Corticosterone; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Flutamide; Hypothalamo-Hypophyseal System; Male; Mice; Orchiectomy; Pituitary-Adrenal System; Receptors, Estrogen; Restraint, Physical; Stress, Psychological; Tamoxifen | 2004 |
Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Animals; Aromatase Inhibitors; Biological Assay; Biomarkers; Cyprinidae; Dihydrotestosterone; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Monitoring; Fadrozole; Female; Flutamide; Gonads; Male; Sex Factors; Sexual Development; Vitellogenins; Water Pollutants, Chemical | 2004 |
5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Calcitriol; Cycloheximide; Cytochrome P-450 Enzyme System; Dihydrotestosterone; Drug Interactions; Flutamide; Gene Expression Regulation, Enzymologic; Humans; Male; Nitriles; Prostatic Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Tosyl Compounds; Tumor Cells, Cultured; Vitamin D3 24-Hydroxylase | 2005 |
Evaluation of the model anti-androgen flutamide for assessing the mechanistic basis of responses to an androgen in the fathead minnow (Pimephales promelas).
Topics: Androgen Antagonists; Animals; Binding, Competitive; Cyprinidae; Dihydrotestosterone; Dose-Response Relationship, Drug; Environmental Exposure; Evaluation Studies as Topic; Flutamide; Models, Biological; Receptors, Androgen; Sex Differentiation; Time Factors; Trenbolone Acetate; Vitellogenins | 2004 |
Androgen-regulated transcripts in the neonatal mouse testis as determined through microarray analysis.
Topics: Androgen Antagonists; Androgens; Animals; Animals, Newborn; Biomarkers; Cell Differentiation; Cell Division; Cells, Cultured; Dihydrotestosterone; Flutamide; Gene Expression; Male; Mice; Oligonucleotide Array Sequence Analysis; Receptors, Androgen; RNA, Messenger; Sertoli Cells; Testis; Testosterone Propionate | 2005 |
Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels.
Topics: Androgen Antagonists; Androgens; Androstenediol; Androsterone; Calcium Channels, L-Type; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Myometrium; Pregnancy; Protein Synthesis Inhibitors; Statistics, Nonparametric; Testosterone; Uterine Contraction | 2005 |
Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; comparison of gene expression between the blood-brain and -retinal barriers.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Brain; Cell Line; Dihydrotestosterone; Endothelial Cells; Female; Flutamide; Gene Expression; Gene Expression Regulation; Male; Organic Anion Transporters, Sodium-Independent; Rats; Receptors, Androgen; RNA, Messenger; Sex Characteristics | 2005 |
Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease.
Topics: Androgen Antagonists; Animals; Cell Proliferation; Dihydrotestosterone; Disease Models, Animal; Disease Progression; eIF-2 Kinase; Female; Flutamide; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Polycystic Kidney, Autosomal Dominant; Proto-Oncogene Proteins B-raf; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sex Factors; Signal Transduction; Testosterone Congeners | 2005 |
The partial female to male sex reversal in Wnt-4-deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action.
Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Animals; Cholesterol Side-Chain Cleavage Enzyme; Dihydrotestosterone; Disorders of Sex Development; Endothelial Cells; Estradiol; Female; Flutamide; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Ovary; Pregnancy; Proto-Oncogene Proteins; Sex Characteristics; Signal Transduction; Steroid 17-alpha-Hydroxylase; Testosterone; Wnt Proteins; Wnt4 Protein; Wolffian Ducts | 2005 |
Androgens augment the mitogenic effects of oocyte-secreted factors and growth differentiation factor 9 on porcine granulosa cells.
Topics: Androgen Antagonists; Androgens; Animals; Bone Morphogenetic Protein 15; Cell Proliferation; Cells, Cultured; Coculture Techniques; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Growth Differentiation Factor 9; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Mice; Mitogens; Oocytes; Progesterone; Recombinant Proteins; Swine; Testosterone | 2005 |
Mechanism of androgen-induced thymic atrophy in the wall lizard, Hemidactylus flaviviridis: an in vitro study.
Topics: Androgen Antagonists; Androgens; Animals; Apoptosis; Caspases; Cell Proliferation; Cycloheximide; Dactinomycin; Dihydrotestosterone; Flutamide; In Vitro Techniques; Lizards; Male; Protein Synthesis Inhibitors; Thymus Gland | 2005 |
Androgen-induced yawning in rhesus monkey females is reversed with a nonsteroidal anti-androgen.
Topics: Androgen Antagonists; Androgens; Animals; Dihydrotestosterone; Female; Flutamide; Macaca mulatta; Male; Sex Characteristics; Yawning | 2006 |
Acquisition of androgen independence by human prostate epithelial cells during arsenic-induced malignant transformation.
Topics: Androgen Antagonists; Androgens; Animals; Arsenic; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Dihydrotestosterone; Epidermal Growth Factor; Epithelial Cells; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Flutamide; Gene Expression Regulation; Humans; Male; Mice; Pituitary Gland; Prostate; Prostatic Neoplasms; Receptors, Androgen; RNA, Messenger | 2005 |
Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1.
Topics: Abdominal Injuries; Animals; Aromatase; Dihydrotestosterone; Electron Transport Complex IV; Estradiol; Estrogen Antagonists; Flutamide; Fulvestrant; Heart Function Tests; Hemorrhage; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Testosterone; Transcription Factors; Up-Regulation | 2006 |
Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro.
Topics: Androgen Antagonists; Androgens; Animals; Benzhydryl Compounds; Cell Line; Dihydrotestosterone; Endocrine Disruptors; Estrogens, Non-Steroidal; Flutamide; Lethal Dose 50; Mutagenicity Tests; Phenols; Plasmids; Receptors, Androgen; Transcription, Genetic | 2005 |
DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.
Topics: Androgen Antagonists; Anilides; Cell Proliferation; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Flutamide; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 5; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Middle Aged; Nitriles; Prostate; Receptor, IGF Type 1; Stromal Cells; Testosterone; Tosyl Compounds | 2006 |
Androgen effects on hippocampal CA1 spine synapse numbers are retained in Tfm male rats with defective androgen receptors.
Topics: Androgens; Animals; Dendrites; Dendritic Cells; Dihydrotestosterone; Estradiol; Flutamide; Genotype; Hippocampus; Male; Microscopy, Electron; Models, Statistical; Mutation; Neurons; Orchiectomy; Rats; Receptors, Androgen; Sesame Oil; Synapses; Time Factors | 2006 |
The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.
Topics: Androgen Antagonists; Androgens; Androstane-3,17-diol; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Flutamide; Hypothalamo-Hypophyseal System; Immobilization; Male; Neurons; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Stress, Physiological; Tamoxifen | 2006 |
[Effect of dihydrotestosterone on the transcriptions and expressions of Smad3 and Smad4 in LNCaP cell line].
Topics: Androgens; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad3 Protein; Smad4 Protein; Transcription, Genetic | 2006 |
Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Anxiety; Dihydrotestosterone; Drug Implants; Flutamide; Hippocampus; Hormone Replacement Therapy; Male; Orchiectomy; Rats; Rats, Long-Evans | 2006 |
Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens.
Topics: Angiogenesis Inhibitors; Animals; Dihydrotestosterone; Environmental Exposure; Ethinyl Estradiol; Female; Fish Proteins; Flutamide; Kidney; Male; Methyltestosterone; Models, Animal; Osmolar Concentration; Seasons; Smegmamorpha | 2006 |
Development of a stickleback kidney cell culture assay for the screening of androgenic and anti-androgenic endocrine disrupters.
Topics: Anabolic Agents; Androgen Antagonists; Androgens; Animals; Cells, Cultured; Dihydrotestosterone; Female; Fish Proteins; Flutamide; Gene Expression; Kidney; Male; Smegmamorpha; Testosterone; Time Factors; Toxicity Tests; Trenbolone Acetate | 2006 |
Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay.
Topics: Androgen Antagonists; Animals; Cell Line; Cell Proliferation; Cell Survival; Dexamethasone; Dihydrotestosterone; Flutamide; Humans; Imidazolidines; Luciferases; Molecular Structure; Nitriles; Permethrin; Pesticides; Pyrethrins; Receptors, Androgen; Recombinant Fusion Proteins; Response Elements; Transfection | 2007 |
Effect of bisphenol A, tetrachlorobisphenol A and pentachlorophenol on the transcriptional activities of androgen receptor-mediated reporter gene.
Topics: Androgen Antagonists; Androgens; Animals; Benzhydryl Compounds; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Chlorophenols; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Combinations; Flutamide; Genes, Reporter; Pentachlorophenol; Phenols; Receptors, Androgen; Transcription, Genetic | 2006 |
Estrogen-induced upregulation of AR expression and enhancement of AR nuclear translocation in mouse fallopian tubes in vivo.
Topics: Animals; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Diethylstilbestrol; Dihydrotestosterone; Estrogens; Fallopian Tubes; Female; Flutamide; Gonadotropins; Granulosa Cells; Male; Mice; Mice, Inbred C57BL; Protein Transport; Receptors, Androgen; Up-Regulation | 2007 |
Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells.
Topics: Androgen Antagonists; Androgens; Cadmium; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Progression; Epithelial Cells; Estradiol; Estrogens; Flutamide; Gene Expression Regulation; Humans; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger; Signal Transduction | 2007 |
Endocrine disrupters with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: I. Effects on sex steroid levels and biomarker expression.
Topics: Androgen Antagonists; Androgens; Animals; Biomarkers; Dihydrotestosterone; Endocrine Disruptors; Estradiol; Estrogen Antagonists; Estrogens; Ethinyl Estradiol; Female; Flutamide; Italy; Male; Prealbumin; Retinol-Binding Proteins; Retinol-Binding Proteins, Plasma; Rivers; RNA, Messenger; Tamoxifen; Testosterone; Transferrin; Vitellogenins; Water Pollutants, Chemical; Xenopus laevis | 2007 |
Ligand-specific dynamics of the androgen receptor at its response element in living cells.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Animals; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cyproterone Acetate; Dihydrotestosterone; Female; Fluorescence Recovery After Photobleaching; Flutamide; Genes, Reporter; Green Fluorescent Proteins; In Situ Hybridization, Fluorescence; Ligands; Luciferases; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Metribolone; Mice; Microscopy, Video; Mifepristone; Models, Biological; Nitriles; Plasmids; Promoter Regions, Genetic; Receptors, Androgen; Response Elements; Testosterone; Tosyl Compounds; Transcription, Genetic | 2007 |
The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.
Topics: Amino Acid Sequence; Amino Acid Substitution; Androgen Antagonists; Anilides; Animals; Cyproterone Acetate; Dihydrotestosterone; Fluoresceins; Fluorescence Resonance Energy Transfer; Flutamide; Ligands; Mifepristone; Nitriles; Oligopeptides; Rats; Receptors, Androgen; Tosyl Compounds | 2007 |
Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression.
Topics: Androgens; Anilides; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Flutamide; HeLa Cells; Humans; Male; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Receptors, Interferon; Tosyl Compounds; Transcriptional Activation | 2007 |
Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells.
Topics: Androgen Antagonists; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Chromatin Immunoprecipitation; Dihydrotestosterone; DNA-Binding Proteins; Flow Cytometry; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice; Mice, Nude; Proteins; Receptors, Androgen; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Small Interfering; Telomerase; Transfection; Tumor Cells, Cultured | 2007 |
Dihydrotestosterone inhibits tumor necrosis factor alpha induced interleukin-1alpha mRNA expression in rheumatoid fibroblast-like synovial cells.
Topics: Androgen Receptor Antagonists; Arthritis, Rheumatoid; Cell Culture Techniques; Cell Line, Transformed; Cells, Cultured; Dihydrotestosterone; Flutamide; Genes, Reporter; Humans; Interleukin-1alpha; Luciferases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Synovial Membrane; Time Factors; Transfection; Tumor Necrosis Factor-alpha | 2007 |
Androgen receptor blockade in experimental combination therapy of pancreatic cancer.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Bevacizumab; Cell Division; Cell Line, Tumor; Deoxycytidine; Dihydrotestosterone; Drug Therapy, Combination; Flutamide; Gemcitabine; Humans; Immunohistochemistry; Mice; Mice, Nude; Pancreatic Neoplasms; Receptors, Androgen; Testosterone; Xenograft Model Antitumor Assays | 2007 |
Reciprocal regulation of 5alpha-dihydrotestosterone, interleukin-6 and interleukin-8 during proliferation of epithelial ovarian carcinoma.
Topics: Androgen Receptor Antagonists; Carcinoma; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Enzyme Inhibitors; Epithelial Cells; Female; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Interleukin-8; Ovarian Neoplasms; Promoter Regions, Genetic | 2007 |
A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Antineoplastic Agents; Cell Proliferation; Dihydrotestosterone; Drug Resistance, Neoplasm; Drug Synergism; Flutamide; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Imidazolidines; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Tosyl Compounds; Transcription, Genetic | 2007 |
The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Biomarkers, Tumor; Dihydrotestosterone; Disease Progression; Flutamide; Goserelin; Humans; Leuprolide; Male; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Orchiectomy; Prognosis; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone | 2007 |
Activation of the androgen receptor alters the intracellular calcium response to glutamate in primary hippocampal neurons and modulates sarco/endoplasmic reticulum calcium ATPase 2 transcription.
Topics: Androgen Antagonists; Androgens; Animals; Calcium; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Flutamide; Gene Expression Regulation; Glutamic Acid; Hippocampus; Neurons; Pregnancy; Rats; Receptors, Androgen; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Time Factors | 2007 |
Androgen manipulation alters oxidative DNA adduct levels in androgen-sensitive prostate cancer cells grown in vitro and in vivo.
Topics: Androgens; Animals; Cell Line, Tumor; Dihydrotestosterone; DNA Adducts; DNA Damage; Flutamide; Humans; Male; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Reactive Oxygen Species | 2008 |
Anabolic androgens restore mating after sexual satiety in male rats.
Topics: Anabolic Agents; Androgens; Animals; Dihydrotestosterone; Ejaculation; Estradiol; Female; Flutamide; gamma-Aminobutyric Acid; Male; Nandrolone; Nandrolone Decanoate; Rats; Rats, Wistar; Receptors, Estrogen; Sexual Behavior, Animal; Tamoxifen; Testosterone | 2008 |
Androgen-regulated cervical ripening: a structural, biomechanical, and molecular analysis.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Animals; Biomechanical Phenomena; Cervical Ripening; Cervix Uteri; Collagen; Dihydrotestosterone; Female; Flutamide; Gestational Age; Hyaluronic Acid; Immunohistochemistry; Matrix Metalloproteinase 2; Microscopy, Polarization; Pregnancy; Proteoglycans; Rats; Rats, Sprague-Dawley; Receptors, Androgen | 2008 |
Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Animals; Animals, Newborn; Brain Damage, Chronic; Calcium; Cells, Cultured; Dihydrotestosterone; Disease Models, Animal; Drug Interactions; Female; Flutamide; GABA Agents; Genetic Predisposition to Disease; Hippocampus; In Situ Nick-End Labeling; Male; Neurons; Rats; Receptors, GABA-A; Sex Characteristics | 2008 |
Effect of dihydrotestosterone on hydrogen peroxide-induced apoptosis of mouse embryonic stem cells.
Topics: Androgen Antagonists; Animals; Antioxidants; Apoptosis; Caspase 3; Catalase; Dihydrotestosterone; DNA Fragmentation; Embryonic Stem Cells; Enzyme Activation; Flutamide; Hydrogen Peroxide; Inhibitor of Apoptosis Proteins; Lipid Peroxides; Mice; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Androgen | 2008 |
Characterization of androgen regulation of ZEB-1 and PSA in 22RV1 prostate cancer cells.
Topics: Androgen Antagonists; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Tumor Cells, Cultured; Zinc Finger E-box-Binding Homeobox 1 | 2008 |
5Alpha-dihydrotestosterone up-regulates transthyretin levels in mice and rat choroid plexus via an androgen receptor independent pathway.
Topics: Age Factors; Analysis of Variance; Androgen Receptor Antagonists; Androgens; Animals; Animals, Newborn; Anthropology, Cultural; Choroid Plexus; Dihydrotestosterone; Dose-Response Relationship, Drug; Epithelial Cells; Flutamide; Humans; Male; Mice; Mice, Transgenic; Prealbumin; Rats; Rats, Wistar; Receptors, Androgen; Signal Transduction; Time Factors; Up-Regulation | 2008 |
Effects of androgens on serum concentrations of gonadotropins and ovarian steroids in gilts.
Topics: Androgen Antagonists; Androgens; Animals; Dihydrotestosterone; Estradiol; Estrous Cycle; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropins; Ovary; Ovulation; Steroids; Swine; Testosterone | 2008 |
Androgen regulation of corticotropin-releasing hormone receptor 2 (CRHR2) mRNA expression and receptor binding in the rat brain.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Animals; Autoradiography; Cells, Cultured; Dihydrotestosterone; Female; Flutamide; Gene Expression Regulation, Developmental; Hippocampus; Hypothalamus; Male; Neurons; Orchiectomy; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Septal Nuclei | 2008 |
Mechanisms involved in testosterone-induced vasodilatation in pig prostatic small arteries.
Topics: Androgen Antagonists; Androgens; Animals; Arteries; Calcium Channel Blockers; Dihydrotestosterone; Dose-Response Relationship, Drug; Endothelium, Vascular; Flutamide; Male; Potassium; Potassium Channel Blockers; Prostate; Regional Blood Flow; Swine; Testosterone; Vasodilation | 2008 |
Suppression of mutant androgen receptors by flutamide.
Topics: Androgen Antagonists; Androgens; Binding, Competitive; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Luciferases; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Transcriptional Activation | 2009 |
Androgenic regulation of ventral epithelial bud number and pattern in mouse urogenital sinus.
Topics: Androgen Antagonists; Androgen-Insensitivity Syndrome; Androgens; Animals; Animals, Newborn; Body Patterning; Dihydrotestosterone; Female; Fetus; Flutamide; Homeodomain Proteins; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Organ Culture Techniques; Polychlorinated Dibenzodioxins; Prostate; Receptors, Androgen; Sex Characteristics; Signal Transduction; Teratogens; Terminology as Topic; Transcription Factors; Urethra | 2010 |
Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.
Topics: Androgen Antagonists; Anilides; Blotting, Western; Cell Line, Tumor; Cyproterone Acetate; Dihydrotestosterone; Flutamide; Humans; Hydrocortisone; Hydrophobic and Hydrophilic Interactions; Male; Mutation; Nitriles; Progesterone; Prostatic Neoplasms; Protein Structure, Secondary; Receptors, Androgen; Steroids; Structure-Activity Relationship; Tosyl Compounds | 2010 |
Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17.
Topics: Amides; Androgens; Animals; Benzophenanthridines; Blotting, Western; Calcium; Colon; Cycloheximide; Dactinomycin; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; In Vitro Techniques; Male; Mice; Models, Biological; Models, Theoretical; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein Kinase C; Pyridines; Receptors, Androgen; rho-Associated Kinases; Signal Transduction; Testosterone | 2010 |
A mouse model of androgenetic alopecia.
Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Blotting, Western; Cell Line; Cell Line, Tumor; Dihydrotestosterone; Disease Models, Animal; Female; Flutamide; Hair; Humans; Keratin-5; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Protein Binding; Receptors, Androgen; Transfection | 2010 |
Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.
Topics: Androgen Antagonists; Androgens; Azacitidine; Blotting, Western; CpG Islands; Decitabine; Dihydrotestosterone; Disease Progression; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Promoter Regions, Genetic; Prostatic Neoplasms; Receptor, IGF Type 1; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 2010 |
A selective androgen receptor modulator enhances male-directed sexual preference, proceptive behavior, and lordosis behavior in sexually experienced, but not sexually naive, female rats.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Dihydrotestosterone; Estradiol; Female; Flutamide; Male; Ovariectomy; Progesterone; Pyrroles; Quinolones; Random Allocation; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal | 2010 |
Is the "comb over" dying? A mouse model for male pattern baldness (androgenic alopecia).
Topics: Alopecia; Androgen Antagonists; Androgens; Animals; beta Catenin; Dihydrotestosterone; Disease Models, Animal; Flutamide; Hair Follicle; Humans; Mice; Mice, Transgenic; Models, Biological; Protein Binding; Receptors, Androgen; Testosterone | 2010 |
Castration induces changes in the cation-dependent mannose-6-phosphate receptor in rat epididymis: possible implications in secretion of lysosomal enzymes.
Topics: alpha-Mannosidase; Animals; Blotting, Western; Cathepsin D; Dihydrotestosterone; Enzyme-Linked Immunosorbent Assay; Epididymis; Estradiol; Flutamide; Immunohistochemistry; Lysosomes; Male; Orchiectomy; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Receptors, Cytoplasmic and Nuclear; Testosterone | 2010 |
The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Androgens; Aniline Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coprinus; Dexamethasone; Dihydrotestosterone; Down-Regulation; Female; Flutamide; Gene Expression; Genes, Reporter; Humans; Inhibitory Concentration 50; Luciferases; Male; Mifepristone; Nitriles; Plant Extracts; Prostate-Specific Antigen; Prostatic Neoplasms; Quinolines; Receptors, Androgen; Receptors, Glucocorticoid; Tumor Stem Cell Assay; Up-Regulation | 2011 |
Changes of androgen receptor and insulin-like growth factor-1 in LNCaP prostate cancer cells treated with sex hormones and flutamide.
Topics: Androgen Antagonists; Androgens; Blotting, Western; Cell Line, Tumor; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
Androgen receptors in the posterior bed nucleus of the stria terminalis increase neuropeptide expression and the stress-induced activation of the paraventricular nucleus of the hypothalamus.
Topics: Analysis of Variance; Androgen Antagonists; Androgens; Animals; Arginine Vasopressin; Castration; Corticosterone; Dihydrotestosterone; Flutamide; Functional Laterality; Gene Expression Regulation; Glutamate Decarboxylase; Male; Neuropeptides; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Androgen; RNA, Messenger; Septal Nuclei; Stress, Psychological | 2011 |
Androgens modulate osteocalcin release by human visceral adipose tissue.
Topics: Adult; Androgen Antagonists; Androgens; Dihydrotestosterone; Flutamide; Humans; Intra-Abdominal Fat; Middle Aged; Osteocalcin; Overweight; Testosterone | 2011 |
Differential effects of exogenous androgen and an androgen receptor antagonist in the peri- and postpubertal murine mammary gland.
Topics: Androgen Antagonists; Animals; Apoptosis; Cell Proliferation; Dihydrotestosterone; Epithelial Cells; Estradiol; Female; Flutamide; Mammary Glands, Animal; Mice; Mice, Inbred C57BL; Receptors, Androgen; Receptors, Estrogen; Sexual Maturation | 2011 |
A novel steroidal antiandrogen targeting wild type and mutant androgen receptors.
Topics: Androgen Antagonists; Animals; Binding, Competitive; Carbamates; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Dihydrotestosterone; Drug Screening Assays, Antitumor; Flutamide; Humans; Male; Models, Molecular; Mutation; Prostate-Specific Antigen; Prostatic Neoplasms; Protein Transport; Receptors, Androgen; Structure-Activity Relationship; Transcriptional Activation | 2011 |
Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells.
Topics: Androgen Antagonists; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Dihydrotestosterone; Down-Regulation; Drug Synergism; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Receptors, Androgen; Resveratrol; RNA, Messenger; Stilbenes; Transcriptional Activation | 2011 |
Androgen signaling in decidualizing human endometrial stromal cells enhances resistance to oxidative stress.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Androgen Antagonists; Apoptosis; Dihydrotestosterone; Endometrium; Female; Flutamide; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Hysterectomy; Leiomyoma; Middle Aged; Oxidative Stress; Premenopause; Prolactin; Signal Transduction; Stromal Cells; Superoxide Dismutase; Superoxide Dismutase-1; Uterine Neoplasms | 2012 |
Androgen receptor signals regulate UDP-glucuronosyltransferases in the urinary bladder: a potential mechanism of androgen-induced bladder carcinogenesis.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Animals; Cell Line; Cystectomy; Dihydrotestosterone; Down-Regulation; Female; Flutamide; Follow-Up Studies; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Orchiectomy; Receptors, Androgen; Reference Values; Signal Transduction; UDP-Glucuronosyltransferase 1A9; Urinary Bladder; Urinary Bladder Neoplasms | 2013 |
Activation of PKR/eIF2α signaling cascade is associated with dihydrotestosterone-induced cell cycle arrest and apoptosis in human liver cells.
Topics: Androgen Antagonists; Apoptosis; Cell Cycle Checkpoints; Cell Line; Dihydrotestosterone; eIF-2 Kinase; Eukaryotic Initiation Factor-2; Flutamide; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; HSP27 Heat-Shock Proteins; Humans; Molecular Chaperones; Receptors, Androgen; Signal Transduction; Transcription Factor CHOP | 2012 |
Fluorinated and pegylated polyaspartamide derivatives to increase solubility and efficacy of Flutamide.
Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Chromatography, Gel; Dihydrotestosterone; Drug Carriers; Drug Delivery Systems; Ethylenediamines; Flutamide; Humans; Hydrophobic and Hydrophilic Interactions; Male; Micelles; Microscopy, Electron, Scanning; Oxadiazoles; Peptides; Polyethylene Glycols; Polymers; Prostatic Neoplasms; Solubility | 2012 |
Flutamide treatment induces anxiolytic-like behavior in adult castrated rats.
Topics: Androgen Antagonists; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Dihydrotestosterone; Drinking; Drug Interactions; Electroshock; Flutamide; Injections, Subcutaneous; Male; Motivation; Orchiectomy; Organ Size; Prostate; Rats; Rats, Wistar; Testosterone | 2012 |
Expression changes and regulation of AR and IGF-1 in PC3 prostate cancer cells treated with sexual hormones and flutamide.
Topics: Androgen Antagonists; Androgens; Blotting, Western; Dihydrotestosterone; Estrogens; Estrone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Insulin-Like Growth Factor I; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinase Inhibitors; Receptors, Androgen; Signal Transduction; Tumor Cells, Cultured | 2012 |
Orphan nuclear receptor NR4A1 is a negative regulator of DHT-induced rat preantral follicular growth.
Topics: Androgens; Animals; Cells, Cultured; Cyclin D2; Dihydrotestosterone; Down-Regulation; Female; Flutamide; Gene Expression; Gene Expression Regulation; Hyperandrogenism; Insulin; Ki-67 Antigen; Nuclear Receptor Subfamily 4, Group A, Member 1; Organ Culture Techniques; Ovarian Follicle; Ovary; Paracrine Communication; Proteins; Rats; Rats, Sprague-Dawley; Receptors, FSH; RNA, Messenger; Transcription, Genetic; Up-Regulation | 2012 |
Fluorescence lifetime imaging microscopy for the monitoring of green fluorescent protein-tagged androgen receptors in living cells.
Topics: Animals; Cell Survival; Chlorocebus aethiops; COS Cells; Dihydrotestosterone; Flutamide; Green Fluorescent Proteins; Microscopy, Fluorescence; Receptors, Androgen | 2013 |
Androgen/androgen receptor pathway regulates expression of the genes for cyclooxygenase-2 and amphiregulin in periovulatory granulosa cells.
Topics: Amphiregulin; Androgen Receptor Antagonists; Androgens; Animals; Chorionic Gonadotropin; Cyclooxygenase 2; Dihydrotestosterone; EGF Family of Proteins; Female; Flutamide; Glycoproteins; Granulosa Cells; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL | 2013 |
Androgens inhibit adipogenesis during human adipose stem cell commitment to preadipocyte formation.
Topics: Adipocytes; Adipogenesis; Adult Stem Cells; Androgen Antagonists; Androgens; Bone Morphogenetic Protein 4; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Dihydrotestosterone; Female; Flutamide; Gene Expression; Humans; Lipid Metabolism; PPAR gamma; Receptors, Androgen; Signal Transduction; Testosterone | 2013 |
Classifying chemical mode of action using gene networks and machine learning: a case study with the herbicide linuron.
Topics: Androgen Antagonists; Animals; Artificial Intelligence; Cyprinidae; Dihydrotestosterone; Endocrine Disruptors; Estradiol; Female; Flutamide; Gene Expression Profiling; Gene Regulatory Networks; Linuron; Ovary; Receptors, Androgen; Signal Transduction; Support Vector Machine; Water Pollutants, Chemical | 2013 |
Aberrant expression of the PRAC gene in prostate cancer.
Topics: Androgen Antagonists; Androgens; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Cell Line, Tumor; Decitabine; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Nuclear Proteins; Prostatic Neoplasms | 2013 |
Effects of androgens on early post-ischemic neurogenesis in mice.
Topics: Androgen Antagonists; Androgens; Animals; Brain Ischemia; Dentate Gyrus; Dihydrotestosterone; Flutamide; Male; Mice; Neurogenesis; Neurons; Stroke; Testosterone | 2014 |
Testosterone reduces knee passive range of motion and expression of relaxin receptor isoforms via 5α-dihydrotestosterone and androgen receptor binding.
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Animals; Blotting, Western; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Finasteride; Flutamide; Gene Expression; Knee Joint; Ovariectomy; Protein Binding; Range of Motion, Articular; Rats, Inbred WKY; Rats, Wistar; Receptors, Androgen; Receptors, G-Protein-Coupled; Receptors, Peptide; Relaxin; Reverse Transcriptase Polymerase Chain Reaction; Testosterone | 2014 |
Artificial masculinization in tilapia involves androgen receptor activation.
Topics: Androgen Antagonists; Androgens; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Dihydrotestosterone; Fadrozole; Female; Flutamide; Gonads; Humans; Male; Methyltestosterone; Receptors, Androgen; Sex Differentiation; Tilapia | 2014 |
Relationships between androgens, serotonin gene expression and innervation in male macaques.
Topics: Androgen Antagonists; Androgens; Animals; Aromatase; Aromatase Inhibitors; Axonal Transport; Axons; Castration; Dihydrotestosterone; Estradiol; Fenfluramine; Flutamide; Gene Expression; Locus Coeruleus; Macaca; Male; Prolactin; Receptor, Serotonin, 5-HT1A; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Testosterone; Tryptophan Hydroxylase | 2014 |
Prenatal influence of an androgen agonist and antagonist on the differentiation of the ovine sexually dimorphic nucleus in male and female lamb fetuses.
Topics: Androgen Antagonists; Androgens; Animals; Dihydrotestosterone; Female; Flutamide; Hypothalamo-Hypophyseal System; Kisspeptins; Luteinizing Hormone; Male; Pregnancy; Preoptic Area; Receptors, Androgen; Sex Characteristics; Sheep; Testosterone | 2014 |
Androgens promote the acquisition of maturation competence in bovine oocytes.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Cattle; Cell Nucleus; Dihydrotestosterone; Estradiol; Female; Flutamide; Granulosa Cells; Metaphase; Microscopy, Fluorescence; Oocytes; Receptors, Androgen | 2015 |
Androgen metabolites impact CSF amines and axonal serotonin via MAO-A and -B in male macaques.
Topics: Amines; Analysis of Variance; Androgen Antagonists; Androgens; Androstatrienes; Animals; Aromatase; Aromatase Inhibitors; Axons; Dihydrotestosterone; Flutamide; Macaca fascicularis; Male; Monoamine Oxidase; Raphe Nuclei; RNA, Messenger; Serotonin; Testosterone | 2015 |
Detecting the presence of hippocampus membrane androgen receptors in male SAMP8 mice and their induced synaptic plasticity.
Topics: Androgen Antagonists; Animals; Cell Membrane; Dendritic Spines; Dihydrotestosterone; Disks Large Homolog 4 Protein; Flutamide; Guanylate Kinases; Hippocampus; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Neuronal Plasticity; Receptors, Androgen; Synaptophysin; Testosterone | 2015 |
Hyperandrogenism and Insulin Resistance, Not Changes in Body Weight, Mediate the Development of Endothelial Dysfunction in a Female Rat Model of Polycystic Ovary Syndrome (PCOS).
Topics: Androgen Antagonists; Androgens; Animals; Arteries; Blood Pressure; Body Weight; Dihydrotestosterone; Endothelium, Vascular; Female; Flutamide; Hyperandrogenism; Hypoglycemic Agents; Insulin Resistance; Metformin; Polycystic Ovary Syndrome; Random Allocation; Rats, Wistar; Time Factors; Vasodilation | 2015 |
Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists.
Topics: Androgen Antagonists; beta Catenin; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Flutamide; Genes, Reporter; HEK293 Cells; Humans; Male; Prostatic Neoplasms; Receptors, Androgen | 2015 |
Testosterone regulates levels of cystic fibrosis transmembrane regulator, adenylate cyclase, and cAMP in the seminal vesicles of orchidectomized rats.
Topics: 5-alpha Reductase Inhibitors; Adenylate Kinase; Androgen Antagonists; Animals; Bicarbonates; Blotting, Western; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydrotestosterone; Finasteride; Flutamide; Male; Orchiectomy; Rats; Rats, Sprague-Dawley; Semen; Seminal Vesicles; Testosterone | 2016 |
Does anti-androgen, flutamide cancel out the in vivo effects of the androgen, dihydrotestosterone on sexual development in juvenile Murray rainbowfish (Melanotaenia fluviatilis)?
Topics: Androgen Antagonists; Androgens; Animals; Body Weight; Dihydrotestosterone; Environmental Exposure; Female; Flutamide; Hormones; Humans; Male; Ovary; Sexual Development; Smegmamorpha; Testis; Vitellogenins; Water Quality | 2016 |
Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome.
Topics: Adenylate Kinase; Animals; Cyclin-Dependent Kinase Inhibitor p21; Dihydrotestosterone; Endometrium; Female; Flutamide; Humans; In Vitro Techniques; Ki-67 Antigen; Phosphorylation; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Receptors, Androgen | 2015 |
The fluorescent two-hybrid assay for live-cell profiling of androgen receptor modulators.
Topics: Androgen Antagonists; Androgens; Androstadienes; Androstenes; Anilides; Animals; Benzamides; Benzimidazoles; Biological Assay; Cell Line; Cricetinae; Dihydrotestosterone; Flutamide; HEK293 Cells; Humans; Male; Microscopy, Fluorescence; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds; Transcription Factors; Two-Hybrid System Techniques | 2017 |
Regulation of sexual odor preference by sex steroids in the posterodorsal medial amygdala in female rats.
Topics: Amygdala; Animals; Choice Behavior; Corticomedial Nuclear Complex; Dihydrotestosterone; Estrogens; Estrus; Female; Flutamide; Male; Marriage; Odorants; Rats; Rats, Long-Evans; Receptors, Androgen; Sexual Behavior; Sexual Behavior, Animal; Testosterone | 2016 |
Corepressive function of nuclear receptor coactivator 2 in androgen receptor of prostate cancer cells treated with antiandrogen.
Topics: Androgen Antagonists; Anilides; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Mutation; Nitriles; Nuclear Receptor Coactivators; Prostatic Neoplasms; Receptors, Androgen; Tosyl Compounds | 2016 |
Enzalutamide inhibits androgen receptor-positive bladder cancer cell growth.
Topics: Androgen Antagonists; Anilides; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dihydrotestosterone; Down-Regulation; Flutamide; Humans; Interleukin-6; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Nitriles; Phenylthiohydantoin; Receptors, Androgen; RNA; Tosyl Compounds; Transcription, Genetic; Urinary Bladder Neoplasms | 2016 |
Neuroprotective effects of testosterone metabolites and dependency on receptor action on the morphology of somatic motoneurons following the death of neighboring motoneurons.
Topics: Androgen Antagonists; Animals; Cell Death; Cholera Toxin; Dendrites; Dihydrotestosterone; Flutamide; Horseradish Peroxidase; Male; Motor Neurons; Muscle, Skeletal; Nerve Net; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Tamoxifen; Testosterone | 2017 |
Androgen Stimulates Growth of Mouse Preantral Follicles In Vitro: Interaction With Follicle-Stimulating Hormone and With Growth Factors of the TGFβ Superfamily.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Cells, Cultured; Dihydrotestosterone; Down-Regulation; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Mice; Ovarian Follicle; Receptors, FSH; Signal Transduction; Testosterone; Transforming Growth Factor beta | 2017 |
In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines.
Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Dog Diseases; Dogs; Estradiol; Estrone; Female; Flutamide; Gonadal Steroid Hormones; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnenolone; Progesterone; Testosterone | 2018 |
Prenatal androgen receptor activation determines adult alcohol and water drinking in a sex-specific way.
Topics: Alcohol Drinking; Androgen Receptor Antagonists; Androgens; Animals; Brain-Derived Neurotrophic Factor; Dihydrotestosterone; Drinking Behavior; Female; Flutamide; Gene Expression; Male; Mice; Period Circadian Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Androgen; RNA, Messenger; Sex Factors; Water | 2018 |
Androgens Upregulate Endometrial Epithelial Progesterone Receptor Expression: Potential Implications for Endometriosis.
Topics: Androgen Antagonists; Androgens; Dihydrotestosterone; Endometriosis; Endometrium; Epithelial Cells; Female; Flutamide; Humans; Receptors, Androgen; Receptors, Progesterone; Stromal Cells; Up-Regulation | 2017 |
Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Animals, Newborn; Brain; Dihydrotestosterone; Female; Flutamide; Male; Mice; Mice, Inbred C57BL; Myelin Sheath; Receptors, Androgen; Sex Differentiation | 2017 |
Prenatal androgen-receptor activity has organizational morphological effects in mice.
Topics: Animals; Body Size; Dihydrotestosterone; Extremities; Female; Flutamide; Functional Laterality; Gonadal Steroid Hormones; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Androgen | 2017 |
Role for androgens in determination of ovarian fate in the common snapping turtle, Chelydra serpentina.
Topics: Androgens; Animals; Dihydrotestosterone; Embryo, Nonmammalian; Female; Flutamide; Gene Expression Regulation, Developmental; Male; Ovary; Sex Ratio; Testis; Turtles | 2019 |
Low-Intensity Exercise Suppresses CCAAT/Enhancer-Binding Protein δ/Myostatin Pathway Through Androgen Receptor in Muscle Cells.
Topics: Androgen Antagonists; Animals; CCAAT-Enhancer-Binding Protein-delta; Dihydrotestosterone; Electric Stimulation; Flutamide; In Vitro Techniques; Interleukin-6; Mice; Muscle Fibers, Skeletal; Myogenin; Myostatin; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Real-Time Polymerase Chain Reaction; Receptors, Androgen; Signal Transduction; STAT3 Transcription Factor; Testosterone; Transcriptome | 2019 |
A human-derived prostate co-culture microtissue model using epithelial (RWPE-1) and stromal (WPMY-1) cell lines.
Topics: Androgen Antagonists; Androgens; Animal Testing Alternatives; Cell Line; Coculture Techniques; Cytochrome P-450 CYP1B1; Dihydrotestosterone; Estrogen Receptor alpha; Estrogen Receptor beta; Flutamide; Gene Expression Regulation; Humans; Hydrogels; Male; Prostate; Receptors, Androgen | 2019 |
Structural Dynamics of Agonist and Antagonist Binding to the Androgen Receptor.
Topics: Androgen Receptor Antagonists; Androgens; Anilides; Binding Sites; Dihydrotestosterone; Flutamide; Humans; Molecular Dynamics Simulation; Nitriles; Receptors, Androgen; Testosterone; Tosyl Compounds | 2019 |
Prenatal low-dose methyltestosterone, but not dihydrotestosterone, treatment induces penile formation in female mice and guinea pigs†.
Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Animals; Animals, Newborn; Cell Death; Cell Proliferation; Dihydrotestosterone; Drug Therapy, Combination; Female; Flutamide; Genitalia, Female; Guinea Pigs; Male; Methyltestosterone; Mice; Penis; Pregnancy; Receptors, Androgen; Sex Determination Analysis; Testosterone | 2020 |
Androgen Affects the Dynamics of Intrinsic Plasticity of Pyramidal Neurons in the CA1 Hippocampal Subfield in Adolescent Male Rats.
Topics: Androgens; Animals; Dihydrotestosterone; Flutamide; Hippocampus; Male; Pyramidal Cells; Rats; Receptors, Androgen | 2020 |
Histone H2A.Z is required for androgen receptor-mediated effects on fear memory.
Topics: Androgen Receptor Antagonists; Androgens; Animals; Dihydrotestosterone; Fear; Flutamide; Hippocampus; Histones; Male; Memory; Mice; Mice, Knockout; Neurons; Orchiectomy; Receptors, Androgen | 2020 |
Controlled dual release of dihydrotestosterone and flutamide from polycaprolactone electrospun scaffolds accelerate burn wound healing.
Topics: Androgen Antagonists; Androgens; Animals; Burns; Dihydrotestosterone; Flutamide; Humans; Mice; Polyesters; Tissue Scaffolds; Wound Healing | 2022 |
Intracellular distribution of vinclozolin and its metabolites differently affects 5α-dihydrotestosterone (DHT)-induced PSA secretion in LNCaP cells.
Topics: Androgen Antagonists; Androgens; Cell Line, Tumor; Dihydrotestosterone; Flutamide; Humans; Male; Oxazoles; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen | 2022 |
Effect of dihydrotestosterone on melatonin secretion and the expression of melatonin receptors and apoptosis-related factors in sheep epididymides.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Dihydrotestosterone; Epididymis; Flutamide; Ligases; Male; Melatonin; Receptors, Androgen; Receptors, Melatonin; RNA, Messenger; Semen; Sheep | 2022 |
Androgen receptor coordinates muscle metabolic and contractile functions.
Topics: Androgens; Animals; Diabetes Mellitus, Type 2; Dihydrotestosterone; Female; Flutamide; Male; Mice; Muscle Contraction; Muscle, Skeletal; Receptors, Androgen | 2023 |