flutamide and androstenedione

flutamide has been researched along with androstenedione in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199013 (23.21)18.7374
1990's23 (41.07)18.2507
2000's13 (23.21)29.6817
2010's6 (10.71)24.3611
2020's1 (1.79)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Harman, SM; Louvet, JP; Ross, GT; Schrieber, JR1
Kirschner, MA; Luthold, WW; Marcondes, JA; Minnani, SL; Samojlik, E; Wajchenberg, BL1
Couêt, J; Labrie, C; Labrie, F; Li, S; Martel, C; Trudel, C1
Ayub, M; Levell, MJ1
Callard, GV; Schlinger, BA1
Dauvois, S; Labrie, F1
Belanger, A; Labrie, C; Labrie, F; Pelletier, G; Simard, J; Zhao, HF1
Hammond, JM; Spicer, LJ1
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F1
Bégin, D; Labrie, F; Luthy, IA1
Brodie, AM; Catt, KJ; Knecht, M1
Duleba, AJ; Ho Yuen, B; Kim, KS; Moon, YS1
Brodie, AM; Hammond, JO; Wing, LY1
Bélanger, A; Labrie, F; Marchetti, B; Mérand, Y; Spinola, PG1
Baker, D; Labrie, F; Poulin, R1
Bertagna, C; Coussedière, D; Husson, JM; Moguilewsky, M; Pendyala, L; Pottier, J; Raynaud, JP; Salmon, J; Tournemine, C; Tremblay, D1
Belanger, A; Le Goff, JM1
el Etreby, MF; Habenicht, UF1
Armanini, D; Castello, R; Fontanarosa, MC; Magnani, CM; Moghetti, P; Muggeo, M; Negri, C; Tosi, F1
Benz, R; Rossmanith, WG; Schenkel, B1
Rabenbauer, B; Sir-Petermann, T; Wildt, L1
Bélanger, A; Couet, J; Labrie, C; Labrie, F; Martel, C; Trudel, C1
Halushka, PV; Higashiura, K; Mathur, RS; Zucker, TP1
Ayata, D; Bayram, F; Keleştimur, F; Müderris, II; Sahin, Y; Tutuş, A1
di Salle, E; Giudici, D; Zaccheo, T1
Galosy, S; Gudmundsson, GO; Newcomer, B; Sridaran, R; Talamantes, F; Thordarson, G1
De Fusco, D; Eleftheriou, G; Falsetti, L; Rosina, B1
Barañao, JL; Bley, MA; Saragüeta, PE1
Candas, B; Chen, C; Labrie, C; Labrie, F; Luo, S; Martel, C; Singh, SM1
D'Antona, D; De Leo, V; la Marca, A; Lanzetta, D; Morgante, G1
Machelon, V; Nomé, F; Tesarik, J1
Diamanti-Kandarakis, E; Duleba, AJ; Mitrakou, A; Raptis, S; Tolis, G1
Coscia, EM; Drea, CM; Forger, NG; Frank, LG; Glickman, SE; Licht, P; Weldele, ML1
Cariello, PL; D'Antona, D; De Leo, V; la Marca, A; Lanzetta, D; Morgante, G1
Balk, SP; Bubley, GJ; Fenton, MA; Fertig, AM; Kolvenbag, G; Shuster, TD; Taplin, ME1
Bayram, F; Müderris, II1
Damien, E; Lanyon, LE; Price, JS1
Shilling, AD; Williams, DE1
Chen, Q; Chihara, K; Kaji, H; Sugimoto, T1
Cacciari, M; Carcello, A; De Iasio, R; Gambineri, A; Manicardi, E; Pagotto, U; Pasquali, R; Tschöp, M; Vicennati, V1
Dvoráková, K; Hill, M; Stanická, S; Stárka, L; Vondra, K; Vrbíková, J1
Bahceci, M; Bahceci, S; Bilge, M; Tuzcu, A; Tuzcu, S1
Er, F; Gassanov, N; Hoppe, UC; Michels, G; Rivero, F1
Anido, M; Bacallao, K; Clementi, M; Johnson, C; Maliqueo, MA; Quezada, S; Vega, M1
Chang, RJ; Malcom, PJ; Mehta, RV1
Casais, M; Delgado, SM; Filippa, V; Mohamed, F; Rastrilla, AM; Sosa, Z; Vallcaneras, SS1
Coscia, EM; Dahl, NJ; Drea, CM; Glickman, SE; Holekamp, KE; Place, NJ; Roser, JF; Sisk, CL; Weldele, ML1
Panter, GH; Thorpe, KL; Weltje, L; Wheeler, JR1
Ciereszko, RE; Grzesiak, M; Knapczyk-Stwora, K; Slomczynska, M; Wieciech, I1
Acosta, JI; Alderete, TJ; Bimonte-Nelson, HA; Camp, BW; Demers, LM; Koebele, SV; Mennenga, SE; Mousa, AA; Tsang, CW1
Anai, S; Fujimoto, K; Miyake, M; Nakai, Y; Tanaka, N; Tatsumi, Y1
Alonso-Diez, A; Caceres, S; de Andres, PJ; Illera, JC; Illera, MJ; Monsalve, B; Peña, L; Reuben, JM; Silvan, G; Woodward, WA1
Hinchcliffe, JK; Mendl, M; Robinson, ESJ1

Reviews

2 review(s) available for flutamide and androstenedione

ArticleYear
The function and the role of aromatase inhibitors in the treatment of BPH.
    Progress in clinical and biological research, 1994, Volume: 386

    Topics: Androgens; Androstenedione; Animals; Aromatase Inhibitors; Clinical Trials as Topic; Disease Models, Animal; Estrogens; Flutamide; Humans; Macaca fascicularis; Male; Prostate; Prostatic Hyperplasia

1994
Test concentration setting for fish in vivo endocrine screening assays.
    Chemosphere, 2013, Volume: 92, Issue:9

    Topics: Androstenedione; Animals; Endocrine Disruptors; Ethylene Glycols; Fishes; Flutamide; Imidazoles; Ketoconazole; Maximum Tolerated Dose; Octanols; Phenols; Potassium Permanganate; Sodium Dodecyl Sulfate

2013

Trials

9 trial(s) available for flutamide and androstenedione

ArticleYear
Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor behavior.
    Fertility and sterility, 1995, Volume: 64, Issue:3

    Topics: Acne Vulgaris; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Hirsutism; Humans; Leukocytes, Mononuclear; Receptors, Androgen; Testosterone

1995
Role of androgens in the regulation of the human menstrual cycle.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1994, Volume: 8, Issue:3

    Topics: Administration, Oral; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Humans; Luteinizing Hormone; Menstrual Cycle; Progesterone; Radioimmunoassay; Receptors, Androgen; Sex Hormone-Binding Globulin; Testosterone

1994
The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism.
    Fertility and sterility, 1996, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Dose-Response Relationship, Drug; Estrogens; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Progesterone; Prospective Studies; Testosterone

1996
Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1997, Volume: 11, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone Sulfate; Female; Finasteride; Flutamide; Hirsutism; Humans; Insulin; Luteinizing Hormone; Polycystic Ovary Syndrome; Testosterone

1997
Hormonal effects of flutamide in young women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:1

    Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Sex Hormone-Binding Globulin; Testosterone; Time Factors

1998
Clinical efficacy of lower dose flutamide 125 mg/day in the treatment of hirsutism.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Androgen Antagonists; Androstenedione; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Hirsutism; Humans; Luteinizing Hormone; Prolactin; Sex Hormone-Binding Globulin; Testosterone

1999
Anti-androgen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:7

    Topics: Adult; Androgen Antagonists; Androstenedione; Blood Glucose; Body Composition; Body Weight; Female; Flutamide; Ghrelin; Glucose Tolerance Test; Gonadal Steroid Hormones; Hormones; Humans; Obesity; Peptide Hormones; Polycystic Ovary Syndrome; Testosterone

2003
Alterations in luteal production of androstenedione, testosterone, and estrone, but not estradiol, during mid- and late pregnancy in pigs: effects of androgen deficiency.
    Theriogenology, 2014, Sep-15, Volume: 82, Issue:5

    Topics: 17-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androstenedione; Animals; Aromatase; Corpus Luteum; Estradiol; Estrone; Female; Flutamide; Gene Expression Regulation, Enzymologic; Pregnancy; Steroid 17-alpha-Hydroxylase; Swine; Testosterone

2014
A Randomized Control Trial Comparing the Efficacy of Antiandrogen Monotherapy: Flutamide vs. Bicalutamide.
    Hormones & cancer, 2015, Volume: 6, Issue:4

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenedione; Anilides; Dehydroepiandrosterone; Flutamide; Humans; Male; Neoplasm Staging; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms; Testosterone; Tosyl Compounds

2015

Other Studies

45 other study(ies) available for flutamide and androstenedione

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Evidence of a role of adrogens in follicular maturation.
    Endocrinology, 1975, Volume: 97, Issue:2

    Topics: Androgens; Androstenedione; Animals; Chorionic Gonadotropin; Cyproterone; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Female; Flutamide; Humans; Hydrocortisone; Hydroxyprogesterones; Hypophysectomy; Organ Size; Ovarian Follicle; Ovary; Pituitary Gland; Progesterone; Rats; Testosterone

1975
Treatment of hirsutism in women with flutamide.
    Fertility and sterility, 1992, Volume: 57, Issue:3

    Topics: Adult; Analysis of Variance; Androstane-3,17-diol; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Hirsutism; Humans; Polycystic Ovary Syndrome; Sex Hormone-Binding Globulin; Testosterone; Treatment Outcome

1992
Combination of an antiandrogen and a 5 alpha-reductase inhibitor: a further step towards total androgen blockade?
    Endocrinology, 1991, Volume: 129, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Androstanes; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Drug Interactions; Flutamide; Male; Organ Size; Prostate; Prostatein; Rats; Rats, Inbred Strains; RNA, Messenger; Secretoglobins; Uteroglobin

1991
Suppression of plasma androgens by the antiandrogen flutamide in prostatic cancer patients treated with Zoladex, a GnRH analogue.
    Clinical endocrinology, 1990, Volume: 32, Issue:3

    Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androgens; Androstenedione; Anilides; Antineoplastic Agents; Buserelin; Dehydroepiandrosterone; Depression, Chemical; Flutamide; Goserelin; Humans; Hydroxyprogesterones; Male; Orchiectomy; Prostatic Neoplasms; Testosterone

1990
Aromatization mediates aggressive behavior in quail.
    General and comparative endocrinology, 1990, Volume: 79, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Aggression; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Azasteroids; Behavior, Animal; Coturnix; Dihydrotestosterone; Estradiol; Female; Flutamide; Hypothalamus; Male; Motor Activity; Nitromifene; Preoptic Area; Quail; Testosterone

1990
Androstenedione and androst-5-ene-3 beta,17 beta-diol stimulate DMBA-induced rat mammary tumors--role of aromatase.
    Breast cancer research and treatment, 1989, Volume: 13, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenediol; Androstenediols; Androstenedione; Animals; Aromatase; Female; Flutamide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Silicone Elastomers

1989
Stimulation of androgen-dependent gene expression by the adrenal precursors dehydroepiandrosterone and androstenedione in the rat ventral prostate.
    Endocrinology, 1989, Volume: 124, Issue:6

    Topics: Adrenal Glands; Androgen-Binding Protein; Androgens; Androstenedione; Animals; Autoradiography; Carrier Proteins; Dehydroepiandrosterone; Flutamide; Genes; Intracellular Signaling Peptides and Proteins; Kinetics; Male; Orchiectomy; Prostate; Prostatein; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Secretoglobins; Sulfur Radioisotopes; Time Factors; Transcription, Genetic; Uteroglobin

1989
Comparative effects of androgens and catecholestrogens on progesterone production by porcine granulosa cells.
    Molecular and cellular endocrinology, 1988, Volume: 56, Issue:3

    Topics: 2-Methoxyestradiol; Androstenedione; Animals; Cell Count; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Ovum; Progesterone; Swine; Testosterone

1988
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate

1988
Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro.
    Molecular and cellular endocrinology, 1988, Volume: 58, Issue:2-3

    Topics: Androgens; Androstenediol; Androstenediols; Androstenedione; Animals; Cell Line; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Flutamide; Growth; Male; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured

1988
Aromatase inhibitors prevent granulosa cell differentiation: an obligatory role for estrogens in luteinizing hormone receptor expression.
    Endocrinology, 1985, Volume: 117, Issue:3

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Cell Differentiation; Cells, Cultured; Cyclic AMP; Delayed-Action Preparations; Diethylstilbestrol; Estradiol; Estrogens; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Oxidoreductases; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Cell Surface; Receptors, LH; Time Factors

1985
Inhibition of 20 alpha-hydroxysteroid dehydrogenase activity by follicle-stimulating hormone and androgens in cultured rat granulosa cells: a search for the mechanism of action.
    Biology of reproduction, 1985, Volume: 33, Issue:2

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Androgens; Androstenedione; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Dihydrotestosterone; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; Rats; Rats, Inbred Strains; Testosterone

1985
Differential responses of sex steroid target tissues of rats treated with 4-hydroxyandrostenedione.
    Endocrinology, 1988, Volume: 122, Issue:6

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Kinetics; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Uterus

1988
Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors.
    Breast cancer research and treatment, 1988, Volume: 12, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Anilides; Animals; Cell Division; Female; Flutamide; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Steroids

1988
Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line.
    Breast cancer research and treatment, 1988, Volume: 12, Issue:2

    Topics: Androgen Antagonists; Androstenedione; Breast Neoplasms; Cell Division; Cell Line; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Flutamide; Humans; Piperidines; Raloxifene Hydrochloride; Receptors, Androgen; Receptors, Estrogen; Testosterone

1988
Pharmacology and clinical studies with RU 23908 (Anandron).
    Progress in clinical and biological research, 1985, Volume: 185A

    Topics: Androgen Antagonists; Androstenedione; Animals; Castration; Diethylstilbestrol; Flutamide; Humans; Imidazoles; Imidazolidines; Kinetics; Male; Organ Size; Prostate; Prostatic Neoplasms; Rats

1985
Metabolism of tritiated C19 steroids by Shionogi mouse mammary tumors.
    Steroids, 1984, Volume: 44, Issue:3

    Topics: Androgens; Androstenediols; Androstenedione; Androsterone; Animals; Castration; Dehydroepiandrosterone; Dihydrotestosterone; Estrogens; Flutamide; Male; Mammary Neoplasms, Experimental; Mice; Steroid Isomerases; Testosterone

1984
The effect of flutamide on pulsatile gonadotrophin secretion in hyperandrogenaemic women.
    Human reproduction (Oxford, England), 1993, Volume: 8, Issue:11

    Topics: Adolescent; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Humans; Hyperandrogenism; Luteinizing Hormone; Sex Hormone-Binding Globulin; Testosterone

1993
Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA.
    Molecular and cellular endocrinology, 1993, Volume: 91, Issue:1-2

    Topics: 5-alpha Reductase Inhibitors; Androgen-Binding Protein; Androgens; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Flutamide; In Situ Hybridization; Male; Orchiectomy; Organ Size; Phosphatidylethanolamine Binding Protein; Prostate; Prostatein; Rats; Rats, Sprague-Dawley; RNA, Messenger; Secretoglobins; Uteroglobin

1993
Androstenedione increases thromboxane A2 receptors in human erythroleukemia cells.
    Life sciences, 1996, Volume: 58, Issue:8

    Topics: Androgen Antagonists; Androstenedione; Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Drug Interactions; Fatty Acids, Unsaturated; Flutamide; Humans; Indomethacin; Iodine Radioisotopes; Kinetics; Leukemia, Erythroblastic, Acute; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Receptors, Thromboxane; Testosterone; Time Factors; Tumor Cells, Cultured

1996
Effect of turosteride, a 5 alpha-reductase inhibitor, on the Dunning R3327 rat prostatic carcinoma.
    The Prostate, 1997, Feb-01, Volume: 30, Issue:2

    Topics: 5-alpha Reductase Inhibitors; Adenocarcinoma; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Dihydrotestosterone; Enzyme Inhibitors; Finasteride; Flutamide; Leuprolide; Luteinizing Hormone; Male; Organ Size; Pituitary Gland, Anterior; Prostate; Prostatic Neoplasms; Random Allocation; Rats; Seminal Vesicles; Testis; Testosterone

1997
Interaction of mouse placental lactogens and androgens in regulating progesterone release in cultured mouse luteal cells.
    Endocrinology, 1997, Volume: 138, Issue:8

    Topics: Androgen Receptor Antagonists; Androgens; Androstenedione; Animals; Aromatase Inhibitors; Cattle; Cells, Cultured; Cycloheximide; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fadrozole; Female; Flutamide; Luteal Cells; Mice; Placental Lactogen; Pregnancy; Progesterone; Prolactin; Protein Synthesis Inhibitors; Rabbits; Testosterone

1997
Concerted stimulation of rat granulosa cell deoxyribonucleic acid synthesis by sex steroids and follicle-stimulating hormone.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 62, Issue:1

    Topics: Androgen Antagonists; Androgens; Androstenedione; Androsterone; Animals; Bucladesine; Cells, Cultured; Diethylstilbestrol; Dihydrotestosterone; DNA; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Insulin; Insulin-Like Growth Factor I; Kinetics; Medroxyprogesterone; Ovary; Progesterone; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Testosterone; Thymidine

1997
Daily dosing with flutamide or Casodex exerts maximal antiandrogenic activity.
    Urology, 1997, Volume: 50, Issue:6

    Topics: Androgen Antagonists; Androstenedione; Anilides; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Dose-Response Relationship, Drug; Drug Implants; Flutamide; Male; Mice; Mice, Inbred Strains; Nitriles; Orchiectomy; Organ Size; Prostate; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Tosyl Compounds

1997
Nongenomic effects of androstenedione on human granulosa luteinizing cells.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:1

    Topics: Actins; Androstenedione; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Egtazic Acid; Endoplasmic Reticulum; Enzyme Inhibitors; Female; Flutamide; Granulosa Cells; Humans; Kinetics; Lipopolysaccharide Receptors; Ovarian Follicle; Pertussis Toxin; Polymerase Chain Reaction; Receptors, Androgen; Testosterone; Thapsigargin; Type C Phospholipases; Verapamil; Virulence Factors, Bordetella

1998
The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:8

    Topics: Adult; Androgen Antagonists; Androstane-3,17-diol; Androstenedione; Cholesterol; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Hyperlipidemias; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Liver Function Tests; Obesity; Polycystic Ovary Syndrome; Testosterone; Triglycerides

1998
Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 2. Effects of prenatal anti-androgens.
    Journal of reproduction and fertility, 1998, Volume: 113, Issue:1

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androstenedione; Animals; Carnivora; Cyproterone Acetate; Enzyme Inhibitors; Female; Finasteride; Flutamide; Genitalia; Male; Maternal-Fetal Exchange; Pregnancy; Sex Differentiation; Urogenital System

1998
Effects of flutamide on pituitary and adrenal responsiveness to corticotrophin releasing factor (CRF).
    Clinical endocrinology, 1998, Volume: 49, Issue:1

    Topics: 17-alpha-Hydroxyprogesterone; Adrenocorticotropic Hormone; Adult; Androgen Antagonists; Androgens; Androstenedione; Area Under Curve; Corticotropin-Releasing Hormone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Hydrocortisone; Pituitary-Adrenal System; Polycystic Ovary Syndrome; Testosterone

1998
Functional characterization of mutant androgen receptors from androgen-independent prostate cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:8

    Topics: Amino Acid Substitution; Androgen Antagonists; Androgens; Androstenedione; Animals; beta-Galactosidase; Cell Line; Dihydrotestosterone; Estradiol; Flutamide; Genes, Reporter; Imidazoles; Imidazolidines; Luciferases; Male; Point Mutation; Progesterone; Prostatic Neoplasms; Receptors, Androgen; Recombinant Fusion Proteins; Transfection

1997
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:11

    Topics: Androgen Antagonists; Androstenedione; Animals; Antibodies; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flutamide; Fulvestrant; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Male; Osteoblasts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Stress, Mechanical; Tamoxifen; Testosterone; Thymidine

2000
The non-aromatizable androgen, dihydrotestosterone, induces antiestrogenic responses in the rainbow trout.
    The Journal of steroid biochemistry and molecular biology, 2000, Nov-15, Volume: 74, Issue:4

    Topics: Androgen Antagonists; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Female; Flutamide; Liver; Male; Microsomes, Liver; Oncorhynchus mykiss; Receptors, Androgen; Sex Factors; Vitellogenins

2000
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor.
    FEBS letters, 2001, Feb-23, Volume: 491, Issue:1-2

    Topics: Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Cell Division; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flutamide; Fulvestrant; Glucuronates; Mice; Mice, Inbred ICR; Osteoclasts; Parathyroid Hormone; Receptors, Androgen; Teriparatide; Testosterone

2001
Flutamide suppresses adrenal steroidogenesis but has no effect on insulin resistance and secretion and lipid levels in overweight women with polycystic ovary syndrome.
    Gynecologic and obstetric investigation, 2004, Volume: 58, Issue:1

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgen Antagonists; Androgens; Androstenedione; Body Mass Index; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Flutamide; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipids; Obesity; Polycystic Ovary Syndrome; Steroids; Testosterone

2004
Serum prostate specific antigen levels in women with polycystic ovary syndrome and the effect of flutamide+desogestrel/ethinyl estradiol combination.
    Journal of endocrinological investigation, 2004, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Androgen Antagonists; Androgens; Androstenedione; Contraceptives, Oral, Hormonal; Desogestrel; Drug Therapy, Combination; Ethinyl Estradiol; Female; Flutamide; Hirsutism; Humans; Insulin; Luteinizing Hormone; Polycystic Ovary Syndrome; Prostate-Specific Antigen; Testosterone

2004
Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane.
    Circulation, 2004, Nov-09, Volume: 110, Issue:19

    Topics: Adenosine Triphosphate; Androgen Receptor Antagonists; Androstenedione; Animals; Biological Transport, Active; Cells, Cultured; Diazoxide; Flutamide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Ion Transport; Male; Membrane Proteins; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Myocardial Ischemia; Myocytes, Cardiac; Patch-Clamp Techniques; Pinacidil; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Testosterone

2004
Potential action of androstenedione on the proliferation and apoptosis of stromal endometrial cells.
    Reproductive biology and endocrinology : RB&E, 2004, Dec-10, Volume: 2

    Topics: Actins; Adult; Androstenedione; Apoptosis; bcl-2-Associated X Protein; Cell Proliferation; Cells, Cultured; Endometrium; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Flutamide; Humans; In Situ Nick-End Labeling; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells

2004
The effect of androgen blockade on granulosa cell estradiol production after follicle-stimulating hormone stimulation in women with polycystic ovary syndrome.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:9

    Topics: Adult; Androgen Antagonists; Androstenedione; Area Under Curve; Cohort Studies; Dehydroepiandrosterone Sulfate; Estradiol; Estrone; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Humans; Luteinizing Hormone; Polycystic Ovary Syndrome; Progesterone; Prospective Studies; Recombinant Proteins; Sex Hormone-Binding Globulin; Testosterone

2006
Androgen receptors in coeliac ganglion in late pregnant rat.
    Steroids, 2009, Volume: 74, Issue:6

    Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 3-Hydroxysteroid Dehydrogenases; Androgen Antagonists; Androstenedione; Animals; Corpus Luteum; Female; Flutamide; Ganglia, Sympathetic; Immunohistochemistry; Male; Nitriles; Ovary; Pregnancy; Progesterone; Rats; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2009
The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males.
    General and comparative endocrinology, 2011, Feb-01, Volume: 170, Issue:3

    Topics: Androgen Antagonists; Androstenedione; Animals; Estradiol; Feedback; Female; Finasteride; Flutamide; Hyaenidae; Luteinizing Hormone; Male; Pregnancy; Progesterone; Sex Differentiation; Sex Factors; Testosterone

2011
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition Disorders; Estrone; Female; Flutamide; Maze Learning; Menopause; Nitriles; Ovariectomy; Rats, Inbred F344; Receptors, Androgen; Triazoles; Uterus

2015
In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Dihydrotestosterone; Dog Diseases; Dogs; Estradiol; Estrone; Female; Flutamide; Gonadal Steroid Hormones; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnenolone; Progesterone; Testosterone

2018
Investigating hormone-induced changes in affective state using the affective bias test in male and female rats.
    Psychoneuroendocrinology, 2020, Volume: 115

    Topics: Affect; Androstenedione; Animals; Behavior, Animal; Benzhydryl Compounds; Deamino Arginine Vasopressin; Estradiol; Female; Flutamide; Hormones; Male; Oxytocin; Phenols; Progesterone; Rats; Rats, Sprague-Dawley; Sex Factors; Testosterone

2020