flustramine-c and indoline

flustramine-c has been researched along with indoline* in 1 studies

Other Studies

1 other study(ies) available for flustramine-c and indoline

Article	Year
Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms. Organic & biomolecular chemistry, 2011, Aug-07, Volume: 9, Issue:15 Anti-biofilm agents have been developed based upon the flustramine family of alkaloids isolated from Flustra foliacea. A Garg interrupted Fischer indolization reaction was employed to access a core pyrroloindoline scaffold that was subsequently employed to create a pyrroloindoline triazole amide library. Screening for the ability to modulate biofilm formation against strains of Gram-positive and Gram-negative bacteria identified several compounds with low micromolar, non-toxic IC(50) values. Topics: Amides; Anti-Bacterial Agents; Bacteria; Biofilms; Indole Alkaloids; Indoles; Inhibitory Concentration 50; Molecular Structure; Pyrroles; Quantitative Structure-Activity Relationship; Small Molecule Libraries	2011

Article

Year

Flustramine inspired synthesis and biological evaluation of pyrroloindoline triazole amides as novel inhibitors of bacterial biofilms.

Organic & biomolecular chemistry, 2011, Aug-07, Volume: 9, Issue:15

Anti-biofilm agents have been developed based upon the flustramine family of alkaloids isolated from Flustra foliacea. A Garg interrupted Fischer indolization reaction was employed to access a core pyrroloindoline scaffold that was subsequently employed to create a pyrroloindoline triazole amide library. Screening for the ability to modulate biofilm formation against strains of Gram-positive and Gram-negative bacteria identified several compounds with low micromolar, non-toxic IC(50) values.

Topics: Amides; Anti-Bacterial Agents; Bacteria; Biofilms; Indole Alkaloids; Indoles; Inhibitory Concentration 50; Molecular Structure; Pyrroles; Quantitative Structure-Activity Relationship; Small Molecule Libraries

2011