flurbiprofen and thromboxane b2

flurbiprofen has been researched along with thromboxane b2 in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.83)18.7374
1990's13 (54.17)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Abramson, MM; Aeppli, DM; Friedman, HM; Hardie, ND; Offenbacher, S; Wolff, LF1
Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Odle, BM; Offenbacher, S; Smith, MA; Williams, RC1
Antal, EJ; Buchanan, WW; Cauvier, H; Grace, EM; Kean, WF; Rischke, J1
Brune, K; Kluge, S; Peskar, BA; Peskar, BM; Soglowek, SM1
Bolling, SF; Deeb, GM; Grum, CM; Ljungman, AG; Morganroth, ML1
Cyran, JA; Lea, MA; Lysz, TW1
Holgate, ST; Lai, CK; Polosa, R; Robinson, C1
Barnes, PJ; Giembycz, MA; Kroegel, C1
Fuller, RW; Joyce, H; Lim, TK; Pride, NB; Turner, NC; Watson, A1
Caen, J; Corvazier, E; Maclouf, J; Pintigny, D; Wautier, JL; Wautier, MP1
Ding, YA; Kenyon, CJ; MacIntyre, DE; Semple, PF1
Brown, CG; Poyser, NL1
Avellone, G; Custro, N; Davì, G; Mattina, A; Novo, S; Riolo, FP; Strano, A2
Collins, JG; Edwards, G; Heasman, PA; Offenbacher, S; Seymour, RA1
Baker, AJ; Brightling, CE; Fuller, RW1
Del Soldato, P; di Giamberardino, M; Padovano, R; Panara, MR; Patrignani, P; Rotondo, MT; Santini, G; Sciulli, MG1
Brune, K; Geisslinger, G; Neupert, W; Oelkers, R; Williams, KM1
Carballosa Coré-Bodelier, VM; Van Delft, JL; van Haeringen, NJ; van Sorge, AA1
Basselin, M; Bell, JM; Lee, HJ; Rapoport, SI; Villacreses, NE1
Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E1
De la Cruz, JP; Gonzalez-Correa, JA; Jebrouni, N; Lopez-Villodres, JA; Reyes, JJ; Ruiz-Moreno, MI1
Chai, XQ; Chen, KZ; Ma, J; Wang, D; Xie, YH1

Trials

7 trial(s) available for flurbiprofen and thromboxane b2

ArticleYear
Flurbiprofen effect on gingival crevicular fluid prostaglandin and thromboxane levels in humans.
    Journal of periodontal research, 1992, Volume: 27, Issue:5

    Topics: Cross-Sectional Studies; Dinoprostone; Double-Blind Method; Female; Flurbiprofen; Gingival Crevicular Fluid; Humans; Longitudinal Studies; Male; Middle Aged; Periodontitis; Thromboxane B2

1992
The pharmacokinetics of flurbiprofen in younger and elderly patients with rheumatoid arthritis.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Weight; Female; Flurbiprofen; Humans; Male; Metabolic Clearance Rate; Middle Aged; Prospective Studies; Thromboxane B2

1992
The influence of cyclooxygenase inhibition on the loss of bronchoconstrictor response to repeated bradykinin challenge in asthma.
    The European respiratory journal, 1990, Volume: 3, Issue:8

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstriction; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flurbiprofen; Forced Expiratory Volume; Humans; Male; Random Allocation; Thromboxane B2

1990
Effects of nonsteroidal anti-inflammatory drugs on the bronchial hyperresponsiveness of middle-aged male smokers.
    The European respiratory journal, 1990, Volume: 3, Issue:8

    Topics: Aged; Airway Resistance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Flurbiprofen; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; Smoking; Thromboxane B2

1990
Flurbiprofen in the prevention and treatment of experimental gingivitis.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:10

    Topics: Adult; Dinoprostone; Female; Flurbiprofen; Gingival Crevicular Fluid; Gingivitis; Humans; Leukotriene B4; Thromboxane B2

1993
Disposition and effects of flurbiprofen enantiomers in human serum and blister fluid.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Blister; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Male; Reference Values; Stereoisomerism; Thromboxane B2

1997
Flurbiprofen axetil increases arterial oxygen partial pressure by decreasing intrapulmonary shunt in patients undergoing one-lung ventilation.
    Journal of anesthesia, 2015, Volume: 29, Issue:6

    Topics: Aged; Blood Gas Analysis; Female; Flurbiprofen; Humans; Lung; Male; Middle Aged; One-Lung Ventilation; Oxygen; Partial Pressure; Thromboxane B2

2015

Other Studies

17 other study(ies) available for flurbiprofen and thromboxane b2

ArticleYear
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Effects of NSAIDs on beagle crevicular cyclooxygenase metabolites and periodontal bone loss.
    Journal of periodontal research, 1992, Volume: 27, Issue:3

    Topics: Administration, Oral; Administration, Topical; Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Flurbiprofen; Gingival Crevicular Fluid; Ibuprofen; Naproxen; Prostaglandins F; Thromboxane B2

1992
Effects of pure enantiomers of flurbiprofen in comparison to racemic flurbiprofen on eicosanoid release from various rat organs ex vivo.
    Prostaglandins, 1991, Volume: 42, Issue:6

    Topics: Animals; Arachidonic Acid; Brain; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprost; Eicosanoids; Flurbiprofen; Gastric Mucosa; Jejunum; Lung; Rats; SRS-A; Stereoisomerism; Thromboxane B2

1991
Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury.
    The American review of respiratory disease, 1991, Volume: 143, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprost; Flurbiprofen; Hydrogen Peroxide; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Inbred Strains; Reperfusion Injury; Thromboxane B2; Thromboxane-A Synthase

1991
Influence of inhibitors of eicosanoid metabolism on proliferation of rat hepatoma cells and on tumor-host interaction.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 39, Issue:4

    Topics: Acrylates; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Liver Neoplasms, Experimental; Male; Methacrylates; Rats; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured

1990
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
    Journal of immunology (Baltimore, Md. : 1950), 1990, May-01, Volume: 144, Issue:9

    Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles

1990
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.
    The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Adenosine Triphosphate; Adult; Anemia, Sickle Cell; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Blood Vessels; Cell Adhesion; Cells, Cultured; Cyclooxygenase Inhibitors; Diabetes Mellitus; Endothelium; Epoprostenol; Erythrocytes; Fibrinogen; Flurbiprofen; Humans; Leukocytes; Middle Aged; Plasma; Prostaglandins F; Thromboxane B2

1986
Potentiation of adrenaline-induced platelet aggregation by angiotensin II.
    Thrombosis and haemostasis, 1985, Oct-30, Volume: 54, Issue:3

    Topics: Angiotensin II; Blood Platelets; Calcium; Cytoplasm; Drug Synergism; Epinephrine; Flurbiprofen; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Receptors, Angiotensin; Thromboxane B2

1985
Studies on the control of prostaglandin production by the hypothalamus in relation to LH release in the rat.
    The Journal of endocrinology, 1984, Volume: 103, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Castration; Circadian Rhythm; Dinoprost; Dinoprostone; Estradiol; Estrus; Female; Flurbiprofen; Hypothalamus; Luteinizing Hormone; Median Eminence; Norepinephrine; Pregnancy; Preoptic Area; Progesterone; Prostaglandins; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2

1984
[Effects of flurbiprofen on the platelet function in patients with ischemic cardiopathy].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:10

    Topics: Adult; Blood Platelets; Coronary Disease; Female; Flurbiprofen; Humans; Male; Middle Aged; Platelet Factor 4; Propionates; Prostaglandins F; Thromboxane B2

1982
[Effects of flurbiprofen on platelet function in patients with ischemic cardiomyopathy].
    Cardiologia (Rome, Italy), 1982, Volume: 27, Issue:10

    Topics: Adult; Blood Platelets; Coronary Disease; Female; Flurbiprofen; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Propionates; Thrombin; Thromboxane B2

1982
Isoprenaline inhibits thromboxane B2 release from U937 cells.
    Journal of leukocyte biology, 1993, Volume: 53, Issue:5

    Topics: Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Isoproterenol; Leukemia, Monocytic, Acute; Macrophages; Opsonin Proteins; Propranolol; Receptors, Adrenergic, beta; Thromboxane B2; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Zymosan

1993
Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases.
    European journal of pharmacology, 1996, Nov-28, Volume: 316, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Drug Stability; Female; Flurbiprofen; Humans; Isoenzymes; Leukocytes, Mononuclear; Male; Middle Aged; Thromboxane B2

1996
Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Escherichia coli; Flurbiprofen; Humans; Isoenzymes; Lipopolysaccharides; Meloxicam; Membrane Proteins; Monocytes; Ophthalmic Solutions; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thiazines; Thiazoles; Thromboxane B2

2000
Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats.
    Neurochemical research, 2007, Volume: 32, Issue:11

    Topics: Animals; Arachidonic Acid; Arecoline; Brain; Dinoprostone; Fatty Acids, Nonesterified; Flurbiprofen; Male; Phospholipases A2; Rats; Rats, Inbred F344; Signal Transduction; Thromboxane B2; Wakefulness

2007
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2

    Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2

2008
Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood.
    Anesthesia and analgesia, 2010, Volume: 111, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Humans; Ibuprofen; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2

2010