flurbiprofen and piroxicam

flurbiprofen has been researched along with piroxicam in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (19.51)	18.7374
1990's	6 (14.63)	18.2507
2000's	12 (29.27)	29.6817
2010's	15 (36.59)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Cihlar, T; Ho, ES; Mulato, AS	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Carrupt, PA; Martel, S; Ottaviani, G	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Kumar, M; Sinha, VR; Thareja, S	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Gąsiorowski, K; Gębarowski, T; Gębczak, K; Malinka, W; Strzelecka, M; Świątek, P; Urniaz, R	1
Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Xu, R; Yang, J; Zhang, X	1
Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Tian, C; Yang, Z	1
Deng, Y; He, Y; Li, W; Liu, H; Qiang, X; Song, Q; Tan, Z; Ye, C	1
Cheung, DT; Cobble, S; Nimni, ME; Schonfeld, SE; Yazdi, M	1
Gupta, SK; Joshi, S	1
Fall, PM; Raisz, LG; Simmons, HA	1
Kirino, T; Nakagomi, T; Noguchi, M; Saito, I; Sasaki, T; Takakura, K; Tamura, A	1
Kendall, MJ; Wilkins, MR; Woods, KL	1
Albengres, E; Cuny, M; Moritz, S; Piacentino, A; Revuz, J; Roujeau, JC; Touraine, R	1
Bradbrook, ID; Morrison, PJ; Rogers, HJ; Spector, RG	1
Banović, D; Nesović, B	1
Baumüller, A; Esders, K	1
Rosenthal, M	1
Bradley, JD; Brater, DC; Greene, PK; Tracy, TS; Worster, T	1
Lee, DA; Nguyen, KD	1
Ritchie, LD	1
Hauer, MJ; Hutzler, JM; Tracy, TS	1
Dickmann, LJ; Haining, RL; Hummel, MA; Hutzler, JM; Rettie, AE; Tracy, TS	1
Ferro, M; Pignatello, R; Puglisi, G	1
Hartnell, NR; Wilson, JP	1
Kaminski, NE; Rockwell, CE	1
Gorman, LA; Kumar, V; Rock, DA; Tracy, TS; Wahlstrom, JL; Warren, CJ	1
Eroğlu, CN; Kaplan, V	1

Reviews

2 review(s) available for flurbiprofen and piroxicam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract]. Fortschritte der Medizin, 1984, Dec-06, Volume: 102, Issue:45 Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases	1984

Trials

6 trial(s) available for flurbiprofen and piroxicam

Article	Year
The effects of selective and non-selective inhibition of cyclo-oxygenase on frusemide-stimulated natriuresis. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:2 Topics: Adult; Creatinine; Cyclooxygenase Inhibitors; Flurbiprofen; Furosemide; Humans; Indomethacin; Male; Natriuresis; Piroxicam; Stimulation, Chemical; Sulindac; Thiazines	1986
[Comparative study of piroxicam and flurbiprofen in the therapy of osteoarthrosis]. Medicinski pregled, 1983, Volume: 36, Issue:3-4 Topics: Adult; Aged; Anti-Inflammatory Agents; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Osteoarthritis; Piroxicam; Propionates; Thiazines	1983
The efficacy of flurbiprofen versus piroxicam in the treatment of acute soft tissue rheumatism. Current medical research and opinion, 1984, Volume: 9, Issue:5 Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Female; Flurbiprofen; Gastrointestinal Diseases; Humans; Male; Middle Aged; Periarthritis; Piroxicam; Propionates; Random Allocation; Tennis Elbow; Thiazines; Time Factors	1984
Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis. British journal of clinical pharmacology, 1994, Volume: 37, Issue:5 Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Drug Interactions; Drug Therapy, Combination; Female; Fluorescence Polarization Immunoassay; Flurbiprofen; Humans; Ketoprofen; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Piroxicam	1994
A clinical evaluation of flurbiprofen LAT and piroxicam gel: a multicentre study in general practice. Clinical rheumatology, 1996, Volume: 15, Issue:3 Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Family Practice; Female; Flurbiprofen; Gels; Humans; Male; Middle Aged; Piroxicam; Prospective Studies; Rheumatic Diseases	1996
Comparison of the Effects of Daily Single-Dose Use of Flurbiprofen, Diclofenac Sodium, and Tenoxicam on Postoperative Pain, Swelling, and Trismus: A Randomized Double-Blind Study. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:10 Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Edema; Female; Flurbiprofen; Humans; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Piroxicam; Tooth, Impacted; Treatment Outcome; Trismus	2016

Other Studies

33 other study(ies) available for flurbiprofen and piroxicam

Article	Year
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1 Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Synthesis, COX-1/2 inhibition activities and molecular docking study of isothiazolopyridine derivatives. Bioorganic & medicinal chemistry, 2017, 01-01, Volume: 25, Issue:1 Topics: Animals; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Meloxicam; Mice; Molecular Docking Simulation; Piroxicam; Pyridines; Quantitative Structure-Activity Relationship; Thiazines; Thiazoles	2017
Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment. Bioorganic & medicinal chemistry, 2018, 03-01, Volume: 26, Issue:5 Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Line; Cell Survival; Chalcones; Chelating Agents; Copper; Drug Design; Flurbiprofen; Humans; Lipopolysaccharides; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitric Oxide; Peptide Fragments; Recombinant Proteins; Structure-Activity Relationship	2018
Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease. Bioorganic & medicinal chemistry, 2018, 12-15, Volume: 26, Issue:23-24 Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Butyrylcholinesterase; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Peptide Fragments; Phthalimides; Protein Aggregates; Structure-Activity Relationship	2018
Discovery of 4'-OH-flurbiprofen Mannich base derivatives as potential Alzheimer's disease treatment with multiple inhibitory activities. Bioorganic & medicinal chemistry, 2019, 03-15, Volume: 27, Issue:6 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Cholinesterase Inhibitors; Drug Design; Drug Discovery; Electrophorus; Flurbiprofen; Humans; Mannich Bases; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Rats; Swine	2019
Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation. Journal of periodontal research, 1992, Volume: 27, Issue:1 Topics: Acetaminophen; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Bone Matrix; Flurbiprofen; Indomethacin; Male; Osteogenesis; Piroxicam; Rats	1992
Relationship between aldose reductase inhibiting activity and anti-cataract action of various non-steroidal anti-inflammatory drugs. Developments in ophthalmology, 1991, Volume: 21 Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cataract; Flurbiprofen; Galactose; Lens, Crystalline; Naproxen; Ophthalmic Solutions; Piroxicam; Rats; Sulindac	1991
Biphasic effects of nonsteroidal anti-inflammatory drugs on prostaglandin production by cultured rat calvariae. Prostaglandins, 1989, Volume: 37, Issue:5 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Indomethacin; Piroxicam; Rats	1989
Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus. Stroke, 1989, Volume: 20, Issue:7 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Cell Survival; Cyclooxygenase Inhibitors; Flurbiprofen; Hippocampus; Lipoxygenase Inhibitors; Male; Neurons; Piroxicam; Pyrazoles; Quinones	1989
Lymphocyte transformation test in drug-induced toxic epidermal necrolysis. International archives of allergy and applied immunology, 1985, Volume: 78, Issue:1 Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dipyrone; Drug Combinations; Female; Flurbiprofen; Humans; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Oxyphenbutazone; Phenylbutyrates; Piroxicam; Propionates; Pyrazolones; Stevens-Johnson Syndrome; Sulfadiazine; Sulfamethoxazole; Thiazines; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1985
Comparative steady state pharmacokinetic study of piroxicam and flurbiprofen in normal subjects. European journal of rheumatology and inflammation, 1981, Volume: 4, Issue:3 Topics: Adult; Female; Flurbiprofen; Homeostasis; Humans; Male; Piroxicam; Reference Values	1981
In vitro evaluation of antiproliferative potential of topical cyclooxygenase inhibitors in human Tenon's fibroblasts. Experimental eye research, 1993, Volume: 57, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Connective Tissue; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Evaluation Studies as Topic; Eye; Fibroblasts; Flurbiprofen; Humans; Mitosis; Piroxicam; Suprofen	1993
Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:7 Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dapsone; Enzyme Activation; Flurbiprofen; Hydroxylation; Models, Chemical; Naproxen; Piroxicam; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity	2001
Polymorphic variants (CYP2C93 and CYP2C95) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4 Topics: Alleles; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Flurbiprofen; Humans; Kinetics; Mutation; Naproxen; Piroxicam; Polymorphism, Genetic; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity	2002
Preparation of solid dispersions of nonsteroidal anti-inflammatory drugs with acrylic polymers and studies on mechanisms of drug-polymer interactions. AAPS PharmSciTech, 2002, Volume: 3, Issue:2 Topics: Acrylic Resins; Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Artificial Organs; Calorimetry, Differential Scanning; Diflunisal; Digestive System; Emulsions; Flurbiprofen; Gastroenterology; Piroxicam; Spectroscopy, Fourier Transform Infrared; Tablets; X-Ray Diffraction	2002
Replication of the Weber effect using postmarketing adverse event reports voluntarily submitted to the United States Food and Drug Administration. Pharmacotherapy, 2004, Volume: 24, Issue:6 Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Diflunisal; Epidemiologic Measurements; Flurbiprofen; Humans; Incidence; Piroxicam; Retrospective Studies; Sulindac; Time Factors; United Kingdom; United States; United States Food and Drug Administration	2004
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Benzamides; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Female; Flurbiprofen; Interleukin-2; Isoenzymes; Mice; Nitrobenzenes; Piroxicam; Polyunsaturated Alkamides; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonamides	2004
CYP2C9 inhibition: impact of probe selection and pharmacogenetics on in vitro inhibition profiles. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:12 Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Diclofenac; Enzyme Inhibitors; Flurbiprofen; Genotype; In Vitro Techniques; Pharmacogenetics; Phenytoin; Piroxicam; Tolbutamide; Warfarin	2006