flurbiprofen and morphine

flurbiprofen has been researched along with morphine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's1 (5.26)18.2507
2000's8 (42.11)29.6817
2010's8 (42.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bucovaz, ET; Harris, J; Heilman, CJ; Morrison, JC; Sherrill, J; Wiser, WL1
De Lia, JE; Jolles, CJ; Rodman, KC1
Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R1
Ando, Y; Fujinaga, A; Fukusaki, M; Sumikawa, K; Tanabe, T; Terao, Y; Yamashita, K1
Kamimura, H; Mano, Y; Usui, T2
Cheng, X; Hao, J; Shao, Y; Wang, K; Yan, Z1
Liu, XY; Shen, JC; Sun, HL; Wang, Z; Yang, JJ; Zhang, MQ1
Guo, X; Ouyang, Z; Xiao, X; Zhang, Q1

Reviews

2 review(s) available for flurbiprofen and morphine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for flurbiprofen and morphine

ArticleYear
Comparative study of flurbiprofen and morphine for postsurgical gynecologic pain.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adult; Aged; Cesarean Section; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Flurbiprofen; Humans; Hysterectomy; Middle Aged; Morphine; Pain, Postoperative; Placebos; Propionates; Random Allocation

1986
Comparative efficacy of oral flurbiprofen, intramuscular morphine sulfate, and placebo in the treatment of gynecologic postoperative pain.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Adult; Cesarean Section; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Hysterectomy; Injections, Intramuscular; Laparotomy; Morphine; Ovariectomy; Pain, Postoperative; Placebos; Propionates; Random Allocation; Vagina

1986
Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery.
    Journal of anesthesia, 2006, Volume: 20, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Preoperative Care; Spinal Fusion

2006
Flurbiprofen improves dysfunction of T-lymphocyte subsets and natural killer cells in cancer patients receiving post-operative morphine analgesia.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:8

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Flurbiprofen; Humans; Killer Cells, Natural; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Stomach Neoplasms; T-Lymphocyte Subsets

2014

Other Studies

13 other study(ies) available for flurbiprofen and morphine

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:S1

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Injections, Intraventricular; Ketoprofen; Ketorolac; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Tolmetin; Tromethamine; Uric Acid

1998
Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dideoxynucleosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flurbiprofen; Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Liver; Mefenamic Acid; Metabolic Detoxication, Phase II; Microsomes, Liver; Morphine; Morphine Derivatives; Recombinant Proteins; Stereoisomerism; UDP-Glucuronosyltransferase 1A9; Zidovudine

2007
The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Catalysis; Enzyme Inhibitors; Estradiol; Flurbiprofen; Gemfibrozil; Glucuronosyltransferase; Glycosylation; Humans; Hypolipidemic Agents; Isoenzymes; Kinetics; Mefenamic Acid; Microsomes, Liver; Molecular Structure; Morphine; Propofol; Recombinant Proteins

2007
Intravenous flurbiprofen axetil to relieve cancer-related multiple breakthrough pain: a clinical study.
    Journal of palliative medicine, 2013, Volume: 16, Issue:2

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Breakthrough Pain; Case-Control Studies; Female; Flurbiprofen; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Neoplasms; Pain Measurement; Prospective Studies; Treatment Outcome

2013
Comparison of perioperative flurbiprofen axetil or celecoxib administration for pain management after total-knee arthroplasty: A retrospective study.
    Medicine, 2018, Volume: 97, Issue:37

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Celecoxib; Chi-Square Distribution; Female; Flurbiprofen; Humans; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Period; Retrospective Studies; Statistics, Nonparametric; Treatment Outcome; Walking

2018