flurbiprofen and meclofenamic acid

flurbiprofen has been researched along with meclofenamic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's5 (27.78)18.2507
2000's5 (27.78)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A1
Gozalbes, R; Pineda-Lucena, A1
Atwell, GJ; Brooke, DG; Denny, WA; Flanagan, JU; Hamilton, EJ; Heinrich, D; Jamieson, SM; Owen, PJ; Raynham, T; Rigoreau, LJ; Samlal, SS; Schroeder, E; Silva, S; Soudy, C; Trivier, E; Turnbull, AP1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
van der Wal-Komproe, LE; van Duin, CT; van Miert, AS1
Lands, WE; Rome, LH1
Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC1
Lerner, UH; Ljunggren, O; Modéer, T1
Molskness, TA; Sargent, EL; Stouffer, RL; Zelinski-Wooten, MB1
Kulmacz, RJ; Lands, WE1
Ouellet, M; Percival, MD1
Lozano, JJ; Pouplana, R; Ruiz, J1
Das, P; Eriksen, JL; Golde, TE; Jessing, KW; Koo, EH; McLendon, DC; Ozols, VV; Sagi, SA; Smith, TE; Weggen, S; Zavitz, KH1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y1

Reviews

1 review(s) available for flurbiprofen and meclofenamic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for flurbiprofen and meclofenamic acid

ArticleYear
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis

1999
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship

2009
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3.
    Journal of medicinal chemistry, 2012, Sep-13, Volume: 55, Issue:17

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Benzoates; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Models, Molecular; Structure-Activity Relationship

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Effects of antipyretic agents on fever and ruminal stasis induced by endotoxins in conscious goats.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Body Temperature; Dipyrone; Drug Interactions; Endotoxins; Escherichia coli; Female; Flurbiprofen; Gastrointestinal Motility; Goats; Heart Rate; Male; Meclofenamic Acid; Phenylbutazone; Pressure; Rumen; Salmonella typhimurium; Time Factors

1977
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:12

    Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship

1975
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
    Agents and actions, 1990, Volume: 29, Issue:3-4

    Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E

1990
Bradykinin-2 receptor-mediated release of 3H-arachidonic acid and formation of prostaglandin E2 in human gingival fibroblasts.
    Journal of periodontal research, 1990, Volume: 25, Issue:6

    Topics: Analysis of Variance; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cells, Cultured; Child; Dinoprostone; Fibroblasts; Flurbiprofen; Gingiva; Humans; Indomethacin; Kallidin; Meclofenamic Acid; Receptors, Bradykinin; Receptors, Neurotransmitter

1990
Disparate effects of the prostaglandin synthesis inhibitors, meclofenamate, and flurbiprofen on monkey luteal tissue in vitro.
    Endocrinology, 1990, Volume: 126, Issue:3

    Topics: Adenylyl Cyclases; Animals; Corpus Luteum; Female; Flurbiprofen; Luteal Phase; Macaca mulatta; Meclofenamic Acid; ortho-Aminobenzoates; Progesterone; Prostaglandin Antagonists; Prostaglandins

1990
Stoichiometry and kinetics of the interaction of prostaglandin H synthase with anti-inflammatory agents.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Flurbiprofen; Indomethacin; Kinetics; Macromolecular Substances; Male; Meclofenamic Acid; ortho-Aminobenzoates; Oxygen Consumption; Propionates; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Seminal Vesicles; Sheep; Spectrophotometry

1985
Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms.
    The Biochemical journal, 1995, Feb-15, Volume: 306 ( Pt 1)

    Topics: Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Kinetics; Meclofenamic Acid; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sulfonamides

1995
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Journal of molecular graphics & modelling, 2002, Volume: 20, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides

2002
NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Brain; Cell Line; Endopeptidases; Female; Flurbiprofen; Humans; Meclofenamic Acid; Mice; Mice, Transgenic; Peptide Fragments; Protease Inhibitors; Stereoisomerism

2003
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin

2012