flurbiprofen and ketorolac

flurbiprofen has been researched along with ketorolac in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (22.22)18.2507
2000's7 (25.93)29.6817
2010's10 (37.04)24.3611
2020's4 (14.81)2.80

Authors

AuthorsStudies
Bukasa, A; Giuliano, F; Mitchell, JA; Vane, JR; Vojnovic, I; Warner, TD1
Topliss, JG; Yoshida, F1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Jolivette, LJ; Nagilla, R; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Kumar, M; Sinha, VR; Thareja, S1
Bellman, K; Knegtel, RM; Settimo, L1
Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Cabré, F; Carabaza, A; García, ML; Gómez, M; Gutiérrez, M; Mauleón, D; Rotllan, E1
Cabré, F; Díaz, I; Fernández-Guasti, A; López-Muñoz, FJ; Mauleón, D; Tost, D; Ventura, R1
Fowler, CJ; Janson, U; Johnson, RM; Norström, K; Stenström, A; Tiger, G; Wahlström, G1
Browne, GS; Day, RO; Ellis, BA; Nelson, C; Nguyen, T; Williams, KM1
Borodkin, MJ; McDonald, MB; Ocmand, A; Shoelson, B; Thompson, H; Wyse, TB1
Aragona, P; Ferreri, G; Laganà, E; Spinella, R; Tripodi, G1
Herrinton, LJ; Liu, L; Shorstein, NH; Waxman, MD1
Hernández-Camarena, JC; López-Jaime, GR; Nava-García, JA; Rodríguez-García, A1
Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y1
Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC1
Aiello, F; Balzano, F; Nazzi, S; Picchi, C; Recchimurzo, A; Uccello-Barretta, G1
Boisselier, E; Loiseau, A; Maranda, C; Poliquin, A; Raiche-Marcoux, G1
Allbaugh, RA; Terhaar, HM; Van Vertloo, LR; Viall, AK1

Reviews

3 review(s) available for flurbiprofen and ketorolac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
    The Cochrane database of systematic reviews, 2017, 05-18, Volume: 5

    Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flurbiprofen; Humans; Indomethacin; Ketorolac; Pain Measurement; Randomized Controlled Trials as Topic; Wound Healing

2017
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
    Paediatric drugs, 2022, Volume: 24, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain

2022

Trials

2 trial(s) available for flurbiprofen and ketorolac

ArticleYear
Comparison of the effectiveness of 4 anti-inflammatory drops in relieving photophobia after pupil dilation.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Flurbiprofen; Follow-Up Studies; Humans; Ketorolac; Light; Mydriatics; Ophthalmic Solutions; Prednisolone; Prospective Studies; Pupil; Tolmetin; Treatment Outcome; Vision Disorders

1999
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
    Eye (London, England), 2000, Volume: 14 ( Pt 2)

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; Epithelium, Corneal; Female; Flurbiprofen; Humans; Indomethacin; Ketorolac; Male; Middle Aged; Paresthesia; Procaine

2000

Other Studies

22 other study(ies) available for flurbiprofen and ketorolac

ArticleYear
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jun-22, Volume: 96, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Digestive System; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
    Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
    ACS chemical biology, 2014, Nov-21, Volume: 9, Issue:11

    Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Stereoselective inhibition of inducible cyclooxygenase by chiral nonsteroidal antiinflammatory drugs.
    Journal of clinical pharmacology, 1996, Volume: 36, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Guinea Pigs; Humans; Isoenzymes; Ketoprofen; Ketorolac; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Sheep; Stereoisomerism; Tolmetin

1996
Antinociceptive effects of S(+)-ketoprofen and other analgesic drugs in a rat model of pain induced by uric acid.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:S1

    Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Biotransformation; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Injections, Intraventricular; Ketoprofen; Ketorolac; Male; Morphine; Pain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Tolmetin; Tromethamine; Uric Acid

1998
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
    Archives of biochemistry and biophysics, 1999, Feb-15, Volume: 362, Issue:2

    Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, Drug; Endocannabinoids; Flurbiprofen; Glioma; Hydrolysis; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Kinetics; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors; Tolmetin; Tumor Cells, Cultured

1999
Stereoselective and substrate-dependent inhibition of hepatic mitochondria beta-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and ketorolac.
    Biochemical pharmacology, 1999, Apr-01, Volume: 57, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coenzyme A; Flurbiprofen; Ibuprofen; Ketorolac; Lipid Metabolism; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Stereoisomerism; Tolmetin

1999
Comparative Effectiveness of Three Prophylactic Strategies to Prevent Clinical Macular Edema after Phacoemulsification Surgery.
    Ophthalmology, 2015, Volume: 122, Issue:12

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Glucocorticoids; Humans; Injections, Intraocular; Ketorolac; Lens Implantation, Intraocular; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prednisolone; Retrospective Studies; Treatment Outcome; Triamcinolone Acetonide; Visual Acuity

2015
Effect of Topical Nonsteroidal Anti-inflammatory Drugs on Pupillary Size During Uncomplicated Cataract Surgery.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2017, Apr-01, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Double-Blind Method; Female; Flurbiprofen; Follow-Up Studies; Humans; Intraoperative Period; Ketorolac; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Phenylacetates; Postoperative Complications; Prospective Studies; Treatment Outcome

2017
NMR Investigation of the Interaction of Three Non-Steroidal Anti-Inflammatory Drugs with Human Serum Albumin.
    Molecules (Basel, Switzerland), 2022, Oct-06, Volume: 27, Issue:19

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Diclofenac; Flurbiprofen; Humans; Ketorolac; Magnetic Resonance Spectroscopy; Protons; Serum Albumin, Human

2022
Parametric Drug Release Optimization of Anti-Inflammatory Drugs by Gold Nanoparticles for Topically Applied Ocular Therapy.
    International journal of molecular sciences, 2022, Dec-19, Volume: 23, Issue:24

    Topics: Anti-Inflammatory Agents; Cornea; Drug Delivery Systems; Drug Liberation; Flurbiprofen; Gold; Ketorolac; Metal Nanoparticles; Nanoparticles; Ophthalmic Solutions; Renal Dialysis

2022
Retrospective evaluation of the incidence of gastrointestinal bleeding in dogs receiving ophthalmic nonsteroidal anti-inflammatory drugs.
    Veterinary ophthalmology, 2023, Volume: 26, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dog Diseases; Dogs; Flurbiprofen; Gastrointestinal Hemorrhage; Glucocorticoids; Incidence; Ketorolac; Prednisone; Retrospective Studies

2023