flurbiprofen has been researched along with indomethacin in 201 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 95 (47.26) | 18.7374 |
| 1990's | 47 (23.38) | 18.2507 |
| 2000's | 33 (16.42) | 29.6817 |
| 2010's | 23 (11.44) | 24.3611 |
| 2020's | 3 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Caron, G; Ermondi, G | 1 |
| Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Blobaum, AL; Marnett, LJ | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Barlow, DJ; Ehrman, TM; Hylands, PJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Berthelot, DJ; Gijsen, HJ; Oehlrich, D | 1 |
| Abdul-Hay, S; Qin, Z; Schiefer, IT; Thatcher, GR; Vanni, M; Wang, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Atwell, GJ; Brooke, DG; Denny, WA; Flanagan, JU; Hamilton, EJ; Heinrich, D; Jamieson, SM; Owen, PJ; Raynham, T; Rigoreau, LJ; Samlal, SS; Schroeder, E; Silva, S; Soudy, C; Trivier, E; Turnbull, AP | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Collins, AJ; Crook, D; Rose, AJ | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 2 |
| Connor, NS; Ford-Hutchinson, AW; Oliver, AM; Smith, MJ; Walker, JR | 1 |
| Good, A; Mena, H | 1 |
| Siegmeth, W | 1 |
| Nozu, K | 1 |
| Cockbill, SR; Heptinstall, S; Taylor, PM | 1 |
| Baker, JW; Coombes, RC; Ford, HT; Gazet, JC; Nash, AG; Neville, AM; Powles, JT | 1 |
| Collins, A,; Crook, D | 1 |
| Good, AE; Mena, HR | 1 |
| Brewis, ID | 1 |
| Bulgen, DY; Hazleman, BL | 1 |
| Kruger, HH | 1 |
| Frank, O | 1 |
| Alphen, GW; Wilhelm, PB | 1 |
| Funakoshi, K; Honma, H; Nozu, K | 1 |
| Millar, JL; Powles, TJ | 1 |
| Haylor, J; Lote, CJ | 1 |
| Kudo, M; Ofuji, T; Okumura, M | 1 |
| Loizzi, P; Numo, R; Pipitone, V | 1 |
| Fitzpatrick, FA; Wynalda, MA | 1 |
| Ghosh, P; Horsburgh, BA; McKenzie, LS; Taylor, TK | 1 |
| Lands, WE; Rome, LH | 1 |
| Adams, SS; McCullough, KF; Nicholson, JS | 1 |
| Bhattacherjee, P; Jaramillo, A; Paterson, CA; Sonnenfeld, G | 1 |
| Babbedge, RC; Gaffen, Z; Hart, SL; Moore, PK; Morgan, CV; Wallace, P | 1 |
| Gower, DB; Kwan, TK; Lim, YT | 1 |
| Lerner, UH; Mellström, D | 1 |
| Asproudis, I; Kalogeropoulos, C; Loucatzicos, E; Petroutsos, G; Psilas, K | 1 |
| Cheung, DT; Cobble, S; Nimni, ME; Schonfeld, SE; Yazdi, M | 1 |
| Brater, DC; Greene, PK; Hall, SD; Manatunga, AK; Murray, MD | 1 |
| Doerrler, W; Feingold, KR; Grünfeld, C; Hardardóttir, I | 1 |
| Beati, D; Gennari, G; Ortelli, G; Stucchi, CA; Vignanelli, M | 1 |
| Boraschi, D; Dewhirst, FE; Lerner, UH; Ljunggren, O | 1 |
| Bolling, SF; Deeb, GM; Grum, CM; Ljungman, AG; Morganroth, ML | 1 |
| Fernandes, G; Flescher, E; Fossum, D; Gray, PJ; Harper, MJ; Talal, N | 1 |
| Kojima, M; Mori, Y; Nakamura, J; Sasaki, H; Shibasaki, J | 1 |
| Strobel, J | 1 |
| Seitz, W; Strobel, J; Tietze, K | 1 |
| Lerner, UH; Ljunggren, O; Modéer, T | 1 |
| Dada, VK; Garg, SP; Gupta, SK; Jain, AK; Mehta, MR; Sachdev, MS | 1 |
| Manning, PJ; O'Byrne, PM; Stevens, WH; Watson, RM | 1 |
| MacLennan, SJ; McGrath, JC; Whittle, MJ | 1 |
| Fall, PM; Raisz, LG; Simmons, HA | 1 |
| Camras, CB; Miranda, OC | 1 |
| Camras, CB; Podos, SM | 1 |
| Kash, RL; Regis-Pacheco, LF; Robin, JB; Schanzlin, DJ | 1 |
| Bodin, C; Bonne, C; Chastel, C; Colin, J; Jouppe, B; Malet, F | 1 |
| Masuda, K; Mishima, H; Miyake, K | 1 |
| Gimbel, HV | 1 |
| Gherezghiher, T; Koss, MC | 1 |
| Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Wechter, WJ; Williams, RC | 1 |
| Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Offenbacher, S; Wechter, WJ; Williams, RC | 1 |
| Aked, D; Foster, SJ; Howarth, A; McCormick, ME | 1 |
| Kendall, MJ; Wilkins, MR; Woods, KL | 1 |
| Foster, SJ; Howarth, A; McCormick, ME | 1 |
| Karmali, RA; Marsh, J | 2 |
| Fischer, SM; Fürstenberger, G; Marks, F; Slaga, TJ | 1 |
| Fujii, M; Matsumoto, M; Mori, T; Sawada, Y; Terai, H | 1 |
| Giroud, JP; Hakim, J; Perianin, A | 1 |
| Grbic, JT; Jordan, A; Mannick, JA; Rodrick, ML; Wood, JJ | 1 |
| de Jong, PE; de Zeeuw, D; Donker, AJ; Pratt, JJ; van der Hem, GK; Vriesendorp, R | 1 |
| Ibba, G; Perpignano, G; Uras, R | 1 |
| McGiff, JC; Quilley, CP; Quilley, J | 1 |
| Momma, K; Takao, A | 1 |
| Jeffery, PK; Rogers, DF | 1 |
| Crossley, MJ; Hunneyball, IM; Spowage, M | 1 |
| Bockman, RS; Kelley, DB; Weintraub, AS | 1 |
| Kulkarni, PS; Srinivasan, BD | 3 |
| Kulmacz, RJ; Lands, WE | 1 |
| diZerega, GS; Nakamura, RM; Shimanuki, T | 1 |
| Andries, R; Bourgain, RH; Braquet, P; Deby, C | 1 |
| Brinn, EL; Lamborn, KR; Lomen, PL; Turner, LF | 1 |
| Brinn, EL; Lamborn, KR; Lomen, PL; Sack, RL; Turner, LF; Winblad, MA | 1 |
| Buchanan, WW; Kassam, YB | 1 |
| Rampton, DS; Sladen, GE | 1 |
| Hawkey, CJ; Lo Casto, M | 1 |
| Meienberg, O; Orfei, R | 1 |
| Hertting, G; Knepel, W; Vlaskovska, M | 1 |
| Formelli, F; Mazzoni, A; Supino, R | 1 |
| Buck, AC | 1 |
| Hotchkiss, ML; Pollack, IP; Quigley, HA; Robin, AL | 1 |
| Baumüller, A; Esders, K | 1 |
| Buck, AC; Davies, RL; Leaker, B; Moffat, DB | 1 |
| Rose, GA; Shah, PJ | 1 |
| Aihara, H; Fujita, A; Muramatsu, M; Otomo, S; Tanaka, M | 1 |
| Giroud, JP; Hakim, J; Perianin, A; Roch-Arveiller, M | 2 |
| Buck, AC; Lote, CJ; Sampson, WF | 1 |
| Jawad, AM; Rogers, HJ | 1 |
| Rudland, PS; Tsao, SW; Twiston Davies, AC | 1 |
| Benvenuti, C; Longoni, A; Viara, M | 1 |
| Andries, R; Bourgain, RH; Six, F | 1 |
| Aizawa, Y; Hasegawa, N; Inazu, N; Kogo, H; Takeuchi, K; Yamada, K; Yoshida, Y | 1 |
| Ghosh, P; Taylor, TK | 1 |
| Whittle, BJ | 1 |
| Bito, LZ; Klein, EM | 1 |
| Förstermann, U; Heldt, R; Hertting, G; Knappen, F | 1 |
| Burvenich, C; Peeters, G | 1 |
| Bhattacherjee, P; Eakins, KE; Williams, RN | 1 |
| De Moor, M; Ooghe, R | 1 |
| Hind, ID; Lloyd-Jones, JK; Rudge, SR | 1 |
| Bennett, A; Berstock, DA; Carroll, MA | 1 |
| Glasius, E; Noach, EL; Oosterhuis, JA; van Delft, JL; van Haeringen, NJ | 1 |
| Cooling, MJ; Sim, MF | 1 |
| Frank, GJ; Millar, JL; Powles, TJ | 1 |
| Sutcliffe, RL | 1 |
| Galasko, CS; Lacey, E; Rushton, S; Samuel, AW | 1 |
| Fischer, SM; Gleason, GL; Mills, GD; Slaga, TJ | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Solomon, LD | 1 |
| Abelson, M; Cheetham, JK; DeGryse, RE; Ginsburg, AP | 1 |
| Ouellet, M; Percival, MD | 1 |
| Goethals, M; Missotten, L | 1 |
| Bennett, J; Delamere, F; Holland, E; Knox, A; Patel, S; Pavord, I | 1 |
| Chai, JY; Kizior, MJ; Stern, PH; Turner, DW | 1 |
| Allaire, C; Bazin, R; Lablache Combier, M; Trinquand, C | 1 |
| Gomolin, JE; Koenekoop, RK | 1 |
| McGrath, JC; Smith, GC | 1 |
| Beck, WS; Brune, K; Geisslinger, G; Menzel-Soglowek, S | 1 |
| Howell, TH; Williams, RC | 1 |
| Bonewald, LF; Gallwitz, WE; Gaskell, SJ; Lee, CH; Mundy, GR; Qiao, M; Raftery, M; Roodman, GD | 1 |
| Fournier, DJ; Statkevich, P; Sweeney, KR | 1 |
| Callan, OH; So, OY; Swinney, DC | 1 |
| Ekabo, O; Garavito, RM; Loll, PJ; Picot, D | 1 |
| Brunius, G; Modéer, T; Shinoda, K; Yucel-Lindberg, T | 1 |
| Hessemer, V; Jacobi, A; Schmitt, K | 1 |
| Cheetham, JK; DeGryse, R; Garcia, CG; Gimbel, H; Van Westenbrugge, J | 1 |
| Cooper, AL; Morris, ID; Roe, SY; Rothwell, NJ | 1 |
| Diestelhorst, M; Konen, W; Mester, U; Schmidl, B | 1 |
| Davies, NM; Jamali, F | 1 |
| Diestelhorst, M; Konen, W; Mester, U; Raj, PS; Schmidl, B | 1 |
| Belmonte, C; Chen, X; Gallar, J | 1 |
| Lau, HY; Stenton, GR | 1 |
| Lerner, UH; Ohlin, A; Rosenquist, JB; Sundqvist, G | 1 |
| Camras, CB; Toris, CB; Wang, YL; Yablonski, ME; Zhan, GL | 1 |
| Diab, N; Domage, G; Dray, F; Mace, JL; Raguenes-Nicol, C; Russo-Marie, F; Solito, E; Streichenberger, G | 1 |
| Chikazu, D; Hakeda, Y; Kawaguchi, H; Kumegawa, M; Nakamura, K | 1 |
| Aragona, P; Ferreri, G; Laganà, E; Spinella, R; Tripodi, G | 1 |
| Kulmacz, RJ; Osawa, Y; Tsai, AL; Vuletich, JL; Wu, G | 1 |
| Lozano, JJ; Pouplana, R; Ruiz, J | 1 |
| Kato, S; Kunikata, T; Miyazawa, T; Takeuchi, K; Tanaka, A | 1 |
| Corbett, L; Knox, AJ; Nie, M; Pang, L | 1 |
| Kendall, DA; Randall, MD; Tep-areenan, P | 1 |
| Asai, T; Matsumoto, S; Murao, K; Shingu, K; Yamazaki, E | 1 |
| Bolla, M; Habib, A; Henrion, D; Levy, BI; Levy-Toledano, S; Loufrani, L; You, D | 1 |
| Fowler, CJ | 1 |
| Butcher, C; Evans, CE | 1 |
| Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P | 1 |
| Praticò, D; Townsend, KP | 1 |
| Kato, Y; Kubo, Y; Li, Q; Sai, Y; Tsuji, A; Tsuji, H | 1 |
| Mandula, H; Parepally, JM; Smith, QR | 1 |
| Takahira, Y; Takeuchi, K; Tanaka, A; Yokota, A | 1 |
| Cárdenas, S; Cruz-Vera, M; Lucena, R; Valcárcel, M | 1 |
| Adachi, S; Akema, T; Fujioka, H; Kakehashi, C; Matsuwaki, T; Nishihara, M | 1 |
| Chi, X; Tai, HH; Tong, M | 1 |
| Alcudia-León, MC; Cárdenas, S; Lucena, R; Riaño, S; Valcárcel, M | 1 |
| Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y | 1 |
| Dong, L; Jurban, BJ; Sharma, NP; Smith, WL | 1 |
| O'Sullivan, SE; Stanley, CP | 1 |
| Amayem, A; Brown, MD; Ghandour, O; Harrison, N; Lang, E; Lawrenson, AL; Lawrenson, JG; McCormick, R; Quirke, M; Wakai, A; Walsh, CD; Wang, Y | 1 |
| Boyd, KL; Goleniewska, K; Kita, H; Newcomb, DC; Norlander, AE; Peebles, RS; Toki, S; Wu, P; Zhang, J; Zhou, W | 1 |
| Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B | 1 |
| Hey-Hawkins, E; Kaluđerović, GN; Lönnecke, P; Morgan, I; Predarska, I; Saoud, M | 1 |
13 review(s) available for flurbiprofen and indomethacin
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Structural and functional basis of cyclooxygenase inhibition.
Topics: Animals; Cardiovascular System; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; Humans; Kinetics; Models, Molecular; Protein Conformation; Risk Assessment | 2007 |
γ-Secretase modulators as potential disease modifying anti-Alzheimer's drugs.
Topics: Alzheimer Disease; Amides; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cinnamates; Clinical Trials as Topic; Ginsenosides; Humans; Isoenzymes; Stereoisomerism | 2011 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The putative role of prostaglandins in surgical miosis.
Topics: Animals; Cataract Extraction; Ciliary Body; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Indomethacin; Iris; Ophthalmologic Surgical Procedures; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pupil; Rabbits | 1989 |
The role of endogenous prostaglandins in clinically-used and investigational glaucoma therapy.
Topics: Animals; Cyclooxygenase Inhibitors; Flurbiprofen; Glaucoma; Humans; Indomethacin; Intraocular Pressure; Laser Therapy; Macaca; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits | 1989 |
The putative role of prostaglandins in cystoid macular edema.
Topics: Aqueous Humor; Cataract Extraction; Diclofenac; Fluorescein Angiography; Flurbiprofen; Humans; Indomethacin; Macular Edema; Prostaglandins | 1989 |
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract].
Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases | 1984 |
Nonsteroidal antiinflammatory drugs as inhibitors of periodontal disease progression.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Inflammation; Periodontal Diseases; Prostaglandin Antagonists; Prostaglandins | 1993 |
Possible involvement of the endocannabinoid system in the actions of three clinically used drugs.
Topics: Anesthetics, Intravenous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Modulators; Drug Interactions; Endocannabinoids; Flurbiprofen; Indomethacin; Mice; Propofol; Receptors, Cannabinoid | 2004 |
Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Inflammation; Models, Biological; Models, Chemical; Models, Genetic; NF-kappa B; Peptides; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Prostaglandin-Endoperoxide Synthases | 2005 |
Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Kinetics; Lung Neoplasms; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Signal Transduction; Sulindac; Tissue Inhibitor of Metalloproteinase-1; Up-Regulation | 2011 |
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Corneal Injuries; Diclofenac; Flurbiprofen; Humans; Indomethacin; Ketorolac; Pain Measurement; Randomized Controlled Trials as Topic; Wound Healing | 2017 |
37 trial(s) available for flurbiprofen and indomethacin
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
Treatment of ankylosing spondylitis with flurbiprofen and indomethacin.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Male; Palliative Care; Propionates; Spondylitis, Ankylosing | 1977 |
A comparative study of flurbiprofen and indomethacin in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Joints; Male; Middle Aged; Palliative Care; Propionates | 1977 |
Management of ankylosing spondylitis with flurbiprofen or indomethacin.
Topics: Adult; Clinical Trials as Topic; Drug Tolerance; Flurbiprofen; Humans; Indomethacin; Propionates; Spondylitis, Ankylosing | 1977 |
A comparative study of flurbiprofen and indomethacin in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Propionates | 1977 |
A comparative study of the long-term efficacy of flurbiprofen and indomethacin in the treatment of rheumatoid arthritis, with special reference to iron metabolism.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Iron; Joints; Male; Middle Aged; Propionates | 1977 |
Flurbiprofen and indomethacin in the treatment of rheumatoid arthritis: a double-blind crossover study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Propionates | 1977 |
A double-blind comparative study of 150 mg flurbiprofen daily and 75 mg indomethacin daily in the treatment of osteoarthrosis of the hip joint.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Hip Joint; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Propionates | 1977 |
Flurbiprofen in rheumatoid arthritis therapy.
Topics: Animals; Arthritis, Rheumatoid; Female; Flurbiprofen; Humans; Indomethacin; Inflammation; Male; Propionates; Rats | 1977 |
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Fluorobenzenes; Flurbiprofen; Humans; Indomethacin; Mefenamic Acid; Pain; Phenylpropionates; Placebos; Prednisone; Propionates | 1975 |
The effect of indomethacin, diclofenac and flurbiprofen on the maintenance of mydriasis during extracapsular cataract extraction.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Diclofenac; Flurbiprofen; Humans; Indomethacin; Intraoperative Complications; Lens Capsule, Crystalline; Middle Aged; Miosis; Ophthalmic Solutions; Premedication; Pupil; Treatment Outcome | 1992 |
Effects of flurbiprofen on renal function in patients with moderate renal insufficiency.
Topics: Aged; Blood Pressure; Body Weight; Female; Flurbiprofen; Hemodynamics; Humans; Indomethacin; Kidney; Kidney Diseases; Male; Middle Aged; Sodium | 1992 |
[Comparison of the anti-miotic effect of 0.03% flurbiprofen with 1% indomethacin in cataract extraction].
Topics: Aged; Cataract Extraction; Double-Blind Method; Flurbiprofen; Humans; Indomethacin; Miotics; Premedication; Prospective Studies; Pupil | 1991 |
[Concentration of non-steroidal, anti-inflammatory topical agents in the aqueous humor].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Cornea; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Prospective Studies | 1991 |
[Quantitative studies of protein and cell concentrations in the anterior chamber in cataract surgery with therapy using steroidal and non-steroidal antiphlogistic drugs].
Topics: Anterior Chamber; Cell Count; Double-Blind Method; Endophthalmitis; Eye Proteins; Female; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Male; Ophthalmic Solutions; Postoperative Complications; Premedication; Prospective Studies | 1991 |
Pupillary dilatation during cataract surgery--relative efficacy of indomethacin and flurbiprofen.
Topics: Cataract Extraction; Double-Blind Method; Drug Administration Routes; Eye Color; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Prospective Studies; Pupil | 1990 |
Tachyphylaxis to inhaled methacholine in normal but not asthmatic subjects.
Topics: Administration, Inhalation; Adult; Asthma; Bronchodilator Agents; Female; Flurbiprofen; Forced Expiratory Volume; Humans; Indomethacin; Male; Methacholine Compounds; Middle Aged; Respiratory Function Tests; Tachyphylaxis | 1990 |
The effect of treatment with topical nonsteroidal anti-inflammatory drugs with and without intraoperative epinephrine on the maintenance of mydriasis during cataract surgery.
Topics: Administration, Topical; Cataract Extraction; Drug Therapy, Combination; Epinephrine; Flurbiprofen; Humans; Indomethacin; Intraoperative Care; Preoperative Care; Propionates; Pupil; Random Allocation | 1989 |
The effects of selective and non-selective inhibition of cyclo-oxygenase on frusemide-stimulated natriuresis.
Topics: Adult; Creatinine; Cyclooxygenase Inhibitors; Flurbiprofen; Furosemide; Humans; Indomethacin; Male; Natriuresis; Piroxicam; Stimulation, Chemical; Sulindac; Thiazines | 1986 |
[Double-blind cross-over comparison of flurbiprofen and indomethacin in osteoarthritis of the knee and hip].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Hip Joint; Humans; Indomethacin; Knee Joint; Male; Middle Aged; Osteoarthritis; Propionates; Random Allocation | 1986 |
Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with indomethacin.
Topics: Adolescent; Adult; Drug Evaluation; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Pain; Propionates; Spondylitis, Ankylosing | 1986 |
Renal prostaglandins and calcium excretion in urolithiasis.
Topics: Animals; Calcium; Clinical Trials as Topic; Flurbiprofen; Humans; Indomethacin; Kidney; Macaca fascicularis; Propionates; Prostaglandins; Rats; Urinary Calculi | 1983 |
Nonsteroidal anti-inflammatory agents after argon laser trabeculoplasty. A trial with flurbiprofen and indomethacin.
Topics: Adult; Aged; Argon; Clinical Trials as Topic; Double-Blind Method; Eye Diseases; Female; Flurbiprofen; Glaucoma; Humans; Indomethacin; Inflammation; Intraocular Pressure; Laser Therapy; Male; Methods; Middle Aged; Placebos; Postoperative Complications; Propionates; Random Allocation; Trabecular Meshwork | 1984 |
Anti-inflammatory drugs in management of spondylosis.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Lumbar Vertebrae; Male; Propionates; Spinal Osteophytosis | 1981 |
A double-blind comparison of flurbiprofen and indomethacin suppositories in the treatment of osteoarthrosis and rheumatoid disease.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Osteoarthritis; Propionates; Suppositories | 1981 |
Interaction between flurbiprofen and indomethacin in rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Flurbiprofen; Humans; Indomethacin; Infant; Propionates | 1982 |
Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema. Flurbiprofen-CME Study Group I.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cataract Extraction; Contrast Sensitivity; Double-Blind Method; Female; Flurbiprofen; Humans; Incidence; Indomethacin; Lenses, Intraocular; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Visual Acuity | 1995 |
Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cataract Extraction; Contrast Sensitivity; Double-Blind Method; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Macular Edema; Middle Aged; Ophthalmic Solutions; Vision, Ocular | 1995 |
Efficacy and safety of indomethacin 0.1% versus flurbiprofen 0.03% eyedrops in inflammation after argon laser trabeculoplasty. The Belgian Study Group on Glaucoma.
Topics: Double-Blind Method; Drug Tolerance; Endophthalmitis; Female; Flurbiprofen; Glaucoma, Open-Angle; Humans; Indomethacin; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Ophthalmic Solutions; Trabeculectomy | 1994 |
[Comparative efficacy of 0.1% indomethacin eyedrops, 0.03% flurbiprofen eyedrops and placebo for maintaining peroperative mydriasis].
Topics: Adult; Aged; Cataract Extraction; Double-Blind Method; Female; Flurbiprofen; Humans; Indomethacin; Intraoperative Period; Male; Middle Aged; Miosis; Mydriatics; Ophthalmic Solutions; Placebos; Premedication; Prospective Studies; Pupil | 1994 |
Presumed photic retinopathy after cataract surgery: an angiographic study.
Topics: Cataract Extraction; Fluorescein Angiography; Flurbiprofen; Follow-Up Studies; Fundus Oculi; Humans; Indomethacin; Infant, Newborn; Light; Macular Edema; Prevalence; Radiation Injuries; Retina; Retinal Diseases | 1993 |
[Anti-inflammatory effects and aqueous humor concentration of various nonsteroidal anti-inflammatory drugs in extracapsular cataract surgery].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Blood-Retinal Barrier; Cataract Extraction; Chromatography, High Pressure Liquid; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; Endophthalmitis; Female; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications | 1996 |
Intraocular availability and pupillary effect of flurbiprofen and indomethacin during cataract surgery.
Topics: Absorption; Adult; Aged; Aged, 80 and over; Aqueous Humor; Biological Availability; Cyclooxygenase Inhibitors; Double-Blind Method; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Middle Aged; Miosis; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Pupil | 1996 |
[Laser flare measurement with 3 different nonsteroidal anti-inflammatory drugs after phacoemulsification with posterior chamber lens implantation].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Endophthalmitis; Female; Flurbiprofen; Humans; Indomethacin; Lenses, Intraocular; Male; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies | 1997 |
Efficacy and tolerance of diclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Endophthalmitis; Female; Flurbiprofen; Follow-Up Studies; Humans; Indomethacin; Lenses, Intraocular; Male; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Treatment Outcome | 1996 |
The effects of the topical administration of non-steroidal anti-inflammatory drugs on corneal epithelium and corneal sensitivity in normal subjects.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diclofenac; Double-Blind Method; Epithelium, Corneal; Female; Flurbiprofen; Humans; Indomethacin; Ketorolac; Male; Middle Aged; Paresthesia; Procaine | 2000 |
[Comparison of analgesic effects of intravenous flurbprofen and suppository indomethacin after laparoscopic cholecystectomy].
Topics: Acute Disease; Adult; Aged; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Female; Flurbiprofen; Humans; Indomethacin; Infusions, Intravenous; Male; Middle Aged; Pain, Postoperative; Suppositories; Time Factors; Treatment Outcome | 2003 |
151 other study(ies) available for flurbiprofen and indomethacin
| Article | Year |
|---|---|
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.
Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Humans; Mice; Neurons; Nitrates; Small Molecule Libraries | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Benzoates; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Models, Molecular; Structure-Activity Relationship | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
A comparison of the effect of flurbiprofen on prostaglandin synthetase from human rheumatoid synovium and enzymatically active animal tissues.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Indomethacin; Kidney Medulla; Male; Mixed Function Oxygenases; Propionates; Rabbits; Seminal Vesicles; Synovial Membrane | 1976 |
Separate anti-inflammatory effects of indomethacin, flurbiprofen and benoxaprofen.
Topics: Animals; Benzoxazoles; Flurbiprofen; Indomethacin; Inflammation; Leukocytes; Propionates; Prostaglandins; Rats | 1977 |
Flurbiprofen: highly potent inhibitor of prostaglandin synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Ibuprofen; Indomethacin; Male; Microsomes; Oxygen Consumption; Phenylbutazone; Propionates; Prostaglandins E; Seminal Vesicles | 1978 |
A comparison of the abilities of acetylsalicylic acid, flurbiprofen and indomethacin to inhibit the release reaction and prostaglandin synthesis in human blood platelets.
Topics: Aspirin; Blood Platelets; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Propionates; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Time Factors | 1979 |
Agents affecting osteolysis in patients with breast cancer.
Topics: Anti-Inflammatory Agents; Aspirin; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcitonin; Female; Flurbiprofen; Humans; Indomethacin; Osteolysis; Plicamycin; Time Factors | 1979 |
Prostaglandin synthetase activity from human rheumatoid synovial tissue and its inhibition by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cattle; Depression, Chemical; Flurbiprofen; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Indomethacin; Kidney Medulla; Male; Microsomes; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Rabbits; Seminal Vesicles; Synovial Membrane | 1975 |
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Flurbiprofen; Ibuprofen; In Vitro Techniques; Indomethacin; Iris; Mixed Function Oxygenases; Muscle Contraction; Muscle, Smooth; Prostaglandins; Prostaglandins E; Prostaglandins F | 1977 |
[Effects of flurbiprofen and indomethacin on release of prostaglandin F 2 alpha from uterus and plasma levels of sex hormones during parturition in rats (author's transl)].
Topics: Animals; Corpus Luteum; Female; Flurbiprofen; Gonadal Steroid Hormones; In Vitro Techniques; Indomethacin; Isomerases; Labor, Obstetric; Pregnancy; Propionates; Prostaglandins F; Rats; Uterus | 1979 |
Non-steroidal anti-inflammatory drugs and cytotoxics.
Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Chlorambucil; Digestive System; Flurbiprofen; Indomethacin; Melphalan; Mice; Propionates; Rats | 1979 |
Absence of measurable changes in effective renal plasma flow and glomerular filtration rate in conscious rats after prostaglandin synthetase inhibition by indomethacin or flurbiprofen [proceedings].
Topics: Animals; Flurbiprofen; Glomerular Filtration Rate; Indomethacin; Kidney; Propionates; Rats | 1979 |
[Comparative studies on gastrointestinal damage induced by non-steroidal anti-inflammatory drugs in rats (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Male; Phenylbutazone; Rats; Stomach Ulcer | 1978 |
In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents.
Topics: Acetaminophen; Acetonitriles; Administration, Oral; Animals; Anti-Inflammatory Agents; Brain; Duodenum; Female; Flurbiprofen; Gastric Mucosa; Ibuprofen; Indomethacin; Intestine, Small; Kidney; Liver; Lung; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Time Factors | 1976 |
Effect of anti-inflammatory drugs on sulphated glycosaminoglycan synthesis in aged human articular cartilage.
Topics: Aged; Aging; Anti-Inflammatory Agents; Cartilage, Articular; Depression, Chemical; Flurbiprofen; Glycosaminoglycans; Humans; Hydrocortisone; Ibuprofen; In Vitro Techniques; Indomethacin; Middle Aged; Sodium Salicylate | 1976 |
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship | 1975 |
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Capillary Permeability; Codeine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythema; Female; Fever; Flurbiprofen; Guinea Pigs; Indomethacin; Inflammation; Liver Glycogen; Male; Mice; Phenylbutazone; Propionates; Rats; Spasm | 1975 |
Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation.
Topics: Animals; Antigens; Arrestin; Autoantibodies; Dinoprostone; Disease Models, Animal; Eye Proteins; Female; Flurbiprofen; Immunoglobulin G; Indomethacin; Injections, Subcutaneous; Leukotriene B4; Membrane Proteins; Neutrophils; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Uveitis | 1992 |
Synergistic anti-nociceptive effect of L-NG-nitro arginine methyl ester (L-NAME) and flurbiprofen in the mouse.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Blood Pressure; Drug Synergism; Flurbiprofen; Formaldehyde; Indomethacin; Male; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Pain | 1992 |
Effect of aspirin, flurbiprofen and indomethacin on porcine testicular steroidogenesis.
Topics: Animals; Aspirin; Chromatography, Gas; Flurbiprofen; Indomethacin; Male; Microsomes; Steroids; Swine; Testis; Testosterone | 1992 |
Caffeine has the capacity to stimulate calcium release in organ culture of neonatal mouse calvaria.
Topics: Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Caffeine; Calcium; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Mice; Organ Culture Techniques; Parathyroid Hormone; Theophylline | 1992 |
Effects of non-steroidal anti-inflammatory drugs on demineralized bone-induced bone formation.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Bone Matrix; Flurbiprofen; Indomethacin; Male; Osteogenesis; Piroxicam; Rats | 1992 |
Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism.
Topics: 3T3 Cells; Adipose Tissue; Animals; Cells, Cultured; Cytokines; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Interferon Type I; Interferon-gamma; Interleukin-1; Kinetics; Lipolysis; Lipoprotein Lipase; Mice; Prostaglandins; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Comparison of human interleukin-1 beta and its 163-171 peptide in bone resorption and the immune response.
Topics: Amino Acid Sequence; Animals; Antibody Formation; Bone and Bones; Bone Resorption; Bradykinin; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Interleukin-1; Interleukin-1beta; Kinetics; Mice; Mice, Inbred C3H; Molecular Sequence Data; Organ Culture Techniques; Peptide Fragments; Recombinant Proteins | 1991 |
Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprost; Flurbiprofen; Hydrogen Peroxide; Indomethacin; Lung; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Inbred Strains; Reperfusion Injury; Thromboxane B2; Thromboxane-A Synthase | 1991 |
Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Arachidonic Acids; Calcium; CD8 Antigens; Cell Division; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Drug Synergism; Female; Flow Cytometry; Flurbiprofen; Humans; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Radioimmunoassay; T-Lymphocytes | 1991 |
Enhancing effect of pyrrolidone derivatives on transdermal penetration of 5-fluorouracil, triamcinolone acetonide, indomethacin, and flurbiprofen.
Topics: Administration, Topical; Animals; Biological Availability; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Fluorouracil; Flurbiprofen; Indomethacin; Male; Myristates; Pyrrolidinones; Rats; Rats, Inbred Strains; Skin Absorption; Solubility; Triamcinolone Acetonide | 1991 |
Bradykinin-2 receptor-mediated release of 3H-arachidonic acid and formation of prostaglandin E2 in human gingival fibroblasts.
Topics: Analysis of Variance; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cells, Cultured; Child; Dinoprostone; Fibroblasts; Flurbiprofen; Gingiva; Humans; Indomethacin; Kallidin; Meclofenamic Acid; Receptors, Bradykinin; Receptors, Neurotransmitter | 1990 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aspirin; Calcium; Female; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Oxygen; Partial Pressure; Pregnancy; Propionates; Reference Values; Umbilical Arteries | 1988 |
Biphasic effects of nonsteroidal anti-inflammatory drugs on prostaglandin production by cultured rat calvariae.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Indomethacin; Piroxicam; Rats | 1989 |
The histopathology of corneal neovascularization. Inhibitor effects.
Topics: Animals; Chemotaxis, Leukocyte; Cornea; Corneal Injuries; Disease Models, Animal; Electrocoagulation; Female; Flurbiprofen; Indomethacin; Neovascularization, Pathologic; Neutrophils; Prednisolone; Propionates; Rabbits | 1985 |
[Experimental herpes simplex keratitis in rabbits. Evaluation of pro-infectious effects of topical non-steroidal anti-inflammatory agents].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation; Flurbiprofen; Indomethacin; Infections; Keratitis, Dendritic; Rabbits; Thiazoles; Time Factors | 1989 |
Argon laser-induced ocular hypertension: animal model of ocular inflammation.
Topics: Animals; Aqueous Humor; Argon; Disease Models, Animal; Endophthalmitis; Female; Flurbiprofen; Ganglia, Spinal; In Vitro Techniques; Indomethacin; Intraocular Pressure; Iris; Lasers; Light Coagulation; Male; Ocular Hypertension; Pupil; Rabbits | 1989 |
Indomethacin or flurbiprofen treatment of periodontitis in beagles: comparison of effect on bone loss.
Topics: Alveolar Process; Animals; Bone Resorption; Dogs; Female; Flurbiprofen; Indomethacin; Periodontal Diseases; Periodontitis; Propionates; Radiography | 1987 |
Indomethacin or flurbiprofen treatment of periodontitis in beagles: effect on crevicular fluid arachidonic acid metabolites compared with effect on alveolar bone loss.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bone Resorption; Cyclooxygenase Inhibitors; Dogs; Female; Flurbiprofen; Gingival Crevicular Fluid; Indomethacin; Longitudinal Studies; Periodontal Diseases; Propionates; Prostaglandin Antagonists; Radiography | 1988 |
Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B1.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Blood Proteins; Calcimycin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Skin | 1986 |
The contribution of cyclooxygenase and lipoxygenase products to acute inflammation in the rat.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Flurbiprofen; Indomethacin; Inflammation; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Rats | 1986 |
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
Topics: Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunization; Indomethacin; Mammary Neoplasms, Experimental; Prostaglandins E; Rats; Rats, Inbred F344 | 1986 |
Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; DNA Replication; Female; Flurbiprofen; Indomethacin; Mice; Ornithine Decarboxylase; Prostaglandins E; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
The properties of solid dispersions of indomethacin, ketoprofen and flurbiprofen in phosphatidylcholine.
Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Flurbiprofen; Indomethacin; Ketoprofen; Phenylpropionates; Phosphatidylcholines; Powders; Propionates | 1988 |
Differential in vivo effects of indomethacin, ibuprofen, and flurbiprofen on oxygen-dependent killing activities of neutrophils elicited by acute nonimmune inflammation in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Ibuprofen; Indomethacin; Inflammation; Male; Neutrophils; Oxygen; Phagocytosis; Rats; Rats, Inbred Strains | 1988 |
Suppression of interleukin 2 production in an animal model of thermal injury is related to prostaglandin synthesis.
Topics: Animals; Burns; Disease Models, Animal; Flurbiprofen; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Prostaglandins E; T-Lymphocytes | 1987 |
Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Flurbiprofen; Glomerular Filtration Rate; Humans; Indomethacin; Male; Middle Aged; Nephrotic Syndrome; Prostaglandins E; Proteinuria; Renin; Sulindac | 1986 |
Failure of chronic aspirin treatment to inhibit urinary prostaglandin excretion in spontaneously hypertensive rats: comparison with indomethacin and flurbiprofen.
Topics: Animals; Aspirin; Drug Administration Schedule; Flurbiprofen; Hypertension; Indomethacin; Kidney; Male; Propionates; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1987 |
In vivo constriction of the ductus arteriosus by nonsteroidal antiinflammatory drugs in near-term and preterm fetal rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Flurbiprofen; Gestational Age; Indomethacin; Pregnancy; Rats; Rats, Inbred Strains | 1987 |
Indomethacin and flurbiprofen speed recovery of rat bronchial epithelium after exposure to cigarette smoke.
Topics: Animals; Bronchi; Bronchitis; Epithelium; Flurbiprofen; Indomethacin; Male; Nicotiana; Plants, Toxic; Propionates; Rats; Rats, Inbred Strains; Smoke; Time Factors | 1986 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Flurbiprofen; Ibuprofen; Indomethacin; Joints; Leukocyte Count; Lymphocytes; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Prednisolone; Time Factors | 1986 |
Prostaglandin E2 induces receptive behaviors in female Xenopus laevis.
Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Indomethacin; Ovariectomy; Posture; Prostaglandins E; Rana pipiens; Reaction Time; Sexual Behavior, Animal; Xenopus laevis | 1985 |
Comparative in vivo inhibitory effects of nonsteroidal anti-inflammatory agents on prostaglandin synthesis in rabbit ocular tissues.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Conjunctiva; Dinoprostone; Flurbiprofen; Indomethacin; Injections, Intraperitoneal; Prostaglandins E; Rabbits; Uvea | 1985 |
Stoichiometry and kinetics of the interaction of prostaglandin H synthase with anti-inflammatory agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Flurbiprofen; Indomethacin; Kinetics; Macromolecular Substances; Male; Meclofenamic Acid; ortho-Aminobenzoates; Oxygen Consumption; Propionates; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Seminal Vesicles; Sheep; Spectrophotometry | 1985 |
In vivo modulation of leukotaxis by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Chemotaxis, Leukocyte; Female; Flurbiprofen; Ibuprofen; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Rabbits | 1985 |
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunotherapy; Indomethacin; Mammary Neoplasms, Experimental; Propionates; Prostaglandins E; Rats; Rats, Inbred F344 | 1985 |
The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Flurbiprofen; Indomethacin; Male; Mesenteric Arteries; Rats; Rats, Inbred Strains; Thrombosis | 1985 |
Flurbiprofen in the treatment of acute gout. A comparison with indomethacin.
Topics: Acute Disease; Arthritis; Drug Evaluation; Flurbiprofen; Gout; Humans; Indomethacin; Pain; Propionates | 1986 |
European experience with flurbiprofen. A new analgesic/anti-inflammatory agent.
Topics: Aspirin; Drug Evaluation; Europe; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Propionates | 1986 |
Relapse of ulcerative proctocolitis during treatment with non-steroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Colitis, Ulcerative; Female; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Recurrence; Salicylates | 1981 |
Inhibition of prostaglandin synthetase in human rectal mucosa.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis, Ulcerative; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Intestinal Mucosa; Mesalamine; Prednisolone; Rectum; Sulfapyridine; Sulfasalazine | 1983 |
Carotidynia: report of eight cases and prospective evaluation of therapy.
Topics: Adult; Aged; Carotid Artery Diseases; Dihydroergotamine; Female; Flurbiprofen; Humans; Indomethacin; Male; Methysergide; Middle Aged; Pain; Syndrome | 1983 |
Adrenocorticotropin and beta-endorphin release from rat adenohypophysis in vitro: inhibition by prostaglandin E2 formed locally in response to vasopressin and corticotropin-releasing factor.
Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Endorphins; Flurbiprofen; Indomethacin; Male; Pituitary Gland, Anterior; Potassium; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1984 |
Effect of medroxyprogesterone acetate and of some antiinflammatory agents on mouse erythroleukemia cell differentiation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Aspirin; Cell Differentiation; Cell Line; Dexamethasone; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flurbiprofen; Indomethacin; Leukemia, Erythroblastic, Acute; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Pyrazoles; Time Factors | 1984 |
Inhibition of experimental nephrocalcinosis with a prostaglandin synthetase inhibitor.
Topics: Animals; Calcium; Calcium Gluconate; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Indomethacin; Kidney; Nephrocalcinosis; Propionates; Rats; Rats, Inbred Strains | 1983 |
Prostaglandin synthetase inhibitors and their effect on urinary calcium excretion and other parameters in idiopathic hypercalciuria.
Topics: Adult; Calcium; Calcium, Dietary; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Indomethacin; Male; Propionates; Urinary Calculi | 1984 |
Time-dependent inhibition of prostaglandins synthesis by nonsteroidal antiinflammatory drugs; time-dependent alteration of inhibitory effect and characteristics of its active site.
Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Cattle; Cyclooxygenase Inhibitors; Drug Interactions; Flurbiprofen; In Vitro Techniques; Indomethacin; Kinetics; Male; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Salicylates; Salicylic Acid | 1984 |
In vivo interaction of nonsteroidal anti-inflammatory drugs on the locomotion of neutrophils elicited by acute non-specific inflammations in the rat--effect of indomethacin, ibuprofen and flurbiprofen.
Topics: Animals; Anti-Inflammatory Agents; Blood; Calcium Pyrophosphate; Chemotaxis, Leukocyte; Flurbiprofen; Ibuprofen; In Vitro Techniques; Indomethacin; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pleurisy; Rats; Rats, Inbred Strains | 1984 |
In vivo effects of indomethacin and flurbiprofen on the locomotion of neutrophils elicited by immune and non-immune inflammation in the rat.
Topics: Animals; Cell Movement; Flurbiprofen; Hypersensitivity; In Vitro Techniques; Indomethacin; Inflammation; Male; Neutrophils; Pleurisy; Propionates; Rats; Rats, Inbred Strains | 1984 |
The influence of renal prostaglandins on urinary calcium excretion in idiopathic urolithiasis.
Topics: Animals; Calcium; Dinoprostone; Flurbiprofen; Indomethacin; Kidney; Macaca fascicularis; Male; Potassium; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Urinary Calculi | 1983 |
The effects of flurbiprofen and indomethacin on the mitogenic response of human peripheral mononuclear cells.
Topics: Adult; Anti-Inflammatory Agents; Cell Count; Cell Survival; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Flurbiprofen; Humans; Indomethacin; Lymphocyte Activation; Male; Mitogens; Monocytes; Propionates; Prostaglandins E | 1984 |
Rat mammary preadipocytes in culture produce a trophic agent for mammary epithelia-prostaglandin E2.
Topics: Adipose Tissue; Animals; Cell Count; Cell Line; Cells, Cultured; Culture Media; Dinoprost; Dinoprostone; DNA Replication; Epithelial Cells; Female; Flurbiprofen; Indomethacin; Mammary Glands, Animal; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Steroid-sparing action of flurbiprofen and indomethacin in rheumatoid arthritis: a nine-week study.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Flurbiprofen; Humans; Indomethacin; Male; Middle Aged; Prednisone; Propionates | 1983 |
The action of cyclooxygenase and prostacyclin-synthetase inhibitors on platelet-vessel wall interaction.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Flurbiprofen; Indomethacin; Intramolecular Oxidoreductases; Male; Mesenteric Arteries; Perfusion; Prostaglandins; Rats | 1980 |
[Inhibitory action of non-steroidal anti-flammatory drugs on prostaglandin synthesis and release (author's transl)].
Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Depression, Chemical; Diclofenac; Flurbiprofen; Indomethacin; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Synovial Membrane; Synovitis; Thiazoles | 1980 |
Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Digestive System; Flurbiprofen; Gastric Mucosa; Indomethacin; Intestinal Mucosa; Ketoprofen; Naproxen; Prostaglandins; Rats | 1981 |
The role of the arachidonic acid cascade in the species-specific X-ray-induced inflammation of the rabbit eye.
Topics: Animals; Arachidonic Acids; Cromolyn Sodium; Endophthalmitis; Eye; Female; Flurbiprofen; Imidazoles; Indomethacin; Intraocular Pressure; Male; Prednisolone; Prostaglandins; Rabbits; Radiation Injuries, Experimental; Species Specificity; Vitamin E | 1982 |
Potential anticonvulsive properties of endogenous prostaglandins formed in mouse brain.
Topics: Animals; Brain; Diclofenac; Electroshock; Flurbiprofen; Indomethacin; Kinetics; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1982 |
Effect of prostaglandin synthetase inhibitors on mammary blood flow during experimentally induced mastitis in lactating goats.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Goats; Indomethacin; Lactation; Lipopolysaccharides; Mammary Glands, Animal; Mastitis; Pregnancy; Prostaglandin Antagonists; Regional Blood Flow | 1982 |
A comparison of the ocular anti-inflammatory activity of steroidal and nonsteroidal compounds in the rat.
Topics: Animals; Anti-Inflammatory Agents; Dexamethasone; Drug Evaluation, Preclinical; Eye Diseases; Flurbiprofen; Indomethacin; Inflammation; Propionates; Rats | 1983 |
Increased survival of cancer-bearing mice treated with inhibitors of prostaglandin synthesis alone or with chemotherapy.
Topics: Adenocarcinoma; Animals; Biological Availability; Body Weight; Drug Therapy, Combination; Female; Flurbiprofen; Indomethacin; Male; Mammary Neoplasms, Experimental; Melphalan; Methotrexate; Mice; Neoplasm Recurrence, Local; Propionates; Prostaglandin Antagonists | 1982 |
A comparison of the effects of non-steroidal compounds on the disruption of the blood-aqueous barrier.
Topics: Animals; Anti-Inflammatory Agents; Aqueous Humor; Diclofenac; Eye; Eye Proteins; Flurbiprofen; Hydrogen-Ion Concentration; Indomethacin; Rabbits | 1982 |
Reduction of the effects of diuretics or sodium chloride loading in the conscious rat by inhibitors of prostaglandin synthesis.
Topics: Acetazolamide; Amiloride; Animals; Bendroflumethiazide; Diuretics; Female; Flurbiprofen; Furosemide; Indomethacin; Natriuresis; Propionates; Rats; Rats, Inbred Strains; Sodium Chloride | 1982 |
The effect of steroidal and nonsteroidal anti-inflammatory agents on corneal re-epithelialization.
Topics: Animals; Anti-Inflammatory Agents; Cornea; Dexamethasone; Epithelium; Fluorometholone; Flurbiprofen; Indomethacin; Prednisolone; Rabbits | 1981 |
Polymorphonuclear leukocyte response. Inhibition following corneal epithelial denudation by steroidal and nonsteroidal anti-inflammatory agents.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Aspirin; Cornea; Dexamethasone; Epithelium; Fluorometholone; Flurbiprofen; Indomethacin; Male; Neutrophils; Prednisolone; Rabbits | 1981 |
Interactions of cytotoxic and anti-inflammatory agents on normal and neoplastic tissue.
Topics: Animals; Carcinoma 256, Walker; Cell Survival; Chlorambucil; Flurbiprofen; Hematopoietic Stem Cells; Indomethacin; Melphalan; Mice; Propionates | 1980 |
Indomethacin treatment of postural hypotension.
Topics: Aged; Flurbiprofen; Humans; Hypotension, Orthostatic; Indomethacin; Prostaglandins E | 1980 |
The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis.
Topics: Animals; Bone Resorption; Breast Neoplasms; Culture Techniques; Diphosphonates; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Mice; Neoplasms, Experimental; Osteolysis; Prostaglandin Antagonists | 1980 |
Indomethacin enhancement of TPA tumor promotion in mice.
Topics: Animals; Drug Synergism; Female; Flurbiprofen; Indomethacin; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms.
Topics: Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Kinetics; Meclofenamic Acid; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Sulfonamides | 1995 |
Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo-oxygenase inhibitors.
Topics: Animals; Aspirin; Bromodeoxyuridine; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Muscle, Smooth; Trachea | 1994 |
Flurbiprofen effects on bone resorption.
Topics: Analysis of Variance; Animals; Bone and Bones; Bone Resorption; Disease Models, Animal; Fetus; Flurbiprofen; Indomethacin; Prostaglandins E; Rats; Rats, Sprague-Dawley; Thyroxine | 1993 |
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents | 1993 |
R-flurbiprofen: isomeric ballast or active entity of the racemic compound?
Topics: Animals; Flurbiprofen; Indomethacin; Prostaglandins; Rats; Stereoisomerism | 1993 |
5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices.
Topics: Acid Phosphatase; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Bone Matrix; Bone Resorption; Chickens; Culture Media, Conditioned; Endopeptidases; Female; Flurbiprofen; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Osteoclasts; Tartrates; Ultraviolet Rays | 1993 |
Characterization of methotrexate elimination and interaction with indomethacin and flurbiprofen in the isolated perfused rat kidney.
Topics: Animals; Drug Interactions; Flurbiprofen; In Vitro Techniques; Indomethacin; Kidney; Male; Methotrexate; Perfusion; Proteins; Rats; Rats, Sprague-Dawley | 1993 |
The kinetic factors that determine the affinity and selectivity for slow binding inhibition of human prostaglandin H synthase 1 and 2 by indomethacin and flurbiprofen.
Topics: Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Kinetics; Mathematics; Models, Theoretical; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins; Time Factors | 1996 |
Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Cyclooxygenase Inhibitors; Flurbiprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Protein Structure, Secondary; Thiophenes | 1996 |
Effect of phenytoin on interleukin-1 beta production in human gingival fibroblasts challenged to tumor necrosis factor alpha in vitro.
Topics: Child; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flurbiprofen; Gingiva; Gingival Hyperplasia; Humans; Indomethacin; Interleukin-1; Phenytoin; Tumor Necrosis Factor-alpha; Up-Regulation | 1996 |
Involvement of prostaglandins in cachexia induced by T-cell leukemia in the rat.
Topics: Animals; Body Temperature Regulation; Body Weight; Cachexia; Feeding Behavior; Flurbiprofen; Indomethacin; Leukemia, T-Cell; Male; Organ Size; Oxygen; Prostaglandins; Rats | 1997 |
Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cyclic N-Oxides; Edetic Acid; Flurbiprofen; Free Radical Scavengers; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Isotope Labeling; Male; Metronidazole; Peritonitis; Permeability; Protein-Losing Enteropathies; Rats; Rats, Sprague-Dawley; Spin Labels; Stomach Ulcer | 1997 |
Reduction by antiinflammatory drugs of the response of corneal sensory nerve fibers to chemical irritation.
Topics: Acetic Acid; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Carbon Dioxide; Cats; Cornea; Cyclooxygenase Inhibitors; Diclofenac; Diltiazem; Electrophysiology; Female; Flurbiprofen; Indomethacin; Male; Nerve Fibers; Nociceptors; Pain; Trigeminal Nerve | 1997 |
Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Histamine Release; Ibuprofen; Immunoglobulin E; Indans; Indomethacin; Isoenzymes; Male; Mast Cells; Naphthaleneacetic Acids; Nitrobenzenes; Peritoneal Cavity; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Bacteria inhibit biosynthesis of bone matrix proteins in human osteoblasts.
Topics: Calcitriol; Cell Division; Collagen; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Insulin-Like Growth Factor I; Osteoblasts; Osteocalcin; Staphylococcus aureus; Staphylococcus epidermidis; Tumor Cells, Cultured | 1998 |
Bunazosin reduces intraocular pressure in rabbits by increasing uveoscleral outflow.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aqueous Humor; Cyclooxygenase Inhibitors; Fluorophotometry; Flurbiprofen; Indomethacin; Intraocular Pressure; Quinazolines; Rabbits; Sclera; Tonometry, Ocular; Uvea | 1998 |
Anti-inflammatory mechanism of alminoprofen: action on the phospholipid metabolism pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Flurbiprofen; Group II Phospholipases A2; Humans; Indans; Indomethacin; Isoenzymes; Melitten; Membrane Proteins; Phospholipases A; Phospholipases A2; Phospholipids; Propionates; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Rats; Rats, Wistar | 1999 |
Direct and indirect actions of fibroblast growth factor 2 on osteoclastic bone resorption in cultures.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Bone Marrow Cells; Bone Resorption; Calcium; Cells, Cultured; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dentin; Dose-Response Relationship, Drug; Enzyme Induction; Etodolac; Fibroblast Growth Factor 2; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Nitrobenzenes; Osteoblasts; Osteoclasts; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits; RNA, Messenger; Skull; Sulfonamides; Tartrate-Resistant Acid Phosphatase | 2000 |
Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.
Topics: Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Flurbiprofen; Heme; Indomethacin; Isoenzymes; Kinetics; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Protoporphyrins; Spectrometry, Mass, Electrospray Ionization | 2001 |
Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Computer Graphics; Computer Simulation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Energy Transfer; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Ketoprofen; Meclofenamic Acid; Mefenamic Acid; Membrane Proteins; Models, Molecular; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Naproxen; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley | 2002 |
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Lung; Membrane Proteins; Muscle, Smooth; NF-kappa B; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Response Elements; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 2003 |
Mechanisms of vasorelaxation to testosterone in the rat aorta.
Topics: Androgen Antagonists; Animals; Aorta, Thoracic; Calcium; Charybdotoxin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Flurbiprofen; Flutamide; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Wistar; Testosterone; Vasodilation | 2003 |
Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelin-1; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mesenteric Arteries; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred WKY; Receptors, Thromboxane A2, Prostaglandin H2; Sulfonamides; Thromboxane A2; Vascular Resistance; Vasoconstriction | 2004 |
The influence on human osteoblasts in vitro of non-steroidal anti-inflammatory drugs which act on different cyclooxygenase enzymes.
Topics: Acetaminophen; Alkaline Phosphatase; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Count; Cells, Cultured; Collagen; Cyclooxygenase Inhibitors; DNA; Flurbiprofen; Furans; Humans; Indomethacin; Nitrates; Nitric Oxide; Nitric Oxide Donors; Osteoblasts; Prostaglandin-Endoperoxide Synthases | 2004 |
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors | 2005 |
Characterization of the transdermal transport of flurbiprofen and indomethacin.
Topics: Administration, Cutaneous; Animals; Biological Transport; Cell Line; Flurbiprofen; Gene Expression Profiling; Humans; Indomethacin; Keratinocytes; Male; Membrane Transport Proteins; Mice; Mice, Hairless; Skin | 2006 |
Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Capillary Permeability; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Male; Perfusion; Protein Binding; Rats; Rats, Wistar; Serum Albumin, Bovine | 2006 |
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lactones; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Time Factors; Up-Regulation | 2006 |
Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Flurbiprofen; Humans; Hydrogen-Ion Concentration; Indomethacin; Ionic Liquids; Ketoprofen; Molecular Structure; Naproxen; Phenylbutyrates; Reproducibility of Results; Tolmetin | 2008 |
Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats.
Topics: Animals; Astrocytes; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Estrogens; Female; Flurbiprofen; Gonadotropin-Releasing Hormone; Indomethacin; Luteinizing Hormone; Membrane Proteins; Microglia; Neurons; Nitrobenzenes; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Wistar; Sulfonamides; Time Factors | 2009 |
Determination of non-steroidal anti-inflammatory drugs in urine by the combination of stir membrane liquid-liquid-liquid microextraction and liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Flurbiprofen; Humans; Indomethacin; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen | 2012 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin | 2012 |
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides | 2013 |
Cyclooxygenase metabolism mediates vasorelaxation to 2-arachidonoylglycerol (2-AG) in human mesenteric arteries.
Topics: Arachidonic Acids; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Endocannabinoids; Flurbiprofen; Glycerides; Humans; In Vitro Techniques; Indomethacin; Mesenteric Arteries; Vasodilation | 2014 |
COX Inhibition Increases
Topics: Allergens; Alternaria; Alternariosis; Animals; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cyclooxygenase Inhibitors; Eosinophils; Epithelial Cells; Female; Flurbiprofen; Humans; Immunity, Innate; Indomethacin; Interleukin-13; Interleukin-33; Interleukin-5; Lung; Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Knockout; Pneumonia | 2020 |
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction | 2022 |
Triphenyltin(IV) Carboxylates with Exceptionally High Cytotoxicity against Different Breast Cancer Cell Lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Carboxylic Acids; Cell Line, Tumor; Female; Flurbiprofen; Humans; Indomethacin; MCF-7 Cells; Tin | 2023 |