flurbiprofen and dinoprostone

flurbiprofen has been researched along with dinoprostone in 99 studies

Research

Studies (99)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (24.24)	18.7374
1990's	30 (30.30)	18.2507
2000's	33 (33.33)	29.6817
2010's	12 (12.12)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Duffy, EM; Jorgensen, WL	1
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N	1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bhattacherjee, P; Jaramillo, A; Paterson, CA; Sonnenfeld, G	1
Abramson, MM; Aeppli, DM; Friedman, HM; Hardie, ND; Offenbacher, S; Wolff, LF	1
Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Odle, BM; Offenbacher, S; Smith, MA; Williams, RC	1
Doerrler, W; Feingold, KR; Grünfeld, C; Hardardóttir, I	1
Coates, TD; Fasano, AP; McDonnell, PJ; Moreira, H; Sevanian, A; Silverman, DL	1
Furman, BL; Gray, GA; Parratt, JR	1
Boraschi, D; Dewhirst, FE; Lerner, UH; Ljunggren, O	1
Fernandes, G; Flescher, E; Fossum, D; Gray, PJ; Harper, MJ; Talal, N	1
Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC	1
Cyran, JA; Lea, MA; Lysz, TW	1
Lerner, UH; Ljunggren, O; Modéer, T	1
Douglas, JG; Dubyak, G; Welsh, C	1
Fall, PM; Raisz, LG; Simmons, HA	1
Bhuyan, DK; Bhuyan, KC; Camras, CB; Lee, KW; Podos, SM; Wang, RF	1
Aked, D; Foster, SJ; Howarth, A; McCormick, ME	1
Karmali, RA; Marsh, J	2
Fischer, SM; Fürstenberger, G; Marks, F; Slaga, TJ	1
Rosenbaum, JT; Rubin, RM	1
de Jong, PE; de Zeeuw, D; Donker, AJ; Pratt, JJ; van der Hem, GK; Vriesendorp, R	1
Bockman, RS; Kelley, DB; Weintraub, AS	1
Foy, JM; Nuhu, SZ	2
Kulkarni, PS; Srinivasan, BD	1
Karmali, R; Pelliccione, NJ; Pinto, J; Rivlin, RS	1
Rampton, DS; Sladen, GE	1
Hertting, G; Knepel, W; Vlaskovska, M	1
Lands, WE; MacAdams, MR; Pek, SB	1
Karmali, RA	1
Pek, SB; Walsh, MF	1
Buck, AC; Lote, CJ; Sampson, WF	1
Jawad, AM; Rogers, HJ	1
Rudland, PS; Tsao, SW; Twiston Davies, AC	1
Brown, CG; Poyser, NL	1
Barnes, PJ; Giembycz, MA; Meja, K; Seldon, PM	1
Gupta, A; Leal-Berumen, I; Marshall, JS; O'Byrne, P; Richards, CD	1
Buchanan, W; Doyle, MJ; Goodale, MB; Haigh, S; Jeffcoat, MK; Meredith, MP; Nelson, SL; Reddy, MS; Wehmeyer, KR	1
Armstrong, RA; Jones, RL; Marr, C	1
al-Zadjali, KH; Imler, MP; Ohia, SE	1
Bennett, J; Delamere, F; Holland, E; Knox, A; Patel, S; Pavord, I	1
Collins, JG; Edwards, G; Heasman, PA; Offenbacher, S; Seymour, RA	1
McGrath, JC; Smith, GC	1
Brunius, G; Modéer, T; Shinoda, K; Yucel-Lindberg, T	1
Brune, K; Geisslinger, G; Neupert, W; Oelkers, R	1
Del Soldato, P; di Giamberardino, M; Padovano, R; Panara, MR; Patrignani, P; Rotondo, MT; Santini, G; Sciulli, MG	1
Brune, K; Geisslinger, G; Neupert, W; Oelkers, R; Williams, KM	1
Hughes-Fulford, M; Tjandrawinata, RR	1
Boman, B; Hughes-Fulford, M	1
Hargreaves, KM; Roszkowski, MT; Swift, JQ	1
Chen, D; Pierce, WM; Waite, LC	1
Lerner, UH; Ohlin, A; Rosenquist, JB; Sundqvist, G	1
Kress, M; Reeh, PW; Sauer, SK; Schäfer, D	1
Diab, N; Domage, G; Dray, F; Mace, JL; Raguenes-Nicol, C; Russo-Marie, F; Solito, E; Streichenberger, G	1
Brune, K; Coste, O; Geisslinger, G; Muth-Selbach, U; Schaible, HG; Schrödter, A; Tegeder, I; Vetter, G	1
Chen, Y; Hughes-Fulford, M	1
Allegretti, M; Bertini, R; Biordi, L; Caselli, G; Martinotti, S; Marullo, A; Mascagni, P; Sabbatini, V	1
Carballosa Coré-Bodelier, VM; Van Delft, JL; van Haeringen, NJ; van Sorge, AA	1
Carballosa Coré-Bodelier, VM; van Haeringen, NJ; van Sorge, AA	1
Beck, KC; Morrow, JD; O'Malley, KA; Suman, OE	1
Brune, K; Hinz, B; Pahl, A	1
Averbeck, B; Reeh, PW	1
Brune, K; Euchenhofer, C; Geisslinger, G; Grösch, S; Gühring, H; Israr, E; Niederberger, E; Tegeder, I	1
Ajmone-Cat, MA; Minghetti, L; Nicolini, A	1
Nishinaka, T; Ohnishi, H; Oshikawa, M; Sato, K; Taenaka, Y; Takano, H; Takewa, Y; Tatsumi, E	1
Kato, S; Kunikata, T; Miyazawa, T; Takeuchi, K; Tanaka, A	1
Corbett, L; Knox, AJ; Nie, M; Pang, L	1
Ates, M; Gühring, H; Hamza, M; Seidel, K	1
Ates, M; Gühring, H; Hamza, M; Kotalla, CE; Ledent, C; Seidel, K	1
Chiu, HC; Fang, CL; Fang, JY; Hwang, TL	1
Averbeck, B; Reeh, WP; Zimmermann, K	1
Fortier, MA; Parent, J; Villeneuve, C	1
Averbeck, B; Izydorczyk, I; Peisler, M; Reeh, PW	1
Bolla, M; Habib, A; Henrion, D; Levy, BI; Levy-Toledano, S; Loufrani, L; You, D	1
Kulkarni, KH; LeDay, AM; Ohia, SE; Opere, CA	1
Breese, E; Del Soldato, P; Mitchell, J; Warner, T; Wood, E; Zacharowski, P	1
Bernardo, A; Gasparini, L; Minghetti, L; Ongini, E	1
Ajmone-Cat, MA; Ekdahl, CT; Iosif, RE; Kokaia, Z; Lindvall, O; Minghetti, L	1
Takahira, Y; Takeuchi, K; Tanaka, A; Yokota, A	1
Avondo, S; Cardile, V; Garufi, F; Gentile, B; Panico, AM; Ronsisvalle, S	1
Demirel, I; Kurtiş, B; Pinar, S; Serdar, M; Toyman, U; Tüter, G	1
Fukusaki, M; Inadomi, C; Sumikawa, K; Takada, M; Terao, Y; Yamashita, K	1
Basselin, M; Bell, JM; Lee, HJ; Rapoport, SI; Villacreses, NE	1
Destache, CJ; Ohia, SE; Opere, CA; Zhao, M	1
Hu, Y; Le Leu, RK; Martin, JE; Young, GP	1
Bjarnason, IT; Hotz-Behofsits, C; Simpson, RJ; Walley, M	1
De la Cruz, JP; Gonzalez-Correa, JA; Jebrouni, N; Lopez-Villodres, JA; Reyes, JJ; Ruiz-Moreno, MI	1
Dong, Y; Gan, L; Gan, Y; Jiang, M; Shen, J; Zhang, X; Zhu, C; Zhu, J	1
De La Cruz, JP; González-Correa, JA; Guerrero, A; López-Villodres, JA; Muñoz-Marin, J; Reyes, JJ	1
Endo, H; Futaki, N; Hirose, T; Hori, M; Ichihara, T; Kaku, S; Matsumoto, H; Mitani, A; Otsuka, N; Sekine, S; Sugimoto, M; Toda, Y	1
Angioni, C; Birod, K; Ebert, L; Geisslinger, G; Grösch, S; Hoffmann, M; Parnham, MJ; Steinhilber, D; Tegeder, I; Thomas, D; Wegner, MS; Wobst, I	1
Fukumoto, A; Hori, M; Kaku, S; Matsumoto, H; Tajima, K; Toda, Y	1
Chen, G; Li, K; Lu, J; Sun, X; Wang, S	1

Trials

7 trial(s) available for flurbiprofen and dinoprostone

Article	Year
Flurbiprofen effect on gingival crevicular fluid prostaglandin and thromboxane levels in humans. Journal of periodontal research, 1992, Volume: 27, Issue:5 Topics: Cross-Sectional Studies; Dinoprostone; Double-Blind Method; Female; Flurbiprofen; Gingival Crevicular Fluid; Humans; Longitudinal Studies; Male; Middle Aged; Periodontitis; Thromboxane B2	1992
A comparison of topical ketorolac, systemic flurbiprofen, and placebo for the inhibition of bone loss in adult periodontitis. Journal of periodontology, 1995, Volume: 66, Issue:5 Topics: Adult; Alveolar Bone Loss; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Dental Plaque Index; Dinoprostone; Double-Blind Method; Female; Flurbiprofen; Gingival Crevicular Fluid; Humans; Interleukin-1; Ketorolac Tromethamine; Male; Middle Aged; Mouthwashes; Periodontal Index; Periodontitis; Radiography; Statistics, Nonparametric; Subtraction Technique; Tolmetin; Treatment Outcome; Tromethamine	1995
Flurbiprofen in the prevention and treatment of experimental gingivitis. Journal of clinical periodontology, 1993, Volume: 20, Issue:10 Topics: Adult; Dinoprostone; Female; Flurbiprofen; Gingival Crevicular Fluid; Gingivitis; Humans; Leukotriene B4; Thromboxane B2	1993
Disposition and effects of flurbiprofen enantiomers in human serum and blister fluid. British journal of clinical pharmacology, 1997, Volume: 43, Issue:2 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Blister; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Male; Reference Values; Stereoisomerism; Thromboxane B2	1997
Effect of NSAID administration on tissue levels of immunoreactive prostaglandin E2, leukotriene B4, and (S)-flurbiprofen following extraction of impacted third molars. Pain, 1997, Volume: 73, Issue:3 Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Flurbiprofen; Humans; Immunohistochemistry; Leukotriene B4; Microdialysis; Molar, Third; Tooth Extraction; Tooth, Impacted; Wounds and Injuries	1997
Gingival crevicular fluid prostaglandin E(2) and thiobarbituric acid reactive substance levels in smokers and non-smokers with chronic periodontitis following phase I periodontal therapy and adjunctive use of flurbiprofen. Journal of periodontology, 2007, Volume: 78, Issue:1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Chronic Disease; Dental Scaling; Dinoprostone; Female; Flurbiprofen; Gingival Crevicular Fluid; Humans; Lipid Peroxidation; Male; Middle Aged; Periodontal Index; Periodontitis; Smoking; Statistics, Nonparametric; Thiobarbituric Acid Reactive Substances	2007
Preadministration of flurbiprofen suppresses prostaglandin production and postoperative pain in orthopedic patients undergoing tourniquet inflation. Journal of clinical anesthesia, 2007, Volume: 19, Issue:2 Topics: Analgesics; Analgesics, Opioid; Anterior Cruciate Ligament; Arthroplasty, Replacement, Knee; Buprenorphine; Dinoprostone; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Preanesthetic Medication; Preoperative Care; Prospective Studies; Time Factors; Tourniquets	2007

Other Studies

92 other study(ies) available for flurbiprofen and dinoprostone

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16 Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors	2003
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation. Current eye research, 1992, Volume: 11, Issue:6 Topics: Animals; Antigens; Arrestin; Autoantibodies; Dinoprostone; Disease Models, Animal; Eye Proteins; Female; Flurbiprofen; Immunoglobulin G; Indomethacin; Injections, Subcutaneous; Leukotriene B4; Membrane Proteins; Neutrophils; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Uveitis	1992
Effects of NSAIDs on beagle crevicular cyclooxygenase metabolites and periodontal bone loss. Journal of periodontal research, 1992, Volume: 27, Issue:3 Topics: Administration, Oral; Administration, Topical; Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Flurbiprofen; Gingival Crevicular Fluid; Ibuprofen; Naproxen; Prostaglandins F; Thromboxane B2	1992
Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism. Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1 Topics: 3T3 Cells; Adipose Tissue; Animals; Cells, Cultured; Cytokines; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Interferon Type I; Interferon-gamma; Interleukin-1; Kinetics; Lipolysis; Lipoprotein Lipase; Mice; Prostaglandins; Recombinant Proteins; Tumor Necrosis Factor-alpha	1992
Treatment of experimental Pseudomonas keratitis with cyclo-oxygenase and lipoxygenase inhibitors. Ophthalmology, 1991, Volume: 98, Issue:11 Topics: Administration, Topical; Animals; Corneal Ulcer; Dinoprostone; Disease Models, Animal; Eye Infections, Bacterial; Flurbiprofen; Leukotriene B4; Masoprocol; Pseudomonas Infections; Rabbits	1991
Endotoxin-induced impairment of vascular reactivity in the pithed rat: role of arachidonic acid metabolites. Circulatory shock, 1990, Volume: 31, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cyclooxygenase Inhibitors; Dinoprostone; Electric Stimulation; Endotoxins; Epoprostenol; Flurbiprofen; Hemodynamics; Iloprost; Male; Norepinephrine; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Spinal Cord; Sympathetic Nervous System	1990
Comparison of human interleukin-1 beta and its 163-171 peptide in bone resorption and the immune response. Cytokine, 1991, Volume: 3, Issue:2 Topics: Amino Acid Sequence; Animals; Antibody Formation; Bone and Bones; Bone Resorption; Bradykinin; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Interleukin-1; Interleukin-1beta; Kinetics; Mice; Mice, Inbred C3H; Molecular Sequence Data; Organ Culture Techniques; Peptide Fragments; Recombinant Proteins	1991
Aspirin-like drugs prime human T cells. Modulation of intracellular calcium concentrations. Journal of immunology (Baltimore, Md. : 1950), 1991, Apr-15, Volume: 146, Issue:8 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Arachidonic Acids; Calcium; CD8 Antigens; Cell Division; Chromatography, High Pressure Liquid; Diclofenac; Dinoprostone; Drug Synergism; Female; Flow Cytometry; Flurbiprofen; Humans; Indomethacin; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Radioimmunoassay; T-Lymphocytes	1991
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents. Agents and actions, 1990, Volume: 29, Issue:3-4 Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E	1990
Influence of inhibitors of eicosanoid metabolism on proliferation of rat hepatoma cells and on tumor-host interaction. Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 39, Issue:4 Topics: Acrylates; Animals; Arachidonic Acid; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Liver Neoplasms, Experimental; Male; Methacrylates; Rats; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured	1990
Bradykinin-2 receptor-mediated release of 3H-arachidonic acid and formation of prostaglandin E2 in human gingival fibroblasts. Journal of periodontal research, 1990, Volume: 25, Issue:6 Topics: Analysis of Variance; Arachidonic Acid; Arachidonic Acids; Bradykinin; Cells, Cultured; Child; Dinoprostone; Fibroblasts; Flurbiprofen; Gingiva; Humans; Indomethacin; Kallidin; Meclofenamic Acid; Receptors, Bradykinin; Receptors, Neurotransmitter	1990
Relationship between phospholipase C activation and prostaglandin E2 and cyclic adenosine monophosphate production in rabbit tubular epithelial cells. Effects of angiotensin, bradykinin, and arginine vasopressin. The Journal of clinical investigation, 1988, Volume: 81, Issue:3 Topics: Angiotensin II; Animals; Arginine Vasopressin; Bradykinin; Calcium; Cyclic AMP; Dinoprostone; Enzyme Activation; Epithelium; Flurbiprofen; Intracellular Fluid; Ion Channels; Kidney Tubules; Male; Neuropeptides; Pertussis Toxin; Phosphatidylinositols; Prostaglandins E; Rabbits; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella	1988
Biphasic effects of nonsteroidal anti-inflammatory drugs on prostaglandin production by cultured rat calvariae. Prostaglandins, 1989, Volume: 37, Issue:5 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Indomethacin; Piroxicam; Rats	1989
The role of prostaglandins in the para-aminoclonidine-induced reduction of intraocular pressure. Transactions of the American Ophthalmological Society, 1989, Volume: 87 Topics: Administration, Topical; Animals; Aqueous Humor; Clonidine; Dinoprost; Dinoprostone; Disease Models, Animal; Female; Flurbiprofen; Glaucoma; Intraocular Pressure; Laser Therapy; Macaca fascicularis; Pupil	1989
Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B1. Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10 Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Blood Proteins; Calcimycin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Skin	1986
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2. Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:1 Topics: Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunization; Indomethacin; Mammary Neoplasms, Experimental; Prostaglandins E; Rats; Rats, Inbred F344	1986
Events associated with mouse skin tumor promotion with respect to arachidonic acid metabolism: a comparison between SENCAR and NMRI mice. Cancer research, 1987, Jun-15, Volume: 47, Issue:12 Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; DNA Replication; Female; Flurbiprofen; Indomethacin; Mice; Ornithine Decarboxylase; Prostaglandins E; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate	1987
A platelet-activating factor antagonist inhibits interleukin 1-induced inflammation. Biochemical and biophysical research communications, 1988, Jul-15, Volume: 154, Issue:1 Topics: Animals; Aqueous Humor; Capillary Permeability; Dinoprostone; Eye; Female; Flurbiprofen; Inflammation; Interleukin-1; Leukocyte Count; Platelet Activating Factor; Prednisolone; Prostaglandins E; Proteins; Quinolinium Compounds; Rabbits; Recombinant Proteins	1988
Reduction of urinary protein and prostaglandin E2 excretion in the nephrotic syndrome by non-steroidal anti-inflammatory drugs. Clinical nephrology, 1986, Volume: 25, Issue:2 Topics: Adult; Anti-Inflammatory Agents; Diclofenac; Dinoprostone; Flurbiprofen; Glomerular Filtration Rate; Humans; Indomethacin; Male; Middle Aged; Nephrotic Syndrome; Prostaglandins E; Proteinuria; Renin; Sulindac	1986
Prostaglandin E2 induces receptive behaviors in female Xenopus laevis. Hormones and behavior, 1985, Volume: 19, Issue:4 Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Indomethacin; Ovariectomy; Posture; Prostaglandins E; Rana pipiens; Reaction Time; Sexual Behavior, Animal; Xenopus laevis	1985
Effect of three loop diuretics and prostaglandins E2 & I2 on the isolated perfused rat mesenteric vasculature. Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 273, Issue:2 Topics: Animals; Dinoprostone; Diuretics; Epoprostenol; Flurbiprofen; In Vitro Techniques; Male; Norepinephrine; Perfusion; Potassium Chloride; Prostaglandins E; Rats; Rats, Inbred Strains; Splanchnic Circulation; Vasoconstriction	1985
Comparative in vivo inhibitory effects of nonsteroidal anti-inflammatory agents on prostaglandin synthesis in rabbit ocular tissues. Archives of ophthalmology (Chicago, Ill. : 1960), 1985, Volume: 103, Issue:1 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Conjunctiva; Dinoprostone; Flurbiprofen; Indomethacin; Injections, Intraperitoneal; Prostaglandins E; Rabbits; Uvea	1985
Effects of riboflavin deficiency upon prostaglandin biosynthesis in rat kidney. Prostaglandins, leukotrienes, and medicine, 1985, Volume: 17, Issue:3 Topics: Animals; Dinoprost; Dinoprostone; Flurbiprofen; Kidney; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Rats; Riboflavin Deficiency	1985
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2. Prostaglandins, leukotrienes, and medicine, 1985, Volume: 20, Issue:3 Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunotherapy; Indomethacin; Mammary Neoplasms, Experimental; Propionates; Prostaglandins E; Rats; Rats, Inbred F344	1985
Relationship between rectal mucosal prostaglandin production and water and electrolyte transport in ulcerative colitis. Digestion, 1984, Volume: 30, Issue:1 Topics: Adrenal Cortex Hormones; Biological Transport; Body Water; Colitis, Ulcerative; Dinoprostone; Electrolytes; Flurbiprofen; Humans; Intestinal Absorption; Intestinal Mucosa; Potassium; Prostaglandins E; Rectum; Sodium; Sulfasalazine	1984
Adrenocorticotropin and beta-endorphin release from rat adenohypophysis in vitro: inhibition by prostaglandin E2 formed locally in response to vasopressin and corticotropin-releasing factor. Endocrinology, 1984, Volume: 115, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Endorphins; Flurbiprofen; Indomethacin; Male; Pituitary Gland, Anterior; Potassium; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains	1984
The effect of flurbiprofen, a potent inhibitor of prostaglandin synthesis, on insulin and glucagon release from isolated rat pancreas. Endocrinology, 1984, Volume: 114, Issue:4 Topics: Animals; Dinoprost; Dinoprostone; Flurbiprofen; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Propionates; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains	1984
Growth inhibition and prostaglandin metabolism in the R3230AC mammary adenocarcinoma by reduced glutathione. Cancer biochemistry biophysics, 1984, Volume: 7, Issue:2 Topics: Adenocarcinoma; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Glutathione; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microsomes; Prostaglandins; Prostaglandins E; Rats	1984
Possible role of endogenous arachidonic acid metabolites in stimulated release of insulin and glucagon from the isolated, perfused rat pancreas. Diabetes, 1984, Volume: 33, Issue:10 Topics: Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Arginine; Catechols; Dinoprostone; Flurbiprofen; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Masoprocol; Prostaglandins E; Rats; Rats, Inbred Strains	1984
The influence of renal prostaglandins on urinary calcium excretion in idiopathic urolithiasis. The Journal of urology, 1983, Volume: 129, Issue:2 Topics: Animals; Calcium; Dinoprostone; Flurbiprofen; Indomethacin; Kidney; Macaca fascicularis; Male; Potassium; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Urinary Calculi	1983
The effects of flurbiprofen and indomethacin on the mitogenic response of human peripheral mononuclear cells. Immunopharmacology, 1984, Volume: 7, Issue:1 Topics: Adult; Anti-Inflammatory Agents; Cell Count; Cell Survival; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Flurbiprofen; Humans; Indomethacin; Lymphocyte Activation; Male; Mitogens; Monocytes; Propionates; Prostaglandins E	1984
Effect of bumetanide, frusemide and prostaglandin E2 on the isolated perfused kidney of rat and rabbit. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Animals; Bumetanide; Dinoprostone; Diuretics; Electric Stimulation; Flurbiprofen; Furosemide; In Vitro Techniques; Kidney; Male; Norepinephrine; Prostaglandins E; Rabbits; Rats; Rats, Inbred Strains; Renal Circulation	1984
Rat mammary preadipocytes in culture produce a trophic agent for mammary epithelia-prostaglandin E2. Journal of cellular physiology, 1984, Volume: 120, Issue:3 Topics: Adipose Tissue; Animals; Cell Count; Cell Line; Cells, Cultured; Culture Media; Dinoprost; Dinoprostone; DNA Replication; Epithelial Cells; Female; Flurbiprofen; Indomethacin; Mammary Glands, Animal; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Time Factors	1984
Studies on the control of prostaglandin production by the hypothalamus in relation to LH release in the rat. The Journal of endocrinology, 1984, Volume: 103, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Castration; Circadian Rhythm; Dinoprost; Dinoprostone; Estradiol; Estrus; Female; Flurbiprofen; Hypothalamus; Luteinizing Hormone; Median Eminence; Norepinephrine; Pregnancy; Preoptic Area; Progesterone; Prostaglandins; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Rats, Inbred Strains; Thromboxane B2	1984
Suppression of lipopolysaccharide-induced tumor necrosis factor-alpha generation from human peripheral blood monocytes by inhibitors of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Molecular pharmacology, 1995, Volume: 48, Issue:4 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Albuterol; Amino Acid Sequence; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Dexamethasone; Dinoprostone; Drug Interactions; Flurbiprofen; Humans; Isoenzymes; Leukocytes, Mononuclear; Lipopolysaccharides; Molecular Sequence Data; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Stimulation, Chemical; Time Factors; Tumor Necrosis Factor-alpha	1995
Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells. Journal of immunology (Baltimore, Md. : 1950), 1995, May-01, Volume: 154, Issue:9 Topics: Alprostadil; Animals; Dexamethasone; Dinoprostone; Flurbiprofen; Histamine Release; In Vitro Techniques; Interleukin-6; Mast Cells; Peritoneal Cavity; Prostaglandin D2; Prostaglandins; Rats; Rats, Inbred BN; Tumor Necrosis Factor-alpha	1995
Characterization of the EP-receptor mediating dilatation and potentiation of inflammation in rabbit skin. Prostaglandins, 1995, Volume: 49, Issue:4 Topics: 16,16-Dimethylprostaglandin E2; Alprostadil; Animals; Biphenyl Compounds; Blood Flow Velocity; Bradykinin; Dermatitis; Dinoprostone; Drug Synergism; Flurbiprofen; Heptanoic Acids; Kinetics; Male; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandins F, Synthetic; Rabbits; Receptors, Prostaglandin E; Skin; Vasodilation	1995
Inhibitory effect of prostaglandins on dopamine release from the retina. General pharmacology, 1994, Volume: 25, Issue:2 Topics: Animals; Apomorphine; Cyclooxygenase Inhibitors; Dinoprostone; Dopamine; Electric Stimulation; Flurbiprofen; In Vitro Techniques; Male; Melatonin; Prostaglandin Antagonists; Prostaglandins; Rabbits; Receptors, Cell Surface; Receptors, Dopamine D2; Receptors, Melatonin; Receptors, Prostaglandin; Retina; Xanthenes; Xanthones	1994
Production of PGE2 by bovine cultured airway smooth muscle cells and its inhibition by cyclo-oxygenase inhibitors. British journal of pharmacology, 1994, Volume: 111, Issue:4 Topics: Animals; Aspirin; Bromodeoxyuridine; Cattle; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Muscle, Smooth; Trachea	1994
Characterisation of the effect of oxygen tension on response of fetal rabbit ductus arteriosus to vasodilators. Cardiovascular research, 1993, Volume: 27, Issue:12 Topics: Adenosine; Animals; Atrial Natriuretic Factor; Benzopyrans; Colforsin; Cromakalim; Culture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Ductus Arteriosus; Epoprostenol; Flurbiprofen; Indomethacin; Nifedipine; Nitroprusside; Norepinephrine; Oxygen; Pyrroles; Rabbits; Vasodilator Agents	1993
Effect of phenytoin on interleukin-1 beta production in human gingival fibroblasts challenged to tumor necrosis factor alpha in vitro. European journal of oral sciences, 1996, Volume: 104, Issue:1 Topics: Child; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fibroblasts; Flurbiprofen; Gingiva; Gingival Hyperplasia; Humans; Indomethacin; Interleukin-1; Phenytoin; Tumor Necrosis Factor-alpha; Up-Regulation	1996
A new reliable chemiluminescence immunoassay (CLIA) for prostaglandin E2 using enhanced luminol as substrate. Prostaglandins, 1996, Volume: 52, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blister; Dinoprostone; Evaluation Studies as Topic; Exudates and Transudates; Flurbiprofen; Humans; Immunoassay; Luminescent Measurements; Luminol; Mice; Sensitivity and Specificity; Suction; Ultraviolet Rays	1996
Effects of flurbiprofen and flurbinitroxybutylester on prostaglandin endoperoxide synthases. European journal of pharmacology, 1996, Nov-28, Volume: 316, Issue:1 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Dinoprostone; Drug Stability; Female; Flurbiprofen; Humans; Isoenzymes; Leukocytes, Mononuclear; Male; Middle Aged; Thromboxane B2	1996
Up-regulation of cyclooxygenase-2 by product-prostaglandin E2. Advances in experimental medicine and biology, 1997, Volume: 407 Topics: Anti-Inflammatory Agents, Non-Steroidal; Carcinoma; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dietary Fats; Dinoprostone; Enzyme Induction; Feedback; Flurbiprofen; Genes, Immediate-Early; Humans; Isoenzymes; Male; Membrane Proteins; Models, Biological; Neoplasm Proteins; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tumor Cells, Cultured	1997
Growth regulation of Gardner's syndrome colorectal cancer cells by NSAIDs. Advances in experimental medicine and biology, 1997, Volume: 407 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinoma; Cell Division; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA, Complementary; Flurbiprofen; Gardner Syndrome; Genes, p53; Humans; Isoenzymes; Membrane Proteins; Models, Biological; Neoplasm Proteins; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; RNA, Neoplasm	1997
In vitro bone resorption is dependent on physiological concentrations of zinc. Biological trace element research, 1998, Volume: 61, Issue:1 Topics: Acid Phosphatase; Animals; Bone Resorption; Calcium; Chelating Agents; Chick Embryo; Cyclooxygenase Inhibitors; Dinoprostone; DNA Replication; Flurbiprofen; Hydroxyurea; In Vitro Techniques; Isoenzymes; Nucleic Acid Synthesis Inhibitors; Parathyroid Hormone; Picolinic Acids; Tartrate-Resistant Acid Phosphatase; Tibia; Zinc	1998
Bacteria inhibit biosynthesis of bone matrix proteins in human osteoblasts. Clinical orthopaedics and related research, 1998, Issue:346 Topics: Calcitriol; Cell Division; Collagen; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Insulin-Like Growth Factor I; Osteoblasts; Osteocalcin; Staphylococcus aureus; Staphylococcus epidermidis; Tumor Cells, Cultured	1998
Stimulated prostaglandin E2 release from rat skin, in vitro. Life sciences, 1998, Volume: 62, Issue:22 Topics: Animals; Bradykinin; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Combinations; Flurbiprofen; Histamine; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Rats; Rats, Wistar; Serotonin; Skin	1998
Anti-inflammatory mechanism of alminoprofen: action on the phospholipid metabolism pathway. Biochemical pharmacology, 1999, Feb-15, Volume: 57, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Flurbiprofen; Group II Phospholipases A2; Humans; Indans; Indomethacin; Isoenzymes; Melitten; Membrane Proteins; Phospholipases A; Phospholipases A2; Phospholipids; Propionates; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Rats; Rats, Wistar	1999
Inhibition of noxious stimulus-induced spinal prostaglandin E2 release by flurbiprofen enantiomers: a microdialysis study. Journal of neurochemistry, 2000, Volume: 74, Issue:5 Topics: Animals; Behavior, Animal; Blood; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Formaldehyde; Injections, Subcutaneous; Isoenzymes; Male; Membrane Proteins; Microdialysis; Motor Activity; Nociceptors; Osmolar Concentration; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Spinal Cord; Stereoisomerism; Stimulation, Chemical	2000
Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells. British journal of cancer, 2000, Volume: 82, Issue:12 Topics: Arachidonic Acid; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Flurbiprofen; Gene Expression; Genes, fos; Humans; Isoquinolines; Male; Prostatic Neoplasms; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Signal Transduction; Sulfonamides; Tumor Cells, Cultured	2000
R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production. European cytokine network, 2000, Volume: 11, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Female; Flurbiprofen; Ibuprofen; In Vitro Techniques; Interleukin-10; Interleukin-6; Ketoprofen; Lipopolysaccharides; Macrophages, Peritoneal; Mice; RNA, Messenger; Stereoisomerism; Tumor Necrosis Factor-alpha	2000
Flurbiprofen and enantiomers in ophthalmic solution tested as inhibitors of prostanoid synthesis in human blood. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Escherichia coli; Flurbiprofen; Humans; Isoenzymes; Lipopolysaccharides; Meloxicam; Membrane Proteins; Monocytes; Ophthalmic Solutions; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thiazines; Thiazoles; Thromboxane B2	2000
Constitutive cyclooxygenase-1 and induced cyclooxygenase-2 in isolated human iris inhibited by S(+) flurbiprofen. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2000, Volume: 16, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Escherichia coli; Flurbiprofen; Humans; Iris; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Stereoisomerism	2000
Airway function after cyclooxygenase inhibition during hyperpnea-induced bronchoconstriction in guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:5 Topics: Airway Resistance; Animals; Arachidonic Acid; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Guinea Pigs; Hyperventilation; Lung; Lung Volume Measurements; Male; Prostaglandin-Endoperoxide Synthases	2000
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. Biochemical and biophysical research communications, 2000, Nov-30, Volume: 278, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Bucladesine; Cells, Cultured; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Transcription, Genetic	2000
Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin. Neuropharmacology, 2001, Volume: 40, Issue:3 Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Dinoprostone; Drug Combinations; Female; Flurbiprofen; Histamine; Hydrogen-Ion Concentration; In Vitro Techniques; Inflammation Mediators; Male; Nociceptors; Rats; Rats, Wistar; Serotonin; Skin; Substance P	2001
Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:3 Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; I-kappa B Proteins; Inflammation; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Stereoisomerism; Transcription Factor AP-1; Zymosan	2001
Differential effects of the nonsteroidal antiinflammatory drug flurbiprofen and its nitric oxide-releasing derivative, nitroflurbiprofen, on prostaglandin E(2), interleukin-1beta, and nitric oxide synthesis by activated microglia. Journal of neuroscience research, 2001, Nov-15, Volume: 66, Issue:4 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Survival; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Encephalitis; Flurbiprofen; Interleukin-1; Lipopolysaccharides; Macrophages; Microglia; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroso Compounds; Prostaglandin-Endoperoxide Synthases; Rats	2001
Prostaglandin synthesis inhibitor affects humoral conditions and oxygen metabolism during normothermic cardiopulmonary bypass. Artificial organs, 2002, Volume: 26, Issue:8 Topics: Analysis of Variance; Animals; Cardiopulmonary Bypass; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Goats; Hemodynamics; Hypotension; Norepinephrine; Oxygen; Oxygen Consumption; Vasoconstrictor Agents	2002
Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats. Digestion, 2002, Volume: 66, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Naproxen; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Sprague-Dawley	2002
Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. Journal of immunology (Baltimore, Md. : 1950), 2003, Jan-15, Volume: 170, Issue:2 Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Flurbiprofen; Humans; Indomethacin; Isoenzymes; Lung; Membrane Proteins; Muscle, Smooth; NF-kappa B; Nitrobenzenes; Promoter Regions, Genetic; Prostaglandin Antagonists; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Response Elements; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation	2003
Flurbiprofen inhibits capsaicin induced calcitonin gene related peptide release from rat spinal cord via an endocannabinoid dependent mechanism. Neuroscience letters, 2003, Feb-27, Volume: 338, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Capsaicin; Cyclooxygenase Inhibitors; Dinoprostone; Dronabinol; Endocannabinoids; Fatty Acids, Unsaturated; Flurbiprofen; Immunoassay; In Vitro Techniques; Phospholipases A; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Spinal Cord	2003
Intrathecally applied flurbiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test. The European journal of neuroscience, 2003, Volume: 17, Issue:3 Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Modulators; Cyclooxygenase Inhibitors; Dinoprostone; Endocannabinoids; Enzyme Inhibitors; Flurbiprofen; Formaldehyde; In Vitro Techniques; Injections, Spinal; Male; Mice; Muscle Contraction; Muscle, Smooth; Pain Measurement; Phospholipases A; Phospholipases A2; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Vas Deferens	2003
In vitro and in vivo evaluations of the efficacy and safety of skin permeation enhancers using flurbiprofen as a model drug. International journal of pharmaceutics, 2003, Apr-14, Volume: 255, Issue:1-2 Topics: Adjuvants, Pharmaceutic; Administration, Cutaneous; Animals; Azepines; Cells, Cultured; Chromatography, High Pressure Liquid; Colorimetry; Cyclohexenes; Dinoprostone; Erythema; Fatty Acids; Female; Fibroblasts; Flurbiprofen; Humans; Hydrogels; Limonene; Microscopy; Phosphatidylcholines; Rats; Rats, Wistar; Skin; Skin Absorption; Terpenes	2003
S+ -flurbiprofen but not 5-HT1 agonists suppress basal and stimulated CGRP and PGE2 release from isolated rat dura mater. Pain, 2003, Volume: 103, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Culture Media, Conditioned; Dinoprostone; Drug Interactions; Dura Mater; Flurbiprofen; Immunoassay; In Vitro Techniques; Indoles; Inflammation Mediators; Male; Piperidines; Pyridines; Pyrroles; Rats; Rats, Wistar; Serotonin Receptor Agonists; Time Factors; Tryptamines	2003
Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium. Reproduction (Cambridge, England), 2003, Volume: 126, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blotting, Western; Cattle; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Endometrium; Epithelial Cells; Female; Flurbiprofen; Isoenzymes; Nitrobenzenes; Oxytocin; Prostaglandin-Endoperoxide Synthases; Salicylates; Stimulation, Chemical; Sulfonamides	2003
Inflammatory mediators do not stimulate CGRP release if prostaglandin synthesis is blocked by S(+)-flurbiprofen in isolated rat skin. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2003, Volume: 52, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Calcitonin Gene-Related Peptide; Dinoprostone; Flurbiprofen; Histamine; In Vitro Techniques; Inflammation Mediators; Male; Potassium Chloride; Rats; Rats, Wistar; Serotonin; Skin	2003
Cyclooxygenase involvement in thromboxane-dependent contraction in rat mesenteric resistance arteries. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Endothelin-1; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mesenteric Arteries; Organic Chemicals; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred WKY; Receptors, Thromboxane A2, Prostaglandin H2; Sulfonamides; Thromboxane A2; Vascular Resistance; Vasoconstriction	2004
Arachidonic acid metabolites and peroxide-induced inhibition of [3H]D-aspartate release from bovine isolated retinae. Current eye research, 2004, Volume: 28, Issue:5 Topics: Animals; Arachidonic Acids; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; D-Aspartic Acid; Dinoprost; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Unsaturated; Flurbiprofen; Hydrazines; Hydrogen Peroxide; Potassium Chloride; Receptors, Thromboxane; Retina	2004
NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives. European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3 Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blotting, Western; Cells, Cultured; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Indomethacin; Membrane Proteins; Naproxen; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Prostaglandin-Endoperoxide Synthases; Purinones; Synovial Membrane; Time Factors	2005
Dynamic regulation of microglial functions by the non-steroidal anti-inflammatory drug NCX 2216: implications for chronic treatments of neurodegenerative diseases. Neurobiology of disease, 2006, Volume: 22, Issue:1 Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinoprostone; Encephalitis; Flurbiprofen; Gliosis; Interleukin-1; Microglia; Neurodegenerative Diseases; Nitrates; Nitric Oxide; PPAR gamma; Rats; Transcriptional Activation; Tumor Necrosis Factor-alpha	2006
Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: no impact on survival of seizure-generated neurons. Neurobiology of disease, 2006, Volume: 23, Issue:1 Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Proliferation; Cell Survival; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Hippocampus; Immunohistochemistry; Male; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Stem Cells	2006
Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs. Digestive diseases and sciences, 2006, Volume: 51, Issue:7 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Disease Models, Animal; Enterobacteriaceae; Flurbiprofen; Gastrointestinal Motility; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Lactones; Male; Naproxen; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfones; Time Factors; Up-Regulation	2006
"In vitro" differences among (R) and (S) enantiomers of profens in their activities related to articular pathophysiology. Inflammation, 2005, Volume: 29, Issue:4-6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; Dinoprostone; Femur Head; Flurbiprofen; Glycosaminoglycans; Humans; Interleukin-1beta; Ketoprofen; Matrix Metalloproteinase 3; Nitrites; Reactive Oxygen Species; Stereoisomerism	2005
Flurbiprofen, a cyclooxygenase inhibitor, reduces the brain arachidonic acid signal in response to the cholinergic muscarinic agonist, arecoline, in awake rats. Neurochemical research, 2007, Volume: 32, Issue:11 Topics: Animals; Arachidonic Acid; Arecoline; Brain; Dinoprostone; Fatty Acids, Nonesterified; Flurbiprofen; Male; Phospholipases A2; Rats; Rats, Inbred F344; Signal Transduction; Thromboxane B2; Wakefulness	2007
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo. Neurochemical research, 2009, Volume: 34, Issue:12 Topics: Animals; Benzofurans; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cyclooxygenase Inhibitors; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Fatty Acids, Unsaturated; Flurbiprofen; Glutamic Acid; Glutamine; Glycine; Hydrazines; Isoprostanes; Neurotransmitter Agents; Nitrobenzenes; Prostaglandins; Receptors, Prostaglandin; Retina; Sulfonamides; Xanthones	2009
R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production. American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:6 Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Eicosanoids; Flurbiprofen; Male; Mucins; Rats; Rats, Sprague-Dawley; Sulindac	2010
Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents. Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:7-8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Dinoprostone; Flurbiprofen; Inflammation; Intestine, Small; Male; Mice; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides	2010
Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. Anesthesia and analgesia, 2010, Volume: 111, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Humans; Ibuprofen; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2	2010
Novel NSAIDs ophthalmic formulation: flurbiprofen axetil emulsion with low irritancy and improved anti-inflammation effect. International journal of pharmaceutics, 2011, Jun-30, Volume: 412, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Biological Availability; Cell Count; Cornea; Dinoprostone; Drug Compounding; Drug Stability; Emulsifying Agents; Emulsions; Flurbiprofen; Leukocytes; Male; Nanospheres; Ophthalmic Solutions; Particle Size; Pharmaceutical Vehicles; Prodrugs; Rabbits; Temperature; Uveitis	2011
Lack of enantiomeric influence on the brain cytoprotective effect of ibuprofen and flurbiprofen. Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:2 Topics: Animals; Brain; Cyclooxygenase Inhibitors; Cytokines; Cytoprotection; Dinoprostone; Flurbiprofen; Hypoxia, Brain; Ibuprofen; In Vitro Techniques; Lipid Peroxidation; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stereoisomerism; Tyrosine	2011
Analgesic Effect of the Newly Developed S(+)-Flurbiprofen Plaster on Inflammatory Pain in a Rat Adjuvant-Induced Arthritis Model. Drug development research, 2016, Volume: 77, Issue:1 Topics: Administration, Topical; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Flurbiprofen; Humans; Male; Pain Threshold; Rats; Rats, Sprague-Dawley	2016
R-Flurbiprofen Traps Prostaglandins within Cells by Inhibition of Multidrug Resistance-Associated Protein-4. International journal of molecular sciences, 2016, Dec-30, Volume: 18, Issue:1 Topics: A549 Cells; Arachidonic Acid; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cyclooxygenase Inhibitors; Dinoprostone; Flurbiprofen; Gene Expression; Group IV Phospholipases A2; HeLa Cells; Humans; Interleukin-1beta; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stereoisomerism; Tumor Necrosis Factor-alpha	2016
Analgesic effect of S (+)-flurbiprofen plaster in a rat model of knee arthritis: analysis of gait and synovial fluid prostaglandin E The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:7 Topics: Analgesics; Animals; Arthritis, Experimental; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Flurbiprofen; Gait; Ketoprofen; Male; Phenylpropionates; Rats; Synovial Fluid; Transdermal Patch	2018
THE INVESTIGATION OF EFFECT OF FLURBIPROFEN AXETIL ON THE TISSUE GROWTH AND THE CONTENT OF PGE2 IN CERVICAL CANCER. Acta poloniae pharmaceutica, 2016, Volume: 73, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Flurbiprofen; HeLa Cells; Humans; Mice; Mice, Nude; Uterine Cervical Neoplasms	2016