flurbiprofen has been researched along with amyloid beta-peptides in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beech, W; Chu, T; Cole, GM; Morihara, T; Ubeda, O | 1 |
| Cenacchi, V; Del Giudice, E; Facchinetti, F; Grassi, F; Imbimbo, BP; Leon, A; Moretto, N; Ottonello, S; Puccini, P; Riccardi, B; Villetti, G; Volta, R | 1 |
| Baroc, MF; Colavito, D; D'Arrigo, A; Dalle Carbonare, M; De Strooper, B; Del Giudice, E; Facchinetti, F; Imbimbo, BP; Leon, A; Pietrini, V; Serneels, L; Villetti, G; Volta, R | 1 |
| Cenacchi, V; Facchinetti, F; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Villetti, G; Volta, R; Windisch, M | 1 |
| Cao, X; Chen, J; Chen, Y; Huang, X; Liu, Y; Xu, H; Xu, R; You, X; Zhang, X; Zhang, YW | 1 |
| Baldassarro, VA; Baroc, MF; Calzà, L; Fernandez, M; Ferraro, L; Giardino, L; Giuliani, A; Gusciglio, M; Imbimbo, BP; Lorenzini, L; Mangano, C; Ottonello, S; Pietrini, V; Sivilia, S; Villetti, G; Viscomi, AR | 1 |
| Chen, Y; Lehmann, J; Liao, H; Peng, S; Sun, J; Zhang, Y | 1 |
7 other study(ies) available for flurbiprofen and amyloid beta-peptides
| Article | Year |
|---|---|
Selective inhibition of Abeta42 production by NSAID R-enantiomers.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Ibuprofen; Kidney; Mutation; NF-kappa B; Peptide Fragments; Peptides; Stereoisomerism; Transfection | 2002 |
In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents.
Topics: Administration, Oral; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Line, Tumor; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cyclopropanes; Dose-Response Relationship, Drug; Down-Regulation; Flurbiprofen; Gene Expression; Humans; Insecta; Membrane Proteins; Mice; Mice, Transgenic; Mutation; Nootropic Agents; Peptide Fragments; Time Factors; Transfection | 2007 |
1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Line; Cyclopropanes; Disease Models, Animal; Female; Flurbiprofen; Humans; Male; Mice; Mice, Transgenic; Molecular Structure; Peptide Fragments; Tissue Distribution | 2007 |
CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain; Cyclopropanes; Flurbiprofen; Humans; Ibuprofen; Learning Disabilities; Memory; Mice; Mice, Transgenic; Microglia; Mutation; Peptide Fragments; Plaque, Amyloid | 2009 |
Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Biotinylation; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flurbiprofen; Gene Expression Regulation; Humans; Immunoprecipitation; Mice; Oligopeptides; Peptide Fragments; Protein Binding; Receptors, Notch; Retinoid X Receptors; RNA, Small Interfering; Transfection | 2009 |
Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antipsychotic Agents; Brain; Cyclin A; Cyclopropanes; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Flurbiprofen; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mutation; Peptide Fragments; Phosphopyruvate Hydratase; Plaque, Amyloid; Recognition, Psychology; Silver Staining | 2013 |
Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Catalytic Domain; Cells, Cultured; Cholinesterase Inhibitors; Female; Flurbiprofen; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Peptide Fragments; Protein Conformation; Rats; Rats, Wistar; Structure-Activity Relationship; Tacrine | 2013 |