flurazepam has been researched along with gamma-aminobutyric acid in 85 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (63.53) | 18.7374 |
| 1990's | 20 (23.53) | 18.2507 |
| 2000's | 9 (10.59) | 29.6817 |
| 2010's | 2 (2.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM | 1 |
| Dray, A; Straughan, DW | 1 |
| Waddington, JL | 2 |
| Constanti, A; Nistri, A | 1 |
| Nestoros, JN; Nistri, A | 2 |
| Boakes, RJ; Martin, IL; Mitchell, PR | 1 |
| Franco, S; Schlosser, W | 1 |
| Geller, HM | 1 |
| Brand, SJ; Curtis, DR; Johnston, GA; Lodge, D | 1 |
| Tietz, EI; Xie, XH | 1 |
| Ramsey, VA; Rosenberg, HC; Tietz, EI | 1 |
| Browne, SE; Pertwee, RG; Ross, TM; Stretton, CD | 1 |
| Farb, DH; Friedman, L; Gibbs, TT; Roca, DJ; Rozenberg, I; Schiller, GD | 1 |
| Biello, SM; Harrington, ME; Mason, R | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| White, G | 1 |
| Friedman, DL; Redburn, DA | 1 |
| Chiu, TH; Ngur, DO; Rosenberg, HC | 1 |
| Chiu, TH; Rosenberg, HC; Tietz, EI | 1 |
| Gallager, DW; Wilson, MA | 1 |
| Haji, A; Takeda, R | 1 |
| Holden-Dye, L; Krogsgaard-Larsen, P; Nielsen, L; Walker, RJ | 1 |
| Rosenberg, HC; Tietz, EI; Zhang, H | 1 |
| Xu, NS; Yu, BJ; Zhang, JR | 1 |
| Rosenberg, HC; Tietz, EI | 1 |
| Gale, RG; Little, HJ; Nutt, DJ; Standing, BL; Taylor, SC | 1 |
| Greentree, SG; Pertwee, RG; Swift, PA | 1 |
| Vellucci, SV; Webster, RA | 1 |
| Namima, M; Sakai, Y | 1 |
| Jin, DS; Ren, YF; Zhou, TC | 1 |
| Agardh, E; Herrmann, R; Puro, DG; Yeh, HH | 1 |
| Hicks, TP; Jang, EK | 1 |
| Hicks, TP; Jang, EK; Oka, JI | 1 |
| Gray, JA; Green, AR | 1 |
| Lindgren, S; Simmonds, MA | 1 |
| Chapman, AG | 1 |
| Chiu, TH; Rosenberg, HC; Yu, O | 1 |
| Morrow, AL; Paul, SM | 1 |
| Azizi, SA; Chapin, JK; Cheng, JT; Sessler, FM; Waterhouse, BD | 1 |
| Boudinot, E; Champagnat, J; Denavit-Saubié, M; Foutz, AS; Gonsalves, SF; Morin-Surun, MP | 1 |
| Caspary, DM; Faingold, CL; Gehlbach, G | 1 |
| Little, HJ | 1 |
| Bokisch, AJ; Bold, JM; Gardner, CR; Perkins, MN; Roberts, CJ; Stone, TW; Walker, RJ | 1 |
| Corradetti, R; Moroni, F; Pepeu, G | 1 |
| Phillis, JW; Wu, PH | 1 |
| Fumagalli, R; Iuliano, E; Ongini, E; Racagni, G | 1 |
| Lorens, SA; Sainati, SM | 1 |
| Avoli, M; Brancati, A; Frank, C; Tancredi, V; White, P | 1 |
| Starr, MS | 1 |
| Simmonds, MA | 1 |
| Constanti, A; Krnjević, K; Nistri, A | 1 |
| Choi, DW; Farb, DH; Fischbach, GD | 1 |
| Bichard, AR; Little, HJ | 1 |
| Geller, HM; Moises, HC; Waterhouse, BD; Woodward, DJ; Yeh, HH | 1 |
| Starr, MS; Summerhayes, M | 1 |
| Geller, HM; Haas, H; Krespan, B; Springfield, SA | 1 |
| Berti, C; Nistri, A | 1 |
| Coward, DM | 1 |
| Kilpatrick, IC; Starr, MS; Summerhayes, M | 1 |
| Barker, JL; MacDonald, JF | 1 |
| Harris, DP; Lo, GF; Sinclair, JG | 1 |
| Jiang, Z | 1 |
| Tietz, EI; Xie, XH; Zeng, X | 1 |
| Chiu, TH; Li, M; Rosenberg, HC | 2 |
| Hu, XJ; Ticku, MK | 1 |
| Rosenberg, HC; Weng, X; Zhang, H | 1 |
| Smart, TG; Xie, X | 1 |
| Fukuda, H; Hicks, TP; Kobayashi, T; Nagao, T; Oka, JI | 1 |
| Gillespie, LL; Paterno, GD; Prasad, A; Reynolds, JN | 1 |
| Tietz, EI; Zeng, XJ | 1 |
| Delaney, AJ; Sah, P | 1 |
| Hamann, M; Richter, A | 1 |
| Popova, E | 1 |
| Cherubini, E; Marchionni, I; Petrini, EM; Sieghart, W; Zacchi, P | 1 |
| Barberis, A; Cherubini, E; Petrini, EM | 1 |
| Cherubini, E; Conti, F; Fattorini, G; Safiulina, VF | 1 |
| Mercik, K; Mozrzymas, JW; Piast, M | 1 |
| Lebida, K; Mercik, K; Mozrzymas, JW; Piast, M; Wójtowicz, T; Wyrembek, P | 1 |
| Lebida, K; Mozrzymas, JW; Piast, M; Wójtowicz, T; Wyrembek, P | 1 |
| Lebida, K; Mozrzymas, JW; Wójtowicz, T | 1 |
| Czajkowski, C; Hanson, SM | 1 |
| Brodzki, M; Czyzewska, MM; Jatczak, M; Kisiel, M; Mozrzymas, JW; Rutkowski, R | 1 |
2 review(s) available for flurazepam and gamma-aminobutyric acid
| Article | Year |
|---|---|
The role of receptor binding in drug discovery.
Topics: Animals; Drug Design; Humans; Receptors, Drug | 1993 |
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; Flurazepam; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Light; Morphine; Muscimol; Myoclonus; Serotonin; Urea; Valproic Acid | 1986 |
83 other study(ies) available for flurazepam and gamma-aminobutyric acid
| Article | Year |
|---|---|
Benzodiazepines: GABA and glycine receptors on single neurons in the rat medulla.
Topics: Aminobutyrates; Animals; Benzodiazepines; Bicuculline; Chlordiazepoxide; Evoked Potentials; Flurazepam; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Medulla Oblongata; Neurons; Neurotransmitter Agents; Nitrazepam; Rats; Receptors, Drug; Strychnine | 1976 |
GABA-like properties of flurazepam and baclofen suggested by rotational behaviour following unilateral intranigral injection: a comparison with the GABA agonist muscimol [proceedings].
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Baclofen; Behavior; Flurazepam; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Rats; Stereotyped Behavior; Substantia Nigra | 1977 |
Effects of flurazepam on amino acid-evoked responses recorded from the lobster muscle and the frog spinal cord.
Topics: Amino Acids; Animals; Anti-Anxiety Agents; Anura; Evoked Potentials; Flurazepam; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Muscles; Nephropidae; Neural Conduction; Spinal Cord; Spinal Nerve Roots | 1978 |
A presynaptic component of the action of iontophoretically applied flurazepam on feline cortical neurones.
Topics: Action Potentials; Animals; Anti-Anxiety Agents; Cats; Cerebral Cortex; Electroencephalography; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Iontophoresis; Neurons; Semicarbazides; Synapses | 1978 |
Behavioural evidence for GABAergic activity of the benzodiazepine flurazepam.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Behavior, Animal; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rotation; Substantia Nigra; Synaptic Transmission; Time Factors | 1978 |
Effects of microiontophoretically applied flurazepam on responses of cerebral cortical neurones to putative neurotransmitters.
Topics: Acetylcholine; Amino Acids; Animals; Cerebral Cortex; Dopamine; Female; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Male; Neural Inhibition; Neurons; Neurotransmitter Agents; Rats; Serotonin; Synaptic Transmission | 1979 |
Burst firing of cerebellar Purkinje neurones induced by benzodiazepines.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Male; Nitrazepam; Purkinje Cells; Rats; Synaptic Transmission | 1977 |
Modification of GABA-mediated depolarization of the cat ganglion by pentobarbital and two benzodiazepines.
Topics: Animals; Benzodiazepines; Bicuculline; Cats; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Pentobarbital; Picrotoxin | 1979 |
Water soluble benzodiazepines with agonistic and antagonistic actions on GABA-induced inhibition in cultured hypothalamus.
Topics: Animals; Animals, Newborn; Benzodiazepinones; Culture Techniques; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; Hypothalamus; Rats | 1979 |
Central actions of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellar Cortex; Diazepam; Flurazepam; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Rats; Spinal Cord | 1976 |
Reduction in potency of selective gamma-aminobutyric acidA agonists and diazepam in CA1 region of in vitro hippocampal slices from chronic flurazepam-treated rats.
Topics: Animals; Diazepam; Evoked Potentials; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Isonicotinic Acids; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Chronic flurazepam differentially regulates a behavioral effect of GABA agonists.
Topics: Animals; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; Isoxazoles; Male; Microinjections; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Rotation; Substantia Nigra; Time Factors | 1991 |
An investigation of the involvement of GABA in certain pharmacological effects of delta-9-tetrahydrocannabinol.
Topics: Amino Acids; Amino Acids, Neutral; Analgesics; Animals; Anticonvulsants; Body Temperature; Cannabidiol; Dronabinol; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nipecotic Acids; Pentylenetetrazole; Seizures; Tiagabine | 1991 |
gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Allosteric Regulation; Animals; Barbital; Barbiturates; Brain; Caffeine; Cells, Cultured; Chick Embryo; Flumazenil; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Kinetics; Neurons; Pentobarbital; Receptors, GABA-A; Tetrodotoxin; Theophylline; Veratridine | 1990 |
The effects of GABA and benzodiazepines on neurones in the suprachiasmatic nucleus (SCN) of Syrian hamsters.
Topics: Animals; Chlordiazepoxide; Circadian Rhythm; Cricetinae; Evoked Potentials; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesocricetus; Neurons; Suprachiasmatic Nucleus | 1991 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1990 |
GABAA-receptor-activated current in dorsal root ganglion neurons freshly isolated from adult rats.
Topics: Animals; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Male; Membrane Potentials; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina | 1990 |
Modulation of GABA-stimulated Cl- flux by a benzodiazepine agonist and an 'inverse agonist' after chronic flurazepam treatment.
Topics: Animals; Benzodiazepines; Bicuculline; Brain Chemistry; Carbolines; Chlorides; Dose-Response Relationship, Drug; Flurazepam; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains | 1990 |
Regional GABA/benzodiazepine receptor/chloride channel coupling after acute and chronic benzodiazepine treatment.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Bicuculline; Brain; Chlorides; Diazepam; Flunitrazepam; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical | 1989 |
Responses of substantia nigra pars reticulata neurons to benzodiazepine ligands after acute and prolonged diazepam exposure. I. Modulation of gamma-aminobutyric acid sensitivity.
Topics: Animals; Carbolines; Diazepam; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ligands; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1989 |
Microiontophoresis of flurazepam on inspiratory and postinspiratory neurons in the ventrolateral medulla of cats: an intracellular study in vivo.
Topics: Animals; Bicuculline; Cats; Electrophysiology; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Medulla Oblongata; Membrane Potentials; Microelectrodes; Neurons; Respiration; Synaptic Transmission | 1989 |
GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site.
Topics: Animals; Ascaris; Baclofen; Binding, Competitive; Dieldrin; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Pentobarbital; Receptors, GABA-A; Stereoisomerism | 1989 |
Injection of benzodiazepines but not GABA or muscimol into pars reticulata substantia nigra suppresses pentylenetetrazol seizures.
Topics: Animals; Benzodiazepines; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1989 |
[Effects of microiontophoretically applied flurazepam on the respiratory units in the region of the nucleus parabrachialis of the rabbit].
Topics: Animals; Electrophysiology; Female; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Male; Pons; Rabbits; Respiration | 1989 |
Behavioral measurement of benzodiazepine tolerance and GABAergic subsensitivity in the substantia nigra pars reticulata.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Receptors, GABA-A; Stereotyped Behavior; Substantia Nigra; Time Factors | 1988 |
Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice.
Topics: Animals; Anticonvulsants; Bicuculline; Body Temperature; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; Infusions, Intravenous; Male; Mice; Motor Activity; Pentobarbital; Picrotoxin; Receptors, GABA-A; Seizures; Time Factors | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
GABA and benzodiazepine-induced modification of [14C]L-glutamic acid release from rat spinal cord slices.
Topics: Aminooxyacetic Acid; Animals; Bicuculline; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Potassium; Rats; Spinal Cord | 1985 |
Inhibitory effect on 3H-diazepam binding and potentiating action on GABA of ethyl loflazepate, a new minor tranquilizer.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Guinea Pigs; Male; Purkinje Cells | 1985 |
[Effects of syntropan, atropine and scopolamine on the uptake of GABA by homogenates of the rat cerebrum].
Topics: Animals; Atropine; Brain; Flurazepam; gamma-Aminobutyric Acid; Male; Parasympatholytics; Phenylacetates; Rats; Scopolamine | 1986 |
gamma-Aminobutyric acid-mediated inhibition at cholinergic synapses formed by cultured retinal neurons.
Topics: Animals; Bicuculline; Cells, Cultured; Chick Embryo; Cholinergic Fibers; Flurazepam; gamma-Aminobutyric Acid; Neural Inhibition; Neurons; Retina; Synaptic Transmission | 1985 |
The gamma-aminobutyric acid-mimetic action of omega-aminocaprylic acid in rat cortex.
Topics: Animals; Bicuculline; Caprylates; Cerebral Cortex; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; Models, Chemical; Rats; Receptors, GABA-A | 1985 |
Benzodiazepine receptor involvement in the control of receptive field size and responsiveness in primary somatosensory cortex.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Cats; Diazepam; Female; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Neurons; Receptors, GABA-A; Sensory Thresholds; Somatosensory Cortex; Touch | 1986 |
GABAB-receptor mediated inhibition of potassium-evoked release of endogenous 5-hydroxytryptamine from mouse frontal cortex.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Potassium; Receptors, GABA-A; Serotonin; Stereoisomerism | 1987 |
Adaptation of the GABAA-receptor complex in rat brain during chronic elevation of GABA by ethanolamine O-sulphate.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Chemistry; Ethanolamines; Flurazepam; gamma-Aminobutyric Acid; Muscimol; Nipecotic Acids; Pentobarbital; Picrotoxin; Potassium; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Modulation of GABA-gated chloride ion flux in rat brain by acute and chronic benzodiazepine administration.
Topics: Animals; Benzodiazepines; Brain; Chlorides; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains | 1988 |
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Electrophysiological actions of norepinephrine in rat lateral hypothalamus. II. An in vitro study of the effects of iontophoretically applied norepinephrine on LH neuronal responses to gamma-aminobutyric acid (GABA).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Drug Interactions; Drug Synergism; Female; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; In Vitro Techniques; Isoproterenol; Male; Neurons; Norepinephrine; Phenylephrine; Rats; Reference Values | 1988 |
Effects of pentobarbital and flurazepam on respiratory neurons in undrugged cats.
Topics: Animals; Cats; Decerebrate State; Electrophysiology; Flurazepam; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Respiratory System | 1987 |
Decreased effectiveness of GABA-mediated inhibition in the inferior colliculus of the genetically epilepsy-prone rat.
Topics: Animals; Bicuculline; Epilepsy; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Inferior Colliculi; Rats; Rats, Inbred Strains | 1986 |
The effects of benzodiazepine agonists, inverse agonists and Ro 15-1788 on the responses of the superior cervical ganglion to GABA in vitro.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Carbolines; Chlordiazepoxide; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
The action of gamma-aminobutyric acid (GABA) and ethylenediamine (EDA) on Limulus and Helix central neurones and rat cerebellar and sympathetic ganglion neurones.
Topics: Animals; Cerebellum; Ethylenediamines; Female; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Helix, Snails; Horseshoe Crabs; Neurons; Picrotoxin; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sesterterpenes | 1984 |
Pharmacological effects of benzodiazepines in the leech; benzodiazepine and GABA receptors and GABA level.
Topics: Animals; Anti-Anxiety Agents; Clorazepate Dipotassium; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Glutamine; Leeches; Lidocaine; Proteins; Receptors, Drug | 1980 |
Interactions between the benzodiazepines, methylxanthines, and adenosine.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Cerebral Cortex; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Theophylline | 1980 |
Effects of quazepam and flurazepam on GABA-ergic transmission in mouse cerebellum: relationship between biochemical and behavioral activity.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cerebellum; Cyclic GMP; Flurazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Intra-raphe benzodiazepines enhance rat locomotor activity: interactions with GABA.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Bicuculline; Brain Stem; Chlordiazepoxide; Dose-Response Relationship, Drug; Flurazepam; gamma-Aminobutyric Acid; Male; Midazolam; Motor Activity; Muscimol; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1983 |
Interactions between amino acid neurotransmitters and flurazepam in the neocortex of unanesthetized rats.
Topics: Amino Acids; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Neurotransmitter Agents; Rats; Rats, Inbred Strains | 1983 |
Specificity of GABA as a stimulator of dopamine release in rat substantia nigra.
Topics: Amino Acids; Animals; Dopamine; Flurazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Sodium; Structure-Activity Relationship; Substantia Nigra | 1980 |
A site for the potentiation of GABA-mediated responses by benzodiazepines.
Topics: Afferent Pathways; Animals; Bicuculline; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Ion Channels; Medulla Oblongata; Membrane Potentials; Muscimol; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1980 |
Electrophysiological studies of the mode of action of GABA on vertebrate central neurons.
Topics: Electric Conductivity; Flurazepam; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Mollusca; Motor Neurons; Neural Inhibition; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Synaptic Membranes | 1980 |
Chlordiazepoxide selectively potentiates GABA conductance of spinal cord and sensory neurons in cell culture.
Topics: Animals; Cells, Cultured; Chick Embryo; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Flurazepam; gamma-Aminobutyric Acid; Neurons; Spinal Cord; Synaptic Transmission; Time Factors | 1981 |
Drugs that increase gamma-aminobutyric acid transmission protect against the high pressure neurological syndrome.
Topics: Anesthetics; Animals; Bicuculline; Body Temperature; Flurazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Pressure; Seizures; Synaptic Transmission; Tremor; Valproic Acid | 1982 |
Comparison of norepinephrine- and benzodiazepine-induced augmentation of Purkinje cell responses to gamma-aminobutyric acid (GABA).
Topics: Animals; Binding Sites; Depression, Chemical; Desipramine; Drug Interactions; Female; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Norepinephrine; Purkinje Cells; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Synaptic Transmission | 1984 |
Role of the ventromedial nucleus of the thalamus in motor behaviour--I. Effects of focal injections of drugs.
Topics: Amino Acids; Amino Acids, Cyclic; Aminocaproates; Animals; Bicuculline; Corpus Striatum; Cyclohexanecarboxylic Acids; Flurazepam; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission; Thalamic Nuclei; Vigabatrin | 1983 |
Electrophysiological studies on benzodiazepine antagonists.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Carbolines; Cells, Cultured; Electric Stimulation; Electrophysiology; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Indoles; Neural Inhibition; Neurons; Rats; Rats, Inbred Strains | 1984 |
Caffeine-induced potentiation of GABA effects on frog spinal cord: an electrophysiological study.
Topics: Animals; Caffeine; Drug Synergism; Electric Conductivity; Flurazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; Motor Neurons; Rana temporaria; Spinal Cord | 1983 |
Nigral actions of GABA agonists are enhanced by chronic fluphenazine and differentiated by concomitant flurazepam.
Topics: Animals; Baclofen; Bicuculline; Female; Fluphenazine; Flurazepam; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1982 |
Interactions between dopamine and gamma-aminobutyrate in the substantia nigra: implications for the striatonigral output hypothesis.
Topics: Amino Acids; Amino Acids, Cyclic; Aminocaproates; Animals; Apomorphine; Bicuculline; Corpus Striatum; Cyclohexanecarboxylic Acids; Dopamine; Ethanolamines; Female; Flurazepam; gamma-Aminobutyric Acid; Locomotion; Male; Neural Pathways; Procaine; Rats; Rats, Inbred Strains; Substantia Nigra; Thalamus; Vigabatrin | 1983 |
Multiple actions of picomolar concentrations of flurazepam on the excitability of cultured mouse spinal neurons.
Topics: Animals; Anticonvulsants; Cell Membrane; Cells, Cultured; Electric Conductivity; Flurazepam; gamma-Aminobutyric Acid; Mice; Neurons; Picrotoxin; Spinal Cord | 1982 |
Flurazepam effects on rat cerebellar Purkinje cells.
Topics: Action Potentials; Animals; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Purkinje Cells; Rats | 1982 |
A comparison of the effects of flurazepam on gamma-aminobutyric acid mediated depression of cerebellar and cerebral cortical neurons.
Topics: Action Potentials; Animals; Cerebellum; Cerebral Cortex; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Neural Conduction; Purkinje Cells; Rats | 1981 |
Reduction of GABA-mediated inhibitory postsynaptic potentials in hippocampal CA1 pyramidal neurons following oral flurazepam administration.
Topics: Acetates; Acetic Acid; Anesthetics, Local; Animals; Depression, Chemical; Electric Stimulation; Electrophysiology; Evoked Potentials; Flurazepam; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Lidocaine; Male; Organophosphorus Compounds; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Channels; Synapses | 1995 |
Zinc inhibition of GABA-stimulated Cl- influx in rat brain regions is unaffected by acute or chronic benzodiazepine.
Topics: Animals; Benzodiazepines; Brain Chemistry; Chlorides; Chlorine; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc | 1994 |
Chronic benzodiazepine agonist treatment produces functional uncoupling of the gamma-aminobutyric acid-benzodiazepine receptor ionophore complex in cortical neurons.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Chloride Channels; Female; Flumazenil; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Macromolecular Substances; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Receptors, GABA; Receptors, GABA-A | 1994 |
Characterization of substantia nigra pars reticulata neurons based on response to iontophoretically applied GABA and flurazepam.
Topics: Action Potentials; Animals; Electrophysiology; Flurazepam; gamma-Aminobutyric Acid; Iontophoresis; Male; Neurons; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors | 1993 |
Tolerance to the effects of diazepam, clonazepam and bretazenil on GABA-stimulated Cl- influx in flurazepam tolerant rats.
Topics: Animals; Benzodiazepinones; Chloride Channels; Clonazepam; Diazepam; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1993 |
Properties of GABA-mediated synaptic potentials induced by zinc in adult rat hippocampal pyramidal neurones.
Topics: Action Potentials; Animals; Bicuculline; Culture Techniques; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Pentobarbital; Picrotoxin; Rats; Synapses; Synaptic Transmission; Zinc | 1993 |
GABAA receptor-induced inhibition of neuronal burst firing is weak in rat somatosensory cortex.
Topics: Animals; Baclofen; Flurazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Somatosensory Cortex | 1993 |
Developmental expression of functional GABAA receptors containing the gamma 2 subunit in neurons derived from embryonal carcinoma (P19) cells.
Topics: Amino Acid Sequence; Animals; Antibodies; Base Sequence; Carcinoma, Embryonal; Cell Differentiation; Cell Line; DNA Primers; Flurazepam; gamma-Aminobutyric Acid; Gene Expression; Kinetics; Macromolecular Substances; Membrane Potentials; Mice; Molecular Sequence Data; Neurons; Patch-Clamp Techniques; Peptide Fragments; Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Stem Cells; Time Factors; Tretinoin; Tumor Cells, Cultured | 1996 |
Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells.
Topics: Animals; Anti-Anxiety Agents; Drug Tolerance; Electrophysiology; Excitatory Postsynaptic Potentials; Flurazepam; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Male; Membrane Potentials; Neural Conduction; Patch-Clamp Techniques; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Synapses; Zolpidem | 1999 |
GABA receptors inhibited by benzodiazepines mediate fast inhibitory transmission in the central amygdala.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Bicuculline; Evoked Potentials; Flurazepam; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Neurons; Nipecotic Acids; Nitrazepam; Oximes; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Strychnine; Synaptic Transmission | 1999 |
Effects of striatal injections of GABA(A) receptor agonists and antagonists in a genetic animal model of paroxysmal dystonia.
Topics: Animals; Bicuculline; Binding Sites; Corpus Striatum; Cricetinae; Dystonia; Female; Flumazenil; Flurazepam; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Mesocricetus; Microinjections; Muscimol; Pentylenetetrazole; Phenobarbital | 2002 |
Effects of benzodiazepines on frog ERG.
Topics: Animals; Benzodiazepines; Bicuculline; Electroretinography; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Rana ridibunda; Retina | 2003 |
Clustering of extrasynaptic GABA(A) receptors modulates tonic inhibition in cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Nipecotic Acids; Nocodazole; Oximes; Protein Subunits; Rats; Receptors, GABA-A; Tetrodotoxin | 2004 |
Presynaptic source of quantal size variability at GABAergic synapses in rat hippocampal neurons in culture.
Topics: Animals; Cells, Cultured; Dextrans; Electric Stimulation; Evoked Potentials; Flurazepam; gamma-Aminobutyric Acid; Hippocampus; Neurons; Quantum Theory; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 2004 |
GABAergic signaling at mossy fiber synapses in neonatal rat hippocampus.
Topics: Action Potentials; Aminobutyrates; Animals; Animals, Newborn; Bicuculline; Cation Transport Proteins; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Agonists; Flurazepam; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Mossy Fibers, Hippocampal; Nipecotic Acids; Oximes; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, GABA-A; Synaptic Transmission; Vesicular Glutamate Transport Protein 1 | 2006 |
Benzodiazepine receptor agonists affect both binding and gating of recombinant alpha1beta2gamma2 gamma-aminobutyric acid-A receptors.
Topics: Allosteric Regulation; Binding Sites; Cell Line, Transformed; Dose-Response Relationship, Drug; Flurazepam; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Membrane Potentials; Patch-Clamp Techniques; Pyridines; Receptors, GABA-A; Recombinant Proteins; Transfection; Zolpidem | 2007 |
GABA transient sets the susceptibility of mIPSCs to modulation by benzodiazepine receptor agonists in rat hippocampal neurons.
Topics: Animals; Cells, Cultured; Electrophysiology; Flurazepam; GABA Modulators; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; Receptors, Neurotransmitter; Synaptic Transmission; Zolpidem | 2007 |
Flurazepam effect on GABAergic currents depends on extracellular pH.
Topics: Animals; Electrophysiology; Excitatory Postsynaptic Potentials; Extracellular Space; Flurazepam; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Models, Neurological; Patch-Clamp Techniques; Rats; Rats, Wistar; Synaptic Transmission | 2008 |
17beta-estradiol affects GABAergic transmission in developing hippocampus.
Topics: Age Factors; Aging; Animals; Drug Administration Schedule; Estradiol; Excitatory Amino Acid Antagonists; Female; Flurazepam; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Male; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Up-Regulation | 2008 |
Disulphide trapping of the GABA(A) receptor reveals the importance of the coupling interface in the action of benzodiazepines.
Topics: Animals; Benzodiazepines; Carbolines; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Flurazepam; gamma-Aminobutyric Acid; Hydrogen Peroxide; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Xenopus laevis | 2011 |
Comparison of kinetic and pharmacological profiles of recombinant α1γ2L and α1β2γ2L GABAA receptors - A clue to the role of intersubunit interactions.
Topics: Electrophysiological Phenomena; Flurazepam; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Kinetics; Protein Binding; Protein Subunits; Receptors, GABA-A; Recombinant Proteins | 2016 |