fluphenazine and prochlorperazine

fluphenazine has been researched along with prochlorperazine in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199056 (81.16)18.7374
1990's1 (1.45)18.2507
2000's2 (2.90)29.6817
2010's8 (11.59)24.3611
2020's2 (2.90)2.80

Authors

AuthorsStudies
Hulshoff, A; Perrin, JH1
Kalus, S; Mayausky, JS; McCreery, RL; Sackett, PH; Smith, T1
Pajeva, I; Wiese, M1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Kolaczkowska, A; Kolaczkowski, M; Michalak, K; Motohashi, N1
Brincat, JP; Carosati, E; Cruciani, G; Fravolini, A; Kaatz, GW; Manfroni, G; Patel, D; Raygada, JL; Sabatini, S1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rise, A1
Davis, JM; Gosenfeld, L; Tsai, CC1
Gruen, PH; Halpern, FS; Langer, G; Sachar, EJ1
Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF1
Feinberg, AP; Snyder, SH1
Baker, GA; Blumenstein, J; Santalo, R1
Frisk-Holmberg, M; van der Kleijn, E1
Johri, MB; Saxena, PN1
De Leenheer, A; Heyndrickx, A2
Breyer, U; Gaertner, HJ2
Manian, AA; Palmer, GC2
Gouret, C; Raynaud, G1
Brody, TM; Davis, PW1
Gayral, L1
Blazek, J; Krácmar, J1
Brois, A; Nelson, E; Trmal, T1
Coret, IA; Hughes, MJ1
Bertele, R; Breyer, U; Gaertner, HJ; Prox, A1
Breyer, U; Gaertner, HJ; Liomin, G1
Breyer, U; Gaertner, HJ; Prox, A1
Vichi, F1
Vinar, O1
Goldberg, LI; Yeh, BK1
Hadwiger, LA; Martin, AR1
Chang, CT; Huang, CL1
Madalena, JC1
Hanlon, TE; Kurland, AA; Michaux, MH; Ota, KY; Shaffer, JW1
Agarwal, SP; Blake, MI1
Felmeister, A; Tolat, SV1
Book, MH; Moore, MT1
Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH1
Merlis, S; White, L; Wolpert, A; Yaryura-Tobias, JA1
Noirfalise, A1
Dresse, A1
Cottom, DG; Newman, CG1
Bini, R1
Mao, TS; Noval, JJ1
Benmaman, JD; Plein, EM; Sorby, DL1
Boissier, JR; Lwoff, JM; Simon, P1
Merlis, S; Sheppard, C1
Abdou, FA1
MCQUEEN, EG1
DUNDEE, JW; LOVE, WJ; MOORE, J1
BIALY, HS; SEEMAN, PM1
BOHACEK, N; HAJNSEK, F; SARTORIUS, N1
COSGROVE, FP; DELGADO, JN; ISAACSON, EI1
WELSH, AL1
HANLON, TE; KURLAND, AA; MICHAUX, MH; OTA, KY1
BIRKETT, DP; GANTZ, RS1
GOBLE, JL; MARGOLIS, LH1
CLARKE, RS; DUNDEE, JW; LOVE, WJ; MOORE, J; NICHOLL, RM1
Beberok, A; Buszman, E; Otręba, M; Wrześniok, D1
Kośmider, L; Otręba, M1
Kośmider, L; Otręba, M; Rzepecka-Stojko, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Reviews

7 review(s) available for fluphenazine and prochlorperazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Maintenance antipsychotic drugs do prevent relapse: a reply to Tobias and MacDonald.
    Psychological bulletin, 1976, Volume: 83, Issue:3

    Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Drug Evaluation; Fluphenazine; Humans; Perphenazine; Placebos; Prochlorperazine; Recurrence; Research Design; Schizophrenia; Substance Withdrawal Syndrome; Thioridazine; Trifluoperazine

1976
[Neuroleptics in experimental teratogenesis].
    Rivista italiana di stomatologia, 1968, Volume: 23, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chlorpromazine; Fluphenazine; Haloperidol; Mice; Prochlorperazine; Rats; Reserpine; Tranquilizing Agents

1968
[Differential indication for the use of neuroleptics].
    Activitas nervosa superior, 1970, Jan-12, Volume: 12, Issue:1

    Topics: Acetaminophen; Chlorpromazine; Drug Synergism; Fluphenazine; Hallucinations; Humans; Imipramine; Methods; Paranoid Disorders; Placebos; Prochlorperazine; Schizophrenia; Socioeconomic Factors; Thioridazine; Tranquilizing Agents

1970
THE NEWER TRANQUILIZING DRUGS.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Chlorpromazine; Fluphenazine; Humans; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Rauwolfia; Reserpine; Thioridazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine

1964
In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review.
    Journal of applied toxicology : JAT, 2021, Volume: 41, Issue:1

    Topics: Antineoplastic Agents; Antipsychotic Agents; Dopamine Antagonists; Drug Repositioning; Fluphenazine; Humans; In Vitro Techniques; Neoplasms; Perphenazine; Prochlorperazine

2021
Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review.
    European journal of pharmacology, 2020, Nov-15, Volume: 887

    Topics: Animals; Antipsychotic Agents; Antiviral Agents; Betacoronavirus; Chlorpromazine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Fluphenazine; Humans; Pandemics; Perphenazine; Phenothiazines; Pneumonia, Viral; Prochlorperazine; RNA Viruses; SARS-CoV-2; Thioridazine

2020

Trials

2 trial(s) available for fluphenazine and prochlorperazine

ArticleYear
Tardive dyskinesia treated with pimozide.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:4

    Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine

1975
The comparative effectiveness of eight phenothiazines.
    Psychopharmacologia, 1965, Feb-15, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Female; Fluphenazine; Humans; Male; Middle Aged; Perphenazine; Prochlorperazine; Psychological Tests; Psychotic Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine

1965

Other Studies

60 other study(ies) available for fluphenazine and prochlorperazine

ArticleYear
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:3

    Topics: Binding Sites; Chromatography, Thin Layer; Circular Dichroism; Kinetics; Mathematics; Phenothiazines; Protein Binding; Serum Albumin, Bovine; Solubility; Sulfathiazoles

1977
Side-chain effects on phenothiazine cation radical reactions.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:11

    Topics: Cations; Chemical Phenomena; Chemistry; Phenothiazines

1981
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
    Journal of medicinal chemistry, 1998, May-21, Volume: 41, Issue:11

    Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured

1998
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:4

    Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Fluphenazine; Fungal Proteins; Ketoconazole; Membrane Transport Proteins; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2009
Discovery of novel inhibitors of the NorA multidrug transporter of Staphylococcus aureus.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzimidazoles; Ciprofloxacin; Databases, Factual; Drug Resistance, Bacterial; Drug Synergism; Ethidium; Microbial Sensitivity Tests; Models, Molecular; Multidrug Resistance-Associated Proteins; Phenyl Ethers; Propanolamines; Quantitative Structure-Activity Relationship; Staphylococcus aureus; Structure-Activity Relationship; Sulfonamides

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
[Neuroleptics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-10, Volume: 96, Issue:7

    Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenazine; Haloperidol; Humans; Maternal-Fetal Exchange; Perphenazine; Pregnancy; Prochlorperazine; Teratogens; Thioridazine; Triflupromazine

1976
Human prolactin responses to neuroleptic drugs correlate with antischizophrenic potency.
    Nature, 1977, Apr-14, Volume: 266, Issue:5603

    Topics: Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Humans; Male; Perphenazine; Prochlorperazine; Prolactin; Schizophrenia; Synaptic Transmission; Thiothixene; Tranquilizing Agents; Trifluoperazine

1977
Phenothiazine drugs: structure-activity relationships explained by a conformation that mimics dopamine.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:5

    Topics: Antipsychotic Agents; Chlorpromazine; Computers; Dopamine; Fluphenazine; Models, Molecular; Molecular Conformation; Perphenazine; Prochlorperazine; Promazine; Structure-Activity Relationship; Thiethylperazine; Trifluoperazine; Triflupromazine

1975
Effect of psychotropic agents upon the blastogenic response of human t-lymphocytes.
    Biological psychiatry, 1977, Volume: 12, Issue:2

    Topics: Chlorpromazine; Depression, Chemical; DNA; Dopamine; Doxepin; Drug Synergism; Fluphenazine; Haloperidol; Humans; In Vitro Techniques; Lymphocyte Activation; Osmolar Concentration; Prochlorperazine; Proteins; RNA; T-Lymphocytes; Thiothixene; Thymidine; Tranquilizing Agents; Trifluoperazine; Uridine

1977
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine

1972
Antagonistic activity of some phenothiazine derivatives against neurohumoral transmitters.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Female; Fluphenazine; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Neurotransmitter Agents; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rabbits; Rats; Receptors, Adrenergic; Serotonin Antagonists; Thioridazine; Trifluoperazine; Triflupromazine; Trimeprazine

1973
Identification of phenothiazine derivatives and analogs by x-ray diffraction. I. Examination of pure compounds.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:3

    Topics: Acepromazine; Chlorpromazine; Evaluation Studies as Topic; Fluphenazine; Fumarates; Maleates; Malonates; Mathematics; Methods; Organophosphorus Compounds; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Sulfoxides; Thioridazine; Trifluoperazine; Triflupromazine; X-Ray Diffraction

1971
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
    Journal - Association of Official Analytical Chemists, 1971, Volume: 54, Issue:3

    Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction

1971
Tissue accumulation of metabolites during chronic administration of piperazine-substituted phenothiazine drugs.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Amines; Animals; Antipsychotic Agents; Brain; Chromatography, Thin Layer; Dealkylation; Ethylenediamines; Female; Fluphenazine; Humans; Kidney; Liver; Male; Mass Spectrometry; Mental Disorders; Perphenazine; Piperazines; Prochlorperazine; Species Specificity; Sulfoxides; Time Factors; Trifluoperazine

1974
Modification of the receptor component of adenylate cyclase in the rat brain by phenothiazine derivatives.
    Neuropharmacology, 1974, Volume: 13, Issue:9

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Fluphenazine; Haloperidol; Hydroxylation; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Perphenazine; Prochlorperazine; Promazine; Rats; Receptors, Drug; Thiothixene; Tritium

1974
[Activity of various neuroleptics after single repeated treatment in the mice submitted to the four plate test and the escape test].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1974, Volume: 168, Issue:2-3

    Topics: Animals; Chlorpromazine; Chlorprothixene; Diazepam; Drug Evaluation, Preclinical; Electroshock; Escape Reaction; Fluphenazine; Haloperidol; Methotrimeprazine; Mice; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluperidol

1974
Effects of phenothiazines and phenothiazine metabolites on adenyl cyclase and the cyclic AMP response in the rat brain.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Enzyme Activation; Fluphenazine; Haloperidol; Hydroxylation; Hypothalamus; In Vitro Techniques; Male; Neuroglia; Neurons; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine

1974
Inhibition of Na+K+-activated adenosine triphosphatase activity in rat brain by substituted phenothiazines.
    Biochemical pharmacology, 1966, Volume: 15, Issue:6

    Topics: Adenosine Triphosphatases; Aminobutyrates; Animals; Brain; Chlorpromazine; Dextroamphetamine; Fluphenazine; Imipramine; In Vitro Techniques; Microsomes; Pentobarbital; Pentylenetetrazole; Perphenazine; Phenothiazines; Potassium; Prochlorperazine; Promazine; Promethazine; Rats; Sodium; Strychnine; Thiethylperazine; Thioridazine; Trifluoperazine; Triflupromazine

1966
[Delayed-action neuroleptics. Indications and technic of use].
    Semaine therapeutique, 1968, Volume: 44, Issue:10

    Topics: Delayed-Action Preparations; Fluphenazine; Humans; Phenothiazines; Prochlorperazine; Schizophrenia; Tranquilizing Agents

1968
[UV-spectrophotometry in drug control. 7. Effect of substitution and the solvents on the UV-spectrophotometric behavior of drugs with phenothiazine-chromophore].
    Die Pharmazie, 1968, Volume: 23, Issue:11

    Topics: Acepromazine; Chlorpromazine; Ethanol; Fluphenazine; Hydrochloric Acid; Methanol; Methotrimeprazine; Parasympatholytics; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Solvents; Spectrophotometry; Thiethylperazine; Thioridazine; Trifluoperazine; Ultraviolet Rays; Water

1968
Effects of some phenothiazines on unilateral ovarian compensatory hypertrophy in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Animals; Castration; Chemical Phenomena; Chemistry; Chlorpromazine; Female; Fluphenazine; Hypertrophy; Hypothalamo-Hypophyseal System; Methotrimeprazine; Organ Size; Ovarian Diseases; Perphenazine; Phenothiazines; Pituitary Gland; Prochlorperazine; Promazine; Rats; Thioridazine; Trifluoperazine; Trimeprazine

1969
In vivo piperazine ring degradation in neuroleptic and antihistaminic drugs.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:6

    Topics: Animals; Biotransformation; Dogs; Ethylenediamines; Female; Fluphenazine; Histamine H1 Antagonists; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Rats; Rats, Inbred Strains; Tranquilizing Agents; Trifluoperazine

1972
Effects of tricyclic compounds on the histamine response of isolated atria.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Dose-Response Relationship, Drug; Female; Fluphenazine; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Imipramine; In Vitro Techniques; Male; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Rabbits; Thioridazine; Time Factors; Triflupromazine

1974
Tissue metabolites of trifluoperazine, fluphenazine, prochlorperazine, and perphenazine in the rat: indentification and synthesis.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:12

    Topics: Animals; Biodegradation, Environmental; Biotransformation; Chromatography, Thin Layer; Fluphenazine; Kidney; Liver; Lung; Male; Mass Spectrometry; Perphenazine; Prochlorperazine; Rats; Trifluoperazine

1974
Metabolism of trifluoperazine, fluphenazine, prochlorperazine and perphenazine in rats: in vitro and urinary metabolites.
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Chromatography, Thin Layer; Dealkylation; Fluphenazine; Hydroxylation; Male; Microsomes, Liver; Oxidation-Reduction; Oxides; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Rats; Spectrophotometry, Ultraviolet; Sulfoxides; Trifluoperazine

1974
Formation of identical metabolites from piperazine- and dimethylamino-substituted phenothiazine drugs in man, rat and dog.
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Biotransformation; Chlorpromazine; Chromatography, Thin Layer; Dimethylamines; Dogs; Female; Fluphenazine; Humans; Male; Mass Spectrometry; Methylation; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Promazine; Propylamines; Rats; Sulfoxides; Trifluoperazine; Triflupromazine

1974
Attenuation of dopamine-induced renal vasodilation in the dog by phenothiazines.
    European journal of pharmacology, 1971, Volume: 15, Issue:1

    Topics: Animals; Bradykinin; Chlorpromazine; Dopamine; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Humans; Male; Phenothiazines; Prochlorperazine; Receptors, Drug; Regional Blood Flow; Renal Artery; Thioridazine; Trifluoperazine; Vasodilator Agents

1971
Induced formation of phenylalanine ammonia lyase and pisatin by chlorpromazine and other phenothiazine derivatives.
    Biochemical pharmacology, 1971, Volume: 20, Issue:12

    Topics: Carbon Isotopes; Chlorpromazine; Cycloheximide; Deamination; Enzyme Induction; Fluphenazine; Lectins; Leucine; Lyases; Perphenazine; Phenothiazines; Phenylalanine; Plant Lectins; Plant Proteins; Plants, Edible; Prochlorperazine; Promazine; Promethazine; Purines; RNA; Stimulation, Chemical; Structure-Activity Relationship; Thioridazine; Trifluoperazine; Triflupromazine

1971
Physical properties of quaternary ammonium salts of phenothiazine derivatives.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:12

    Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Fluphenazine; Infrared Rays; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Spectrum Analysis; Triflupromazine; Ultraviolet Rays

1971
[Preliminary tests with injectable biperiden in the treatment of neurodysleptic crises induced by neuroleptic drugs].
    Hospital (Rio de Janeiro, Brazil), 1969, Volume: 76, Issue:2

    Topics: 1-Propanol; Adolescent; Adult; Biperiden; Fluphenazine; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Parasympatholytics; Piperidines; Prochlorperazine; Schizophrenia; Tranquilizing Agents

1969
Analysis of certain phenothiazines and their dosage forms by photometric titration with ceric sulfate.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:8

    Topics: Chlorpromazine; Colorimetry; Dosage Forms; Fluphenazine; Methods; Perphenazine; Pharmacopoeias as Topic; Phenothiazines; Photometry; Prochlorperazine; Solutions; Spectrophotometry; Tablets; Trifluoperazine; Trimeprazine; Ultraviolet Rays

1969
Phospholipid spherules as a model to assess photosensitizing properties of drugs.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:6

    Topics: Chlorpromazine; Chromates; Fluphenazine; Models, Chemical; Phenothiazines; Phospholipids; Photosensitivity Disorders; Prochlorperazine; Promazine; Radiation Effects; Spectrophotometry; Triflupromazine; Ultraviolet Rays

1970
Sudden death in phenothiazine therapy. (A clinicopathologic study of 12 cases).
    The Psychiatric quarterly, 1970, Volume: 44, Issue:3

    Topics: Adolescent; Adult; Aged; Asphyxia; Autopsy; Brain; Brain Diseases; Chlorpromazine; Death, Sudden; Drug Synergism; Electrocardiography; Female; Fluphenazine; Heart Diseases; Humans; Kidney; Liver; Lung; Male; Mental Disorders; Middle Aged; Myocardium; Perphenazine; Phenothiazines; Prochlorperazine; Schizophrenia; Spleen; Thioridazine; Tranquilizing Agents; Triflupromazine

1970
Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:7

    Topics: Acepromazine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benperidol; Chlorpromazine; Chlorprothixene; Fluphenazine; Haloperidol; Male; Mastication; Methods; Motor Activity; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rats; Thiazines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1967
Triiodothyronine and phenothiazines in schizophrenia.
    Diseases of the nervous system, 1969, Volume: 30, Issue:7

    Topics: Adult; Chlorpromazine; Female; Fluphenazine; Humans; Male; Middle Aged; Phenothiazines; Prochlorperazine; Schizophrenia; Thioridazine; Trifluoperazine; Triiodothyronine

1969
[Demonstration of some phenothiazine derivatives by thin-layer chromatography on silica gel].
    Journal of chromatography, 1965, Volume: 19, Issue:1

    Topics: Chlorpromazine; Chromatography, Thin Layer; Fluphenazine; Methotrimeprazine; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Thioridazine

1965
[Influence of 15 neuroleptics (butyrophenones and phenothiazines) on changes in noradrenaline content of the brain and activity of the rat in the self stimulation test].
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 159, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Butyrophenones; Chlorpromazine; Chlorprothixene; Fluphenazine; Methotrimeprazine; Norepinephrine; Phenothiazines; Prochlorperazine; Rats; Self Stimulation; Tranylcypromine

1966
Dystonic reactions to phenothiazine derivatives.
    Archives of disease in childhood, 1966, Volume: 41, Issue:219

    Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Female; Fluphenazine; Humans; Male; Muscular Diseases; Prochlorperazine

1966
[Accidental poisoning caused by phenothiazines in childhood. (Considerations presentation of 9 cases)].
    Rivista di clinica pediatrica, 1966, Volume: 78, Issue:6

    Topics: Child; Child, Preschool; Female; Fluphenazine; Humans; Infant; Male; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine

1966
Some relationships concerning the chemical structure, hemolytic activity, and therapeutic potency of phenothiazines.
    Biochemical pharmacology, 1966, Volume: 15, Issue:4

    Topics: Animals; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Erythrocytes; Fluphenazine; Hemolysis; In Vitro Techniques; Methotrimeprazine; Phenothiazines; Prochlorperazine; Promazine; Sheep; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine

1966
Adsorption of phenothiazine derivatives by solid adsorbents.
    Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:8

    Topics: Acepromazine; Adsorption; Charcoal; Chlorpromazine; Fluphenazine; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kaolin; Muscles; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Sodium Chloride; Spectrophotometry; Talc; Temperature; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine; Ultraviolet Rays

1966
[Pharmacologic studies of a prolonged action neuroleptic: fluphenazine enanthate].
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 14, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Chloral Hydrate; Dextroamphetamine; Drug Synergism; Fluphenazine; Male; Mice; Pentobarbital; Prochlorperazine; Rats

1966
Drug-induced extrapyramidal symptoms: their incidence and treatment.
    The American journal of psychiatry, 1967, Volume: 123, Issue:7

    Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasympatholytics; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluoperazine

1967
Psychotropic drug therapy in children and adolescents.
    Virginia medical monthly, 1967, Volume: 94, Issue:8

    Topics: Adolescent; Antidepressive Agents; Child; Child Behavior Disorders; Chlorpromazine; Dextroamphetamine; Fluphenazine; Humans; Imipramine; Intellectual Disability; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine

1967
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
    The New Zealand medical journal, 1963, Volume: 62

    Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundice; New Zealand; Perphenazine; Phenothiazines; Poisoning; Pregnancy; Pregnancy Complications; Prochlorperazine; Promazine; Thioridazine; Toxicology; Trifluoperazine; Triflupromazine; Trimeprazine

1963
ALTERATIONS IN RESPONSE TO SOMATIC PAIN ASSOCIATED WITH ANAESTHESIA. XV. FURTHER STUDIES WITH PHENOTHIAZINE DERIVATIVES AND SIMILAR DRUGS.
    British journal of anaesthesia, 1963, Volume: 35

    Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Antiemetics; Antipyretics; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Nociceptive Pain; Pain; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Trifluoperazine; Triflupromazine; Trimeprazine

1963
THE SURFACE ACTIVITY OF TRANQUILIZERS.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Antipsychotic Agents; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Imipramine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Research; Reserpine; Surface Tension; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1963
[EXTRAPYRAMIDAL SYMPTOMS DUE TO THE USE OF PSYCHOPHARMACA].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1963, Volume: 31

    Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Fluphenazine; Imipramine; Methotrimeprazine; Monoamine Oxidase Inhibitors; Parkinsonian Disorders; Phenothiazines; Prochlorperazine; Promazine; Psychopharmacology; Rauwolfia; Sympathomimetics; Thioridazine; Toxicology; Tranquilizing Agents; Trifluoperazine

1963
PHENOTHIAZINE DERIVATIVES.
    Texas state journal of medicine, 1964, Volume: 60

    Topics: Chlorpromazine; Fluphenazine; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Toxicology; Trifluoperazine; Triflupromazine

1964
PHENOTHIAZINES IN THE TREATMENT OF NEWLY ADMITTED STATE HOSPITAL PATIENTS: GLOBAL COMPARISON OF EIGHT COMPOUNDS IN TERMS OF AN OUTCOME INDEX.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Biomedical Research; Chlorpromazine; Drug Therapy; Fluphenazine; Hospitals, State; Humans; Mental Disorders; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine

1964
PHENOTHIAZINE REDUCTION AS A CAUSE OF REHOSPITALIZATION.
    Archives of general psychiatry, 1965, Volume: 12

    Topics: Chlorpromazine; Drug Therapy; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; Prochlorperazine; Prognosis; Promazine; Schizophrenia; Statistics as Topic; Substance Withdrawal Syndrome; Thioridazine; Tranquilizing Agents; Trifluoperazine

1965
LENTICULAR OPACITIES WITH PROLONGED PHENOTHIAZINE THERAPY: A POTENTIAL HAZARD WITH ALL PHENOTHIAZINE DERIVATIVES.
    JAMA, 1965, Jul-05, Volume: 193

    Topics: Antipsychotic Agents; Cataract; Chlorpromazine; Drug Therapy; Fluphenazine; Phenothiazines; Prochlorperazine; Schizophrenia; Toxicology; Trifluoperazine

1965
STUDIES OF DRUGS GIVEN BEFORE ANAESTHESIA. VI. THE PHENOTHIAZINE DERIVATIVES.
    British journal of anaesthesia, 1965, Volume: 37

    Topics: Anesthesia; Anesthesia, General; Atropine; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Meperidine; Methohexital; Methotrimeprazine; Nitrous Oxide; Oxygen; Perphenazine; Pharmacology; Phenothiazines; Preanesthetic Medication; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine

1965
In vitro melanogenesis inhibition by fluphenazine and prochlorperazine in normal human melanocytes lightly pigmented.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2018, Volume: 26, Issue:1

    Topics: Cell Survival; Cells, Cultured; Fluphenazine; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Prochlorperazine

2018
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016