fluphenazine has been researched along with perphenazine in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 102 (73.91) | 18.7374 |
| 1990's | 6 (4.35) | 18.2507 |
| 2000's | 13 (9.42) | 29.6817 |
| 2010's | 14 (10.14) | 24.3611 |
| 2020's | 3 (2.17) | 2.80 |
| Authors | Studies |
|---|---|
| Hulshoff, A; Perrin, JH | 1 |
| Kalus, S; Mayausky, JS; McCreery, RL; Sackett, PH; Smith, T | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Pajeva, I; Wiese, M | 1 |
| Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Geffen, Y; Gil-Ad, I; Nudelman, A; Rephaeli, A; Ron, H; Savitsky, K; Shpaisman, N; Terasenko, I; Weizman, A | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Kolaczkowska, A; Kolaczkowski, M; Michalak, K; Motohashi, N | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Rise, A | 1 |
| Davis, JM; Gosenfeld, L; Tsai, CC | 1 |
| Dencker, SJ | 1 |
| Bowers, MB; Nelson, JC | 1 |
| Charney, DS; Kales, A; Nelson, JC; Soldatos, CR | 1 |
| Gruen, PH; Halpern, FS; Langer, G; Sachar, EJ | 1 |
| Calne, DB; Claveria, LE; Haskayne, L; Lodge-Patch, IC; Pallis, CA; Petrie, A; Teychenne, PF | 1 |
| Obukhov, GA | 1 |
| Feinberg, AP; Snyder, SH | 1 |
| Lankelma, J; Poppe, H; Tjaden, UR | 1 |
| Angst, J; Woggon, B | 1 |
| Henry, BW; Overall, JE; Woodward, JA | 1 |
| Swett, C | 1 |
| Itoh, H; Ogita, K; Yagi, G | 1 |
| Aravagiri, M; Chabert, N; Marder, SR; Van Putten, T; Wirshing, WC | 1 |
| Lu, RS; Peng, TZ; Yang, ZP | 1 |
| Kakigi, T; Kaneda, H; Shintani, T; Tanimoto, K; Terada, T | 1 |
| Curry, SH | 1 |
| Knudsen, P | 1 |
| Jauregui, J; Kelley, AE; Nadaud, D; Stinus, L | 1 |
| Anderson, JL; Belal, F | 1 |
| Bonato, RR; Galdi, J | 1 |
| Frisk-Holmberg, M; van der Kleijn, E | 1 |
| Taub, A | 1 |
| Johri, MB; Saxena, PN | 1 |
| De Leenheer, A; Heyndrickx, A | 2 |
| Hollister, LE; Kimbell, I; Overall, JE; Pokorny, A | 1 |
| Gunby, B | 2 |
| Breyer, U; Gaertner, HJ | 2 |
| Stern, P; Valjevac, K | 2 |
| Greenberg, D; Snyder, S; Yamamura, HI | 1 |
| Manian, AA; Palmer, GC | 2 |
| Avrutskii, GIa; Gurovich, IIa; Prokhorova, IS; Romanov, IuD; Tirkel'taub, IuA | 1 |
| Gabay, S; Huang, PC | 1 |
| Gouret, C; Raynaud, G | 1 |
| Greenberg, D; Snyder, SH; Yamumura, HI | 1 |
| Mattsson, B; Persson, SA | 1 |
| Gabay, S; Harris, SR | 2 |
| Brody, TM; Davis, PW | 1 |
| Blazek, J; Krácmar, J | 1 |
| Stille, G | 2 |
| Brois, A; Nelson, E; Trmal, T | 1 |
| Coret, IA; Hughes, MJ | 1 |
| Bertele, R; Breyer, U; Gaertner, HJ; Prox, A | 1 |
| Nielsen, IM | 1 |
| Anderson, J; Lambert, NG; Pigott, PV | 1 |
| Bakke, O | 1 |
| Pigott, PV | 1 |
| Larsen, NE; Naestoft, J | 1 |
| Boeck, V; Christensen, AV; Fjalland, B; Franck, KF; Nielsen, IM; Nymark, M; Pedersen, V | 1 |
| Breyer, U; Gaertner, HJ; Liomin, G | 1 |
| Breyer, U; Gaertner, HJ; Prox, A | 1 |
| Kehoe, MJ | 1 |
| Garriott, JC; Stolman, A | 1 |
| Uno, M | 1 |
| Eckstein, B; Eylath, U; Givant, Y; Shani, J; Sulman, FG | 1 |
| Hadwiger, LA; Martin, AR | 1 |
| Chang, CT; Huang, CL | 1 |
| Haddenbrock, S | 1 |
| Hanlon, TE; Kurland, AA; Michaux, MH; Ota, KY; Shaffer, JW | 1 |
| Goldstein, BJ; Ravel, R; Riekers, HG | 1 |
| Janssen, PA; Niemegeers, CJ; Verbruggen, FJ | 2 |
| Agarwal, SP; Blake, MI | 1 |
| Núnek, K | 1 |
| Cowan, G; McClellan, TA | 1 |
| Book, MH; Moore, MT | 1 |
| Schipper, JA | 1 |
| Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH | 1 |
| Fox, JA; Irwin, S; Roth, FE; Taber, RI | 1 |
| Brophy, JJ | 1 |
| Noirfalise, A | 1 |
| Fieve, RR; Wharton, RN | 1 |
| Erickson, G; Forrest, FM; Geiter, CW; Laxson, GO; Snow, HL | 1 |
| Kofoed, J; Korczak-Fabierkiewicz, C; Lucas, GH | 1 |
| Greenfield, EJ; Lundy, RO; Potts, JL; Proctor, CD | 1 |
| Bini, R | 1 |
| Irwin, S | 1 |
| Merlis, S; Sheppard, C | 1 |
| Terry, PM | 1 |
| Brown, WA; Laughren, TP; Williams, B | 1 |
| Brown, WA; Chisholm, E; Laughren, T; Williams, BW | 1 |
| Aranovich, AG; Gamburg, AL; Rasniuk, VA; Vol'fson, VL | 1 |
| Guo, L; Kataoka, K; Katayama, H; Miki, T; Mizushima, T; Sekimizu, K; Shinpuku, T | 1 |
| Bindl, A; Eberlein-König, B; Przybilla, B | 1 |
| Aloisi, GG; Barbafina, A; Dall'Acqua, F; Elisei, F; Gabellini, N; Latterini, L; Vedaldi, D; Viola, G | 1 |
| DOBKIN, AB | 1 |
| DOBKIN, AB; PURKIN, N | 1 |
| MCQUEEN, EG | 1 |
| DUNDEE, JW; LOVE, WJ; MOORE, J | 1 |
| COSGROVE, FP; DELGADO, JN; ISAACSON, EI | 1 |
| WELSH, AL | 1 |
| HANLON, TE; KURLAND, AA; MICHAUX, MH; OTA, KY | 1 |
| MAASSJENSEN, N; PARADABRAVO, F | 1 |
| MORI, A; YABUKI, Y | 1 |
| DURUPT, L; PIATECKI, A | 1 |
| BIRKETT, DP; GANTZ, RS | 1 |
| CLARKE, RS; DUNDEE, JW; LOVE, WJ; MOORE, J; NICHOLL, RM | 1 |
| Andersen, J; Duncan, E; Dunlop, BW; Phillips, LS; Sternberg, M | 1 |
| Bastianon, C; Caffieri, S; Miolo, G; Reddi, E; Zanoni, R | 1 |
| Bastianon, C; Caffieri, S; Gallocchio, F; Levorato, L; Miolo, G; Reddi, E; Zanoni, R | 1 |
| Lu, J; Nie, F; Niu, W | 1 |
| Boshoven, W; Duncan, E; Dunlop, BW; Hamer, RM; Phillips, LS; Woolson, SL | 1 |
| Czernikiewicz, A; Kucharska-Pietura, K; Mortimer, A; Tylec, A | 1 |
| Chrisphonte, P; Ostroff, RB; Rosenheck, RA | 1 |
| Brown, PI; Johnson-Davis, KL; Juenke, JM; McMillin, GA; Urry, FM | 1 |
| Huang, J; Li, L; Xu, L; You, T | 1 |
| Johnson-Davis, KL; Slawson, MH | 1 |
| Gowda, R; Kuzu, OF; Noory, MA; Robertson, GP | 1 |
| Beberok, A; Buszman, E; Otreba, M; Rok, J; Wrześniok, D | 1 |
| Kośmider, L; Otręba, M | 1 |
| Kośmider, L; Otręba, M; Rzepecka-Stojko, A | 1 |
| Abdelhamid, NS; Anwar, BH; Farid, NF; Magdy, MA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
9 review(s) available for fluphenazine and perphenazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Maintenance antipsychotic drugs do prevent relapse: a reply to Tobias and MacDonald.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Drug Evaluation; Fluphenazine; Humans; Perphenazine; Placebos; Prochlorperazine; Recurrence; Research Design; Schizophrenia; Substance Withdrawal Syndrome; Thioridazine; Trifluoperazine | 1976 |
Neuroleptic plasma levels.
Topics: Antipsychotic Agents; Biological Availability; Chlorpromazine; Fluphenazine; Haloperidol; Humans; Perphenazine; Schizophrenia; Thiothixene | 1991 |
The strategy and value of neuroleptic drug monitoring.
Topics: Antipsychotic Agents; Chlorpromazine; Chromatography, Gas; Chromatography, Liquid; Fluphenazine; Forensic Medicine; Haloperidol; Humans; Patient Compliance; Perphenazine; Phenothiazines; Radioligand Assay; Schizophrenia; Thioridazine; Thiothixene; Trifluoperazine | 1985 |
Antischizophrenic drugs and brain cholinergic receptors. Affinity for muscarinic sites predicts extrapyramidal effects.
Topics: Animals; Antipsychotic Agents; Butyrophenones; Chemical Phenomena; Chemistry; Chlorpromazine; Dibenzazepines; Extrapyramidal Tracts; Fluphenazine; Haloperidol; Haplorhini; Humans; Perphenazine; Phenothiazines; Promazine; Rats; Receptors, Cholinergic; Schizophrenia; Thioridazine; Triflupromazine | 1974 |
II. Major tranquilizers.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Hematologic Diseases; Humans; Hypotension; Lithium; Perphenazine; Phenothiazines; Promazine; Promethazine; Psychopharmacology; Psychotic Disorders; Reserpine; Thiazines; Thioridazine; Tranquilizing Agents; Triflupromazine | 1971 |
THE NEWER TRANQUILIZING DRUGS.
Topics: Chlorpromazine; Fluphenazine; Humans; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Rauwolfia; Reserpine; Thioridazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine | 1964 |
In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review.
Topics: Antineoplastic Agents; Antipsychotic Agents; Dopamine Antagonists; Drug Repositioning; Fluphenazine; Humans; In Vitro Techniques; Neoplasms; Perphenazine; Prochlorperazine | 2021 |
Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review.
Topics: Animals; Antipsychotic Agents; Antiviral Agents; Betacoronavirus; Chlorpromazine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Fluphenazine; Humans; Pandemics; Perphenazine; Phenothiazines; Pneumonia, Viral; Prochlorperazine; RNA Viruses; SARS-CoV-2; Thioridazine | 2020 |
9 trial(s) available for fluphenazine and perphenazine
| Article | Year |
|---|---|
Tardive dyskinesia treated with pimozide.
Topics: Aged; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Consciousness Disorders; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Pimozide; Prochlorperazine; Promazine; Promethazine; Schizophrenia; Thioridazine | 1975 |
[Clinical study on five depot neuroleptics. Comparison of effective profiles of fluphenazinedecanoate, fluspirilene, penfluridol, perphenazine-enanthate and pipothiazinepalmitate].
Topics: Administration, Oral; Bipolar Disorder; Catatonia; Clinical Trials as Topic; Delayed-Action Preparations; Drug Evaluation; Female; Fluorobenzenes; Fluphenazine; Hallucinations; Hostility; Humans; Hydrocarbons, Halogenated; Hypochondriasis; Injections, Intramuscular; Methods; Paranoid Disorders; Perphenazine; Piperidines; Schizophrenia; Spiro Compounds; Sulfonamides; Time Factors; Tranquilizing Agents | 1975 |
Relationship of adverse drug reactions to length of hospital-stay in genetically subgrouped schizophrenics.
Topics: Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Dyskinesia, Drug-Induced; Fluphenazine; Humans; Length of Stay; Perphenazine; Random Allocation; Risk Factors; Schizophrenia; Schizophrenic Psychology | 1988 |
Specific indications for different classes of phenothiazines.
Topics: Adult; Age Factors; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Drug Evaluation; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; Psychiatric Status Rating Scales; Remission, Spontaneous; Schizophrenia; Schizophrenia, Paranoid; Schizophrenic Psychology; Thioridazine | 1974 |
An evaluation of fluphenazine with nortriptyline in anxiety and depression.
Topics: Amitriptyline; Anxiety; Clinical Trials as Topic; Depression; Drug Combinations; Fluphenazine; Humans; Nortriptyline; Perphenazine; Placebos | 1972 |
Clinical experience with depot neuroleptics.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Perphenazine; Psychotic Disorders; Sex Factors; Time Factors; Tranquilizing Agents | 1973 |
A review of clinical studies with combinations of fluphenazine and nortriptyline.
Topics: Amitriptyline; Anxiety; Central Nervous System; Clinical Trials as Topic; Depression; Diazepam; Doxepin; Drug Combinations; Fluphenazine; Heart Conduction System; Humans; Motor Activity; Nortriptyline; Perphenazine; Placebos; Psychiatric Status Rating Scales; Vision Disorders | 1972 |
The comparative effectiveness of eight phenothiazines.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Female; Fluphenazine; Humans; Male; Middle Aged; Perphenazine; Prochlorperazine; Psychological Tests; Psychotic Disorders; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine | 1965 |
[Depot-neuroleptics in the treatment of schizophrenia].
Topics: Adult; Chlorpromazine; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Perphenazine; Schizophrenia; Thioridazine | 1971 |
120 other study(ies) available for fluphenazine and perphenazine
| Article | Year |
|---|---|
Quantitative correlations between albumin binding constants and chromatographic Rm values of phenothiazine derivatives.
Topics: Binding Sites; Chromatography, Thin Layer; Circular Dichroism; Kinetics; Mathematics; Phenothiazines; Protein Binding; Serum Albumin, Bovine; Solubility; Sulfathiazoles | 1977 |
Side-chain effects on phenothiazine cation radical reactions.
Topics: Cations; Chemical Phenomena; Chemistry; Phenothiazines | 1981 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured | 1998 |
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
A mutual prodrug ester of GABA and perphenazine exhibits antischizophrenic efficacy with diminished extrapyramidal effects.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Biological Availability; Catalepsy; Dextroamphetamine; Dyskinesia, Drug-Induced; Esters; Fluphenazine; gamma-Aminobutyric Acid; Male; Perphenazine; Prodrugs; Prolactin; Rats; Rats, Wistar; Schizophrenia | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.
Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Fluphenazine; Fungal Proteins; Ketoconazole; Membrane Transport Proteins; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2009 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship | 2016 |
[Neuroleptics].
Topics: Abnormalities, Drug-Induced; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Female; Fluphenazine; Haloperidol; Humans; Maternal-Fetal Exchange; Perphenazine; Pregnancy; Prochlorperazine; Teratogens; Thioridazine; Triflupromazine | 1976 |
High-dose treatment with neuroleptics in the acute phase of mental disease.
Topics: Antipsychotic Agents; Flupenthixol; Fluphenazine; Haloperidol; Humans; Mental Disorders; Perphenazine; Time Factors | 1976 |
Delusional unipolar depression: description and drug response.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Delusions; Depression; Female; Fluphenazine; Haloperidol; Humans; Imipramine; Male; Middle Aged; Perphenazine; Thioridazine; Thiothixene | 1978 |
Somnambulistic-like episodes secondary to combined lithium-neuroleptic treatment.
Topics: Adolescent; Adult; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Drug Therapy, Combination; Epilepsy; Female; Fluphenazine; Haloperidol; Humans; Lithium; Male; Middle Aged; Perphenazine; Schizophrenia; Somnambulism; Thioridazine; Thiothixene | 1979 |
Human prolactin responses to neuroleptic drugs correlate with antischizophrenic potency.
Topics: Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Humans; Male; Perphenazine; Prochlorperazine; Prolactin; Schizophrenia; Synaptic Transmission; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1977 |
[Prolonged action neuroleptics (review of the foreign literature)].
Topics: Acute Disease; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Child; Chronic Disease; Delayed-Action Preparations; Dibenzazepines; Dibenzothiepins; Dosage Forms; Drug Therapy, Combination; Fluphenazine; Humans; Paranoid Disorders; Perphenazine; Pimozide; Piperazines; Piperidines; Schizophrenia; Structure-Activity Relationship; Thioridazine; Thioxanthenes; Tranquilizing Agents | 1975 |
Phenothiazine drugs: structure-activity relationships explained by a conformation that mimics dopamine.
Topics: Antipsychotic Agents; Chlorpromazine; Computers; Dopamine; Fluphenazine; Models, Molecular; Molecular Conformation; Perphenazine; Prochlorperazine; Promazine; Structure-Activity Relationship; Thiethylperazine; Trifluoperazine; Triflupromazine | 1975 |
Anodic coulometric detection with a glassy carbon electrode in combination with reversed-phase high-performance liquid chromatography. Determination of blood levels of perphenazine and fluphenazine.
Topics: Carbon; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrodes; Fluphenazine; Glass; Humans; Microchemistry; Oxidation-Reduction; Perphenazine; Solvents | 1976 |
Patterns of symptom change in anxious depressed outpatients treated with different drugs.
Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Depression; Desipramine; Diazepam; Drug Combinations; Fluphenazine; Humans; Imipramine; Mental Disorders; Nortriptyline; Perphenazine; Thioridazine; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1975 |
Drug-induced dystonia.
Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphenazine; Haloperidol; Humans; Male; Mental Disorders; Mesoridazine; Middle Aged; Perphenazine; Psychotic Disorders; Psychotropic Drugs; Schizophrenia; Thioridazine; Thiothixene; Trifluoperazine | 1975 |
Comparative analysis of persistent dyskinesias of long-term usage with neuroleptics in France and in Japan.
Topics: Adult; Chlorpromazine; Female; Fluphenazine; France; Humans; Japan; Male; Middle Aged; Movement Disorders; Perphenazine; Time Factors; Tranquilizing Agents | 1975 |
[Stripping voltammetric determination of perphenazine and some antipsychotic drugs at carbon paste electrodes].
Topics: Antipsychotic Agents; Chlorpromazine; Electrochemistry; Electrodes; Fluphenazine; Humans; Perphenazine; Spectrophotometry, Ultraviolet; Tablets; Trifluoperazine | 1990 |
Comparison of prolactin responses to D-1 and D-2 antagonists in rats: Ro 22-1319 is a potent D-2 antagonist.
Topics: Animals; Antipsychotic Agents; Benzazepines; Domperidone; Fluphenazine; Haloperidol; Isoquinolines; Male; Perphenazine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1989 |
Chemotherapy with neuroleptics. Clinical and pharmacokinetic aspects with a particular view to depot preparations.
Topics: Administration, Oral; Antipsychotic Agents; Clopenthixol; Delayed-Action Preparations; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Flupenthixol; Fluphenazine; Haloperidol; Humans; Kinetics; Long-Term Care; Patient Compliance; Perphenazine; Schizophrenia; Schizophrenic Psychology; Thiazines | 1985 |
Chronic treatment with five different neuroleptics elicits behavioral supersensitivity to opiate infusion into the nucleus accumbens.
Topics: Animals; Antipsychotic Agents; Enkephalin, Methionine; Flupenthixol; Fluphenazine; Haloperidol; Male; Nucleus Accumbens; Perphenazine; Phenothiazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Septal Nuclei; Sulpiride; Time Factors | 1986 |
Flow injection analysis of three N-substituted phenothiazine drugs with amperometric detection at a carbon fibre array electrode.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Fluphenazine; Perphenazine; Tablets; Triflupromazine | 1985 |
The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Chlorpromazine; Chlorprothixene; Clopenthixol; Desipramine; Fluphenazine; Histamine Release; Imipramine; Kinetics; Male; Mast Cells; Methotrimeprazine; Nortriptyline; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Rats; Solvents; Structure-Activity Relationship; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1972 |
Relief of postherpetic neuralgia with psychotropic drugs.
Topics: Aged; Amitriptyline; Analgesics; Antidepressive Agents; Antipsychotic Agents; Female; Fluphenazine; Herpesviridae Infections; Humans; Male; Middle Aged; Neuralgia; Nortriptyline; Pain; Perphenazine; Thioridazine | 1973 |
Antagonistic activity of some phenothiazine derivatives against neurohumoral transmitters.
Topics: Acetylcholine; Animals; Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Female; Fluphenazine; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Neurotransmitter Agents; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rabbits; Rats; Receptors, Adrenergic; Serotonin Antagonists; Thioridazine; Trifluoperazine; Triflupromazine; Trimeprazine | 1973 |
Identification of phenothiazine derivatives and analogs by x-ray diffraction. I. Examination of pure compounds.
Topics: Acepromazine; Chlorpromazine; Evaluation Studies as Topic; Fluphenazine; Fumarates; Maleates; Malonates; Mathematics; Methods; Organophosphorus Compounds; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Sulfoxides; Thioridazine; Trifluoperazine; Triflupromazine; X-Ray Diffraction | 1971 |
Identification of phenothiazine derivatives and analogs by x-ray diffraction. II. Active substances in pharmaceutical formulations.
Topics: Amitriptyline; Chlorprothixene; Crystallization; Dibenzazepines; Fluphenazine; Imipramine; Methods; Methotrimeprazine; Nortriptyline; Opipramol; Perphenazine; Phenothiazines; Picrates; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Thioridazine; Triflupromazine; X-Ray Diffraction | 1971 |
[Depot preparations in psychiatry].
Topics: Antipsychotic Agents; Delayed-Action Preparations; Fluphenazine; Humans; Mental Disorders; Perphenazine | 1974 |
Tissue accumulation of metabolites during chronic administration of piperazine-substituted phenothiazine drugs.
Topics: Amines; Animals; Antipsychotic Agents; Brain; Chromatography, Thin Layer; Dealkylation; Ethylenediamines; Female; Fluphenazine; Humans; Kidney; Liver; Male; Mass Spectrometry; Mental Disorders; Perphenazine; Piperazines; Prochlorperazine; Species Specificity; Sulfoxides; Time Factors; Trifluoperazine | 1974 |
The effect of phenothiazines on botulinus intoxication.
Topics: Animals; Antitoxins; Arachnida; Basal Ganglia Diseases; Botulinum Toxins; Botulism; Butyrophenones; Drug Synergism; Female; Fluphenazine; Haloperidol; Male; Perphenazine; Phenothiazines; Toxins, Biological; Trifluoperazine | 1974 |
Modification of the receptor component of adenylate cyclase in the rat brain by phenothiazine derivatives.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Brain; Brain Chemistry; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Fluphenazine; Haloperidol; Hydroxylation; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Perphenazine; Prochlorperazine; Promazine; Rats; Receptors, Drug; Thiothixene; Tritium | 1974 |
[Sudden cessation of psychotropic drugs].
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Blood Pressure; Chlorpromazine; Electroencephalography; Epinephrine; Female; Fluphenazine; Galvanic Skin Response; Haloperidol; Humans; Imipramine; Male; Middle Aged; Muscle Tonus; Perphenazine; Phenothiazines; Physical Exertion; Schizophrenia; Schizophrenia, Paranoid; Serotonin; Substance Withdrawal Syndrome; Syndrome; Tranquilizing Agents; Trifluoperazine; Trifluperidol | 1974 |
Examination of phenothiazine-albumin interaction by ultraviolet difference spectrophotometry.
Topics: Animals; Antipsychotic Agents; Binding Sites; Cattle; Chlorpromazine; Fluphenazine; Humans; Hydrogen-Ion Concentration; Mathematics; Perphenazine; Phenothiazines; Promazine; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Trifluoperazine; Triflupromazine; Trimeprazine | 1974 |
[Activity of various neuroleptics after single repeated treatment in the mice submitted to the four plate test and the escape test].
Topics: Animals; Chlorpromazine; Chlorprothixene; Diazepam; Drug Evaluation, Preclinical; Electroshock; Escape Reaction; Fluphenazine; Haloperidol; Methotrimeprazine; Mice; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluperidol | 1974 |
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Chlorpromazine; Clozapine; Fluphenazine; Guinea Pigs; Haloperidol; Haplorhini; Humans; In Vitro Techniques; Perphenazine; Phenothiazines; Promazine; Rats; Receptors, Cholinergic; Schizophrenia; Thioridazine; Trifluoperazine; Triflupromazine | 1974 |
Cerebrospinal homovanillic acid and 5-hydroxyindoleacetic acid in huntington's chorea.
Topics: Adult; Chlormethiazole; Chlorpromazine; Female; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Methotrimeprazine; Middle Aged; Motor Activity; Perphenazine; Phenylacetates | 1974 |
Effects of phenothiazines and phenothiazine metabolites on adenyl cyclase and the cyclic AMP response in the rat brain.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Cerebral Cortex; Chlorpromazine; Cyclic AMP; Enzyme Activation; Fluphenazine; Haloperidol; Hydroxylation; Hypothalamus; In Vitro Techniques; Male; Neuroglia; Neurons; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine | 1974 |
Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. II. Structural requirements for D-amino acid oxidase inhibition.
Topics: Animals; Chemical Phenomena; Chemistry; Chlorpromazine; D-Amino-Acid Oxidase; Enzymes; Flavin-Adenine Dinucleotide; Fluphenazine; In Vitro Techniques; Kidney; Kinetics; Perphenazine; Swine; Thioridazine; Trifluoperazine | 1966 |
Inhibition of Na+K+-activated adenosine triphosphatase activity in rat brain by substituted phenothiazines.
Topics: Adenosine Triphosphatases; Aminobutyrates; Animals; Brain; Chlorpromazine; Dextroamphetamine; Fluphenazine; Imipramine; In Vitro Techniques; Microsomes; Pentobarbital; Pentylenetetrazole; Perphenazine; Phenothiazines; Potassium; Prochlorperazine; Promazine; Promethazine; Rats; Sodium; Strychnine; Thiethylperazine; Thioridazine; Trifluoperazine; Triflupromazine | 1966 |
Studies of flavin-adenine dinucleotide-requiring enzymes and phenothiazines. 3. Inhibition kinetics with highly purified D-amino acid oxidase.
Topics: Animals; Chlorpromazine; Chlorprothixene; D-Amino-Acid Oxidase; Fluphenazine; Imipramine; Kinetics; Perphenazine; Phenothiazines; Promazine; Promethazine; Swine; Thioridazine; Trifluoperazine; Triflupromazine; Trimeprazine; Ultracentrifugation | 1967 |
[UV-spectrophotometry in drug control. 7. Effect of substitution and the solvents on the UV-spectrophotometric behavior of drugs with phenothiazine-chromophore].
Topics: Acepromazine; Chlorpromazine; Ethanol; Fluphenazine; Hydrochloric Acid; Methanol; Methotrimeprazine; Parasympatholytics; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Solvents; Spectrophotometry; Thiethylperazine; Thioridazine; Trifluoperazine; Ultraviolet Rays; Water | 1968 |
[Neuroleptic therapy of schizophrenia from pharmacological viewpoint].
Topics: Animals; Apomorphine; Arousal; Caudate Nucleus; Chlorpromazine; Chlorprothixene; Electroencephalography; Fluphenazine; Haloperidol; Humans; Methotrimeprazine; Perphenazine; Phenothiazines; Promazine; Rats; Reflex; Schizophrenia; Thioridazine; Tranquilizing Agents | 1969 |
Effects of some phenothiazines on unilateral ovarian compensatory hypertrophy in the rat.
Topics: Animals; Castration; Chemical Phenomena; Chemistry; Chlorpromazine; Female; Fluphenazine; Hypertrophy; Hypothalamo-Hypophyseal System; Methotrimeprazine; Organ Size; Ovarian Diseases; Perphenazine; Phenothiazines; Pituitary Gland; Prochlorperazine; Promazine; Rats; Thioridazine; Trifluoperazine; Trimeprazine | 1969 |
In vivo piperazine ring degradation in neuroleptic and antihistaminic drugs.
Topics: Animals; Biotransformation; Dogs; Ethylenediamines; Female; Fluphenazine; Histamine H1 Antagonists; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Rats; Rats, Inbred Strains; Tranquilizing Agents; Trifluoperazine | 1972 |
Effects of tricyclic compounds on the histamine response of isolated atria.
Topics: Amitriptyline; Animals; Antidepressive Agents; Chlorpromazine; Dose-Response Relationship, Drug; Female; Fluphenazine; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Imipramine; In Vitro Techniques; Male; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Rabbits; Thioridazine; Time Factors; Triflupromazine | 1974 |
Tissue metabolites of trifluoperazine, fluphenazine, prochlorperazine, and perphenazine in the rat: indentification and synthesis.
Topics: Animals; Biodegradation, Environmental; Biotransformation; Chromatography, Thin Layer; Fluphenazine; Kidney; Liver; Lung; Male; Mass Spectrometry; Perphenazine; Prochlorperazine; Rats; Trifluoperazine | 1974 |
Pharmacological vs. clinical physiognomy of neuroleptics, with special reference to their sedative and antipsychotic effects.
Topics: Animals; Behavior, Animal; Chlorpromazine; Chlorprothixene; Clopenthixol; Dogs; Drug Evaluation, Preclinical; Drug Tolerance; Flupenthixol; Fluphenazine; Haloperidol; Mice; Motor Activity; Perphenazine; Rats; Tranquilizing Agents | 1974 |
General clinical aspects of depot neuroleptics and some experiences with depot neuroleptics.
Topics: Delayed-Action Preparations; Drug Combinations; Drug Therapy, Combination; Esters; Fatty Acids; Fluphenazine; Humans; Medication Errors; Perphenazine; Pharmaceutical Vehicles; Tranquilizing Agents | 1973 |
Determination of perphenazine and fluphenazine in whole blood by gas chromatography.
Topics: Chromatography, Gas; Fluphenazine; Humans; Methods; Perphenazine; Time Factors | 1973 |
The comparative pharmacology of flupenthixol and some reference neuroleptics.
Topics: Animals; Avoidance Learning; Behavior, Animal; Body Temperature; Cats; Chlorpromazine; Chlorprothixene; Clopenthixol; Conditioning, Operant; Dogs; Drug Evaluation, Preclinical; Ethanol; Female; Fluphenazine; Guinea Pigs; Haloperidol; Isomerism; Male; Mice; Nictitating Membrane; Norepinephrine; Perphenazine; Piperazines; Rabbits; Rats; Structure-Activity Relationship; Tranquilizing Agents | 1973 |
Metabolism of trifluoperazine, fluphenazine, prochlorperazine and perphenazine in rats: in vitro and urinary metabolites.
Topics: Animals; Chromatography, Thin Layer; Dealkylation; Fluphenazine; Hydroxylation; Male; Microsomes, Liver; Oxidation-Reduction; Oxides; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Rats; Spectrophotometry, Ultraviolet; Sulfoxides; Trifluoperazine | 1974 |
Formation of identical metabolites from piperazine- and dimethylamino-substituted phenothiazine drugs in man, rat and dog.
Topics: Animals; Biotransformation; Chlorpromazine; Chromatography, Thin Layer; Dimethylamines; Dogs; Female; Fluphenazine; Humans; Male; Mass Spectrometry; Methylation; Perphenazine; Phenothiazines; Piperazines; Prochlorperazine; Promazine; Propylamines; Rats; Sulfoxides; Trifluoperazine; Triflupromazine | 1974 |
Detection of some psychotherapeutic drugs and their metabolites in urine.
Topics: Amitriptyline; Amphetamine; Analgesics; Antidepressive Agents; Chlordiazepoxide; Chlorpromazine; Chromatography, Thin Layer; Desipramine; Diazepam; Fluphenazine; Haloperidol; Humans; Imipramine; Indicators and Reagents; Methadone; Perphenazine; Solvents; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1971 |
[Follow-up studies of schizophrenia].
Topics: Adult; Catalepsy; Catatonia; Chlorpromazine; Chronic Disease; Convulsive Therapy; Depersonalization; Depression; Electroconvulsive Therapy; Female; Fluphenazine; Follow-Up Studies; Humans; Illusions; Male; Methotrimeprazine; Middle Aged; Perphenazine; Schizophrenia | 1971 |
Competition of phenothiazines with oestradiol for oestradiol receptors in rat brain.
Topics: Animals; Binding Sites; Carbon Isotopes; Cerebral Cortex; Estradiol; Female; Fluphenazine; Hypothalamus; Perphenazine; Phenothiazines; Pituitary Gland; Rats; Receptors, Drug; Tritium | 1971 |
Induced formation of phenylalanine ammonia lyase and pisatin by chlorpromazine and other phenothiazine derivatives.
Topics: Carbon Isotopes; Chlorpromazine; Cycloheximide; Deamination; Enzyme Induction; Fluphenazine; Lectins; Leucine; Lyases; Perphenazine; Phenothiazines; Phenylalanine; Plant Lectins; Plant Proteins; Plants, Edible; Prochlorperazine; Promazine; Promethazine; Purines; RNA; Stimulation, Chemical; Structure-Activity Relationship; Thioridazine; Trifluoperazine; Triflupromazine | 1971 |
Physical properties of quaternary ammonium salts of phenothiazine derivatives.
Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Fluphenazine; Infrared Rays; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Quaternary Ammonium Compounds; Spectrum Analysis; Triflupromazine; Ultraviolet Rays | 1971 |
[Role of halogens in the molecule of some neurleptics which prolong the survival of mice poisoned by botulinum toxin "A"].
Topics: Animals; Antidotes; Botulinum Toxins; Botulism; Female; Fluphenazine; Halogens; Male; Mice; Perphenazine; Time Factors | 1970 |
[On the mode of action and the question of central organic late damages of continuous neuroleptic treatment].
Topics: Aged; Brain Stem; Butyrophenones; Central Nervous System; Cerebral Ventriculography; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease, Secondary; Perphenazine; Personality; Tranquilizing Agents | 1966 |
Effects of certain psychotropic drugs on immunologic pregnancy tests.
Topics: Chlorpromazine; Chlorprothixene; Chorionic Gonadotropin; False Positive Reactions; Female; Fluphenazine; Humans; Pentylenetetrazole; Perphenazine; Pharmacology; Phenothiazines; Pregnancy; Pregnancy Tests; Thioridazine; Trifluoperazine; Xanthenes | 1969 |
The influence of various neuroleptic drugs on shock avoidance responding in rats. I. Nondiscriminated Sidman avoidance procedure.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Benzimidazoles; Butyrophenones; Chlorpromazine; Depression, Chemical; Electroshock; Escape Reaction; Female; Fluorine; Fluphenazine; Haloperidol; Isonipecotic Acids; Perphenazine; Piperidines; Promazine; Rats; Spiro Compounds; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1969 |
Analysis of certain phenothiazines and their dosage forms by photometric titration with ceric sulfate.
Topics: Chlorpromazine; Colorimetry; Dosage Forms; Fluphenazine; Methods; Perphenazine; Pharmacopoeias as Topic; Phenothiazines; Photometry; Prochlorperazine; Solutions; Spectrophotometry; Tablets; Trifluoperazine; Trimeprazine; Ultraviolet Rays | 1969 |
[Current problems of endogenous depression].
Topics: Amitriptyline; Antidepressive Agents; Chlorpromazine; Convulsive Therapy; Depression; Desipramine; Fluphenazine; Humans; Imipramine; Methotrimeprazine; Nortriptyline; Perphenazine; Thioridazine | 1970 |
Use of antipsychotic and antidepressant drugs by chronically ill patients.
Topics: Ambulatory Care; Antidepressive Agents; Chlorpromazine; Chlorprothixene; Drug Utilization; Fluphenazine; Humans; Imipramine; Mental Disorders; Perphenazine; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1970 |
Sudden death in phenothiazine therapy. (A clinicopathologic study of 12 cases).
Topics: Adolescent; Adult; Aged; Asphyxia; Autopsy; Brain; Brain Diseases; Chlorpromazine; Death, Sudden; Drug Synergism; Electrocardiography; Female; Fluphenazine; Heart Diseases; Humans; Kidney; Liver; Lung; Male; Mental Disorders; Middle Aged; Myocardium; Perphenazine; Phenothiazines; Prochlorperazine; Schizophrenia; Spleen; Thioridazine; Tranquilizing Agents; Triflupromazine | 1970 |
The influence of various neuroleptic drugs on noise escape response in rats.
Topics: Animals; Antidepressive Agents; Avoidance Learning; Benperidol; Blepharoptosis; Butyrophenones; Catalepsy; Chlorpromazine; Escape Reaction; Female; Fluorine; Fluphenazine; Haloperidol; Humans; Noise; Perphenazine; Piperidines; Rats; Spiro Compounds; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine | 1970 |
Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and
Topics: Acepromazine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benperidol; Chlorpromazine; Chlorprothixene; Fluphenazine; Haloperidol; Male; Mastication; Methods; Motor Activity; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rats; Thiazines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine | 1967 |
Comparison of perphenazine and fluphenazine enanthates in rats.
Topics: Analysis of Variance; Animals; Avoidance Learning; Conditioning, Psychological; Depression, Chemical; Fatty Acids; Fluphenazine; Locomotion; Male; Perphenazine; Rats; Time Factors | 1968 |
Single daily doses of neuroleptic drugs.
Topics: Chlorpromazine; Chlorprothixene; Chronic Disease; Dosage Forms; Fluphenazine; Haloperidol; Humans; Mental Disorders; Perphenazine; Piperazines; Schizophrenia; Tranquilizing Agents; Trifluoperazine | 1969 |
[Demonstration of some phenothiazine derivatives by thin-layer chromatography on silica gel].
Topics: Chlorpromazine; Chromatography, Thin Layer; Fluphenazine; Methotrimeprazine; Perphenazine; Phenothiazines; Prochlorperazine; Promethazine; Thioridazine | 1965 |
The use of lithium in the affective psychoses.
Topics: Adult; Aged; Bipolar Disorder; Chlorpromazine; Female; Fluphenazine; Humans; Lithium; Male; Middle Aged; Perphenazine; Statistics as Topic | 1966 |
Incidence of late "melanosis" side effects in chronic mental patients after long term phenothiazine therapy.
Topics: Chlorpromazine; Eye Diseases; Fluphenazine; Humans; Male; Melanosis; Penicillamine; Perphenazine; Thioridazine; Trifluoperazine | 1966 |
Conversion of phenothiazine derivatives to the corresponding sulphoxides on thin-layer plates.
Topics: Chemical Phenomena; Chemistry; Chlorpromazine; Chromatography, Gas; Chromatography, Thin Layer; Fluphenazine; Hydrogen Peroxide; Methotrimeprazine; Perphenazine; Phenothiazines; Promazine; Promethazine; Sulfoxides; Thioridazine; Trifluoperazine; Triflupromazine; Ultraviolet Rays | 1966 |
Phenothiazine tranquilizer reversal of amphetamine toxicity for aggregated mice.
Topics: Amphetamine; Animals; Antidotes; Chlorpromazine; Fluphenazine; Mice; Perphenazine; Promazine; Stress, Physiological | 1966 |
[Accidental poisoning caused by phenothiazines in childhood. (Considerations presentation of 9 cases)].
Topics: Child; Child, Preschool; Female; Fluphenazine; Humans; Infant; Male; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Promethazine | 1966 |
Considerations for the pre-clinical evaluation of new psychiatric drugs: a case study with phenothiazine-like tranquilizers.
Topics: Aggression; Animals; Ataxia; Behavior, Animal; Catalepsy; Emotions; Extrapyramidal Tracts; Fear; Fluphenazine; Grooming; Heart Rate; Humans; Hypnotics and Sedatives; Locomotion; Motor Activity; Movement Disorders; Nictitating Membrane; Perphenazine; Phenothiazines; Posture; Psychopharmacology; Pupil; Respiration; Spatial Behavior; Tranquilizing Agents; Vocalization, Animal; Wakefulness | 1966 |
[Arousal inhibiting and catalepsy in neuroleptic drugs].
Topics: Animals; Arousal; Catalepsy; Chlorpromazine; Chlorprothixene; Fluphenazine; Haloperidol; Humans; Methotrimeprazine; Perphenazine; Rats; Tranquilizing Agents | 1966 |
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasympatholytics; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1967 |
Side-effects of phenothiazines.
Topics: Adult; Female; Fluphenazine; Humans; Male; Movement Disorders; Perphenazine; Pregnancy; Trifluoperazine | 1967 |
Differential effects of neuroleptic agents on the pituitary-gonadal axis in men.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Fluphenazine; Haloperidol; Humans; Luteinizing Hormone; Male; Middle Aged; Perphenazine; Prolactin; Testosterone; Thioridazine; Trifluoperazine | 1981 |
Low serum neuroleptic levels predict relapse in schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Perphenazine; Recurrence; Schizophrenia; Schizophrenic Psychology; Thioridazine; Trifluoperazine | 1982 |
[Various aspects of current treatment of patients with alcoholic delirium].
Topics: Adult; Alcoholism; Amitriptyline; Disulfiram; Fluphenazine; Humans; Male; Methotrimeprazine; Middle Aged; Perphenazine; Placebos; Psychotropic Drugs; Suggestion; Trifluoperazine | 1983 |
Phenotypes of dnaA mutants of Escherichia coli sensitive to phenothiazine derivatives.
Topics: Bacterial Proteins; Bacteriophage P1; DNA-Binding Proteins; Escherichia coli; Fluphenazine; Genetic Complementation Test; Microbial Sensitivity Tests; Mutation; Perphenazine; Phenothiazines; Phenotype; Plasmids; Transduction, Genetic; Transformation, Bacterial | 1996 |
Phototoxic properties of neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Clopenthixol; Dermatitis, Phototoxic; Drug Eruptions; Erythrocytes; Flupenthixol; Fluphenazine; Hemolysis; Humans; Methotrimeprazine; Perazine; Perphenazine; Phenothiazines; Promazine; Promethazine; Radiation Dosage; Thiazines; Thioridazine; Thiothixene; Trifluoperazine; Triflupromazine; Ultraviolet Rays | 1997 |
Photosensitization of DNA strand breaks by three phenothiazine derivatives.
Topics: Animals; Base Sequence; DNA; DNA Damage; Fluphenazine; Lasers; Light; Molecular Sequence Data; Perphenazine; Phenothiazines; Photochemistry; Photosensitizing Agents; Salmon; Thermodynamics; Thioridazine; Ultraviolet Rays | 2003 |
Potentiation of thiopentone anaesthesia. Comparison of promethazine, chlorpromazine, perphenazine, fluphenazine, thiopropazate, pipamazine and triflupromazine.
Topics: Aged; Analgesia; Anesthesia; Anesthesia and Analgesia; Antiemetics; Chlorpromazine; Fluphenazine; Histamine H1 Antagonists; Humans; Pain Management; Perphenazine; Phenothiazines; Promethazine; Thiopental; Tranquilizing Agents; Triflupromazine | 1960 |
The antisialogogue effect of phenothiazine derivatives: comparison of pecazine, perphenazine, fluphenazine, thiopropazate, pipamazine and triflupromazine.
Topics: Antiemetics; Fluphenazine; Perphenazine; Phenothiazines; Salivary Glands; Tranquilizing Agents; Triflupromazine | 1960 |
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundice; New Zealand; Perphenazine; Phenothiazines; Poisoning; Pregnancy; Pregnancy Complications; Prochlorperazine; Promazine; Thioridazine; Toxicology; Trifluoperazine; Triflupromazine; Trimeprazine | 1963 |
ALTERATIONS IN RESPONSE TO SOMATIC PAIN ASSOCIATED WITH ANAESTHESIA. XV. FURTHER STUDIES WITH PHENOTHIAZINE DERIVATIVES AND SIMILAR DRUGS.
Topics: Analgesics; Analgesics, Non-Narcotic; Anesthesia; Antiemetics; Antipyretics; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Nociceptive Pain; Pain; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Trifluoperazine; Triflupromazine; Trimeprazine | 1963 |
PHENOTHIAZINE DERIVATIVES.
Topics: Chlorpromazine; Fluphenazine; Perphenazine; Pharmacology; Phenothiazines; Prochlorperazine; Promazine; Toxicology; Trifluoperazine; Triflupromazine | 1964 |
PHENOTHIAZINES IN THE TREATMENT OF NEWLY ADMITTED STATE HOSPITAL PATIENTS: GLOBAL COMPARISON OF EIGHT COMPOUNDS IN TERMS OF AN OUTCOME INDEX.
Topics: Biomedical Research; Chlorpromazine; Drug Therapy; Fluphenazine; Hospitals, State; Humans; Mental Disorders; Perphenazine; Phenothiazines; Prochlorperazine; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine | 1964 |
[ACUTE POISONINGS BY PSYCHOPHARMACOLOGICAL AGENTS IN CHILDHOOD].
Topics: Amphetamine; Aspirin; Child; Chlordiazepoxide; Chlorothiazide; Chlorpromazine; Chlorprothixene; Fluphenazine; Hydantoins; Infant; Perphenazine; Phenmetrazine; Phenobarbital; Reserpine; Toxicology; Triflupromazine | 1964 |
[CLINICAL EXPERIENCES WITH A NEW ANTIPARKINSON AGENT, AKINETON, WITH SPECIAL REFERENCE TO EXTRAPYRAMIDAL SYMPTOMS CAUSED BY PHENOTHIAZINE DERIVATIVES].
Topics: Adolescent; Antiparkinson Agents; Biperiden; Central Nervous System Diseases; Child; Chlorpromazine; Extrapyramidal Tracts; Fluphenazine; Methotrimeprazine; Parasympatholytics; Perphenazine; Phenothiazines; Schizophrenia; Toxicology | 1964 |
[ON THE USE OF PERPHENAZINE (TRILIFAN) AND FLUPHENAZINE (SEVINOL) IN PAINFUL PSYCHOSOMATIC RHEUMATISM-LIKE MANIFESTATIONS WITH PSYCHONEUROTIC BASIS].
Topics: Adolescent; Anxiety; Anxiety Disorders; Back Pain; Drug Therapy; Fluphenazine; Geriatrics; Neurotic Disorders; Pain; Perphenazine; Psychosomatic Medicine; Rheumatic Diseases | 1964 |
PHENOTHIAZINE REDUCTION AS A CAUSE OF REHOSPITALIZATION.
Topics: Chlorpromazine; Drug Therapy; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; Prochlorperazine; Prognosis; Promazine; Schizophrenia; Statistics as Topic; Substance Withdrawal Syndrome; Thioridazine; Tranquilizing Agents; Trifluoperazine | 1965 |
STUDIES OF DRUGS GIVEN BEFORE ANAESTHESIA. VI. THE PHENOTHIAZINE DERIVATIVES.
Topics: Anesthesia; Anesthesia, General; Atropine; Chlorpromazine; Chlorprothixene; Fluphenazine; Humans; Meperidine; Methohexital; Methotrimeprazine; Nitrous Oxide; Oxygen; Perphenazine; Pharmacology; Phenothiazines; Preanesthetic Medication; Prochlorperazine; Promazine; Promethazine; Thiazines; Thiethylperazine; Toxicology; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine | 1965 |
Disturbed glucose metabolism among patients taking olanzapine and typical antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Cohort Studies; Depressive Disorder; Diabetes Mellitus; Female; Fluphenazine; Glucose; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Perphenazine; Retrospective Studies | 2003 |
Mitochondria and plasma membrane as targets of UVA-induced toxicity of neuroleptic drugs fluphenazine, perphenazine and thioridazine.
Topics: 3T3 Cells; Animals; Antipsychotic Agents; Cell Membrane; Fluphenazine; Mice; Mitochondria; Perphenazine; Thioridazine; Ultraviolet Rays | 2005 |
In vitro phototoxicity of phenothiazines: involvement of stable UVA photolysis products formed in aqueous medium.
Topics: Animals; Antipsychotic Agents; BALB 3T3 Cells; Cell Proliferation; Cell Survival; Erythrocytes; Fluphenazine; Hemolysis; In Vitro Techniques; Mice; Perphenazine; Phenothiazines; Photolysis; Solutions; Thioridazine; Ultraviolet Rays | 2006 |
Chemiluminescence sensor for the determination of perphenazine based on a molecular imprinted polymer.
Topics: Fluphenazine; Humans; Luminescent Measurements; Molecular Structure; Perphenazine; Polymers; Reference Values; Sensitivity and Specificity; Time Factors | 2006 |
Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration population.
Topics: Antipsychotic Agents; Benzodiazepines; Blood Glucose; Chlorpromazine; Cohort Studies; Female; Fluphenazine; Haloperidol; Hospitals, Veterans; Humans; Hyperglycemia; Incidence; Male; Middle Aged; Olanzapine; Perphenazine; Retrospective Studies; Risk Assessment; Risk Factors; Risperidone; Southeastern United States; Time Factors; Veterans | 2007 |
Attentional and emotional functioning in schizophrenia patients treated with conventional and atypical antipsychotic drugs.
Topics: Adult; Amisulpride; Analysis of Variance; Antipsychotic Agents; Attention; Benzodiazepines; Dibenzothiazepines; Emotions; Fluphenazine; Haloperidol; Humans; Memory; Middle Aged; Olanzapine; Perazine; Perphenazine; Quetiapine Fumarate; Recognition, Psychology; Risperidone; Schizophrenia; Sulpiride | 2012 |
Perphenazine suspension: a new, old treatment, side effects and continuous use.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cholinergic Antagonists; Clinical Trials as Topic; Drug Compounding; Drug Delivery Systems; Female; Fluphenazine; Haloperidol; Hospitals, Psychiatric; Humans; Male; Movement Disorders; Olanzapine; Patient Discharge; Perphenazine; Risperidone; Suspensions; Treatment Outcome | 2012 |
Simultaneous UPLC-MS/MS assay for the detection of the traditional antipsychotics haloperidol, fluphenazine, perphenazine, and thiothixene in serum and plasma.
Topics: Antipsychotic Agents; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Fluphenazine; Haloperidol; Humans; Perphenazine; Reproducibility of Results; Tandem Mass Spectrometry; Thiothixene; Time Factors | 2013 |
Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2'-bipyridyl) ruthenium (II) electrochemiluminescence detection.
Topics: Electrochemical Techniques; Electrophoresis, Capillary; Fluphenazine; Luminescent Measurements; Molecular Structure; Organometallic Compounds; Perphenazine | 2014 |
Quantitation of Haloperidol, Fluphenazine, Perphenazine, and Thiothixene in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS).
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Drug Monitoring; Fluphenazine; Haloperidol; Humans; Perphenazine; Tandem Mass Spectrometry; Thiothixene | 2016 |
Modulating cancer cell survival by targeting intracellular cholesterol transport.
Topics: Administration, Intravenous; Administration, Oral; Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Autophagy; bcl-2-Associated X Protein; Biological Transport; Cell Survival; Cholesterol; Desipramine; Endocytosis; Endosomes; Female; Flupenthixol; Fluphenazine; Gene Expression Regulation; Gene Knockdown Techniques; HCT116 Cells; Homeostasis; Humans; Inhibitory Concentration 50; Liposomes; Lysosomes; MCF-7 Cells; Melanoma; Mice; Nortriptyline; Perphenazine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sphingomyelin Phosphodiesterase; STAT3 Transcription Factor | 2017 |
FLUPHENAZINE AND PERPHENAZINE IMPACT ON MELANOGENESIS AND ANTIOXIDANT ENZYMES ACTIVITY IN NORMAL HUMAN MELANOCYTES.
Topics: Catalase; Cells, Cultured; Fluphenazine; Humans; Melanins; Melanocytes; Oxidative Stress; Perphenazine; Superoxide Dismutase | 2016 |
Simultaneous spectrophotometric determination of fluphenazine HCl and nortriptyline HCl in presence of their potential impurities perphenazine and dibenzosuberone in bulk and pharmaceutical formulation.
Topics: Dibenzocycloheptenes; Drug Compounding; Fluphenazine; Nortriptyline; Perphenazine; Spectrophotometry | 2022 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |