fluphenazine and loxapine

fluphenazine has been researched along with loxapine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19907 (43.75)18.7374
1990's1 (6.25)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Strassburg, CP; Tukey, RH1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Andaluz, B; Buschmann, H; Codony, X; Cubí, R; Díaz, JL; Dordal, A; Guitart, X; Hernández, E; Hernández, S; Holenz, J; Mas, J; Mercè, R; Monroy, X; Pérez, R; Romero, G; Sánchez, E; Sanfeliu, O; Torrens, A1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bennis, K; Ducki, S; Lesage, F; Vivier, D1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Clement-Cormier, YC; Robison, GA1
Doss, FW1
Davis, JM1
Blue, MG; Fraley, DS; Noro, S; Schneider, SM1
Davis, KL; Kendler, KS1
Athanassenas, G; Frangos, E; Gabriel, J; Hoïdas, S; Kourkoubas, A; Papadopoulos, E; Tsitourides, S1
Eichelman, BS; Hutchins, LG; Kornguth, ML1

Reviews

3 review(s) available for fluphenazine and loxapine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for fluphenazine and loxapine

ArticleYear
Recent developments in the drug treatment of schizophrenia.
    The American journal of psychiatry, 1976, Volume: 133, Issue:2

    Topics: Chlorpromazine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Resistance; Fluphenazine; Humans; Loxapine; Molindone; Phenothiazines; Placebos; Promazine; Research Design; Schizophrenia; Structure-Activity Relationship; Tranquilizing Agents; Trifluoperazine

1976
Serum calcium and magnesium levels in chronic schizophrenics.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:4

    Topics: Calcium; Chronic Disease; Dyskinesia, Drug-Induced; Female; Fluphenazine; Humans; Loxapine; Magnesium; Male; Middle Aged; Pimozide; Schizophrenia

1983

Other Studies

11 other study(ies) available for fluphenazine and loxapine

ArticleYear
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Adenylyl Cyclases; Benzoxazines; Cell Line; Humans; Indoles; Ligands; Piperidines; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sulfonamides

2005
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
Adenylate cyclase from various dopaminergic areas of the brain and the action of antipsychotic drugs.
    Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18

    Topics: Adenylyl Cyclases; Amygdala; Animals; Antipsychotic Agents; Apomorphine; Brain; Caudate Nucleus; Clozapine; Dopamine; Fluphenazine; Isoproterenol; Loxapine; Median Eminence; Norepinephrine; Olfactory Bulb; Rats

1977
The effect of antipsychotic drugs on body weight: a retrospective review.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:12

    Topics: Antipsychotic Agents; Body Weight; Fluphenazine; Haloperidol; Humans; Loxapine; Schizophrenia; Thioridazine; Thiothixene

1979
Successful treatment of neuroleptic malignant syndrome with sodium nitroprusside.
    Annals of internal medicine, 1986, Volume: 104, Issue:1

    Topics: Combined Modality Therapy; Female; Ferricyanides; Fluphenazine; Humans; Loxapine; Middle Aged; Neuroleptic Malignant Syndrome; Nitroprusside; Vasoconstriction

1986
Acute and chronic effects of neuroleptic drugs on plasma and brain homovanillic acid in the rat.
    Psychiatry research, 1984, Volume: 13, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Homovanillic Acid; Loxapine; Male; Metoclopramide; Molindone; Phenylacetates; Rats; Rats, Inbred Strains; Sulpiride

1984
Binding of psychotropic drugs to isolated alpha-acid glycoprotein.
    Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17

    Topics: Binding, Competitive; Chlorpromazine; Fluphenazine; Humans; Imipramine; Kinetics; Loxapine; Molindone; Orosomucoid; Protein Binding; Psychotropic Drugs; Thioridazine; Thiothixene; Trihexyphenidyl

1981