fluphenazine and clozapine

fluphenazine has been researched along with clozapine in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199024 (26.09)18.7374
1990's32 (34.78)18.2507
2000's24 (26.09)29.6817
2010's10 (10.87)24.3611
2020's2 (2.17)2.80

Authors

AuthorsStudies
Ellefson, CR; Kehr, JR; Miller, A; Woo, CM1
Krapcho, J; Michel, IM; Turk, CF; Weinryb, I1
George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH1
Butler, DE; Coughenour, LL; DeWald, HA; Downs, DA; Heffner, TG; Lustgarten, D; Pugsley, TA; Wise, LD1
Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A1
Strassburg, CP; Tukey, RH1
Ernsberger, P; Hufeisen, SJ; Jayathilake, K; Kroeze, WK; Meltzer, HY; Popadak, BA; Renock, SM; Roth, BL; Steinberg, S1
Andaluz, B; Buschmann, H; Codony, X; Cubí, R; Díaz, JL; Dordal, A; Guitart, X; Hernández, E; Hernández, S; Holenz, J; Mas, J; Mercè, R; Monroy, X; Pérez, R; Romero, G; Sánchez, E; Sanfeliu, O; Torrens, A1
Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Kottke, T; Ligneau, X; Stark, H; von Coburg, Y; Weizel, L1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Modestin, J; Petrin, A1
Gründig, E; Weiss, J1
Bowers, MB; Rozitis, A2
Clement-Cormier, YC; Robison, GA1
Munday, KA; Poat, JA; Sumners, C; Woodruff, GN1
Kudrin, VS; Mineyeva, MF; Rayevsky, KS1
Bloss, JL; Singer, GH1
Costall, B; Naylor, RJ2
Ahn, HS; Demirjian, C; Makman, MH; Mishra, RK1
Gutierrez, R; Konicki, E; Litman, RE; Owen, RR; Pickar, D; Rapaport, MH1
Pickar, D1
Kirch, DG; McAllister, CG; Pickar, D; Rapaport, MH1
Ellison, G; See, RE1
Salama, AI; Saller, CF1
Cohen, BM; Lipinski, JF1
Choras, PT; Cole, JO; Fulwiler, CE; Pope, HG1
Auer, B; Barnas, C; Fleischhacker, W; Haring, C; Hinterhuber, H; Humpel, C; Saria, A1
Greenberg, D; Snyder, SH; Yamumura, HI1
Schechter, MD1
Aranovich, AG; Gamburg, AL; Kotel'kevich, IuN; Omorokov, BM; Rasniuk, VA1
Borison, RL; Diamond, BI1
Friedman, E; Gianutsos, G; Kuster, J1
Faustman, WO; Fowler, SC1
Arnt, J1
Hsiao, JK; Litman, RE; Owen, RR; Pickar, D; Su, TP1
Bechter, K1
Cawley, TA; Luthin, GR; Ruggieri, MR; Shickley, TJ1
Opler, LA; Yovell, Y1
Haier, RJ; Pickar, D; Zahn, TP1
Clem, T; Hommer, DW; Litman, RE; Pickar, D; Radant, A1
Chen, JF; Weiss, B1
Dorevitch, A; Durst, R; Fraenkel, Y1
Hong, WW; Hsiao, JK; Litman, RE; Pickar, D; Potter, WZ; Su, TP; Weissman, EM1
Benkelfat, C; Gutierrez-Esteinou, R; Hadd, K; Hsiao, J; Lawlor, BA; Murphy, DL; Owen, RR; Pickar, D1
Fiorella, D; Rabin, RA; Winter, JC1
Hong, WW; Litman, RE; Pickar, D; Potter, WZ; Su, TP1
Bauer, U; Gallhofer, B; Gruppe, H; Krieger, S; Lis, S1
Fukamauchi, F; Kito, S; Mataga, N; Miyoshi, R; Sakai, M; Semba, J1
Andreason, P; Cohen, RM; Litman, RE; Nordahl, TE; Pickar, D; Semple, WE1
Bunker, MT; Marken, PA; Ruehter, VL; Schneiderhan, ME1
Braghiroli, L; Cheng, CY; De Feo, G; Fiani, M; Mazzanti, G; Ponzianelli, A1
Baldessarini, RJ; Kula, NS; Neumeyer, JL; Tarazi, FI; Yeghiayan, SK1
Breier, A; Elman, I; Goldstein, DS1
Oreland, L; Prince, JA; Yassin, MS1
Baumgartner, R; Gönner, F; Merlo, MC; Schüpbach, D1
Buljat, G; Dodig, G; Jelovac, N; Marovic, A; Miklic, P; Mise, S; Perovic, D; Petek, M; Prkacin, I; Rucman, R; Seiwerth, S; Sikiric, P; Turkovic, B1
Cohen, RM; Nordahl, TE; Pickar, D; Semple, WE1
Braghiroli, L; Mazzanti, G; Ponzianelli, A1
Bradley, RJ; Dwyer, DS; Liu, Y1
Jakovljevic, M; Mihaljević-Peles, A; Mrsic, M; Sagud, M1
Miledi, R; Nguyen, QT; Yang, J1
Marder, SR; Pierre, JM; Saunders, CS; Wirshing, DA; Wirshing, WC1
Bilici, M; Cakirbay, H; Guler, M; Tan, U; Tosun, M; Ulgen, M1
DeQuardo, J; Gilani, S; Rajarethinam, R; Tancer, M1
Miller, DD1
Conley, RR; Kelly, DL; Love, RC; McMahon, RP1
Alvir, JM; Kane, JM; Lieberman, JA; Robinson, DG; Sheitman, BB; Woerner, MG1
Barna, I; Gazdag, G; Iványi, Z; Tolna, J1
Dwyer, DS; Lu, XH1
Baldessarini, RJ; Gan, L; Moran-Gates, T; Park, YS; Tarazi, FI; Zhang, K1
Aukst-Margetić, B; Badanjak, A; Margetić, B1
Aukst Margetić, B; Margetić, B1
Duggal, HS1
Britvić, D; Ille, T; Stanković, Z; Vuković, O1
Aamodt, EJ; Donohoe, DR; Dwyer, DS; Phan, T; Weeks, K1
Mihaljević-Peles, A; Mihanović, M; Sagud, M; Silić, A; Zivković, M1
Goodwin, DG; Lindsay, DS; Strobl, JS1
de Jong, MH; Van Gool, AR; Zemel, D1
Gibson, LE; Green, AI; Mesholam-Gately, RI; Seidman, LJ1
Birky, T; Che, P; Cottingham, C; Jiao, K; Percival, S; Wang, H; Wang, Q; Wang, RX; Zhang, W; Zhou, L1
Bhattiprolu, AK; Brzustowicz, LM; Clarke, SG; Crosta, CM; Dudzinski, NR; Firestein, BL; Fu, AY; Hernandez, K; Moore, JC; Paradiso, KG1
Osman, E; Yıldız, M1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Reviews

3 review(s) available for fluphenazine and clozapine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants].
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1

    Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dibenzazepines; Dose-Response Relationship, Drug; Fluphenazine; Humans; Imipramine; Nortriptyline; Perazine; Phenelzine; Thioridazine

1976

Trials

10 trial(s) available for fluphenazine and clozapine

ArticleYear
Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine.
    Archives of general psychiatry, 1992, Volume: 49, Issue:5

    Topics: Adult; Antipsychotic Agents; Clozapine; Dopamine; Double-Blind Method; Female; Fluphenazine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Placebos; Schizophrenia; Schizophrenic Psychology; Serotonin

1992
Predictors of clozapine response in schizophrenia.
    The Journal of clinical psychiatry, 1994, Volume: 55 Suppl B

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Double-Blind Method; Female; Fluphenazine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probability; Receptors, Neurotransmitter; Schizophrenia; Treatment Outcome

1994
Effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia.
    Schizophrenia research, 1994, Volume: 13, Issue:2

    Topics: Adult; Attention; Auditory Perception; Clozapine; Dominance, Cerebral; Dyskinesia, Drug-Induced; Female; Fluphenazine; Hallucinations; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Reaction Time; Schizophrenia; Schizophrenic Psychology; Visual Perception

1994
Quantitative effects of typical and atypical neuroleptics on smooth pursuit eye tracking in schizophrenia.
    Schizophrenia research, 1994, Volume: 12, Issue:2

    Topics: Adult; Attention; Clozapine; Double-Blind Method; Female; Fluphenazine; Humans; Male; Psychiatric Status Rating Scales; Pursuit, Smooth; Saccades; Schizophrenia; Schizophrenic Psychology

1994
Clinical response to clozapine in patients with schizophrenia.
    Archives of general psychiatry, 1994, Volume: 51, Issue:2

    Topics: Clozapine; Dioxanes; Double-Blind Method; Drug Therapy, Combination; Fluphenazine; Hospitalization; Humans; Idazoxan; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1994
Effects of clozapine and fluphenazine treatment on responses to m-chlorophenylpiperazine infusions in schizophrenia.
    Archives of general psychiatry, 1993, Volume: 50, Issue:8

    Topics: Adult; Body Temperature; Clozapine; Female; Fluphenazine; Hospitalization; Humans; Hydrocortisone; Infusions, Intravenous; Male; Piperazines; Placebos; Prolactin; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Serotonin; Stimulation, Chemical

1993
Idazoxan and response to typical neuroleptics in treatment-resistant schizophrenia. Comparison with the atypical neuroleptic, clozapine.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 168, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Clozapine; Dioxanes; Double-Blind Method; Drug Therapy, Combination; Female; Fluphenazine; Humans; Idazoxan; Imidazoles; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1996
The brain metabolic patterns of clozapine- and fluphenazine-treated female patients with schizophrenia: evidence of a sex effect.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:5

    Topics: Adult; Animals; Antipsychotic Agents; Cerebral Cortex; Clozapine; Female; Fluphenazine; Humans; Limbic System; Male; Multivariate Analysis; Neostriatum; Schizophrenia; Sex Factors; Tomography, Emission-Computed

1999
Classical and atypical neuroleptics, and bone mineral density, in patients with schizophrenia.
    The International journal of neuroscience, 2002, Volume: 112, Issue:7

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Bone Density; Clopenthixol; Clozapine; Female; Fluphenazine; Haloperidol; Humans; Male; Olanzapine; Pirenzepine; Risperidone; Schizophrenia

2002
Augmentation of clozapine partial responders with conventional antipsychotics.
    Schizophrenia research, 2003, Mar-01, Volume: 60, Issue:1

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Synergism; Fluphenazine; Haloperidol; Humans; Middle Aged; Schizophrenia; Treatment Outcome

2003

Other Studies

79 other study(ies) available for fluphenazine and clozapine

ArticleYear
Synthesis and biological evaluation of some 2-amino-4-aryl-3H-1,5-benzodiazepine analogues of clozapine.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:9

    Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Avoidance Learning; Brain; Clozapine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Rats

1978
Synthesis and central nervous system activity of 2-arylidene-4-aminoalkyl-2H-1,4-benzoxazin-3(4H)-ones and related compounds.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:5

    Topics: Adenylyl Cyclase Inhibitors; Animals; Central Nervous System; Depression, Chemical; Female; In Vitro Techniques; Male; Olfactory Bulb; Oxazines; Rats; Receptors, Dopamine; Reflex; Structure-Activity Relationship

1977
Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
    Nature, 1991, Apr-18, Volume: 350, Issue:6319

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection

1991
(5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones . A series of novel potential antipsychotic agents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Animals; Antipsychotic Agents; Apomorphine; Ataxia; Avoidance Learning; Brain; Cebus; Chemical Phenomena; Chemistry; Dopamine; Male; Mice; Motor Activity; Movement Disorders; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Dopamine; Saimiri

1986
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin

1994
H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:3

    Topics: Animals; Antipsychotic Agents; Discriminant Analysis; Drug Evaluation, Preclinical; Forecasting; Humans; Protein Binding; Receptors, Histamine H1; Statistics, Nonparametric; Weight Gain

2003
Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.
    Journal of medicinal chemistry, 2005, Mar-24, Volume: 48, Issue:6

    Topics: Adenylyl Cyclases; Benzoxazines; Cell Line; Humans; Indoles; Ligands; Piperidines; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sulfonamides

2005
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
    Psychopharmacology, 2005, Volume: 179, Issue:2

    Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics.
    Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Antipsychotic Agents; Cell Line; CHO Cells; Cricetinae; Cricetulus; Histamine Antagonists; Humans; Radioligand Assay; Receptors, Histamine H3

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
[The influence of neuroleptic drugs on urinary excretion of non-protein nitrogen (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:2

    Topics: Amino Acids; Clopenthixol; Clozapine; Creatinine; Delayed-Action Preparations; Flupenthixol; Fluphenazine; Humans; Hydrogen-Ion Concentration; Ion Exchange Resins; Nitrogen; Procyclidine; Schizophrenia; Thioridazine; Tranquilizing Agents; Urea

1976
Brain homovanillic acid: regional changes over time with antipsychotic drugs.
    European journal of pharmacology, 1976, Volume: 39, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain; Caudate Nucleus; Chlorpromazine; Clozapine; Drug Tolerance; Fluphenazine; Homovanillic Acid; Hypothalamus; Limbic System; Male; Phenylacetates; Rabbits; Thioridazine; Time Factors

1976
Brain homovanillic acid: regional changes following chronic antipsychotic drug administration.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Animals; Antipsychotic Agents; Brain Chemistry; Chlorpromazine; Clozapine; Drug Tolerance; Fluphenazine; Haloperidol; Homovanillic Acid; Male; Phenylacetates; Rabbits; Thioridazine; Time Factors

1977
Adenylate cyclase from various dopaminergic areas of the brain and the action of antipsychotic drugs.
    Biochemical pharmacology, 1977, Sep-15, Volume: 26, Issue:18

    Topics: Adenylyl Cyclases; Amygdala; Animals; Antipsychotic Agents; Apomorphine; Brain; Caudate Nucleus; Clozapine; Dopamine; Fluphenazine; Isoproterenol; Loxapine; Median Eminence; Norepinephrine; Olfactory Bulb; Rats

1977
The effect of neuroleptic drugs on drinking induced by central administration of angiotensin or carbachol.
    Psychopharmacology, 1979, Feb-28, Volume: 60, Issue:3

    Topics: Angiotensin II; Animals; Antipsychotic Agents; Carbachol; Chlorpromazine; Clozapine; Dopamine; Drinking Behavior; Flupenthixol; Fluphenazine; Haloperidol; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pimozide; Rats; Sulpiride

1979
The effect of neuroleptics on brain tyrosine hydroxylase.
    Annali dell'Istituto superiore di sanita, 1978, Volume: 14, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Brain; Clozapine; Fluphenazine; Haloperidol; Hypothalamus; Male; Promethazine; Rats; Tyrosine 3-Monooxygenase

1978
Neuropharmacological and behavioral evaluation of prostaglandin E2 and 11-thiol-11-desoxy prostaglandin E2 in the mouse and rat.
    Psychopharmacology, 1978, May-31, Volume: 57, Issue:3

    Topics: Animals; Avoidance Learning; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Fluphenazine; Haloperidol; Humans; Male; Mice; Motor Activity; Physostigmine; Prostaglandins E; Prostaglandins E, Synthetic; Rats; Stereotyped Behavior; Thioridazine

1978
A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic systems.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Animals; Brain; Clozapine; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Fluphenazine; Haloperidol; Limbic System; Male; Metoclopramide; Pimozide; Rats; Stereotaxic Techniques; Sulpiride; Thioridazine; Tranquilizing Agents

1976
Catecholamine-sensitive adenylate cyclase in frontal cortex of primate brain.
    Brain research, 1976, Nov-12, Volume: 116, Issue:3

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Calcium; Catecholamines; Cerebral Cortex; Clozapine; Dopamine; Drug Combinations; Fluphenazine; Frontal Lobe; Guanosine Triphosphate; Haloperidol; Haplorhini; Isoproterenol; Macaca mulatta; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Dopamine; Sodium Fluoride; Time Factors

1976
Detection of the nueroleptic properties of clozapine, sulpiride and thioridazine.
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Synergism; Fluphenazine; Haloperidol; Humans; Isoquinolines; Male; Methyltyrosines; Pimozide; Rats; Spiro Compounds; Stereotyped Behavior; Succinimides; Sulpiride; Thioridazine; Tranquilizing Agents

1975
Plasma homovanillic acid and other predictors of clozapine response.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Clozapine; Fluphenazine; Homovanillic Acid; Humans; Schizophrenia

1992
The effects of typical and atypical neuroleptics on mitogen-induced T lymphocyte responsiveness.
    Biological psychiatry, 1991, Apr-01, Volume: 29, Issue:7

    Topics: Adult; Antigens, Differentiation; Antipsychotic Agents; CD5 Antigens; Clozapine; Female; Fluphenazine; Haloperidol; Humans; Lymphocyte Activation; Male; Schizophrenia; Schizophrenic Psychology; T-Lymphocytes; Thioridazine

1991
Chronic administration of typical, but not atypical neuroleptics induce persisting alterations in rest-activity cycles in rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Animals; Antipsychotic Agents; Clozapine; Drinking; Female; Fluphenazine; Haloperidol; Motor Activity; Raclopride; Rats; Rats, Inbred Strains; Salicylamides

1990
3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:2

    Topics: 4-Butyrolactone; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Buspirone; Carbazoles; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Fluphenazine; Haloperidol; Male; Molindone; Pargyline; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Regression Analysis

1986
In vivo potencies of antipsychotic drugs in blocking alpha 1 noradrenergic and dopamine D2 receptors: implications for drug mechanisms of action.
    Life sciences, 1986, Dec-29, Volume: 39, Issue:26

    Topics: Animals; Antipsychotic Agents; Binding, Competitive; Chlorpromazine; Clozapine; Fluphenazine; Haloperidol; Kinetics; Male; Prazosin; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Dopamine; Thioridazine

1986
Apparent neuroleptic malignant syndrome with clozapine and lithium.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:8

    Topics: Adult; Bipolar Disorder; Clozapine; Dibenzazepines; Drug Therapy, Combination; Fluphenazine; Humans; Lithium; Lithium Carbonate; Male; Neuroleptic Malignant Syndrome

1986
Clozapine plasma levels determined by high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography, 1988, Jun-24, Volume: 428, Issue:1

    Topics: Chromatography, High Pressure Liquid; Clozapine; Dibenzazepines; Fluphenazine; Humans; Spectrophotometry, Ultraviolet

1988
Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Binding, Competitive; Brain; Chlorpromazine; Clozapine; Fluphenazine; Guinea Pigs; Haloperidol; Haplorhini; Humans; In Vitro Techniques; Perphenazine; Phenothiazines; Promazine; Rats; Receptors, Cholinergic; Schizophrenia; Thioridazine; Trifluoperazine; Triflupromazine

1974
Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Chlorpromazine; Clozapine; Desipramine; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imipramine; Male; Nortriptyline; Promethazine; Rats; Sodium Chloride; Thioridazine; Trifluoperazine

1980
[Treatment of therapeutically resistant paranoid schizophrenic patients with Moditen-depot combined with other psychotropic drugs and Leponex].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:8

    Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Clozapine; Delayed-Action Preparations; Depression; Dibenzazepines; Drug Therapy, Combination; Female; Fluphenazine; Humans; Male; Middle Aged; Psychotropic Drugs; Remission, Spontaneous; Schizophrenia, Paranoid

1980
Regional selectivity of neuroleptic drugs: an argument for site specificity.
    Brain research bulletin, 1983, Volume: 11, Issue:2

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Corpus Striatum; Fluphenazine; Haloperidol; Limbic System; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Thioridazine

1983
Chronic fluphenazine and clozapine elicit opposite changes in brain muscarinic receptor binding: implications for understanding tardive dyskinesia.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Clozapine; Corpus Striatum; Dibenzazepines; Dyskinesia, Drug-Induced; Fluphenazine; Hippocampus; Male; Mice; Pilocarpine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic

1983
An examination of methodological refinements, clozapine and fluphenazine in the anhedonia paradigm.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:5

    Topics: Animals; Clozapine; Conditioning, Operant; Dibenzazepines; Dose-Response Relationship, Drug; Emotions; Extinction, Psychological; Fluphenazine; Male; Pimozide; Rats; Rats, Inbred Strains; Reinforcement Schedule

1982
Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine.
    European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3

    Topics: Animals; Antipsychotic Agents; Clozapine; Dextroamphetamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Imidazoles; Indoles; Locomotion; Male; Motor Activity; Prazosin; Rats; Rats, Wistar; Ritanserin

1995
[Is there a special indication for fluphenazine in therapy refractory hallucinations?].
    Der Nervenarzt, 1994, Volume: 65, Issue:11

    Topics: Clozapine; Delusions; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluphenazine; Hallucinations; Humans; Schizophrenia; Schizophrenia, Paranoid; Schizophrenic Psychology

1994
Effect of chronic neuroleptic treatment on central and peripheral muscarinic receptors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1

    Topics: Animals; Antipsychotic Agents; Atropine; Cell Membrane; Clozapine; Corpus Striatum; Fluphenazine; Male; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Time Factors; Urinary Bladder

1993
Clozapine reverses cocaine craving in a treatment-resistant mentally ill chemical abuser: a case report and a hypothesis.
    The Journal of nervous and mental disease, 1994, Volume: 182, Issue:10

    Topics: Adult; Clozapine; Cocaine; Comorbidity; Diagnosis, Dual (Psychiatry); Drug Therapy, Combination; Fluphenazine; Humans; Lithium; Male; Psychotic Disorders; Substance-Related Disorders; Treatment Outcome

1994
Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases glutamic acid decarboxylase mRNA in rat striatum.
    Neuroscience letters, 1993, Feb-19, Volume: 150, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Base Sequence; Blotting, Northern; Clozapine; Corpus Striatum; Depression, Chemical; Dopamine D2 Receptor Antagonists; Fluphenazine; Glutamate Decarboxylase; Haloperidol; In Vitro Techniques; Male; Molecular Sequence Data; Oligodeoxyribonucleotides; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; RNA Probes; RNA, Messenger

1993
Platelet dysfunction associated with clozapine therapy.
    Southern medical journal, 1993, Volume: 86, Issue:10

    Topics: Amobarbital; Blood Cell Count; Clozapine; Delayed-Action Preparations; Diazepam; Drug Monitoring; Drug Therapy, Combination; Epistaxis; Fluphenazine; Hemoglobins; Humans; Male; Middle Aged; Platelet Count; Schizophrenia, Paranoid; Thrombocytopenia

1993
The interaction of clozapine with the meta-chlorophenylpiperazine (mCPP) discriminative stimulus.
    Life sciences, 1996, Volume: 58, Issue:24

    Topics: Animals; Antipsychotic Agents; Clozapine; Discrimination, Psychological; Drug Interactions; Fluphenazine; Piperazines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin

1996
Cognitive dysfunction in schizophrenia: comparison of treatment with atypical antipsychotic agents and conventional neuroleptic drugs.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6 Suppl 2

    Topics: Clozapine; Cognition; Fluphenazine; Haloperidol; Humans; Maze Learning; Risperidone; Schizophrenia

1996
Differential expression of c-fos mRNA in rat prefrontal cortex, striatum, N. accumbens and lateral septum after typical and atypical antipsychotics: an in situ hybridization study.
    Neurochemistry international, 1996, Volume: 29, Issue:4

    Topics: Animals; Antipsychotic Agents; Aripiprazole; Brain; Clozapine; Corpus Striatum; Fluphenazine; Genes, fos; Haloperidol; In Situ Hybridization; Nucleus Accumbens; Piperazines; Prefrontal Cortex; Quinolones; Rats; RNA, Messenger; Septum Pellucidum; Sulpiride

1996
The brain metabolic patterns of clozapine- and fluphenazine-treated patients with schizophrenia during a continuous performance task.
    Archives of general psychiatry, 1997, Volume: 54, Issue:5

    Topics: Adult; Auditory Perception; Brain; Clozapine; Deoxyglucose; Fluorodeoxyglucose F18; Fluphenazine; Glucose; Humans; Limbic System; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Task Performance and Analysis; Temporal Lobe; Tomography, Emission-Computed

1997
Attenuation of antipsychotic-induced hyperprolactinemia with clozapine.
    Journal of child and adolescent psychopharmacology, 1997,Spring, Volume: 7, Issue:1

    Topics: Adolescent; Amenorrhea; Antipsychotic Agents; Bromocriptine; Clozapine; Female; Fluphenazine; Galactorrhea; Haloperidol; Humans; Hyperprolactinemia; Prolactin; Psychotic Disorders; Thioridazine

1997
Effect of clozapine on dopamine-induced inhibition of prolactin release from cultured rat pituitary cells.
    Pharmacological research, 1997, Volume: 35, Issue:3

    Topics: Animals; Antipsychotic Agents; Cells, Cultured; Chlorpromazine; Clozapine; Dopamine; Fluphenazine; Humans; Pituitary Gland; Prolactin; Rats; Receptors, Dopamine

1997
Long-term effects of S(+)N-n-propylnorapomorphine compared with typical and atypical antipsychotics: differential increases of cerebrocortical D2-like and striatolimbic D4-like dopamine receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1997, Volume: 17, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Cell Line; Cerebral Cortex; Clozapine; Dopamine Agonists; Drug Design; Fluphenazine; Limbic System; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4

1997
Norepinephrine and schizophrenia: a new hypothesis for antipsychotic drug action.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Antipsychotic Agents; Clozapine; Fluphenazine; Humans; Methoxyhydroxyphenylglycol; Norepinephrine; Regression Analysis; Schizophrenia; Time Factors

1998
A histochemical demonstration of altered cytochrome oxidase activity in the rat brain by neuroleptics.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1998, Volume: 8, Issue:1

    Topics: Animals; Antipsychotic Agents; Brain; Clozapine; Densitometry; Electron Transport Complex IV; Fluphenazine; Haloperidol; Histocytochemistry; Male; Rats; Rats, Sprague-Dawley

1998
Neuroleptic malignant syndrome during low dosed neuroleptic medication in first-episode psychosis: a case report.
    Psychopharmacology, 1999, Volume: 144, Issue:4

    Topics: Adult; Antipsychotic Agents; Clozapine; Dantrolene; Female; Fluphenazine; Humans; Muscle Relaxants, Central; Neuroleptic Malignant Syndrome; Psychotic Disorders

1999
Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats.
    European journal of pharmacology, 1999, Aug-20, Volume: 379, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Antipsychotic Agents; Catalepsy; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fluphenazine; Haloperidol; Male; Mice; Orientation; Peptic Ulcer; Peptide Fragments; Proteins; Rats; Rats, Wistar; Sulpiride; Time Factors

1999
Paradoxical effect of neuroleptic drugs on prolactin secretion by rat pituitary cell cultures.
    Life sciences, 1999, Volume: 65, Issue:14

    Topics: Animals; Antipsychotic Agents; Cell Survival; Cells, Cultured; Clozapine; Female; Fluphenazine; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Secretory Rate

1999
Dopamine receptor antagonists modulate glucose uptake in rat pheochromocytoma (PC12) cells.
    Neuroscience letters, 1999, Oct-29, Volume: 274, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Benzazepines; Biological Transport; Chlorpromazine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; Fluphenazine; Glucose; Haloperidol; PC12 Cells; Pimozide; Rats; Receptors, Dopamine D2; Spiperone; Sulpiride; Tritium

1999
Thrombocytopenia associated with clozapine and fluphenazine.
    Nordic journal of psychiatry, 2001, Volume: 55, Issue:6

    Topics: Adult; Antipsychotic Agents; Clozapine; Fluphenazine; Humans; Male; Schizophrenia; Thrombocytopenia

2001
Effects of atypical antipsychotics on vertebrate neuromuscular transmission.
    Neuropharmacology, 2002, Volume: 42, Issue:5

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Fluphenazine; In Vitro Techniques; Membrane Potentials; Motor Endplate; Neuromuscular Junction; Olanzapine; Pirenzepine; Rana pipiens; Rana temporaria; Risperidone; Sulpiride; Synaptic Transmission

2002
Sexual side effects of novel antipsychotic medications.
    Schizophrenia research, 2002, Jul-01, Volume: 56, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Clozapine; Erectile Dysfunction; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Sexual Behavior

2002
Clozapine and tardive dyskinesia.
    The American journal of psychiatry, 2003, Volume: 160, Issue:3

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Fluphenazine; Haloperidol; Humans; Longitudinal Studies; Schizophrenia, Paranoid

2003
Rehospitalization risk with second-generation and depot antipsychotics.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2003, Volume: 15, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clozapine; Data Collection; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Humans; Male; Olanzapine; Patient Readmission; Pirenzepine; Risperidone; Schizophrenia; Secondary Prevention; Time Factors; Treatment Outcome

2003
Clozapine as a first treatment for schizophrenia.
    The American journal of psychiatry, 2003, Volume: 160, Issue:8

    Topics: Adolescent; Adult; Antipsychotic Agents; Clozapine; Drug Administration Schedule; Female; Fluphenazine; Follow-Up Studies; Hospitalization; Humans; Male; Middle Aged; Patient Dropouts; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Survival Analysis; Treatment Outcome

2003
The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy.
    Ideggyogyaszati szemle, 2004, Nov-20, Volume: 57, Issue:11-12

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Brain; Clopenthixol; Clozapine; Dibenzothiazepines; Electric Impedance; Electroconvulsive Therapy; Electroencephalography; Electromyography; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Olanzapine; Quetiapine Fumarate; Risperidone; Seizures; Sulpiride

2004
Second-generation antipsychotic drugs, olanzapine, quetiapine, and clozapine enhance neurite outgrowth in PC12 cells via PI3K/AKT, ERK, and pertussis toxin-sensitive pathways.
    Journal of molecular neuroscience : MN, 2005, Volume: 27, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Chromones; Clozapine; Dibenzothiazepines; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluphenazine; Haloperidol; Humans; Morpholines; Nerve Growth Factor; Neurites; Olanzapine; PC12 Cells; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quetiapine Fumarate; Rats

2005
Repeated antipsychotic drug exposure in developing rats: dopamine receptor effects.
    Synapse (New York, N.Y.), 2006, Volume: 59, Issue:2

    Topics: Age Factors; Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Fluphenazine; Image Processing, Computer-Assisted; Male; Olanzapine; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Dopamine

2006
Importance of oral glucose tolerance test in patient with schizophrenia.
    Psychiatria Danubina, 2005, Volume: 17, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Fluphenazine; Glucose Tolerance Test; Humans; Male; Schizophrenia; Weight Gain

2005
Switching as only temporal solution for patients with antipsychotic-associated diabetes: further observations.
    Psychiatria Danubina, 2007, Volume: 19, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Blood Glucose; Body Mass Index; Clozapine; Diabetes Mellitus, Type 2; Dibenzothiazepines; Diet, Diabetic; Drug Therapy, Combination; Female; Fluphenazine; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Mass Screening; Quetiapine Fumarate; Risk Factors; Schizophrenia

2007
Glycopyrrolate for clozapine-induced sialorrhea.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Oct-01, Volume: 31, Issue:7

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Clozapine; Fluphenazine; Glycopyrrolate; Humans; Male; Muscarinic Antagonists; Psychotic Disorders; Sialorrhea; Valproic Acid

2007
Treatment compliance of outpatients with schizophrenia: patient's attitudes, demographic, clinical and therapeutic variables.
    Psychiatria Danubina, 2008, Volume: 20, Issue:1

    Topics: Administration, Oral; Adult; Age Factors; Ambulatory Care; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Delayed-Action Preparations; Female; Fluphenazine; Haloperidol; Health Knowledge, Attitudes, Practice; Humans; Long-Term Care; Male; Middle Aged; Patient Compliance; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Yugoslavia

2008
Antipsychotic drugs up-regulate tryptophan hydroxylase in ADF neurons of Caenorhabditis elegans: role of calcium-calmodulin-dependent protein kinase II and transient receptor potential vanilloid channel.
    Journal of neuroscience research, 2008, Aug-15, Volume: 86, Issue:11

    Topics: Adaptation, Physiological; Animals; Animals, Genetically Modified; Antipsychotic Agents; Behavior, Animal; Benzodiazepines; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Chloride Channels; Clozapine; Fluphenazine; Microscopy, Fluorescence; Neurons; Olanzapine; Receptors, Serotonin, 5-HT2; Serotonin; Trifluoperazine; TRPV Cation Channels; Tryptophan Hydroxylase; Up-Regulation

2008
The role of CYP2D6 and TaqI A polymorphisms in malignant neuroleptic syndrome: two case reports with three episodes.
    Psychiatria Danubina, 2010, Volume: 22, Issue:1

    Topics: Adult; Alleles; Antipsychotic Agents; Bipolar Disorder; Clozapine; Cytochrome P-450 CYP2D6; Dibenzothiazepines; Drug Therapy, Combination; Fluphenazine; Genetic Carrier Screening; Genotype; Haloperidol; Humans; Lithium Carbonate; Male; Neuroleptic Malignant Syndrome; Perazine; Polymorphism, Genetic; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Recurrence; Risperidone

2010
Evaluation of five antischizophrenic agents against Toxoplasma gondii in human cell cultures.
    The Journal of parasitology, 2011, Volume: 97, Issue:1

    Topics: Antipsychotic Agents; Cell Line; Clozapine; Fibroblasts; Fluphenazine; Haloperidol; Humans; Schizophrenia; Thioridazine; Toxoplasma; Toxoplasmosis; Trifluoperazine

2011
Clinical aspects of comorbid schizophrenia and idiopathic Parkinson's disease.
    Clinical schizophrenia & related psychoses, 2014, Volume: 8, Issue:1

    Topics: Antiparkinson Agents; Antipsychotic Agents; Brain; Carbidopa; Catechols; Clozapine; Diagnosis, Differential; Fluphenazine; Follow-Up Studies; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome

2014
Schizophrenia and co-occurring substance use disorder: reward, olfaction and clozapine.
    Schizophrenia research, 2014, Volume: 155, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Clozapine; Female; Fluphenazine; Haloperidol; Humans; Male; Middle Aged; Odorants; Psychiatric Status Rating Scales; Reward; Schizophrenia; Schizophrenic Psychology; Smell; Substance-Related Disorders

2014
Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α
    Neuropharmacology, 2017, Volume: 116

    Topics: Animals; Antipsychotic Agents; beta-Arrestin 1; beta-Arrestin 2; Caveolin 1; Chlorpromazine; Clozapine; Cyclic AMP; Endocytosis; Fibroblasts; Fluphenazine; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Molecular Docking Simulation; Norepinephrine; Receptors, Adrenergic, alpha-2

2017
Characterization hiPSC-derived neural progenitor cells and neurons to investigate the role of NOS1AP isoforms in human neuron dendritogenesis.
    Molecular and cellular neurosciences, 2020, Volume: 109

    Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Clozapine; Dendrites; Drug Evaluation, Preclinical; Fluphenazine; Gene Expression Regulation; Glutamic Acid; Haloperidol; Humans; Induced Pluripotent Stem Cells; Ion Channels; Nerve Tissue Proteins; Neural Stem Cells; Neurons; Oligopeptides; Patch-Clamp Techniques; Protein Isoforms; Schizophrenia; Serine

2020
Letter to the Editor: Rethinking The Cost Of Antipsychotic Treatment: The Average Cost Of The Drugs Used In Turkey In 2020.
    Turk psikiyatri dergisi = Turkish journal of psychiatry, 2022,Summer, Volume: 33, Issue:2

    Topics: Adenosine Monophosphate; Adult; Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Chlorpromazine; Clopenthixol; Clozapine; Flupenthixol; Fluphenazine; Haloperidol; Humans; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Pimozide; Quetiapine Fumarate; Risperidone; Sulpiride; Trifluoperazine

2022
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016