fluperlapine has been researched along with clozapine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruhwyler, J; Chleide, EM; Damas, J; Delarge, JE; Inarejos, MO; Liégeois, JF; Mercier, MG; Nguyen, TP; Rogister, FA | 1 |
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| Bruhwyler, J; Chleide, EM; Damas, J; Delarge, JE; Liégeois, JF; Mercier, MG; Nguyen, TP; Rogister, FA | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M | 1 |
| Fischer, V; Maurer, G; Tynes, RE; Vogels, B | 1 |
| Matsubara, S; Meltzer, HY | 1 |
| Angelucci, L; Imperato, A | 1 |
| Dichgans, J; Scholz, E | 1 |
| Burki, HR | 1 |
| Andersen, PH; Braestrup, C | 1 |
| Gudelsky, GA; Koenig, JI; Koyama, T; Meltzer, HY; Ohmori, T; Simonovic, M | 1 |
| Eichenberger, E | 1 |
| Duhan, NL; Farber, NB; Foster, J; Olney, JW | 1 |
| Fu, JM; Rakhit, S; Tehim, A; Uetrecht, J; Zahid, N | 1 |
| Gardner, I; Lai, WG; Uetrecht, JP; Zahid, N | 1 |
16 other study(ies) available for fluperlapine and clozapine
| Article | Year |
|---|---|
Pyridobenzoxazepine and pyridobenzothiazepine derivatives as potential central nervous system agents: synthesis and neurochemical study.
Topics: Animals; Antipsychotic Agents; Binding Sites; Dogs; Oxazepines; Pyridines; Rats; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Serotonin; Structure-Activity Relationship; Thiazepines | 1994 |
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
New pyridobenzodiazepine derivatives as potential antipsychotics: synthesis and neurochemical study.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding Sites; Dogs; Rats; Structure-Activity Relationship | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
The antipsychotic clozapine is metabolized by the polymorphic human microsomal and recombinant cytochrome P450 2D6.
Topics: Base Sequence; Clozapine; Cytochrome P-450 Enzyme System; Dealkylation; Dextromethorphan; Dibenzazepines; Humans; In Vitro Techniques; Microsomes, Liver; Molecular Sequence Data; Recombinant Proteins | 1992 |
Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antipsychotic Agents; Butyrophenones; Cerebral Cortex; Chlorpromazine; Clozapine; Dibenzazepines; Dibenzothiazepines; Down-Regulation; Flupenthixol; Kinetics; Loxapine; Male; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Time Factors | 1989 |
The effects of clozapine and fluperlapine on the in vivo release and metabolism of dopamine in the striatum and in the prefrontal cortex of freely moving rats.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Male; Rats; Rats, Inbred Strains | 1989 |
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1985 |
Effects of fluperlapine on dopaminergic systems in rat brain.
Topics: Animals; Brain; Brain Chemistry; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Haloperidol; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2 | 1986 |
Evidence for different states of the dopamine D1 receptor: clozapine and fluperlapine may preferentially label an adenylate cyclase-coupled state of the D1 receptor.
Topics: Adenylyl Cyclases; Animals; Benzazepines; Binding Sites; Clozapine; Colforsin; Corpus Striatum; Dibenzazepines; Dopamine; Humans; Kinetics; Phospholipases A; Phospholipases A2; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Synaptic Membranes | 1986 |
Differential effects of haloperidol, clozapine, and fluperlapine on tuberoinfundibular dopamine neurons and prolactin secretion in the rat.
Topics: Animals; Clozapine; Dibenzazepines; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Hypothalamus; Median Eminence; Neurons; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Pharmacology of fluperlapine compared with clozapine.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain Chemistry; Clozapine; Dibenzazepines; Dopamine; Electroencephalography; Homovanillic Acid; Humans; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1984 |
Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzazepines; Dibenzoxazepines; Dizocilpine Maleate; Female; N-Methylaspartate; Nervous System; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Structural features associated with reactive metabolite formation in clozapine analogues.
Topics: Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Binding Sites; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Dibenzazepines; Glutathione; Granulocytes; Humans; Hydrogen Peroxide; Hypochlorous Acid; Lymphocyte Activation; Mass Spectrometry; Neutrophils; Nitrogen; Olanzapine; Oxidation-Reduction; Peroxidase; Pirenzepine; Structure-Activity Relationship | 1997 |
Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
Topics: Acetylcysteine; Agranulocytosis; Binding, Competitive; Clozapine; Dibenzazepines; Glutathione; Hemocyanins; Humans; Hypochlorous Acid; Immune Sera; Immunoblotting; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding | 2000 |