Compounds > flupenthixol
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flupenthixol and cp 65,526

flupenthixol has been researched along with cp 65,526 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambudkar, SV; Dey, S; Gottesman, MM; Pastan, I; Ramachandra, M1
Dey, S; Gottesman, MM; Hafkemeyer, P; Pastan, I1
Dey, S; Ghosh, P; Maki, N; Moitra, K1
Dey, S; Maki, N1

Other Studies

4 other study(ies) available for flupenthixol and cp 65,526

ArticleYear
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Sep-30, Volume: 94, Issue:20

    Topics: 3T3 Cells; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Biological Transport; Cell Line; Cyclosporine; Flupenthixol; Humans; Insecta; Iodine Radioisotopes; Mice; Models, Biological; Prazosin; Radioligand Assay; Vanadates; Vinblastine

1997
A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol.
    Biochemistry, 1999, May-18, Volume: 38, Issue:20

    Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Dopamine Antagonists; Flupenthixol; HeLa Cells; Humans; Hydrolysis; Iodine Radioisotopes; Mutagenesis, Site-Directed; Phenylalanine; Photoaffinity Labels; Prazosin; Receptors, Dopamine; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured; Verapamil

1999
Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Catalytic Domain; Cell Line; Cell Membrane; Flupenthixol; Humans; Hydrolysis; Insecta; Ligands; Molecular Conformation; Prazosin; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thioxanthenes; Time Factors; Trypsin; Vanadates

2006
Biochemical and pharmacological properties of an allosteric modulator site of the human P-glycoprotein (ABCB1).
    Biochemical pharmacology, 2006, Jul-14, Volume: 72, Issue:2

    Topics: Allosteric Regulation; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Flupenthixol; Humans; Phenothiazines; Prazosin; Xanthines

2006