fluoxetine and warfarin

fluoxetine has been researched along with warfarin in 27 studies

Research

Studies (27)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.70)	18.7374
1990's	5 (18.52)	18.2507
2000's	4 (14.81)	29.6817
2010's	16 (59.26)	24.3611
2020's	1 (3.70)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Carmichael, R; Lemberger, L; Rowe, H	1
Gibaldi, M	1
Claire, RJ; Cram, DL; Servis, ME	1
Hanger, HC; Thomas, F	1
Brown, PJ; Dewar, MS; Gammack, NS; Woolfrey, S	1
Anderson, ML; Ford, MA; Jaskar, DW; Rindone, JP	1
Brookes, PS; Gray, DA; Karcz, MK; Lopes, CM; Nehrke, KW; Williams, DM; Wojtovich, AP	1
Gorski, JC; Lindamood, C; Ortiz, S; Rackley, R; Shaw, A	1
Donato-Brown, D; Haji Mohd Yasin, NA; Taha, A	1
Aruna Teja, G; Bhaskara Rao, K; Gupta, S; Modukuri, RK; Sashidhara, KV; Shukla, S; Singh, S	1
Ahemad, N; Dong, AN; Ong, CE; Palanisamy, UD; Pan, Y; Yiap, BC	1

Reviews

2 review(s) available for fluoxetine and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug interactions: Part I. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5 Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine	1992

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Drug interactions: Part I.

The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5

Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine

1992

Trials

1 trial(s) available for fluoxetine and warfarin

Article	Year
Lack of effect of fluoxetine on the hypoprothrombinemic response of warfarin. Journal of clinical psychopharmacology, 1997, Volume: 17, Issue:2 Topics: Aged; Aged, 80 and over; Analysis of Variance; Anticoagulants; Drug Interactions; Fluoxetine; Humans; Hypoprothrombinemias; Middle Aged; Prothrombin Time; Selective Serotonin Reuptake Inhibitors; Warfarin	1997

Other Studies

24 other study(ies) available for fluoxetine and warfarin

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
The effect of fluoxetine on warfarin metabolism in the rat and man. Life sciences, 1978, Aug-28, Volume: 23, Issue:8 Topics: Animals; Fluoxetine; Half-Life; Humans; Male; Propylamines; Prothrombin; Rats; Time Factors; Warfarin	1978
Potential interaction between warfarin sodium and fluoxetine. The American journal of psychiatry, 1991, Volume: 148, Issue:11 Topics: Drug Interactions; Ecchymosis; Female; Fluoxetine; Humans; Warfarin	1991
Fluoxetine and warfarin interactions. The New Zealand medical journal, 1995, Apr-26, Volume: 108, Issue:998 Topics: Aged; Drug Interactions; Fluoxetine; Humans; Male; Middle Aged; Warfarin	1995
Fluoxetine-warfarin interaction. BMJ (Clinical research ed.), 1993, Jul-24, Volume: 307, Issue:6898 Topics: Blood Coagulation; Drug Interactions; Fluoxetine; Humans; Male; Middle Aged; Warfarin	1993
A novel mitochondrial K(ATP) channel assay. Circulation research, 2010, Apr-16, Volume: 106, Issue:7 Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Second-Generation; Benzothiazoles; Biological Assay; Coumarins; Fluorescent Dyes; Fluoxetine; Glycine; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Kinetics; Male; Mitochondria, Heart; Mitochondrial Swelling; Myocardial Reperfusion Injury; Osmosis; Perfusion; Phosphatidylinositol 4,5-Diphosphate; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Fluorescence; Thallium; Uridine Diphosphate	2010
Effects of commonly administered agents and genetics on nebivolol pharmacokinetics: drug-drug interaction studies. Journal of clinical pharmacology, 2011, Volume: 51, Issue:4 Topics: Adult; Antihypertensive Agents; Benzopyrans; Cytochrome P-450 CYP2D6; Digoxin; Drug Interactions; Ethanolamines; Female; Fluoxetine; Furosemide; Genotype; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged; Nebivolol; Ramipril; Warfarin; Young Adult	2011
Non-traumatic spontaneous spinal subdural haematoma. The New Zealand medical journal, 2012, Oct-12, Volume: 125, Issue:1363 Topics: Aged; Antifibrinolytic Agents; Back Pain; Blood Coagulation Factors; Combined Modality Therapy; Decompression, Surgical; Dexamethasone; Early Diagnosis; Early Medical Intervention; Fluoxetine; Glucocorticoids; Hematoma, Subdural, Spinal; Humans; Laminectomy; Magnetic Resonance Imaging; Male; Paraplegia; Spinal Cord Compression; Treatment Outcome; Urinary Retention; Vitamin K; Warfarin	2012
Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity. Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2 Topics: Animals; Antidepressive Agents; Behavior, Animal; Coumarins; Depression; Dose-Response Relationship, Drug; Drug Design; Fluoxetine; Male; Mice; Models, Molecular; Molecular Structure; Motor Activity; Pyrans; Structure-Activity Relationship; Swimming	2015
The Molecular and Enzyme Kinetic Basis for Altered Activity of Three Cytochrome P450 2C19 Variants Found in the Chinese Population. Current molecular pharmacology, 2020, Volume: 13, Issue:3 Topics: Alleles; Amino Acid Sequence; Asian People; Catalytic Domain; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Fluoxetine; Humans; Ketoconazole; Kinetics; Loratadine; Models, Molecular; Molecular Docking Simulation; Mutagenesis, Site-Directed; Nitriles; Omeprazole; Polymorphism, Genetic; Protein Conformation; Protein Isoforms; Recombinant Proteins; Sertraline; Substrate Specificity	2020