fluoxetine and thiophenes

fluoxetine has been researched along with thiophenes in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (14.89)18.2507
2000's18 (38.30)29.6817
2010's21 (44.68)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Bertrand, J; Costentin, J; Simon, P1
Dziedzicka-Wasylewska, M; Maj, J; Rogoz, R; Rogóz, Z; Skuza, G1
Cistarelli, JM; Gobert, A; Millan, MJ; Rivet, JM1
Lakoski, JM; Smith, JE2
Cistarelli, L; Gobert, A; Melon, C; Millan, MJ; Rivet, JM1
Lucki, I; Rénéric, JP1
Demitrack, MA; Goldstein, DJ; Lu, Y; Mallinckrodt, C1
Audia, JE; Katofiasc, MA; Nissen, J; Thor, KB1
Dawson, LA; Li, P1
Hemrick-Luecke, SK; Iyengar, S; Simmons, RM; Webster, AA; Xu, JY1
Greist, J; Mallinckrodt, CH; McNamara, RK; Raskin, J; Rayamajhi, JN1
Fava, M; Hazen, E1
Archer, SL; Michelakis, ED1
Eckert, L; Lançon, C1
Cookson, J; Desaiah, D; Gilaberte, I; Kajdasz, DK1
Eastwood, BJ; Jones, CK; Need, AB; Shannon, HE1
Platt, DM; Rowlett, JK; Spealman, RD1
Detke, MJ; Faries, DE; Mallinckrodt, CH; Meyers, AL; Prakash, A1
Detke, MJ; Ossanna, MJ; Pritchett, YL; Swindle, RW; Thase, ME; Xu, J1
Detke, MJ; Fava, M; Houston, JP; Mallinckrodt, CH; Prakash, A; Swindle, R1
Carvalho, LA; Gorenstein, C; Markus, RP; Moreno, R; Pariante, C1
Apfeldorf, WJ; Cullen, CE; Eide, CE; Lu, BY; Williams, CC1
Baker, SJ; Boyce-Rustay, JM; Decker, MW; Honore, P; Kohnken, R; Simler, GH; Wensink, EJ; Zhong, C1
Apazoglou, K; Farley, S; Giros, B; Tzavara, ET; Witkin, JM1
Argento, V; Blagodatny, M; Liu, PT; Skudlarska, B1
Lucassen, PJ; Marlatt, MW; van Praag, H1
Kourti, PV; Samanidou, VF1
Chapman, A; Delivuk, M; Gartlehner, G; Gaynes, BN; Kaminski, A; Thaler, K1
Chen, NH; Li, J; Liu, Y; Sun, JD; Yuan, YH1
Kovatsi, L; Livanos, A; Njau, S; Pantazidou, K; Samanidou, V1
Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ1
Barbui, C; Cipriani, A; Furukawa, TA; Koesters, M; Nosè, M; Omori, IM; Purgato, M; Trespidi, C1
Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR1
Fang, Q; Hu, YH; Li, S; Wu, FF; Wu, J; Xie, LJ; Yang, LY; Zhou, JN1
Atkinson, SD; Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q1
Bangs, ME; Emslie, GJ; March, JS; Pangallo, BA; Prakash, A; Zhang, Q1
Calow, AD; Fernández, E; Whiting, A1
Gu, S; Guo, J; Luo, H; Qu, W; Tang, Q1
Buchwald, SL; Shi, SL1
Hu, Q; Imamoto, T; Liu, Y; Zhang, W; Zhang, Z1
Dong, C; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C; Yao, W; Zhang, JC2
Dong, C; Fujita, Y; Futamura, T; Hashimoto, K; Ma, M; Ohgi, Y; Ren, Q; Yang, C1
Banas, SM; Belmer, A; Diaz, SL; Doly, S; Fernandez, SP; Guiard, BP; Mameli, M; Maroteaux, L; Moutkine, I; Muzerelle, A; Pitychoutis, PM; Quentin, E; Roumier, A; Tchenio, A1
Chapman, A; Gartlehner, G; Gaynes, BN; Nussbaumer-Streit, B; Probst, T; Sönnichsen, A; Thaler, K; Winkler, D1

Reviews

6 review(s) available for fluoxetine and thiophenes

ArticleYear
An evidence-based approach to the management of pulmonary arterial hypertension.
    Current opinion in cardiology, 2006, Volume: 21, Issue:4

    Topics: Antihypertensive Agents; Benzamides; Bosentan; Calcium Channel Blockers; Comorbidity; Dichloroacetic Acid; Drug Therapy, Combination; Epoprostenol; Evidence-Based Medicine; Fluoxetine; Humans; Hypertension, Pulmonary; Iloprost; Imatinib Mesylate; Isoxazoles; Phosphodiesterase Inhibitors; Piperazines; Prostaglandins, Synthetic; Pulmonary Artery; Purines; Pyrimidines; Randomized Controlled Trials as Topic; Sildenafil Citrate; Simvastatin; Sulfonamides; Sulfones; Thiophenes; Vasodilator Agents

2006
Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons.
    BMC psychiatry, 2006, Jul-24, Volume: 6

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder, Major; Duloxetine Hydrochloride; Fluoxetine; Humans; Randomized Controlled Trials as Topic; Regression Analysis; Thiophenes; Treatment Outcome; Venlafaxine Hydrochloride

2006
Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6

    Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Placebos; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2007
Second-generation antidepressants for seasonal affective disorder.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Phototherapy; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes

2011
Duloxetine versus other anti-depressive agents for depression.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Antidepressive Agents; Citalopram; Cyclohexanols; Depression; Desvenlafaxine Succinate; Dibenzothiazepines; Duloxetine Hydrochloride; Fluoxetine; Humans; Paroxetine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Thiophenes; Venlafaxine Hydrochloride

2012
Second-generation antidepressants for treatment of seasonal affective disorder.
    The Cochrane database of systematic reviews, 2021, 03-04, Volume: 3

    Topics: Adult; Antidepressive Agents, Second-Generation; Bias; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Morpholines; Observational Studies as Topic; Phototherapy; Placebos; Quality of Life; Randomized Controlled Trials as Topic; Reboxetine; Seasonal Affective Disorder; Thiophenes; Treatment Outcome

2021

Trials

8 trial(s) available for fluoxetine and thiophenes

ArticleYear
Duloxetine in the treatment of major depressive disorder: a double-blind clinical trial.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Blood Pressure; Body Weight; Depressive Disorder, Major; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2002
Incidence and duration of antidepressant-induced nausea: duloxetine compared with paroxetine and fluoxetine.
    Clinical therapeutics, 2004, Volume: 26, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Europe; Female; Fluoxetine; Humans; Male; Middle Aged; Nausea; Paroxetine; Prevalence; Severity of Illness Index; Sex Factors; Thiophenes; Time Factors; United States

2004
Treatment benefits of duloxetine in major depressive disorder as assessed by number needed to treat.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Treatment Outcome

2006
Differential antidepressant symptom efficacy: placebo-controlled comparisons of duloxetine and SSRIs (fluoxetine, paroxetine, escitalopram).
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Thiophenes; Treatment Outcome

2007
Effect of antidepressants on melatonin metabolite in depressed patients.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hypericum; Male; Melatonin; Middle Aged; Plant Extracts; Severity of Illness Index; Thiophenes; Treatment Outcome

2009
A double-blind efficacy and safety study of duloxetine flexible dosing in children and adolescents with major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome

2014
A double-blind efficacy and safety study of duloxetine fixed doses in children and adolescents with major depressive disorder.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Adolescent; Antidepressive Agents; Child; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Suicidal Ideation; Suicide; Thiophenes; Treatment Outcome

2014
Effects of olanzapine-fluoxetine combination treatment of major depressive disorders on the quality of life during acute treatment period.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3

    Topics: Adult; Benzodiazepines; Depressive Disorder, Major; Drug Administration Schedule; Drug Combinations; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Sleep Wake Disorders; Somatoform Disorders; Thiophenes

2014

Other Studies

33 other study(ies) available for fluoxetine and thiophenes

ArticleYear
5-HT1A receptor blockade increases penile erections induced by indirect serotonin agonists.
    Neuroreport, 1993, Dec-13, Volume: 5, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Drug Synergism; Fenfluramine; Fluoxetine; Labetalol; Male; Penile Erection; Piperazines; Propanolamines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1993
Antidepressant drugs given repeatedly change the binding of the dopamine D2 receptor agonist, [3H]N-0437, to dopamine D2 receptors in the rat brain.
    European journal of pharmacology, 1996, May-23, Volume: 304, Issue:1-3

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Corpus Striatum; Dopamine Agonists; Fluoxetine; Imipramine; Limbic System; Male; Mianserin; Protein Binding; Rats; Rats, Wistar; Receptors, Dopamine D2; Synaptic Membranes; Tetrahydronaphthalenes; Thiophenes; Up-Regulation

1996
Buspirone enhances duloxetine- and fluoxetine-induced increases in dialysate levels of dopamine and noradrenaline, but not serotonin, in the frontal cortex of freely moving rats.
    Journal of neurochemistry, 1997, Volume: 68, Issue:3

    Topics: Animals; Buspirone; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Microdialysis; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Thiophenes

1997
Electrophysiological effects of fluoxetine and duloxetine in the dorsal raphe nucleus and hippocampus.
    European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1

    Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Electrophysiology; Fluoxetine; Hippocampus; Infusions, Intravenous; Iontophoresis; Male; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Thiophenes

1997
Alpha2-adrenergic receptor blockade markedly potentiates duloxetine- and fluoxetine-induced increases in noradrenaline, dopamine, and serotonin levels in the frontal cortex of freely moving rats.
    Journal of neurochemistry, 1997, Volume: 69, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Biogenic Monoamines; Dopamine; Duloxetine Hydrochloride; Fluoxetine; Frontal Lobe; Male; Norepinephrine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes

1997
Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test.
    Psychopharmacology, 1998, Volume: 136, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Cyclopropanes; Desipramine; Duloxetine Hydrochloride; Fluoxetine; Male; Milnacipran; Motor Activity; Rats; Rats, Sprague-Dawley; Thiophenes

1998
Cellular electrophysiological effects of chronic fluoxetine and duloxetine administration on serotonergic responses in the aging hippocampus.
    Synapse (New York, N.Y.), 1998, Volume: 30, Issue:3

    Topics: Aging; Animals; Antidepressive Agents; Drug Administration Schedule; Duloxetine Hydrochloride; Electrophysiology; Evoked Potentials; Female; Fluoxetine; Hippocampus; Pyramidal Cells; Rats; Rats, Inbred F344; Serotonin; Thiophenes

1998
Comparison of the effects of serotonin selective, norepinephrine selective, and dual serotonin and norepinephrine reuptake inhibitors on lower urinary tract function in cats.
    Life sciences, 2002, Aug-02, Volume: 71, Issue:11

    Topics: Acetic Acid; Administration, Intravesical; Adrenergic Uptake Inhibitors; Animals; Cats; Cyclohexanols; Duloxetine Hydrochloride; Electromyography; Female; Fluoxetine; Humans; Methiothepin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiophenes; Urethra; Urinary Bladder; Venlafaxine Hydrochloride

2002
Effects of 5-HT(6) receptor blockade on the neurochemical outcome of antidepressant treatment in the frontal cortex of the rat.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Desipramine; Drug Synergism; Extracellular Space; Fluoxetine; Glutamic Acid; Male; Microdialysis; Neurons; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sulfonamides; Synaptic Transmission; Thiophenes; Venlafaxine Hydrochloride

2003
Efficacy of duloxetine, a potent and balanced serotonin-norepinephrine reuptake inhibitor in persistent pain models in rats.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2

    Topics: Acute Disease; Amines; Amitriptyline; Animals; Conscious Sedation; Cyclohexanecarboxylic Acids; Cyclohexanols; Cyclopropanes; Disease Models, Animal; Drug Therapy, Combination; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Male; Methyltyrosines; Milnacipran; Neuromuscular Junction; Norepinephrine; p-Chloroamphetamine; Pain; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Thiophenes; Venlafaxine Hydrochloride

2004
Successful treatment with duloxetine in a case of treatment refractory bulimia nervosa: a case report.
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents; Bulimia; Drug Resistance; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Thiophenes

2006
Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: evidence for synergism between serotonergic and noradrenergic reuptake inhibition.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistry; Carrageenan; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Duloxetine Hydrochloride; Edema; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Norepinephrine; Paroxetine; Pressure; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Thiophenes; Venlafaxine Hydrochloride

2006
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Extinction, Psychological; Fluoxetine; Flupenthixol; Grooming; Hydrocortisone; Injections, Intravenous; Norepinephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-2; Saimiri; Saliva; Self Administration; Thiophenes

2007
Simple options for improving signal detection in antidepressant clinical trials.
    Psychopharmacology bulletin, 2007, Volume: 40, Issue:2

    Topics: Antidepressive Agents; Citalopram; Clinical Trials as Topic; Databases, Factual; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Duloxetine Hydrochloride; Fluoxetine; Likelihood Functions; Models, Statistical; Paroxetine; Personality Inventory; Placebo Effect; Psychometrics; Reproducibility of Results; Research Design; Signal Detection, Psychological; Thiophenes; Treatment Outcome

2007
Antidepressant-induced sweating alleviated by aripiprazole.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6

    Topics: Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Dopamine Agonists; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Hyperhidrosis; Middle Aged; Piperazines; Quinolones; Sweating; Thiophenes

2008
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats.
    Neuropharmacology, 2010, Volume: 58, Issue:2

    Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Celecoxib; Central Nervous System Agents; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Escape Reaction; Fluoxetine; Inflammation; Male; Motor Activity; Neuropsychological Tests; Pain; Pain Measurement; Physical Stimulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Scopolamine; Sulfonamides; Thiophenes; Treatment Outcome

2010
Antidepressant-like effects of an AMPA receptor potentiator under a chronic mild stress paradigm.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:9

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Benzodiazepines; Chronic Disease; Depression; Depressive Disorder; Disease Models, Animal; Emotions; Fluoxetine; Hindlimb Suspension; Male; Mice; Mice, Inbred BALB C; Motor Activity; Receptors, AMPA; Stress, Psychological; Sulfonamides; Thiophenes

2010
Serotonin syndrome in an octogenarian after switch from fluoxetine to duloxetine.
    Journal of the American Geriatrics Society, 2009, Volume: 57, Issue:12

    Topics: Aged, 80 and over; Duloxetine Hydrochloride; Fluoxetine; Humans; Male; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Thiophenes

2009
Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice.
    Brain research, 2010, Jun-23, Volume: 1341

    Topics: Animals; Behavior, Animal; Cell Proliferation; Cell Survival; Duloxetine Hydrochloride; Female; Fluoxetine; Hippocampus; Mice; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Neuronal Plasticity; Neurons; Physical Conditioning, Animal; Selective Serotonin Reuptake Inhibitors; Thiophenes

2010
Rapid HPLC method for the simultaneous monitoring of duloxetine, venlaflaxine, fluoxetine and paroxetine in biofluids.
    Bioanalysis, 2009, Volume: 1, Issue:5

    Topics: Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Humans; Limit of Detection; Paroxetine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Thiophenes; Venlafaxine Hydrochloride

2009
Gap junction dysfunction in the prefrontal cortex induces depressive-like behaviors in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:5

    Topics: Analysis of Variance; Animals; Carbenoxolone; Connexin 43; Disease Models, Animal; Duloxetine Hydrochloride; Electroshock; Exploratory Behavior; Fluoxetine; Food Deprivation; Food Preferences; Gap Junctions; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hormone Antagonists; Inhibition, Psychological; Isoquinolines; Male; Microscopy, Electron, Transmission; Mifepristone; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Thiophenes

2012
A simple HPLC method for the simultaneous determination of two selective serotonin reuptake inhibitors and two serotonin-norepinephrine reuptake inhibitors in hair, nail clippings, and cerebrospinal fluid.
    Journal of separation science, 2012, Volume: 35, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Biological Transport; Cerebrospinal Fluid; Chromatography, High Pressure Liquid; Cyclohexanols; Duloxetine Hydrochloride; Fluoxetine; Hair; Humans; Nails; Norepinephrine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Venlafaxine Hydrochloride

2012
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water

2012
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection

2013
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes

2013
Copper(II)-catalyzed enantioselective hydrosilylation of halo-substituted alkyl aryl and heteroaryl ketones: asymmetric synthesis of (R)-fluoxetine and (S)-duloxetine.
    Organic & biomolecular chemistry, 2014, Feb-14, Volume: 12, Issue:6

    Topics: Catalysis; Copper; Duloxetine Hydrochloride; Fluoxetine; Ketones; Molecular Conformation; Organometallic Compounds; Stereoisomerism; Thiophenes

2014
Total synthesis of fluoxetine and duloxetine through an in situ imine formation/borylation/transimination and reduction approach.
    Organic & biomolecular chemistry, 2014, Aug-28, Volume: 12, Issue:32

    Topics: Chemistry, Organic; Duloxetine Hydrochloride; Fluoxetine; Imines; Thiophenes

2014
Copper-catalysed selective hydroamination reactions of alkynes.
    Nature chemistry, 2015, Volume: 7, Issue:1

    Topics: Alkynes; Amination; Amines; Atomoxetine Hydrochloride; Benzhydryl Compounds; Catalysis; Copper; Cresols; Duloxetine Hydrochloride; Fluoxetine; Phenylpropanolamine; Propylamines; Stereoisomerism; Thiophenes; Tolterodine Tartrate

2015
ZnCl2 -promoted asymmetric hydrogenation of β-secondary-amino ketones catalyzed by a P-chiral Rh-bisphosphine complex.
    Angewandte Chemie (International ed. in English), 2015, Feb-09, Volume: 54, Issue:7

    Topics: Amination; Amino Alcohols; Atomoxetine Hydrochloride; Catalysis; Chlorides; Coordination Complexes; Duloxetine Hydrochloride; Fluoxetine; Hydrogenation; Ketones; Phosphines; Propylamines; Rhodium; Stereoisomerism; Thiophenes; Zinc Compounds

2015
Antidepressant effects of combination of brexpiprazole and fluoxetine on depression-like behavior and dendritic changes in mice after inflammation.
    Psychopharmacology, 2017, Volume: 234, Issue:4

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dendritic Spines; Depression; Fluoxetine; Inflammation; Male; Mice; Neurons; Prefrontal Cortex; Quinolones; Signal Transduction; Thiophenes

2017
Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling.
    Scientific reports, 2016, 12-19, Volume: 6

    Topics: Animals; Antidepressive Agents; Azepines; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Dendritic Spines; Depressive Disorder, Major; Disease Models, Animal; Drug Therapy, Combination; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Phenotype; Quinolones; Receptor, trkB; Selective Serotonin Reuptake Inhibitors; Signal Transduction; Thiophenes

2016
Alterations in amino acid levels in mouse brain regions after adjunctive treatment of brexpiprazole with fluoxetine: comparison with (R)-ketamine.
    Psychopharmacology, 2017, Volume: 234, Issue:21

    Topics: Administration, Oral; Amino Acids; Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Fluoxetine; Ketamine; Male; Mice; Mice, Inbred C57BL; Quinolones; Receptors, N-Methyl-D-Aspartate; Thiophenes

2017
Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:7

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Body Temperature; Central Nervous System Sensitization; Female; Fluoxetine; Indoles; Male; Mice; Mice, Knockout; Mice, Transgenic; Neurogenesis; Prepulse Inhibition; Raphe Nuclei; Receptor, Serotonin, 5-HT2B; Serotonergic Neurons; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Transcription Factors

2018