fluoxetine and s20098

fluoxetine has been researched along with s20098 in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (14.29)29.6817
2010's16 (76.19)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ang, W; Chang, Y; Li, C; Liu, Y; Luo, Y; Pi, W; Xiong, L; Yang, T; Zheng, J1
Ang, W; Chang, Y; Chen, G; Deng, Y; Li, C; Liu, Y; Luo, Y; Pi, W; Wei, Y; Xiong, L; Yang, B; Yang, S; Zheng, J; Zhou, L1
Chen, JJ; Geng, CA; Huang, XY; Li, TZ; Ma, YB; Yan, DX; Yang, TH; Zhang, XM1
Chen, JJ; Geng, CA; Hu, J; Huang, XY; Li, TZ; Liu, SB; Sun, JJ; Zhang, XM1
Boyer, PA; Hamon, M; Hanoun, N; Lanfumey, L; Mocaër, E1
Barden, N; Gabriel, C; Hamon, M; Lanfumey, L; Lelievre, V; Melfort, M; Mocaër, E; Païzanis, E; Renoir, T; Saurini, F1
Rohmer, JG1
Corral, RM; Gentil, V; Hale, A; Mencacci, C; Ruiz, JS; Severo, CA1
David, DJ; Enhamre, E; Gabriel, C; Gardier, AM; Guilloux, JP; Hen, R; Mocaër, E; Rainer, Q; Xia, L1
Dubois, M; El Yacoubi, M; Gabriel, C; Mocaër, E; Vaugeois, JM1
Kalamkar, AM; Mangaonkar, KV; Nerurkar, KK; Patil, SR; Pingale, SG; Pukale, V1
Girbig, D; Igl, BW; Lehmann, T; Obendorf, M; Patchev, VK; Prelle, K1
Humpston, CS; Robinson, ES; Wood, CM1
Corruble, E; Demyttenaere, K; Hale, A; Kasper, S; Picarel-Blanchot, F; Quera-Salva, MA1
Corbach-Söhle, S; Flügge, G; Fuchs, E; Kohlhause, S; Schlumbohm, C; Schmelting, B1
Crutel, VS; Fones Soon Leng, C; Huang, YS; Kim, YS; Shu, L; Sulaiman, AH1
Almeida, OF; Alves, ND; Beckers, J; Bessa, JM; Correia, JS; Irmler, M; Korostynski, M; Machado-Santos, AR; Mateus-Pinheiro, A; Morais, M; Patrício, P; Piechota, M; Pinto, L; Sousa, N; Stoffel, R1
Bhatia, MS; Gupta, K; Gupta, LK; Gupta, R; Tripathi, AK1
Cui, P; Hao, L; He, X; Jia, Y; Liang, Z; Tong, B; Yang, F; Yuan, J; Zhao, L; Zhu, R1

Trials

5 trial(s) available for fluoxetine and s20098

ArticleYear
Superior antidepressant efficacy results of agomelatine versus fluoxetine in severe MDD patients: a randomized, double-blind study.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:6

    Topics: Acetamides; Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Female; Fluoxetine; Humans; Internationality; Male; Middle Aged; Patient Dropouts; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Severity of Illness Index; Young Adult

2010
Validated LC-MS/MS method for quantification of agomelatine in human plasma and its application in a pharmacokinetic study.
    Journal of mass spectrometry : JMS, 2012, Volume: 47, Issue:1

    Topics: Acetamides; Area Under Curve; Chromatography, Liquid; Fluoxetine; Humans; Least-Squares Analysis; Liquid-Liquid Extraction; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2012
Comparable efficacy and safety of 8 weeks treatment with agomelatine 25-50mg or fluoxetine 20-40mg in Asian out-patients with major depressive disorder.
    Asian journal of psychiatry, 2014, Volume: 8

    Topics: Acetamides; Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult

2014
Effect of Agomelatine and Fluoxetine on HAM-D Score, Serum Brain-Derived Neurotrophic Factor, and Tumor Necrosis Factor-α Level in Patients With Major Depressive Disorder With Severe Depression.
    Journal of clinical pharmacology, 2017, Volume: 57, Issue:12

    Topics: Acetamides; Adult; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depressive Disorder, Major; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Male; Middle Aged; Psychiatric Status Rating Scales; Tumor Necrosis Factor-alpha

2017
Agomelatine might be more appropriate for elderly, depressed, type 2 diabetes mellitus patients than paroxetine/fluoxetine.
    Aging, 2021, 10-05, Volume: 13, Issue:19

    Topics: Acetamides; Adult; Aged; Aging; Antidepressive Agents, Second-Generation; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Male; Middle Aged; Paroxetine

2021

Other Studies

16 other study(ies) available for fluoxetine and s20098

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and evaluation of amide side-chain modified Agomelatine analogues as potential antidepressant-like agents.
    Bioorganic & medicinal chemistry letters, 2014, Apr-01, Volume: 24, Issue:7

    Topics: Acetamides; Amides; Animals; Antidepressive Agents; Behavior, Animal; Cell Line; Cell Survival; Corticosterone; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Molecular Structure; PC12 Cells; Rats; Structure-Activity Relationship; Swimming

2014
Synthesis and biological evaluation of novel naphthalene compounds as potential antidepressant agents.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Cell Line; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Motor Activity; Naphthalenes; PC12 Cells; Rats; Structure-Activity Relationship; Swimming

2014
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Animals; Antidepressive Agents; Biphenyl Compounds; Brain; Depression; Female; HEK293 Cells; Hindlimb Suspension; Humans; Lignans; Male; Mice; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2

2018
Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities.
    RSC medicinal chemistry, 2022, Oct-19, Volume: 13, Issue:10

    Topics:

2022
Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain.
    Neuropharmacology, 2004, Volume: 47, Issue:4

    Topics: Acetamides; Action Potentials; Animals; Antidepressive Agents; Brain; Dose-Response Relationship, Drug; Fluoxetine; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Antagonists

2004
Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:6

    Topics: Acetamides; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cell Death; Cell Proliferation; Doublecortin Domain Proteins; Drug Administration Schedule; Fluoxetine; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hindlimb Suspension; Hippocampus; In Situ Nick-End Labeling; Male; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neuronal Plasticity; Neuropeptides; Rats; Receptors, Glucocorticoid; RNA, Messenger

2010
[Further evidence of the efficacy of the antidepressant Valdoxan (agomelatine) compared with conventional antidepressive drugs (from the ECNP held in Istanbul, 15 September 2009)].
    L'Encephale, 2009, Volume: 35, Issue:6

    Topics: Acetamides; Antidepressive Agents; Depressive Disorder, Major; Dose-Response Relationship, Drug; Fluoxetine; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2009
Agomelatine: new drug. Adverse effects and no proven efficacy.
    Prescrire international, 2009, Volume: 18, Issue:104

    Topics: Acetamides; Animals; Antidepressive Agents; Bias; Carcinogens; Clinical Trials as Topic; Cyclohexanols; Depression; Depressive Disorder; Double-Blind Method; Drug Approval; Europe; Fluoxetine; Humans; Hypnotics and Sedatives; Melatonin; Paroxetine; Psychiatric Status Rating Scales; Receptors, Melatonin; Recurrence; Selective Serotonin Reuptake Inhibitors; Suicide; Treatment Outcome; Venlafaxine Hydrochloride

2009
Beneficial behavioural and neurogenic effects of agomelatine in a model of depression/anxiety.
    The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:3

    Topics: Acetamides; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Cell Proliferation; Circadian Rhythm; Corticosterone; Dendrites; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Male; Mice, Inbred C57BL; Motor Activity; Neurogenesis; Neurons; Serotonin 5-HT2 Receptor Antagonists

2012
Chronic agomelatine and fluoxetine induce antidepressant-like effects in H/Rouen mice, a genetic mouse model of depression.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 100, Issue:2

    Topics: Acetamides; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Fluoxetine; Locomotion; Mice

2011
Endpoints of drug discovery for menopausal vasomotor symptoms: interpretation of data from a proxy of disease.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:8

    Topics: Acetamides; Amines; Animals; Body Temperature Regulation; Cyclohexanecarboxylic Acids; Cyclohexanols; Disease Models, Animal; Diurnal Enuresis; Drug Discovery; Estradiol; Female; Fluoxetine; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Hypnotics and Sedatives; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Skin Temperature; Venlafaxine Hydrochloride

2012
Investigating the roles of different monoamine transmitters and impulse control using the 5-choice serial reaction time task.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:2

    Topics: Acetamides; Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Bupropion; Choice Behavior; Cyclobutanes; Cyclohexanols; Fluoxetine; Hypnotics and Sedatives; Idazoxan; Impulsive Behavior; Male; Norepinephrine; Paroxetine; Rats; Reaction Time; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2013
A pooled analysis of six month comparative efficacy and tolerability in four randomized clinical trials: agomelatine versus escitalopram, fluoxetine, and sertraline.
    CNS spectrums, 2013, Volume: 18, Issue:3

    Topics: Acetamides; Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder; Depressive Disorder, Major; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Male; Middle Aged; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Sertraline; Treatment Outcome; Young Adult

2013
Agomelatine in the tree shrew model of depression: effects on stress-induced nocturnal hyperthermia and hormonal status.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:3

    Topics: Acetamides; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Body Temperature; Body Weight; Central Nervous System Depressants; Circadian Rhythm; Depressive Disorder; Fever; Fluoxetine; Hydrocortisone; Indoles; Male; Melatonin; Motor Activity; Norepinephrine; Pyridines; Serotonin 5-HT2 Receptor Antagonists; Stress, Psychological; Tupaiidae

2014
Differential and converging molecular mechanisms of antidepressants' action in the hippocampal dentate gyrus.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:2

    Topics: Acetamides; Animals; Antidepressive Agents; Chronic Disease; Dentate Gyrus; Depressive Disorder; Disease Models, Animal; Fluoxetine; Gene Expression; Imipramine; Male; Neurons; Random Allocation; Rats, Wistar; Stress, Psychological; Thiazepines; Uncertainty

2015