fluoxetine and piperidines

fluoxetine has been researched along with piperidines in 94 studies

Research

Studies (94)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (15.96)	18.7374
1990's	24 (25.53)	18.2507
2000's	28 (29.79)	29.6817
2010's	26 (27.66)	24.3611
2020's	1 (1.06)	2.80

Authors

Authors	Studies
Kabouche, M; Le Fur, G; Uzan, A	1
Block, P; Fieve, RR; Peselow, ED; Robins, CJ; Sanfilipo, MP	1
Artigas, F; Ortiz, J	1
Difiglia, C; Fieve, RR; Peselow, ED; Sanfilipo, MP	1
DeVane, CL	1
Johnson, AM; Tulloch, IF	1
Goodman, WK; McDougle, CJ; Price, LH	1
Anderer, P; Frey, R; Grünberger, J; Krupka, M; Saletu, B; See, WR	1
Baldwin, D; Bullock, T; Montgomery, D; Montgomery, S	1
Netter, P; Rammsayer, T	3
Koe, BK; Lebel, LA; Welch, WM	1
Cool, DR; Ganapathy, V; Liebach, FH	1
Rickels, K; Schweizer, E	1
Westwick, F	1
Kleven, MS; Sparber, SB	1
Esnaud, H; Graham, D; Habert, E; Langer, SZ	1
Bethea, CL; Richardson, KD; Urban, JH; Van de Kar, LD	1
Fuller, RW	1
Asberg, M; Eriksson, B; Mårtensson, B; Träskman-Bendz, L; Wägner, A	1
Smith, DF	1
Lin, MT; Tsai, ML	1
Bergström, M; Eriksson, K; Marcusson, JO; Ross, SB	1
Broadhurst, AM; Wood, MD; Wyllie, MG	1
Richardson, KD; Urban, JH; Van de Kar, LD	1
Angel, I; Claustre, Y; Langer, SZ; Scatton, B; Taranger, MA	1
Bosin, TR; Mais, DE	1
Giakas, WJ	1
Hyttel, J; Sánchez, C	1
Katz, RJ; Rosenthal, M	1
Fallon, BA; Feerick, J; Liebowitz, MR; Marshall, RD; Schneier, FR	1
Holtzman, SG; Steinfels, GF	1
Angel, I; Garreau, M; Langer, SZ; Prouteau, M; Schoemaker, H	1
Earley, B; Faherty, CJ; Leonard, BE	1
Ashby, CR; Katsumori, H; Minabe, Y; Watanabe, K	1
Jorgensen, H; Kjaer, A; Knigge, U; Møller, M; Søe-Jensen, P; Warberg, J	1
Baiardi, P; Lucchelli, A; Masoero, E; Santagostino-Barbone, MG; Tonini, M	1
Malone, DT; Taylor, DA	1
Hatanaka, K; Yamaguchi, T; Yatsugi, S	2
Carlson, EC; de Felipe, C; Harrison, T; Hunt, S; Oates, B; Owen, S; Rupniak, NM; Seward, E; Wheeldon, A	1
Branchek, TA; Calligaro, DO; Czachura, JF; Dreshfield-Ahmad, LJ; Evans, DC; Hemrick-Luecke, SK; Kallman, MJ; Kendrick, WT; Leander, JD; Nelson, DL; Overshiner, CD; Rasmussen, K; Wainscott, DB; Wolff, MC; Wong, DT; Xu, YC; Zgombick, JM	1
Ballard, TM; Higgins, GA; Sänger, S	1
Cecil, A; Crites, G; Goldenberg, R; Knapp, RJ; Malatynska, E; Miller, C; Shuck, C; Watkins, J	1
Garrido Barral, A; González Moneo, MJ	1
Kaur, G; Kulkarni, SK	1
Fantegrossi, WE; Godlewski, T; Karabenick, RL; Rice, KC; Stephens, JM; Ullrich, T; Woods, JH	1
Arban, R; Bettelini, L; Corsi, M; Gerrard, PA; Griffante, C; Marchi, M; Varnier, G; Zanetti, L; Zocchi, A	1
Cortizo, L; García, N; Innerárity, A; Labeaga, L; Mosquera, R; Orjales, A; Pumar, MC; Toledo, A	1
Boot, JR; Broadmore, RJ; Cooper, J; Eyre, TA; Mitchell, SN; Pullar, IA; Sanger, GJ; Wedley, S	1
Gower, AJ; Lamberty, Y	1
Griebel, G; Scatton, B; Stemmelin, J	1
Biba, A; Christodoulou, A; Chrysikakou, S; Giannou, H; Kontis, D; Maillis, A; Pallidi, S; Rabavilas, A; Tsaltas, E	1
Abo, A; Artigas, F; Marek, GJ; Martin-Ruiz, R	1
Artaiz, I; Castro, E; Del Olmo, E; Díaz, A; Innerárity, A; Labeaga, L; Orjales, A; Pazos, A; Pena, R; Ruiz-Ortega, JA; Zazpe, A	1
Carboni, L; Castelletti, L; Domenici, E; Milli, A; Piubelli, C; Vighini, M	1
Anderson, CL; Anson, BD; Delisle, BP; Eckhardt, LL; Gillman, BM; Holzem, KM; January, CT; Klemens, CA; Makielski, JC; Rajamani, S; Valdivia, CR	1
de Boissezon, X; de Boysson, C; Démonet, JF; Peran, P	1
Ben-Shabat, S; Fride, E; Gobshtis, N	1
Gross, G; Groth, I; Jongen-Relo, A; Rex, A; Wicke, KM	1
Banti, I; Betti, L; Demontis, GC; Lapucci, A; Mazzoni, MR; Nencetti, S; Rossello, A	1
Al-Zaman, Y; Aylwin, S	1
Cai, L; Hertz, L; Li, B; Nu, W; Peng, L; Zhang, H; Zhang, S	1
Bouchez, G; Brocco, M; Dekeyne, A; Di Cara, B; Gannon, RL; Gobert, A; Lejeune, F; Millan, MJ	1
Cajina, M; Craig, DA; Gerald, CP; Kong, R; Marsteller, DA; Swanson, CJ	1
Ciccocioppo, R; Cifani, C; Di Francesco, C; Massi, M; Melotto, S; Righetti, C; Tessari, M; Zanoncelli, A	1
Abou-Gharbia, MA; Adedoyin, A; Andree, TH; Aschmies, SH; Asselin, M; Bach, AC; Beyer, C; Bicksler, JJ; Childers, WE; Chong, DC; Comery, TA; Day, M; Grauer, SM; Grosu, GT; Harrison, BL; Havran, LM; Hirst, WD; Hughes, ZA; Huselton, C; Kagan, N; Kleintop, T; Magolda, R; Marathias, V; Platt, B; Pulicicchio, C; Robichaud, AJ; Rosenzweig-Lipson, S; Sabb, AL; Shen, Z; Smith, DE; Sukoff-Rizzo, SJ; Sullivan, KM; Zhang, MY	1
Bianciotti, LG; Hope, SI; Nabhen, SL; Soria, C; Vatta, MS	1
Haller, J; Mikics, E; Nagy, R; Pelczer, KG; Toth, M	1
Abi-Gerges, N; Holkham, H; Jones, EM; Pollard, CE; Robertson, GA; Valentin, JP	1
Che, CT; Ip, SP; Mao, QQ; Xian, YF	1
Jain, NS; Manna, SS; Umathe, SN	1
Bruce, A; Jennings, KA; Knudsen, GM; Lesch, KP; Licht, CL; Sharp, T	1
Nayak, S; Pal, A; Sahu, PK; Swain, T	1
Howell, LL; Kimmel, HL; Murnane, KS; Rice, KC	1
Fritz, K; Marshall, K; Thom, W; Xiong, GL	1
Aigner, L; Gaburro, S; Irschick, R; Kandasamy, M; Klimaschewski, L; Landgraf, R; Sah, A; Sartori, SB; Schmuckermair, C; Singewald, N	1
Buck, NS; Davis, JJ; Greis, PE; Johnson, KB; Swenson, JD	1
Bronson, JJ; Davis, CD; Gillman, KW; Lelas, S; Li, YW; Lodge, NJ; Macor, JE; Molski, TF; Newberry, KS; Newton, AE; Parker, MF; Pieschl, RL; Taber, MT; Wallace-Boone, TL	1
Brański, P; Pałucha-Poniewiera, A; Pilc, A; Stachowicz, K; Sławińska, A; Wierońska, JM	1
Aissouni, Y; Chalus, M; Courteix, C; Dupuis, A; Eschalier, A; Hernández, A; Marin, P; Pelissier, T; Pichon, X; Privat, AM; Wattiez, AS	1
Baaré, WF; Fisher, PM; Frokjaer, VG; Haahr, ME; Jensen, CG; Knudsen, GM; Lehel, S; Madsen, K; Mahon, BM; Norremolle, A; Rabiner, EA	1
Darcet, F; David, DJ; Gardier, AM; Hen, R; Kerdine-Römer, S; Mendez-David, I; Wu, MV	1
Chew, AP; Lim, WS; Tan, KT	1
Dudka, J; Kasperek, R; Nowak, G; Poleszak, E; Serefko, A; Wlaź, A; Wlaź, P; Wośko, S; Wróbel, A	1
Chae, YJ; Choi, JS; Hahn, SJ; Jeon, JH; Kim, IB; Lee, HJ; Sung, KW	1
Darcet, F; David, DJ; Gardier, AM; Guilloux, JP	1
Oniszczuk, A; Poleszak, E; Serefko, A; Stasiuk, W; Świąder, K; Szopa, A; Wlaź, P; Wośko, S; Wyska, E	1
Gore, C; Wu, C	1
Bulik, CM; Diberto, JF; Hardaway, JA; Hwa, LS; Jensen, J; Kash, TL; Kim, M; Lowery-Gionta, EG; Mazzone, CM; Pleil, KE; Sugam, JA	1
Asth, L; Calo', G; Gavioli, EC; Guerrini, R; Holanda, VA; Medeiros, IU	1
Hu, XX; Li, YF; Liu, HX; Ran, YH; Wang, YL; Zhang, LM; Zhao, N	1
Aly, KA; Babu, M; Cayabyab, FS; Fonge, H; He, S; Islam, S; Moutaoufik, MT; Persad, A; Wu, A	1

Reviews

15 review(s) available for fluoxetine and piperidines

Article	Year
Melancholic/endogenous depression and response to somatic treatment and placebo. The American journal of psychiatry, 1992, Volume: 149, Issue:10 Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome	1992
Pharmacokinetics of the selective serotonin reuptake inhibitors. The Journal of clinical psychiatry, 1992, Volume: 53 Suppl Topics: 1-Naphthylamine; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperidines; Serotonin Antagonists; Sertraline	1992
The pharmacologic profile of paroxetine, a new selective serotonin reuptake inhibitor. The Journal of clinical psychiatry, 1992, Volume: 53 Suppl Topics: 1-Naphthylamine; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperidines; Serotonin Antagonists; Sertraline	1992
Pharmacotherapy of obsessive compulsive disorder. The Journal of clinical psychiatry, 1992, Volume: 53 Suppl Topics: 1-Naphthylamine; Antidepressive Agents; Clomipramine; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Paroxetine; Piperidines; Serotonin; Sertraline	1992
5-HT reuptake inhibitors, tricyclic antidepressants and suicidal behaviour. International clinical psychopharmacology, 1991, Volume: 6 Suppl 3 Topics: Antidepressive Agents; Depressive Disorder; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Humans; Mianserin; Paroxetine; Piperidines; Serotonin Antagonists; Suicide; Suicide Prevention	1991
Clinical overview of serotonin reuptake inhibitors. The Journal of clinical psychiatry, 1990, Volume: 51 Suppl B Topics: 1-Naphthylamine; Antidepressive Agents, Tricyclic; Depressive Disorder; Fluoxetine; Humans; Paroxetine; Piperidines; Serotonin Antagonists; Sertraline; Zimeldine	1990
Depression and selective serotonin reuptake inhibitors. British journal of hospital medicine, 1990, Volume: 44, Issue:5 Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Fluoxetine; Humans; Imipramine; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Paroxetine; Piperidines; Serotonin Antagonists	1990
Biochemical pharmacology of the serotonin system. Advances in neurology, 1986, Volume: 43 Topics: Alanine; Brain; Citalopram; Clomipramine; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Monoamine Oxidase Inhibitors; Neurons; Oximes; p-Chloroamphetamine; Paroxetine; Piperidines; Propylamines; Receptors, Serotonin; Reserpine; Serotonin; Serotonin Antagonists; Synapses; Tetrabenazine; Zimeldine	1986
Therapeutic effects of serotonin uptake inhibitors in depression. The Journal of clinical psychiatry, 1986, Volume: 47 Suppl Topics: 5-Hydroxytryptophan; Alanine; Citalopram; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Propylamines; Serotonin; Serotonin Antagonists; Trazodone; Zimeldine	1986
Medication therapy for social phobia. The Journal of clinical psychiatry, 1994, Volume: 55 Suppl Topics: Benzamides; Benzodiazepines; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Fluoxetine; Humans; Moclobemide; Monoamine Oxidase Inhibitors; Phenelzine; Phobic Disorders; Piperidines; Selective Serotonin Reuptake Inhibitors; Treatment Outcome	1994
[Latest therapies for treating dementia]. Atencion primaria, 2002, May-15, Volume: 29, Issue:8 Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clinical Trials as Topic; Cognition; Cohort Studies; Controlled Clinical Trials as Topic; Dementia, Vascular; Donepezil; Female; Fluoxetine; Galantamine; Haloperidol; Hormone Replacement Therapy; Humans; Hydroxychloroquine; Indans; Middle Aged; Nootropic Agents; Piperidines; Placebos; Practice Guidelines as Topic; Quality of Life; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Trazodone	2002
Pharmacotherapy of aphasia: myth or reality? Brain and language, 2007, Volume: 102, Issue:1 Topics: Amphetamine; Aphasia; Bromocriptine; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Dopamine Agents; Fluoxetine; GABA Agonists; Humans; Indans; Neuroprotective Agents; Paroxetine; Physostigmine; Piperidines; Piracetam; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Stroke; Zolpidem	2007
Emerging concepts in the medical and surgical treatment of obesity. Frontiers of hormone research, 2008, Volume: 36 Topics: Adipose Tissue; Amyloid; Anticonvulsants; Antidepressive Agents; Anxiety; Appetite Regulation; Bariatric Surgery; Body Mass Index; Bupropion; Cholecystokinin; Ciliary Neurotrophic Factor; Clinical Trials as Topic; Cyclobutanes; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Fructose; Ghrelin; Humans; Intra-Abdominal Fat; Islet Amyloid Polypeptide; Isoxazoles; Lactones; Leptin; Metabolic Syndrome; Metformin; Obesity; Obesity, Morbid; Orlistat; Oxyntomodulin; Peptide YY; Piperidines; Polycystic Ovary Syndrome; Pyrazoles; Rimonabant; Sertraline; Sleep Apnea, Obstructive; Surgical Procedures, Operative; Topiramate; Zonisamide	2008
Medical Therapies of Amblyopia: Translational Research to Expand Our Treatment Armamentarium. Seminars in ophthalmology, 2016, Volume: 31, Issue:1-2 Topics: Amblyopia; Carbidopa; Cholinesterase Inhibitors; Donepezil; Dopamine Agonists; Drug Combinations; Fluoxetine; Humans; Indans; Levodopa; Neuronal Plasticity; Piperidines; Selective Serotonin Reuptake Inhibitors; Translational Research, Biomedical; Visual Cortex	2016
HERG channel and cancer: A mechanistic review of carcinogenic processes and therapeutic potential. Biochimica et biophysica acta. Reviews on cancer, 2020, Volume: 1873, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Carcinogenesis; Cell Movement; Cell Proliferation; Epigenesis, Genetic; ERG1 Potassium Channel; Fluoxetine; Gene Expression Regulation, Neoplastic; Humans; Integrin beta1; Long QT Syndrome; Membrane Potentials; Molecular Docking Simulation; Mutation; Myocytes, Cardiac; Neoplasms; Piperidines; Protein Conformation, alpha-Helical; Protein Interaction Mapping; Protein Structure, Quaternary; Pyridines; Signal Transduction; STAT1 Transcription Factor; Sulfanilamides	2020

Trials

6 trial(s) available for fluoxetine and piperidines

Article	Year
Sociotropy and autonomy: relationship to antidepressant drug treatment response and endogenous-nonendogenous dichotomy. Journal of abnormal psychology, 1992, Volume: 101, Issue:3 Topics: Adult; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Fluoxetine; Humans; Imipramine; Individuality; Internal-External Control; Interpersonal Relations; Male; Oximes; Paroxetine; Piperidines; Serotonin Antagonists	1992
Melancholic/endogenous depression and response to somatic treatment and placebo. The American journal of psychiatry, 1992, Volume: 149, Issue:10 Topics: Antidepressive Agents; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Imipramine; Oximes; Paroxetine; Piperidines; Placebos; Prospective Studies; Psychiatric Status Rating Scales; Treatment Outcome	1992
Sleep laboratory studies on the single-dose effects of serotonin reuptake inhibitors paroxetine and fluoxetine on human sleep and awakening qualities. Sleep, 1991, Volume: 14, Issue:5 Topics: Adult; Arousal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electroencephalography; Female; Fluoxetine; Humans; Male; Middle Aged; Monitoring, Physiologic; Paroxetine; Piperidines; Serotonin Antagonists; Sleep Stages; Wakefulness	1991
Serotoninergic effects on sensory and motor responses in extraverts and introverts. International clinical psychopharmacology, 1989, Volume: 4 Suppl 1 Topics: Adult; Arousal; Extraversion, Psychological; Flicker Fusion; Fluoxetine; Humans; Introversion, Psychological; Male; Piperidines; Psychomotor Performance; Reaction Time; Ritanserin; Serotonin	1989
Effects of changes in brain 5-HT activity on indicators of cortical arousal. International clinical psychopharmacology, 1988, Volume: 3, Issue:3 Topics: Adult; Arousal; Attention; Cerebral Cortex; Double-Blind Method; Fluoxetine; Humans; Male; Piperidines; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists	1988
Central 5-HT4 receptor binding as biomarker of serotonergic tonus in humans: a [11C]SB207145 PET study. Molecular psychiatry, 2014, Volume: 19, Issue:4 Topics: Adult; Brain; Carbon Radioisotopes; Double-Blind Method; Fluoxetine; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male; Piperidines; Positron-Emission Tomography; Protein Binding; Receptors, Serotonin, 5-HT4; Selective Serotonin Reuptake Inhibitors; Young Adult	2014

Other Studies

74 other study(ies) available for fluoxetine and piperidines

Article	Year
On the regional and specific serotonin uptake inhibition by LM 5008. Life sciences, 1978, Nov-09, Volume: 23, Issue:19 Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Dopamine; Female; Fluoxetine; In Vitro Techniques; Indoles; Male; Norepinephrine; Parasympatholytics; Piperidines; Rabbits; Rats; Receptors, Muscarinic; Saimiri; Serotonin; Synaptosomes	1978
Effects of monoamine uptake inhibitors on extracellular and platelet 5-hydroxytryptamine in rat blood: different effects of clomipramine and fluoxetine. British journal of pharmacology, 1992, Volume: 105, Issue:4 Topics: Animals; Biological Transport, Active; Blood Platelets; Clomipramine; Endothelium, Vascular; Fluoxetine; Lung; Male; Paroxetine; Piperidines; Plasma; Rats; Rats, Inbred Strains; Serotonin	1992
Personality related differences in response to 5-HT uptake inhibition. The International journal of neuroscience, 1990, Volume: 55, Issue:2-4 Topics: Adult; Analysis of Variance; Choice Behavior; Double-Blind Method; Emotions; Flicker Fusion; Fluoxetine; Humans; Male; Personality; Piperidines; Reaction Time; Reference Values; Ritanserin; Serotonin Antagonists	1990
[3H] sertraline binding to rat brain membranes. Psychopharmacology, 1990, Volume: 100, Issue:4 Topics: 1-Naphthylamine; Animals; Brain; Fenclonine; Fluoxetine; Imipramine; In Vitro Techniques; Male; Membranes; Naphthalenes; Paroxetine; Piperidines; Rats; Receptors, Serotonin; Serotonin Antagonists; Sertraline	1990
Interaction of fluoxetine with the human placental serotonin transporter. Biochemical pharmacology, 1990, Nov-01, Volume: 40, Issue:9 Topics: Carrier Proteins; Female; Fluoxetine; Humans; In Vitro Techniques; Microvilli; Paroxetine; Piperidines; Placenta; Pregnancy; Serotonin; Serotonin Antagonists	1990
Modification of quasi-morphine withdrawal with serotonin agonists and antagonists: evidence for a role of serotonin in the expression of opiate withdrawal. Psychopharmacology, 1989, Volume: 98, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 5-Hydroxytryptophan; Animals; Fluoxetine; Male; Methysergide; Mianserin; Morphine; Piperidines; Rats; Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome	1989
A common binding site for tricyclic and nontricyclic 5-hydroxytryptamine uptake inhibitors at the substrate recognition site of the neuronal sodium-dependent 5-hydroxytryptamine transporter. Biochemical pharmacology, 1989, Nov-01, Volume: 38, Issue:21 Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Binding, Competitive; Biological Transport; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Ethylmaleimide; Fluoxetine; Imipramine; Male; Neurons; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sodium	1989
Pharmacological studies on the serotoninergic and nonserotonin-mediated stimulation of prolactin and corticosterone secretion by fenfluramine. Effects of pretreatment with fluoxetine, indalpine, PCPA, and L-tryptophan. Neuroendocrinology, 1985, Volume: 41, Issue:4 Topics: Animals; Antidepressive Agents; Corticosterone; Fenclonine; Fenfluramine; Fluoxetine; Kinetics; Male; Piperidines; Prolactin; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1985
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake area. Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1 Topics: Alanine; Amphetamine; Aniline Compounds; Animals; Antidepressive Agents; Blood Platelets; Brain; Fluoxetine; Humans; Male; Methadone; Mianserin; Mirtazapine; Morpholines; Naphthalenes; Nefopam; Nomifensine; Paroxetine; Piperidines; Rabbits; Serotonin; Stereoisomerism; Tranylcypromine; Viloxazine; Zimeldine	1986
Hypertension and tachycardia produced by inhibition of reuptake of 5-hydroxytryptamine by fluoxetine in the rat. Neuropharmacology, 1986, Volume: 25, Issue:7 Topics: Adrenalectomy; Animals; Blood Pressure; Brain; Female; Fluoxetine; Heart Rate; Injections, Intraventricular; Ketanserin; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Vagotomy	1986
Characterization of [3H]paroxetine binding in rat brain. Journal of neurochemistry, 1988, Volume: 50, Issue:6 Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Cerebral Cortex; Citalopram; Fluoxetine; Imipramine; Male; Paroxetine; Peptide Hydrolases; Piperidines; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tritium	1988
Examination of the relationship between the uptake system for 5-hydroxytryptamine and the high-affinity [3H]imipramine binding site--I. Inhibition by drugs. Neuropharmacology, 1986, Volume: 25, Issue:5 Topics: Animals; Carrier Proteins; Catecholamines; Cerebral Cortex; Energy Metabolism; Fluoxetine; Imipramine; In Vitro Techniques; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Synaptosomes; Zimeldine	1986
Serotonin and norepinephrine-dependent effects of fenfluramine on plasma renin activity in conscious male rats. Neuropharmacology, 1985, Volume: 24, Issue:6 Topics: Animals; Blood Pressure; Desipramine; Dose-Response Relationship, Drug; Fenclonine; Fenfluramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Renin; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan	1985
Anorectic activities of serotonin uptake inhibitors: correlation with their potencies at inhibiting serotonin uptake in vivo and 3H-mazindol binding in vitro. Life sciences, 1988, Volume: 43, Issue:8 Topics: Animals; Appetite Depressants; Eating; Fluoxetine; Indoles; Male; Mazindol; Norepinephrine; Piperidines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists	1988
A role for serotonin in alpha-naphthylthiourea-induced pulmonary edema. Toxicology and applied pharmacology, 1984, Jun-30, Volume: 74, Issue:2 Topics: Animals; Blood Platelets; Clorgyline; Drug Interactions; Fluoxetine; Ketanserin; Lung; Male; Mice; Piperidines; Pulmonary Edema; Reserpine; Serotonin; Serotonin Antagonists; Thiourea; Thrombocytopenia	1984
Risperidone treatment for a Tourette's disorder patient with comorbid obsessive-compulsive disorder. The American journal of psychiatry, 1995, Volume: 152, Issue:7 Topics: Adult; Antipsychotic Agents; Comorbidity; Depressive Disorder; Drug Therapy, Combination; Fluoxetine; Humans; Isoxazoles; Male; Obsessive-Compulsive Disorder; Piperidines; Risperidone; Tourette Syndrome; Treatment Outcome	1995
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors. European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3 Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Fluvoxamine; Male; Mice; Paroxetine; Penbutolol; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sertraline; Synaptosomes	1994
Adverse interaction of cyproheptadine with serotonergic antidepressants. The Journal of clinical psychiatry, 1994, Volume: 55, Issue:7 Topics: Acute Disease; Cyproheptadine; Depressive Disorder; Drug Interactions; Female; Fluoxetine; Humans; Middle Aged; Monoamine Oxidase Inhibitors; Paranoid Disorders; Piperidines; Recurrence	1994
Monoamine systems in the discriminative effects of spiradoline, a kappa-opioid agonist. Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3 Topics: Analgesics; Animals; Avoidance Learning; Biogenic Monoamines; Discrimination, Psychological; Dopamine Antagonists; Fenfluramine; Fluoxetine; Generalization, Stimulus; Ketanserin; Male; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission	1994
Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties. European journal of pharmacology, 1993, Mar-02, Volume: 232, Issue:2-3 Topics: Animals; Antiemetics; Binding, Competitive; Cerebral Cortex; Cisplatin; Dose-Response Relationship, Drug; Ferrets; Fluoxetine; Granisetron; Indazoles; Male; Piperidines; Quipazine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Vomiting	1993
Behavioural effects of selective serotonin reuptake inhibitors following direct micro injection into the left red nucleus of the rat. Journal of psychopharmacology (Oxford, England), 1997, Volume: 11, Issue:1 Topics: 1-Naphthylamine; Animals; Behavior, Animal; Chlorpromazine; Citalopram; Fluoxetine; Fluvoxamine; Guanidines; Haloperidol; Male; Microinjections; Motor Activity; Paroxetine; Piperidines; Posture; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Selective Serotonin Reuptake Inhibitors; Sertraline	1997
Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats. European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy, Complex Partial; Fluoxetine; Hippocampus; Kindling, Neurologic; Male; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists	1998
Stress-induced release of anterior pituitary hormones: effect of H3 receptor-mediated inhibition of histaminergic activity or posterior hypothalamic lesion. Neuroendocrinology, 1999, Volume: 69, Issue:1 Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; beta-Endorphin; Fluoxetine; Histamine; Histamine Agonists; Histamine Antagonists; Hypothalamus, Posterior; Lipopolysaccharides; Male; Piperidines; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Receptors, Histamine H3; Restraint, Physical; Selective Serotonin Reuptake Inhibitors; Stress, Physiological	1999
Influence of fluoxetine and litoxetine on 5-HT4 receptor-mediated relaxation in the rat isolated oesophagus. Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:3 Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Esophagus; Fenclonine; Fluoxetine; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulfonamides	1999
Modulation by fluoxetine of striatal dopamine release following Delta9-tetrahydrocannabinol: a microdialysis study in conscious rats. British journal of pharmacology, 1999, Volume: 128, Issue:1 Topics: Animals; Consciousness; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Dronabinol; Fluoxetine; Male; Microdialysis; Perfusion; Piperidines; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors	1999
Effect of acute treatment with YM992 on extracellular serotonin levels in the rat frontal cortex. European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1 Topics: Analysis of Variance; Animals; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Dose-Response Relationship, Drug; Extracellular Space; Fluorobenzenes; Fluoxetine; Frontal Lobe; Male; Morpholines; p-Chloroamphetamine; Piperidines; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Serotonin Antagonists; Synaptosomes; Tritium; Venlafaxine Hydrochloride	2000
Effect of acute treatment with YM992 on extracellular norepinephrine levels in the rat frontal cortex. European journal of pharmacology, 2000, Apr-21, Volume: 395, Issue:1 Topics: Analysis of Variance; Animals; Antidepressive Agents; Citalopram; Cyclohexanols; Dose-Response Relationship, Drug; Extracellular Space; Fluorobenzenes; Fluoxetine; Frontal Lobe; Male; Morpholines; Norepinephrine; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Venlafaxine Hydrochloride	2000
Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice. Neuropharmacology, 2000, Jun-08, Volume: 39, Issue:8 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Buspirone; Diazepam; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Deletion; Guinea Pigs; Imipramine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Receptors, Neurokinin-1; Social Isolation; Stress, Psychological; Substance P; Tetrazoles; Vocalization, Animal	2000
The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Body Temperature; Columbidae; Corticosterone; Depression; Discrimination Learning; Drug Interactions; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lip; Male; Microdialysis; Neurons; Nicotine; Piperidines; Posture; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Smoking Cessation; Substance Withdrawal Syndrome; Sulfur Radioisotopes	2000
Inhibition of shock-induced foot tapping behaviour in the gerbil by a tachykinin NK1 receptor antagonist. European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Aprepitant; Conditioning, Operant; Diazepam; Female; Fluoxetine; Gerbillinae; Humans; Male; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1	2001
Antidepressant activity of memory-enhancing drugs in the reduction of submissive behavior model. European journal of pharmacology, 2002, Apr-05, Volume: 440, Issue:1 Topics: Animals; Antidepressive Agents; Competitive Behavior; Desipramine; Diazepam; Dioxoles; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intraperitoneal; Male; Maze Learning; Models, Animal; Nootropic Agents; Piperidines; Piracetam; Pyrrolidinones; Rats; Rats, Sprague-Dawley	2002
Evidence for serotonergic modulation of progesterone-induced hyperphagia, depression and algesia in female mice. Brain research, 2002, Jul-12, Volume: 943, Issue:2 Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Brain; Depression; Disease Models, Animal; Drug Interactions; Female; Fluoxetine; Hyperphagia; Menstrual Cycle; Mice; Mice, Inbred Strains; Motor Activity; Pain; Pain Measurement; Piperidines; Progesterone; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists	2002
Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice. Psychopharmacology, 2003, Volume: 166, Issue:3 Topics: Animals; Body Temperature; Cold Temperature; Crowding; Dose-Response Relationship, Drug; Fluorobenzenes; Fluoxetine; Hallucinogens; Ketanserin; Lethal Dose 50; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Platelet Aggregation Inhibitors; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Isolation; Stereoisomerism; Telemetry	2003
Effects of antidepressant drugs and GR 205171, an neurokinin-1 (NK1) receptor antagonist, on the response in the forced swim test and on monoamine extracellular levels in the frontal cortex of the mouse. Neuroscience letters, 2003, Jul-17, Volume: 345, Issue:2 Topics: Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Bupropion; Extracellular Space; Fluoxetine; Immobilization; Mice; Mice, Inbred Strains; Neurokinin-1 Receptor Antagonists; Piperidines; Prefrontal Cortex; Swimming; Tetrazoles; Time Factors	2003
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters. Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25 Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Reboxetine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters	2003
The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. European journal of pharmacology, 2004, Jun-16, Volume: 493, Issue:1-3 Topics: Animals; Autoreceptors; Cerebral Cortex; Chromatography, High Pressure Liquid; Citalopram; Fluoxetine; Guinea Pigs; Hypothalamus; Indoles; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Piperidines; Piperidones; Pyrimidines; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Presynaptic; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Spiro Compounds; Subcellular Fractions; Triazoles; Tritium; United Kingdom	2004
Hydroxyzine prevents isolation-induced vocalization in guinea pig pups: comparison with chlorpheniramine and immepip. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1 Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Chlorpheniramine; Dose-Response Relationship, Drug; Fluoxetine; Guinea Pigs; Histamine Agonists; Histamine H1 Antagonists; Hydroxyzine; Hypnotics and Sedatives; Imidazoles; Imipramine; Piperidines; Social Isolation; Vocalization, Animal	2004
Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents. Biological psychiatry, 2005, Feb-01, Volume: 57, Issue:3 Topics: Aggression; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Behavior, Animal; Depression; Diazepam; Dose-Response Relationship, Drug; Electroshock; Emotions; Fluoxetine; Gerbillinae; Immobility Response, Tonic; Male; Maze Learning; Mice; Models, Animal; Neuropsychological Tests; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant	2005
Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology. Biological psychiatry, 2005, May-15, Volume: 57, Issue:10 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Desipramine; Diazepam; Disease Models, Animal; Fluoxetine; Indoles; Male; Maze Learning; Obsessive-Compulsive Disorder; Piperazines; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptamines	2005
The selective 5-HT2A receptor antagonist M100907 enhances antidepressant-like behavioral effects of the SSRI fluoxetine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:12 Topics: Animals; Antidepressive Agents, Second-Generation; Brain Chemistry; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Fluorobenzenes; Fluoxetine; Male; Microdialysis; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists	2005
Preclinical pharmacology of F-98214-TA, a novel potent serotonin and norepinephrine uptake inhibitor with antidepressant and anxiolytic properties. Psychopharmacology, 2005, Volume: 182, Issue:3 Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Apomorphine; Dose-Response Relationship, Drug; Fluoxetine; Male; Mice; Motor Activity; Norepinephrine; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin	2005
Proteomic analysis of rat hippocampus and frontal cortex after chronic treatment with fluoxetine or putative novel antidepressants: CRF1 and NK1 receptor antagonists. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:7 Topics: Animals; Antidepressive Agents; Blotting, Western; Electrophoresis, Gel, Two-Dimensional; Fluoxetine; Frontal Lobe; Hippocampus; Male; Neurokinin-1 Receptor Antagonists; Peptide Mapping; Piperidines; Proteomics; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spectrum Analysis; Tetrazoles; Triazines	2006
Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine. British journal of pharmacology, 2006, Volume: 149, Issue:5 Topics: Adult; Antidepressive Agents, Second-Generation; Blotting, Western; Cell Line; Cell Membrane; Cisapride; Dose-Response Relationship, Drug; Drug Overdose; Ether-A-Go-Go Potassium Channels; Female; Fluoxetine; Humans; Long QT Syndrome; Membrane Potentials; Muscle Proteins; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Piperidines; Protein Transport; Pyridines; Sodium Channels; Time Factors; Transfection	2006
Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness. European journal of pharmacology, 2007, Jan-12, Volume: 554, Issue:2-3 Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Desipramine; Female; Fluoxetine; Maze Learning; Mice; Motor Activity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Swimming; Time Factors; Weight Gain	2007
The guinea pig forced swim test as a new behavioral despair model to characterize potential antidepressants. Psychopharmacology, 2007, Volume: 195, Issue:1 Topics: Amitriptyline; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Clozapine; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Investigational; Fluoxetine; Guinea Pigs; Injections, Intraperitoneal; Male; Methamphetamine; Monoamine Oxidase Inhibitors; Paroxetine; Piperidines; Selective Serotonin Reuptake Inhibitors; Swimming; Tranylcypromine	2007
3-[(Aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter. The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:10 Topics: Animals; Antidepressive Agents; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Ligands; Piperidines; Rabbits; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-2; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship	2007
Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation. Psychopharmacology, 2008, Volume: 201, Issue:3 Topics: Aminopyridines; Animals; Antidepressive Agents, Second-Generation; Astrocytes; Butadienes; Calcium; Cells, Cultured; Chelating Agents; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Fluoxetine; Gene Expression; Indoles; Maleimides; Mice; Nitriles; Phosphorylation; Piperidines; Protein Kinase C; Proto-Oncogene Proteins c-fos; Quinazolines; Receptor, Serotonin, 5-HT2B; RNA, Messenger; Signal Transduction; Substrate Specificity; Transcriptional Activation; Tyrphostins; Up-Regulation; Urea	2008
Neurokinin1 antagonists potentiate antidepressant properties of serotonin reuptake inhibitors, yet blunt their anxiogenic actions: a neurochemical, electrophysiological, and behavioral characterization. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:4 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Brain; Citalopram; Cricetinae; Dopamine; Drug Synergism; Fluoxetine; Gerbillinae; Isoindoles; Male; Mesocricetus; Mice; Neurokinin-1 Receptor Antagonists; Neurons; Norepinephrine; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Tetrazoles	2009
The MCH1 receptor antagonist SNAP 94847 induces sensitivity to dopamine D2/D3 receptor agonists in rats and mice. European journal of pharmacology, 2009, Jan-05, Volume: 602, Issue:1 Topics: Animals; Antidepressive Agents; Behavior, Animal; Fluoxetine; Locomotion; Mice; Mice, Inbred C57BL; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Somatostatin; Time Factors	2009
Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats. Addiction biology, 2009, Volume: 14, Issue:4 Topics: Adrenocorticotropic Hormone; Animals; Anti-Obesity Agents; Appetite Depressants; Cannabinoids; Conditioning, Operant; Corticosterone; Cues; Cyclobutanes; Environment; Feeding Behavior; Female; Fluoxetine; Fructose; Humans; Hypothalamo-Hypophyseal System; Motivation; Piperidines; Pituitary-Adrenal System; Pyrazoles; Rats; Reproducibility of Results; Rimonabant; Selective Serotonin Reuptake Inhibitors; Topiramate	2009
The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists. Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10 Topics: Acetylcholine; Administration, Oral; Amyloid beta-Protein Precursor; Animals; Antidepressive Agents; Biological Availability; Cerebral Cortex; CHO Cells; Cognition; Cricetinae; Cricetulus; Fluoxetine; Hippocampus; In Vitro Techniques; Maze Learning; Memory; Mice; Mice, Transgenic; Microsomes, Liver; Nootropic Agents; Penile Erection; Piperazines; Piperidines; Quinolines; Rats; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Structure-Activity Relationship	2010
Endothelin-1 and -3 modulate the neuronal norepinephrine transporter through multiple signalling pathways in the rat posterior hypothalamus. Neurochemistry international, 2010, Volume: 57, Issue:3 Topics: Adenylyl Cyclases; Animals; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Endothelin-3; Enzyme Activation; Fluoxetine; Hypothalamus, Posterior; Male; Neurons; Nitric Oxide; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oligopeptides; Piperidines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction	2010
NR2B subunit-specific NMDA antagonist Ro25-6981 inhibits the expression of conditioned fear: a comparison with the NMDA antagonist MK-801 and fluoxetine. Behavioural pharmacology, 2011, Volume: 22, Issue:2 Topics: Animals; Ataxia; Disease Models, Animal; Dizocilpine Maleate; Electroshock; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Fluoxetine; Freezing Reaction, Cataleptic; Locomotion; Male; Phenols; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors; Stereotypic Movement Disorder; Stress Disorders, Post-Traumatic	2011
hERG subunit composition determines differential drug sensitivity. British journal of pharmacology, 2011, Volume: 164, Issue:2b Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line, Transformed; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Fluoxetine; HEK293 Cells; Humans; Inhibitory Concentration 50; Long QT Syndrome; Piperidines; Protein Subunits; Pyridines; Sensitivity and Specificity; Torsades de Pointes	2011
Involvement of serotonergic system in the antidepressant-like effect of piperine. Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4 Topics: 5-Hydroxytryptophan; Alkaloids; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Brain Chemistry; Cerebral Cortex; Fenclonine; Fluoxetine; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming	2011
Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice. Behavioural brain research, 2011, Sep-30, Volume: 223, Issue:1 Topics: Animals; Antidepressive Agents; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Compulsive Behavior; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Endocannabinoids; Fluoxetine; Injections, Intraventricular; Male; Mice; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles	2011
Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT₄ receptor levels. The international journal of neuropsychopharmacology, 2012, Volume: 15, Issue:8 Topics: Analysis of Variance; Animals; Autoradiography; Brain; Dose-Response Relationship, Drug; Fluoxetine; Gene Expression Regulation; Genetic Variation; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Propane; Protein Binding; Radionuclide Imaging; Receptors, Serotonin, 5-HT4; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tritium	2012
Piperine protects epilepsy associated depression: a study on role of monoamines. European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:11 Topics: Alkaloids; Anhedonia; Animals; Anticonvulsants; Behavior, Animal; Benzodioxoles; Biogenic Monoamines; Brain Chemistry; Chromatography, Thin Layer; Convulsants; Depression; Epilepsy; Female; Fluoxetine; Male; Motor Activity; Pilocarpine; Piperidines; Polyunsaturated Alkamides; Postural Balance; Rats; Serotonin; Spectrophotometry, Infrared; Status Epilepticus; Swimming	2011
The neuropharmacology of prolactin secretion elicited by 3,4-methylenedioxymethamphetamine ("ecstasy"): a concurrent microdialysis and plasma analysis study. Hormones and behavior, 2012, Volume: 61, Issue:2 Topics: Animals; Female; Fluorobenzenes; Fluoxetine; Hallucinogens; Macaca mulatta; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Prolactin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Antagonists; Stereoisomerism; Time Factors	2012
Toxic interaction between fluoxetine and donepezil: a case of cholinergic toxidrome. The Journal of neuropsychiatry and clinical neurosciences, 2012,Spring, Volume: 24, Issue:2 Topics: Aged; Antidepressive Agents, Second-Generation; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Fluoxetine; Humans; Indans; Male; Piperidines	2012
Anxiety- rather than depression-like behavior is associated with adult neurogenesis in a female mouse model of higher trait anxiety- and comorbid depression-like behavior. Translational psychiatry, 2012, Oct-16, Volume: 2 Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Biomarkers; Dentate Gyrus; Depression; Disease Models, Animal; Female; Fluoxetine; Mice; Neurogenesis; Piperidines; Recurrence; Remission Induction; Thiazepines	2012
Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil. Journal of clinical anesthesia, 2013, Volume: 25, Issue:1 Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Fluoxetine; Humans; Intraoperative Complications; Male; Movement; Myoclonus; Piperidines; Propofol; Remifentanil; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Young Adult	2013
NK1 receptor antagonism lowers occupancy requirement for antidepressant-like effects of SSRIs in the gerbil forced swim test. Neuropharmacology, 2013, Volume: 73 Topics: Animals; Antidepressive Agents; Aprepitant; Citalopram; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Gerbillinae; HEK293 Cells; Humans; Immobility Response, Tonic; Male; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Prefrontal Cortex; Radioligand Assay; Receptors, Neurokinin-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins	2013
The antidepressant-like action of mGlu5 receptor antagonist, MTEP, in the tail suspension test in mice is serotonin dependent. Psychopharmacology, 2014, Volume: 231, Issue:1 Topics: Animals; Antidepressive Agents; Citalopram; Diet; Excitatory Amino Acid Antagonists; Fenclonine; Fluoxetine; Hindlimb Suspension; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Receptors, Kainic Acid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Thiazoles; Tryptophan	2014
Disruption of 5-HT2A receptor-PDZ protein interactions alleviates mechanical hypersensitivity in carrageenan-induced inflammation in rats. PloS one, 2013, Volume: 8, Issue:9 Topics: Animals; Bicuculline; Carrageenan; Disks Large Homolog 4 Protein; Fluorobenzenes; Fluoxetine; Hyperalgesia; Inflammation; Injections; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Pain; Peptides; Piperidines; Posterior Horn Cells; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists	2013
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:6 Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Comorbidity; Corticosterone; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Indoles; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Piperidines; Receptors, Serotonin, 5-HT4; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Sulfonamides; Time Factors	2014
Donepezil-induced hepatotoxicity in an elderly adult taking fluoxetine. Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:10 Topics: Aged; Alanine Transaminase; Alzheimer Disease; Antidepressive Agents, Second-Generation; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Donepezil; Fluoxetine; Humans; Indans; Male; Piperidines	2014
The effects of ifenprodil on the activity of antidepressant drugs in the forced swim test in mice. Pharmacological reports : PR, 2014, Volume: 66, Issue:6 Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Synergism; Fluoxetine; Imipramine; Mice; Morpholines; Piperidines; Reboxetine; Swimming; Thiazepines	2014
Effects of donepezil on hERG potassium channels. Brain research, 2015, Feb-09, Volume: 1597 Topics: Blotting, Western; Cell Membrane; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; HEK293 Cells; Humans; Indans; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Piperidines; Selective Serotonin Reuptake Inhibitors	2015
Chronic 5-HT4 receptor agonist treatment restores learning and memory deficits in a neuroendocrine mouse model of anxiety/depression. Neuroscience letters, 2016, Mar-11, Volume: 616 Topics: Aniline Compounds; Animals; Antidepressive Agents; Anxiety; Association Learning; Corticosterone; Depression; Fluoxetine; Learning; Male; Memory; Mice, Inbred C57BL; Piperidines; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT4 Receptor Agonists; Spatial Learning; Spatial Memory	2016
Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Metabolic brain disease, 2016, Volume: 31, Issue:4 Topics: Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Excitatory Amino Acid Antagonists; Fluoxetine; Imipramine; Mice; Motor Activity; Piperidines; Receptors, N-Methyl-D-Aspartate; Swimming; Treatment Outcome	2016
Nociceptin receptor antagonist SB 612111 decreases high fat diet binge eating. Behavioural brain research, 2016, 07-01, Volume: 307 Topics: Adaptation, Ocular; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Bulimia; Cycloheptanes; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Fluoxetine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Nociceptin Receptor; Piperidines; Receptors, Opioid; Sex Characteristics; Time Factors	2016
Antidepressant activity of nociceptin/orphanin FQ receptor antagonists in the mouse learned helplessness. Psychopharmacology, 2016, Volume: 233, Issue:13 Topics: Animals; Antidepressive Agents; Behavior, Animal; Cycloheptanes; Depressive Disorder; Disease Models, Animal; Fluoxetine; Helplessness, Learned; Male; Mice; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Nortriptyline; Opioid Peptides; Piperidines; Receptors, Opioid; Signal Transduction	2016
YL-0919, a dual 5-HT Acta pharmacologica Sinica, 2018, Volume: 39, Issue:1 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dendrites; Depression; Fluoxetine; Hippocampus; Male; Piperidines; Pyramidal Cells; Pyridones; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists	2018