fluoxetine has been researched along with phenytoin in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 16 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Bhat, MA; Ehtaishamul Haque, S; Khan, SA; Rana, A; Siddiqui, N | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Sen, S; Sinha, N | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Deng, XQ; Quan, ZS; Song, MX; Zheng, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jalil, P | 1 |
| Guidos, A; Joseph, AB; Leary, J; Wroblewski, BA | 1 |
| Campbell, M; Cueva, JE | 1 |
| Greenblatt, DJ; Shader, RI; von Moltke, LL | 1 |
| Darley, J | 1 |
| Coulter, DM; Pillans, P; Woods, DJ | 1 |
| Acharya, SB; Giriyappanavar, CR; Gurthu, S; Low, HC; Noor, AR; Quah, SH; Raju, SS | 1 |
| Preskorn, SH; Shad, MU | 1 |
| Birnbaum, AK; Nelson, MH; Remmel, RP | 1 |
| Belmaker, RH; Bersudsky, Y; Nemets, B | 1 |
| Harasztosi, C; Kecskeméti, V; Nánási, PP; Pál, B; Riba, P; Rusznák, Z; Szûcs, G; Wagner, R | 1 |
| Belmaker, RH; Nemets, B; Shapira, B; Trachtenberg, A | 1 |
| Borowicz, KK; Czuczwar, SJ; Furmanek-Karwowska, K; Luszczki, JJ; Sawicka, K | 1 |
| Brown, HS; Chadwick, A; Houston, JB | 1 |
| Lance, S; Ternouth, I | 1 |
| Basavaraju, R; Mangalore, S; Mehta, UM; Narasimha, VL | 1 |
2 review(s) available for fluoxetine and phenytoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
2 trial(s) available for fluoxetine and phenytoin
| Article | Year |
|---|---|
Controlled double-blind trial of phenytoin vs. fluoxetine in major depressive disorder.
Topics: Adult; Age of Onset; Anticonvulsants; Depressive Disorder, Major; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Psychiatric Status Rating Scales; Recurrence; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2005 |
Phenytoin as an augmentation for SSRI failures: a small controlled study.
Topics: Adult; Aged; Anticonvulsants; Depressive Disorder, Major; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Fluoxetine; Fluvoxamine; Humans; Male; Middle Aged; Paroxetine; Personality Inventory; Phenytoin; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2006 |
32 other study(ies) available for fluoxetine and phenytoin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
N-{[(6-substituted-1,3-benzothiazole-2-yl)amino]carbonothioyl}-2/4-substituted benzamides: synthesis and pharmacological evaluation.
Topics: Animals; Anticonvulsants; Benzamides; Benzothiazoles; Central Nervous System Depressants; Chemical and Drug Induced Liver Injury; Liver Function Tests; Male; Mice; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Sulfides | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Design, synthesis and evaluation of the antidepressant and anticonvulsant activities of triazole-containing quinolinones.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Exploratory Behavior; Male; Mice; Mice, Inbred Strains; Molecular Structure; Quinolones; Rotarod Performance Test; Seizures; Swimming; Triazoles | 2014 |
Toxic reaction following the combined administration of fluoxetine and phenytoin: two case reports.
Topics: Aged; Aged, 80 and over; Depressive Disorder; Drug Therapy, Combination; Epilepsy; Female; Fluoxetine; Humans; Middle Aged; Nervous System Diseases; Neurologic Examination; Phenytoin | 1992 |
Control of depression with fluoxetine and antiseizure medication in a brain-injured patient.
Topics: Adult; Brain Injuries; Depressive Disorder; Drug Therapy, Combination; Fluoxetine; Humans; Male; Phenytoin; Seizures | 1992 |
Fluoxetine inhibition of phenytoin metabolism.
Topics: Brain; Dose-Response Relationship, Drug; Fluoxetine; Humans; Liver; Metabolic Clearance Rate; Phenytoin | 1994 |
Interaction between phenytoin and fluoxetine.
Topics: Adult; Depressive Disorder; Dose-Response Relationship, Drug; Epilepsy; Fluoxetine; Humans; Male; Phenytoin | 1994 |
Interaction of phenytoin and fluoxetine.
Topics: Contraindications; Drug Interactions; Female; Fluoxetine; Humans; Middle Aged; Phenytoin; Seizures | 1994 |
Effect of fluoxetine on maximal electroshock seizures in mice: acute vs chronic administration.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Fluoxetine; Male; Mice; Mice, Inbred ICR; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors | 1999 |
Drug-drug interaction in reverse: possible loss of phenytoin efficacy as a result of fluoxetine discontinuation.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy, Tonic-Clonic; Fluoxetine; Humans; Male; Phenytoin; Selective Serotonin Reuptake Inhibitors; Substance Withdrawal Syndrome | 1999 |
Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors.
Topics: Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Child, Preschool; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluoxetine; Humans; Hydroxylation; Male; Microsomes, Liver; Middle Aged; Paroxetine; Phenytoin; Selective Serotonin Reuptake Inhibitors; Sertraline; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2001 |
Drug interactions with selective serotonin reuptake inhibitors, especially with other psychotropics.
Topics: Anticoagulants; Anticonvulsants; Antidepressive Agents, Second-Generation; Carbamazepine; Contraindications; Drug Interactions; Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Phenytoin; Selective Serotonin Reuptake Inhibitors | 2001 |
Norfluoxetine and fluoxetine have similar anticonvulsant and Ca2+ channel blocking potencies.
Topics: Animals; Anticonvulsants; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Clonazepam; Cochlear Nucleus; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Fluoxetine; Male; Membrane Potentials; Mice; Neurons, Afferent; Patch-Clamp Techniques; Phenytoin; Selective Serotonin Reuptake Inhibitors | 2005 |
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Drug Synergism; Electroshock; Fluoxetine; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2007 |
Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.
Topics: Animals; Catalysis; Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Fluconazole; Fluoxetine; Fluvoxamine; Hepatocytes; Ketoconazole; Kinetics; Male; Miconazole; Microsomes, Liver; Midazolam; Phenytoin; Quinine; Rats; Rats, Sprague-Dawley; Tolbutamide | 2007 |
Fluoxetine-induced phenytoin toxicity: a clinical reminder about the perils of polypharmacy.
Topics: Antidepressive Agents, Second-Generation; Drug Interactions; Epilepsy; Female; Fluoxetine; Humans; Middle Aged; Phenytoin; Polypharmacy | 2015 |
Precuneus and psychiatric manifestations: Novel neurobiological formulations through lesion based connectivity mapping of psychopathology.
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brain Mapping; Brain Neoplasms; Depressive Disorder, Major; Diagnosis, Differential; Electroconvulsive Therapy; Female; Fluoxetine; Granuloma; Humans; Magnetic Resonance Imaging; Middle Aged; Parietal Lobe; Phenytoin; Quetiapine Fumarate; Schizophrenia, Paranoid; Seizures | 2019 |