fluoxetine and perphenazine

fluoxetine has been researched along with perphenazine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's7 (33.33)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ang, KK; Arkin, MR; Chen, S; Doyle, PS; Engel, JC; McKerrow, JH1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Glickman, L; Lampke, R; Viswanathan, R1
Rothschild, AJ1
Bessette, MP; Carter-Campbell, JT; Rothschild, AJ; Samson, JA1
Benjamin, S; Connor, DF; Ozbayrak, KR1
De Meester, I; Desnyder, R; Maes, M; Meltzer, HY; Ranjan, R; Scharpe, S1
Diaz, A; Fouilloux, C; Ortiz, S1
Duval, SE; Rothschild, AJ1
Ahmadi, A; Khazaie, H; Moradi, M; Tahmasian, M1
D'Ambrosio, JC; Raguveer, V; Varshney, A1

Reviews

1 review(s) available for fluoxetine and perphenazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for fluoxetine and perphenazine

ArticleYear
Efficacy of the combination of fluoxetine and perphenazine in the treatment of psychotic depression.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:9

    Topics: Adult; Amoxapine; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Fluoxetine; Humans; Male; Middle Aged; Perphenazine; Psychiatric Status Rating Scales

1993
Open trial study of a combined antidepressant (amitryptiline, perphenazine, diazepam) versus fluoxetine or imipramine in ambulatory depressed patients.
    Proceedings of the Western Pharmacology Society, 2002, Volume: 45

    Topics: Adolescent; Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Depressive Disorder; Diazepam; Drug Combinations; Female; Fluoxetine; Humans; Imipramine; Male; Middle Aged; Perphenazine; Prospective Studies; Psychiatric Status Rating Scales

2002
How long should patients with psychotic depression stay on the antipsychotic medication?
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:4

    Topics: Acute Disease; Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Clinical Protocols; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Middle Aged; Perphenazine; Prospective Studies; Psychiatric Status Rating Scales; Secondary Prevention; Time Factors

2003

Other Studies

17 other study(ies) available for fluoxetine and perphenazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:8

    Topics: Animals; Cattle; Cell Line; Cell Line, Tumor; Chagas Disease; Drug Evaluation, Preclinical; Hepatocytes; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted; Muscle, Skeletal; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma cruzi

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Cessation of menses due to perphenazine rather than fluoxetine?
    The American journal of psychiatry, 1990, Volume: 147, Issue:12

    Topics: Amenorrhea; Female; Fluoxetine; Humans; Menstruation; Perphenazine

1990
Delirium: an SSRI-benztropine adverse effect?
    The Journal of clinical psychiatry, 1995, Volume: 56, Issue:11

    Topics: Adult; Age Factors; Aged; Benztropine; Delirium; Drug Interactions; Fluoxetine; Humans; Middle Aged; Perphenazine; Schizophrenia; Selective Serotonin Reuptake Inhibitors

1995
Case study: neuroleptic withdrawal dyskinesia exacerbated by ongoing stimulant treatment.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:11

    Topics: Antipsychotic Agents; Dextroamphetamine; Diphenhydramine; Fluoxetine; Humans; Male; Mental Disorders; Movement Disorders; Perphenazine; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome; Videotape Recording

1995
Alterations in plasma dipeptidyl peptidase IV enzyme activity in depression and schizophrenia: effects of antidepressants and antipsychotic drugs.
    Acta psychiatrica Scandinavica, 1996, Volume: 93, Issue:1

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Female; Fluoxetine; Haloperidol; Humans; Hydrocortisone; Imipramine; Male; Middle Aged; Nortriptyline; Perphenazine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1996
Treatment of idiopathic recurrent priapism with fluoxetine and low dose Perphenazine.
    JPMA. The Journal of the Pakistan Medical Association, 2008, Volume: 58, Issue:3

    Topics: Adult; Antipsychotic Agents; Anxiety; Depression; Fluoxetine; Humans; Male; Perphenazine; Priapism; Secondary Prevention; Selective Serotonin Reuptake Inhibitors

2008
Serotonin Syndrome: Difficult to Diagnose but Critical to Treat.
    Delaware medical journal, 2015, Volume: 87, Issue:11

    Topics: Adult; Antipsychotic Agents; Cyproheptadine; Diagnosis, Differential; Female; Fluoxetine; Humans; Perphenazine; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Syndrome

2015