fluoxetine and ondansetron

fluoxetine has been researched along with ondansetron in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (23.53)18.2507
2000's11 (32.35)29.6817
2010's14 (41.18)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Jia, L; Sun, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jørgensen, H; Knigge, U; Warberg, J1
Ikeda, T; Matsumoto, M; Saito, H; Tochihara, M; Togashi, H; Yoshioka, M1
Meert, TF1
Koriech, OM1
Bourin, M; Redrobe, JP1
Bagdy, E; Harsing, LG; Solyom, S1
Fundaró, A1
Costall, B; Neill, JC; Wilson, AW1
Herges, S; Taylor, DA1
Anjaneyulu, M; Chopra, K1
Freeman, SL; Glatzle, J; Raybould, HE; Robin, CS; Sharp, JW; Sternini, C; Valdellon, M1
Borah, M; Radhakrishnan, M; Ramamoorthy, R1
Limebeer, CL; Litt, DE; Parker, LA1
Adrien, J; Escourrou, P; Real, C; Seif, I1
Carley, DW; Herdegen, JJ; Logan, T; Olopade, C; Prasad, B; Radulovacki, M1
Feizy, F; Malayeri, A; Motlagh, I; Sayyah, M; Siahpoosh, A; Soltani, F1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR1
Gupta, D; Kurhe, Y; Radhakrishnan, M1
Bailey, D; Catlett, SL; Sumaya, IC1
Khin, PP; Sohn, UD; Zaw, TS1
Guo, D; Guo, J; Huang, S; Li, Q; Polli, JE; Shu, Y; Xiong, Z; Ye, Z; Zhang, W; Zhou, H; Zhu, P1
Blasco-Ibañez, JM; Crespo, C; Nácher, J; Olivas-Cano, I; Rodriguez-Andreu, JM; Varea, E1

Reviews

1 review(s) available for fluoxetine and ondansetron

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for fluoxetine and ondansetron

ArticleYear
Prospective trial of efficacy and safety of ondansetron and fluoxetine in patients with obstructive sleep apnea syndrome.
    Sleep, 2010, Volume: 33, Issue:7

    Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Middle Aged; Ondansetron; Polysomnography; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Severity of Illness Index; Sleep Apnea, Obstructive; Treatment Outcome

2010
A double-blind, placebo-controlled pilot study of ondansetron for patients with obsessive-compulsive disorder.
    Human psychopharmacology, 2010, Volume: 25, Issue:6

    Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Humans; Interview, Psychological; Male; Middle Aged; Obsessive-Compulsive Disorder; Ondansetron; Outpatients; Pilot Projects; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Treatment Outcome

2010

Other Studies

31 other study(ies) available for fluoxetine and ondansetron

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Involvement of 5-HT1, 5-HT2, and 5-HT3 receptors in the mediation of the prolactin response to serotonin and 5-hydroxytryptophan.
    Neuroendocrinology, 1992, Volume: 55, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Ergolines; Fluoxetine; Imidazoles; Indoles; Ketanserin; Male; Methysergide; Ondansetron; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron

1992
Modulation of norepinephrine release by serotonergic receptors in the rat hippocampus as measured by in vivo microdialysis.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Animals; Calcium; Fluoxetine; Hippocampus; Male; Microdialysis; Nerve Endings; Norepinephrine; Ondansetron; Potassium; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1995
Effects of various serotonergic agents on alcohol intake and alcohol preference in Wistar rats selected at two different levels of alcohol preference.
    Alcohol and alcoholism (Oxford, Oxfordshire), 1993, Volume: 28, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Animals; Buspirone; Chlordiazepoxide; Citalopram; Dose-Response Relationship, Drug; Drinking; Fluoxetine; Male; Ondansetron; Rats; Receptors, Serotonin; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Fluoxetine treatment comprises the antiemetic efficacy of ondansetron in cancer patients.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1995, Volume: 7, Issue:6

    Topics: Adult; Antiemetics; Binding, Competitive; Female; Fluoxetine; Humans; Male; Middle Aged; Neoplasms; Ondansetron

1995
Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Citalopram; Desipramine; Drug Interactions; Fluoxetine; Fluvoxamine; Imipramine; Ketanserin; Male; Maprotiline; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

1997
Feedback stimulation of somatodendritic serotonin release: a 5-HT3 receptor-mediated effect in the raphe nuclei of the rat.
    Brain research bulletin, 1998, Volume: 45, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dendrites; Electric Stimulation; Feedback; Fluoxetine; In Vitro Techniques; Male; Neural Pathways; Ondansetron; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

1998
Pinch-induced catalepsy in mice: a useful model to investigate antidepressant or anxiolytic drugs.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Antidepressive Agents; Catalepsy; Female; Fluoxetine; Fluvoxamine; Imipramine; Learning; Male; Mice; Models, Psychological; Motor Activity; Ondansetron; Physical Stimulation; Reaction Time; Serotonin Antagonists; Sex Characteristics; Stereotyped Behavior

1998
An investigation into the effects of 5-HT agonists and receptor antagonists on ethanol self-administration in the rat.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:3

    Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Ethanol; Female; Fenfluramine; Fluoxetine; Metergoline; Ondansetron; Piperazines; Rats; Rats, Sprague-Dawley; Ritanserin; Selective Serotonin Reuptake Inhibitors; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

1998
Involvement of 5-HT(3) receptors in the nucleus accumbens in the potentiation of cocaine-induced behaviours in the rat.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Animals; Behavior, Animal; Cocaine; Drug Synergism; Fluoxetine; Motor Activity; Nucleus Accumbens; Ondansetron; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Time Factors

2000
Fluoxetine attenuates thermal hyperalgesia through 5-HT1/2 receptors in streptozotocin-induced diabetic mice.
    European journal of pharmacology, 2004, Aug-30, Volume: 497, Issue:3

    Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fluoxetine; Hot Temperature; Hyperalgesia; Male; Mice; Ondansetron; Pindolol; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT2; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Streptozocin; Time Factors; Touch

2004
Ligand-induced 5-HT3 receptor internalization in enteric neurons in rat ileum.
    Gastroenterology, 2006, Volume: 131, Issue:1

    Topics: Animals; Blotting, Western; Fluoxetine; Ileum; Immunohistochemistry; Intestinal Absorption; Intestinal Mucosa; Male; Myenteric Plexus; Neurons; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2006
Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models.
    Behavioural pharmacology, 2008, Volume: 19, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Fluoxetine; Hindlimb Suspension; Male; Maze Learning; Mice; Motor Activity; Olfactory Bulb; Ondansetron; Paroxetine; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Stress, Psychological; Venlafaxine Hydrochloride

2008
Effect of 5-HT3 antagonists and a 5-HT(1A) agonist on fluoxetine-induced conditioned gaping reactions in rats.
    Psychopharmacology, 2009, Volume: 203, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Autoreceptors; Conditioning, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Isoquinolines; Lithium Chloride; Male; Nausea; Ondansetron; Palonosetron; Quinuclidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists

2009
Ondansetron and fluoxetine reduce sleep apnea in mice lacking monoamine oxidase A.
    Respiratory physiology & neurobiology, 2009, Sep-30, Volume: 168, Issue:3

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Mice; Mice, Inbred C3H; Mice, Knockout; Monoamine Oxidase; Ondansetron; Plethysmography, Whole Body; Respiratory Mechanics; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sleep Apnea Syndromes; Wakefulness

2009
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes

2013
Ondansetron, a 5HT3 receptor antagonist reverses depression and anxiety-like behavior in streptozotocin-induced diabetic mice: possible implication of serotonergic system.
    European journal of pharmacology, 2014, Dec-05, Volume: 744

    Topics: Animals; Antidepressive Agents; Antiemetics; Anxiety; Behavior, Animal; Brain; Depression; Depressive Disorder; Diabetes Mellitus, Experimental; Exploratory Behavior; Fluoxetine; Male; Mice; Motor Activity; Ondansetron; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Streptozocin; Swimming

2014
Differential effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methyl-5-HT, and the SSRI, fluoxetine.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 144

    Topics: Animals; Depression; Diet, High-Fat; Disease Models, Animal; Fluoxetine; Male; Ondansetron; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists

2016
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
    Pharmacology, 2017, Volume: 99, Issue:5-6

    Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; Drug Interactions; Electric Stimulation; Estrenes; Fluoxetine; Glyburide; Ileum; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Ondansetron; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Sulfonamides; Tetraethylammonium

2017
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Pharmaceutical research, 2018, Oct-25, Volume: 35, Issue:12

    Topics: Amitriptyline; Animals; Drug Interactions; Fluoxetine; HEK293 Cells; Humans; Imipramine; Irinotecan; Mice, Inbred C57BL; Morphine; Narcotics; Ondansetron; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tissue Distribution; Verapamil

2018
Fluoxetine increased adult neurogenesis is mediated by 5-HT3 receptor.
    Neuroscience letters, 2023, 01-31, Volume: 795

    Topics: Animals; Cell Proliferation; Dentate Gyrus; Fluoxetine; Hippocampus; Neural Stem Cells; Neurogenesis; Ondansetron; Rats; Receptors, Serotonin, 5-HT3

2023