fluoxetine has been researched along with nisoxetine in 286 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (15.38) | 18.7374 |
| 1990's | 81 (28.32) | 18.2507 |
| 2000's | 114 (39.86) | 29.6817 |
| 2010's | 42 (14.69) | 24.3611 |
| 2020's | 5 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, ND; Robertson, DW; Swartzendruber, JK; Wong, DT; Yang, KS | 1 |
| Cortizo, L; García, N; Innerárity, A; Labeaga, L; Mosquera, R; Orjales, A; Pumar, MC; Toledo, A | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Andersen, J; Bang-Andersen, B; Eildal, JN; Jørgensen, AM; Jørgensen, M; Kristensen, AS; Strømgaard, K | 1 |
| Ching, B; Fleck, BA; Gao, Y; Gogas, K; Hudson, S; Pontillo, J; Wade, WS; Wu, D | 1 |
| Dwight, W; Eccles, W; Fleck, BA; Genicot, MJ; Gogas, K; Hudson, S; Kiankarimi, M; Mostofi, YS; Wade, WS | 1 |
| Alfinito, P; Bray, J; Cohn, ST; Deecher, DC; Fensome, A; Johnston, G; Koury, E; Mahaney, PE; Marella, MA; McComas, CC; Nogle, L; Trybulski, EJ; Vu, AT; Ye, F; Zhang, P | 1 |
| Childers, SR; Davies, HM; Manning, JR; Sexton, T | 1 |
| Bush, LR; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Koch, P; Ma, J; Malcolm, SC; Saraswat, LD; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F | 1 |
| Campbell, JE; Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Ma, J; Malcolm, SC; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F | 1 |
| Campbell, UC; Engel, SR; Hardy, LW; Hewitt, MC; Jiang, ZD; Ma, J; Malcolm, SC; Schreiber, R; Shao, L; Spear, KL; Spicer, NA; Varney, MA; Wang, F | 1 |
| Choi, K; Moon, B; Park, JE; Roh, EJ; Sim, T; Song, C | 1 |
| Cheon, SH; Choi, K; Hahn, HG; Han, M; Song, C; Yun, J | 1 |
| Hahn, HG; Han, M; Jeong, N; Song, C | 1 |
| Tessel, RE; Tyler, TD | 1 |
| Bond, A; Neal, H | 1 |
| Jones, GT; Moore, RA; Slater, IH | 1 |
| Schmidt, MJ; Thornberry, JF | 1 |
| Janowsky, A; Mishra, R; Sulser, F | 1 |
| Fuller, RW; Perry, KW; Snoddy, HD | 1 |
| Billings, R; Lemberger, L; Rowe, H; Terman, S | 1 |
| Bymaster, FB; Fuller, RW; Perry, KW; Wong, DT | 1 |
| Cohen, ML; Wiley, KS | 1 |
| Bymaster, FP; Wong, DT | 2 |
| Bymaster, FP; Horng, JS; Wong, DT | 1 |
| Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| Bauer, ME; Tejani-Butt, SM | 1 |
| Blum, B; Bönisch, H; Michael-Hepp, J | 1 |
| Byrd, LD; Howell, LL | 1 |
| Ordway, GA; Tejani-Butt, SM | 1 |
| Tejani-Butt, SM | 1 |
| Cox, BM; Izenwasser, S; Jacocks, HM; Werling, LL | 1 |
| Bäckström, IT; Marcusson, JO | 1 |
| Boura, AL; Jansakul, C; King, RG | 1 |
| Brunswick, DJ; Frazer, A; Tejani-Butt, SM | 1 |
| Cox, BM; Izenwasser, S; Werling, LL | 1 |
| Breese, GR; Duncan, GE; Hong, JS; Kuhn, C; Mueller, RA; Paul, IA | 1 |
| Haka, MS; Kilbourn, MR | 1 |
| Gonzales, RA; Moerschbaecher, JM; Mosaddeghi, M | 1 |
| Bäckström, IT; Marcusson, JO; Ross, SB | 1 |
| Izenwasser, S; Kornetsky, C | 2 |
| Goldstein, FJ; Kellstein, DE; Malseed, RT; Ossipov, MH | 1 |
| Lemberger, L | 1 |
| Creese, MW; Grunewald, GL | 1 |
| Haynes, J; Pennefather, JN | 1 |
| Foley, AJ; Leedham, JA; Pennefather, JN | 1 |
| Abrahamsson, T; Carlsson, L | 1 |
| Boja, JW; Schechter, MD | 1 |
| Ieni, JR; Meyerson, LR; Wennogle, LP | 1 |
| Woolverton, WL | 1 |
| Goldberg, LI; Kamien, JB; Woolverton, WL | 1 |
| Holman, RB; Snape, BM | 1 |
| Snoddy, AM; Tessel, RE | 2 |
| Fingerman, M; Hanumante, MM | 1 |
| Best, KL; Bymaster, FP; Threlkeld, PG; Wong, DT | 1 |
| Henderson, JK; Hynes, MD | 1 |
| Gershon, S; Kelwala, S; Stanley, M | 1 |
| Brooks, JC; Burke, DH; Treml, SB | 1 |
| Fuller, RW; Hemrick-Luecke, SK | 1 |
| Carter, RB; Leander, JD | 1 |
| Maj, J; Rogóz, Z; Skuza, G; Sowińska, H | 1 |
| Jobe, PC; Ray, TB | 1 |
| Leander, JD; McCleary, PE | 1 |
| Sugrue, MF | 1 |
| Delashaw, JB; Dement, WC; Foutz, AS; Guilleminault, C | 1 |
| Tella, SR | 1 |
| Fuller, RW; Gehlert, DR; Hemrick-Luecke, SK; Howbert, JJ; Krushinski, J; Robertson, DW; Schober, DA; Wong, DT | 1 |
| Gackenheimer, SL; Gehlert, DR; Schober, DA | 1 |
| Alexoff, DA; Chen, R; Dewey, SL; Ding, YS; Fowler, JS; Gatley, SJ; Pan, D | 1 |
| Goldberg, SR; Tella, SR | 1 |
| Chen, NH; Reith, ME | 1 |
| Paré, WP; Tejani-Butt, SM; Yang, J | 1 |
| Kropp, BP; Springer, JP; Thor, KB | 1 |
| Hennies, HH; Reimann, W | 1 |
| Bayer, BM; Berkeley, MB; Daussin, S; Hernandez, MC | 1 |
| Tejani-Butt, SM; Yang, J | 1 |
| Ganapathy, V; Jayanthi, LD; Leibach, FH; Mahesh, VB; Prasad, PD; Ramamoorthy, S | 1 |
| Goldberg, SR; Schindler, CW; Tella, SR | 1 |
| Gackenheimer, SL; Gehlert, DR; Robertson, DW | 1 |
| Tejani-Butt, SM; Yang, J; Zaffar, H | 1 |
| Bouras, C; Charnay, Y; Hof, PR; Jouvet, M; Leger, L; Vallet, PG | 1 |
| Butler, SA; Cheetham, SC; Heal, DJ; Prow, MR; Viggers, JA | 1 |
| Childers, SR; Davies, HM; Kuhn, LA; Matasi, JJ; Sexton, T; Thornley, C | 1 |
| Kurz, T; Offner, B; Richardt, G; Schömig, A; Schreieck, J; Tölg, R | 1 |
| Abraham, P; Blough, BE; Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH | 1 |
| Darmani, NA | 2 |
| Abraham, P; Boja, JW; Carroll, FI; Holmquist, CR; Keverline-Frantz, KI; Kuhar, MJ | 1 |
| Cochran, PK; Evans, VR; Hitchcock, JM; Nyquist-Battie, C; Unal, C | 1 |
| Barros, HM; Belej, T; Manji, D; Nobrega, JN; Sioutis, S | 1 |
| Darmani, NA; Reeves, SL | 1 |
| Ordway, GA; Zhu, MY | 1 |
| Etgen, AM; Sokol, J; Vathy, I | 1 |
| Choi, S; Kellogg, CK; Weisberg, SN | 1 |
| Cason, GW; Klimek, V; Ordway, GA; Stockmeier, CA | 1 |
| Blount, I; Bzoskie, I; Humme, J; Kashiwai, K; Padbury, JF | 1 |
| Besnard, JC; Boazi, M; Bricard, J; Caillet, M; Chalon, S; Emond, P; Frangin, Y; Garreau, L; Guilloteau, D; Mauclaire, L | 1 |
| Mellerup, ET; Plenge, P | 1 |
| Heal, DJ; Hutchins, LJ; Jackson, HC; Mazurkiewicz, SE; Needham, AM | 1 |
| Charnay, Y; De Saint Hilaire, Z; Merica, H; Mikolajewski, R; Python, A | 1 |
| Paré, WP; Tejani-Butt, SM; Zafar, HM | 1 |
| Dilley, G; Kalka, S; Klimek, V; Meltzer, HY; Ordway, GA; Overholser, J; Stockmeier, C | 1 |
| Avor, K; Basmadjian, GP; Chan, HM; Hall, N; Seale, TW; Singh, S | 1 |
| Meyer, JS; Shearman, LP | 2 |
| Camarasa, J; Camins, A; Escubedo, E; Gasulla, D; Pallàs, M; Pubill, D; Sureda, FX | 1 |
| Kleven, MS; Koek, W | 1 |
| Dailey, JW; Jobe, PC; Steenbergen, JL; Yan, QS | 1 |
| D'Alonzo, AJ; Darbenzio, RB; Dorso, CR; Grover, GJ; Zhu, JL | 1 |
| Apparsundaram, S; Blakely, RD; Ordway, GA; Zhu, MY | 1 |
| McReynolds, AM; Meyer, JS | 1 |
| Béïque, JC; de Montigny, C; Debonnel, G; Lavoie, N | 1 |
| Chen, N; Justice, JB; Trowbridge, CG | 1 |
| Heal, DJ; Kilpatrick, IC; Needham, PL; Rowley, HL | 2 |
| Apparsundaram, S; Blakely, RD; Giovanetti, E; Schroeter, S | 1 |
| Holtzman, SG; Waddell, AB | 1 |
| Barrier, L; Chalon, S; Huguet, F; Page, G; Piriou, A | 1 |
| Cassis, LA; Dwoskin, LP; King, VL | 1 |
| Boja, JW; Dluzen, DE; Shang, Y | 1 |
| Blakely, RD; Jansen, K; Richelson, E; Tatsumi, M | 1 |
| Chariot, J; Nagain-Domaine, C; Presset, O; Rozé, C | 2 |
| Carmolli, M; Cumbay, M; Eshleman, AJ; Janowsky, A; Martens, CR; Neve, KA | 1 |
| Connoley, IP; Frost, I; Heal, DJ; Liu, YL; Reckless, IP; Stock, MJ | 1 |
| Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Pallàs, M; Pubill, D; Sureda, FX | 1 |
| Bagli, M; Huether, G; Moll, GH; Rothenberger, A; Rüther, E; Wegerer, V | 1 |
| Inazu, M; Kiuchi, Y; Kubota, N; Matsumiya, T; Oguchi, K; Takeda, H; Zhang, J | 1 |
| Ferrel, A; Figlewicz, DP; Schaefer, J; Zavosh, A | 1 |
| Danek Burgess, KS; Justice, JB | 1 |
| Berthold, F; Bönisch, H; Hadrich, D; Steckhan, E | 1 |
| De Oliveira, K; Hennings, EC; Kiss, JP; Toth, PT; Vizi, ES | 1 |
| Esteban, S; García-Sevilla, JA; Lladó, J; Sastre-Coll, A | 1 |
| Carroll, FI; French, D; Izenwasser, S; Kunko, PM | 1 |
| Hébert, C; Lalonde, R; Reader, TA; Strazielle, C | 1 |
| Blundell, P; Gonzalez, MD; Liang, AY; Madras, BK; Meltzer, PC; Niznik, HB; Pristupa, ZB | 1 |
| Izenwasser, S; Katz, JL; Terry, P | 1 |
| Bock, N; Huether, G; Mehnert, C; Moll, GH; Rothenberger, A; Rüther, E; Wicker, M | 1 |
| Harkin, A; Nowak, G; Paul, IA | 1 |
| Carroll, FI; Kimmel, HL; Kuhar, MJ | 1 |
| Knight, DL; Nemeroff, CB; Owens, MJ | 1 |
| Butterworth, RF; Michalak, A; Rose, C | 1 |
| Elie, R; Habimana, A; Hébert, C; Reader, TA | 1 |
| Li, J; Ordway, GA; Shamburger, S; Zhu, MY | 1 |
| Brodde, OE; Leineweber, K; Seyfarth, T | 1 |
| Hause, S; Huether, G; Moll, GH; Rothenberger, A; Rüther, E | 1 |
| Atcheson, R; Heffernan, AM; Joyce, PI; Lambert, DG; Marcus, RJ; Rowbotham, DJ | 1 |
| Dluzen, DE; Shang, Y | 2 |
| Jung, JS; Kim, HD; Kim, HS; Kim, KW; Kim, YH; Song, DK; Suh, HW; Woo, RS | 1 |
| Dohi, T; Kitayama, S; Morita, K | 1 |
| Abdali, SA; Kalsner, S | 1 |
| Apparsundaram, S; Blakely, RD; Price, RD; Sung, U | 1 |
| Bryan-Lluka, LJ; Paczkowski, FA | 2 |
| Hodgson, WC; Ramasamy, S; Ventura, S | 1 |
| Brockington, A; Hope, BT; Morón, JA; Rocha, BA; Wise, RA | 1 |
| Ase, AR; Lalonde, R; Reader, TA; Strazielle, C | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA | 1 |
| Dohi, T; Kitayama, S; Kumagai, K; Morita, K | 1 |
| DeFelice, LJ; Jayanthi, LD; Vargas, G | 1 |
| Rehavi, M; Roz, N; Weizman, A | 1 |
| Bönisch, H; Bryan-Lluka, LJ; Paczkowski, FA; Runkel, F; Sucic, S | 1 |
| Hirshfeld, A; Mazur, Y; Rehavi, M; Roz, N | 1 |
| Gnegy, M; Kantor, L; Park, YH; Wang, KK | 1 |
| Caron, M; Hall, FS; Lesch, KP; Li, XF; Murphy, DL; Sora, I; Uhl, GR; Xu, F | 1 |
| Bergman, J; Brust, P; Eskola, O; Forsback, S; Grönroos, T; Haaparanta, M; Lehikoinen, P; Marjamäki, P; Solin, O; Steinbach, J; Zessin, J | 1 |
| Jeong, MS; Kim, CJ; Kim, KW; Park, EY; Park, JW; Shin, BS; Shin, MS; Woo, RS; Zhao, RJ | 1 |
| Beilfuss, A; Brandt, K; Brodde, OE; Heinroth-Hoffmann, I; Leineweber, K; Pönicke, K; Wludyka, B | 1 |
| Bryan-Lluka, LJ; Sucic, S | 2 |
| Macey, DJ; Nader, MA; Porrino, LJ; Smith, HR | 1 |
| Leslie, FM; O'Leary, KT | 1 |
| Ishida, Y; Isobe, K; Shirokawa, T | 1 |
| Horschitz, S; Hummerich, R; Schloss, P | 1 |
| Cleary, L; Docherty, JR | 1 |
| Bailey, SR; Berhane, Y; Elliott, J | 1 |
| Fujiwara, H; Iida, Y; Kanegawa, N; Kawashima, H; Kiyono, Y; Nishimura, H; Saji, H | 1 |
| Murray, K; Murray, M | 1 |
| Bianchi, M; Cavanni, P; Crespi, F; Faedo, S; Heidbreder, CA; Lacroix, LP; Perdona, E; Remelli, R | 1 |
| Altamirano, AV; Benmansour, S; Frazer, A; Gould, GG; Jones, DJ; Morilak, DA; Pardon, MC; Sanchez, TA | 1 |
| Fort, P; Frydman, A; Gallopin, T; Luppi, PH; Rambert, FA | 1 |
| Hume, AS; Kyle, PB; Ordway, GA; Zhu, MY | 1 |
| Steketee, JD; Williams, JM | 1 |
| Candeletti, S; D'Addario, C; Di Benedetto, M; Feliciani, D; Izenwasser, S; Romualdi, P | 1 |
| Caron, MG; Kiss, JP; Vizi, ES; Zsilla, G | 1 |
| Bönisch, H; Brüss, M; Distelmaier, F; Wiedemann, P | 1 |
| Cheetham, S; Jenner, P; Lane, EL | 1 |
| Bylund, DB; Happe, HK; Murrin, LC; Sanders, JD | 1 |
| Miller, GW; Rommelfanger, KS; Weinshenker, D | 1 |
| Barlow, KB; Hipólide, DC; Moreira, KM; Nobrega, JN; Tufik, S; Wilson, AA | 1 |
| Fujita, M; Ghose, S; Halldin, C; Innis, R; Morrison, P; Mozley, PD; Murphy, DL; Schou, M; Uhl, G | 1 |
| Beveridge, TJ; Nader, MA; Porrino, LJ; Smith, HR | 2 |
| Mash, DC; Ouyang, Q; Pablo, J; Qin, Y | 1 |
| Dutta, AK; Reith, ME; Wang, LC | 1 |
| Eriksson, KS; Wisor, JP | 1 |
| Herndon, JG; Killiany, RJ; Luebke, JI; Moore, TL; Moss, MB; Rosene, DL; Schettler, SP | 1 |
| Beard, JL; Beard, Z; Burhans, MS; Dailey, C; Jones, BC; Murray-Kolb, L; Wiesinger, J | 1 |
| Ding, YS; Lin, KS | 1 |
| Biegon, A; Ding, YS; Fowler, J; Lin, KS; Logan, J; Pareto, D | 1 |
| Swant, J; Thompson, AM; Wagner, JJ | 1 |
| Benveniste, H; Carter, P; Ding, YS; Lin, KS; Logan, J | 1 |
| Akaike, A; Katsuki, H | 1 |
| Love, JA; Yi, E | 1 |
| Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH | 1 |
| Barrera, G; Drolet, G; Hernandez, A; Laforest, S; Morilak, DA; Poulin, JF | 1 |
| Lima, L; Manzano, E; Mata, S; Ortiz, T; Urbina, M | 1 |
| Bennett, B; Haughey, HM; Johnson, TE; Kaiser, AL; Sikela, JM; Zahniser, NR | 1 |
| Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF | 1 |
| Greenup, JL; Leverenz, JB; Peskind, ER; Raskind, MA; Szot, P; White, SS | 1 |
| Fukushima, S; Hall, FS; Kobayashi, H; Numachi, Y; Shen, HW; Sora, I; Uhl, GR; Yamashita, M | 1 |
| Beveridge, TJ; Porrino, LJ; Smith, HR | 1 |
| Beard, JL; Burhans, MS; Dailey, C; Jones, BC; Murray-Kolb, LE; Wiesinger, J | 1 |
| Cano, E; Fraiz, N; Orallo, F; Yáñez, M | 1 |
| Billes, SK; Cowley, MA | 2 |
| Mandela, P; Ordway, GA | 1 |
| Amara, SG; Mortensen, OV | 1 |
| Guiry, PJ; Keenan, AK; McBean, GJ; Quinn, ST; Schwab, T | 1 |
| Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Yoshimura, N | 1 |
| Arango, V; Kumar, JSD; Majo, VJ; Mann, JJ; Milak, MS; Parsey, RV; Prabhakaran, J; Severance, AJ; Simpson, NR; Van Heertum, RL | 1 |
| Dutertre, S; Lewis, RJ; Paczkowski, FA; Sharpe, IA | 1 |
| Deutsch, HM; Kim, DI; Schweri, MM; Ye, X | 1 |
| Platt, DM; Rowlett, JK; Spealman, RD | 1 |
| Fukushima, S; Hall, FS; Hata, H; Kobayashi, H; Lesch, KP; Murphy, DL; Numachi, Y; Ohara, A; Sora, I; Uhl, GR; Watanabe, H; Yamashita, M | 1 |
| Blakely, RD; Deecher, DC; Mahaney, PE; Mason, JN; Richmond, RL; Stack, G; Trybulski, E; Winneker, RC | 1 |
| Diniz, PH; Gomez, MV; Gomez, RS; Guatimosim, C; Silva, JH | 1 |
| Bönisch, H; Brüss, M; Gilsbach, R; Löbbe-Werner, S; Muck, A | 1 |
| Beaudin, SA; Booze, RM; Ferris, MJ; Hasselrot, U; Mactutus, CF; Silvers, JM; Strupp, BJ | 1 |
| Kung, HF; Kung, MP; Lakshmi, B; Lieberman, B; Waterhouse, R; Zhao, J | 1 |
| Fujibayashi, Y; Kanegawa, N; Kawashima, H; Kiyono, Y; Kuge, Y; Saji, H; Sugita, T; Ueda, M | 1 |
| Gehlert, DR; Hemrick-Luecke, SK; Shaw, J; Thompson, LK | 1 |
| Bönisch, H; Wenge, B | 2 |
| Baros, AM; Bondi, CO; Lapiz, MD; Morilak, DA; O'Donnell, JM; Zhang, HT; Zhao, Z | 1 |
| Dudczak, R; Ettlinger, DE; Girschele, F; Häusler, D; Kletter, K; Mien, LK; Mitterhauser, M; Sindelar, KM; Ungersböck, J; Viernstein, H; Wadsak, W | 1 |
| Hummel, R; Jacobsen, JP; Mirza, N; Nielsen, EØ; Redrobe, JP; Weikop, P | 1 |
| Babankova, D; Habecker, BA; Kreulen, DL; Novotny, M; Parker, LM; Spitsbergen, JM; Swain, GM; Wehrwein, EA; Wright, AA | 1 |
| Hirano, K; Hotta, Y; Kajiwara, Y; Kobayashi, Y; Sugimoto, Y; Tagawa, N; Yamada, J; Yamada, S | 1 |
| Kritzer, MF; Meyers, B | 1 |
| Babbs, AJ; Chatfield, RE; Krülle, TM; McCormack, JG; Provost, D; Thomas, GH; Widdowson, PS | 1 |
| Hall, FS; Jones, JD; Rice, K; Riley, AL; Uhl, GR | 1 |
| Condron, B; Venton, BJ; Vickrey, TL | 1 |
| Itoh, H; Saito, N; Sakai, N; Takahashi, K; Toyohira, Y; Tsutsui, M; Ueno, S; Yanagihara, N | 1 |
| Bianciotti, LG; Hope, SI; Nabhen, SL; Soria, C; Vatta, MS | 1 |
| Ma, Q; Spealman, RD; Xu, TX; Yao, WD | 1 |
| Franklin, A; Greenup, JL; Leverenz, JB; McMillan, PJ; Raskind, MA; Szot, P; White, SS | 1 |
| Desai, A; Fraser, R; Gnegy, ME; Guptaroy, B; Zhang, M | 1 |
| Ali, S; Dutta, AK; Reith, ME; Zhen, J | 1 |
| Chen, YC; Chen, YW; Chu, CC; Hung, CH; Shao, DZ; Wang, JJ | 1 |
| Beeson, CC; Beeson, GC; Lindsey, CC; Peterson, YK; Schnellmann, RG; Trager, RE; Wills, LP | 1 |
| Carson, RE; Ding, YS; Fan, X; Gallezot, JD; Lin, SF; Mulnix, T; Sherwin, RS; Weinzimmer, D; Yeckel, CW | 1 |
| Arime, Y; Hall, FS; Kasahara, Y; Sora, I; Uhl, GR | 1 |
| Lewis, RJ; Ramu, S; Shaikh, NH; Wang, CI | 1 |
| Chen, YW; Chu, CC; Hung, CH; Kuo, CS; Leung, YM; Wang, JJ | 1 |
| Campos-Torres, A; Haase, J; Malynn, S; Moynagh, P | 1 |
| Horishita, T; Inagaki, H; Kawasaki, T; Obara, G; Sata, T; Takahashi, K; Toyohira, Y; Tsutsui, M; Ueno, S; Yanagihara, N | 1 |
| Hall, FS; Kasahara, Y; Kobayashi, H; Numachi, Y; Sakakibara, Y; Sora, I; Uchiumi, O; Uhl, GR; Yamashita, M; Yoshida, S | 1 |
| Bello, NT; Cunha, PP; Verpeut, JL; Walters, AL | 1 |
| Chung, HW; Jung, KH; Lee, EJ; Lee, KH; Paik, JY; Park, JW | 1 |
| Chen, YW; Chu, CC; Kuo, CS; Leung, YM; Wang, JJ | 1 |
| Bryan-Lluka, LJ; Khamu, TS; Lynagh, T | 1 |
| Chen, HX; Gao, N; Jin, ZL; Li, XR; Li, YF; Tang, Y; Xiong, J; Zhang, JR | 1 |
| Arai, Y; Kaiho, Y; Kawamorita, N; Miyazato, M; Yoshimura, N | 1 |
| Bello, NT; Verpeut, JL; Walters, AL; Yeh, CY | 1 |
| Corradetti, R; Mlinar, B; Stocca, G | 1 |
| Kasahara, Y; Kubo, Y; Sora, I | 1 |
| Satoh, N; Takahashi, K; Toyohira, Y; Yanagihara, N | 1 |
| Gouaux, E; Penmatsa, A; Wang, KH | 1 |
| Privman, E; Venton, BJ | 1 |
| Asano, K; Egawa, S; Furuta, A; Kimura, S; Suzuki, Y; Yoshimura, N | 1 |
| Bermingham, DP; Blakely, RD; Folkes, OM; Hardaway, JA; Jinnah, H; Robinson, SB; Salimando, GJ; Snarrenberg, CL | 1 |
| García-Fuster, MJ; García-Sevilla, JA | 1 |
| Privman Champaloux, E; Pyakurel, P; Venton, BJ | 1 |
| Borbély, Z; Csomó, BK; Gerber, G; Kittel, Á; Varga, G; Vizi, ES | 1 |
| Blakely, RD; Refai, O | 1 |
| Alexander, KS; Miller, LL; Patton, TB; Rodriguez, TR; Sarfo, AN | 1 |
| Anagnostaras, SG; Carmack, SA; Hammam, L; Pantoni, MM | 1 |
| Mizutani, H; Sakakibara, F; Sasaki, E | 1 |
| Chen, M; Jiang, T; Wang, H; Wang, M; Wu, F; Xu, S; Yang, H; Yin, W; Yu, W; Zhang, Y | 1 |
| Hartog, PBR; Heitman, LH; IJzerman, AP; Maresca, G; Rossignoli, A; Scarabottolo, L; Sijben, HJ; Stucchi, L; van Oostveen, WM | 1 |
| Davis, SE; Lin, S; Martinez-Muniz, GA; Porter, KD; Quizon, PM; Strauss, MJ; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J | 1 |
3 review(s) available for fluoxetine and nisoxetine
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
History of antidepressants: successes and failures.
Topics: Albuterol; Animals; Antidepressive Agents; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Dibenzocycloheptenes; Drug Evaluation, Preclinical; Fluoxetine; History, 20th Century; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Psychopharmacology; Receptors, Adrenergic; Receptors, Serotonin; Trazodone; Zimeldine | 1983 |
[Analysis of dopamine transporter knockout mice as an animal model of AD/HD].
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Methylphenidate; Mice; Mice, Knockout | 2013 |
2 trial(s) available for fluoxetine and nisoxetine
| Article | Year |
|---|---|
The effect of nisoxetine (Lilly compound 94939), a potential antidepressant, on biogenic amine uptake in man.
Topics: Adult; Antidepressive Agents; Biogenic Amines; Blood Platelets; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Fluoxetine; Heart Rate; Humans; Male; Norepinephrine; Phenyl Ethers; Propylamines; Serotonin; Tyramine | 1976 |
History of antidepressants: successes and failures.
Topics: Albuterol; Animals; Antidepressive Agents; Brompheniramine; Bupropion; Clinical Trials as Topic; Depressive Disorder; Dibenzocycloheptenes; Drug Evaluation, Preclinical; Fluoxetine; History, 20th Century; Humans; Monoamine Oxidase Inhibitors; Propiophenones; Psychopharmacology; Receptors, Adrenergic; Receptors, Serotonin; Trazodone; Zimeldine | 1983 |
282 other study(ies) available for fluoxetine and nisoxetine
| Article | Year |
|---|---|
Molecular structure of fluoxetine hydrochloride, a highly selective serotonin-uptake inhibitor.
Topics: Animals; Brain; Fluoxetine; Kinetics; Models, Molecular; Molecular Conformation; Norepinephrine; Propylamines; Rats; Serotonin; Serotonin Antagonists; Synaptosomes; X-Ray Diffraction | 1988 |
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Reboxetine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters | 2003 |
From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: synthesis and structure-activity relationship studies.
Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Humans; In Vitro Techniques; Norepinephrine Plasma Membrane Transport Proteins; Propylamines; Rats; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Synaptosomes | 2008 |
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI).
Topics: Adrenergic Uptake Inhibitors; Amines; Atomoxetine Hydrochloride; Binding Sites; Cell Line; Chemistry, Pharmaceutical; Desipramine; Drug Design; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Norepinephrine Plasma Membrane Transport Proteins; Propylamines; Structure-Activity Relationship | 2008 |
Synthesis and structure-activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with a heterocyclic ring constraint.
Topics: Atomoxetine Hydrochloride; Chemistry, Pharmaceutical; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Design; Humans; Indenes; Inhibitory Concentration 50; Microsomes, Liver; Models, Chemical; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Propylamines; Serotonin; Structure-Activity Relationship | 2008 |
Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: a new class of selective norepinephrine reuptake inhibitors.
Topics: Humans; Indoles; Molecular Structure; Neurotransmitter Uptake Inhibitors; Norepinephrine; Stereoisomerism; Structure-Activity Relationship | 2008 |
1-Naphthyl and 4-indolyl arylalkylamines as selective monoamine reuptake inhibitors.
Topics: Amines; Animals; Antidepressive Agents, Second-Generation; Biogenic Monoamines; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Design; Humans; Neurotransmitter Uptake Inhibitors; Protein Binding; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Stereoisomerism | 2009 |
Synthesis and pharmacological evaluation of 4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalenyl amines as triple reuptake inhibitors.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Mice; Naphthalenes; Neurotransmitter Uptake Inhibitors; Norepinephrine; Serotonin | 2011 |
Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor.
Topics: Amines; Animals; Cyclization; Dopamine Uptake Inhibitors; Drug Design; Inhibitory Concentration 50; Mice; Molecular Structure; Norepinephrine; Serotonin; Stereoisomerism | 2011 |
Synthesis and pharmacological characterization of bicyclic triple reuptake inhibitor 3-aryl octahydrocyclopenta[c]pyrrole analogues.
Topics: Animals; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Inhibitory Concentration 50; Isoindoles; Mice; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Pyrroles; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2011 |
Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Lactams; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Pyrrolidinones; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2013 |
Synthesis and biological evaluation of 3-phenethylazetidine derivatives as triple reuptake inhibitors.
Topics: Azetidines; Biological Transport; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Neurotransmitter Uptake Inhibitors; Phenyl Ethers; Plasma Membrane Neurotransmitter Transport Proteins; Serotonin; Structure-Activity Relationship | 2014 |
Exploration of 3-Aminoazetidines as Triple Reuptake Inhibitors by Bioisosteric Modification of 3-α-Oxyazetidine.
Topics: | 2014 |
Amphetamine's locomotor-stimulant and noreprinephrine-releasing effects: evidence for selective antagonism by nisoxetine.
Topics: Animals; Brain Chemistry; Dextroamphetamine; Fluoxetine; Humans; Male; Mice; Mice, Inbred ICR; Motor Activity; Neurotransmitter Agents; Norepinephrine; Phenyl Ethers; Propylamines; Stereotyped Behavior | 1979 |
Modification of PGO activity by specific uptake inhibitors fluoxetine, nisoxetine and LR5182.
Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cats; Decerebrate State; Dimethylamines; Electroencephalography; Female; Fenclonine; Fluoxetine; Geniculate Bodies; Male; Occipital Lobe; Phenyl Ethers; Pons; Propylamines; Reserpine; Time Factors | 1979 |
Depression of REM sleep in cats by nisoxetine, a potential antidepressant drug.
Topics: Animals; Cats; Depression, Chemical; Drug Interactions; Fluoxetine; Levodopa; Male; Nortriptyline; Phenyl Ethers; Propylamines; Serotonin; Sleep, REM; Time Factors | 1976 |
Norepinephrine-stimulated cyclic AMP accumulation in brain slices in vitro after serotonin depletion or chronic administration of selective amine reuptake inhibitors.
Topics: Animals; Brain; Cyclic AMP; Desipramine; Fluoxetine; In Vitro Techniques; Male; Norepinephrine; p-Chloroamphetamine; Phenyl Ethers; Propylamines; Rats; Serotonin | 1977 |
Subsensitivity of the norepinephrine receptor-coupled adenylate cyclase system in brain: effects of nisoxetine versus fluoxetine.
Topics: Adenylyl Cyclases; Animals; Brain; Desipramine; Dihydroalprenolol; Fluoxetine; Male; Norepinephrine; Propylamines; Rats; Receptors, Adrenergic | 1979 |
Nisoxetine antagonism of norepinephrine depletion in brain and heart after alpha-methyl-m-tyrosine administration.
Topics: Animals; Brain Chemistry; Fluoxetine; Male; Metaraminol; Methyltyrosines; Myocardium; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Tyramine | 1979 |
Nisoxetine prevents the 6-hydroxydopamine induced decrease in post-decapitation convulsions.
Topics: Animals; Brain Stem; Cerebral Cortex; Decerebrate State; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Hydroxydopamines; Male; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Seizures; Spinal Cord | 1977 |
Neuronal uptake inhibitors, nisoxetine and fluoxetine on rat vascular contractions.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Drug Interactions; Electric Stimulation; Fluoxetine; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Phenyl Ethers; Portal Vein; Propylamines; Rats; Serotonin | 1977 |
The comparison of fluoxetine and nisoxetine with tricyclic antidepressants in blocking the neurotoxicity of p-chloroamphetamine and 6-hydroxydopamine in the rat brain.
Topics: Amphetamines; Animals; Antidepressive Agents, Tricyclic; Brain; Fluoxetine; Hydroxydopamines; Hypothalamus; In Vitro Techniques; Male; Nerve Endings; Norepinephrine; p-Chloroamphetamine; Phenyl Ethers; Propylamines; Rats; Serotonin | 1976 |
Effect of nisoxetine on uptake of catecholamines in synaptosomes isolated from discrete regions of rat brain.
Topics: Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dopamine; Fluoxetine; Hypothalamus; In Vitro Techniques; Male; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Synaptosomes | 1976 |
dl-N-methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of norepinephrine into rat brain synaptosomes and heart.
Topics: Animals; Biological Transport; Brain; Depression, Chemical; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Heart; Male; Myocardium; Norepinephrine; Phenyl Ethers; Propylamines; Rats; Synaptosomes | 1975 |
Blockade of amine depletion by nisoxetine in comparison to other uptake inhibitors.
Topics: Amines; Animals; Brain; Depression, Chemical; Female; Fluoxetine; Hydroxydopamines; Mice; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; p-Chloroamphetamine; Phenyl Ethers; Propylamines; Serotonin | 1975 |
Effects of repeated administration of desipramine or electroconvulsive shock on norepinephrine uptake sites measured by [3H]nisoxetine autoradiography.
Topics: Animals; Autoradiography; Desipramine; Electroshock; Fluoxetine; Male; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tritium | 1992 |
Characterization of the [3H]-desipramine binding site of the bovine adrenomedullary plasma membrane.
Topics: Adrenal Medulla; Animals; Binding Sites; Carrier Proteins; Cattle; Cell Membrane; Chlorides; Desipramine; Fluoxetine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; Receptors, Drug; Receptors, Neurotransmitter; Sensitivity and Specificity; Sodium; Solubility; Symporters; Tritium | 1992 |
Enhanced sensitivity to the behavioral effects of cocaine after chronic administration of D2-selective dopamine antagonists in the squirrel monkey.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Infusion Pumps; Male; Quipazine; Receptors, Dopamine; Receptors, Dopamine D2; Saimiri; Spiperone | 1992 |
Effect of age on [3H]nisoxetine binding to uptake sites for norepinephrine in the locus coeruleus of humans.
Topics: Adult; Aged; Aging; Autoradiography; Biological Transport; Female; Fluoxetine; Humans; Locus Coeruleus; Male; Middle Aged; Norepinephrine; Regression Analysis; Tritium | 1992 |
[3H]nisoxetine: a radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding.
Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Binding, Competitive; Brain; Cerebral Cortex; Fluoxetine; Kinetics; Male; Maprotiline; Norepinephrine; Oxidopamine; Radioligand Assay; Rats; Rats, Inbred Strains; Stereoisomerism; Tritium | 1992 |
Comparison of dopamine uptake and release in vitro in sheep and rat striatum.
Topics: Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Fluoxetine; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Sheep | 1991 |
High- and low-affinity [3H]desipramine-binding sites in human postmortem brain tissue.
Topics: Adult; Aged; Aged, 80 and over; Animals; Brain; Carrier Proteins; Citalopram; Cricetinae; Desipramine; Female; Fluoxetine; Humans; Male; Middle Aged; Norepinephrine; Radioligand Assay; Receptors, Drug; Receptors, Neurotransmitter | 1990 |
Effects of endothelial cell removal on alpha-adrenoceptor-mediated responses of aortae of pregnant rats.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Azepines; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Female; Fluoxetine; Norepinephrine; Phenylephrine; Pregnancy; Pregnancy, Animal; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction | 1990 |
[3H]nisoxetine: a new radioligand for norepinephrine uptake sites in brain.
Topics: Animals; Benzylamines; Cerebral Cortex; Fluoxetine; Male; Norepinephrine; Premedication; Radioligand Assay; Rats; Rats, Inbred Strains | 1990 |
Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Fluoxetine; In Vitro Techniques; Kinetics; Male; Methylphenidate; Nalidixic Acid; Naphthyridines; Neurotransmitter Uptake Inhibitors; Norepinephrine; Nucleus Accumbens; Olfactory Bulb; Piperazines; Rats; Rats, Inbred Strains | 1990 |
Neural adaptation in imipramine-treated rats processed in forced swim test: assessment of time course, handling, rat strain and amine uptake.
Topics: Adaptation, Physiological; Animals; Behavior, Animal; Cerebral Cortex; Corticosterone; Dihydroalprenolol; Fluoxetine; Hippocampus; Imipramine; Ketanserin; Male; Physical Exertion; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A; Species Specificity; Swimming | 1990 |
Synthesis and regional mouse brain distribution of [11C]nisoxetine, a norepinephrine uptake inhibitor.
Topics: Animals; Brain; Carbon Radioisotopes; Fluoxetine; Isotope Labeling; Mice; Neurotransmitter Uptake Inhibitors; Norepinephrine; Tissue Distribution | 1989 |
Effect of monoamine uptake inhibitors on norepinephrine-stimulated phosphatidylinositol hydrolysis in rat cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Desipramine; Fluoxetine; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Phosphatidylinositols; Prazosin; Rats; Receptors, Adrenergic, alpha | 1989 |
[3H]desipramine binding to rat brain tissue: binding to both noradrenaline uptake sites and sites not related to noradrenaline neurons.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Desipramine; Endopeptidases; Fluoxetine; Male; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1989 |
The effect of amfonelic acid or nisoxetine in combination with morphine on brain-stimulation reward.
Topics: Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Male; Morphine; Nalidixic Acid; Naphthyridines; Norepinephrine; Rats; Rats, Inbred F344; Reward; Sensory Thresholds | 1989 |
Effect of chronic treatment with tricyclic antidepressants upon antinociception induced by intrathecal injection of morphine and monoamines.
Topics: Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Drug Interactions; Fluoxetine; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Time Factors | 1988 |
Of mice and men: the extension of animal models to the clinical evaluation of new drugs.
Topics: Animals; Drug Evaluation; Drug Evaluation, Preclinical; Ergolines; Fluoxetine; Humans; Models, Biological; Pergolide; Pharmacology, Clinical; Rats | 1986 |
Conformational analysis of nisoxetine and fluoxetine, selective inhibitors of norepinephrine and serotonin reuptake: are conformational differences an explanation of neurotransmitter selectivity?
Topics: Chemical Phenomena; Chemistry, Physical; Fluoxetine; Molecular Conformation; Neurotransmitter Agents; Norepinephrine; Phenethylamines; Serotonin; Serotonin Antagonists; Solutions; Thermodynamics | 1986 |
Alpha 1-and alpha 2-adrenoceptors of the circular myometrium from the dioestrous guinea-pig.
Topics: Adrenergic beta-Antagonists; Animals; Diestrus; Estrus; Female; Fluoxetine; Guinea Pigs; Myometrium; Norepinephrine; Phenylephrine; Prazosin; Propanolamines; Receptors, Adrenergic, alpha; Uterine Contraction | 1988 |
Some pharmacological actions of nisoxetine, a bicyclic inhibitor of noradrenaline uptake.
Topics: Animals; Bradykinin; Carbachol; Desipramine; Fluoxetine; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Norepinephrine; Propylamines; Rats; Receptors, Adrenergic, alpha; Reserpine; Vas Deferens; Xylazine | 1985 |
Potentiation of morphine analgesia by D-amphetamine is mediated by norepinephrine and not dopamine.
Topics: Amphetamine; Analgesics; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Electric Stimulation; Escape Reaction; Fluoxetine; Morphine; Nalidixic Acid; Naphthyridines; Norepinephrine; Pain; Reaction Time; Reticular Formation | 1988 |
Characterization of the inhibitory effect of some antidepressant drugs on the outward transport of norepinephrine in the ischemic myocardium.
Topics: Animals; Antidepressive Agents; Biological Transport, Active; Chromatography, High Pressure Liquid; Clonidine; Coronary Disease; Desipramine; Fluoxetine; Heart; Isomerism; Lidocaine; Male; Maprotiline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1988 |
Lack of generalization of nisoxetine with amphetamine in the rat.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Allosteric interaction between the site labeled by [3H]imipramine and the serotonin transporter in human platelets.
Topics: Amitriptyline; Blood Platelets; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorpromazine; Ethylmaleimide; Fluoxetine; Humans; Imipramine; Kinetics; Pyrilamine; Receptors, Serotonin | 1987 |
Evaluation of the role of norepinephrine in the reinforcing effects of psychomotor stimulants in rhesus monkeys.
Topics: Animals; Cocaine; Female; Fluoxetine; Macaca mulatta; Male; Norepinephrine; Prazosin; Psychomotor Performance; Reinforcement, Psychology; Self Administration | 1987 |
Pharmacological analysis of the apomorphine discriminative stimulus in rhesus monkeys.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Cocaine; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Domperidone; Dose-Response Relationship, Drug; Female; Fluoxetine; Macaca mulatta; Male; Physostigmine; Piribedil; Quipazine; Sodium Chloride | 1987 |
The release of endogenous dopamine from rat striatum during incubation in vitro.
Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Corpus Striatum; Dopamine; Fluoxetine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Nomifensine; Potassium; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Prazosin: effect on psychomotor-stimulant cues and locomotor activity in mice.
Topics: Amphetamine; Animals; Cocaine; Cues; Discrimination, Psychological; Fluoxetine; Male; Mice; Mice, Inbred ICR; Motor Activity; Pimozide; Prazosin; Propranolol; Stereotyped Behavior | 1985 |
Responses of the melanophores of the fiddler crab, Uca pugilator, to drugs affecting noradrenergic neurotransmission: further evidence for norepinephrine as a neurotransmitter triggering release of melanin-dispersing hormone.
Topics: Adrenergic beta-Antagonists; Animals; Brachyura; Fluoxetine; Hormones; Male; Melanins; Melanophores; Neurotransmitter Agents; Norepinephrine; Peptides | 1981 |
A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Fluoxetine; Hypothalamus; Kinetics; Male; Neurotransmitter Agents; Norepinephrine; Propylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Synaptosomes | 1982 |
Modification of alpha-adrenoceptor agonist antinociceptive activity by nisoxetine: a selective inhibitor of noradrenergic uptake.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Mice; Norepinephrine; Propylamines; Xylazine | 1984 |
Cobaltous chloride-induced hypothermia in mice III: effect of pretreatment with 5-hydroxytryptaminergic agents.
Topics: Animals; Body Temperature; Brain Chemistry; Cobalt; Fenclonine; Fluoxetine; Male; Mice; p-Chloroamphetamine; Serotonin; Serotonin Antagonists; Time Factors | 1983 |
Antagonism by tomoxetine of the depletion of norepinephrine and epinephrine in rat brain by alpha-methyl-m-tyrosine.
Topics: Animals; Antidepressive Agents; Biological Transport; Brain Chemistry; Epinephrine; Fluoxetine; Male; Methyltyrosines; Norepinephrine; Propylamines; Rats | 1983 |
Nisoxetine and amphetamine share discriminative stimulus properties in mice.
Topics: Amphetamine; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Fluoxetine; Male; Mice; Mice, Inbred ICR; Premedication; Propylamines; Taste | 1983 |
Effects of norepinephrine and serotonin uptake inhibitors on the schedule-controlled behavior of the pigeon.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Columbidae; Conditioning, Operant; Desipramine; Doxepin; Fluoxetine; Iprindole; Male; Norepinephrine; Protriptyline; Reinforcement Schedule; Serotonin Antagonists | 1984 |
Effects of chronic treatment with antidepressants on aggressiveness induced by clonidine in mice.
Topics: Aggression; Animals; Antidepressive Agents; Citalopram; Clonidine; Drug Interactions; Fluoxetine; Flupenthixol; Fluvoxamine; Humans; Male; Mice; Oximes; Pizotyline; Propylamines; Stereoisomerism | 1982 |
Effects of norepinephrine and 5-hydroxytryptamine reuptake inhibitors on electrically-induced spinal cord seizures in rats.
Topics: Animals; Benzofurans; Citalopram; Desipramine; Electric Stimulation; Female; Fluoxetine; Norepinephrine; Propylamines; Rats; Seizures; Serotonin Antagonists; Spinal Cord | 1980 |
Clonidine analgesia and suppression of operant responding: dissociation of mechanism.
Topics: Analgesics; Animals; Clonidine; Conditioning, Operant; Drug Interactions; Fluoxetine; Male; Norepinephrine; Phenoxybenzamine; Rats; Xylazine; Yohimbine | 1981 |
Effects of acutely and chronically administered antidepressants on the clonidine-induced decrease in rat brain 3-methoxy-4-hydroxyphenylethylene-glycol sulphate content.
Topics: Animals; Antidepressive Agents; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Clonidine; Desipramine; Fluoxetine; Glycols; Iprindole; Male; Methoxyhydroxyphenylglycol; Mianserin; Rats | 1981 |
Monoaminergic mechanisms and experimental cataplexy.
Topics: Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Cataplexy; Dogs; Female; Fluoxetine; Haloperidol; Humans; Male; Methylphenidate; Monoamine Oxidase Inhibitors; Physostigmine; Pimozide; Propranolol; Sleep, REM; Sodium Oxybate | 1981 |
Effects of monoamine reuptake inhibitors on cocaine self-administration in rats.
Topics: Animals; Biogenic Monoamines; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Injections, Intravenous; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Reward; Self Administration | 1995 |
(R)-thionisoxetine, a potent and selective inhibitor of central and peripheral norepinephrine uptake.
Topics: Animals; Carrier Proteins; Cerebral Cortex; Fluoxetine; Hypothalamus; Isomerism; Male; Metaraminol; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Peripheral Nervous System; Rats; Rats, Sprague-Dawley; Serotonin; Symporters; Synaptosomes; Urethra | 1995 |
Comparison of (R)-[3H]tomoxetine and (R/S)-[3H]nisoxetine binding in rat brain.
Topics: Animals; Atomoxetine Hydrochloride; Autoradiography; Binding Sites; Brain; Citalopram; Desipramine; Fluoxetine; Male; Norepinephrine; Propylamines; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tritium | 1995 |
Binding of bromine-substituted analogs of methylphenidate to monoamine transporters.
Topics: Animals; Binding, Competitive; Bromine; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Mice; Microdialysis; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tomography, Emission-Computed, Single-Photon | 1994 |
Monoamine uptake inhibitors alter cocaine pharmacokinetics.
Topics: Animals; Biotransformation; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Interactions; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley | 1993 |
Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.
Topics: Animals; Biogenic Monoamines; Citalopram; Cocaine; Desipramine; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Lidocaine; Ligands; Male; Microdialysis; Movement; Norepinephrine; Piperazines; Rats; Serotonin; Tetrodotoxin; Ventral Tegmental Area | 1994 |
Effect of repeated novel stressors on depressive behavior and brain norepinephrine receptor system in Sprague-Dawley and Wistar Kyoto (WKY) rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Body Weight; Brain; Carrier Proteins; Depression; Dioxanes; Fluoxetine; Idazoxan; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pindolol; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptors, Adrenergic; Species Specificity; Stress, Psychological; Swimming; Symporters | 1994 |
Facilitatory and inhibitory effects of selective norepinephrine reuptake inhibitors on hypogastric nerve-evoked urethral contractions in the cat: a prominent role of urethral beta-adrenergic receptors.
Topics: Animals; Atomoxetine Hydrochloride; Cats; Dose-Response Relationship, Drug; Female; Fluoxetine; Muscle Contraction; Norepinephrine; Propranolol; Propylamines; Receptors, Adrenergic, beta; Urethra | 1994 |
Inhibition of spinal noradrenaline uptake in rats by the centrally acting analgesic tramadol.
Topics: Animals; Fluoxetine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Spinal Cord; Stereoisomerism; Synaptosomes; Tramadol; Zimeldine | 1994 |
In vitro effects of cocaine, lidocaine and monoamine uptake inhibitors on lymphocyte proliferative responses.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cocaine; Desipramine; Fluoxetine; Lidocaine; Lymphocyte Activation; Male; Mitogens; Monoamine Oxidase Inhibitors; Nomifensine; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1994 |
A time course of altered thyroid states on the noradrenergic system in rat brain by quantitative autoradiography.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Animals; Autoradiography; Body Weight; Brain Chemistry; Dioxanes; Fluoxetine; Idazoxan; Male; Norepinephrine; Pindolol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Presynaptic; Thyroid Gland; Thyroidectomy; Time Factors | 1994 |
Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter.
Topics: Binding Sites; Carrier Proteins; Chlorides; Cocaine; Fluoxetine; Humans; In Vitro Techniques; Kinetics; Microvilli; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Placenta; Sodium; Symporters | 1993 |
Cocaine: cardiovascular effects in relation to inhibition of peripheral neuronal monoamine uptake and central stimulation of the sympathoadrenal system.
Topics: Adrenal Medulla; Animals; Biological Transport; Blood Pressure; Catecholamines; Chlorisondamine; Cocaine; Desipramine; Fluoxetine; Heart Rate; Male; Norepinephrine; Oxidopamine; Peripheral Nervous System; Propanolamines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Time Factors | 1993 |
Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites.
Topics: Animals; Atomoxetine Hydrochloride; Binding Sites; Desipramine; Fluoxetine; Kinetics; Ligands; Male; Nerve Tissue Proteins; Norepinephrine; Piperazines; Propylamines; Prosencephalon; Rats; Rats, Sprague-Dawley | 1993 |
Norepinephrine transporter sites are decreased in the locus coeruleus in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Autoradiography; Carrier Proteins; Female; Fluoxetine; Humans; Locus Coeruleus; Male; Middle Aged; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Tissue Distribution | 1993 |
[3H]Nisoxetine binding sites in the cat brain: an autoradiographic study.
Topics: Animals; Autoradiography; Binding Sites; Brain; Cats; Female; Fluoxetine; Male; Norepinephrine; Tissue Distribution; Tritium | 1995 |
[3H]nisoxetine--a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments.
Topics: Animals; Antidepressive Agents; Binding, Competitive; Fluoxetine; Frontal Lobe; Kinetics; Male; Norepinephrine; Radioligand Assay; Rats; Rats, Sprague-Dawley | 1996 |
Synthesis of 3 beta-aryl-8-azabicyclo[3.2.1]octanes with high binding affinities and selectivities for the serotonin transporter site.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Frontal Lobe; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters; Tropanes | 1996 |
Nonexocytotic noradrenaline release and ventricular fibrillation in ischemic rat hearts.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Desipramine; Exocytosis; Fluoxetine; In Vitro Techniques; Male; Myocardial Ischemia; Norepinephrine; Rats; Rats, Wistar; Ventricular Fibrillation | 1995 |
Synthesis and transporter binding properties of 3 beta-(4'-alkyl-, 4'-alkenyl-, and 4'-alkynylphenyl)nortropane-2 beta-carboxylic acid methyl esters: serotonin transporter selective analogs.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine; Nortropanes; Paroxetine; Radioligand Assay; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes | 1996 |
Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline.
Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan | 1996 |
3 alpha-(4'-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters: novel ligands with high affinity and selectivity at the dopamine transporter.
Topics: Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Paroxetine; Serotonin; Stereoisomerism; Structure-Activity Relationship | 1996 |
Regulation of sympathetic presynaptic components in rat left ventricle during ligation of abdominal aorta.
Topics: Animals; Aorta, Abdominal; Binding Sites; Carrier Proteins; Fluoxetine; Hypertension; Ligation; Male; Methyltyrosines; Myocardium; Neuropeptide Y; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Symporters; Time Factors; Ventricular Function, Left | 1996 |
Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects.
Topics: Administration, Oral; Animals; Autoradiography; Biological Transport; Brain; Carrier Proteins; Cocaine; Drug Administration Schedule; Female; Fluoxetine; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Substance Withdrawal Syndrome; Substance-Related Disorders; Symporters; Time Factors; Tritium | 1996 |
The stimulatory and inhibitory components of cocaine's actions on the 5-HTP-induced 5-HT2A receptor response.
Topics: 1-Naphthylamine; 5-Hydroxytryptophan; Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline | 1996 |
Down-regulation of norepinephrine transporters on PC12 cells by transporter inhibitors.
Topics: Animals; Antidepressive Agents; Binding Sites; Carrier Proteins; Cell Count; Cell Survival; Desipramine; Down-Regulation; Fluoxetine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; Symporters; Therapeutic Irrigation | 1997 |
Gender-related differences exist in cortical [3H]nisoxetine binding and are not affected by prenatal morphine exposure.
Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Female; Fluoxetine; Hypothalamus; Kinetics; Male; Morphine; Nerve Endings; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Characteristics | 1997 |
Control of endogenous norepinephrine release in the hypothalamus of male rats changes over adolescent development.
Topics: Adrenergic alpha-Antagonists; Age Factors; Animals; Cells, Cultured; Evoked Potentials; Fluoxetine; Hypothalamus; Idazoxan; Male; Norepinephrine; Potassium; Rats; Rats, Inbred Strains | 1997 |
Pharmacology and distribution of norepinephrine transporters in the human locus coeruleus and raphe nuclei.
Topics: Adult; Age Factors; Aged; Carrier Proteins; Female; Fluoxetine; Humans; Locus Coeruleus; Male; Middle Aged; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Raphe Nuclei; Symporters; Synapses | 1997 |
Placental norepinephrine transporter development in the ovine fetus.
Topics: Animals; Binding Sites; Biological Transport; Carrier Proteins; Female; Fetus; Fluoxetine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Placenta; Pregnancy; Sheep; Symporters | 1997 |
Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective compound
Topics: Animals; Brain; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Nortropanes; Paroxetine; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters | 1997 |
An affinity-modulating site on neuronal monoamine transport proteins.
Topics: 1-Naphthylamine; Animals; Binding Sites; Biogenic Monoamines; Cerebral Cortex; Citalopram; Corpus Striatum; Female; Fluoxetine; In Vitro Techniques; Kinetics; Neurons; Piperazines; Rats; Receptors, Neurotransmitter; Sertraline; Stereoisomerism | 1997 |
Comparison of the effects of sibutramine and other monoamine reuptake inhibitors on food intake in the rat.
Topics: Animals; Cyclobutanes; Cyclohexanols; Eating; Fenfluramine; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Obesity; Rats; Rats, Sprague-Dawley; Venlafaxine Hydrochloride | 1997 |
Effects of nisoxetine, a selective noradrenaline transporter blocker, on sleep in rats.
Topics: Animals; Carrier Proteins; Dose-Response Relationship, Drug; Fluoxetine; Male; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Wistar; Sleep; Symporters | 1997 |
Effect of acute or repeated stress on behavior and brain norepinephrine system in Wistar-Kyoto (WKY) rats.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Autoradiography; Behavior, Animal; Chronic Disease; Fluoxetine; Iodine Radioisotopes; Limbic System; Male; Norepinephrine; Pindolol; Rats; Rats, Inbred WKY; Restraint, Physical; Stress, Physiological; Tritium | 1997 |
Reduced levels of norepinephrine transporters in the locus coeruleus in major depression.
Topics: Adult; Aged; Carrier Proteins; Depressive Disorder; Female; Fluoxetine; Humans; Locus Coeruleus; Male; Melanins; Middle Aged; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Suicide; Symporters | 1997 |
2'-Substitution of cocaine selectively enhances dopamine and norepinephrine transporter binding.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Symporters | 1997 |
Norepinephrine transporters in rat placenta labeled with [3H]nisoxetine.
Topics: Animals; Autoradiography; Binding, Competitive; Carrier Proteins; Fluoxetine; Neurotransmitter Uptake Inhibitors; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Placenta; Rats; Rats, Sprague-Dawley; Symporters | 1998 |
Characterization of [3H]nisoxetine binding in rat vas deferens membranes: modulation by sigma and PCP ligands.
Topics: Animals; Binding, Competitive; Carrier Proteins; Fluoxetine; Male; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Receptors, sigma; Sodium; Symporters; Vas Deferens | 1998 |
Discriminative stimulus properties of cocaine: enhancement by monoamine reuptake blockers.
Topics: Animals; Cocaine; Desipramine; Discrimination Learning; Dopamine; Dose-Response Relationship, Drug; Fluoxetine; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin; Ventral Tegmental Area | 1998 |
Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Desipramine; Drug Interactions; Epilepsy; Female; Fluoxetine; Idazoxan; Methoxamine; Microinjections; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission | 1998 |
Proarrhythmic effects of pinacidil are partially mediated through enhancement of catecholamine release in isolated perfused guinea-pig hearts.
Topics: Adenosine Triphosphate; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Epinephrine; Fluoxetine; Glyburide; Guanidines; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Methoxamine; Myocardial Reperfusion Injury; Myocardium; Nadolol; Norepinephrine; Perfusion; Pinacidil; Potassium Channels; Tyramine | 1998 |
Down-regulation of the human norepinephrine transporter in intact 293-hNET cells exposed to desipramine.
Topics: Adrenergic Uptake Inhibitors; Blotting, Western; Carrier Proteins; Cell Line; Desipramine; Embryo, Mammalian; Fluoxetine; Humans; Kidney; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; RNA, Messenger; Symporters | 1998 |
Cocaine and selective monoamine uptake blockers (sertraline, nisoxetine, and GBR 12935) prevent the d-fenfluramine-induced head-twitch response in mice.
Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Fenfluramine; Fluoxetine; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1998 |
Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters.
Topics: Animals; Antidepressive Agents, Second-Generation; Binding, Competitive; Brain; Carrier Proteins; Cyclohexanols; Fluoxetine; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Symporters; Venlafaxine Hydrochloride | 1998 |
Voltammetric studies on mechanisms of dopamine efflux in the presence of substrates and cocaine from cells expressing human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Carrier Proteins; Cocaine; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Fluoxetine; Humans; Ionophores; Kinetics; LLC-PK1 Cells; Membrane Potentials; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ouabain; Phenethylamines; Psychotropic Drugs; Swine; Symporters; Time Factors; Tyramine; Valinomycin; Veratridine | 1998 |
Elevation of extracellular cortical noradrenaline may contribute to the antidepressant activity of zotepine: an in vivo microdialysis study in freely moving rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Calcium; Desipramine; Dibenzothiepins; Extracellular Space; Fluoxetine; Frontal Lobe; Kinetics; Male; Microdialysis; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley | 1998 |
Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.
Topics: Binding Sites; Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Enzyme Activation; Fluoxetine; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Kinase C; Symporters; Tetradecanoylphorbol Acetate | 1998 |
Modulation of cocaine-induced motor activity in the rat by opioid receptor agonists.
Topics: Animals; Cisterna Magna; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Injections; Male; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors | 1998 |
Characterization of both dopamine uptake systems in rat striatal slices by specific pharmacological tools.
Topics: Animals; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; In Vitro Techniques; Male; Motor Activity; Norepinephrine; Nortropanes; Oxidopamine; Piperazines; Rats; Rats, Wistar; Reserpine; Selective Serotonin Reuptake Inhibitors; Tetrabenazine | 1998 |
Cold exposure regulates the norepinephrine uptake transporter in rat brown adipose tissue.
Topics: Adipose Tissue, Brown; Animals; Carrier Proteins; Cold Temperature; Feeding Behavior; Fluoxetine; In Vitro Techniques; Kinetics; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Reference Values; Symporters; Time Factors | 1999 |
Castration differentially alters [3H]nisoxetine binding to norepinephrine uptake sites in olfactory bulb and frontal cortex of male rats.
Topics: Animals; Fluoxetine; Frontal Lobe; Kinetics; Male; Norepinephrine; Olfactory Bulb; Orchiectomy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Synaptosomes; Testosterone | 1999 |
Pharmacological profile of neuroleptics at human monoamine transporters.
Topics: Antipsychotic Agents; Carrier Proteins; Cell Line; Chlorpromazine; Cocaine; Dibenzazepines; Dibenzothiepins; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Imipramine; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Pimozide; Piperazines; Protein Binding; Radioligand Assay; Recombinant Fusion Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Thiazoles; Triflupromazine; Tritium | 1999 |
Modulation of external pancreatic secretion by endogenous norepinephrine: study with a norepinephrine uptake blocker in the rat.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Deoxyglucose; Electric Stimulation; Fluoxetine; Idazoxan; Kinetics; Male; Norepinephrine; Pancreas; Prazosin; Propranolol; Rats; Rats, Wistar; Vagus Nerve; Yohimbine | 1999 |
Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type.
Topics: Carrier Proteins; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Iodine Radioisotopes; Kidney; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pharmaceutical Preparations; Protein Binding; Radioligand Assay; Recombinant Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Symporters | 1999 |
Thermogenic effects of sibutramine and its metabolites.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antidepressive Agents, Second-Generation; Appetite Depressants; Atenolol; Body Temperature; Body Temperature Regulation; Chlorisondamine; Cyclobutanes; Dose-Response Relationship, Drug; Female; Fluoxetine; Ganglionic Blockers; Glucose; Oxygen Consumption; Phenethylamines; Propanolamines; Rats; Rats, Wistar | 1999 |
Assessment of the adrenergic effects of orphenadrine in rat vas deferens.
Topics: Adrenergic Agents; Animals; Atropine; Binding, Competitive; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Epididymis; Fluoxetine; In Vitro Techniques; Ligands; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Norepinephrine; Orphenadrine; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Vas Deferens | 1999 |
Persistently increased density of serotonin transporters in the frontal cortex of rats treated with fluoxetine during early juvenile life.
Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Carrier Proteins; Fluoxetine; Growth; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Prefrontal Cortex; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 1999 |
Pharmacological characterization of dopamine transport in cultured rat astrocytes.
Topics: Animals; Astrocytes; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Kinetics; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Sodium; Symporters; Zimeldine | 1999 |
Effect of sumatriptan on external pancreatic secretion and its interaction with endogenous norepinephrine in the rat.
Topics: Acetylcholine; Animals; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electric Stimulation; Fluoxetine; Male; Norepinephrine; Pancreas; Pancreatic Fistula; Rats; Rats, Wistar; Serotonin Receptor Agonists; Sumatriptan; Vagus Nerve | 1999 |
Desipramine treatment decreases 3H-nisoxetine binding and norepinephrine transporter mRNA in SK-N-SHSY5Y cells.
Topics: Adrenergic Uptake Inhibitors; Carrier Proteins; Desipramine; Fluoxetine; Humans; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Symporters; Tumor Cells, Cultured | 1999 |
Effects of serine mutations in transmembrane domain 7 of the human norepinephrine transporter on substrate binding and transport.
Topics: Animals; Biological Transport; Carrier Proteins; COS Cells; Dopamine; Electrodes; Fluoxetine; Humans; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Protein Structure, Tertiary; Radioligand Assay; Serine; Symporters; Tritium; Tyramine | 1999 |
Synthesis and characterization of fluorescent ligands for the norepinephrine transporter: potential neuroblastoma imaging agents.
Topics: Carrier Proteins; Cocaine; Dihydropyridines; Fluorescent Dyes; Fluoxetine; Guanidines; Humans; Isoxazoles; Ligands; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Structure-Activity Relationship; Symporters; Tumor Cells, Cultured | 1999 |
Nicotinic acetylcholine receptor antagonistic activity of monoamine uptake blockers in rat hippocampal slices.
Topics: Animals; Culture Techniques; Desipramine; Electric Stimulation; Electrophysiology; Fluoxetine; Hippocampus; Male; Neurons; Neurotransmitter Uptake Inhibitors; Nicotinic Antagonists; Nomifensine; Norepinephrine; Rats; Rats, Wistar; Receptors, Nicotinic; Sodium Channels; Superior Cervical Ganglion; Tetrodotoxin | 1999 |
Activation and desensitization by cyclic antidepressant drugs of alpha2-autoreceptors, alpha2-heteroreceptors and 5-HT1A-autoreceptors regulating monamine synthesis in the rat brain in vivo.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Autoreceptors; Brain; Carboxy-Lyases; Cerebral Cortex; Desipramine; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hippocampus; Male; Norepinephrine; Protriptyline; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Tryptophan; Tyrosine; Zimeldine | 1999 |
Continuous infusion of selective dopamine uptake inhibitors or cocaine produces time-dependent changes in rat locomotor activity.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Dopamine Uptake Inhibitors; Drug Tolerance; Fluoxetine; Infusion Pumps, Implantable; Male; Monoamine Oxidase Inhibitors; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Time Factors | 1999 |
Cocaine up-regulates norepinephrine transporter binding in the rat placenta.
Topics: Animals; Body Weight; Brain Chemistry; Carrier Proteins; Cell Membrane; Cocaine; Eating; Female; Fluoxetine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Placenta; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Symporters; Up-Regulation | 1999 |
Regional brain distribution of noradrenaline uptake sites, and of alpha1-alpha2- and beta-adrenergic receptors in PCD mutant mice: a quantitative autoradiographic study.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Basal Ganglia; Brain Stem; Cerebral Cortex; Disease Models, Animal; Female; Fluoxetine; Hypothalamus; Idazoxan; Limbic System; Mice; Mice, Neurologic Mutants; Norepinephrine; Prazosin; Propanolamines; Purkinje Cells; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Spinocerebellar Degenerations; Thalamus; Tritium | 1999 |
Nitrogen-based drugs are not essential for blockade of monoamine transporters.
Topics: Animals; Binding Sites; Carrier Proteins; Citalopram; Cocaine; COS Cells; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Humans; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nitrogen; Norepinephrine; Putamen; Radioligand Assay | 1996 |
Relationships among dopamine transporter affinities and cocaine-like discriminative-stimulus effects.
Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Nerve Tissue Proteins; Psychomotor Performance; Putamen; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Tritium; Zimeldine | 2000 |
Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood.
Topics: Aging; Animals; Brain; Brain Stem; Carrier Proteins; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Fluoxetine; Frontal Lobe; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Piperazines; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters; Tritium | 2000 |
A comparison of the acute effects of zotepine and other antipsychotics on rat cortical dopamine release, in vivo.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Dibenzothiepins; Dopamine; Fluoxetine; Frontal Lobe; Haloperidol; Male; Microdialysis; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin | 2000 |
Noradrenergic lesion antagonizes desipramine-induced adaptation of NMDA receptors.
Topics: Adaptation, Physiological; Animals; Antidepressive Agents, Tricyclic; Benzylamines; Cerebral Cortex; Desipramine; Fluoxetine; Glycine; Kynurenic Acid; Male; Mice; Norepinephrine; Receptors, N-Methyl-D-Aspartate | 2000 |
Dopamine transporter synthesis and degradation rate in rat striatum and nucleus accumbens using RTI-76.
Topics: Animals; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Injections, Intraventricular; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Piperazines; Protein Binding; Rats; Rats, Sprague-Dawley; Symporters; Tropanes | 2000 |
Paroxetine binding to the rat norepinephrine transporter in vivo.
Topics: Animals; Biological Transport, Active; Calibration; Carrier Proteins; Chromatography, High Pressure Liquid; Fluoxetine; In Vitro Techniques; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Spectrophotometry, Ultraviolet; Symporters | 2000 |
Loss of noradrenaline transporter sites in frontal cortex of rats with acute (ischemic) liver failure.
Topics: Acute Disease; Ammonia; Animals; Brain Edema; Carrier Proteins; Fluoxetine; Frontal Lobe; Hepatic Encephalopathy; Ischemia; Liver; Liver Failure; Male; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Symporters; Thalamus | 2001 |
Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study.
Topics: Animals; Antidepressive Agents; Autoradiography; Brain Chemistry; Carrier Proteins; Citalopram; Cyclohexanols; Desipramine; Fluoxetine; Gene Expression Regulation; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereotaxic Techniques; Symporters; Trimipramine; Venlafaxine Hydrochloride | 2001 |
Regulation of the human norepinephrine transporter by cocaine and amphetamine.
Topics: Amphetamine; Animals; Carrier Proteins; Cells, Cultured; Cocaine; Fluoxetine; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; PC12 Cells; Rats; RNA, Messenger; Symporters | 2000 |
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Heart Failure; Heart Ventricles; Hypertrophy; In Vitro Techniques; Male; Membranes; Monocrotaline; Norepinephrine; Piperazines; Rats; Rats, Wistar; Tritium | 2000 |
Early methylphenidate administration to young rats causes a persistent reduction in the density of striatal dopamine transporters.
Topics: Animals; Brain Chemistry; Carrier Proteins; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Mesencephalon; Methylphenidate; Neostriatum; Nerve Tissue Proteins; Paroxetine; Piperazines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors | 2001 |
Interaction of local anaesthetic agents with the endogenous norepinephrine transporter in SH-SY5Y human neuroblastoma cells.
Topics: Anesthetics, Local; Carrier Proteins; Fluoxetine; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Tumor Cells, Cultured | 2001 |
Nisoxetine infusion into the olfactory bulb enhances the capacity for male rats to identify conspecifics.
Topics: Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Drug Interactions; Female; Fluoxetine; Hierarchy, Social; Male; Norepinephrine; Olfactory Bulb; Phentolamine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Recognition, Psychology; Sexual Behavior, Animal; Smell; Social Facilitation | 2001 |
Characterization of antidepressant-like effects of p-synephrine stereoisomers.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Anesthetics, Local; Animals; Antidepressive Agents; Cerebral Cortex; Fluoxetine; Hindlimb Suspension; Hypothermia; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Reserpine; Stereoisomerism; Swimming; Synephrine; Tetrodotoxin; Tritium | 2001 |
Functional characterization of the splicing variants of human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Alternative Splicing; Animals; Binding, Competitive; Cell Compartmentation; Cell Membrane; Cell Nucleus; COS Cells; Fluoxetine; Humans; Immunohistochemistry; Nervous System; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Isoforms; Radioligand Assay; Symporters; Synaptic Transmission | 2001 |
Rate-independent inhibition by norepinephrine of 5-HT release from the somadendritic region of serotonergic neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Dendrites; Dose-Response Relationship, Drug; Electric Stimulation; Feedback; Fluoxetine; Mesencephalon; Methiothepin; Neural Inhibition; Neurons; Norepinephrine; Phenylephrine; Prazosin; Rabbits; Raphe Nuclei; Receptors, Adrenergic; Serotonin; Serotonin Antagonists; Yohimbine | 2001 |
Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells.
Topics: Blotting, Western; Calcium; Cell Line; Fluoxetine; Humans; Hypoglycemic Agents; Indicators and Reagents; Insulin; Mitogen-Activated Protein Kinases; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Radioligand Assay; Receptors, Muscarinic; Signal Transduction; Symporters | 2001 |
Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology.
Topics: Amino Acid Substitution; Animals; Biological Transport; Chlorocebus aethiops; Cocaine; Codon; COS Cells; Desipramine; Dopamine; Fluoxetine; Humans; Kinetics; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Structure-Activity Relationship; Symporters; Transfection; Tyrosine | 2001 |
Protein kinase C and the sub-sensitivity and sub-reactivity of the diabetic rat prostate gland to noradrenaline.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Fluoxetine; Immunohistochemistry; Indoles; Male; Maleimides; Methoxamine; Muscarinic Antagonists; Naphthalenes; Norepinephrine; Prazosin; Propranolol; Prostate; Protein Kinase C; Rats; Rats, Wistar | 2002 |
Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines.
Topics: Animals; Brain; Brain Chemistry; Caudate Nucleus; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Frontal Lobe; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Piperazines; Symporters; Synaptosomes | 2002 |
Biochemical and autoradiographic studies of the central noradrenergic system in dystonia musculorum mutant mice.
Topics: Animals; Autoradiography; Brain Chemistry; Cerebellum; Chromatography, High Pressure Liquid; Dystonia Musculorum Deformans; Fluoxetine; Male; Mice; Mice, Neurologic Mutants; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Spinal Cord; Symporters; Tritium | 2002 |
Pharmacological properties of the naturally occurring Ala(457)Pro variant of the human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Substitution; Animals; Binding Sites; Cocaine; COS Cells; Desipramine; Dopamine Uptake Inhibitors; Fluoxetine; Green Fluorescent Proteins; Humans; Luminescent Proteins; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Isoforms; Symporters; Transfection | 2002 |
Identification and functional characterization of the novel isoforms of bovine norepinephrine transporter produced by alternative splicing.
Topics: Alternative Splicing; Animals; Cattle; Cell Membrane; Central Nervous System; COS Cells; DNA, Complementary; Exons; Fluoxetine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Presynaptic Terminals; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Symporters; Synaptic Transmission | 2002 |
Characterization of cocaine and antidepressant-sensitive norepinephrine transporters in rat placental trophoblasts.
Topics: Animals; Antidepressive Agents; Binding Sites; Cells, Cultured; Cocaine; Dopamine Uptake Inhibitors; Female; Fluoxetine; Membrane Potentials; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Symporters; Trophoblasts | 2002 |
Chronic clozapine, but not haloperidol, treatment affects rat brain vesicular monoamine transporter 2.
Topics: Animals; Antipsychotic Agents; Binding Sites; Biological Transport; Brain; Brain Chemistry; Clozapine; Drug Administration Schedule; Fluoxetine; Haloperidol; In Situ Hybridization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neuropeptides; Paroxetine; Piperazines; Rats; Tetrabenazine; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins | 2002 |
Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter.
Topics: Amino Acid Substitution; Animals; Binding, Competitive; Cell Line; Cocaine; Conserved Sequence; COS Cells; Desipramine; Dopamine Agents; Female; Fluoxetine; Gene Expression; Glutamic Acid; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Ovary; Sequence Homology, Amino Acid; Sodium; Structure-Activity Relationship; Symporters; Transfection | 2002 |
Castration increases nisoxetine-evoked norepinephrine levels in vivo within the olfactory bulb of male rats.
Topics: Animals; Atomoxetine Hydrochloride; Extracellular Space; Fluoxetine; Male; Microdialysis; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Olfactory Bulb; Orchiectomy; Presynaptic Terminals; Propylamines; Rats; Rats, Sprague-Dawley; Reproduction; Sexual Behavior, Animal; Smell; Symporters; Testosterone; Up-Regulation | 2002 |
Inhibition of vesicular uptake of monoamines by hyperforin.
Topics: Animals; Anti-Bacterial Agents; Biogenic Monoamines; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Fluoxetine; Hypericum; Male; Neurotransmitter Uptake Inhibitors; Phloroglucinol; Piperazines; Plant Extracts; Prosencephalon; Rats; Synaptosomes; Terpenes | 2002 |
Enhanced amphetamine-mediated dopamine release develops in PC12 cells after repeated amphetamine treatment.
Topics: Amphetamine; Animals; Dopamine; Fluoxetine; Nerve Growth Factor; PC12 Cells; Rats | 2002 |
Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions.
Topics: Animals; Carrier Proteins; Cocaine; Conditioning, Psychological; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Gene Deletion; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neuropeptides; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Symporters; Vesicular Biogenic Amine Transport Proteins | 2002 |
S-[18F]fluoromethyl-(+)-McN5652, a PET tracer for the serotonin transporter: evaluation in rats.
Topics: Animals; Autoradiography; Brain; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Fluoxetine; Isoquinolines; Male; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Radioactive Tracers; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Symporters; Tomography, Emission-Computed | 2003 |
Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.
Topics: Adolescent; Adult; Arginine; Calcium; Calcium Channel Blockers; Cerebral Cortex; Dihydro-beta-Erythroidine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Ganglionic Stimulants; Guanylate Cyclase; Humans; In Vitro Techniques; Indazoles; Male; Mecamylamine; Methylene Blue; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nicotine; Nicotinic Antagonists; Nitrendipine; Nitric Oxide Synthase; Norepinephrine; omega-Conotoxin GVIA; Oxadiazoles; Purinones; Quinoxalines; Tetrodotoxin; Tritium; Tubocurarine | 2002 |
Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.
Topics: Animals; Binding, Competitive; Cell Membrane; Disease Models, Animal; Eye Proteins; Fluoxetine; G-Protein-Coupled Receptor Kinase 1; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Size; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Rhodopsin; Symporters | 2002 |
The role of the conserved GXXXRXG motif in the expression and function of the human norepinephrine transporter.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding Sites; Cell Line; Cocaine; Conserved Sequence; Desipramine; Enzyme Inhibitors; Fluoxetine; Glycine; Humans; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Sequence Alignment; Symporters; Vasoconstrictor Agents | 2002 |
Chronic cocaine self-administration upregulates the norepinephrine transporter and alters functional activity in the bed nucleus of the stria terminalis of the rhesus monkey.
Topics: Animals; Autoradiography; Cocaine; Deoxyglucose; Fluoxetine; Macaca mulatta; Male; Norepinephrine Plasma Membrane Transport Proteins; Self Administration; Septal Nuclei; Symporters; Time Factors; Up-Regulation | 2003 |
Developmental regulation of nicotinic acetylcholine receptor-mediated [3H]norepinephrine release from rat cerebellum.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Cerebellum; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Symporters; Tritium | 2003 |
Age-related changes in the release and uptake activity of presynaptic axon terminals of rat locus coeruleus neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Aging; Animals; Clonidine; Fluoxetine; Frontal Lobe; Infusion Pumps; Locus Coeruleus; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Inbred F344 | 2003 |
Functional coupling of serotonin and noradrenaline transporters.
Topics: Amino Acid Sequence; Animals; Antidepressive Agents; Binding, Competitive; Carrier Proteins; Cell Line; Cell Membrane; Citalopram; Fluoxetine; Humans; Imipramine; Immunoblotting; Kidney; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Recombinant Fusion Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters; Transfection; Tritium | 2003 |
Actions of amphetamine derivatives and cathinone at the noradrenaline transporter.
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Alkaloids; Amphetamines; Animals; Cerebral Cortex; Cocaine; Competitive Bidding; Fluoxetine; In Vitro Techniques; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Wistar; Symporters | 2003 |
Effects of monoamines formed in the cecum of horses on equine digital blood vessels and platelets.
Topics: Adrenergic alpha-Agonists; Animals; Biogenic Amines; Blood Platelets; Cecum; Cystamine; Femoral Artery; Femoral Vein; Fluoxetine; Horses; In Vitro Techniques; Isometric Contraction; Ketanserin; Male; Muscle, Smooth, Vascular; Platelet Activation; Serotonin Antagonists; Vasoconstriction | 2003 |
A new norepinephrine transporter imaging agent for cardiac sympathetic nervous function imaging: radioiodinated (R)-N-methyl-3-(2-iodophenoxy)-3-phenylpropanamine.
Topics: Animals; Cells, Cultured; Desipramine; Fluoxetine; Heart; Heart Ventricles; Humans; Iodine Radioisotopes; Isotope Labeling; Male; Metabolic Clearance Rate; Myocardium; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Symporters; Tissue Distribution | 2003 |
Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines.
Topics: Adrenergic Uptake Inhibitors; Amines; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P450 Family 2; Desipramine; Diffusion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoxetine; Heme; Hydroxylation; Inhibitory Concentration 50; Kinetics; Liver; Male; Microsomes, Liver; Models, Chemical; NADP; Nortriptyline; Oxygen; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Steroid 16-alpha-Hydroxylase; Steroids; Time Factors | 2003 |
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amygdala; Animals; Antidepressive Agents, Tricyclic; Binding, Competitive; Desipramine; Electrochemistry; Excitatory Amino Acid Antagonists; Fluoxetine; Humans; Imipramine; In Vitro Techniques; Locus Coeruleus; Male; Microelectrodes; Norepinephrine Plasma Membrane Transport Proteins; Pyridines; Radioligand Assay; Rats; Receptors, Kainic Acid; Symporters; Time Factors | 2003 |
Role of proline residues in the expression and function of the human noradrenaline transporter.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Cell Line; COS Cells; Fluoxetine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Proline; Protein Structure, Tertiary; Radioligand Assay; Sequence Homology, Amino Acid; Structure-Activity Relationship; Symporters; Transfection; Tritium | 2004 |
Regulation of the norepinephrine transporter by chronic administration of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Autoradiography; Brain; Cerebral Cortex; Desipramine; Fluoxetine; Hippocampus; In Situ Hybridization; Locus Coeruleus; Male; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Symporters | 2004 |
Effect of the wake-promoting agent modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study.
Topics: Animals; Benzhydryl Compounds; Carbachol; Cholinergic Agonists; Clonidine; Electrophysiology; Fluoxetine; Histamine; In Vitro Techniques; Modafinil; Neurons; Neuroprotective Agents; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Sleep; Sympathomimetics; Visual Pathways; Wakefulness | 2004 |
The persistent membrane retention of desipramine causes lasting inhibition of norepinephrine transporter function.
Topics: Adrenergic Uptake Inhibitors; Cell Line; Cell Membrane; Desipramine; Fluoxetine; Humans; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Time Factors | 2004 |
Characterization of dopamine transport in crude synaptosomes prepared from rat medial prefrontal cortex.
Topics: Animals; Biological Transport; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Synaptosomes; Time Factors; Tritium | 2004 |
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS.
Topics: Adrenergic Uptake Inhibitors; Animals; Blotting, Northern; Central Nervous System; Cocaine; Dopamine Uptake Inhibitors; Enkephalins; Fluoxetine; Gene Expression; Male; Piperazines; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Selective Serotonin Reuptake Inhibitors | 2004 |
Uptake and release of norepinephrine by serotonergic terminals in norepinephrine transporter knock-out mice: implications for the action of selective serotonin reuptake inhibitors.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Berberine; Electric Stimulation; Female; Fluoxetine; Frontal Lobe; Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Receptors, Adrenergic, alpha-2; Serotonin Plasma Membrane Transport Proteins; Symporters | 2004 |
Functional importance of the C-terminus of the human norepinephrine transporter.
Topics: Alternative Splicing; Amino Acid Substitution; Binding, Competitive; Cells, Cultured; Exons; Fluoxetine; Humans; Kidney; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Symporters; Transfection; Tritium | 2004 |
Dopamine uptake inhibitor-induced rotation in 6-hydroxydopamine-lesioned rats involves both D1 and D2 receptors but is modulated through 5-hydroxytryptamine and noradrenaline receptors.
Topics: Animals; Chlorobenzenes; Cyclobutanes; Dopamine Uptake Inhibitors; Fluoxetine; Male; Motor Activity; Norepinephrine; Oxidopamine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Rotation | 2005 |
Development of the norepinephrine transporter in the rat CNS.
Topics: Animals; Animals, Newborn; Central Nervous System; Female; Fluoxetine; Gene Expression Regulation, Developmental; Male; Norepinephrine Plasma Membrane Transport Proteins; Pregnancy; Rats; Rats, Sprague-Dawley; Symporters; Tritium | 2005 |
Reduced MPTP toxicity in noradrenaline transporter knockout mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Blotting, Western; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Electrochemistry; Fluoxetine; Homovanillic Acid; Immunohistochemistry; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; MPTP Poisoning; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Symporters; Time Factors; Tyrosine 3-Monooxygenase; Vesicular Biogenic Amine Transport Proteins | 2004 |
Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain.
Topics: Animals; Autoradiography; Benzylamines; Brain; Brain Chemistry; Carbon Isotopes; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Protein Binding; Rats; Rats, Wistar; Serotonin Plasma Membrane Transport Proteins; Sleep Deprivation; Tritium | 2005 |
Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters.
Topics: Animals; Autoradiography; Brain; Citalopram; Competitive Bidding; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Mice; Mice, Knockout; Norepinephrine Plasma Membrane Transport Proteins; Phenols; Piperazines; Protein Binding; Radiopharmaceuticals; Selective Serotonin Reuptake Inhibitors; Symporters; Tissue Distribution | 2005 |
Effects of chronic cocaine self-administration on norepinephrine transporters in the nonhuman primate brain.
Topics: Animals; Autoradiography; Behavior, Animal; Brain; Brain Mapping; Carbon Isotopes; Cocaine; Deoxyglucose; Dopamine Uptake Inhibitors; Drug Administration Schedule; Fluoxetine; Macaca mulatta; Male; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Self Administration; Tritium | 2005 |
Norepinephrine transporter immunoblotting and radioligand binding in cocaine abusers.
Topics: Antibodies; Antibody Specificity; Binding Sites; Binding, Competitive; Brain Chemistry; Cerebral Cortex; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Fluoxetine; Humans; Immunoblotting; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Symporters; Up-Regulation | 2005 |
Pharmacological profile of radioligand binding to the norepinephrine transporter: instances of poor indication of functional activity.
Topics: Binding Sites; Binding, Competitive; Brain Chemistry; Buffers; Cell Line; Cell Membrane; Cocaine; Dopamine Uptake Inhibitors; Fluoxetine; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Radioligand Assay; Reproducibility of Results; Symporters; Temperature | 2005 |
Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil.
Topics: Adrenergic Agents; Animals; Benzhydryl Compounds; Benzylamines; Brain; Central Nervous System Stimulants; Dopamine; Dopamine Agonists; Fluoxetine; Male; Mice; Modafinil; Narcolepsy; Neural Pathways; Norepinephrine; Quinpirole; Sleep; Wakefulness | 2005 |
Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Age Factors; Aging; Analysis of Variance; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Mapping; Clonidine; Cocaine; Cognition Disorders; Discrimination Learning; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Macaca mulatta; Male; Membrane Proteins; Memory; Nerve Tissue Proteins; Neuropsychological Tests; Prazosin; Prefrontal Cortex; Radioligand Assay; Receptors, Catecholamine; Statistics as Topic; Tritium | 2005 |
Iron deficiency: differential effects on monoamine transporters.
Topics: Animals; Brain; Caudate Nucleus; Dopamine Plasma Membrane Transport Proteins; Female; Fluoxetine; Iron; Iron Deficiencies; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Nucleus Accumbens; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Substantia Nigra; Symporters; Tritium | 2005 |
Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons.
Topics: Animals; Benzopyrans; Carbon Radioisotopes; Fluoxetine; Ligands; Maprotiline; Molecular Structure; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Stereoisomerism; Symporters | 2005 |
Modeling and analysis of PET studies with norepinephrine transporter ligands: the search for a reference region.
Topics: Animals; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Fluoxetine; Ligands; Morpholines; Papio; Positron-Emission Tomography; Raclopride; Reboxetine | 2005 |
Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Benzazepines; Cocaine; Desipramine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Lidocaine; Long-Term Potentiation; Neurotransmitter Uptake Inhibitors; Piperazines; Propranolol; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrodotoxin | 2005 |
Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisox
Topics: Adrenergic Uptake Inhibitors; Animals; Autoradiography; Benzopyrans; Binding, Competitive; Brain; Brain Chemistry; Brain Mapping; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Evaluation Studies as Topic; Fluorine Radioisotopes; Fluoxetine; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Maprotiline; Mice; Morpholines; Nordefrin; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Reboxetine; Symporters; Time Factors; Tissue Distribution | 2005 |
Quinolinic acid toxicity on orexin neurons blocked by gamma aminobutyric acid type A receptor stimulation.
Topics: Animals; Animals, Newborn; Bicuculline; Cell Count; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Magnesium; Neurons; Neuropeptides; Nipecotic Acids; Norepinephrine; Orexin Receptors; Orexins; Organophosphorus Compounds; Picrotoxin; Quinolinic Acid; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Selective Serotonin Reuptake Inhibitors; Serotonin | 2005 |
Alpha-adrenergic modulation of synaptic transmission in rabbit pancreatic ganglia.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Ganglia, Autonomic; Guanethidine; Male; Neural Inhibition; Norepinephrine; Pancreas; Phenylephrine; Rabbits; Receptors, Adrenergic; Synaptic Transmission; Yohimbine | 2005 |
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.
Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine | 2005 |
Galanin-mediated anxiolytic effect in rat central amygdala is not a result of corelease from noradrenergic terminals.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Amygdala; Animals; Anti-Anxiety Agents; Autoradiography; Behavior, Animal; Cell Count; Cholera Toxin; Drug Interactions; Fluoxetine; Galanin; Gene Expression Regulation; Immunohistochemistry; In Situ Hybridization; Locus Coeruleus; Male; Maze Learning; Norepinephrine; Oncogene Proteins v-fos; Oxidopamine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Restraint, Physical; Septal Nuclei; Stilbamidines; Stress, Physiological; Tritium; Yohimbine | 2006 |
Noradrenaline transporter and its turnover rate are decreased in blood lymphocytes of patients with major depression.
Topics: Adult; Blood Platelets; Cell Membrane; Depressive Disorder, Major; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Lymphocytes; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Serotonin | 2005 |
Norepinephrine transporter: a candidate gene for initial ethanol sensitivity in inbred long-sleep and short-sleep mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Central Nervous System Depressants; DNA, Complementary; Ethanol; Female; Fluoxetine; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Norepinephrine Plasma Membrane Transport Proteins; Phenotype; Postural Balance; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sleep | 2005 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Dendrites; Female; Fluoxetine; Hippocampus; Humans; Idazoxan; In Situ Hybridization; Lewy Body Disease; Locus Coeruleus; Male; Middle Aged; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; RNA, Messenger; Tetralones; Tyrosine 3-Monooxygenase | 2006 |
Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice.
Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Inhibition, Psychological; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine Plasma Membrane Transport Proteins; Reaction Time; Reflex, Startle; Selective Serotonin Reuptake Inhibitors | 2006 |
Distribution of norepinephrine transporters in the non-human primate brain.
Topics: Animals; Autoradiography; Brain; Fluoxetine; Macaca mulatta; Male; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Tritium | 2006 |
Iron deficiency affects acoustic startle response and latency, but not prepulse inhibition in young adult rats.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Behavior, Animal; Benzazepines; Brain; Brain Chemistry; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Radiation; Female; Fluoxetine; Inhibition, Psychological; Iron; Iron Deficiencies; Linear Models; Liver; Male; Protein Binding; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex, Acoustic; Reflex, Startle; Sex Factors | 2006 |
(-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.
Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Clorgyline; Dose-Response Relationship, Drug; Fluoxetine; Humans; Imipramine; Iproniazid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Selegiline; Serotonin; Stilbenes; Synaptosomes; Tritium; Wine | 2006 |
Inhibition of dopamine and norepinephrine reuptake produces additive effects on energy balance in lean and obese mice.
Topics: Animals; Behavior, Animal; Body Weight; Bupropion; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Eating; Energy Metabolism; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Motor Activity; Neurotransmitter Uptake Inhibitors; Norepinephrine; Obesity; Piperazines; Time Factors | 2007 |
KCl stimulation increases norepinephrine transporter function in PC12 cells.
Topics: Analysis of Variance; Animals; Biological Transport; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fluoxetine; Norepinephrine; PC12 Cells; Potassium Chloride; Protein Binding; Rats; Time Factors; Tritium | 2006 |
Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters.
Topics: Alanine; Animals; Benztropine; Binding, Competitive; Biological Transport; Bupropion; Chlorocebus aethiops; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Models, Molecular; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Serine; Transfection; Tritium | 2006 |
Blockade of noradrenaline transport abolishes 4-methylthioamphetamine-induced contraction of the rat aorta in vitro.
Topics: Adrenergic Uptake Inhibitors; Amphetamines; Animals; Aorta, Thoracic; Biological Transport; Brain; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Wistar; Synaptosomes; Tritium; Vasoconstriction | 2006 |
Role of noradrenergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Female; Fluoxetine; Norepinephrine; Phentolamine; Prazosin; Pressure; Rats; Rats, Sprague-Dawley; Sneezing; Urethra; Urinary Incontinence, Stress; Vagina | 2007 |
Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antidepressive Agents; Chlorocebus aethiops; Cocaine; COS Cells; Cysteine; Fluoxetine; Humans; Molecular Sequence Data; Mutation; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Structure, Tertiary; Radioligand Assay | 2007 |
In vivo assessment of [11C]MRB as a prospective PET ligand for imaging the norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Animals; Carbon Radioisotopes; Diagnostic Imaging; Fluoxetine; Image Processing, Computer-Assisted; Kinetics; Ligands; Morpholines; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Reboxetine; Sensitivity and Specificity; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2007 |
chi-Conotoxin and tricyclic antidepressant interactions at the norepinephrine transporter define a new transporter model.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Antidepressive Agents, Tricyclic; Biological Transport; Conotoxins; Crystallography, X-Ray; Dopamine; Fluoxetine; Glutamic Acid; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurotoxins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Isoforms; Protein Structure, Tertiary; Sequence Alignment | 2007 |
Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate.
Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; In Vitro Techniques; Male; Methylphenidate; Quinolizines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship | 2007 |
Noradrenergic mechanisms in cocaine-induced reinstatement of drug seeking in squirrel monkeys.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Addictive; Behavior, Animal; Clonidine; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Interactions; Extinction, Psychological; Fluoxetine; Flupenthixol; Grooming; Hydrocortisone; Injections, Intravenous; Norepinephrine; Piperazines; Prazosin; Propranolol; Receptors, Adrenergic, alpha-2; Saimiri; Saliva; Self Administration; Thiophenes | 2007 |
Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters.
Topics: Animals; Body Temperature; Central Nervous System Stimulants; Dopamine Plasma Membrane Transport Proteins; Female; Fever; Fluoxetine; Interleukin-1beta; Lethal Dose 50; Male; Methamphetamine; Mice; Mice, Knockout; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2007 |
Desvenlafaxine succinate identifies novel antagonist binding determinants in the human norepinephrine transporter.
Topics: Binding Sites; Binding, Competitive; Blotting, Western; Cells, Cultured; Cocaine; Cyclohexanols; Desvenlafaxine Succinate; Fluoxetine; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay | 2007 |
Halothane increases non-vesicular [(3)H]dopamine release from brain cortical slices.
Topics: Anesthetics, Inhalation; Animals; Cerebral Cortex; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Fluoxetine; Halothane; Male; Nomifensine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Rats; Rats, Wistar; Tetrodotoxin; Transport Vesicles; Tritium | 2007 |
Catecholamine reuptake inhibition causes weight loss by increasing locomotor activity and thermogenesis.
Topics: Animals; Area Under Curve; Behavior, Animal; Bupropion; Catecholamines; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Eating; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Norepinephrine; Norethandrolone; Piperazines; Telemetry; Thermogenesis; Time Factors; Weight Loss | 2008 |
Molecular cloning and functional expression of the murine noradrenaline transporter.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Female; Fluoxetine; Humans; Kinetics; Mice; Mice, Inbred C57BL; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Placenta; Protein Isoforms; Radioligand Assay; Transfection | 2007 |
Sex mediates dopamine and adrenergic receptor expression in adult rats exposed prenatally to cocaine.
Topics: Adrenergic alpha-Agonists; Animals; Autoradiography; Behavior, Animal; Benzazepines; Brain Chemistry; Clonidine; Cocaine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluoxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Sex Characteristics; Tetrahydronaphthalenes | 2007 |
(R)-N-Methyl-3-(3-(125)I-pyridin-2-yloxy)-3-phenylpropan-1-amine: a novel probe for norepinephrine transporters.
Topics: Animals; Autoradiography; Brain; Cell Line; Fluoxetine; Iodine Radioisotopes; LLC-PK1 Cells; Male; Norepinephrine Plasma Membrane Transport Proteins; Propylamines; Pyridines; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2008 |
Evaluation of radioiodinated (2S,alphaS)-2-(alpha-(2-iodophenoxy)benzyl)morpholine as a radioligand for imaging of norepinephrine transporter in the heart.
Topics: Animals; Binding, Competitive; Desipramine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Heart; Iodine Radioisotopes; Isotope Labeling; Metabolic Clearance Rate; Morpholines; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Rats; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution | 2008 |
Monoaminergic compensation in the neuropeptide Y deficient mouse brain.
Topics: Animals; Autoradiography; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Citalopram; Fluoxetine; Immunohistochemistry; Male; Mice; Mice, Knockout; Neuropeptide Y; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tyrosine 3-Monooxygenase | 2008 |
N-Ethylmaleimide differentially inhibits substrate uptake by and ligand binding to the noradrenaline transporter.
Topics: Adenosine Triphosphate; Biological Transport; Cell Line; Dose-Response Relationship, Drug; Ethylmaleimide; Fluoxetine; Humans; Ligands; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Potassium; Protein Binding; Sodium; Sulfhydryl Reagents; Transfection | 2008 |
Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine.
Topics: alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Binding, Competitive; Brain; Depressive Disorder; Desipramine; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Fluoxetine; Male; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stress, Psychological; Synaptic Transmission; Time | 2008 |
Metabolism and autoradiographic evaluation of [(18)F]FE@CIT: a Comparison with [(123)I]beta-CIT and [(123)I]FP-CIT.
Topics: Aniline Compounds; Animals; Autoradiography; Binding, Competitive; Carboxylesterase; Cocaine; Dopamine Plasma Membrane Transport Proteins; Drug Stability; Fluoxetine; Kinetics; Male; Norepinephrine Plasma Membrane Transport Proteins; Nortropanes; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Sulfides; Tropanes | 2008 |
Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Genotype; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Prefrontal Cortex; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Species Specificity; Tyrosine 3-Monooxygenase | 2008 |
Cardiac norepinephrine transporter protein expression is inversely correlated to chamber norepinephrine content.
Topics: Animals; Blotting, Western; Fluoxetine; Heart; Immunohistochemistry; Male; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; Rats; Rats, Sprague-Dawley; Stellate Ganglion; Sympathectomy, Chemical; Sympatholytics; Tritium | 2008 |
Mouse strain differences in immobility and sensitivity to fluvoxamine and desipramine in the forced swimming test: analysis of serotonin and noradrenaline transporter binding.
Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depression; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Serotonin Plasma Membrane Transport Proteins; Species Specificity; Swimming | 2008 |
In vitro binding assays using (3)H nisoxetine and (3)H WIN 35,428 reveal selective effects of gonadectomy and hormone replacement in adult male rats on norepinephrine but not dopamine transporter sites in the cerebral cortex.
Topics: Animals; Cerebral Cortex; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Estradiol; Fluoxetine; Gonadal Hormones; Male; Norepinephrine Plasma Membrane Transport Proteins; Orchiectomy; Protein Binding; Rats; Rats, Sprague-Dawley; Testosterone Propionate; Time Factors; Tritium | 2009 |
5-HT(1A) activation counteracts cardiovascular but not hypophagic effects of sibutramine in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Appetite Depressants; Blood Pressure; Cyclobutanes; Dose-Response Relationship, Drug; Eating; Fluoxetine; Heart Rate; Male; Models, Animal; Morpholines; Norepinephrine; Pyrimidines; Rats; Rats, Sprague-Dawley; Reboxetine; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Triazines | 2009 |
Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Male; Mice; Norepinephrine; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Taste | 2009 |
Detection of endogenous dopamine changes in Drosophila melanogaster using fast-scan cyclic voltammetry.
Topics: Animals; Animals, Genetically Modified; Central Nervous System; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drosophila melanogaster; Fluoxetine; Hydrazines; Microelectrodes; Reserpine | 2009 |
Stimulatory effects of the soy phytoestrogen genistein on noradrenaline transporter and serotonin transporter activity.
Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Estradiol; Fluoxetine; Fulvestrant; Genistein; Glycine max; Humans; Neuroblastoma; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Phytoestrogens; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Estrogen; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection; Tritium; Vanadates | 2010 |
Endothelin-1 and -3 modulate the neuronal norepinephrine transporter through multiple signalling pathways in the rat posterior hypothalamus.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Endothelin-3; Enzyme Activation; Fluoxetine; Hypothalamus, Posterior; Male; Neurons; Nitric Oxide; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Oligopeptides; Piperidines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction | 2010 |
Amphetamine modulation of long-term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant.
Topics: Amphetamine; Animals; Dopamine D2 Receptor Antagonists; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Fluoxetine; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Norepinephrine; Prefrontal Cortex; Receptors, Adrenergic, beta; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2010 |
Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Binding Sites; Cell Count; Dopamine beta-Hydroxylase; Female; Fluoxetine; Humans; Locus Coeruleus; Male; Middle Aged; Neurons; Norepinephrine Plasma Membrane Transport Proteins; Parkinson Disease; Protein Binding; RNA, Messenger; Tritium; Tyrosine 3-Monooxygenase | 2011 |
Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.
Topics: Amphetamine; Benztropine; Binding Sites; Biotinylation; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Fluoxetine; HEK293 Cells; Humans; Immunoblotting; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Pharmacokinetics; Protein Conformation | 2011 |
Characterization of [³H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive.
Topics: Binding, Competitive; Cocaine; Fluoxetine; HEK293 Cells; Humans; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Radiopharmaceuticals; Tritium | 2012 |
Nisoxetine produces local but not systemic analgesia against cutaneous nociceptive stimuli in the rat.
Topics: Anesthetics, Local; Animals; Diffusion; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluoxetine; Injections, Subcutaneous; Kinetics; Male; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Skin | 2012 |
The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cats; Cell Respiration; DNA, Mitochondrial; Electron Transport; Ethanolamines; Female; Fluoxetine; Formoterol Fumarate; Heart; Isoproterenol; Kidney; Male; Mice; Mice, Inbred C57BL; Mitochondria; Organelle Biogenesis; Oxygen Consumption; PPAR gamma; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Signal Transduction | 2012 |
Ex vivo and in vivo evaluation of the norepinephrine transporter ligand [11C]MRB for brown adipose tissue imaging.
Topics: Adipose Tissue, Brown; Animals; Fluoxetine; Ligands; Male; Morpholines; Norepinephrine Plasma Membrane Transport Proteins; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Reboxetine; Wakefulness | 2012 |
Cortico-subcortical neuromodulation involved in the amelioration of prepulse inhibition deficits in dopamine transporter knockout mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Brain; Dopamine Plasma Membrane Transport Proteins; Drug Administration Routes; Fluoxetine; Gene Expression Regulation; Glutamate Decarboxylase; Glutaminase; Inhibition, Psychological; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Proto-Oncogene Proteins c-fos; Reflex, Startle; Sex Factors; Stilbamidines | 2012 |
A second extracellular site is required for norepinephrine transport by the human norepinephrine transporter.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding Sites; Biological Transport; Chlorocebus aethiops; Computer Simulation; COS Cells; Fluoxetine; Humans; Leucine; Molecular Docking Simulation; Mutagenesis, Site-Directed; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins | 2012 |
Isobolographic analysis of interaction between nisoxetine- and mepivacaine-induced spinal blockades in rats.
Topics: Analgesics; Anesthesia, Spinal; Anesthetics, Local; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Injections, Spinal; Male; Mepivacaine; Rats; Rats, Sprague-Dawley | 2014 |
The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes.
Topics: Astrocytes; Cell Line, Tumor; Citalopram; Fluoxetine; Glioma; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Paroxetine; Pyridines; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tumor Necrosis Factor-alpha | 2013 |
Pentazocine inhibits norepinephrine transporter function by reducing its surface expression in bovine adrenal medullary cells.
Topics: Adrenal Medulla; Analgesics, Opioid; Animals; Cattle; Cell Line; Cell Membrane; Cells, Cultured; Ethylenediamines; Fluoxetine; Gene Expression; Humans; Naltrexone; Narcotic Antagonists; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pentazocine; Radionuclide Imaging | 2013 |
Impaired cliff avoidance reaction in dopamine transporter knockout mice.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Impulsive Behavior; Male; Methylphenidate; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine Plasma Membrane Transport Proteins; Reflex, Startle; Sensory Gating | 2013 |
High-fat diet-induced alterations in the feeding suppression of low-dose nisoxetine, a selective norepinephrine reuptake inhibitor.
Topics: Animals; Appetite Regulation; Arcuate Nucleus of Hypothalamus; Blood Pressure; Diet, High-Fat; Dose-Response Relationship, Drug; Eating; Fluoxetine; Heart Rate; Immunohistochemistry; Male; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Weight Gain | 2013 |
α2-Adrenergic agonists including xylazine and dexmedetomidine inhibit norepinephrine transporter function in SK-N-SH cells.
Topics: 3-Iodobenzylguanidine; Adrenergic alpha-2 Receptor Agonists; Cell Line, Tumor; Dexmedetomidine; Fluoxetine; Humans; Iodine Radioisotopes; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Receptors, Adrenergic, alpha-2; Xylazine | 2013 |
The role of cysteines and histidins of the norepinephrine transporter.
Topics: Cysteine; Ethylmaleimide; Fluoxetine; HEK293 Cells; Histidine; Humans; Mutagenesis, Site-Directed; Norepinephrine Plasma Membrane Transport Proteins; Radioligand Assay; Subcellular Fractions | 2013 |
Nisoxetine blocks sodium currents and elicits spinal anesthesia in rats.
Topics: Anesthesia, Spinal; Anesthetics, Local; Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluoxetine; Inhibitory Concentration 50; Injections, Spinal; Male; Mepivacaine; Mice; Neuroblastoma; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2013 |
Extracellular loop 3 of the noradrenaline transporter contributes to substrate and inhibitor selectivity.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Chlorocebus aethiops; COS Cells; Extracellular Fluid; Fluoxetine; Humans; Molecular Sequence Data; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Substrate Specificity | 2014 |
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional Chinese medicine, has antidepressant-like activity.
Topics: Animals; Antidepressive Agents; Citalopram; Cocaine; Depression; Disease Models, Animal; Female; Fluoxetine; Male; Medicine, Chinese Traditional; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Motor Activity; Protein Binding; Rats; Rats, Sprague-Dawley; Saponins; Swimming; Tritium | 2014 |
Roles of the spinal glutamatergic pathway activated through α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors and its interactions with spinal noradrenergic and serotonergic pathways in the rat urethral continence mechanisms.
Topics: Animals; Excitatory Amino Acid Antagonists; Female; Fluoxetine; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, AMPA; Reflex; Serotonin Receptor Agonists; Sneezing; Urethra; Urinary Incontinence, Stress | 2015 |
Binge-like eating attenuates nisoxetine feeding suppression, stress activation, and brain norepinephrine activity.
Topics: Animals; Body Weight; Brain; Bulimia; Energy Intake; Feeding Behavior; Fluoxetine; Male; Norepinephrine; Rats; Rats, Sprague-Dawley | 2014 |
Endogenous serotonin facilitates hippocampal long-term potentiation at CA3/CA1 synapses.
Topics: Analysis of Variance; Animals; Biophysics; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation; Fluoxetine; In Vitro Techniques; Long-Term Potentiation; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Net; Pyramidal Cells; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Synapses | 2015 |
Effects of various pharmacological agents on the function of norepinephrine transporter.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenergic Neurons; Animals; Cells, Cultured; Fluoxetine; Genistein; Humans; Ketamine; Nerve Endings; Nicotine; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Pentazocine; Sympathetic Nervous System; Synaptic Transmission | 2015 |
X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine.
Topics: Animals; Antidepressive Agents; Crystallography, X-Ray; Dopamine Plasma Membrane Transport Proteins; Drosophila melanogaster; Drosophila Proteins; Fluoxetine; Morpholines; Protein Binding; Reboxetine | 2015 |
Effects of abstinence from chronic cocaine self-administration on nonhuman primate dorsal and ventral noradrenergic bundle terminal field structures.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Autoradiography; Brain; Cocaine; Cocaine-Related Disorders; Fluoxetine; Idazoxan; Macaca mulatta; Male; Neural Pathways; Norepinephrine Plasma Membrane Transport Proteins; Receptors, Adrenergic, alpha-2; Reinforcement Schedule; Self Administration | 2016 |
Comparison of dopamine kinetics in the larval Drosophila ventral nerve cord and protocerebrum with improved optogenetic stimulation.
Topics: Animals; Central Nervous System; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Drosophila; Electrochemical Techniques; Female; Fluoxetine; Kinetics; Larva; Microelectrodes; Models, Biological; Optogenetics; Rhodopsin; Tyrosine 3-Monooxygenase | 2015 |
Noradrenergic Mechanisms Controlling Urethral Smooth and Striated Muscle Function in Urethral Continence Reflex in Rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic Neurons; Animals; Benzamidines; Bungarotoxins; Female; Fluoxetine; Medetomidine; Muscle, Smooth; Muscle, Striated; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Reflex; Urethra | 2015 |
Acute blockade of the Caenorhabditis elegans dopamine transporter DAT-1 by the mammalian norepinephrine transporter inhibitor nisoxetine reveals the influence of genetic modifications of dopamine signaling in vivo.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluoxetine; Gene Deletion; Mutation; Norepinephrine Plasma Membrane Transport Proteins; Paralysis; Plasmids; Signal Transduction; Swimming | 2016 |
Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apoptosis; Autoreceptors; Blotting, Western; Brain; CASP8 and FADD-Like Apoptosis Regulating Protein; Cerebral Cortex; Clorgyline; Desipramine; Electroshock; Excitatory Amino Acid Antagonists; Fas-Associated Death Domain Protein; Fluoxetine; Idazoxan; Indans; Ketamine; Male; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Norepinephrine Plasma Membrane Transport Proteins; Phenelzine; Phosphoproteins; Phosphorylation; Rats; RNA-Binding Proteins; Thiazoles | 2016 |
Fast-Scan Cyclic Voltammetry (FSCV) Detection of Endogenous Octopamine in Drosophila melanogaster Ventral Nerve Cord.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Adrenergic Uptake Inhibitors; Animals; Animals, Genetically Modified; Central Nervous System; Disulfiram; Dopamine Plasma Membrane Transport Proteins; Drosophila melanogaster; Drosophila Proteins; Electrochemical Techniques; Fluoxetine; Gene Expression Regulation; Light; Neurons; Octopamine; Receptors, Purinergic P2X2; Reserpine; Rhodopsin; Transcription Factors; Tyrosine Decarboxylase | 2016 |
Effect of rat spinal cord injury (hemisection) on the ex vivo uptake and release of [
Topics: Adrenergic Uptake Inhibitors; Animals; Female; Fluoxetine; Neurons; Norepinephrine; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries | 2017 |
Blockade and reversal of swimming-induced paralysis in C. elegans by the antipsychotic and D2-type dopamine receptor antagonist azaperone.
Topics: Animals; Animals, Genetically Modified; Antipsychotic Agents; Azaperone; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Reserpine; Signal Transduction | 2019 |
Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bupropion; Citalopram; Conditioning, Operant; Dopamine Uptake Inhibitors; Fluoxetine; Ketoprofen; Lactic Acid; Male; Mice; Mice, Inbred ICR; Milnacipran; Nesting Behavior; Pain; Receptors, Opioid, kappa; Self Stimulation | 2019 |
Dopamine and norepinephrine transporter inhibition for long-term fear memory enhancement.
Topics: Animals; Atomoxetine Hydrochloride; Behavior, Animal; Bupropion; Central Nervous System Stimulants; Conditioning, Classical; Dopamine Plasma Membrane Transport Proteins; Drug Therapy, Combination; Fear; Female; Fluoxetine; Male; Memory, Long-Term; Mice; Mice, Inbred C57BL; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Norepinephrine Plasma Membrane Transport Proteins | 2020 |
TAS-303 Ameliorates Carbachol-Induced Detrusor Overactivity in Rats, Revealing Its Therapeutic Potential for Overactive Bladder.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Overactive | 2020 |
Inhibition of the norepinephrine transporter rescues vascular hyporeactivity to catecholamine in obstructive jaundice.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Bile Ducts; Bilirubin; Blood Pressure; Blood Vessels; Catecholamines; Fluoxetine; Ganglia, Sympathetic; Jaundice, Obstructive; Ligation; Male; Norepinephrine Plasma Membrane Transport Proteins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2021 |
Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors.
Topics: Biosensing Techniques; Dopamine; Doxycycline; Epinephrine; Fluoxetine; High-Throughput Screening Assays; Humans; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Substrate Specificity | 2021 |
Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function.
Topics: Animals; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Histidine; HIV-1; Humans; Mutation; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Phenylalanine; Rats; Symporters; Trans-Activators; Tyrosine | 2022 |