fluoxetine has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 68 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (5.88) | 18.7374 |
| 1990's | 24 (35.29) | 18.2507 |
| 2000's | 26 (38.24) | 29.6817 |
| 2010's | 13 (19.12) | 24.3611 |
| 2020's | 1 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Arunotayanun, W; Dalley, JW; Gibbons, S; Huang, XP; Iversen, L; Roth, BL; Setola, V; Treble, R | 1 |
| Callaway, CW; Geyer, MA | 1 |
| Azmitia, EC; Berger, UV; Gu, XF | 1 |
| Pan, HS; Wang, RY | 1 |
| Dragunow, M; Laverty, R; Logan, B | 1 |
| Brodkin, J; Nash, JF | 1 |
| Aghajanian, GK; Bradberry, CW; Roth, RH; Sprouse, JS | 2 |
| Azmitia, EC; Murphy, RB; Whitaker-Azmitia, PM | 1 |
| Callaway, CW; Geyer, MA; Wing, LL | 1 |
| Schmidt, CJ; Taylor, VL | 2 |
| Schmidt, CJ | 1 |
| Gudelsky, GA; Meltzer, HY; Nash, JF | 1 |
| Geyer, MA; Krebs, KM | 1 |
| Blyth, AS; Dougall, JR; Kennedy, BW; Nimmo, SM; Tullett, WM | 1 |
| Azmitia, EC; Leonardi, ET | 1 |
| Callaway, CW; Geyer, MA; Rempel, NL | 1 |
| Azmitia, EC; Gu, XF | 1 |
| McCann, UD; Ricaurte, GA | 1 |
| Gudelsky, GA; Nash, JF | 1 |
| Malberg, JE; Sabol, KE; Seiden, LS | 1 |
| Imel, KM; Obradovic, T; White, SR | 1 |
| Schechter, MD | 1 |
| Galloway, MP; Koch, S | 1 |
| Azmitia, EC; Kramer, HK; Poblete, JC | 1 |
| Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O | 1 |
| Gudelsky, GA; Shankaran, M; Yamamoto, BK | 1 |
| Kalia, M; Kramer, M; Miller, DB; O'Callaghan, JP | 1 |
| Baker, LE; Virden, TB | 1 |
| Camarero, J; Colado, MI; Esteban, B; Green, AR; O'Shea, E | 1 |
| Camarero, J; Colado, MI; Esteban, B; Green, AR; Peter, MJ; Sanchez, V | 1 |
| Fantegrossi, WE; Godlewski, T; Karabenick, RL; Rice, KC; Stephens, JM; Ullrich, T; Woods, JH | 1 |
| Cleary, L; Docherty, JR | 1 |
| Clemens, KJ; Cornish, JL; Gurtman, CG; Hunt, GE; Li, KM; McGregor, IS; Thompson, MR | 1 |
| Quick, MW | 1 |
| Camarero, J; Colado, MI; Escobedo, I; Green, AR; Moro, MA; O'Shea, E; Orio, L; Pradillo, JM; Sanchez, V | 1 |
| Brown, AW; Hrometz, SL; Nichols, DE; Sprague, JE | 1 |
| Barnes, NM; Blakely, RD; Bunce, CM; Challa, A; Chamba, A; Drake-Lee, A; Drayson, MT; Dyer, MJ; Gordon, J; Holder, MJ; Meredith, EJ; Pilkington, G | 1 |
| Adkins, EM; Blakely, RD; Field, JR; Henry, LK; Newman, AH; Parnas, ML; Vaughan, RA; Zou, MF | 1 |
| Aguirre, N; Goñi-Allo, B; Herv'as, I; Lasheras, B; Ramos, M | 1 |
| Baumann, MH; Rothman, RB; Zolkowska, D | 1 |
| Guiry, PJ; Keenan, AK; McBean, GJ; Quinn, ST; Schwab, T | 1 |
| Johanson, CE; Tancer, M | 1 |
| Colado, MI; Escobedo, I; O'Shea, E; Orio, L; Peraile, I | 1 |
| Cuppen, E; Homberg, JR; Schiepers, OJ; Schoffelmeer, AN; Vanderschuren, LJ | 1 |
| Eddington, ND; Upreti, VV | 1 |
| Greenwald, MK | 1 |
| Bastos, ML; Capela, JP; Carvalho, F; Dirnagl, U; Lautenschlager, M; Meisel, A | 1 |
| Ashford, KA; Christie, IN; Evans, AK; Lowry, CA; Reinders, N; Wakerley, JB | 1 |
| Durkin, S; Harkin, A; Prendergast, A | 1 |
| Hasegawa, R; Ikeda, K; Karasawa, J; Tamura, K; Yamamoto, H; Yamamoto, T; Yasumoto, S | 1 |
| Cardenas, FP; Landeira-Fernandez, J; León, LA | 1 |
| Chyueh, SC; Hu, SH; Huang, WS; Huang, YY; Li, IH; Liao, MH; Liu, JC; Liu, RS; Ma, KH; Shen, LH; Shiue, CY | 1 |
| Adori, C; Andó, RD; Bagdy, G; Ferrington, L; Kelly, PA; Kirilly, E; Kovács, GG; Molnár, E | 1 |
| Ayala, ME | 1 |
| Drummer, OH; Gerostamoulos, D; Pilgrim, JL | 1 |
| Bhide, N; Gudelsky, GA; Pachmerhiwala, R; Straiko, M | 1 |
| Iwamura, T; Kasai, M; Kato, S; Nisijima, K; Shioda, K; Yoshino, T | 1 |
| Chen, CY; Chen, YA; Cheng, CY; Huang, SY; Huang, WS; Li, IH; Lin, YS; Liu, RS; Ma, KH; Shiue, CY; Wang, SJ | 1 |
| Howell, LL; Kimmel, HL; Murnane, KS; Rice, KC | 1 |
| Anneken, JH; Gudelsky, GA | 1 |
| Aguilar, MA; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M; Roger-Sánchez, C | 1 |
| Corradetti, R; Mlinar, B; Stocca, G | 1 |
| Antunes, MJ; Carvalho, F; Cotrim, MD; Fernandes, E; Silva, S | 1 |
| Forsblad, A; Hashemian, S; Jacobsson, SO; Popova, D | 1 |
| Bowman, SK; Huang, S; Rice, KC; Riley, AL; Vasquez, ME | 1 |
1 review(s) available for fluoxetine and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
1 trial(s) available for fluoxetine and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
The effects of fluoxetine on the subjective and physiological effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans.
Topics: Adult; Affect; Behavior; Blood Pressure; Cardiovascular Physiological Phenomena; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Fluoxetine; Hallucinogens; Heart Rate; Humans; Male; Mental Processes; N-Methyl-3,4-methylenedioxyamphetamine; Selective Serotonin Reuptake Inhibitors; Serotonin Agents | 2007 |
66 other study(ies) available for fluoxetine and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.
Topics: Allyl Compounds; HEK293 Cells; Humans; Indoles; Magnetic Resonance Spectroscopy; Molecular Conformation; Propylamines; Protein Binding; Psychotropic Drugs; Receptors, Serotonin; Serotonin Receptor Agonists; Spectrophotometry, Ultraviolet; Tryptamines | 2013 |
Stimulant effects of 3,4-methylenedioxymethamphetamine in the nucleus accumbens of rat.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Behavior, Animal; Corpus Striatum; Fluoxetine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Inbred Strains | 1992 |
The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cocaine; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; p-Chloroamphetamine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes | 1992 |
MDMA: further evidence that its action in the medial prefrontal cortex is mediated by the serotonergic system.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Cerebral Cortex; Electrophysiology; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Stereoisomerism; Stereotaxic Techniques | 1991 |
3,4-Methylenedioxymethamphetamine induces Fos-like proteins in rat basal ganglia: reversal with MK 801.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Basal Ganglia; Caudate Nucleus; Corpus Striatum; Dizocilpine Maleate; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Olfactory Bulb; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Putamen; Rats | 1991 |
Microdialysis studies on 3,4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; Fluoxetine; Ketanserin; Male; Mazindol; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Fluoxetine; Microchemistry; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Secretory Rate; Serotonin; Tryptophan | 1991 |
MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2(+)-dependent toxicity linked to release.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Calcium; Cells, Cultured; Embryo, Mammalian; Fluoxetine; Ketanserin; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Serotonin | 1990 |
Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamine; Amphetamines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; Fluoxetine; Gait; Injections, Subcutaneous; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Reversal of the acute effects of 3,4-methylenedioxymethamphetamine by 5-HT uptake inhibitors.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Fluoxetine; Indenes; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase | 1990 |
Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain; Cerebral Cortex; Fluoxetine; Hydroxyindoleacetic Acid; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Time Factors | 1987 |
MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Dialysis; Electrophysiology; Fluoxetine; In Vitro Techniques; Male; Mesencephalon; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Passive Cutaneous Anaphylaxis; Raphe Nuclei; Rats; Serotonin; Stereoisomerism; Time Factors | 1989 |
Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Cerebral Cortex; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Ketanserin; Kinetics; Male; Methiothepin; N-Methyl-3,4-methylenedioxyamphetamine; Piperonyl Butoxide; Propylamines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tryptophan Hydroxylase | 1987 |
Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Body Temperature; Corticosterone; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists | 1988 |
Behavioral characterization of alpha-ethyltryptamine, a tryptamine derivative with MDMA-like properties in rats.
Topics: Animals; Behavior, Animal; Exploratory Behavior; Fluoxetine; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Tryptamines | 1993 |
Drug-induced hyperthermia.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Fluoxetine; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Neuroleptic Malignant Syndrome; Remoxipride; Thioridazine | 1993 |
MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac).
Topics: Animals; Binding, Competitive; Brain; Drug Interactions; Fenfluramine; Fluoxetine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Serotonin1B receptor activation mimics behavioral effects of presynaptic serotonin release.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Caffeine; Designer Drugs; Dopamine Agents; Dose-Response Relationship, Drug; Fluoxetine; Indoles; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nicotine; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Receptor Agonists; Synapses | 1993 |
Integrative transporter-mediated release from cytoplasmic and vesicular 5-hydroxytryptamine stores in cultured neurons.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Stem; Carrier Proteins; Cells, Cultured; Clorgyline; Female; Fluoxetine; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurons; Nimodipine; p-Chloroamphetamine; Pregnancy; Rats; Rats, Sprague-Dawley; Reserpine; Selegiline; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1993 |
Reinforcing subjective effects of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") may be separable from its neurotoxic actions: clinical evidence.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Arousal; Designer Drugs; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Female; Fluoxetine; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Reinforcement, Psychology; Substance-Related Disorders | 1993 |
Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carrier Proteins; Corpus Striatum; Dopamine; Drug Synergism; Fluoxetine; Frontal Lobe; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tetrodotoxin | 1996 |
Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat.
Topics: Animals; Body Temperature; Drug Combinations; Fluoxetine; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Tyrosine | 1996 |
Methylenedioxymethamphetamine-induced inhibition of neuronal firing in the nucleus accumbens is mediated by both serotonin and dopamine.
Topics: Animals; Dopamine; Fluoxetine; Male; Membrane Potentials; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin | 1996 |
Serotonergic mediation of fenfluramine discriminative stimuli in fawn-hooded rats.
Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Fluoxetine; Ibogaine; Male; Methoxydimethyltryptamines; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Quipazine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Receptor Agonists | 1997 |
MDMA induced dopamine release in vivo: role of endogenous serotonin.
Topics: Animals; Chromatography, High Pressure Liquid; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; In Vitro Techniques; Ketanserin; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Antagonists | 1997 |
Activation of protein kinase C (PKC) by 3,4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter.
Topics: Animals; Binding Sites; Brain; Brain Stem; Carrier Proteins; Cerebral Cortex; Enzyme Activation; Female; Fluoxetine; Hippocampus; Ketanserin; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins | 1997 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection | 1999 |
Involvement of the serotonin transporter in the formation of hydroxyl radicals induced by 3,4-methylenedioxymethamphetamine.
Topics: Animals; Carrier Proteins; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Fluoxetine; Hydroxybenzoates; Hydroxyl Radical; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Salicylic Acid; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors | 1999 |
Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry.
Topics: Animals; Appetite Depressants; Body Weight; Cyclobutanes; Dexfenfluramine; Eating; Fluoxetine; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Sertraline | 2000 |
Disruption of the discriminative stimulus effects of S(+)-3,4-methylenedioxymethamphetamine (MDMA) by (+/-)-MDMA neurotoxicity: protection by fluoxetine.
Topics: Animals; Brain Chemistry; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Generalization, Stimulus; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nervous System Diseases; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 1999 |
Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Body Temperature; Brain Chemistry; Dopamine; Dopamine Uptake Inhibitors; Fluoxetine; Homovanillic Acid; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2001 |
The mechanisms involved in the long-lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')-induced degeneration of 5-HT nerve endings in rat brain.
Topics: Animals; Binding, Competitive; Body Temperature; Brain; Cerebral Cortex; Fluoxetine; Fluvoxamine; Indoles; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Endings; Neuroprotective Agents; Paroxetine; Rats; Rectum; Serotonin; Serotonin Agents; Time Factors; Tritium | 2001 |
Pharmacological characterization of the effects of 3,4-methylenedioxymethamphetamine ("ecstasy") and its enantiomers on lethality, core temperature, and locomotor activity in singly housed and crowded mice.
Topics: Animals; Body Temperature; Cold Temperature; Crowding; Dose-Response Relationship, Drug; Fluorobenzenes; Fluoxetine; Hallucinogens; Ketanserin; Lethal Dose 50; Male; Mice; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Platelet Aggregation Inhibitors; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Social Isolation; Stereoisomerism; Telemetry | 2003 |
Actions of amphetamine derivatives and cathinone at the noradrenaline transporter.
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Alkaloids; Amphetamines; Animals; Cerebral Cortex; Cocaine; Competitive Bidding; Fluoxetine; In Vitro Techniques; Male; Myocardium; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Rats, Wistar; Symporters | 2003 |
Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Body Fluids; Body Temperature; Body Weight; Brain; Carrier Proteins; Chromatography, High Pressure Liquid; Depression; Drinking; Drug Interactions; Fluoxetine; Immobilization; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurotransmitter Agents; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Serotonin Plasma Membrane Transport Proteins; Swimming | 2004 |
Regulating the conducting states of a mammalian serotonin transporter.
Topics: Animals; Antigens, Surface; Binding Sites; Botulinum Toxins, Type A; Carrier Proteins; Cells, Cultured; Choline; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Embryo, Mammalian; Embryo, Nonmammalian; Fluoxetine; Humans; Immunoblotting; Isotope Labeling; Kidney; Membrane Glycoproteins; Membrane Potentials; Membrane Transport Proteins; Microinjections; Molecular Biology; Munc18 Proteins; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neurons; Oocytes; Patch-Clamp Techniques; Peptide Fragments; Proteins; Radiopharmaceuticals; Rats; Recombinant Fusion Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Sodium; Syntaxin 1; Thalamus; Time Factors; Tritium; Vesicular Transport Proteins; Xenopus laevis | 2003 |
3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion.
Topics: Acute Disease; Animals; Astrocytes; Binding, Competitive; Body Temperature; Brain; Cerebral Cortex; Fever; Fluoxetine; Glial Fibrillary Acidic Protein; Hypothalamus; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Isoquinolines; Male; Microglia; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Sialoglycoproteins; Temperature | 2004 |
3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake transporter, and monoamine oxidase-B.
Topics: Cell Line, Tumor; Cell Survival; Choriocarcinoma; Dopamine; Drug Interactions; Female; Fluoxetine; Hallucinogens; Humans; Hydrogen Peroxide; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Pregnancy; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2004 |
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Burkitt Lymphoma; Cell Line, Tumor; Clomipramine; Fenfluramine; Fluoxetine; Humans; Lymphoma, B-Cell; N-Methyl-3,4-methylenedioxyamphetamine; Proto-Oncogene Proteins c-bcl-2; Psychotropic Drugs; Serotonin Plasma Membrane Transport Proteins | 2005 |
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Topics: Adrenergic Uptake Inhibitors; Amino Acid Sequence; Animals; Antidepressive Agents; Binding Sites; Binding, Competitive; Blotting, Western; Cadmium; Cell Line; Cell Membrane; Citalopram; Clomipramine; Cocaine; Cysteine; Dopamine Uptake Inhibitors; Fluoxetine; HeLa Cells; Humans; Immunoprecipitation; Isoleucine; Kinetics; LLC-PK1 Cells; Mazindol; Methionine; Mice; Models, Chemical; Molecular Sequence Data; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Nomifensine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Radiopharmaceuticals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Stereoisomerism; Substrate Specificity; Tyrosine | 2006 |
Studies on striatal neurotoxicity caused by the 3,4-methylenedioxymethamphetamine/ malonate combination: implications for serotonin/dopamine interactions.
Topics: Amphetamine-Related Disorders; Animals; Body Temperature Regulation; Cell Survival; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Hallucinogens; Male; Malonates; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Piperazines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents | 2006 |
Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease.
Topics: Amphetamines; Animals; Central Nervous System Stimulants; Dextroamphetamine; Dose-Response Relationship, Drug; Electrochemistry; Fluoxetine; Heart Diseases; Hydroxyindoleacetic Acid; Indicators and Reagents; Lung Diseases; Male; Methamphetamine; Microdialysis; Mitogens; Muscle, Smooth, Vascular; N-Methyl-3,4-methylenedioxyamphetamine; Phentermine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stimulation, Chemical | 2006 |
Blockade of noradrenaline transport abolishes 4-methylthioamphetamine-induced contraction of the rat aorta in vitro.
Topics: Adrenergic Uptake Inhibitors; Amphetamines; Animals; Aorta, Thoracic; Biological Transport; Brain; Dose-Response Relationship, Drug; Fluoxetine; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Rats; Rats, Wistar; Synaptosomes; Tritium; Vasoconstriction | 2006 |
Evidence for a role of Hsp70 in the neuroprotection induced by heat shock pre-treatment against 3,4-methylenedioxymethamphetamine toxicity in rat brain.
Topics: Animals; Body Temperature; Brain; Brain Chemistry; Epistasis, Genetic; Fluoxetine; Gene Expression Regulation; Hallucinogens; Heating; HSP70 Heat-Shock Proteins; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Rats; Reactive Oxygen Species; Selective Serotonin Reuptake Inhibitors; Serotonin; Time Factors | 2007 |
Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Genetically Modified; Dose-Response Relationship, Drug; Fluoxetine; Male; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Social Behavior | 2007 |
Fluoxetine pretreatment effects pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA, ECSTASY) in rat.
Topics: 3,4-Methylenedioxyamphetamine; Alcohol Oxidoreductases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Caco-2 Cells; Cytochrome P-450 CYP2D6; Cytochrome P450 Family 2; Drug Interactions; Fluoxetine; Humans; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley | 2008 |
Behavioral economic analysis of drug preference using multiple choice procedure data.
Topics: Choice Behavior; Economics; Fentanyl; Fluoxetine; Hallucinogens; Humans; Hydromorphone; Injections, Intramuscular; Methadone; Models, Psychological; Motivation; N-Methyl-3,4-methylenedioxyamphetamine; Naltrexone; Narcotics; Psychotropic Drugs; Recreation; Selective Serotonin Reuptake Inhibitors; Substance Abuse, Intravenous; Substance-Related Disorders | 2008 |
5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures.
Topics: 5,7-Dihydroxytryptamine; Animals; Cells, Cultured; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Fluoxetine; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Degeneration; Nerve Fibers; Raphe Nuclei; Rats | 2008 |
Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex.
Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Fluoxetine; Hydrazines; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Pargyline; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Time Factors; Tryptophan | 2008 |
Reduced efficacy of fluoxetine following MDMA ("Ecstasy")-induced serotonin loss in rats.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebral Cortex; Drug Interactions; Fluoxetine; Hallucinogens; Immobility Response, Tonic; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Swimming; Time Factors; Tritium | 2008 |
Inhibitory effect of selective serotonin reuptake inhibitors on the vesicular monoamine transporter 2.
Topics: Animals; Dopamine; Fluoxetine; Fluvoxamine; Haloperidol; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Wistar; Reserpine; Selective Serotonin Reuptake Inhibitors; Synaptic Vesicles; Vesicular Monoamine Transport Proteins | 2009 |
Effects of chronic intracerebroventricular 3,4-methylenedioxy-N-methamphetamine (MDMA) or fluoxetine on the active avoidance test in rats with or without exposure to mild chronic stress.
Topics: Analysis of Variance; Animals; Avoidance Learning; Chronic Disease; Depression; Disease Models, Animal; Fluoxetine; Injections, Intraventricular; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Rats; Rats, Wistar; Reaction Time; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Stress, Psychological | 2009 |
Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET.
Topics: Animals; Brain; Fluoxetine; Immunohistochemistry; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Photomicrography; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2010 |
Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion.
Topics: Animals; Anxiety; Axons; Brain; Citalopram; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neuropsychological Tests; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Social Behavior; Time Factors | 2010 |
Brain serotonin, psychoactive drugs, and effects on reproduction.
Topics: Affect; Amphetamine-Related Disorders; Animals; Biological Clocks; Brain; Cognition Disorders; Depressive Disorder; Drug Interactions; Female; Fenfluramine; Fluoxetine; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Obesity; Psychotropic Drugs; Reproduction; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Substance-Related Disorders; Synaptic Transmission | 2009 |
Deaths involving serotonergic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Cause of Death; Citalopram; Cyclohexanols; Female; Fluoxetine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Serotonin Agents; Sertraline; Tramadol; Venlafaxine Hydrochloride | 2010 |
Role of serotonin and/or norepinephrine in the MDMA-induced increase in extracellular glucose and glycogenolysis in the rat brain.
Topics: Animals; Brain; Fever; Fluoxetine; Glucose; Glycogenolysis; Male; N-Methyl-3,4-methylenedioxyamphetamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Serotonin | 2010 |
The effects of mirtazapine and fluoxetine on hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) in rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Fever; Fluoxetine; Male; Mianserin; Mirtazapine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents | 2011 |
Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study.
Topics: Animals; Benzylamines; Brain; Female; Fluorine Radioisotopes; Fluoxetine; Macaca; Male; N-Methyl-3,4-methylenedioxyamphetamine; Positron-Emission Tomography; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution | 2012 |
The neuropharmacology of prolactin secretion elicited by 3,4-methylenedioxymethamphetamine ("ecstasy"): a concurrent microdialysis and plasma analysis study.
Topics: Animals; Female; Fluorobenzenes; Fluoxetine; Hallucinogens; Macaca mulatta; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Piperidines; Prolactin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Antagonists; Stereoisomerism; Time Factors | 2012 |
MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus.
Topics: Adrenergic Uptake Inhibitors; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Fluoxetine; Glutamic Acid; Hippocampus; Ketanserin; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Neostriatum; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Neurochemical substrates of MDMA reward: effects of the inhibition of serotonin reuptake on the acquisition and reinstatement of MDMA-induced CPP.
Topics: Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Hallucinogens; Male; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin | 2013 |
Endogenous serotonin facilitates hippocampal long-term potentiation at CA3/CA1 synapses.
Topics: Analysis of Variance; Animals; Biophysics; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Electric Stimulation; Fluoxetine; In Vitro Techniques; Long-Term Potentiation; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Net; Pyramidal Cells; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Synapses | 2015 |
Contractile effects of 3,4-methylenedioxymethamphetamine on the human internal mammary artery.
Topics: Fluoxetine; Hallucinogens; Humans; In Vitro Techniques; Isometric Contraction; Ketanserin; Mammary Arteries; N-Methyl-3,4-methylenedioxyamphetamine; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 2016 |
Non-Serotonergic Neurotoxicity by MDMA (Ecstasy) in Neurons Derived from Mouse P19 Embryonal Carcinoma Cells.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Survival; Clorgyline; Embryonal Carcinoma Stem Cells; Fluoxetine; Gene Expression; Membrane Potential, Mitochondrial; Mice; Monoamine Oxidase; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Selegiline; Serotonin Plasma Membrane Transport Proteins | 2016 |
Impact of fluoxetine preexposure on MDMA-induced taste avoidance in male and female rats.
Topics: Animals; Avoidance Learning; Fluoxetine; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Taste | 2023 |