fluoxetine and morphine

fluoxetine has been researched along with morphine in 52 studies

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-199011 (21.15)18.7374
1990's8 (15.38)18.2507
2000's15 (28.85)29.6817
2010's17 (32.69)24.3611
2020's1 (1.92)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Nagashima, R; Nishikawa, T; Tobita, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Basbaum, AI; Brown, JL; Matos, FF; Rollema, H1
Suh, HH; Tseng, LL1
Kleven, MS; Sparber, SB1
Izenwasser, S; Kornetsky, C2
Goldstein, FJ; Kellstein, DE; Malseed, RT; Ossipov, MH1
Flood, JF; Morley, JE1
Maickel, RP; Spratto, GR; Tocco, DR1
Bemis, KG; Hymson, DL; Hynes, MD; Lochner, MA1
Bero, LA; Kuhn, CM1
Fuller, RW; Krushinski, JH; Leander, JD; Robertson, DW1
Callahan, P; Grandison, L; Rabii, J1
Leander, JD; McCleary, P1
Gear, RW; Gordon, NC; Heller, PH; Levine, JD1
Akunne, HC; Soliman, KF1
Etgen, AM; Sokol, J; Vathy, I1
Backer, MM; Pick, CG; Schreiber, S1
Fletcher, PJ; Sills, TL1
Kornetsky, C; Wennemer, HK1
Coda, BA; Donaldson, G; Erjavec, MK; Nguyen, Q; Risler, L; Shen, DD1
Aston-Jones, G; Harris, GC1
Hassanpour, M; Nayebi, AR; Rezazadeh, H1
Jain, NK; Kulkarni, SK; Singh, VP1
Krsiak, M; Moravec, V; Votava, M1
Caboche, J; Girault, JA; Hervé, D; Pagès, C; Valjent, E1
Cador, M; Koob, GF; Stinus, L; Zorrilla, EP1
Dziedzicka-Wasylewska, M; Filip, M; Inan, SY; Przegaliński, E; Wydra, K1
Becić, F; Begović, A; Zulić, I1
Forray, MI; Gysling, K; Sotomayor, R1
Andrade, Ada S; Arthuri, MT; Gameiro, GH; Gameiro, PH; Marcondes, FK; Pereira, LF; Veiga, MC1
Kolb, Y; Nicolas, LB; Prinssen, EP1
Nakashima, K; Nakashima, MN; Sounvoravong, S; Wada, M1
Berger, BD; Raz, S1
Alberati, D; Moreau, JL; Mory, R; Pinard, E; Wettstein, JG1
Clesse, D; Darcq, E; Goeldner, C; Halter, T; Kieffer, BL; Lutz, PE; Ouagazzal, AM1
Altun, A; Bagcivan, I; Durmus, N; Gursoy, S; Ozdemir, E1
Martin, WJ; Obedencio, GP; Shen, F; Smith, JA; Tsuruda, PR1
Kearney, T; Wu, AH1
Fueki, A; Haga, Y; Hayakawa, A; Ikarashi, N; Kon, R; Kusunoki, Y; Machida, Y; Ochiai, W; Sugiyama, K; Tajima, M1
Kosiorek-Witek, A; Makulska-Nowak, HE1
Barete, S; Consoli, A; Cravero, C; Guinchat, V1
Barakat, A; Elbadr, MM; Hamdy, MM1
Guo, D; Guo, J; Huang, S; Li, Q; Polli, JE; Shu, Y; Xiong, Z; Ye, Z; Zhang, W; Zhou, H; Zhu, P1
Davoudi, S; Dolatshahi, M; Ghorbanzadeh, B; Naserzadeh, R; Paridar, Y1

Reviews

1 review(s) available for fluoxetine and morphine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for fluoxetine and morphine

ArticleYear
Interactions between fluoxetine and opiate analgesia for postoperative dental pain.
    Pain, 1994, Volume: 58, Issue:1

    Topics: Adult; Double-Blind Method; Drug Interactions; Female; Fluoxetine; Humans; Male; Molar, Third; Morphine; Pain, Postoperative; Pentazocine; Premedication; Tooth Extraction

1994
Morphine-fluoxetine interactions in healthy volunteers: analgesia and side effects.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:11

    Topics: Adult; Analgesia; Analgesics, Opioid; Drug Synergism; Fluoxetine; Humans; Morphine; Nausea; Selective Serotonin Reuptake Inhibitors

2000

Other Studies

49 other study(ies) available for fluoxetine and morphine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Do opioids evoke the release of serotonin in the spinal cord? An in vivo microdialysis study of the regulation of extracellular serotonin in the rat.
    Pain, 1992, Volume: 48, Issue:3

    Topics: Amphetamine; Animals; Dialysis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Extracellular Space; Fluoxetine; Hydroxyindoleacetic Acid; Injections, Intraventricular; Male; Morphine; Narcotics; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Serotonin; Spinal Cord; Tetrodotoxin

1992
Intrathecal administration of thiorphan, bestatin, desipramine and fluoxetine differentially potentiate the antinociceptive effects induced by beta-endorphin and morphine, administered intracerebroventricularly.
    Neuropharmacology, 1990, Volume: 29, Issue:3

    Topics: Analgesics; Animals; beta-Endorphin; Desipramine; Fluoxetine; Injections, Intraventricular; Injections, Spinal; Leucine; Male; Mice; Mice, Inbred ICR; Morphine; Reaction Time; Thiorphan

1990
Modification of quasi-morphine withdrawal with serotonin agonists and antagonists: evidence for a role of serotonin in the expression of opiate withdrawal.
    Psychopharmacology, 1989, Volume: 98, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 5-Hydroxytryptophan; Animals; Fluoxetine; Male; Methysergide; Mianserin; Morphine; Piperidines; Rats; Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome

1989
The effect of amfonelic acid or nisoxetine in combination with morphine on brain-stimulation reward.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Male; Morphine; Nalidixic Acid; Naphthyridines; Norepinephrine; Rats; Rats, Inbred F344; Reward; Sensory Thresholds

1989
Effect of chronic treatment with tricyclic antidepressants upon antinociception induced by intrathecal injection of morphine and monoamines.
    Neuropharmacology, 1988, Volume: 27, Issue:1

    Topics: Analgesia; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Desipramine; Drug Interactions; Fluoxetine; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Time Factors

1988
An investigation of tolerance to the actions of leptogenic and anorexigenic drugs in mice.
    Life sciences, 1987, Nov-02, Volume: 41, Issue:18

    Topics: Amphetamine; Animals; Appetite Depressants; Body Weight; Calcitonin; Dextroamphetamine; Drug Tolerance; Eating; Fluoxetine; Mice; Morphine; Naltrexone; Neurotransmitter Agents

1987
Differential analgetic actions of amphetamine enantiomers in the mouse: a drug-drug interaction study.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:2

    Topics: Amphetamine; Analgesics; Animals; Dextroamphetamine; Dopamine; Drug Interactions; Fenclonine; Fluoxetine; Male; Metergoline; Mice; Morphine; Naloxone; Norepinephrine; Pimozide; Serotonin; Stereoisomerism

1985
Fluoxetine, a selective inhibitor of serotonin uptake, potentiates morphine analgesia without altering its discriminative stimulus properties or affinity for opioid receptors.
    Life sciences, 1985, Jun-17, Volume: 36, Issue:24

    Topics: Animals; Binding, Competitive; Brain; Discrimination, Psychological; Drug Synergism; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Female; Fluoxetine; Male; Morphine; Naloxone; Pain; Propylamines; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin

1985
Differential ontogeny of opioid, dopaminergic and serotonergic regulation of prolactin secretion.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3

    Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Corticosterone; Cyproheptadine; Fluoxetine; Growth Hormone; Morphine; p-Chloroamphetamine; Piperazines; Prolactin; Propylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Receptors, Serotonin

1987
Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Analgesia; Animals; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Drinking; Drug Synergism; Fluoxetine; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Morphine; p-Chloroamphetamine; Pain Measurement; Propylamines; Rats; Serotonin; Stereoisomerism; Structure-Activity Relationship

1988
Potentiation of morphine analgesia by D-amphetamine is mediated by norepinephrine and not dopamine.
    Pain, 1988, Volume: 33, Issue:3

    Topics: Amphetamine; Analgesics; Animals; Dopamine; Dopamine Antagonists; Drug Synergism; Electric Stimulation; Escape Reaction; Fluoxetine; Morphine; Nalidixic Acid; Naphthyridines; Norepinephrine; Pain; Reaction Time; Reticular Formation

1988
Prolactin release and tuberoinfundibular dopaminergic neuronal activity following single and double injections of morphine.
    Brain research, 1986, Aug-27, Volume: 381, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Dopamine; Fluoxetine; Growth Hormone; Hypothalamus; Injections, Subcutaneous; Male; Morphine; Neurons; Prolactin; Rats; Rats, Inbred Strains

1986
Meperidine-induced hypothermia in the rat.
    Neuropharmacology, 1982, Volume: 21, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Drug Interactions; Female; Fluoxetine; Meperidine; Morphine; Rats; Rats, Inbred Strains; Time Factors

1982
Serotonin modulation of pain responsiveness in the aged rat.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:2

    Topics: Aging; Animals; Drug Synergism; Fluoxetine; Male; Methysergide; Morphine; Pain; Pain Measurement; Rats; Rats, Inbred F344; Reaction Time; Serotonin

1994
Gender-related differences exist in cortical [3H]nisoxetine binding and are not affected by prenatal morphine exposure.
    Neuroscience, 1997, Volume: 76, Issue:2

    Topics: Analgesics, Opioid; Animals; Cerebral Cortex; Female; Fluoxetine; Hypothalamus; Kinetics; Male; Morphine; Nerve Endings; Norepinephrine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Characteristics

1997
Interactions between different antidepressants and morphine alter gastrointestinal transit in mice.
    Life sciences, 1997, Volume: 61, Issue:9

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Gastrointestinal Transit; Male; Mianserin; Mice; Mice, Inbred ICR; Morphine; Naloxone; Narcotic Antagonists; Rats

1997
Fluoxetine attenuates morphine-induced locomotion and blocks morphine-sensitization.
    European journal of pharmacology, 1997, Oct-22, Volume: 337, Issue:2-3

    Topics: Analysis of Variance; Animals; Depression, Chemical; Fluoxetine; Male; Morphine; Motor Activity; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors

1997
Fluoxetine blocks expression but not development of sensitization to morphine-induced oral stereotypy in rats.
    Psychopharmacology, 1999, Sep-01, Volume: 146, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dopamine; Fluoxetine; Male; Morphine; Motor Activity; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Stereotypic Movement Disorder

1999
Augmented accumbal serotonin levels decrease the preference for a morphine associated environment during withdrawal.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Psychological; Drug Administration Schedule; Environment, Controlled; Fluoxetine; Head Movements; Male; Morphine; Morphine Dependence; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome

2001
Effect of chronic and acute administration of fluoxetine and its additive effect with morphine on the behavioural response in the formalin test in rats.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Analgesics, Opioid; Animals; Drug Synergism; Fluoxetine; Formaldehyde; Injections, Intraperitoneal; Male; Morphine; Naloxone; Narcotic Antagonists; Pain Measurement; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Time Factors

2001
On the antinociceptive effect of fluoxetine, a selective serotonin reuptake inhibitor.
    Brain research, 2001, Oct-12, Volume: 915, Issue:2

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Hot Temperature; Humans; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Morphine; Pain Measurement; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

2001
Effects of alprazolam and fluoxetine on morphine sensitization in mice.
    Physiological research, 2002, Volume: 51, Issue:4

    Topics: Alprazolam; Animals; Fluoxetine; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Narcotic Antagonists; Narcotics

2002
Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.
    The European journal of neuroscience, 2004, Volume: 19, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Benzazepines; Brain; Caffeine; Central Nervous System Stimulants; Cocaine; Desipramine; Dopamine Antagonists; Dronabinol; Enzyme Activation; Fluoxetine; Immunohistochemistry; Male; Mice; Mitogen-Activated Protein Kinases; Morphine; Muscarinic Antagonists; Neurons; Nicotine; Nicotinic Agonists; Scopolamine; Selective Serotonin Reuptake Inhibitors

2004
Buprenorphine and a CRF1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:1

    Topics: Acamprosate; Analgesics, Opioid; Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Buprenorphine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Implants; Fluoxetine; Lisuride; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Substance Withdrawal Syndrome; Taurine

2005
Opioid and monoamine systems mediate the discriminative stimulus of tramadol in rats.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Adrenergic Uptake Inhibitors; Analgesics, Opioid; Animals; Antidepressive Agents; Biogenic Monoamines; Conditioning, Operant; Cyclohexanols; Cyclopropanes; Discrimination, Psychological; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Milnacipran; Morphine; Morpholines; Naloxone; Narcotic Antagonists; Nomifensine; Rats; Rats, Wistar; Reboxetine; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Sodium Chloride; Tramadol; Venlafaxine Hydrochloride

2004
Testing of analgesic effect of fluoxetine.
    Bosnian journal of basic medical sciences, 2004, Volume: 4, Issue:4

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluoxetine; Male; Mice; Morphine; Pain Threshold; Selective Serotonin Reuptake Inhibitors

2004
Acute morphine administration increases extracellular DA levels in the rat lateral septum by decreasing the GABAergic inhibitory tone in the ventral tegmental area.
    Journal of neuroscience research, 2005, Jul-01, Volume: 81, Issue:1

    Topics: Analysis of Variance; Animals; Dopamine; Drug Administration Schedule; Extracellular Fluid; Fluoxetine; gamma-Aminobutyric Acid; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neural Pathways; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Septum of Brain; Serotonin; Statistics, Nonparametric; Ventral Tegmental Area

2005
Nociception- and anxiety-like behavior in rats submitted to different periods of restraint stress.
    Physiology & behavior, 2006, Apr-15, Volume: 87, Issue:4

    Topics: Acute Disease; Adrenocorticotropic Hormone; Analgesics, Opioid; Animals; Anxiety; Chronic Disease; Cortisone; Disease Models, Animal; Emotions; Exploratory Behavior; Fluoxetine; Male; Morphine; Pain; Pain Threshold; Rats; Rats, Wistar; Receptors, Opioid; Restraint, Physical; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Time Factors

2006
A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants.
    European journal of pharmacology, 2006, Oct-10, Volume: 547, Issue:1-3

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Haloperidol; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Morphine; Motor Activity; Obsessive-Compulsive Disorder; Pyridines; Reproducibility of Results; Species Specificity; Spiro Compounds

2006
Modification of antiallodynic and antinociceptive effects of morphine by peripheral and central action of fluoxetine in a neuropathic mice model.
    Acta biologica Hungarica, 2007, Volume: 58, Issue:4

    Topics: Analgesics; Analysis of Variance; Animals; Drug Therapy, Combination; Fluoxetine; Ligation; Male; Mice; Morphine; Neuralgia; Sciatic Nerve; Selective Serotonin Reuptake Inhibitors

2007
Effects of fluoxetine and PCPA on isolation-induced morphine self-administration and startle reactivity.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:1

    Topics: Animals; Fenclonine; Fluoxetine; Male; Morphine; Random Allocation; Rats; Rats, Wistar; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Self Administration; Social Isolation

2010
Pharmacological evaluation of a novel assay for detecting glycine transporter 1 inhibitors and their antipsychotic potential.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 97, Issue:2

    Topics: Aminoquinolines; Animals; Antipsychotic Agents; Binding Sites; Binding, Competitive; Brain Chemistry; Cell Line; Cricetinae; Cricetulus; DNA, Complementary; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fluoxetine; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Male; Membranes; Mice; Morphine; Motor Activity; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors

2010
Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine.
    Biological psychiatry, 2011, Feb-01, Volume: 69, Issue:3

    Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Disease Models, Animal; Drug Evaluation, Preclinical; Emotions; Fluoxetine; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Prosencephalon; Raphe Nuclei; Serotonin; Social Behavior; Substance Withdrawal Syndrome; Time Factors

2011
Effects of fluoxetine and LY 367265 on tolerance to the analgesic effect of morphine in rats.
    Acta physiologica Hungarica, 2011, Volume: 98, Issue:2

    Topics: Analgesics, Opioid; Animals; Cyclic S-Oxides; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Fluoxetine; Hot Temperature; Male; Models, Animal; Morphine; Pain Threshold; Rats; Rats, Wistar; Serotonin Antagonists; Thiadiazoles; Time Factors

2011
Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Analgesia; Animals; Atomoxetine Hydrochloride; Biogenic Monoamines; Chromatography, Liquid; Drug Synergism; Duloxetine Hydrochloride; Fluoxetine; Formaldehyde; Morphine; Morpholines; Neurotransmitter Uptake Inhibitors; Nociceptive Pain; Norepinephrine Plasma Membrane Transport Proteins; Ondansetron; Propylamines; Rats; Rotarod Performance Test; Serotonin Plasma Membrane Transport Proteins; Tandem Mass Spectrometry; Thiophenes

2013
Lack of impairment due to confirmed codeine use prior to a motor vehicle accident: role of pharmacogenomics.
    Journal of forensic and legal medicine, 2013, Volume: 20, Issue:8

    Topics: Accidents, Traffic; Analgesics, Opioid; Bupropion; Codeine; Cytochrome P-450 CYP2D6; Dopamine Uptake Inhibitors; Female; Fluoxetine; Forensic Toxicology; Genetic Carrier Screening; Genotype; Glucuronosyltransferase; Humans; Migraine Disorders; Morphine; Pharmacogenetics; Phenotype; Selective Serotonin Reuptake Inhibitors

2013
Morphine-Induced Constipation Develops With Increased Aquaporin-3 Expression in the Colon via Increased Serotonin Secretion.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 145, Issue:2

    Topics: Analgesics, Opioid; Animals; Aquaporin 3; Colon; Constipation; Defecation; Disease Models, Animal; Fluoxetine; HT29 Cells; Humans; Male; Mercuric Chloride; Morphine; PPAR gamma; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Up-Regulation; Water

2015
Morphine Analgesia Modification in Normotensive and Hypertensive Female Rats after Repeated Fluoxetine Administration.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 118, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Estrous Cycle; Female; Fluoxetine; Hypertension; Male; Morphine; Pain Threshold; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Sex Characteristics; Species Specificity

2016
Cornelia de Lange and Ehlers-Danlos: comorbidity of two rare syndromes.
    BMJ case reports, 2016, Feb-01, Volume: 2016

    Topics: Adult; Anemia, Iron-Deficiency; Antidepressive Agents, Second-Generation; Cognitive Behavioral Therapy; Comorbidity; De Lange Syndrome; Depression; Ehlers-Danlos Syndrome; Fluoxetine; Follow-Up Studies; Hospitalization; Humans; Male; Massage; Morphine; Pain; Pain Management; Problem Behavior; Self Mutilation; Treatment Outcome

2016
Fluoxetine uses in nociceptive pain management: a promising adjuvant to opioid analgesics.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:5

    Topics: Analgesics, Opioid; Animals; Drug Synergism; Fluoxetine; Male; Mice; Mice, Inbred BALB C; Morphine; Nociceptive Pain; Pain Measurement; Pain Threshold; Selective Serotonin Reuptake Inhibitors

2018
Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Pharmaceutical research, 2018, Oct-25, Volume: 35, Issue:12

    Topics: Amitriptyline; Animals; Drug Interactions; Fluoxetine; HEK293 Cells; Humans; Imipramine; Irinotecan; Mice, Inbred C57BL; Morphine; Narcotics; Ondansetron; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Tissue Distribution; Verapamil

2018
Pharmacological evidence for the involvement of the opioid system in the antidepressant-like effect of simvastatin in mice: Without tolerance and withdrawal syndrome.
    Neuroscience letters, 2020, 01-01, Volume: 714

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Behavior, Animal; Depression; Drug Tolerance; Fluoxetine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Locomotion; Mice; Morphine; Naloxone; Narcotic Antagonists; Open Field Test; Receptors, Opioid; Simvastatin; Substance Withdrawal Syndrome; Swimming

2020