fluoxetine and monocrotaline

fluoxetine has been researched along with monocrotaline in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Brodde, OE; Leineweber, K; Seyfarth, T1
Beilfuss, A; Brandt, K; Brodde, OE; Heinroth-Hoffmann, I; Leineweber, K; Pönicke, K; Wludyka, B1
Adnot, S; Benferhat, R; Eddahibi, S; Guignabert, C; Hamon, M; Raffestin, B; Raoul, W; Rideau, D; Zadigue, P1
Wang, HL; Zhai, FG; Zhang, XH1
Huang, J; Mao, ZF; Wang, JY; Zhu, SP1
Han, DD; Li, XQ; Wang, HL; Wang, HM; Yang, CG; Zhang, XH1
Han, DD; Liu, M; Wang, HL; Wang, HM; Wang, Y; Zhang, XH1
Wang, HL; Wang, Y; Zhang, XH1
Han, DD; Liu, JR; Wang, HL; Wang, Y; Zhang, XH1
Bai, Y; Liu, M; Sun, YX; Wang, HL; Wang, HM; Wang, Y; Zhang, XH1
Abid, S; Adnot, S; Amsellem, V; Dubois-Randé, JL; Houssaini, A; Marcos, E; Mouraret, N; Rideau, D; Saker, M; Tissot, CM; Wan, F1
Fujii, Y; Gray, EA; Pearson, JT; Schwenke, DO; Shirai, M; Sonobe, T; Tsuchimochi, H; Umetani, K; Yoshimoto, M1
Bai, Y; Liu, M; Song, ZH; Wang, HL; Wang, HM; Wang, Y1

Other Studies

15 other study(ies) available for fluoxetine and monocrotaline

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Heart Failure; Heart Ventricles; Hypertrophy; In Vitro Techniques; Male; Membranes; Monocrotaline; Norepinephrine; Piperazines; Rats; Rats, Wistar; Tritium

2000
Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.
    Circulation research, 2002, Nov-29, Volume: 91, Issue:11

    Topics: Animals; Binding, Competitive; Cell Membrane; Disease Models, Animal; Eye Proteins; Fluoxetine; G-Protein-Coupled Receptor Kinase 1; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Size; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Rhodopsin; Symporters

2002
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats.
    Circulation, 2005, May-31, Volume: 111, Issue:21

    Topics: Animals; Cell Proliferation; Fluoxetine; Hypertension, Pulmonary; Lung; Monocrotaline; Muscle, Smooth, Vascular; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Up-Regulation

2005
Fluoxetine protects against monocrotaline-induced pulmonary arterial hypertension: potential roles of induction of apoptosis and upregulation of Kv1.5 channels in rats.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:8

    Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Hypertension, Pulmonary; Kv1.5 Potassium Channel; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Time Factors; Up-Regulation

2009
Continuous fluoxetine administration prevents recurrence of pulmonary arterial hypertension and prolongs survival in rats.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:8

    Topics: Animals; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Time Factors

2009
Fluoxetine inhibited extracellular matrix of pulmonary artery and inflammation of lungs in monocrotaline-treated rats.
    Acta pharmacologica Sinica, 2011, Volume: 32, Issue:2

    Topics: Animals; Cytokines; Disease Models, Animal; Extracellular Matrix; Familial Primary Pulmonary Hypertension; Fluoxetine; Hypertension, Pulmonary; Inflammation; Lung; Male; Matrix Metalloproteinase Inhibitors; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Tissue Inhibitor of Metalloproteinases

2011
Downregulation of osteopontin is associated with fluoxetine amelioration of monocrotaline-induced pulmonary inflammation and vascular remodelling.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Down-Regulation; Fluoxetine; Inflammation; Lung; Lung Diseases; Monocrotaline; Osteopontin; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Inbred WF; Selective Serotonin Reuptake Inhibitors

2011
Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:5

    Topics: Animals; Apoptosis; beta Catenin; Blood Pressure; Bone Morphogenetic Protein Receptors, Type II; Caspase 3; Cyclic GMP-Dependent Protein Kinases; Endothelial Cells; Fluoxetine; Gene Expression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Microvessels; Monocrotaline; Phosphorylation; Pulmonary Artery; Rats; Rats, Wistar; Smad1 Protein

2011
Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:4

    Topics: Animals; Antihypertensive Agents; Cell Proliferation; Disease Models, Animal; Fluoxetine; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Male; MAP Kinase Signaling System; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vascular Endothelial Growth Factor A

2012
Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:11

    Topics: Airway Remodeling; Animals; Disease Models, Animal; Down-Regulation; Familial Primary Pulmonary Hypertension; Fluoxetine; Hypertension, Pulmonary; Isoenzymes; Lung; Male; MAP Kinase Signaling System; Monocrotaline; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Selective Serotonin Reuptake Inhibitors

2012
Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension.
    American journal of respiratory cell and molecular biology, 2013, Volume: 48, Issue:5

    Topics: Animals; Apoptosis; Benzamides; Cell Proliferation; Cells, Cultured; Fluoxetine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypertension, Pulmonary; Imatinib Mesylate; Male; Monocrotaline; Myocytes, Smooth Muscle; Phosphorylation; Piperazines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Pyrimidines; Rats; Rats, Wistar; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases

2013
Assessment of the serotonin pathway as a therapeutic target for pulmonary hypertension.
    Journal of synchrotron radiation, 2013, Volume: 20, Issue:Pt 5

    Topics: Acetylcholine; Angiography; Animals; Disease Models, Animal; Endothelium, Vascular; Fluoxetine; Humans; Hypertension, Pulmonary; Lung; Male; Molecular Targeted Therapy; Monocrotaline; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Vasodilation

2013
Involvement of S100A4/Mts1 and associated proteins in the protective effect of fluoxetine against MCT - Induced pulmonary hypertension in rats.
    Journal of the Chinese Medical Association : JCMA, 2018, Volume: 81, Issue:12

    Topics: Animals; Dose-Response Relationship, Drug; Fluoxetine; Hypertension, Pulmonary; Male; Monocrotaline; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; S100 Calcium-Binding Protein A4; Tumor Suppressor Protein p53

2018