fluoxetine and mirtazapine

fluoxetine has been researched along with mirtazapine in 85 studies

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.18)18.7374
1990's11 (12.94)18.2507
2000's34 (40.00)29.6817
2010's33 (38.82)24.3611
2020's6 (7.06)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cortizo, L; García, N; Innerárity, A; Labeaga, L; Mosquera, R; Orjales, A; Pumar, MC; Toledo, A1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Buck, LB; Petrascheck, M; Ye, X1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Alix, K; Dukat, M; Khatri, S; Schulte, MK; Worsham, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Smith, DF1
Berendsen, HH; Broekkamp, CL1
Pinder, RM1
Kremer, CM; Timmerman, L; van Moffaert, M; Wheatley, DP1
Benazzi, F1
Farah, A1
Montgomery, SA1
Thompson, C1
Nutt, DJ1
Thase, ME1
Brown, MC; Guest, JF; Nimmerrichter, AA1
Häggström, L; Nordling, S; Norinder, A1
Borghi, J; Guest, JF1
Gorman, JM; Nierenberg, AA; Stahl, SM1
Kremer, C; Quitkin, FM; Taylor, BP1
Nierenberg, AA1
Busnello, EA; Busnello, JV; Kapczinski, F; Kauer-Sant'Anna, M; Madruga, M; Quevedo, J; Ribeiro, L1
Ng, B1
Bouvard, M; Rénéric, JP; Stinus, L2
Biggio, G; Dazzi, L; Pisul, MG; Purdy, RH; Serra, M1
Lima, L; Urbina, M1
Chen, CC; Hong, CJ; Hsiao, CC; Hu, WH; Ruwe, FJ; Tsai, SJ1
Cormier, JL; DeMartinis, NA; Gary, EM; Gary, KA; McNally, DP; Winokur, A1
Drobizhev, MIu; Kozyrev, VN; Kraeva, GK; Kubrakov, MA; Smulevich, AB1
Bateman, DN; Chick, J; Good, AM; Kelly, CA; Masterton, G1
Norman, TR; Olver, JS1
Lawrence, RW1
Moreno, R; Ramakers-van Moorsel, CJ; Schutte, AJ; Versiani, M1
Aghayan, S; Akhondzadeh, S; Amini, H; Jalili, SA; Pakravan-Nejad, M; Yahyazadeh, O1
Cela, R; Garcia-Jares, C; Lamas, JP; Llompart, M; Salgado-Petinal, C1
Lambert, WE; Maudens, KE; Van Peteghem, CH; Wille, SM1
Albertazzi, P1
Fountoulakis, KN; Iacovides, A; Kaprinis, GS; Koumaris, V; Siamouli, M1
Arana-Lechuga, Y; Prospero-Garcia, KA; Ramirez-Bermudez, J; Teran-Perez, G; Torres-Ruiz, A; Velazquez-Moctezuma, J1
Connor, K; Davidson, JR; Vaishnavi, S1
Olivier, B; Schweitzer, DH; Waldinger, MD; Zwinderman, AH1
Liang, KY; Liao, SC; Liu, CC1
Jia, L; Li, YY; Shang, YY1
Bergeron, R; Blier, P; Hébert, C; Laberge, L; Tremblay, P; Ward, HE1
Rush, AJ1
Beauclair, L; Desmarais, JE; Margolese, HC; Wolf, Y1
Nierenberg, AA; Schutte, AJ; Simmons, JH; Thase, ME; van Oers, HJ; Vrijland, P1
Agius, M; Gardner, J; Liu, K; Zaman, R1
Fonseca, C; Laino, CH; Reinés, A; Slobodianik, N; Sterin-Speziale, N1
Fisar, Z; Hroudová, J; Raboch, J1
Iwamura, T; Kasai, M; Kato, S; Nisijima, K; Shioda, K; Yoshino, T1
Cabral, A; Ferreira, LS; Izídio, GS; Macedo, PT; Melo, TG; Ribeiro, AM; Silva, RH; Sousa, DS1
Johansen, SS; Nielsen, MK1
Fan, DS; Guo, L; Ji, CX; Li, W; Liang, ZL; Xu, RM; Zhang, JJ1
Arterburn, D; Bogart, A; Boudreau, DM; Haneuse, S; Simon, G; Theis, MK; Westbrook, E1
Gądek-Michalska, A; Kabziński, M; Rachwalska, P; Rogóż, Z; Sadaj, W1
Clarke, G; Cryan, JF; Dinan, TG; Griffin, BT; O'Brien, FE1
Arteta, B; Basta-Kaim, A; Budziszewska, B; Curzytek, K; Duda, W; Grygier, B; Kubera, M; Lasoń, W; Leśkiewicz, M; Maes, M1
Purslow, C1
Abe, M; Mori, Y; Nakata, S; Ochi, S; Ueno, S; Yamazaki, K; Yoshino, Y1
Andersson, SI; Broaddus, CD; Gomez-Amaro, RL; Kardakaris, R; Niculescu, AB; Petrascheck, M; Rangaraju, S; Solis, GM1
García-Fuster, MJ; García-Sevilla, JA1
Cipriani, A; Coghill, D; Cohen, D; Cuijpers, P; Del Giovane, C; Hazell, P; Hetrick, SE; Leucht, S; Liu, L; Liu, Y; Michael, KD; Pu, J; Qin, B; Ravindran, AV; Whittington, C; Xie, P; Yang, L; Zhang, Y; Zhou, X1
Kamińska, K; Pańczyszyn-Trzewik, P; Rogóż, Z; Sowa-Kućma, M1
Bahar, MA; Bos, JHJ; Hak, E; Wang, Y; Wilffert, B1
Carleton, BC; Etminan, M; Guo, MY; Kezouh, A; Kim, DD; Procyshyn, RM; Samii, A1
Feng, S; Gu, J; Jiang, X; Tang, S; Wang, L; Zheng, L1
Bacon, F; Clarke, CS; Donkor, Y; Duffy, L; Freemantle, N; Gilbody, S; Hunter, R; Kendrick, T; Kessler, D; King, M; Lanham, P; Lewis, G; Mangin, D; Marston, L; Moore, M; Nazareth, I; Wiles, N1
Cen, M; Dai, N; Du, L; Luo, L; Shen, J1
Chen, C; Shan, W1
Badcock, PB; Bailey, AP; Cox, GR; Hetrick, SE; McKenzie, JE; Meader, N; Merry, SN; Moller, CI; Sharma, V1
Koziorowski, M; Mytych, J; Sołek, P; Tabęcka-Łonczyńska, A1
Hatano, M; Ikuta, T; Iwata, N; Kishi, T; Matsuda, Y; Okuya, M; Sakuma, K1
Arteta, B; Curzytek, K; Grygier, B; Kubera, M; Maes, M; Malicki, S1
Keidan, L; Pick, CG; Schreiber, S1
Chen, L; Fan, H; Hu, Q; Li, K; Liu, X; Shi, Y; Wu, K; Zhong, J; Zhou, J1

Reviews

16 review(s) available for fluoxetine and mirtazapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New developments in the treatment of depression.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 14

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Placebos; Severity of Illness Index; Treatment Outcome

1999
Mirtazapine versus selective serotonin reuptake inhibitors.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Antidepressive Agents, Tricyclic; Citalopram; Clinical Trials as Topic; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1999
Care of depressed patients with anxiety symptoms.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Citalopram; Clinical Trials as Topic; Comorbidity; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

1999
Antidepressant treatment of the depressed patient with insomnia.
    The Journal of clinical psychiatry, 1999, Volume: 60 Suppl 17

    Topics: Antidepressive Agents, Tricyclic; Comorbidity; Cyclohexanols; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Piperazines; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

1999
Cost-effectiveness of mirtazapine compared to amitriptyline and fluoxetine in the treatment of moderate and severe depression in austria.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Austria; Cost-Benefit Analysis; Depressive Disorder; Double-Blind Method; Drug Hypersensitivity; Fluoxetine; Humans; Mianserin; Mirtazapine; Retrospective Studies; Severity of Illness Index

1999
[Treatment of depression and cost efficiency. The cost of a tablet is a poor indicator seen from a socioeconomic perspective].
    Lakartidningen, 2000, Apr-05, Volume: 97, Issue:14

    Topics: Adrenergic alpha-Agonists; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Cost of Illness; Cost-Benefit Analysis; Depression; Drug Costs; Fluoxetine; Histamine H1 Antagonists; Humans; Mianserin; Mirtazapine; Models, Economic; Socioeconomic Factors; Sweden

2000
Evidence of early onset of antidepressant effect in randomized controlled trials.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 4

    Topics: Antidepressive Agents; Citalopram; Cyclohexanols; Depressive Disorder; Drug Administration Schedule; Fluoxetine; Humans; Mianserin; Mirtazapine; Personality Inventory; Placebos; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome; Venlafaxine Hydrochloride

2001
Do some antidepressants work faster than others?
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 15

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Cyclohexanols; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Venlafaxine Hydrochloride

2001
New formulations of existing antidepressants: advantages in the management of depression.
    CNS drugs, 2004, Volume: 18, Issue:8

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Chemistry, Pharmaceutical; Cyclohexanols; Delayed-Action Preparations; Depression; Drug Evaluation; Fluoxetine; Humans; Mianserin; Mirtazapine; Molecular Conformation; Venlafaxine Hydrochloride

2004
Noradrenergic and serotonergic modulation to treat vasomotor symptoms.
    The journal of the British Menopause Society, 2006, Volume: 12, Issue:1

    Topics: Citalopram; Cyclohexanols; Female; Fluoxetine; Hot Flashes; Humans; Menopause; Mianserin; Mirtazapine; Paroxetine; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Trazodone; Venlafaxine Hydrochloride

2006
Remission with mirtazapine and selective serotonin reuptake inhibitors: a meta-analysis of individual patient data from 15 controlled trials of acute phase treatment of major depression.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Fluoxetine; Fluvoxamine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Patient Dropouts; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Remission Induction; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome; Young Adult

2010
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
    Lancet (London, England), 2016, Aug-27, Volume: 388, Issue:10047

    Topics: Adolescent; Amitriptyline; Antidepressive Agents; Bayes Theorem; Child; Citalopram; Clomipramine; Confounding Factors, Epidemiologic; Depressive Disorder, Major; Desipramine; Double-Blind Method; Drug Administration Schedule; Duloxetine Hydrochloride; Evidence-Based Medicine; Fluoxetine; Humans; Imipramine; Mianserin; Mirtazapine; Nortriptyline; Paroxetine; Piperazines; Randomized Controlled Trials as Topic; Research Design; Sertraline; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2016
Pharmacological and non-pharmacological treatments for major depressive disorder in adults: A systematic review and network meta-analysis.
    Psychiatry research, 2019, Volume: 281

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Bupropion; Cognitive Behavioral Therapy; Depressive Disorder, Major; Fluoxetine; Humans; Mirtazapine; Network Meta-Analysis; Treatment Outcome; Venlafaxine Hydrochloride; Vortioxetine

2019
New generation antidepressants for depression in children and adolescents: a network meta-analysis.
    The Cochrane database of systematic reviews, 2021, 05-24, Volume: 5

    Topics: Adolescent; Antidepressive Agents; Bias; Child; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Mirtazapine; Network Meta-Analysis; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Suicidal Ideation; Venlafaxine Hydrochloride; Vilazodone Hydrochloride; Vortioxetine

2021
Antidepressants for the treatment of adults with major depressive disorder in the maintenance phase: a systematic review and network meta-analysis.
    Molecular psychiatry, 2023, Volume: 28, Issue:1

    Topics: Adult; Amitriptyline; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Desvenlafaxine Succinate; Duloxetine Hydrochloride; Female; Fluoxetine; Fluvoxamine; Humans; Mirtazapine; Network Meta-Analysis; Paroxetine; Randomized Controlled Trials as Topic; Reboxetine; Sertraline; Venlafaxine Hydrochloride; Vortioxetine

2023

Trials

11 trial(s) available for fluoxetine and mirtazapine

ArticleYear
Mirtazapine: efficacy and tolerability in comparison with fluoxetine in patients with moderate to severe major depressive disorder. Mirtazapine-Fluoxetine Study Group.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:6

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug Administration Schedule; Female; Fluoxetine; Headache; Health Status; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Nausea; Psychiatric Status Rating Scales; Quality of Life; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Sleep

1998
Relief of SSRI-induced sexual dysfunction with mirtazapine treatment.
    The Journal of clinical psychiatry, 1999, Volume: 60, Issue:4

    Topics: Adult; Antidepressive Agents, Tricyclic; Anxiety Disorders; Drug Therapy, Combination; Female; Fluoxetine; Humans; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sexual Dysfunctions, Psychological; Treatment Outcome

1999
Cost-effectiveness of mirtazapine compared to amitriptyline and fluoxetine in the treatment of moderate and severe depression in austria.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Austria; Cost-Benefit Analysis; Depressive Disorder; Double-Blind Method; Drug Hypersensitivity; Fluoxetine; Humans; Mianserin; Mirtazapine; Retrospective Studies; Severity of Illness Index

1999
Mirtazapine versus fluoxetine in the treatment of panic disorder.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2001, Volume: 34, Issue:10

    Topics: Adolescent; Adult; Analysis of Variance; Antidepressive Agents, Tricyclic; Double-Blind Method; Female; Fluoxetine; Humans; Male; Mianserin; Mirtazapine; Panic Disorder; Selective Serotonin Reuptake Inhibitors

2001
A double-blind, randomized, group-comparative study of the tolerability and efficacy of 6 weeks' treatment with mirtazapine or fluoxetine in depressed Chinese patients.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:8

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Ethnicity; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Taiwan; Treatment Outcome

2003
Comparative effects of mirtazapine and fluoxetine on sleep physiology measures in patients with major depression and insomnia.
    The Journal of clinical psychiatry, 2003, Volume: 64, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Follow-Up Studies; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Polysomnography; Sleep Initiation and Maintenance Disorders; Treatment Outcome

2003
Comparison of the effects of mirtazapine and fluoxetine in severely depressed patients.
    CNS drugs, 2005, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Personality Inventory; Psychiatric Status Rating Scales; Time Factors; Treatment Outcome

2005
Comparison of mirtazapine and fluoxetine in the treatment of major depressive disorder: a double-blind, randomized trial.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Inpatients; Male; Mianserin; Middle Aged; Mirtazapine; Outpatients; Oxazepam; Treatment Outcome

2005
Fluoxetine-mirtazapine interaction may induce restless legs syndrome: report of 3 cases from a clinical trial.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:11

    Topics: Adult; Antidepressive Agents; Depressive Disorder, Major; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Restless Legs Syndrome; Sleep Initiation and Maintenance Disorders

2006
Combination of antidepressant medications from treatment initiation for major depressive disorder: a double-blind randomized study.
    The American journal of psychiatry, 2010, Volume: 167, Issue:3

    Topics: Adult; Antidepressive Agents; Bupropion; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Personality Inventory; Psychometrics; Secondary Prevention; Venlafaxine Hydrochloride

2010
A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long-term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRes
    Trials, 2019, Jun-03, Volume: 20, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Citalopram; Cost-Benefit Analysis; Depression; Double-Blind Method; Fluoxetine; Humans; Middle Aged; Mirtazapine; Outcome Assessment, Health Care; Primary Health Care; Randomized Controlled Trials as Topic; Recurrence; Retrospective Studies; Sample Size; Sertraline

2019

Other Studies

59 other study(ies) available for fluoxetine and mirtazapine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
    Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Reboxetine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character.
    Bioorganic & medicinal chemistry letters, 2013, Nov-01, Volume: 23, Issue:21

    Topics: Amination; Animals; Antidepressive Agents; Anura; Halogenation; Hindlimb Suspension; Mice; Quinazolines; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists

2013
The stereoselectivity of serotonin uptake in brain tissue and blood platelets: the topography of the serotonin uptake area.
    Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1

    Topics: Alanine; Amphetamine; Aniline Compounds; Animals; Antidepressive Agents; Blood Platelets; Brain; Fluoxetine; Humans; Male; Methadone; Mianserin; Mirtazapine; Morpholines; Naphthalenes; Nefopam; Nomifensine; Paroxetine; Piperidines; Rabbits; Serotonin; Stereoisomerism; Tranylcypromine; Viloxazine; Zimeldine

1986
Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine.
    Psychopharmacology, 1997, Volume: 133, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Conditioning, Operant; Fluoxetine; Male; Mianserin; Mice; Mice, Inbred ICR; Mirtazapine; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Taste

1997
The pharmacologic rationale for the clinical use of antidepressants.
    The Journal of clinical psychiatry, 1997, Volume: 58, Issue:11

    Topics: Antidepressive Agents, Tricyclic; Anxiety Disorders; Clinical Trials as Topic; Depressive Disorder; Fluoxetine; Humans; Mianserin; Mirtazapine; Psychiatric Status Rating Scales; Receptors, Adrenergic; Receptors, Serotonin; Treatment Outcome

1997
Serotonin syndrome with mirtazapine-fluoxetine combination.
    International journal of geriatric psychiatry, 1998, Volume: 13, Issue:7

    Topics: Adrenergic alpha-Antagonists; Aged; Antidepressive Agents, Tricyclic; Depression; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome

1998
[Mirtazapin--fast and strong effects].
    Fortschritte der Neurologie-Psychiatrie, 1998, Volume: 66, Issue:10 Suppl M

    Topics: Antidepressive Agents, Tricyclic; Depression; Fluoxetine; Humans; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors

1998
Economic impact of using mirtazapine compared to amitriptyline and fluoxetine in the treatment of moderate and severe depression in the UK.
    European psychiatry : the journal of the Association of European Psychiatrists, 2000, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Cost-Benefit Analysis; Depression; Fluoxetine; Humans; Mianserin; Middle Aged; Mirtazapine; Severity of Illness Index; United Kingdom

2000
Does mirtazapine have a more rapid onset than SSRIs?
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Citalopram; Cross-Sectional Studies; Data Interpretation, Statistical; Depressive Disorder; Double-Blind Method; Fluoxetine; Humans; Mianserin; Mirtazapine; Paroxetine; Patient Dropouts; Placebo Effect; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Research Design; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2001
Mania associated with mirtazapine augmentation of fluoxetine.
    Depression and anxiety, 2002, Volume: 15, Issue:1

    Topics: Adrenergic alpha-Antagonists; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoxetine; Humans; Mianserin; Middle Aged; Mirtazapine; Selective Serotonin Reuptake Inhibitors; Time Factors

2002
In the rat forced swimming test, NA-system mediated interactions may prevent the 5-HT properties of some subacute antidepressant treatments being expressed.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Depression; Dopamine Agents; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Immobilization; Male; Mianserin; Mirtazapine; Motor Activity; Norepinephrine; Oxidopamine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Swimming

2002
Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine.
    Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Second-Generation; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Desoxycorticosterone; Electroshock; Fluoxetine; Male; Mianserin; Mirtazapine; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids; Stress, Psychological

2002
In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs.
    Behavioural brain research, 2002, Nov-15, Volume: 136, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Clonidine; Cyclopropanes; Depression; Desipramine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Motor Activity; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Selective Serotonin Reuptake Inhibitors; Swimming

2002
Serotonin transporter modulation in blood lymphocytes from patients with major depression.
    Cellular and molecular neurobiology, 2002, Volume: 22, Issue:5-6

    Topics: Adrenergic alpha-Antagonists; Adult; Antidepressive Agents, Second-Generation; Brain; Carrier Proteins; Depressive Disorder, Major; Down-Regulation; Female; Fluoxetine; Humans; Lymphocytes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mianserin; Mirtazapine; Nerve Tissue Proteins; Neuroimmunomodulation; Paroxetine; Radioligand Assay; Serotonin; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome; Up-Regulation

2002
[Psychotropic drugs used in a psychiatric hospital (pharmaco-epidemiologic aspects)].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2003, Volume: 103, Issue:11

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Carbazoles; Chlorprothixene; Clopenthixol; Data Collection; Dopamine Antagonists; Female; Fluoxetine; Flupenthixol; Hospitals, Psychiatric; Humans; Male; Mental Disorders; Mianserin; Middle Aged; Mirtazapine; Monoamine Oxidase Inhibitors; Moscow; Nootropic Agents; Olanzapine; Pharmacoepidemiology; Phenothiazines; Psychotropic Drugs; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride

2003
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Overdose; Drug Prescriptions; Emergency Service, Hospital; Female; Fluoxetine; Humans; Imipramine; Information Services; Male; Mianserin; Mirtazapine; Paroxetine; Patient Admission; Patient Readmission; Poison Control Centers; Retrospective Studies; Risk Assessment; Scotland; Selective Serotonin Reuptake Inhibitors; Self-Injurious Behavior; Sertraline; Trazodone; Venlafaxine Hydrochloride

2004
Effect of mirtazapine versus fluoxetine on "sleep quality".
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:8

    Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder; Dose-Response Relationship, Drug; Fluoxetine; Humans; Mianserin; Mirtazapine; Research Design; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Initiation and Maintenance Disorders

2004
Rapid screening of selective serotonin re-uptake inhibitors in urine samples using solid-phase microextraction gas chromatography-mass spectrometry.
    Analytical and bioanalytical chemistry, 2005, Volume: 382, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Fluoxetine; Fluvoxamine; Gas Chromatography-Mass Spectrometry; Humans; Mianserin; Mirtazapine; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sertraline; Solid Phase Microextraction; Venlafaxine Hydrochloride

2005
Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis.
    Journal of chromatography. A, 2005, Dec-09, Volume: 1098, Issue:1-2

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Desvenlafaxine Succinate; Fluoxetine; Gas Chromatography-Mass Spectrometry; Humans; Mianserin; Microchemistry; Mirtazapine; Piperazines; Reproducibility of Results; Sertraline

2005
Successful treatment of anorexia with a combination of high-dose olanzapine, fluoxetine and mirtazapine.
    International journal of clinical pharmacology and therapeutics, 2006, Volume: 44, Issue:9

    Topics: Adult; Anorexia; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; Fluoxetine; Humans; Mianserin; Mirtazapine; Olanzapine; Selective Serotonin Reuptake Inhibitors

2006
An abbreviated version of the Connor-Davidson Resilience Scale (CD-RISC), the CD-RISC2: psychometric properties and applications in psychopharmacological trials.
    Psychiatry research, 2007, Aug-30, Volume: 152, Issue:2-3

    Topics: Antidepressive Agents; Anxiety Disorders; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder, Major; Fluoxetine; Humans; Kava; Mianserin; Mirtazapine; Paroxetine; Psychometrics; Sertraline; Stress Disorders, Post-Traumatic; Surveys and Questionnaires; Venlafaxine Hydrochloride

2007
Geometric mean IELT and premature ejaculation: appropriate statistics to avoid overestimation of treatment efficacy.
    The journal of sexual medicine, 2008, Volume: 5, Issue:2

    Topics: Antidepressive Agents; Coitus; Data Interpretation, Statistical; Ejaculation; Fluoxetine; Fluvoxamine; Humans; Male; Mianserin; Mirtazapine; Models, Biological; Piperazines; Reaction Time; Research Design; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Sertraline; Sexual Dysfunction, Physiological; Treatment Outcome; Triazoles

2008
Antidepressant-associated mania: soon after switch from fluoxetine to mirtazapine in an elderly woman with mixed depressive features.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aged; Bipolar Disorder; Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Fluoxetine; Humans; Mianserin; Mirtazapine; Selective Serotonin Reuptake Inhibitors

2009
Effect of antidepressants on body weight, ethology and tumor growth of human pancreatic carcinoma xenografts in nude mice.
    World journal of gastroenterology, 2008, Jul-21, Volume: 14, Issue:27

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Body Weight; Carcinoma; Cell Line, Tumor; Female; Fluoxetine; Male; Mianserin; Mice; Mice, Inbred BALB C; Mice, Nude; Mirtazapine; Neoplasm Transplantation; Pancreatic Neoplasms

2008
Combining antidepressant medications: a good idea?
    The American journal of psychiatry, 2010, Volume: 167, Issue:3

    Topics: Antidepressive Agents; Bupropion; Cyclohexanols; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Fluoxetine; Humans; Mianserin; Mirtazapine; Randomized Controlled Trials as Topic; Venlafaxine Hydrochloride

2010
Loss of response after switching from brand name to generic formulations: three cases and a discussion of key clinical considerations when switching.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:3

    Topics: Drugs, Generic; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Secondary Prevention; Therapeutic Equivalency; Valproic Acid

2010
An audit to compare discharge rates between antidepressant monotherapies prescribed for pure unipolar depression versus depression in the presence of other indications.
    Psychiatria Danubina, 2010, Volume: 22, Issue:2

    Topics: Adult; Antidepressive Agents; Citalopram; Community Mental Health Centers; Comorbidity; Cyclohexanols; Depressive Disorder; England; Fluoxetine; Guideline Adherence; Humans; Medical Audit; Mianserin; Mirtazapine; Patient Discharge; Practice Patterns, Physicians'; Sertraline; Suicide; Suicide Prevention; Treatment Outcome; Venlafaxine Hydrochloride

2010
Potentiation of omega-3 fatty acid antidepressant-like effects with low non-antidepressant doses of fluoxetine and mirtazapine.
    European journal of pharmacology, 2010, Dec-01, Volume: 648, Issue:1-3

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Fatty Acids, Omega-3; Fluoxetine; Male; Mianserin; Mirtazapine; Rats; Rats, Wistar; Swimming; Time Factors

2010
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:5

    Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride

2010
The effects of mirtazapine and fluoxetine on hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) in rats.
    Neuroscience letters, 2011, Jul-15, Volume: 499, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Fever; Fluoxetine; Male; Mianserin; Mirtazapine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Serotonin 5-HT2 Receptor Antagonists; Serotonin Agents

2011
Antidepressants differentially modify the extinction of an aversive memory task in female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Apr-27, Volume: 37, Issue:1

    Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Extinction, Psychological; Female; Fluoxetine; Maze Learning; Memory; Mianserin; Mirtazapine; Nortriptyline; Psychomotor Performance; Rats; Rats, Wistar

2012
Simultaneous determination of 25 common pharmaceuticals in whole blood using ultra-performance liquid chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2012, Volume: 36, Issue:7

    Topics: Analgesics; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Chromatography, High Pressure Liquid; Clopenthixol; Fluoxetine; Histamine Antagonists; Humans; Limit of Detection; Linear Models; Methotrimeprazine; Methylphenidate; Mianserin; Mirtazapine; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2012
Evaluation of the anti-ulcerogenic activity of the antidepressants duloxetine, amitriptyline, fluoxetine and mirtazapine in different models of experimental gastric ulcer in rats.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Amitriptyline; Animals; Anti-Ulcer Agents; Antidepressive Agents; Disease Models, Animal; Duloxetine Hydrochloride; Fluoxetine; Immersion; Indomethacin; Male; Mianserin; Mirtazapine; Rats; Rats, Sprague-Dawley; Reserpine; Restraint, Physical; Stomach Ulcer; Stress, Psychological; Thiophenes; Water

2012
Influence of body mass index on the choice of therapy for depression and follow-up care.
    Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Body Mass Index; Choice Behavior; Cohort Studies; Depression; Female; Fluoxetine; Follow-Up Studies; Humans; Logistic Models; Male; Mianserin; Middle Aged; Mirtazapine; Obesity; Paroxetine; Psychotherapy; Young Adult

2013
Effect of co-treatment with fluoxetine or mirtazapine and risperidone on the active behaviors and plasma corticosterone concentration in rats subjected to the forced swim test.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Behavior, Animal; Corticosterone; Depression; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Fluoxetine; Male; Mianserin; Mirtazapine; Motor Activity; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Antagonists; Swimming

2012
Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:10

    Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Capillary Permeability; Dogs; Duloxetine Hydrochloride; Fluoxetine; Humans; Imipramine; Madin Darby Canine Kidney Cells; Mianserin; Mirtazapine; Thiophenes; Transfection

2013
Inhibitory effect of antidepressants on B16F10 melanoma tumor growth.
    Pharmacological reports : PR, 2013, Volume: 65, Issue:3

    Topics: Animals; Antidepressive Agents; Cell Proliferation; Desipramine; Fluoxetine; Interleukin-10; Male; Melanoma, Experimental; Mianserin; Mice; Mice, Inbred C57BL; Mirtazapine; T-Lymphocytes; Tumor Cells, Cultured

2013
Linking Clostridium difficile infection with depression.
    Expert review of anti-infective therapy, 2013, Volume: 11, Issue:8

    Topics: Antidepressive Agents; Clostridioides difficile; Clostridium Infections; Depression; Fluoxetine; Humans; Mianserin; Mirtazapine; Risk Factors

2013
Antidepressant action via the nitric oxide system: A pilot study in an acute depressive model induced by arginin.
    Neuroscience letters, 2015, Jul-10, Volume: 599

    Topics: Acute Disease; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Arginine; Cyclopropanes; Depression; Fluoxetine; Male; Mianserin; Milnacipran; Mirtazapine; Nitric Oxide; Nitric Oxide Synthase; Pilot Projects; Rats, Wistar; Selective Serotonin Reuptake Inhibitors

2015
Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non-cell-autonomous stress response.
    Aging cell, 2015, Volume: 14, Issue:6

    Topics: Aging; Animals; Antidepressive Agents, Second-Generation; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catalase; Fluoxetine; Histamine H1 Antagonists; Life Expectancy; Longevity; Mianserin; Mirtazapine; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Superoxide Dismutase; Synaptic Transmission

2015
Effects of anti-depressant treatments on FADD and p-FADD protein in rat brain cortex: enhanced anti-apoptotic p-FADD/FADD ratio after chronic desipramine and fluoxetine administration.
    Psychopharmacology, 2016, Volume: 233, Issue:15-16

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apoptosis; Autoreceptors; Blotting, Western; Brain; CASP8 and FADD-Like Apoptosis Regulating Protein; Cerebral Cortex; Clorgyline; Desipramine; Electroshock; Excitatory Amino Acid Antagonists; Fas-Associated Death Domain Protein; Fluoxetine; Idazoxan; Indans; Ketamine; Male; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Norepinephrine Plasma Membrane Transport Proteins; Phenelzine; Phosphoproteins; Phosphorylation; Rats; RNA-Binding Proteins; Thiazoles

2016
Repeated co-treatment with antidepressants and risperidone increases BDNF mRNA and protein levels in rats.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:5

    Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Citalopram; Drug Interactions; Fluoxetine; Frontal Lobe; Gene Expression Regulation; Hippocampus; Mianserin; Mirtazapine; Rats; Rats, Wistar; Risperidone; RNA, Messenger; Serotonin Antagonists

2017
Discontinuation and dose adjustment of metoprolol after metoprolol-paroxetine/fluoxetine co-prescription in Dutch elderly.
    Pharmacoepidemiology and drug safety, 2018, Volume: 27, Issue:6

    Topics: Aged; Aged, 80 and over; Citalopram; Cohort Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Prescriptions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Metoprolol; Middle Aged; Mirtazapine; Netherlands; Paroxetine

2018
Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study.
    Journal of clinical psychopharmacology, 2018, Volume: 38, Issue:4

    Topics: Antidepressive Agents; Basal Ganglia Diseases; Bupropion; Case-Control Studies; Citalopram; Duloxetine Hydrochloride; Female; Fluoxetine; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Pharmacoepidemiology; Sertraline; United States; Venlafaxine Hydrochloride

2018
In-vitro and in situ assessment of the efflux of five antidepressants by breast cancer resistance protein.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Biological Transport; Blood-Brain Barrier; Brain; Cell Line, Tumor; Duloxetine Hydrochloride; Fluoxetine; Humans; Mirtazapine; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; Sertraline

2019
Benefit of small dose antidepressants for functional dyspepsia: Experience from a tertiary center in eastern China.
    Medicine, 2019, Volume: 98, Issue:41

    Topics: Anthracenes; Antidepressive Agents; China; Citalopram; Drug Combinations; Dyspepsia; Female; Fluoxetine; Flupenthixol; Humans; Male; Middle Aged; Mirtazapine; Postprandial Period; Remission Induction; Retrospective Studies; Treatment Outcome

2019
Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects.
    International journal of molecular sciences, 2021, Nov-01, Volume: 22, Issue:21

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Cell Line; Escitalopram; Fluoxetine; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Imipramine; Male; Mice; Micronuclei, Chromosome-Defective; Mirtazapine; Models, Biological; Olanzapine; Organ Specificity; Reboxetine; Reproduction; Signal Transduction; Spermatogenesis; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Time Factors; Venlafaxine Hydrochloride

2021
Stimulatory effect of fluoxetine and desipramine, but not mirtazapine on C26 colon carcinoma hepatic metastases formation: association with cytokines.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Antidepressive Agents; Carcinoma; Colonic Neoplasms; Cytokines; Desipramine; Fluoxetine; Liver Neoplasms; Male; Mice; Mirtazapine

2023
Treatment-Resistant Depression (TRD): Is the Opioid System Involved?
    International journal of molecular sciences, 2023, Jul-06, Volume: 24, Issue:13

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Mianserin; Mice; Mirtazapine; Moclobemide; Naloxone; Reboxetine; Trazodone; Venlafaxine Hydrochloride

2023
Simultaneous separation and determination of several chiral antidepressants and their enantiomers in wastewater by online heart-cutting two-dimensional liquid chromatography.
    Ecotoxicology and environmental safety, 2023, Sep-15, Volume: 263

    Topics: Antidepressive Agents; Bupropion; Chromatography, High Pressure Liquid; Fluoxetine; Mirtazapine; Stereoisomerism; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2023